DK1000048T3 - Substituerede 1,2,3,4-tetrahydronapthalenderivater - Google Patents

Substituerede 1,2,3,4-tetrahydronapthalenderivater

Info

Publication number: DK1000048T3
Authority: DK; Denmark
Prior art keywords: tetrahydronaphthalane; derivatives; substituted; tetrahydronaphthalane derivatives
Prior art date: 1997-07-25

Application number

DK98934104T

Other languages

English (en)

Inventor

Stefan Berg

Mats Linderberg

Svante Ross

Seth-Olov Thorberg

Bengt Ulff

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-25

Filing date

1998-07-15

Publication date

2003-03-03

1998-07-15 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2003-03-03 Application granted granted Critical

2003-03-03 Publication of DK1000048T3 publication Critical patent/DK1000048T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Obesity (AREA)
Gynecology & Obstetrics (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Addiction (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK98934104T 1997-07-25 1998-07-15 Substituerede 1,2,3,4-tetrahydronapthalenderivater DK1000048T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9702799A SE9702799D0 (sv)	1997-07-25	1997-07-25	New compounds
PCT/SE1998/001390 WO1999005134A1 (en)	1997-07-25	1998-07-15	Substituted 1,2,3,4-tetrahydronaphthalene derivatives

Publications (1)

Publication Number	Publication Date
DK1000048T3 true DK1000048T3 (da)	2003-03-03

Family

ID=20407828

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98934104T DK1000048T3 (da)	1997-07-25	1998-07-15	Substituerede 1,2,3,4-tetrahydronapthalenderivater

Country Status (37)

Country	Link
US (3)	US6313118B1 (da)
EP (1)	EP1000048B1 (da)
JP (1)	JP3895923B2 (da)
KR (1)	KR20010022171A (da)
CN (1)	CN1270585A (da)
AR (2)	AR013370A1 (da)
AT (1)	ATE228510T1 (da)
AU (1)	AU739569B2 (da)
BR (1)	BR9811042A (da)
CA (1)	CA2296518A1 (da)
DE (1)	DE69809755T2 (da)
DK (1)	DK1000048T3 (da)
DZ (1)	DZ2569A1 (da)
EE (1)	EE04238B1 (da)
ES (1)	ES2187983T3 (da)
HK (1)	HK1025963A1 (da)
HR (1)	HRP980404B1 (da)
HU (1)	HUP0004334A3 (da)
ID (1)	ID24583A (da)
IL (1)	IL134108A0 (da)
IS (1)	IS5358A (da)
MA (1)	MA26521A1 (da)
NO (1)	NO315609B1 (da)
NZ (1)	NZ502384A (da)
PL (1)	PL338563A1 (da)
PT (1)	PT1000048E (da)
RU (1)	RU2194696C2 (da)
SE (1)	SE9702799D0 (da)
SI (1)	SI1000048T1 (da)
SK (1)	SK283918B6 (da)
TN (1)	TNSN98141A1 (da)
TR (1)	TR200000229T2 (da)
TW (1)	TW438781B (da)
UA (1)	UA69389C2 (da)
WO (1)	WO1999005134A1 (da)
YU (1)	YU2300A (da)
ZA (1)	ZA986588B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9601110D0 (sv)	1996-03-22	1996-03-22	Astra Ab	Substituted 1,2,3,4-tetrahydronaphthalene derivatives
SE9900190D0 (sv) *	1999-01-22	1999-01-22	Astra Ab	New compounds
SE9904724D0 (sv) *	1999-12-22	1999-12-22	Carlsson A Research Ab	New modulators of dopamine neurotransmission I
SE0002729D0 (sv) *	2000-07-20	2000-07-20	Astrazeneca Ab	Novel compound form
AR034206A1 (es) *	2001-02-16	2004-02-04	Solvay Pharm Bv	Un procedimiento para la preparacion de mesilatos de derivados de piperazina y dichos mesilatos
SE0102856D0 (sv) *	2001-08-27	2001-08-27	Astrazeneca Ab	A new method
SE0103644D0 (sv) *	2001-11-01	2001-11-01	Astrazeneca Ab	Therapeutic isoquinoline compounds
US7101881B2 (en) *	2003-06-11	2006-09-05	Pfizer Inc	Tetrahydroquinolines
SE0301798D0 (sv) *	2003-06-19	2003-06-19	Astrazeneca Ab	New use IV
SE0301794D0 (sv) *	2003-06-19	2003-06-19	Astrazeneca Ab	New use III
WO2005113527A1 (en) *	2004-05-21	2005-12-01	Pfizer Products Inc.	Tetrahydronaphthyl- piperazines as 5-ht1b antagonists, inverse agonists and partial agonists
US20080033050A1 (en) *	2006-08-04	2008-02-07	Richards Patricia Allison Tewe	Method of treating thermoregulatory disfunction with paroxetine
WO2008130321A2 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel n-tetrahydronaphtalene or 5-heterocyclyl-chromane or 8-heterocyclyl-tetrahydronaphtalene derivatives for the treatment of pain
WO2008130319A2 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel n-tetrahydronaphtalene or n-chromane carboxamide derivatives for the treatment of pain
SA08290245B1 (ar)	2007-04-23	2012-02-12	استرازينيكا ايه بي	مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم
WO2008130323A1 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel 8-piperazine-tetrahydronaphtalene derivatives for the treatment of pain
WO2008130322A1 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel 5-heterocyclyl-chromane derivatives for the treatment of pain
EP2098511A1 (en)	2008-03-07	2009-09-09	Solvias AG	Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring
MY157518A (en)	2008-06-20	2016-06-15	Astrazeneca Ab	Dibenzothiazepine derivatives and use thereof
GB201002563D0 (en)	2010-02-15	2010-03-31	Cambridge Entpr Ltd	Compounds
GB201111705D0 (en)	2011-07-07	2011-08-24	Takeda Pharmaceutical	Compounds and their use
GB201111704D0 (en)	2011-07-07	2011-08-24	Takeda Pharmaceutical	Novel compounds
JO3115B1 (ar)	2011-08-22	2017-09-20	Takeda Pharmaceuticals Co	مركبات بيريدازينون واستخدامها كمثبطات daao
GB201209587D0 (en)	2012-05-30	2012-07-11	Takeda Pharmaceutical	Therapeutic compounds
WO2014202999A1 (en)	2013-06-21	2014-12-24	Takeda Cambridge Limited	1-sulfonyl piperidine derivatives as modulators of prokineticin receptors
GB201314286D0 (en)	2013-08-08	2013-09-25	Takeda Pharmaceutical	Therapeutic Compounds
GB201318222D0 (en)	2013-10-15	2013-11-27	Takeda Pharmaceutical	Novel compounds
GB201320905D0 (en)	2013-11-27	2014-01-08	Takeda Pharmaceutical	Therapeutic compounds
TW201613864A (en)	2014-02-20	2016-04-16	Takeda Pharmaceutical	Novel compounds
GB201616839D0 (en)	2016-10-04	2016-11-16	Takeda Pharmaceutical Company Limited	Therapeutic compounds
GB201619514D0 (en)	2016-11-18	2017-01-04	Takeda Pharmaceuticals Co	Novel compounds
JP2021138648A (ja)	2020-03-04	2021-09-16	武田薬品工業株式会社	経口固形製剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3919624A1 (de)	1989-06-15	1990-12-20	Boehringer Ingelheim Kg	Neue 2,5-diaminotetraline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB9119932D0 (en)	1991-09-18	1991-10-30	Glaxo Group Ltd	Chemical compounds
GB9119920D0 (en)	1991-09-18	1991-10-30	Glaxo Group Ltd	Chemical compounds
ES2162792T3 (es)	1991-09-18	2002-01-16	Glaxo Group Ltd	Derivados de benzanilida como antagonistas de 5-ht1d.
DK148392D0 (da)	1992-12-09	1992-12-09	Lundbeck & Co As H	Heterocykliske forbindelser
GB2273930A (en)	1992-12-30	1994-07-06	Glaxo Group Ltd	Benzanilide derivatives
CA2158457C (en)	1993-03-16	2001-04-17	Bertrand Leo Chenard	Naphthalene derivatives
JPH09503773A (ja)	1993-10-19	1997-04-15	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	５ｈｔ−１ｄレセプター拮抗剤用のベンズアニリド誘導体
SE9601110D0 (sv) *	1996-03-22	1996-03-22	Astra Ab	Substituted 1,2,3,4-tetrahydronaphthalene derivatives

1997
- 1997-07-25 SE SE9702799A patent/SE9702799D0/xx unknown
1998
- 1998-07-13 TW TW087111330A patent/TW438781B/zh not_active IP Right Cessation
- 1998-07-15 CA CA002296518A patent/CA2296518A1/en not_active Abandoned
- 1998-07-15 AT AT98934104T patent/ATE228510T1/de not_active IP Right Cessation
- 1998-07-15 WO PCT/SE1998/001390 patent/WO1999005134A1/en not_active Application Discontinuation
- 1998-07-15 DK DK98934104T patent/DK1000048T3/da active
- 1998-07-15 HU HU0004334A patent/HUP0004334A3/hu unknown
- 1998-07-15 EP EP98934104A patent/EP1000048B1/en not_active Expired - Lifetime
- 1998-07-15 SK SK1883-99A patent/SK283918B6/sk unknown
- 1998-07-15 BR BR9811042-0A patent/BR9811042A/pt not_active IP Right Cessation
- 1998-07-15 YU YU2300A patent/YU2300A/sh unknown
- 1998-07-15 ID IDW20000122A patent/ID24583A/id unknown
- 1998-07-15 UA UA2000021064A patent/UA69389C2/uk unknown
- 1998-07-15 ES ES98934104T patent/ES2187983T3/es not_active Expired - Lifetime
- 1998-07-15 EE EEP200000041A patent/EE04238B1/xx not_active IP Right Cessation
- 1998-07-15 SI SI9830343T patent/SI1000048T1/xx unknown
- 1998-07-15 DE DE69809755T patent/DE69809755T2/de not_active Expired - Fee Related
- 1998-07-15 US US09/171,577 patent/US6313118B1/en not_active Expired - Fee Related
- 1998-07-15 CN CN98809246A patent/CN1270585A/zh active Pending
- 1998-07-15 PT PT98934104T patent/PT1000048E/pt unknown
- 1998-07-15 KR KR1020007000743A patent/KR20010022171A/ko not_active Application Discontinuation
- 1998-07-15 RU RU2000104802/04A patent/RU2194696C2/ru not_active IP Right Cessation
- 1998-07-15 IL IL13410898A patent/IL134108A0/xx unknown
- 1998-07-15 MA MA25169A patent/MA26521A1/fr unknown
- 1998-07-15 TR TR2000/00229T patent/TR200000229T2/xx unknown
- 1998-07-15 AU AU83703/98A patent/AU739569B2/en not_active Ceased
- 1998-07-15 JP JP2000504131A patent/JP3895923B2/ja not_active Expired - Fee Related
- 1998-07-15 PL PL98338563A patent/PL338563A1/xx unknown
- 1998-07-15 NZ NZ502384A patent/NZ502384A/en unknown
- 1998-07-22 DZ DZ980179A patent/DZ2569A1/xx active
- 1998-07-23 HR HR980404A patent/HRP980404B1/xx not_active IP Right Cessation
- 1998-07-23 TN TNTNSN98141A patent/TNSN98141A1/fr unknown
- 1998-07-23 ZA ZA986588A patent/ZA986588B/xx unknown
- 1998-07-24 AR ARP980103667A patent/AR013370A1/es unknown
2000
- 2000-01-24 IS IS5358A patent/IS5358A/is unknown
- 2000-01-24 NO NO20000356A patent/NO315609B1/no not_active IP Right Cessation
- 2000-08-17 HK HK00105178A patent/HK1025963A1/xx not_active IP Right Cessation
2001
- 2001-07-10 US US09/902,123 patent/US6534652B2/en not_active Expired - Fee Related
- 2001-07-10 US US09/902,000 patent/US6410532B2/en not_active Expired - Fee Related
2004
- 2004-10-25 AR ARP040103875A patent/AR046193A2/es unknown

Also Published As

Publication number	Publication date
DE69809755T2 (de)	2003-07-17
US20010051623A1 (en)	2001-12-13
AU739569B2 (en)	2001-10-18
HRP980404A2 (en)	1999-04-30
CA2296518A1 (en)	1999-02-04
YU2300A (sh)	2002-10-18
IL134108A0 (en)	2001-04-30
TR200000229T2 (tr)	2000-06-21
TW438781B (en)	2001-06-07
AR046193A2 (es)	2005-11-30
US6534652B2 (en)	2003-03-18
TNSN98141A1 (fr)	2005-03-15
SI1000048T1 (en)	2003-04-30
ID24583A (id)	2000-07-27
EP1000048B1 (en)	2002-11-27
BR9811042A (pt)	2000-08-15
EP1000048A1 (en)	2000-05-17
PT1000048E (pt)	2003-03-31
MA26521A1 (fr)	2004-12-20
SK188399A3 (en)	2000-07-11
NO20000356L (no)	2000-03-27
HK1025963A1 (en)	2000-12-01
ES2187983T3 (es)	2003-06-16
SE9702799D0 (sv)	1997-07-25
AR013370A1 (es)	2000-12-27
EE04238B1 (et)	2004-02-16
ATE228510T1 (de)	2002-12-15
KR20010022171A (ko)	2001-03-15
JP3895923B2 (ja)	2007-03-22
EE200000041A (et)	2000-10-16
ZA986588B (en)	1999-01-25
IS5358A (is)	2000-01-24
SK283918B6 (sk)	2004-05-04
DZ2569A1 (fr)	2003-02-15
PL338563A1 (en)	2000-11-06
RU2194696C2 (ru)	2002-12-20
DE69809755D1 (de)	2003-01-09
AU8370398A (en)	1999-02-16
HUP0004334A2 (en)	2001-03-28
WO1999005134A1 (en)	1999-02-04
NO20000356D0 (no)	2000-01-24
UA69389C2 (uk)	2004-09-15
HRP980404B1 (en)	2002-10-31
HUP0004334A3 (en)	2002-10-28
US20010051626A1 (en)	2001-12-13
US6313118B1 (en)	2001-11-06
NO315609B1 (no)	2003-09-29
JP2001510837A (ja)	2001-08-07
US6410532B2 (en)	2002-06-25
NZ502384A (en)	2001-05-25
CN1270585A (zh)	2000-10-18

Publication	Publication Date	Title
DE69736711D1 (de)	2006-11-02	Substituierte 6,5-heterobicyclische-derivate
DK0925298T3 (da)	2004-08-09	Substituerede 6,6-heterobicykliske derivater
DK1000048T3 (da)	2003-03-03	Substituerede 1,2,3,4-tetrahydronapthalenderivater
ATE435861T1 (de)	2009-07-15	12,13-cyclopropan-epothilonderivate
NO2006016I1 (no)	2006-11-27	7,8,9,10-tetrahydro-6H-6,10-metanoazepinoÄ4,5-gÜkinoksalintartrat
PT993456E (pt)	2005-01-31	4,5-diaril-imidazoles 2-substituidos
NL300150I2 (nl)	2004-09-01	4 "-Gesubstitueerde 9-deoxo-9A-AZA-9A-homoërythromycine-A-derivaten.
DE69718771D1 (de)	2003-03-06	Substituierte 1,2,3,4-tetrahydronaphthalinderivate
ATE255098T1 (de)	2003-12-15	Substituierte chromanderivate
ATE257484T1 (de)	2004-01-15	6,9-verbrückte erythromycin-derivate
PT921125E (pt)	2002-06-28	Derivados de 1,38-triaza-espiro 4,5 decan-4-ona
ATE239750T1 (de)	2003-05-15	6,11-verbrückte erythromycinderivate
DK0922050T3 (da)	2003-11-24	3-Descladinose-2,3-anhydroerythromycin-derivater
TR199800988A3 (tr)	1998-12-21	5' Deoksi-Sitidin türevleri.
ATE255099T1 (de)	2003-12-15	Substituierte chromanderivate
ATE227282T1 (de)	2002-11-15	2,4-diaminopyrimidin-derivate
NO20003825D0 (no)	2000-07-26	1,3,4 - oxadiazolonderivater
DK1068200T3 (da)	2005-06-20	2,4,4-trisubstituerede-1,3-dioxolanfungicider
ID24047A (id)	2000-07-06	Turunan 5-tersubstitusi-3-oksaziazolil 1,6-naftiridin-2 1h-on
DE69722064D1 (de)	2003-06-26	1,25-Dihydroxy-16,22,23-trisdehydro-Cholecalciferol-Derivate