ATE227282T1 - 2,4-diaminopyrimidin-derivate - Google Patents
2,4-diaminopyrimidin-derivateInfo
- Publication number
- ATE227282T1 ATE227282T1 AT97923018T AT97923018T ATE227282T1 AT E227282 T1 ATE227282 T1 AT E227282T1 AT 97923018 T AT97923018 T AT 97923018T AT 97923018 T AT97923018 T AT 97923018T AT E227282 T1 ATE227282 T1 AT E227282T1
- Authority
- AT
- Austria
- Prior art keywords
- diaminopyrimidine derivatives
- diaminopyrimidine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96107739 | 1996-05-15 | ||
PCT/EP1997/002355 WO1997043277A1 (en) | 1996-05-15 | 1997-05-07 | 2,4-diaminopyrimidine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE227282T1 true ATE227282T1 (de) | 2002-11-15 |
Family
ID=8222784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97923018T ATE227282T1 (de) | 1996-05-15 | 1997-05-07 | 2,4-diaminopyrimidin-derivate |
Country Status (29)
Country | Link |
---|---|
US (1) | US5866583A (de) |
EP (1) | EP0901488B1 (de) |
JP (1) | JP3098259B2 (de) |
KR (1) | KR100295509B1 (de) |
CN (1) | CN1098260C (de) |
AR (1) | AR007088A1 (de) |
AT (1) | ATE227282T1 (de) |
AU (1) | AU726416B2 (de) |
BR (1) | BR9709251A (de) |
CA (1) | CA2254117C (de) |
CO (1) | CO4840509A1 (de) |
CY (1) | CY2425B1 (de) |
CZ (1) | CZ364698A3 (de) |
DE (1) | DE69716901T2 (de) |
DK (1) | DK0901488T3 (de) |
ES (1) | ES2184089T3 (de) |
HR (1) | HRP970260A2 (de) |
IL (1) | IL126702A0 (de) |
MA (1) | MA24182A1 (de) |
NO (1) | NO985335L (de) |
NZ (1) | NZ332481A (de) |
PE (1) | PE78898A1 (de) |
PL (1) | PL330277A1 (de) |
PT (1) | PT901488E (de) |
TR (1) | TR199802331T2 (de) |
TW (1) | TW438796B (de) |
WO (1) | WO1997043277A1 (de) |
YU (1) | YU51498A (de) |
ZA (1) | ZA973984B (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0966464B1 (de) * | 1997-03-03 | 2003-05-28 | Basilea Pharmaceutica AG | Substituierte 2,4-diaminopyrimidine |
ES2198705T3 (es) * | 1997-03-03 | 2004-02-01 | Basilea Pharmaceutica Ag | 2,4-diaminopiridinas sustituidas. |
US6277860B1 (en) * | 1999-10-29 | 2001-08-21 | Pfizer Inc | Furopyridine antibacterials |
US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
AU2004260636A1 (en) * | 2003-06-13 | 2005-02-10 | Arena Pharmaceuticals, Inc. | 5-substituted 2H-pyrazole-3-carboxylic acid derivatives as agonists for the nicotinic acid receptor RUP25 for the treatment of dyslipidemia and related diseases |
JP2007501789A (ja) * | 2003-08-07 | 2007-02-01 | メルク エンド カムパニー インコーポレーテッド | 11−β−ヒドロキシステロイドデヒドロゲナーゼ−1の阻害剤としてのピラゾールカルボキサミド |
WO2005016278A2 (en) | 2003-08-12 | 2005-02-24 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
DE102005062987A1 (de) * | 2005-12-28 | 2007-07-05 | Grünenthal GmbH | Substituierte Propiolsäureamide und ihre Verwendung zur Herstellung von Arzneimitteln |
AU2008285795A1 (en) * | 2007-08-03 | 2009-02-12 | F. Hoffmann-La Roche Ag | Pyridinecarboxamide and benzamide derivatives as TAAR1 ligands |
US8252790B2 (en) * | 2008-11-21 | 2012-08-28 | Raqualia Pharma Inc. | Pyrazole-3-carboxamide derivative having 5-HT2B receptor antagonist activity |
EP2389376A1 (de) * | 2009-01-21 | 2011-11-30 | Basilea Pharmaceutica AG | Neue bicyclische antibiotika |
CN102753531B (zh) * | 2009-12-15 | 2015-07-01 | 拜尔农作物科学股份公司 | 制备1-烷基-/1-芳基-5-吡唑羧酸衍生物的方法 |
EA201391239A1 (ru) | 2011-04-05 | 2014-03-31 | Пфайзер Лимитед | Пирроло[2,3-d]пиримидиновые производные в качестве ингибиторов тропомиозин-связанных киназ |
DE102013208484B4 (de) | 2013-05-08 | 2018-04-26 | Wirtgen Gmbh | Vorrichtung zum Bearbeiten von Straßen- oder Bodenoberflächen, sowie Verfahren zum Lenken einer Straßenfräsmaschine |
WO2020041556A1 (en) * | 2018-08-22 | 2020-02-27 | The Regents Of The University Of Colorado, A Body Corporate | N-substituted-1h-1,2,4-triazole-3-carboxamides, analogues thereof, and methods of treatment using same |
AR117169A1 (es) * | 2018-11-28 | 2021-07-14 | Bayer Ag | (tio)amidas de piridazina como compuestos fungicidas |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3485840A (en) * | 1964-11-12 | 1969-12-23 | Hoffmann La Roche | 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes |
US4515948A (en) * | 1973-09-12 | 1985-05-07 | Hoffmann-La Roche Inc. | 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines |
US4013644A (en) * | 1976-03-15 | 1977-03-22 | G. D. Searle & Co. | [8 α(E), 13aβ]-5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-8-(2-phenylethenyl)-6H-dibenzo[a,g]quinolizines and intermediates thereto |
US4444770A (en) * | 1980-05-29 | 1984-04-24 | Bayer Aktiengesellschaft | New imidazoazole-alkenoic acid amide compounds, intermediate products for their production, their production, and their medicinal use |
US4594199A (en) * | 1983-09-19 | 1986-06-10 | E. R. Squibb & Sons, Inc. | Method for making phosphinic acid intermediates |
EP0639075A1 (de) * | 1990-11-14 | 1995-02-22 | Chiron Corporation | Spezifische hemmung der dihydrofolsäurereduktase und wirkstoffe dafür |
BR9509768A (pt) * | 1994-11-24 | 1998-07-07 | Hoffmann La Roche | Novas pirimidinas de benzila |
EP0832069B1 (de) * | 1995-06-07 | 2003-03-05 | Pfizer Inc. | Biphenyl-2-carbonsäure-tetrahydro-isochinolin-6-yl amid derivate, deren hestellung und deren verwendung als inhibitoren des mikrosomalen triglycerid-transfer-proteins und/oder der apolipoprotein b (apo b) sekretion |
EP1149834A1 (de) * | 1995-12-04 | 2001-10-31 | F. Hoffmann-La Roche Ag | Diaminopyrimidine, diese enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung als antibakterielle Mittel |
-
1997
- 1997-04-19 TW TW086105103A patent/TW438796B/zh active
- 1997-04-24 US US08/842,459 patent/US5866583A/en not_active Expired - Lifetime
- 1997-05-07 CN CN97194633A patent/CN1098260C/zh not_active Expired - Fee Related
- 1997-05-07 DK DK97923018T patent/DK0901488T3/da active
- 1997-05-07 CZ CZ983646A patent/CZ364698A3/cs unknown
- 1997-05-07 EP EP97923018A patent/EP0901488B1/de not_active Expired - Lifetime
- 1997-05-07 ES ES97923018T patent/ES2184089T3/es not_active Expired - Lifetime
- 1997-05-07 TR TR1998/02331T patent/TR199802331T2/xx unknown
- 1997-05-07 CA CA002254117A patent/CA2254117C/en not_active Expired - Fee Related
- 1997-05-07 AU AU28942/97A patent/AU726416B2/en not_active Ceased
- 1997-05-07 DE DE69716901T patent/DE69716901T2/de not_active Expired - Lifetime
- 1997-05-07 JP JP09540486A patent/JP3098259B2/ja not_active Expired - Fee Related
- 1997-05-07 AT AT97923018T patent/ATE227282T1/de not_active IP Right Cessation
- 1997-05-07 NZ NZ332481A patent/NZ332481A/xx unknown
- 1997-05-07 PT PT97923018T patent/PT901488E/pt unknown
- 1997-05-07 PL PL97330277A patent/PL330277A1/xx unknown
- 1997-05-07 IL IL12670297A patent/IL126702A0/xx unknown
- 1997-05-07 KR KR1019980709204A patent/KR100295509B1/ko not_active IP Right Cessation
- 1997-05-07 BR BR9709251A patent/BR9709251A/pt not_active IP Right Cessation
- 1997-05-07 PE PE1997000356A patent/PE78898A1/es not_active Application Discontinuation
- 1997-05-07 WO PCT/EP1997/002355 patent/WO1997043277A1/en active IP Right Grant
- 1997-05-08 ZA ZA9703984A patent/ZA973984B/xx unknown
- 1997-05-12 AR ARP970101966A patent/AR007088A1/es unknown
- 1997-05-14 CO CO97025823A patent/CO4840509A1/es unknown
- 1997-05-15 MA MA24620A patent/MA24182A1/fr unknown
- 1997-05-15 HR HR96107739.3A patent/HRP970260A2/xx not_active Application Discontinuation
-
1998
- 1998-11-13 YU YU51498A patent/YU51498A/sr unknown
- 1998-11-16 NO NO985335A patent/NO985335L/no not_active Application Discontinuation
-
2004
- 2004-02-20 CY CY0400011A patent/CY2425B1/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0901488 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |