YU2300A - Derivati supstituisanog 1,2,3,4-tetrahidronaftalina - Google Patents
Derivati supstituisanog 1,2,3,4-tetrahidronaftalinaInfo
- Publication number
- YU2300A YU2300A YU2300A YU2300A YU2300A YU 2300 A YU2300 A YU 2300A YU 2300 A YU2300 A YU 2300A YU 2300 A YU2300 A YU 2300A YU 2300 A YU2300 A YU 2300A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- alkyl
- substituted
- cycloalkyl
- enantiomers
- alkoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Ovaj pronalazak se odnosi na nove piperidil-ili piperazinil- supstituisane derivate 1,2,3,4-tetrahidronaftalina, koji imaju formulu I u kojoj su X je N ili CH, Y je NR2CH2, CH2-NR2, NR2-CO, CO-NR2 ili NR2SO2, gde R2 predstavlja H ili C1-C6 alkil; R1 je H, C1-C6 alkil ili C3-C6 cikloalkil; R3 je C1-C6 alkil, C3-C6 cikloalkil ili (CH2)n-aril, gde aril predstavlja fenil ili heteroaromaticni prsten koji sadrzi jedan ili dva heteroatoma koji se biraju izmedju, N, O i S, a koji mogu biti mono- ili di- supstituisani n je 0-4; R9 je C1-C6 alkil, C3-C6 cikloalkil, OCF3, OCHF2, OCH2F, halogen, CN, CF3, OH, C1-C6 alkoksi,, C1-C6 alkoksi- C1-C6 alkil, Nr6R7, SO3CH3, SO3CF3, SO2NR6R7, nesupstituisani ili supstituisani heterociklicni ili heteroaromaticni prsten koji sadrzi jedan ili dva heteroatoma koji se biraju izmedju N i O, a supstituenti(i) je(su) C1-C6 alkil; ili COR8; gde su R6, R7 i R8 ranije definisani, kao (R)-enentiomeri, (S)-enantiomeri ili racemati u obliku slobodne baze ili njenih farmaceutski prihvatljivih soli ili solvata, na postupke njihovog dobijanja, farmaceutske preparate koji sadrze pomenuta terapeutski aktivna jedinjenja i na upotrebu pomenutih aktivnih jedinjenja u lecenju.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9702799A SE9702799D0 (sv) | 1997-07-25 | 1997-07-25 | New compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU2300A true YU2300A (sh) | 2002-10-18 |
Family
ID=20407828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU2300A YU2300A (sh) | 1997-07-25 | 1998-07-15 | Derivati supstituisanog 1,2,3,4-tetrahidronaftalina |
Country Status (37)
| Country | Link |
|---|---|
| US (3) | US6313118B1 (sh) |
| EP (1) | EP1000048B1 (sh) |
| JP (1) | JP3895923B2 (sh) |
| KR (1) | KR20010022171A (sh) |
| CN (1) | CN1270585A (sh) |
| AR (2) | AR013370A1 (sh) |
| AT (1) | ATE228510T1 (sh) |
| AU (1) | AU739569B2 (sh) |
| BR (1) | BR9811042A (sh) |
| CA (1) | CA2296518A1 (sh) |
| DE (1) | DE69809755T2 (sh) |
| DK (1) | DK1000048T3 (sh) |
| DZ (1) | DZ2569A1 (sh) |
| EE (1) | EE04238B1 (sh) |
| ES (1) | ES2187983T3 (sh) |
| HK (1) | HK1025963A1 (sh) |
| HR (1) | HRP980404B1 (sh) |
| HU (1) | HUP0004334A3 (sh) |
| ID (1) | ID24583A (sh) |
| IL (1) | IL134108A0 (sh) |
| IS (1) | IS5358A (sh) |
| MA (1) | MA26521A1 (sh) |
| NO (1) | NO315609B1 (sh) |
| NZ (1) | NZ502384A (sh) |
| PL (1) | PL338563A1 (sh) |
| PT (1) | PT1000048E (sh) |
| RU (1) | RU2194696C2 (sh) |
| SE (1) | SE9702799D0 (sh) |
| SI (1) | SI1000048T1 (sh) |
| SK (1) | SK283918B6 (sh) |
| TN (1) | TNSN98141A1 (sh) |
| TR (1) | TR200000229T2 (sh) |
| TW (1) | TW438781B (sh) |
| UA (1) | UA69389C2 (sh) |
| WO (1) | WO1999005134A1 (sh) |
| YU (1) | YU2300A (sh) |
| ZA (1) | ZA986588B (sh) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9601110D0 (sv) * | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
| SE9900190D0 (sv) * | 1999-01-22 | 1999-01-22 | Astra Ab | New compounds |
| SE9904724D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| SE0002729D0 (sv) | 2000-07-20 | 2000-07-20 | Astrazeneca Ab | Novel compound form |
| AR034206A1 (es) * | 2001-02-16 | 2004-02-04 | Solvay Pharm Bv | Un procedimiento para la preparacion de mesilatos de derivados de piperazina y dichos mesilatos |
| SE0102856D0 (sv) * | 2001-08-27 | 2001-08-27 | Astrazeneca Ab | A new method |
| SE0103644D0 (sv) * | 2001-11-01 | 2001-11-01 | Astrazeneca Ab | Therapeutic isoquinoline compounds |
| US7101881B2 (en) * | 2003-06-11 | 2006-09-05 | Pfizer Inc | Tetrahydroquinolines |
| SE0301798D0 (sv) * | 2003-06-19 | 2003-06-19 | Astrazeneca Ab | New use IV |
| SE0301794D0 (sv) * | 2003-06-19 | 2003-06-19 | Astrazeneca Ab | New use III |
| CA2566934A1 (en) * | 2004-05-21 | 2005-12-01 | Pfizer Products Inc. | Tetrahydronaphthyl- piperazines as 5-ht1b antagonists, inverse agonists and partial agonists |
| US20080033050A1 (en) * | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
| WO2008130321A2 (en) * | 2007-04-23 | 2008-10-30 | Astrazeneca Ab | Novel n-tetrahydronaphtalene or 5-heterocyclyl-chromane or 8-heterocyclyl-tetrahydronaphtalene derivatives for the treatment of pain |
| WO2008130323A1 (en) * | 2007-04-23 | 2008-10-30 | Astrazeneca Ab | Novel 8-piperazine-tetrahydronaphtalene derivatives for the treatment of pain |
| WO2008130319A2 (en) * | 2007-04-23 | 2008-10-30 | Astrazeneca Ab | Novel n-tetrahydronaphtalene or n-chromane carboxamide derivatives for the treatment of pain |
| SA08290245B1 (ar) * | 2007-04-23 | 2012-02-12 | استرازينيكا ايه بي | مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم |
| WO2008130322A1 (en) * | 2007-04-23 | 2008-10-30 | Astrazeneca Ab | Novel 5-heterocyclyl-chromane derivatives for the treatment of pain |
| EP2098511A1 (en) | 2008-03-07 | 2009-09-09 | Solvias AG | Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring |
| MY157518A (en) | 2008-06-20 | 2016-06-15 | Astrazeneca Ab | Dibenzothiazepine derivatives and use thereof |
| GB201002563D0 (en) | 2010-02-15 | 2010-03-31 | Cambridge Entpr Ltd | Compounds |
| GB201111704D0 (en) | 2011-07-07 | 2011-08-24 | Takeda Pharmaceutical | Novel compounds |
| GB201111705D0 (en) | 2011-07-07 | 2011-08-24 | Takeda Pharmaceutical | Compounds and their use |
| JO3115B1 (ar) | 2011-08-22 | 2017-09-20 | Takeda Pharmaceuticals Co | مركبات بيريدازينون واستخدامها كمثبطات daao |
| GB201209587D0 (en) | 2012-05-30 | 2012-07-11 | Takeda Pharmaceutical | Therapeutic compounds |
| CN105324372B (zh) | 2013-06-21 | 2018-03-06 | 武田药品工业株式会社 | 作为前动力蛋白受体调节剂的1‑磺酰基哌啶衍生物 |
| GB201314286D0 (en) | 2013-08-08 | 2013-09-25 | Takeda Pharmaceutical | Therapeutic Compounds |
| GB201318222D0 (en) | 2013-10-15 | 2013-11-27 | Takeda Pharmaceutical | Novel compounds |
| GB201320905D0 (en) | 2013-11-27 | 2014-01-08 | Takeda Pharmaceutical | Therapeutic compounds |
| TW201613864A (en) | 2014-02-20 | 2016-04-16 | Takeda Pharmaceutical | Novel compounds |
| GB201616839D0 (en) | 2016-10-04 | 2016-11-16 | Takeda Pharmaceutical Company Limited | Therapeutic compounds |
| GB201619514D0 (en) | 2016-11-18 | 2017-01-04 | Takeda Pharmaceuticals Co | Novel compounds |
| JP2021138648A (ja) | 2020-03-04 | 2021-09-16 | 武田薬品工業株式会社 | 経口固形製剤 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3919624A1 (de) | 1989-06-15 | 1990-12-20 | Boehringer Ingelheim Kg | Neue 2,5-diaminotetraline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| GB9119920D0 (en) | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
| GB9119932D0 (en) | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
| EP0533268B1 (en) | 1991-09-18 | 2001-08-16 | Glaxo Group Limited | Benzanilide derivatives as 5-HT1D antagonists |
| DK148392D0 (da) | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Heterocykliske forbindelser |
| GB2273930A (en) | 1992-12-30 | 1994-07-06 | Glaxo Group Ltd | Benzanilide derivatives |
| EP0689536B1 (en) | 1993-03-16 | 2001-05-23 | Pfizer Inc. | Naphthalene derivatives |
| WO1995011243A1 (en) | 1993-10-19 | 1995-04-27 | Smithkline Beecham Plc | Benzanilide derivatives as 5ht-1d receptor antagonists |
| SE9601110D0 (sv) | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
-
1997
- 1997-07-25 SE SE9702799A patent/SE9702799D0/xx unknown
-
1998
- 1998-07-13 TW TW087111330A patent/TW438781B/zh not_active IP Right Cessation
- 1998-07-15 YU YU2300A patent/YU2300A/sh unknown
- 1998-07-15 HU HU0004334A patent/HUP0004334A3/hu unknown
- 1998-07-15 EP EP98934104A patent/EP1000048B1/en not_active Expired - Lifetime
- 1998-07-15 US US09/171,577 patent/US6313118B1/en not_active Expired - Fee Related
- 1998-07-15 DK DK98934104T patent/DK1000048T3/da active
- 1998-07-15 PT PT98934104T patent/PT1000048E/pt unknown
- 1998-07-15 AU AU83703/98A patent/AU739569B2/en not_active Ceased
- 1998-07-15 TR TR2000/00229T patent/TR200000229T2/xx unknown
- 1998-07-15 WO PCT/SE1998/001390 patent/WO1999005134A1/en not_active Application Discontinuation
- 1998-07-15 PL PL98338563A patent/PL338563A1/xx unknown
- 1998-07-15 CA CA002296518A patent/CA2296518A1/en not_active Abandoned
- 1998-07-15 SK SK1883-99A patent/SK283918B6/sk unknown
- 1998-07-15 SI SI9830343T patent/SI1000048T1/xx unknown
- 1998-07-15 BR BR9811042-0A patent/BR9811042A/pt not_active IP Right Cessation
- 1998-07-15 KR KR1020007000743A patent/KR20010022171A/ko not_active Application Discontinuation
- 1998-07-15 MA MA25169A patent/MA26521A1/fr unknown
- 1998-07-15 ID IDW20000122A patent/ID24583A/id unknown
- 1998-07-15 RU RU2000104802/04A patent/RU2194696C2/ru not_active IP Right Cessation
- 1998-07-15 EE EEP200000041A patent/EE04238B1/xx not_active IP Right Cessation
- 1998-07-15 NZ NZ502384A patent/NZ502384A/en unknown
- 1998-07-15 CN CN98809246A patent/CN1270585A/zh active Pending
- 1998-07-15 UA UA2000021064A patent/UA69389C2/uk unknown
- 1998-07-15 AT AT98934104T patent/ATE228510T1/de not_active IP Right Cessation
- 1998-07-15 JP JP2000504131A patent/JP3895923B2/ja not_active Expired - Fee Related
- 1998-07-15 ES ES98934104T patent/ES2187983T3/es not_active Expired - Lifetime
- 1998-07-15 IL IL13410898A patent/IL134108A0/xx unknown
- 1998-07-15 DE DE69809755T patent/DE69809755T2/de not_active Expired - Fee Related
- 1998-07-22 DZ DZ980179A patent/DZ2569A1/xx active
- 1998-07-23 ZA ZA986588A patent/ZA986588B/xx unknown
- 1998-07-23 HR HR980404A patent/HRP980404B1/xx not_active IP Right Cessation
- 1998-07-23 TN TNTNSN98141A patent/TNSN98141A1/fr unknown
- 1998-07-24 AR ARP980103667A patent/AR013370A1/es unknown
-
2000
- 2000-01-24 NO NO20000356A patent/NO315609B1/no not_active IP Right Cessation
- 2000-01-24 IS IS5358A patent/IS5358A/is unknown
- 2000-08-17 HK HK00105178A patent/HK1025963A1/xx not_active IP Right Cessation
-
2001
- 2001-07-10 US US09/902,123 patent/US6534652B2/en not_active Expired - Fee Related
- 2001-07-10 US US09/902,000 patent/US6410532B2/en not_active Expired - Fee Related
-
2004
- 2004-10-25 AR ARP040103875A patent/AR046193A2/es unknown
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