DBP(유전자)

DBP
식별자
에일리어스	DBP, DABP, D박스 바인딩 PAR bZIP 전사율, taxREB302
외부 ID	OMIM: 124097 MGI: 94866 HomoloGene: 1035 GeneCard: DBP
유전자 위치(인간)
크르.	19번 염색체(인간)
끝.	48,637,379 bp
유전자 위치(마우스)
크르.	7번 염색체(쥐)
끝.	45,359,627 bp
RNA발현패턴
	상단 표시 위치:
	미산핵; ; 핵액컴벤스; ; 전전두피질; ; 창호; ; 대상회; ; 뇌하수체 전엽; ; 복부 피부; ; 브로드만 9구역; ; 편도체; ; 갑상선 좌엽;
	상단 표시 위치:
	망막 색소 상피; ; 홍채; ; 후결절; ; 발목; ; 핵액컴벤스; ; 눈물샘; ; 쇄골상핵; ; 흑색 실체; ; 내측 유전핵; ; 내측 배핵;
	추가 참조 표현식 데이터
	; ;
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	DNA결합전사인자활성; DNA결합; DNA결합전사활성화제, RNA중합효소II 특이적; RNA중합효소II전사조절영역배열특이적DNA결합; DNA결합전사인자활성, RNA중합효소II 특이적;
셀룰러 컴포넌트	핵;
생물학적 과정	RNA중합효소II에 의한 전사조절; 간발달성; 전사조절, DNA템플릿화; 전사, DNA 템플릿; RNA중합효소II에 의한 전사의 양성 조절; 율동 과정; 일주 리듬; 다세포 생물 발달; RNA중합효소II에 의한 전사;
	출처:아미고 / QuickGO
맞춤법
	1628
	13170
	ENSG00000105516
	ENSMUSG000059824
	문제 10586
	Q60925
	NM_001352
	NM_016974
	NP_001343
	NP_058670
	위키데이터
인간 보기/편집	마우스 표시/편집

DBP로도 알려진 알부민 프로모터(알부민 D-박스) 결합 단백질의 D 부위는 인체에서 DBP ^[5]^[6]유전자에 의해 암호화되는 단백질이다.

DBP는 PAR bZIP(프롤린 및 산성 아미노산 풍부 염기성 류신 ZIPper) 전사인자 패밀리의 ^[5]^[7]구성원입니다.DBP는 인슐린 ^[8]유전자의 상류 프로모터와 결합합니다.

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000105516 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000059824 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: DBP D site of albumin promoter (albumin D-box) binding protein".
^ Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (Jun 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics. 13 (2): 293–300. doi:10.1016/0888-7543(92)90245-N. PMID 1535333.
^ Khatib ZA, Inaba T, Valentine M, Look AT (Sep 1994). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes". Genomics. 23 (2): 344–51. doi:10.1006/geno.1994.1510. PMID 7835883.
^ Melloul D, Marshak S, Cerasi E (Mar 2002). "Regulation of insulin gene transcription". Diabetologia. 45 (3): 309–26. doi:10.1007/s00125-001-0728-y. PMID 11914736.

추가 정보

Brown SA, Schibler U (Oct 1999). "The ins and outs of circadian timekeeping". Current Opinion in Genetics & Development. 9 (5): 588–94. doi:10.1016/S0959-437X(99)00009-X. PMID 10508692.
Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (Jun 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics. 13 (2): 293–300. doi:10.1016/0888-7543(92)90245-N. PMID 1535333.
Khatib ZA, Inaba T, Valentine M, Look AT (Sep 1994). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes". Genomics. 23 (2): 344–51. doi:10.1006/geno.1994.1510. PMID 7835883.
Nyunoya H, Morita T, Sato T, Honma S, Tsujimoto A, Shimotohno K (Oct 1994). "Cloning of a cDNA encoding a DNA-binding protein TAXREB302 that is specific for the tax-responsive enhancer of HTLV-I". Gene. 148 (2): 371–3. doi:10.1016/0378-1119(94)90716-1. PMID 7958972.
Nyunoya H, Morita T, Sato T, Honma S, Tsujimoto A, Shimotohno K (Apr 1993). "Cloning of a cDNA encoding a DNA-binding protein TAXREB302 that is specific for the tax-responsive enhancer of HTLV-I". Gene. 126 (2): 251–5. doi:10.1016/0378-1119(93)90375-D. PMID 8482542.
Picketts DJ, Lillicrap DP, Mueller CR (Feb 1993). "Synergy between transcription factors DBP and C/EBP compensates for a haemophilia B Leyden factor IX mutation". Nature Genetics. 3 (2): 175–9. doi:10.1038/ng0293-175. PMID 8499951. S2CID 6392603.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Shutler G, Glassco T, Kang X, Korneluk R, Mueller CR (Jun 1996). "Genomic structure of the human D-site binding protein (DBP) gene". Genomics. 34 (3): 334–9. doi:10.1006/geno.1996.0295. PMID 8786133.
Stubbs L, Carver E, Ashworth L, Lopez-Molina L (Jan 1996). "Location of the DBP transcription factor gene in human and mouse". Mammalian Genome. 7 (1): 65–7. doi:10.1007/s003359900016. PMID 8903733. S2CID 40284548.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Begbie M, Mueller C, Lillicrap D (Feb 1999). "Enhanced binding of HLF/DBP heterodimers represents one mechanism of PAR protein transactivation of the factor VIII and factor IX genes". DNA and Cell Biology. 18 (2): 165–73. doi:10.1089/104454999315556. PMID 10073576.
Lamprecht C, Mueller CR (Jun 1999). "D-site binding protein transactivation requires the proline- and acid-rich domain and involves the coactivator p300". The Journal of Biological Chemistry. 274 (25): 17643–8. doi:10.1074/jbc.274.25.17643. PMID 10364202.
Yan L, Miyake S, Okamura H (Jan 2000). "Distribution and circadian expression of dbp in SCN and extra-SCN areas in the mouse brain". Journal of Neuroscience Research. 59 (2): 291–5. doi:10.1002/(SICI)1097-4547(20000115)59:2<291::AID-JNR16>3.0.CO;2-O. PMID 10650888.
Smith JS, Tachibana I, Pohl U, Lee HK, Thanarajasingam U, Portier BP, Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN, Jenkins RB (Feb 2000). "A transcript map of the chromosome 19q-arm glioma tumor suppressor region". Genomics. 64 (1): 44–50. doi:10.1006/geno.1999.6101. PMID 10708517.
Newman JR, Keating AE (Jun 2003). "Comprehensive identification of human bZIP interactions with coiled-coil arrays". Science. 300 (5628): 2097–101. Bibcode:2003Sci...300.2097N. doi:10.1126/science.1084648. PMID 12805554. S2CID 36715183.

외부 링크

DBP+단백질,+미국 국립 의학 도서관 의학 주제 제목(MeSH)의 인간

이 기사에는 미국 국립 의학 도서관(미국 국립 의학 도서관)의 공공 도메인 텍스트가 포함되어 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000105516 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000059824 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: DBP D site of albumin promoter (albumin D-box) binding protein".

[pmid1535333-6] Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (Jun 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics. 13 (2): 293–300. doi:10.1016/0888-7543(92)90245-N. PMID 1535333.

[pmid7835883-7] Khatib ZA, Inaba T, Valentine M, Look AT (Sep 1994). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes". Genomics. 23 (2): 344–51. doi:10.1006/geno.1994.1510. PMID 7835883.

[pmid11914736-8] Melloul D, Marshak S, Cerasi E (Mar 2002). "Regulation of insulin gene transcription". Diabetologia. 45 (3): 309–26. doi:10.1007/s00125-001-0728-y. PMID 11914736.

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DBP(유전자)

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