|
EP3225632B1
(en)
|
1999-11-30 |
2020-05-06 |
Mayo Foundation for Medical Education and Research |
Antibodies binding to b7-h1, a novel immunoregulatory molecule
|
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
US7432351B1
(en)
|
2002-10-04 |
2008-10-07 |
Mayo Foundation For Medical Education And Research |
B7-H1 variants
|
|
EP1810026B1
(en)
*
|
2004-10-06 |
2018-04-18 |
Mayo Foundation For Medical Education And Research |
B7-h1 and pd-1 in treatment of renal cell carcinoma
|
|
EP2439272A3
(en)
*
|
2005-05-09 |
2013-07-31 |
Ono Pharmaceutical Co., Ltd. |
Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics
|
|
US9387242B2
(en)
|
2005-12-02 |
2016-07-12 |
Icahn School Of Medicine At Mount Sinai |
Chimeric viruses presenting non-native surface proteins and uses thereof
|
|
WO2007070660A2
(en)
|
2005-12-13 |
2007-06-21 |
President And Fellows Of Harvard College |
Scaffolds for cell transplantation
|
|
JP2010533649A
(ja)
|
2007-07-13 |
2010-10-28 |
ザ ジョンズ ホプキンス ユニバーシティー |
Ｂ７−ｄｃ改変体
|
|
EP2328919A2
(en)
*
|
2008-08-25 |
2011-06-08 |
Amplimmune, Inc. |
Pd-i antagonists and methods for treating infectious disease
|
|
EP2350129B1
(en)
|
2008-08-25 |
2015-06-10 |
Amplimmune, Inc. |
Compositions of pd-1 antagonists and methods of use
|
|
KR20240093808A
(ko)
|
2008-12-09 |
2024-06-24 |
제넨테크, 인크. |
항-ｐｄ-ｌ１ 항체 및 ｔ 세포 기능을 향상시키기 위한 그의 용도
|
|
WO2011066342A2
(en)
*
|
2009-11-24 |
2011-06-03 |
Amplimmune, Inc. |
Simultaneous inhibition of pd-l1/pd-l2
|
|
EP2542590B2
(en)
*
|
2010-03-05 |
2020-04-01 |
The Johns Hopkins University |
Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
|
|
US8906374B2
(en)
|
2010-04-20 |
2014-12-09 |
Cedars-Sinai Medical Center |
Combination therapy with CD4 lymphocyte depletion and mTOR inhibitors
|
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
|
US9783578B2
(en)
|
2010-06-25 |
2017-10-10 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
|
WO2012018538A2
(en)
*
|
2010-07-26 |
2012-02-09 |
Schering Corporation |
Bioassays for determining pd-1 modulation
|
|
WO2012048165A2
(en)
|
2010-10-06 |
2012-04-12 |
President And Fellows Of Harvard College |
Injectable, pore-forming hydrogels for materials-based cell therapies
|
|
EP2910572B1
(en)
*
|
2010-11-11 |
2017-09-06 |
Versitech Limited |
Soluble pd-1 variants, fusion constructs, and uses thereof
|
|
EP2701699B1
(en)
|
2011-04-28 |
2019-10-16 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
CN102298053B
(zh)
*
|
2011-05-20 |
2014-01-29 |
中山大学肿瘤防治中心 |
原发性肝细胞肝癌术后复发风险评估的组合抗体试剂盒
|
|
US9096642B2
(en)
|
2011-06-08 |
2015-08-04 |
Aurigene Discovery Technologies Limited |
Therapeutic compounds for immunomodulation
|
|
WO2012177788A1
(en)
*
|
2011-06-20 |
2012-12-27 |
La Jolla Institute For Allergy And Immunology |
Modulators of 4-1bb and immune responses
|
|
US10081684B2
(en)
|
2011-06-28 |
2018-09-25 |
Whitehead Institute For Biomedical Research |
Using sortases to install click chemistry handles for protein ligation
|
|
BR112014002353B1
(pt)
|
2011-08-01 |
2022-09-27 |
Genentech, Inc |
Usos de antagonistas de ligação do eixo pd-1 e inibidores de mek, composições farmacêuticas, e kit
|
|
GB201120527D0
(en)
*
|
2011-11-29 |
2012-01-11 |
Ucl Business Plc |
Method
|
|
WO2013112942A1
(en)
|
2012-01-25 |
2013-08-01 |
Dna Trix, Inc. |
Biomarkers and combination therapies using oncolytic virus and immunomodulation
|
|
EP3939572B1
(en)
|
2012-04-12 |
2024-03-27 |
Yale University |
Vehicles for controlled delivery of different pharmaceutical agents
|
|
CA2870309C
(en)
|
2012-04-16 |
2024-02-20 |
President And Fellows Of Harvard College |
Mesoporous silica compositions for modulating immune responses
|
|
AU2013266733B2
(en)
|
2012-05-25 |
2018-07-05 |
Cellectis |
Methods for engineering allogeneic and immunosuppressive resistant T cell for immunotherapy
|
|
JP6312659B2
(ja)
*
|
2012-05-31 |
2018-04-18 |
ジェネンテック， インコーポレイテッド |
Ｐｄ−１系結合アンタゴニスト及びｖｅｇｆアンタゴニストを用いた癌の治療方法
|
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
|
WO2014018979A1
(en)
|
2012-07-27 |
2014-01-30 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
US20150250837A1
(en)
*
|
2012-09-20 |
2015-09-10 |
Morningside Technology Ventures Ltd. |
Oncolytic virus encoding pd-1 binding agents and uses of the same
|
|
HUE050797T2
(hu)
*
|
2012-10-10 |
2021-01-28 |
Sangamo Therapeutics Inc |
T-sejt módosító vegyületek és alkalmazásaik
|
|
US9657082B2
(en)
|
2013-01-31 |
2017-05-23 |
Thomas Jefferson University |
PD-L1 and PD-L2-based fusion proteins and uses thereof
|
|
WO2014122271A1
(en)
*
|
2013-02-07 |
2014-08-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from diffuse large b-cell lymphomas
|
|
US9394368B2
(en)
|
2013-02-20 |
2016-07-19 |
Novartis Ag |
Treatment of cancer using humanized anti-EGFRvIII chimeric antigen receptor
|
|
ES2814962T3
(es)
|
2013-02-20 |
2021-03-29 |
Novartis Ag |
Fijación eficaz como objetivo de la leucemia humana primaria utilizando células T modificadas con receptor de antígeno quimérico anti-CD123
|
|
JP6456305B2
(ja)
*
|
2013-02-22 |
2019-01-23 |
キュアバック アーゲー |
ワクチン接種とｐｄ−１経路の阻害との組み合わせ
|
|
EP3578200A1
(en)
|
2013-02-22 |
2019-12-11 |
CureVac AG |
Combination of vaccination and inhibition of the pd-1 pathway
|
|
WO2014134084A2
(en)
*
|
2013-02-26 |
2014-09-04 |
Rongfu Wang |
Phf20 and jmjd3 compositions and methods of use in cancer immunotherapy
|
|
US9302005B2
(en)
|
2013-03-14 |
2016-04-05 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
|
SG11201507412SA
(en)
|
2013-03-14 |
2015-10-29 |
Icahn School Med Mount Sinai |
Newcastle disease viruses and uses thereof
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
CA2909160C
(en)
|
2013-04-09 |
2021-05-25 |
Lixte Biotechnology, Inc. |
Formulations of oxabicycloheptanes and oxabicycloheptenes
|
|
PT2992017T
(pt)
|
2013-05-02 |
2021-01-29 |
Anaptysbio Inc |
Anticorpos dirigidos contra a morte programada 1 (pd-1)
|
|
US10260038B2
(en)
|
2013-05-10 |
2019-04-16 |
Whitehead Institute For Biomedical Research |
Protein modification of living cells using sortase
|
|
EP3693398A1
(en)
|
2013-05-10 |
2020-08-12 |
Whitehead Institute for Biomedical Research |
In vitro production of red blood cells with sortaggable proteins
|
|
US11311575B2
(en)
|
2013-05-13 |
2022-04-26 |
Cellectis |
Methods for engineering highly active T cell for immunotherapy
|
|
US11077144B2
(en)
|
2013-05-13 |
2021-08-03 |
Cellectis |
CD19 specific chimeric antigen receptor and uses thereof
|
|
WO2014194293A1
(en)
|
2013-05-30 |
2014-12-04 |
Amplimmune, Inc. |
Improved methods for the selection of patients for pd-1 or b7-h4 targeted therapies, and combination therapies thereof
|
|
EP3010340A4
(en)
*
|
2013-06-22 |
2017-08-02 |
Nitor Therapeutics |
Compositions and methods for potentiating immune response, enhancing immunotherapy, and increasing vaccine potency
|
|
HUE057598T2
(hu)
|
2013-08-08 |
2022-05-28 |
Cytune Pharma |
IL-15 és IL-15R-alfa sushi domén alapú modulokinek
|
|
KR102457731B1
(ko)
|
2013-08-08 |
2022-10-21 |
싸이튠 파마 |
병용 약학 조성물
|
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
|
DK3508502T5
(da)
|
2013-09-20 |
2024-09-02 |
Bristol Myers Squibb Co |
Kombination af anti-lag-3-antistoffer og anti-pd-1-antistoffer til behandling af tumorer
|
|
EP3757130A1
(en)
|
2013-09-26 |
2020-12-30 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
EP3470081A1
(en)
|
2013-10-01 |
2019-04-17 |
Mayo Foundation for Medical Education and Research |
Methods for treating cancer in patients with elevated levels of bim
|
|
BR112016009643A8
(pt)
|
2013-11-01 |
2021-02-23 |
Univ Yale |
composição nanoparticulada, célula dendrítica artificial, método para estimular ou intensificar uma resposta imune e método para tratar câncer
|
|
WO2015066413A1
(en)
|
2013-11-01 |
2015-05-07 |
Novartis Ag |
Oxazolidinone hydroxamic acid compounds for the treatment of bacterial infections
|
|
US10556024B2
(en)
|
2013-11-13 |
2020-02-11 |
Whitehead Institute For Biomedical Research |
18F labeling of proteins using sortases
|
|
AU2014348657A1
(en)
|
2013-11-13 |
2016-05-19 |
Novartis Ag |
mTOR inhibitors for enhancing the immune response
|
|
PT3081576T
(pt)
|
2013-12-12 |
2019-10-15 |
Jiangsu Hengrui Medicine Co |
Anticorpo pd-1, fragmento de ligação ao antigénio do mesmo e aplicação médica do mesmo
|
|
EP3527587A1
(en)
*
|
2013-12-17 |
2019-08-21 |
F. Hoffmann-La Roche AG |
Combination therapy comprising ox40 binding agonists and pd-l1 binding antagonists
|
|
CN106459989B
(zh)
|
2013-12-19 |
2023-02-17 |
诺华股份有限公司 |
人间皮素嵌合抗原受体及其用途
|
|
WO2015100219A1
(en)
*
|
2013-12-23 |
2015-07-02 |
Oncomed Pharmaceuticals, Inc. |
Immunotherapy with binding agents
|
|
CA2936077C
(en)
*
|
2014-01-06 |
2020-06-30 |
Expression Pathology, Inc. |
Srm assay for pd-l1
|
|
KR102395498B1
(ko)
|
2014-01-06 |
2022-05-09 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
Pd1 및 pdl1 항체 및 백신 조합 및 면역요법을 위한 이들의 사용
|
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗ｐｄ-ｌ１之人類抗體
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對ｐｄ-１的人類抗體
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
CA2937035A1
(en)
*
|
2014-02-05 |
2015-08-13 |
Cedars-Sinai Medical Center |
Methods and compositions for treating cancer and infectious diseases
|
|
SG10201801562PA
(en)
|
2014-02-27 |
2018-04-27 |
Viralytics Ltd |
Combination method for treatment of cancer
|
|
CN114432440A
(zh)
*
|
2014-03-05 |
2022-05-06 |
百时美施贵宝公司 |
使用抗pd-1抗体与另一抗癌剂的组合治疗肾癌
|
|
US10618963B2
(en)
|
2014-03-12 |
2020-04-14 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
KR102248804B1
(ko)
|
2014-03-12 |
2021-05-11 |
예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 |
Cns의 질환 및 손상을 치료하기 위한 전신적 조절 t 세포 수준 또는 활성의 감소
|
|
EP3590529A1
(en)
|
2014-03-12 |
2020-01-08 |
CureVac AG |
Combination of vaccination and ox40 agonists
|
|
US10519237B2
(en)
|
2014-03-12 |
2019-12-31 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
US9394365B1
(en)
|
2014-03-12 |
2016-07-19 |
Yeda Research And Development Co., Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease
|
|
MY187246A
(en)
|
2014-03-14 |
2021-09-14 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
CN106163547A
(zh)
|
2014-03-15 |
2016-11-23 |
诺华股份有限公司 |
使用嵌合抗原受体治疗癌症
|
|
UA121383C2
(uk)
|
2014-03-24 |
2020-05-25 |
Новартіс Аг |
Органічні сполуки, що є монобактамами, для лікування бактеріальних інфекцій
|
|
US9975957B2
(en)
|
2014-03-31 |
2018-05-22 |
Genentech, Inc. |
Anti-OX40 antibodies and methods of use
|
|
IL293603B2
(en)
|
2014-04-07 |
2024-03-01 |
Novartis Ag |
Cancer treatment using chimeric antigen receptor (CAR) against CD19
|
|
US10682400B2
(en)
|
2014-04-30 |
2020-06-16 |
President And Fellows Of Harvard College |
Combination vaccine devices and methods of killing cancer cells
|
|
WO2015176033A1
(en)
|
2014-05-15 |
2015-11-19 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
|
|
WO2015179654A1
(en)
|
2014-05-22 |
2015-11-26 |
Mayo Foundation For Medical Education And Research |
Distinguishing antagonistic and agonistic anti b7-h1 antibodies
|
|
JP6847666B2
(ja)
|
2014-05-28 |
2021-03-24 |
アジェナス インコーポレイテッド |
抗ｇｉｔｒ抗体及びその使用法
|
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
MX2017000546A
(es)
|
2014-07-15 |
2017-03-08 |
Genentech Inc |
Composiciones para el tratamiento del cancer mediante el uso de antagonistas de union al eje de pd-1 e inhibidores de mek.
|
|
KR102594343B1
(ko)
|
2014-07-21 |
2023-10-26 |
노파르티스 아게 |
Cd33 키메라 항원 수용체를 사용한 암의 치료
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
WO2016014148A1
(en)
|
2014-07-23 |
2016-01-28 |
Mayo Foundation For Medical Education And Research |
Targeting dna-pkcs and b7-h1 to treat cancer
|
|
EP3660042B1
(en)
|
2014-07-31 |
2023-01-11 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
WO2016020836A1
(en)
|
2014-08-06 |
2016-02-11 |
Novartis Ag |
Quinolone derivatives as antibacterials
|
|
JP6245622B2
(ja)
|
2014-08-07 |
2017-12-13 |
学校法人兵庫医科大学 |
Ｉｌ−１８と分子標的抗体とを併用する癌治療薬
|
|
CA2994927A1
(en)
*
|
2014-08-08 |
2016-02-11 |
The Board Of Trustees Of The Leland Stanford Junior University |
High affinity pd-1 agents and methods of use
|
|
US10851149B2
(en)
|
2014-08-14 |
2020-12-01 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using GFR α-4 chimeric antigen receptor
|
|
CN107108744B
(zh)
|
2014-08-19 |
2020-09-25 |
诺华股份有限公司 |
抗cd123嵌合抗原受体(car)用于癌症治疗
|
|
ES2771926T3
(es)
|
2014-09-13 |
2020-07-07 |
Novartis Ag |
Terapias de combinación
|
|
HUE051193T2
(hu)
*
|
2014-09-16 |
2021-03-01 |
Innate Pharma |
Gátlási reakcióút semlegesítése limfocitákban
|
|
AU2015317608B2
(en)
|
2014-09-17 |
2021-03-11 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
US9616114B1
(en)
|
2014-09-18 |
2017-04-11 |
David Gordon Bermudes |
Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
|
|
JP2017535528A
(ja)
|
2014-10-03 |
2017-11-30 |
ノバルティス アーゲー |
組み合わせ治療
|
|
US10053683B2
(en)
|
2014-10-03 |
2018-08-21 |
Whitehead Institute For Biomedical Research |
Intercellular labeling of ligand-receptor interactions
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
WO2016057705A1
(en)
|
2014-10-08 |
2016-04-14 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
|
MA40035A
(fr)
|
2014-10-14 |
2016-04-21 |
Dana Farber Cancer Inst Inc |
Molécules d'anticorps de pd-l1 et leurs utilisations
|
|
AU2015335607B2
(en)
*
|
2014-10-24 |
2020-04-23 |
Calidi Biotherapeutics (Nevada), Inc. |
Combination immunotherapy approach for treatment of cancer
|
|
EP3835323A1
(en)
|
2014-10-29 |
2021-06-16 |
Five Prime Therapeutics, Inc. |
Combination therapy for cancer
|
|
CN107106593B
(zh)
*
|
2014-11-06 |
2021-05-07 |
百奥赛诺公司 |
影响肿瘤微环境的β-葡聚糖方法与组合物
|
|
SG10201914022QA
(en)
|
2014-11-13 |
2020-03-30 |
Univ Johns Hopkins |
Checkpoint blockade and microsatellite instability
|
|
CN108064244B
(zh)
|
2014-11-14 |
2021-09-17 |
诺华股份有限公司 |
抗体药物缀合物
|
|
WO2016089873A1
(en)
*
|
2014-12-02 |
2016-06-09 |
Celgene Corporation |
Combination therapies
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
EP3229837A4
(en)
|
2014-12-08 |
2018-05-30 |
Dana-Farber Cancer Institute, Inc. |
Methods for upregulating immune responses using combinations of anti-rgmb and anti-pd-1 agents
|
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗ｐｄ－１抗體類和使用彼等之方法
|
|
WO2016100561A2
(en)
*
|
2014-12-16 |
2016-06-23 |
Bristol-Myers Squibb Company |
Use of immune checkpoint inhibitors in central nervous systems neoplasms
|
|
PE20171044A1
(es)
|
2014-12-16 |
2017-07-19 |
Novartis Ag |
COMPUESTOS DE ISOXAZOL DE ACIDO HIDROXAMICO COMO INHIBIDORES DE LpxC
|
|
EP3233918A1
(en)
|
2014-12-19 |
2017-10-25 |
Novartis AG |
Combination therapies
|
|
CN105983097B
(zh)
*
|
2015-01-28 |
2021-06-08 |
华中科技大学同济医学院附属协和医院 |
一种抗肿瘤制剂及其制备方法
|
|
CA3012602A1
(en)
*
|
2015-01-30 |
2016-08-04 |
President And Fellows Of Harvard College |
Peritumoral and intratumoral materials for cancer therapy
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
ES2882157T3
(es)
*
|
2015-02-13 |
2021-12-01 |
Sorrento Therapeutics Inc |
Productos terapéuticos de anticuerpos que se unen a CTLA4
|
|
EP4279087A3
(en)
*
|
2015-02-26 |
2024-01-31 |
Merck Patent GmbH |
Pd-1 / pd-l1 inhibitors for the treatment of cancer
|
|
PE20171448A1
(es)
|
2015-03-10 |
2017-10-02 |
Aduro Biotech Inc |
Composiciones y metodos para activar la senalizacion dependiente del estimulador del gen de interferon
|
|
RS59878B1
(sr)
|
2015-03-23 |
2020-03-31 |
Bayer Pharma AG |
Anti-ceacam6 antitela i njihova primena
|
|
EP3280795B1
(en)
|
2015-04-07 |
2021-03-24 |
Novartis AG |
Combination of chimeric antigen receptor therapy and amino pyrimidine derivatives
|
|
JP7094533B2
(ja)
|
2015-04-10 |
2022-07-04 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
免疫細胞捕捉デバイスおよびその製造および使用方法
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
ES2813580T3
(es)
|
2015-04-17 |
2021-03-24 |
Bristol Myers Squibb Co |
Composiciones que comprenden una combinación de ipilimumab y nivolumab
|
|
WO2016168595A1
(en)
|
2015-04-17 |
2016-10-20 |
Barrett David Maxwell |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
KR20240046641A
(ko)
|
2015-04-17 |
2024-04-09 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
조율가능한 친화성을 갖는 면역조절 단백질
|
|
US12128069B2
(en)
|
2015-04-23 |
2024-10-29 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
US10174113B2
(en)
|
2015-04-28 |
2019-01-08 |
Bristol-Myers Squibb Company |
Treatment of PD-L1-negative melanoma using an anti-PD-1 antibody and an anti-CTLA-4 antibody
|
|
JP2018515474A
(ja)
|
2015-04-28 |
2018-06-14 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
抗ｐｄ−１抗体を使用するｐｄ−ｌ１陽性黒色腫の処置
|
|
IL274151B
(en)
|
2015-05-21 |
2022-07-01 |
Harpoon Therapeutics Inc |
Trispecific binding proteins and methods of use
|
|
WO2016191751A1
(en)
|
2015-05-28 |
2016-12-01 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
|
US11078278B2
(en)
|
2015-05-29 |
2021-08-03 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
|
KR20230028478A
(ko)
|
2015-05-29 |
2023-02-28 |
아게누스 인코포레이티드 |
항-ctla-4 항체 및 이의 사용 방법
|
|
TW201709929A
(zh)
|
2015-06-12 |
2017-03-16 |
宏觀基因股份有限公司 |
治療癌症的聯合療法
|
|
WO2016203432A1
(en)
|
2015-06-17 |
2016-12-22 |
Novartis Ag |
Antibody drug conjugates
|
|
MA42447A
(fr)
*
|
2015-07-13 |
2018-05-23 |
Cytomx Therapeutics Inc |
Anticorps anti-pd-1, anticorps anti-pd-1 activables, et leurs procédés d'utilisation
|
|
HUE053966T2
(hu)
|
2015-07-14 |
2021-08-30 |
Bristol Myers Squibb Co |
Eljárás rák kezelésére immunellenõrzõpont inhibitorral, antitest, amely köt programozott halál-1 receptorhoz (PD-1) vagy programozott halál ligandum 1-hez (PD-L1)
|
|
CA2991628C
(en)
|
2015-07-16 |
2020-04-07 |
Bioxcel Therapeutics, Inc. |
A novel approach for treatment of cancer using immunomodulation
|
|
CN116196426A
(zh)
|
2015-07-16 |
2023-06-02 |
百欧肯治疗有限公司 |
治疗癌症的组合物及方法
|
|
CN109476722A
(zh)
|
2015-07-21 |
2019-03-15 |
诺华股份有限公司 |
用于改善免疫细胞的功效和扩张的方法
|
|
DK3317301T3
(da)
|
2015-07-29 |
2021-06-28 |
Immutep Sas |
Kombinationsterapier omfattende antistofmolekyler mod lag-3
|
|
EP3328418A1
(en)
|
2015-07-29 |
2018-06-06 |
Novartis AG |
Combination therapies comprising antibody molecules to pd-1
|
|
CN108136003A
(zh)
|
2015-07-29 |
2018-06-08 |
诺华股份有限公司 |
抗pd-1和抗m-csf抗体在癌症治疗中的联合应用
|
|
AU2016298823A1
(en)
|
2015-07-29 |
2018-02-08 |
Novartis Ag |
Combination of PD-1 antagonist with an EGFR inhibitor
|
|
US20180207273A1
(en)
|
2015-07-29 |
2018-07-26 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
EP4450088A2
(en)
|
2015-07-30 |
2024-10-23 |
MacroGenics, Inc. |
Pd-1-binding molecules and methods of use thereof
|
|
CA2994241A1
(en)
|
2015-07-31 |
2017-02-09 |
University Of Florida Research Foundation, Inc. |
Hematopoietic stem cells in combinatorial therapy with immune checkpoint inhibitors against cancer
|
|
EA201890456A1
(ru)
|
2015-08-07 |
2018-07-31 |
ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ |
Новый слитый полипептид, специфичный в отношении lag-3 и pd-1
|
|
RS59688B1
(sr)
|
2015-08-11 |
2020-01-31 |
Novartis Ag |
5-bromo-2,6-di-(1h-pirazol-1-il)pirimidin-4-amin za upotrebu pri lečenju raka
|
|
CN115212301A
(zh)
|
2015-08-11 |
2022-10-21 |
卡利迪生物治疗有限公司 |
用以癌症治疗的天花疫苗
|
|
CN108780084B
(zh)
|
2015-09-03 |
2022-07-22 |
诺华股份有限公司 |
预测细胞因子释放综合征的生物标志物
|
|
ES2941968T3
(es)
|
2015-10-01 |
2023-05-29 |
The Whitehead Institute For Biomedical Res |
Marcaje de anticuerpos
|
|
MY190297A
(en)
|
2015-10-02 |
2022-04-12 |
Hoffmann La Roche |
Anti-pd1 antibodies and methods of use
|
|
MX2018003630A
(es)
|
2015-10-02 |
2018-08-01 |
F Hoffmann La Roche Ag |
Anticuerpos biespecificos para pd1 y tim3.
|
|
US11174315B2
(en)
|
2015-10-08 |
2021-11-16 |
Macrogenics, Inc. |
Combination therapy for the treatment of cancer
|
|
WO2017066561A2
(en)
|
2015-10-16 |
2017-04-20 |
President And Fellows Of Harvard College |
Regulatory t cell pd-1 modulation for regulating t cell effector immune responses
|
|
EP3365062B1
(en)
|
2015-10-19 |
2024-09-18 |
CG Oncology, Inc. |
Methods of treating solid or lymphatic tumors by combination therapy
|
|
MA44334A
(fr)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
|
|
US10875923B2
(en)
|
2015-10-30 |
2020-12-29 |
Mayo Foundation For Medical Education And Research |
Antibodies to B7-H1
|
|
US10273281B2
(en)
|
2015-11-02 |
2019-04-30 |
Five Prime Therapeutics, Inc. |
CD80 extracellular domain polypeptides and their use in cancer treatment
|
|
US11702477B2
(en)
|
2015-11-06 |
2023-07-18 |
Orionis Biosciences BV |
Bi-functional chimeric proteins and uses thereof
|
|
EP3377534A1
(en)
|
2015-11-18 |
2018-09-26 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-pd-1 antibody and an anti-ctla-4 antibody
|
|
SG10201913538VA
(en)
|
2015-11-23 |
2020-02-27 |
Five Prime Therapeutics Inc |
Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment
|
|
CA3007233A1
(en)
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
US10590169B2
(en)
*
|
2015-12-09 |
2020-03-17 |
Virogin Biotech Canada Ltd |
Compositions and methods for inhibiting CD279 interactions
|
|
UA125611C2
(uk)
|
2015-12-14 |
2022-05-04 |
Макродженікс, Інк. |
Біспецифічні молекули, що мають імунореактивність відносно pd-1 і ctla-4, і способи їх застосування
|
|
WO2017106656A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
|
US10392442B2
(en)
|
2015-12-17 |
2019-08-27 |
Bristol-Myers Squibb Company |
Use of anti-PD-1 antibody in combination with anti-CD27 antibody in cancer treatment
|
|
US20170198040A1
(en)
|
2015-12-18 |
2017-07-13 |
Novartis Ag |
ANTIBODIES TARGETING CD32b AND METHODS OF USE THEREOF
|
|
AU2016378721B2
(en)
|
2015-12-22 |
2024-01-11 |
Regeneron Pharmaceuticals, Inc. |
Combination of anti-PD-1 antibodies and bispecific anti-CD20/anti-CD3 antibodies to treat cancer
|
|
US11413340B2
(en)
|
2015-12-22 |
2022-08-16 |
Novartis Ag |
Mesothelin chimeric antigen receptor (CAR) and antibody against PD-L1 inhibitor for combined use in anticancer therapy
|
|
HRP20220525T1
(hr)
|
2015-12-23 |
2022-05-27 |
Modernatx, Inc. |
Postupci uporabe polinukleotida koji kodiraju ligand ox40
|
|
US20190178888A1
(en)
|
2016-01-11 |
2019-06-13 |
Technion Research & Development Foundation Limited |
Methods of determining prognosis of sepsis and treating same
|
|
US10889643B2
(en)
|
2016-01-11 |
2021-01-12 |
Universität Zürich |
Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof
|
|
CN109071627B
(zh)
|
2016-02-05 |
2023-04-04 |
奥里尼斯生物科学私人有限公司 |
Cd8结合剂
|
|
US11752238B2
(en)
|
2016-02-06 |
2023-09-12 |
President And Fellows Of Harvard College |
Recapitulating the hematopoietic niche to reconstitute immunity
|
|
US20200270265A1
(en)
|
2016-02-19 |
2020-08-27 |
Novartis Ag |
Tetracyclic pyridone compounds as antivirals
|
|
AU2017225869A1
(en)
|
2016-02-29 |
2018-09-06 |
Foundation Medicine, Inc. |
Methods of treating cancer
|
|
KR20180118175A
(ko)
|
2016-03-04 |
2018-10-30 |
노파르티스 아게 |
다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도
|
|
WO2017155981A1
(en)
|
2016-03-07 |
2017-09-14 |
Massachusetts Institute Of Technology |
Protein-chaperoned t-cell vaccines
|
|
EP3426271A4
(en)
|
2016-03-10 |
2019-10-16 |
Cold Genesys, Inc. |
METHODS OF TREATING SOLID OR LYMPHATIC TUMORS BY POLYTHERAPY
|
|
KR20190080825A
(ko)
|
2016-03-21 |
2019-07-08 |
다나-파버 캔서 인스티튜트 인크. |
T-세포 기능소실 상태-특이적 유전자 발현 조절인자 및 그 용도
|
|
JP7005508B2
(ja)
|
2016-03-24 |
2022-01-21 |
ノバルティス アーゲー |
ヒトライノウイルスの阻害剤としてのアルキニルヌクレオシド類似体
|
|
WO2017176925A1
(en)
|
2016-04-05 |
2017-10-12 |
Bristol-Myers Squibb Company |
Cytokine profiling analysis for predicting prognosis of a patient in need of an anti-cancer treatment
|
|
MX2018012488A
(es)
|
2016-04-13 |
2019-06-06 |
Vivia Biotech Sl |
Linfocitos t activados por bite ex vivo.
|
|
NZ746934A
(en)
|
2016-04-15 |
2023-11-24 |
Alpine Immune Sciences Inc |
Cd80 variant immunomodulatory proteins and uses thereof
|
|
EP3454887B1
(en)
|
2016-05-13 |
2021-01-20 |
Orionis Biosciences BV |
Targeted mutant interferon-beta and uses thereof
|
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
|
TWI822521B
(zh)
|
2016-05-13 |
2023-11-11 |
美商再生元醫藥公司 |
藉由投予pd-1抑制劑治療皮膚癌之方法
|
|
WO2017194782A2
(en)
|
2016-05-13 |
2017-11-16 |
Orionis Biosciences Nv |
Therapeutic targeting of non-cellular structures
|
|
AU2017268399B2
(en)
|
2016-05-18 |
2023-01-12 |
Modernatx, Inc. |
mRNA combination therapy for the treatment of cancer
|
|
PL3458083T3
(pl)
|
2016-05-18 |
2023-03-13 |
Modernatx, Inc. |
Polinukleotydy kodujące interleukinę-12 (il12) i ich zastosowania
|
|
CN109476718B
(zh)
|
2016-05-18 |
2023-07-04 |
莫得纳特斯公司 |
编码免疫调节多肽的mrna的组合及其用途
|
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
|
JP7194022B2
(ja)
|
2016-05-20 |
2022-12-21 |
イーライ リリー アンド カンパニー |
Ｎｏｔｃｈ阻害剤とＰＤ－１またはＰＤ－Ｌ１阻害剤との併用療法
|
|
CN109476751B
(zh)
|
2016-05-27 |
2024-04-19 |
艾吉纳斯公司 |
抗tim-3抗体及其使用方法
|
|
DK3464368T3
(da)
|
2016-06-02 |
2023-10-02 |
Bristol Myers Squibb Co |
Anvendelse af et anti-pd-1-antistof i kombination med et anti-cd30- antistof i lymfombehandling
|
|
RS64388B1
(sr)
|
2016-06-02 |
2023-08-31 |
Bristol Myers Squibb Co |
Pd-1 blokada nivolumabom kod refraktornog hočkinovog limfoma
|
|
JP2019517498A
(ja)
|
2016-06-03 |
2019-06-24 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
再発性小細胞肺癌の処置方法において使用するための抗ｐｄ−１抗体
|
|
US20200325226A1
(en)
|
2016-06-03 |
2020-10-15 |
Bristol-Myers Squibb Company |
Anti-pd-1 antibody for use in a method of treating a tumor
|
|
KR102702675B1
(ko)
|
2016-06-03 |
2024-09-05 |
브리스톨-마이어스 스큅 컴퍼니 |
결장직장암을 갖는 환자의 치료에서의 항-pd-1 항체의 용도
|
|
AU2017283768B2
(en)
|
2016-06-14 |
2019-05-23 |
Novartis Ag |
Crystalline form of (R)-4-(5-(cyclopropylethynyl)isoxazol-3-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide as an antibacterial agent
|
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
|
MX2018016227A
(es)
|
2016-06-24 |
2019-07-08 |
Infinity Pharmaceuticals Inc |
Terapias de combinacion.
|
|
US11098077B2
(en)
|
2016-07-05 |
2021-08-24 |
Chinook Therapeutics, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
JP2019522486A
(ja)
|
2016-07-13 |
2019-08-15 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
抗原提示細胞模倣足場およびそれを作製および使用するための方法
|
|
US11365252B2
(en)
|
2016-07-20 |
2022-06-21 |
University Of Utah Research Foundation |
CD229 CAR T cells and methods of use thereof
|
|
CN110214150A
(zh)
|
2016-07-28 |
2019-09-06 |
诺华股份有限公司 |
嵌合抗原受体和pd-1抑制剂的组合疗法
|
|
EP3490676A1
(en)
|
2016-07-29 |
2019-06-05 |
Eli Lilly and Company |
Combination therapy with merestinib and anti-pd-l1 or anti-pd-1 inhibitors for use in the treatment of cancer
|
|
JP2019527236A
(ja)
|
2016-08-01 |
2019-09-26 |
モレキュラー テンプレーツ，インコーポレイティド |
癌を治療するための免疫調節剤と組み合わせた低酸素活性化型プロドラッグの投与
|
|
JP2019528311A
(ja)
|
2016-08-03 |
2019-10-10 |
ネクストキュア インコーポレイテッド |
Ｌａｉｒシグナル伝達を調節するための組成物及び方法
|
|
EP3497134A4
(en)
*
|
2016-08-11 |
2020-01-15 |
The Council of the Queensland Institute of Medical Research |
IMMUNE MODULATION COMPOUNDS
|
|
WO2018037595A1
(ja)
*
|
2016-08-26 |
2018-03-01 |
哲治 奥野 |
微小血管血流低減剤およびその利用
|
|
MX2019002728A
(es)
|
2016-09-09 |
2019-08-16 |
Tg Therapeutics Inc |
Combinacion de un anticuerpo anti-cd20, inhibidor de quinasa pi3-delta, y anticuerpo anti-pd-1 o anti-pd-l1 para el tratamiento hematologico de los canceres.
|
|
TW201811788A
(zh)
|
2016-09-09 |
2018-04-01 |
瑞士商諾華公司 |
作為抗病毒劑之多環吡啶酮化合物
|
|
WO2018048975A1
(en)
|
2016-09-09 |
2018-03-15 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-mesothelin antibody in cancer treatment
|
|
KR102561356B1
(ko)
*
|
2016-09-14 |
2023-08-03 |
애브비 바이오테라퓨틱스 인크. |
항-pd-1 항체 및 이의 용도
|
|
ES2982558T3
(es)
|
2016-09-21 |
2024-10-16 |
Nextcure Inc |
Anticuerpos para Siglec-15 y métodos de uso de los mismos
|
|
US11077178B2
(en)
|
2016-09-21 |
2021-08-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptor (CAR) that targets chemokine receptor CCR4 and its use
|
|
EP4360714A3
(en)
|
2016-09-21 |
2024-07-24 |
Nextcure, Inc. |
Antibodies for siglec-15 and methods of use thereof
|
|
JP7274413B2
(ja)
|
2016-09-23 |
2023-05-16 |
マレンゴ・セラピューティクス，インコーポレーテッド |
ラムダ及びカッパ軽鎖を含む多重特異性抗体分子
|
|
JOP20190061A1
(ar)
|
2016-09-28 |
2019-03-26 |
Novartis Ag |
مثبطات بيتا-لاكتاماز
|
|
MX2019003886A
(es)
|
2016-10-07 |
2019-08-05 |
Novartis Ag |
Receptores de antigenos quimericos para el tratamiento del cancer.
|
|
WO2018071500A1
(en)
|
2016-10-11 |
2018-04-19 |
Agenus Inc. |
Anti-lag-3 antibodies and methods of use thereof
|
|
WO2018071576A1
(en)
|
2016-10-14 |
2018-04-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Treatment of tumors by inhibition of cd300f
|
|
TW201819380A
(zh)
|
2016-10-18 |
2018-06-01 |
瑞士商諾華公司 |
作為抗病毒劑之稠合四環吡啶酮化合物
|
|
CN110114368B
(zh)
|
2016-10-24 |
2024-08-02 |
奥睿尼斯生物科学私人有限公司 |
靶向突变干扰素-γ及其用途
|
|
US20200024324A1
(en)
|
2016-10-27 |
2020-01-23 |
Io Biotech Aps |
New pdl2 compounds
|
|
WO2018085468A1
(en)
|
2016-11-01 |
2018-05-11 |
Anaptysbio, Inc. |
Antibodies directed against programmed death- 1 (pd-1)
|
|
AU2017353427A1
(en)
|
2016-11-02 |
2019-05-16 |
Bristol-Myers Squibb Company |
Bispecific antibody against BCMA and CD3 and an immunological drug for combined use in treating multiple myeloma
|
|
PL3535298T3
(pl)
|
2016-11-02 |
2021-12-27 |
Jounce Therapeutics, Inc. |
Przeciwciała wobec pd-1 i ich zastosowanie
|
|
WO2018101448A1
(en)
|
2016-11-30 |
2018-06-07 |
Kyowa Hakko Kirin Co., Ltd. |
Method of treating cancer using anti-ccr4 antibody and anti-pd-1 antibody
|
|
WO2018102786A1
(en)
|
2016-12-03 |
2018-06-07 |
Juno Therapeutics, Inc. |
Methods for modulation of car-t cells
|
|
WO2018106864A1
(en)
|
2016-12-07 |
2018-06-14 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
DK3551660T5
(da)
|
2016-12-07 |
2024-09-02 |
Agenus Inc |
Anti-ctla-4-antistoffer og fremgangsmåder til anvendelse deraf
|
|
US11180535B1
(en)
|
2016-12-07 |
2021-11-23 |
David Gordon Bermudes |
Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
|
|
CN110382545A
(zh)
|
2017-01-09 |
2019-10-25 |
泰萨罗公司 |
用抗pd-1抗体治疗癌症的方法
|
|
US11613785B2
(en)
|
2017-01-09 |
2023-03-28 |
Onkosxcel Therapeutics, Llc |
Predictive and diagnostic methods for prostate cancer
|
|
EA201991696A1
(ru)
|
2017-01-13 |
2020-02-05 |
Эйдженус Инк. |
Т-клеточные рецепторы, связывающиеся с ny-eso-1, и способы их применения
|
|
WO2018134279A1
(en)
|
2017-01-18 |
2018-07-26 |
Pieris Pharmaceuticals Gmbh |
Novel fusion polypeptides specific for lag-3 and pd-1
|
|
TWI832600B
(zh)
|
2017-01-20 |
2024-02-11 |
美商健臻公司 |
骨靶向抗體
|
|
WO2018134784A1
(en)
|
2017-01-20 |
2018-07-26 |
Novartis Ag |
Combination therapy for the treatment of cancer
|
|
TWI787230B
(zh)
|
2017-01-20 |
2022-12-21 |
法商賽諾菲公司 |
抗ＴＧＦ-β抗體及其用途
|
|
JOP20190187A1
(ar)
|
2017-02-03 |
2019-08-01 |
Novartis Ag |
مترافقات عقار جسم مضاد لـ ccr7
|
|
US10906985B2
(en)
|
2017-02-06 |
2021-02-02 |
Orionis Biosciences, Inc. |
Targeted engineered interferon and uses thereof
|
|
MX2019009255A
(es)
|
2017-02-06 |
2019-11-05 |
Orionis Biosciences Nv |
Proteínas quiméricas dirigidas y sus usos.
|
|
WO2018151820A1
(en)
|
2017-02-16 |
2018-08-23 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
CN117442719A
(zh)
|
2017-02-21 |
2024-01-26 |
瑞泽恩制药公司 |
用于治疗肺癌的抗pd-1抗体
|
|
US11459394B2
(en)
|
2017-02-24 |
2022-10-04 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof
|
|
KR102700956B1
(ko)
|
2017-02-28 |
2024-09-03 |
사노피 |
치료적 rna
|
|
WO2018163051A1
(en)
|
2017-03-06 |
2018-09-13 |
Novartis Ag |
Methods of treatment of cancer with reduced ubb expression
|
|
EP3596469A1
(en)
|
2017-03-12 |
2020-01-22 |
Yeda Research and Development Co., Ltd. |
Methods of diagnosing and prognosing cancer
|
|
WO2018167780A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of prognosing and treating cancer
|
|
SG11201907769XA
(en)
|
2017-03-16 |
2019-09-27 |
Alpine Immune Sciences Inc |
Cd80 variant immunomodulatory proteins and uses thereof
|
|
WO2018183608A1
(en)
|
2017-03-31 |
2018-10-04 |
Five Prime Therapeutics, Inc. |
Combination therapy for cancer using anti-gitr antibodies
|
|
WO2018185618A1
(en)
|
2017-04-03 |
2018-10-11 |
Novartis Ag |
Anti-cdh6 antibody drug conjugates and anti-gitr antibody combinations and methods of treatment
|
|
KR102461885B1
(ko)
|
2017-04-03 |
2022-11-03 |
에프. 호프만-라 로슈 아게 |
항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체
|
|
CR20190435A
(es)
|
2017-04-05 |
2019-11-12 |
Hoffmann La Roche |
Anticuerpos biespecíficos de unión específica a pd1 y lag3
|
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
KR20240017409A
(ko)
|
2017-04-13 |
2024-02-07 |
아게누스 인코포레이티드 |
항-cd137 항체 및 이의 사용 방법
|
|
JP2020517256A
(ja)
|
2017-04-19 |
2020-06-18 |
エルスター セラピューティクス， インコーポレイテッド |
多重特異性分子およびその使用
|
|
MX2019012465A
(es)
|
2017-04-20 |
2020-07-27 |
Adc Therapeutics Sa |
Terapia combinada con un conjugado de anticuerpo y farmaco anti-cd25.
|
|
EP3612234B1
(en)
|
2017-04-20 |
2024-03-13 |
ADC Therapeutics SA |
Combination therapy with an anti-axl antibody-drug conjugate
|
|
AR111419A1
(es)
|
2017-04-27 |
2019-07-10 |
Novartis Ag |
Compuestos fusionados de indazol piridona como antivirales
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
EP3615566B1
(en)
|
2017-04-28 |
2023-12-20 |
Marengo Therapeutics, Inc. |
Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
|
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
WO2018201014A1
(en)
|
2017-04-28 |
2018-11-01 |
Five Prime Therapeutics, Inc. |
Methods of treatment with cd80 extracellular domain polypeptides
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
PT3618863T
(pt)
|
2017-05-01 |
2023-08-23 |
Agenus Inc |
Anticorpos anti-tigit e seus métodos de utilização
|
|
AR111658A1
(es)
|
2017-05-05 |
2019-08-07 |
Novartis Ag |
2-quinolinonas tricíclicas como agentes antibacteriales
|
|
JOP20190256A1
(ar)
|
2017-05-12 |
2019-10-28 |
Icahn School Med Mount Sinai |
فيروسات داء نيوكاسل واستخداماتها
|
|
BR112019023855B1
(pt)
|
2017-05-12 |
2021-11-30 |
Harpoon Therapeutics, Inc |
Proteínas de ligação à mesotelina
|
|
US11685787B2
(en)
|
2017-05-16 |
2023-06-27 |
Bristol-Myers Squibb Company |
Treatment of cancer with anti-GITR agonist antibodies
|
|
JP7285220B2
(ja)
|
2017-05-18 |
2023-06-01 |
モデルナティエックス インコーポレイテッド |
連結したインターロイキン－１２（ｉｌ１２）ポリペプチドをコードするポリヌクレオチドを含む脂質ナノ粒子
|
|
MX2019014023A
(es)
|
2017-05-24 |
2020-02-17 |
Novartis Ag |
Proteinas de anticuerpo injertadas con citocina y metodos de uso en el tratamiento del cancer.
|
|
WO2018215937A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer
|
|
US20200362058A1
(en)
|
2017-05-24 |
2020-11-19 |
Novartis Ag |
Antibody-cytokine engrafted proteins and methods of use
|
|
CN110678200B
(zh)
|
2017-05-30 |
2024-05-17 |
百时美施贵宝公司 |
包含抗lag-3抗体或抗lag-3抗体和抗pd-1或抗pd-l1抗体的组合物
|
|
LT3631454T
(lt)
|
2017-05-30 |
2023-11-27 |
Bristol-Myers Squibb Company |
Lag-3 atžvilgiu teigiamų navikų gydymas
|
|
MX2019012038A
(es)
|
2017-05-30 |
2019-11-18 |
Bristol Myers Squibb Co |
Composiciones que comprenden una combinacion de un anticuerpo anti gen 3 de activacion del linfocito (lag-3), un inhibidor de la trayectoria del receptor de muerte programada 1 (pd-1), y un agente inmunoterapeutico.
|
|
WO2018222901A1
(en)
|
2017-05-31 |
2018-12-06 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
AU2018277545A1
(en)
|
2017-05-31 |
2019-12-19 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that immunospecifically bind to BTN1A1
|
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
|
US20200181274A1
(en)
|
2017-06-01 |
2020-06-11 |
Novartis Ag |
Bispecific antibodies that bind cd 123 cd3
|
|
EP3630126A4
(en)
*
|
2017-06-02 |
2021-03-17 |
The Penn State Research Foundation |
CERAMIDE NANOLIPOSOMES, COMPOSITIONS AND METHODS OF USE FOR IMMUNOTHERAPY
|
|
EP3630132A1
(en)
|
2017-06-02 |
2020-04-08 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods for treatment using adoptive cell therapy
|
|
JP2020522562A
(ja)
|
2017-06-06 |
2020-07-30 |
ストキューブ アンド シーオー．， インコーポレイテッド |
Ｂｔｎ１ａ１又はｂｔｎ１ａ１リガンドに結合する抗体及び分子を用いて癌を治療する方法
|
|
MX2019015042A
(es)
|
2017-06-14 |
2020-08-06 |
Adc Therapeutics Sa |
Regimen de dosificacion.
|
|
BR112019027104A2
(pt)
|
2017-06-22 |
2020-08-18 |
Novartis Ag |
moléculas de anticorpo para cd73 e usos das mesmas
|
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
CA3067602A1
(en)
|
2017-06-29 |
2019-01-03 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
|
WO2019023525A1
(en)
*
|
2017-07-28 |
2019-01-31 |
Dana-Farber Cancer Institute, Inc. |
ENHANCED IMMUNOTHERAPY OF CANCER USING TARGETED TRANSCRIPTION MODULATORS
|
|
JP7274454B2
(ja)
|
2017-07-28 |
2023-05-16 |
ブリストル－マイヤーズ スクイブ カンパニー |
チェックポイント阻害薬のための予測末梢血バイオマーカー
|
|
CN111093669A
(zh)
*
|
2017-08-14 |
2020-05-01 |
法斯瑞斯公司 |
用于治疗癌症的腺苷受体拮抗剂的微颗粒制剂
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
ES2977589T3
(es)
|
2017-08-18 |
2024-08-27 |
Cothera Bioscience Inc |
Forma polimórfica de TG02
|
|
EP3676616A1
(en)
|
2017-08-28 |
2020-07-08 |
Bristol-Myers Squibb Company |
Tim-3 antagonists for the treatment and diagnosis of cancers
|
|
MA50084A
(fr)
|
2017-09-04 |
2020-07-15 |
Agenus Inc |
Récepteurs de lymphocytes t qui se lient à des phosphopeptides spécifiques de la leucémie de lignée mixte (mll) et méthodes d'utilisation de ces derniers
|
|
WO2019051164A1
(en)
|
2017-09-07 |
2019-03-14 |
Augusta University Research Institute, Inc. |
ANTIBODIES AGAINST PROTEIN 1 OF PROGRAMMED CELL DEATH
|
|
CN111465612B
(zh)
|
2017-10-13 |
2024-08-27 |
哈普恩治疗公司 |
B细胞成熟抗原结合蛋白
|
|
CN109662966A
(zh)
*
|
2017-10-16 |
2019-04-23 |
北京莱科金基因科技有限责任公司 |
伊曲茶碱在制备用于肿瘤治疗的药物中的用途
|
|
WO2019077062A1
(en)
|
2017-10-18 |
2019-04-25 |
Vivia Biotech, S.L. |
C-CELLS ACTIVATED BY BIT
|
|
CN111511370A
(zh)
|
2017-11-01 |
2020-08-07 |
朱诺治疗学股份有限公司 |
对b细胞成熟抗原具有特异性的抗体和嵌合抗原受体
|
|
CA3082010A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for b-cell maturation antigen (bcma)
|
|
US12031975B2
(en)
|
2017-11-01 |
2024-07-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
MX2020004756A
(es)
|
2017-11-16 |
2020-08-20 |
Novartis Ag |
Terapias de combinacion.
|
|
EP3710455A1
(en)
|
2017-11-17 |
2020-09-23 |
Novartis AG |
Novel dihydroisoxazole compounds and their use for the treatment of hepatitis b
|
|
AR113696A1
(es)
|
2017-11-17 |
2020-06-03 |
Merck Sharp & Dohme |
Anticuerpos específicos para el transcrito similar a la inmunoglobulina tipo 3 (ilt3) y sus usos
|
|
CA3083949A1
(en)
|
2017-11-30 |
2020-06-06 |
Novartis Ag |
Bcma-targeting chimeric antigen receptor, and uses thereof
|
|
WO2019113464A1
(en)
|
2017-12-08 |
2019-06-13 |
Elstar Therapeutics, Inc. |
Multispecific molecules and uses thereof
|
|
US11946094B2
(en)
|
2017-12-10 |
2024-04-02 |
Augusta University Research Institute, Inc. |
Combination therapies and methods of use thereof
|
|
KR20200110745A
(ko)
|
2017-12-15 |
2020-09-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
항 - ｃｃｔ5 결합 분자 및 이의 사용 방법
|
|
JP2021507906A
(ja)
|
2017-12-20 |
2021-02-25 |
ノバルティス アーゲー |
抗ウイルス剤としての融合三環式ピラゾロ−ジヒドロピラジニル−ピリドン化合物
|
|
US11324774B2
(en)
|
2018-01-05 |
2022-05-10 |
Augusta University Research Institute, Inc. |
Compositions of oral alkaline salts and metabolic acid inducers and uses thereof
|
|
CA3125731A1
(en)
|
2018-01-12 |
2019-07-18 |
KDAc Therapeutics, Inc. |
Combination of a selective histone deacetylase 3 (hdac3) inhibitor and an immunotherapy agent for the treatment of cancer
|
|
US11572405B2
(en)
|
2018-01-12 |
2023-02-07 |
Bristol-Myers Squibb Company |
Combination therapy with anti-IL-8 antibodies and anti-PD-1 antibodies for treating cancer
|
|
EP3743061A1
(en)
|
2018-01-22 |
2020-12-02 |
Pascal Biosciences Inc. |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
|
CA3089469A1
(en)
|
2018-01-23 |
2019-08-01 |
Nextcure, Inc. |
B7-h4 antibodies and methods of use thereof
|
|
CN111655730A
(zh)
|
2018-01-31 |
2020-09-11 |
豪夫迈·罗氏有限公司 |
包含与lag3结合的抗原结合位点的双特异性抗体
|
|
CN111971059A
(zh)
|
2018-01-31 |
2020-11-20 |
细胞基因公司 |
使用过继细胞疗法和检查点抑制剂的组合疗法
|
|
WO2019157124A1
(en)
|
2018-02-08 |
2019-08-15 |
Bristol-Myers Squibb Company |
Combination of a tetanus toxoid, anti-ox40 antibody and/or anti-pd-1 antibody to treat tumors
|
|
CN111801331A
(zh)
|
2018-02-28 |
2020-10-20 |
诺华股份有限公司 |
吲哚-2-羰基化合物及其用于治疗乙型肝炎的用途
|
|
WO2019169229A1
(en)
|
2018-03-01 |
2019-09-06 |
Nextcure, Inc. |
Klrg1 binding compositions and methods of use thereof
|
|
CA3093036A1
(en)
|
2018-03-07 |
2019-09-12 |
Pfizer Inc. |
Anti-pd-1 antibody compositions
|
|
RU2020133451A
(ru)
|
2018-03-12 |
2022-04-12 |
Инститьют Насьонал Де Ла Санте Et De La Решерш Медикаль (Инсерм) |
Применение терапевтически эффективной комбинации химиотерапиии и ингибитора контрольной точки иммунного ответа с миметиком ограничения калорийности для лечения рака
|
|
WO2019178362A1
(en)
|
2018-03-14 |
2019-09-19 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
KR102411489B1
(ko)
|
2018-03-14 |
2022-06-23 |
서피스 온콜로지, 인크. |
Cd39에 결합하는 항체 및 이의 용도
|
|
WO2019178364A2
(en)
|
2018-03-14 |
2019-09-19 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
US20210361734A1
(en)
*
|
2018-03-19 |
2021-11-25 |
9 Meters Biopharma, Inc. |
Compositions and methods for potentiating immune checkpoint inhibitor therapy
|
|
WO2019195658A1
(en)
|
2018-04-05 |
2019-10-10 |
Dana-Farber Cancer Institute, Inc. |
Sting levels as a biomarker for cancer immunotherapy
|
|
WO2019200256A1
(en)
|
2018-04-12 |
2019-10-17 |
Bristol-Myers Squibb Company |
Anticancer combination therapy with cd73 antagonist antibody and pd-1/pd-l1 axis antagonist antibody
|
|
TW201943428A
(zh)
|
2018-04-16 |
2019-11-16 |
大陸商上海岸闊醫藥科技有限公司 |
預防或治療腫瘤療法副作用的方法
|
|
EP3781265A2
(en)
|
2018-04-17 |
2021-02-24 |
Celldex Therapeutics, Inc. |
Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs
|
|
US11524991B2
(en)
|
2018-04-18 |
2022-12-13 |
Xencor, Inc. |
PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof
|
|
CA3097625A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Il-15/il-15ra heterodimeric fc fusion proteins and uses thereof
|
|
JP2021522239A
(ja)
|
2018-04-26 |
2021-08-30 |
アジェナス インコーポレイテッド |
熱ショックタンパク質結合ペプチド組成物およびその使用方法
|
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
|
US20210396739A1
(en)
|
2018-05-01 |
2021-12-23 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
MX2020012418A
(es)
|
2018-05-23 |
2021-04-28 |
Adc Therapeutics Sa |
Adyuvante molecular.
|
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
CN112165974B
(zh)
|
2018-05-31 |
2024-11-08 |
诺华股份有限公司 |
乙型肝炎抗体
|
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
EP3801617A1
(en)
|
2018-06-01 |
2021-04-14 |
Novartis Ag |
Dosing of a bispecific antibody that bind cd123 and cd3
|
|
EP3802611A2
(en)
|
2018-06-01 |
2021-04-14 |
Novartis AG |
Binding molecules against bcma and uses thereof
|
|
MX2020013122A
(es)
|
2018-06-03 |
2021-04-13 |
Lamkap Bio Beta Ltd |
Anticuerpos biespecificos contra anticuerpos biespecíficos que se unen al antígeno carcinoembrionario humano (ceacam5) y grupo de diferenciación (cd47).
|
|
US11505782B2
(en)
|
2018-06-04 |
2022-11-22 |
Calidi Biotherapeutics, Inc. |
Cell-based vehicles for potentiation of viral therapy
|
|
SG11202011830SA
(en)
|
2018-06-13 |
2020-12-30 |
Novartis Ag |
Bcma chimeric antigen receptors and uses thereof
|
|
TW202005985A
(zh)
|
2018-06-21 |
2020-02-01 |
美商再生元醫藥公司 |
用雙特異性抗ＣＤ３ｘＭＵＣ１６抗體及抗ＰＤ－１抗體治療癌症的方法
|
|
WO2020010250A2
(en)
|
2018-07-03 |
2020-01-09 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
EP3820573B1
(en)
|
2018-07-10 |
2023-08-09 |
Novartis AG |
3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and their use in the treatment of ikaros family zinc finger 2 (ikzf2)-dependent diseases
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
WO2020014583A1
(en)
|
2018-07-13 |
2020-01-16 |
Bristol-Myers Squibb Company |
Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a mehtod of treating a cancer or a solid tumor
|
|
WO2020021061A1
(en)
|
2018-07-26 |
2020-01-30 |
Pieris Pharmaceuticals Gmbh |
Humanized anti-pd-1 antibodies and uses thereof
|
|
CA3107660A1
(en)
|
2018-07-26 |
2020-01-30 |
Bristol-Myers Squibb Company |
Lag-3 combination therapy for the treatment of cancer
|
|
CN112955221A
(zh)
|
2018-08-27 |
2021-06-11 |
皮里斯制药有限公司 |
包含cd137/her2双特异性试剂和pd-1轴抑制剂的组合疗法及其用途
|
|
CN109053895B
(zh)
*
|
2018-08-30 |
2020-06-09 |
中山康方生物医药有限公司 |
抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
|
|
US20210340279A1
(en)
|
2018-08-31 |
2021-11-04 |
Yale University |
Compositions and methods of using cell-penetrating antibodies in combination with immune checkpoint modulators
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
CA3107137A1
(en)
|
2018-09-07 |
2020-03-12 |
Pfizer Inc. |
Anti-avb8 antibodies and compositions and uses thereof
|
|
WO2020053742A2
(en)
|
2018-09-10 |
2020-03-19 |
Novartis Ag |
Anti-hla-hbv peptide antibodies
|
|
US11234986B2
(en)
|
2018-09-11 |
2022-02-01 |
Curis, Inc. |
Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety
|
|
CN112996789A
(zh)
|
2018-09-12 |
2021-06-18 |
诺华股份有限公司 |
抗病毒吡啶并吡嗪二酮化合物
|
|
CN113396160A
(zh)
|
2018-09-19 |
2021-09-14 |
国家医疗保健研究所 |
治疗对免疫检查点疗法具有抗性的癌症的方法和药物组合物
|
|
JP2022501361A
(ja)
|
2018-09-19 |
2022-01-06 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
バリアントｃｄ８０融合タンパク質および関連構築物の方法および使用
|
|
IL297931B1
(en)
|
2018-09-25 |
2024-11-01 |
Harpoon Therapeutics Inc |
DLL3 binding proteins and methods of use
|
|
JP7465272B2
(ja)
|
2018-09-27 |
2024-04-10 |
マレンゴ・セラピューティクス，インコーポレーテッド |
Ｃｓｆ１ｒ／ｃｃｒ２多特異性抗体
|
|
WO2020069409A1
(en)
|
2018-09-28 |
2020-04-02 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
|
US20220047633A1
(en)
|
2018-09-28 |
2022-02-17 |
Novartis Ag |
Cd22 chimeric antigen receptor (car) therapies
|
|
AU2019350592B2
(en)
|
2018-09-29 |
2024-09-26 |
Novartis Ag |
Process of manufacture of a compound for inhibiting the activity of SHP2
|
|
WO2020070053A1
(en)
|
2018-10-01 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
US11358999B2
(en)
|
2018-10-03 |
2022-06-14 |
Xencor, Inc. |
IL-12 heterodimeric Fc-fusion proteins
|
|
US11377477B2
(en)
|
2018-10-12 |
2022-07-05 |
Xencor, Inc. |
PD-1 targeted IL-15/IL-15RALPHA fc fusion proteins and uses in combination therapies thereof
|
|
WO2020079692A1
(en)
|
2018-10-17 |
2020-04-23 |
Biolinerx Ltd. |
Treatment of metastatic pancreatic adenocarcinoma
|
|
WO2020089811A1
(en)
|
2018-10-31 |
2020-05-07 |
Novartis Ag |
Dc-sign antibody drug conjugates
|
|
PE20211058A1
(es)
|
2018-11-01 |
2021-06-07 |
Juno Therapeutics Inc |
Receptores de antigenos quimericos especificos para el miembro d del grupo 5 de la clase c del receptor acoplado a proteina g (gprc5d)
|
|
AU2019372331A1
(en)
|
2018-11-01 |
2021-05-27 |
Juno Therapeutics, Inc. |
Methods for treatment using chimeric antigen receptors specific for B-cell maturation antigen
|
|
US20220001026A1
(en)
|
2018-11-08 |
2022-01-06 |
Modernatx, Inc. |
Use of mrna encoding ox40l to treat cancer in human patients
|
|
MX2021005686A
(es)
|
2018-11-14 |
2021-07-07 |
Bayer Ag |
Combinacion farmaceutica de anti-ceacam6 y anticuerpos anti-pd-1 o anti-pd-l1 para el tratamiento del cancer.
|
|
HUE067601T2
(hu)
|
2018-11-14 |
2024-10-28 |
Regeneron Pharmaceuticals Inc |
PD-1 inhibitorok intraléziós beadása a bõrrák kezelésére
|
|
MX2021005734A
(es)
|
2018-11-16 |
2021-09-10 |
Juno Therapeutics Inc |
Metodos de dosificacion de celulas t modificadas para el tratamiento de malignidades de celulas b.
|
|
AU2019379325A1
(en)
|
2018-11-16 |
2021-06-03 |
Genexine, Inc. |
Method of treating a tumor with a combination of IL-7 protein and an immune checkpoint inhibitor
|
|
WO2020109328A1
(en)
|
2018-11-26 |
2020-06-04 |
Debiopharm International S.A. |
Combination treatment of hiv infections
|
|
ES2971964T3
(es)
|
2018-11-28 |
2024-06-10 |
Inst Nat Sante Rech Med |
Métodos y kit para someter a ensayo el potencial lítico de células efectoras inmunitarias
|
|
CN113710256A
(zh)
|
2018-11-30 |
2021-11-26 |
朱诺治疗学股份有限公司 |
使用过继细胞疗法的治疗方法
|
|
EP3891270A1
(en)
|
2018-12-07 |
2021-10-13 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
WO2020127059A1
(en)
|
2018-12-17 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sulconazole as a furin inhibitor
|
|
CN113271945A
(zh)
|
2018-12-20 |
2021-08-17 |
诺华股份有限公司 |
包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案和药物组合
|
|
WO2020132646A1
(en)
|
2018-12-20 |
2020-06-25 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
|
BR112021012066A2
(pt)
|
2018-12-21 |
2021-11-03 |
Onxeo |
Novas moléculas de ácido nucleico conjugadas e seus usos
|
|
AU2019409132A1
(en)
|
2018-12-21 |
2021-07-15 |
Novartis Ag |
Antibodies to PMEL17 and conjugates thereof
|
|
WO2020148338A1
(en)
|
2019-01-15 |
2020-07-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Mutated interleukin-34 (il-34) polypeptides and uses thereof in therapy
|
|
CA3123886A1
(en)
|
2019-01-17 |
2020-07-23 |
James DAHLMAN |
Drug delivery systems containing oxidized cholesterols
|
|
MX2021008605A
(es)
|
2019-01-21 |
2021-10-26 |
Sanofi Sa |
Arn terapéutico y anticuerpos anti-pd1 para canceres de tumor sólido en estadio avanzado.
|
|
WO2020160050A1
(en)
|
2019-01-29 |
2020-08-06 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1)
|
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
EP3924521A4
(en)
|
2019-02-15 |
2023-03-29 |
IncellDx, Inc. |
BLADDER-ASSOCIATED SPECIMEN ASSAY, IDENTIFICATION AND TREATMENT OF BLADDER-ASSOCIATED NEOPLASIA, AND KITS FOR USE THEREOF
|
|
WO2020165833A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
US20220088075A1
(en)
|
2019-02-22 |
2022-03-24 |
The Trustees Of The University Of Pennsylvania |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
US20220259313A1
(en)
|
2019-02-28 |
2022-08-18 |
Regeneron Pharmaceuticals, Inc. |
Administration of a pd-1 inhibitor for for treating skin cancer
|
|
MA55204A
(fr)
|
2019-03-06 |
2022-01-12 |
Regeneron Pharma |
Inhibiteurs de la voie il-4/il-13 pour une efficacité améliorée dans le traitement du cancer
|
|
MA55516A
(fr)
|
2019-03-26 |
2022-02-09 |
Univ Michigan Regents |
Agents de dégradation, à petites molécules, de stat3
|
|
US20220185831A1
(en)
|
2019-03-29 |
2022-06-16 |
The Regents Of The University Of Michigan |
Stat3 protein degraders
|
|
US20220177978A1
(en)
|
2019-04-02 |
2022-06-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting and preventing cancer in patients having premalignant lesions
|
|
CN113891709A
(zh)
*
|
2019-04-02 |
2022-01-04 |
德克萨斯大学系统董事会 |
用于治疗疾病的转录抑制剂和免疫检验点抑制剂的组合
|
|
WO2020208060A1
(en)
|
2019-04-09 |
2020-10-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
|
US20220220480A1
(en)
|
2019-04-17 |
2022-07-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
|
EP3725370A1
(en)
|
2019-04-19 |
2020-10-21 |
ImmunoBrain Checkpoint, Inc. |
Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease
|
|
BR112021021713A2
(pt)
|
2019-05-13 |
2022-04-19 |
Regeneron Pharma |
Método de tratamento de câncer ou inibição do crescimento de um tumor
|
|
AU2020278465A1
(en)
|
2019-05-20 |
2021-12-09 |
Dana-Farber Cancer Institute, Inc. |
Boronic ester prodrugs and uses thereof
|
|
AU2020281535A1
(en)
|
2019-05-24 |
2022-01-27 |
Merck Patent Gmbh |
Combination therapies using CDK inhibitors
|
|
AU2020291464A1
(en)
|
2019-06-12 |
2022-02-03 |
Vanderbilt University |
Amino acid transport inhibitors and the uses thereof
|
|
WO2020252336A1
(en)
|
2019-06-12 |
2020-12-17 |
Vanderbilt University |
Dibenzylamines as amino acid transport inhibitors
|
|
EP3986454A1
(en)
|
2019-06-18 |
2022-04-27 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 or anti-pd-l1 antibody
|
|
WO2020255009A2
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 antibody
|
|
MX2022000550A
(es)
|
2019-07-16 |
2022-02-10 |
Univ Michigan Regents |
Imidazopirimidinas como inhibidores de eed y uso de estas.
|
|
BR112022002013A2
(pt)
*
|
2019-08-02 |
2022-03-29 |
Akeso Pharmaceuticals Inc |
Anticorpo biespecífico anti-ctla4/anti-pd-1 e uso do mesmo
|
|
JP2022542437A
(ja)
|
2019-08-02 |
2022-10-03 |
ランティオペプ ベスローテン ヴェンノーツハップ |
癌の処置に用いるアンジオテンシン２型（ａｔ２）受容体アゴニスト
|
|
CN114127121A
(zh)
|
2019-08-12 |
2022-03-01 |
北京恩瑞尼生物科技股份有限公司 |
用于通过cd39表达细胞的adcc靶向促进和增强t细胞介导的免疫反应的方法和组合物
|
|
GB201912107D0
(en)
|
2019-08-22 |
2019-10-09 |
Amazentis Sa |
Combination
|
|
WO2021041532A1
(en)
|
2019-08-26 |
2021-03-04 |
Dana-Farber Cancer Institute, Inc. |
Use of heparin to promote type 1 interferon signaling
|
|
WO2021041664A1
(en)
|
2019-08-27 |
2021-03-04 |
The Regents Of The University Of Michigan |
Cereblon e3 ligase inhibitors
|
|
AU2020335928A1
(en)
|
2019-08-30 |
2022-02-17 |
Agenus Inc. |
Anti-CD96 antibodies and methods of use thereof
|
|
AU2020351122A1
(en)
|
2019-09-16 |
2022-02-17 |
Surface Oncology, Inc. |
Anti-CD39 antibody compositions and methods
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與ｅｎｔｐｄ２抗體之組合療法
|
|
HUE067160T2
(hu)
|
2019-09-18 |
2024-10-28 |
Lamkap Bio Alpha AG |
Bispecifikus antitestek CEACAM5 és CD3 ellen
|
|
WO2021053559A1
(en)
|
2019-09-18 |
2021-03-25 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
JOP20220068A1
(ar)
|
2019-09-18 |
2023-01-30 |
Novartis Ag |
بروتينات اندماج nkg2d واستخداماتها
|
|
US20220380368A1
(en)
|
2019-09-19 |
2022-12-01 |
The Regents Of The University Of Michigan |
Spirocyclic androgen receptor protein degraders
|
|
EP4034559A1
(en)
|
2019-09-25 |
2022-08-03 |
Surface Oncology, Inc. |
Anti-il-27 antibodies and uses thereof
|
|
CA3155341A1
(en)
|
2019-09-25 |
2021-04-01 |
Seagen Inc. |
Combination anti-cd30 adc, anti-pd-1 and chemotherapeutic for treatment of hematopoietic cancers
|
|
AU2020353055B2
(en)
|
2019-09-26 |
2024-03-07 |
Gilead Sciences, Inc. |
Antiviral pyrazolopyridinone compounds
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
CA3151322A1
(en)
|
2019-10-01 |
2021-04-08 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
|
CA3157024A1
(en)
|
2019-10-03 |
2021-04-08 |
Xencor, Inc. |
Targeted il-12 heterodimeric fc-fusion proteins
|
|
US20220363776A1
(en)
|
2019-10-04 |
2022-11-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
EP4058465A1
(en)
|
2019-11-14 |
2022-09-21 |
Cohbar Inc. |
Cxcr4 antagonist peptides
|
|
CA3157613A1
(en)
*
|
2019-11-20 |
2021-05-27 |
Gi Cell, Inc. |
Medium composition for culturing t cells and method for culturing t cells using same
|
|
WO2021108025A1
(en)
|
2019-11-26 |
2021-06-03 |
Massachusetts Institute Of Technology |
Cell-based cancer vaccines and cancer therapies
|
|
US11975026B2
(en)
|
2019-11-26 |
2024-05-07 |
Novartis Ag |
CD19 and CD22 chimeric antigen receptors and uses thereof
|
|
GB201917254D0
(en)
|
2019-11-27 |
2020-01-08 |
Adc Therapeutics Sa |
Combination therapy
|
|
EP3831849A1
(en)
|
2019-12-02 |
2021-06-09 |
LamKap Bio beta AG |
Bispecific antibodies against ceacam5 and cd47
|
|
WO2021113777A2
(en)
|
2019-12-04 |
2021-06-10 |
Orna Therapeutics, Inc. |
Circular rna compositions and methods
|
|
US11897950B2
(en)
|
2019-12-06 |
2024-02-13 |
Augusta University Research Institute, Inc. |
Osteopontin monoclonal antibodies
|
|
TW202133887A
(zh)
|
2019-12-09 |
2021-09-16 |
美商西健公司 |
使用liv1-adc及pd-1拮抗劑之組合療法
|
|
TW202135858A
(zh)
|
2019-12-20 |
2021-10-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體和檢查點抑制劑用於治療增殖性疾病之用途
|
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
CN111110655B
(zh)
*
|
2020-01-20 |
2020-12-25 |
山东大学 |
一种纳米复合物及其制备方法和应用
|
|
MX2022009100A
(es)
|
2020-01-28 |
2022-08-18 |
Genentech Inc |
Proteinas de fusion fc heterodimericas il15/il15r alfa para el tratamiento de cancer.
|
|
CA3168923A1
(en)
|
2020-01-30 |
2021-08-05 |
ONA Therapeutics S.L. |
Combination therapy for treatment of cancer and cancer metastasis
|
|
WO2021171264A1
(en)
|
2020-02-28 |
2021-09-02 |
Novartis Ag |
Dosing of a bispecific antibody that binds cd123 and cd3
|
|
KR20220151195A
(ko)
|
2020-03-06 |
2022-11-14 |
오엔에이 테라퓨틱스 에스.엘. |
항-cd36 항체 및 암을 치료하기 위한 이의 용도
|
|
MX2022011677A
(es)
|
2020-03-20 |
2023-01-11 |
Orna Therapeutics Inc |
Composiciones y métodos de arn circular.
|
|
WO2021195481A1
(en)
|
2020-03-26 |
2021-09-30 |
The Regents Of The University Of Michigan |
Small molecule stat protein degraders
|
|
BR112022020333A2
(pt)
|
2020-04-10 |
2022-11-22 |
Juno Therapeutics Inc |
Métodos e usos relacionados à terapia celular projetada com um receptor de antígeno quimérico que alveja o antígeno de maturação de células b
|
|
US20230181756A1
(en)
|
2020-04-30 |
2023-06-15 |
Novartis Ag |
Ccr7 antibody drug conjugates for treating cancer
|
|
WO2021222544A1
(en)
|
2020-05-01 |
2021-11-04 |
Ngm Biopharmaceuticals, Inc. |
Ilt-binding agents and methods of use thereof
|
|
IL298019A
(en)
|
2020-05-13 |
2023-01-01 |
Massachusetts Inst Technology |
Compositions of polymeric microdevices and their use in cancer immunotherapy
|
|
TW202210098A
(zh)
|
2020-05-26 |
2022-03-16 |
美商再生元醫藥公司 |
通過投予pd-1抑制劑治療子宮頸癌的方法
|
|
CA3184802A1
(en)
|
2020-05-26 |
2021-12-02 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) polypeptides and uses thereof for vaccine purposes
|
|
EP4157319A1
(en)
|
2020-05-28 |
2023-04-05 |
Modernatx, Inc. |
Use of mrnas encoding ox40l, il-23 and il-36gamma for treating cancer
|
|
US11767353B2
(en)
|
2020-06-05 |
2023-09-26 |
Theraly Fibrosis, Inc. |
Trail compositions with reduced immunogenicity
|
|
KR20230024967A
(ko)
|
2020-06-11 |
2023-02-21 |
노파르티스 아게 |
Zbtb32 억제제 및 이의 용도
|
|
TW202214857A
(zh)
|
2020-06-19 |
2022-04-16 |
法商昂席歐公司 |
新型結合核酸分子及其用途
|
|
JP2023531676A
(ja)
|
2020-06-23 |
2023-07-25 |
ノバルティス アーゲー |
３－（１－オキソイソインドリン－２－イル）ピぺリジン－２，６－ジオン誘導体を含む投与レジメン
|
|
WO2021260675A1
(en)
|
2020-06-24 |
2021-12-30 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
|
WO2022011204A1
(en)
|
2020-07-10 |
2022-01-13 |
The Regents Of The University Of Michigan |
Small molecule androgen receptor protein degraders
|
|
US20230233690A1
(en)
|
2020-07-10 |
2023-07-27 |
The Regents Of The University Of Michigan |
Androgen receptor protein degraders
|
|
CN116134027A
(zh)
|
2020-08-03 |
2023-05-16 |
诺华股份有限公司 |
杂芳基取代的3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
|
GB2616354A
(en)
|
2020-08-26 |
2023-09-06 |
Marengo Therapeutics Inc |
Methods of detecting TRBC1 or TRBC2
|
|
JP2023540217A
(ja)
|
2020-08-26 |
2023-09-22 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
Ｐｄ－１阻害剤を投与することによりがんを処置する方法
|
|
AU2021337223A1
(en)
|
2020-09-02 |
2023-03-16 |
Msd International Gmbh |
Combination therapy of a PD-1 antagonist and an antagonist for VEGFR-2 for treating patients with cancer
|
|
AU2021337650A1
(en)
|
2020-09-03 |
2023-05-04 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer pain by administering a pd-1 inhibitor
|
|
CN116615442A
(zh)
*
|
2020-09-08 |
2023-08-18 |
优特力克斯有限公司 |
程序性细胞死亡1多肽变体
|
|
KR20230074516A
(ko)
|
2020-09-24 |
2023-05-30 |
머크 샤프 앤드 돔 엘엘씨 |
프로그램화된 사멸 수용체 1 (pd-1) 항체 및 히알루로니다제 변이체 및 그의 단편의 안정한 제제 및 그의 사용 방법
|
|
JP2023544164A
(ja)
|
2020-10-02 |
2023-10-20 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
サイトカイン放出症候群の低減を伴うがんを治療するための抗体の組合せ
|
|
CA3199095A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
EP4244253A1
(en)
|
2020-11-12 |
2023-09-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Antibodies conjugated or fused to the receptor-binding domain of the sars-cov-2 spike protein and uses thereof for vaccine purposes
|
|
WO2022101463A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of the last c-terminal residues m31/41 of zikv m ectodomain for triggering apoptotic cell death
|
|
WO2022118197A1
(en)
|
2020-12-02 |
2022-06-09 |
Pfizer Inc. |
Time to resolution of axitinib-related adverse events
|
|
EP4259149A1
(en)
|
2020-12-08 |
2023-10-18 |
Infinity Pharmaceuticals, Inc. |
Eganelisib for use in the treatment of pd-l1 negative cancer
|
|
KR20220082558A
(ko)
|
2020-12-10 |
2022-06-17 |
재단법인 의약바이오컨버젼스연구단 |
면역 증진 활성이 있는 신규 crs 단편 펩타이드 및 이의 용도
|
|
HRP20240213T1
(hr)
|
2020-12-18 |
2024-04-26 |
Lamkap Bio Beta Ag |
Bispecifična antitijela protiv ceacam5 i cd47
|
|
EP4284510A1
(en)
|
2021-01-29 |
2023-12-06 |
Novartis AG |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
WO2022165403A1
(en)
|
2021-02-01 |
2022-08-04 |
Yale University |
Chemotherapeutic bioadhesive particles with immunostimulatory molecules for cancer treatment
|
|
CN117222413A
(zh)
|
2021-02-10 |
2023-12-12 |
同润生物医药(上海)有限公司 |
治疗肿瘤的方法和组合
|
|
GB202102396D0
(en)
|
2021-02-19 |
2021-04-07 |
Adc Therapeutics Sa |
Molecular adjuvant
|
|
WO2022187419A1
(en)
|
2021-03-03 |
2022-09-09 |
The Regents Of The University Of Michigan |
Small molecule degraders of androgen receptor
|
|
US20240166647A1
(en)
|
2021-03-03 |
2024-05-23 |
The Regents Of The University Of Michigan |
Cereblon Ligands
|
|
EP4301780A1
(en)
|
2021-03-05 |
2024-01-10 |
Leadartis, S.L. |
Trimeric polypeptides and uses thereof in the treatment of cancer
|
|
IL305776A
(en)
|
2021-03-23 |
2023-11-01 |
Regeneron Pharma |
Methods of treating cancer in patients with suppression or failure of the immune system through the administration of a PD-1 inhibitor
|
|
WO2022212400A1
(en)
|
2021-03-29 |
2022-10-06 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
JP2024515591A
(ja)
|
2021-04-08 |
2024-04-10 |
マレンゴ・セラピューティクス，インコーポレーテッド |
Ｔｃｒに結合する多機能性分子およびその使用
|
|
EP4322938A1
(en)
|
2021-04-14 |
2024-02-21 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
New method to improve nk cells cytotoxicity
|
|
KR20240054417A
(ko)
|
2021-04-16 |
2024-04-25 |
노파르티스 아게 |
항체 약물 접합체 및 이의 제조 방법
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
CN117396222A
(zh)
|
2021-05-21 |
2024-01-12 |
天津立博美华基因科技有限责任公司 |
药物组合及其用途
|
|
CN117412767A
(zh)
|
2021-05-25 |
2024-01-16 |
雪绒花免疫公司 |
C-x-c基序趋化因子受体6（cxcr6）结合分子及其使用方法
|
|
CA3220191A1
(en)
|
2021-05-26 |
2022-12-01 |
Tania Crombet Ramos |
Use of therapeutic compositions for the treatment of patients with tumours of epithelial origin
|
|
WO2022254337A1
(en)
|
2021-06-01 |
2022-12-08 |
Novartis Ag |
Cd19 and cd22 chimeric antigen receptors and uses thereof
|
|
TW202313679A
(zh)
|
2021-06-03 |
2023-04-01 |
美商欣爍克斯公司 |
包含il-2接合物及pd-1拮抗劑之頭頸癌組合療法
|
|
EP4367269A1
(en)
|
2021-07-05 |
2024-05-15 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
US20230139492A1
(en)
|
2021-07-19 |
2023-05-04 |
Regeneron Pharmaceuticals, Inc. |
Combination of checkpoint inhibitors and an oncolytic virus for treating cancer
|
|
EP4377344A1
(en)
|
2021-07-30 |
2024-06-05 |
Ona Therapeutics S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
|
EP4380980A1
(en)
|
2021-08-03 |
2024-06-12 |
F. Hoffmann-La Roche AG |
Bispecific antibodies and methods of use
|
|
WO2023015198A1
(en)
|
2021-08-04 |
2023-02-09 |
Genentech, Inc. |
Il15/il15r alpha heterodimeric fc-fusion proteins for the expansion of nk cells in the treatment of solid tumours
|
|
WO2023031366A1
(en)
|
2021-09-02 |
2023-03-09 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Anti-cecam6 antibodies with reduced side-effects
|
|
CA3231180A1
(en)
|
2021-09-08 |
2023-03-16 |
Redona Therapeutics, Inc. |
Papd5 and/or papd7 inhibiting 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivatives
|
|
TW202327595A
(zh)
|
2021-10-05 |
2023-07-16 |
美商輝瑞大藥廠 |
用於治療癌症之氮雜內醯胺化合物的組合
|
|
AU2022377637A1
(en)
|
2021-10-28 |
2024-05-02 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
|
KR20240103030A
(ko)
|
2021-11-17 |
2024-07-03 |
인스티튜트 내셔날 드 라 싼테 에 드 라 리셰르셰 메디칼르 |
범용 사르베코바이러스 백신
|
|
CA3240558A1
(en)
|
2021-12-16 |
2023-06-22 |
Valerio Therapeutics |
New conjugated nucleic acid molecules and their uses
|
|
EP4452327A1
(en)
|
2021-12-20 |
2024-10-30 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and pembrolizumab
|
|
KR20240130705A
(ko)
|
2021-12-30 |
2024-08-29 |
네오이뮨텍, 인코퍼레이티드 |
Il-7 단백질 및 vegf 길항제의 조합으로 종양을 치료하는 방법
|
|
CA3242629A1
(en)
|
2022-01-07 |
2023-07-13 |
Glenn KROOG |
Methods of treating recurrent ovarian cancer with bispecific anti-muc16 x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
|
|
CN114432441B
(zh)
*
|
2022-01-11 |
2023-04-25 |
中国人民解放军陆军军医大学第一附属医院 |
一种pd-1修饰的金复合硒化铜纳米粒子及其在介导光热靶向治疗癌症方面的应用
|
|
CN118742325A
(zh)
|
2022-01-28 |
2024-10-01 |
上海岸阔医药科技有限公司 |
预防或治疗与抗肿瘤剂相关的疾病或病症的方法
|
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|
|
TW202342474A
(zh)
|
2022-02-14 |
2023-11-01 |
美商基利科學股份有限公司 |
抗病毒吡唑并吡啶酮化合物
|
|
KR20240149434A
(ko)
|
2022-02-17 |
2024-10-14 |
리제너론 파마슈티칼스 인코포레이티드 |
암을 치료하기 위한 체크포인트 저해제 및 종양용해 바이러스의 조합
|
|
KR20240150493A
(ko)
|
2022-02-21 |
2024-10-15 |
온퀄리티 파마슈티컬스 차이나 리미티드 |
화합물 및 그 용도
|
|
WO2023161453A1
(en)
|
2022-02-24 |
2023-08-31 |
Amazentis Sa |
Uses of urolithins
|
|
IL315405A
(en)
|
2022-03-17 |
2024-11-01 |
Regeneron Pharmaceuticals Inc |
Methods for treating recurrent epithelioid sarcoma using bispecific anti-MUC16 and anti-CD3 antibodies alone or in combination with anti-PD-1 antibodies
|
|
WO2023192478A1
(en)
|
2022-04-01 |
2023-10-05 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
|
WO2023196988A1
(en)
|
2022-04-07 |
2023-10-12 |
Modernatx, Inc. |
Methods of use of mrnas encoding il-12
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
WO2023224912A1
(en)
|
2022-05-16 |
2023-11-23 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating metastatic castration-resistant prostate cancer with bispecific anti-psma x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
|
|
WO2023230554A1
(en)
|
2022-05-25 |
2023-11-30 |
Pfizer Inc. |
Combination of a braf inhibitor, an egfr inhibitor, and a pd-1 antagonist for the treatment of braf v600e-mutant, msi-h/dmmr colorectal cancer
|
|
WO2023242351A1
(en)
|
2022-06-16 |
2023-12-21 |
Lamkap Bio Beta Ag |
Combination therapy of bispecific antibodies against ceacam5 and cd47 and bispecific antibodies against ceacam5 and cd3
|
|
WO2023250400A1
(en)
|
2022-06-22 |
2023-12-28 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
|
WO2024015803A2
(en)
|
2022-07-11 |
2024-01-18 |
Autonomous Therapeutics, Inc. |
Encrypted rna and methods of its use
|
|
US20240043560A1
(en)
|
2022-08-02 |
2024-02-08 |
Regeneron Pharmaceuticals, Inc. |
Methods of Treating Metastatic Castration-Resistant Prostate Cancer with Bispecific Anti-PSMA x Anti-CD28 Antibodies in Combination with Anti-PD-1 Antibodies
|
|
US20240041929A1
(en)
|
2022-08-05 |
2024-02-08 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for gprc5d and bcma
|
|
WO2024040175A1
(en)
|
2022-08-18 |
2024-02-22 |
Pulmatrix Operating Company, Inc. |
Methods for treating cancer using inhaled angiogenesis inhibitor
|
|
WO2024040264A1
(en)
|
2022-08-19 |
2024-02-22 |
Massachusetts Institute Of Technology |
Compositions and methods for targeting dendritic cell lectins
|
|
WO2024052356A1
(en)
|
2022-09-06 |
2024-03-14 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
|
WO2024076926A1
(en)
|
2022-10-03 |
2024-04-11 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer with bispecific egfr x cd28 antibodies alone or in combination with anti-pd-1 antibodies
|
|
WO2024081736A2
(en)
|
2022-10-11 |
2024-04-18 |
Yale University |
Compositions and methods of using cell-penetrating antibodies
|
|
WO2024102722A1
(en)
|
2022-11-07 |
2024-05-16 |
Neoimmunetech, Inc. |
Methods of treating a tumor with an unmethylated mgmt promoter
|
|
WO2024112867A1
(en)
|
2022-11-23 |
2024-05-30 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods of use thereof for increasing immune responses
|
|
WO2024129778A2
(en)
|
2022-12-13 |
2024-06-20 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for baff-r and cd19 and methods and uses thereof
|
|
WO2024163477A1
(en)
|
2023-01-31 |
2024-08-08 |
University Of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
WO2024192033A1
(en)
|
2023-03-13 |
2024-09-19 |
Regeneron Pharmaceuticals, Inc. |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating melanoma
|
|
WO2024215787A1
(en)
|
2023-04-11 |
2024-10-17 |
Ngm Biopharmaceuticals, Inc. |
Methods of treating osteosarcoma using lair1 binding agents and pd-1 antagonists
|
|
WO2024216028A1
(en)
|
2023-04-12 |
2024-10-17 |
Agenus Inc. |
Methods of treating cancer using an anti-ctla4 antibody and an enpp1 inhibitor
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
WO2024223299A2
(en)
|
2023-04-26 |
2024-10-31 |
Isa Pharmaceuticals B.V. |
Methods of treating cancer by administering immunogenic compositions and a pd-1 inhibitor
|