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CY1117809T1 - Ορισμενες αμινο-πυριμιδινες, συνθεσεις αυτων, και μεθοδοι για χρηση αυτων - Google Patents

Ορισμενες αμινο-πυριμιδινες, συνθεσεις αυτων, και μεθοδοι για χρηση αυτων

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Publication number
CY1117809T1
CY1117809T1 CY20161100664T CY161100664T CY1117809T1 CY 1117809 T1 CY1117809 T1 CY 1117809T1 CY 20161100664 T CY20161100664 T CY 20161100664T CY 161100664 T CY161100664 T CY 161100664T CY 1117809 T1 CY1117809 T1 CY 1117809T1
Authority
CY
Cyprus
Prior art keywords
methods
pyrimidines
compositions
certain amino
pharmaceutically acceptable
Prior art date
Application number
CY20161100664T
Other languages
English (en)
Inventor
Zhe Yang
Alex R Muci
Jeffrey Warrington
Gustave Bergnes
Bradley P Morgan
Chihyuan Chuang
Antonio Romero
Scott Collibee
Xiangping Qian
Pu-Ping Lu
Original Assignee
Cytokinetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44834530&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1117809(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cytokinetics, Inc. filed Critical Cytokinetics, Inc.
Publication of CY1117809T1 publication Critical patent/CY1117809T1/el

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    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Pulmonology (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
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  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
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Abstract

Παρεχόμενες είναι ενώσεις του Τύπου (I) ή φαρμακευτικώς αποδεκτό άλας αυτών, όπου R1, R2, R3, R4, R5, R6, R7, R8, R9, Χ και m είναι όπως ορίζονται στο παρόν. Επίσης παρεχόμενη είναι φαρμακευτικώς αποδεκτή σύνθεση περιλαμβάνουσα ένωση του Τύπου I, ή φαρμακευτικώς αποδεκτό άλας αυτής. Επίσης παρεχόμενες είναι μέθοδοι χρήσης μίας ένωσης του τύπου I, ή φαρμακευτικώς αποδεκτού άλατος αυτής.
CY20161100664T 2010-04-23 2016-07-12 Ορισμενες αμινο-πυριμιδινες, συνθεσεις αυτων, και μεθοδοι για χρηση αυτων CY1117809T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32759710P 2010-04-23 2010-04-23
US41229910P 2010-11-10 2010-11-10
PCT/US2011/033614 WO2011133888A1 (en) 2010-04-23 2011-04-22 Certain amino-pyrimidines, compositions thereof, and methods for their use

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CY1117809T1 true CY1117809T1 (el) 2017-05-17

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CY20201100347T CY1122944T1 (el) 2010-04-23 2020-04-14 Ορισμενες αμινο-πυριμιδινες, συνθεσεις αυτων, και μεθοδοι για χρηση αυτων

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AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
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US8754114B2 (en) 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
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