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AU2001266505A1 - Substituted quinazoline derivatives and their use as inhibitors - Google Patents

Substituted quinazoline derivatives and their use as inhibitors

Info

Publication number
AU2001266505A1
AU2001266505A1 AU2001266505A AU6650501A AU2001266505A1 AU 2001266505 A1 AU2001266505 A1 AU 2001266505A1 AU 2001266505 A AU2001266505 A AU 2001266505A AU 6650501 A AU6650501 A AU 6650501A AU 2001266505 A1 AU2001266505 A1 AU 2001266505A1
Authority
AU
Australia
Prior art keywords
alkyl
compound
mmol
optionally substituted
starting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001266505A
Other languages
English (en)
Inventor
Frederic Jung
Andrew Mortlock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2001266505A1 publication Critical patent/AU2001266505A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2001266505A 2000-06-28 2001-06-21 Substituted quinazoline derivatives and their use as inhibitors Abandoned AU2001266505A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00401842 2000-06-28
EP00401842 2000-06-28
PCT/SE2001/001450 WO2002000649A1 (en) 2000-06-28 2001-06-21 Substituted quinazoline derivatives and their use as inhibitors

Publications (1)

Publication Number Publication Date
AU2001266505A1 true AU2001266505A1 (en) 2002-01-08

Family

ID=8173742

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001266505A Abandoned AU2001266505A1 (en) 2000-06-28 2001-06-21 Substituted quinazoline derivatives and their use as inhibitors

Country Status (27)

Country Link
US (2) US6919338B2 (is)
EP (1) EP1299381B1 (is)
JP (1) JP2004501914A (is)
KR (1) KR20030014411A (is)
CN (1) CN1267431C (is)
AR (1) AR030432A1 (is)
AT (1) ATE394102T1 (is)
AU (1) AU2001266505A1 (is)
BG (1) BG107376A (is)
BR (1) BR0111754A (is)
CA (1) CA2412592A1 (is)
CZ (1) CZ20024120A3 (is)
DE (1) DE60133897D1 (is)
EE (1) EE200200715A (is)
ES (1) ES2305081T3 (is)
HK (1) HK1053124A1 (is)
HU (1) HUP0301236A2 (is)
IL (1) IL153246A0 (is)
IS (1) IS6656A (is)
MX (1) MXPA02011974A (is)
NO (1) NO20026010L (is)
NZ (1) NZ522696A (is)
PL (1) PL360439A1 (is)
RU (1) RU2283311C2 (is)
SK (1) SK18102002A3 (is)
WO (1) WO2002000649A1 (is)
ZA (1) ZA200209412B (is)

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CN113311166A (zh) * 2021-04-28 2021-08-27 新疆农垦科学院 一种用于绵羊早期妊娠诊断的蛋白生物标志物及其用于绵羊早期妊娠检测的方法
CN115557601A (zh) * 2022-11-08 2023-01-03 成都理工大学 生物质微球及其制备方法与应用、生物反应器、地下井

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CN113311166A (zh) * 2021-04-28 2021-08-27 新疆农垦科学院 一种用于绵羊早期妊娠诊断的蛋白生物标志物及其用于绵羊早期妊娠检测的方法
CN113311166B (zh) * 2021-04-28 2022-10-28 新疆农垦科学院 一种用于绵羊早期妊娠诊断的蛋白生物标志物及其用于绵羊早期妊娠检测的方法
CN115557601A (zh) * 2022-11-08 2023-01-03 成都理工大学 生物质微球及其制备方法与应用、生物反应器、地下井

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US6919338B2 (en) 2005-07-19
US20060046987A1 (en) 2006-03-02
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RU2283311C2 (ru) 2006-09-10
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