Nothing Special   »   [go: up one dir, main page]

ZA200205989B - Electrospun pharmaceutical compositions. - Google Patents

Electrospun pharmaceutical compositions. Download PDF

Info

Publication number
ZA200205989B
ZA200205989B ZA200205989A ZA200205989A ZA200205989B ZA 200205989 B ZA200205989 B ZA 200205989B ZA 200205989 A ZA200205989 A ZA 200205989A ZA 200205989 A ZA200205989 A ZA 200205989A ZA 200205989 B ZA200205989 B ZA 200205989B
Authority
ZA
South Africa
Prior art keywords
agent
composition according
poly
active agent
cellulose
Prior art date
Application number
ZA200205989A
Other languages
English (en)
Inventor
Francis Ignatious
John M Baldoni
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA200205989B publication Critical patent/ZA200205989B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0015—Electro-spinning characterised by the initial state of the material
    • D01D5/003—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
    • D01D5/0038—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion the fibre formed by solvent evaporation, i.e. dry electro-spinning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0015—Electro-spinning characterised by the initial state of the material
    • D01D5/0023—Electro-spinning characterised by the initial state of the material the material being a polymer melt
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00—General methods for the manufacture of artificial filaments or the like
    • D01F1/02—Addition of substances to the spinning solution or to the melt
    • D01F1/10—Other agents for modifying properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Textile Engineering (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Mechanical Engineering (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
ZA200205989A 2000-01-28 2002-07-26 Electrospun pharmaceutical compositions. ZA200205989B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17868200P 2000-01-28 2000-01-28

Publications (1)

Publication Number Publication Date
ZA200205989B true ZA200205989B (en) 2003-02-03

Family

ID=22653497

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200205989A ZA200205989B (en) 2000-01-28 2002-07-26 Electrospun pharmaceutical compositions.

Country Status (18)

Country Link
EP (1) EP1251829A4 (de)
JP (1) JP2003521493A (de)
KR (1) KR100806412B1 (de)
CN (1) CN1223340C (de)
AR (1) AR028204A1 (de)
AU (1) AU772830B2 (de)
BR (1) BR0107869A (de)
CA (1) CA2396640A1 (de)
HU (1) HUP0301130A3 (de)
IL (1) IL150642A0 (de)
MX (1) MXPA02007298A (de)
MY (1) MY129356A (de)
NO (1) NO20023338L (de)
NZ (1) NZ519992A (de)
PL (1) PL356924A1 (de)
TW (1) TWI289061B (de)
WO (1) WO2001054667A1 (de)
ZA (1) ZA200205989B (de)

Families Citing this family (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9910505D0 (en) 1999-05-06 1999-07-07 Electrosols Ltd A method and apparatus for manufacturing consumable tablets
CA2464092C (en) * 2000-10-18 2013-03-12 Virginia Commonwealth University Intellectual Property Foundation Electroprocessing in drug delivery and cell encapsulation
JP2010163435A (ja) * 2000-11-17 2010-07-29 Virginia Commonwealth Univ Intellectual Property Foundation 電気処理されたコラーゲン
WO2002040242A1 (en) * 2000-11-17 2002-05-23 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen
AU2002242929A1 (en) * 2001-03-20 2002-10-03 Nicast Ltd. Polymer fiber tubular structure having improved kinking resistance
US6685956B2 (en) * 2001-05-16 2004-02-03 The Research Foundation At State University Of New York Biodegradable and/or bioabsorbable fibrous articles and methods for using the articles for medical applications
GB0123951D0 (en) * 2001-10-05 2001-11-28 Glaxo Group Ltd Therapies for treating respiratory diseases
WO2003063833A1 (en) 2002-02-01 2003-08-07 Pfizer Products Inc. Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
KR100549140B1 (ko) 2002-03-26 2006-02-03 이 아이 듀폰 디 네모아 앤드 캄파니 일렉트로-브로운 방사법에 의한 초극세 나노섬유 웹제조방법
US7765647B2 (en) 2002-04-04 2010-08-03 The University Of Akron Non-woven fiber assemblies
US8367570B2 (en) 2002-04-04 2013-02-05 The University Of Akron Mechanically strong absorbent non-woven fibrous mats
WO2003087443A1 (en) * 2002-04-11 2003-10-23 Secant Medical, Inc. Covering process using electrospinning of very small fibers
TW200410714A (en) * 2002-08-07 2004-07-01 Smithkline Beecham Corp Electrospun amorphous pharmaceutical compositions
US20060083784A1 (en) * 2002-08-07 2006-04-20 Smithkline Beecham Corporation Amorphous pharmaceutical compositions
US7842780B2 (en) 2003-01-07 2010-11-30 Trustees Of Tufts College Silk fibroin materials and use thereof
JP2007501218A (ja) 2003-08-04 2007-01-25 ファイザー・プロダクツ・インク 非晶質薬物の吸着物および親油性ミクロ相形成物質の医薬組成物
CA2548376A1 (en) 2003-12-31 2005-07-21 Pfizer Products Inc. Solid compositions of low-solubility drugs and poloxamers
JP4526851B2 (ja) * 2004-03-31 2010-08-18 明彦 谷岡 多糖類のナノスケールの繊維および成形体
WO2006006746A1 (en) * 2004-07-09 2006-01-19 Hak-Yong Kim Polymer particles, and a method for manufacturing the same
CN100577720C (zh) * 2005-03-21 2010-01-06 中国科学院化学研究所 可生物降解及吸收的聚合物纳米纤维膜材料及制法和用途
JP2006299459A (ja) * 2005-04-20 2006-11-02 National Institute For Materials Science 生分解性高分子不織布チューブの製造方法
CN1300393C (zh) * 2005-07-01 2007-02-14 中国科学院长春应用化学研究所 超细纤维药物剂型的乳液电纺丝制备方法
US20090107495A1 (en) * 2005-07-21 2009-04-30 National Institute For Materials Science Device for inhalation of medicine
JP4787585B2 (ja) * 2005-09-29 2011-10-05 帝人株式会社 静電紡糸法による繊維構造体の製造方法
CN100556399C (zh) * 2005-12-23 2009-11-04 中国科学院广州化学研究所 一种肠靶向型药物控释纤维及其制备方法
US8367112B2 (en) 2006-02-28 2013-02-05 Alkermes Pharma Ireland Limited Nanoparticulate carverdilol formulations
KR100824719B1 (ko) * 2006-09-04 2008-04-24 주식회사 아모메디 전분함유 나노섬유 부직포로 이루어진 생분해성 식품포장재 및 그 제조방법
CA2719637C (en) * 2008-03-27 2014-10-28 Agigma, Inc. Methods and compositions for the delivery of agents
BRPI0910892B1 (pt) 2008-04-16 2017-02-14 Procter & Gamble composição não espumante para cuidados pessoais sob a forma de artigo
JP2011530491A (ja) 2008-08-08 2011-12-22 ビーエーエスエフ ソシエタス・ヨーロピア バイオポリマーに基づいた活性物質含有連続繊維層、その使用、およびその生産のための方法
WO2010015709A2 (de) 2008-08-08 2010-02-11 Basf Se Wirkstoffhaltige fasernflächengebilde mit einstellbarer wirkstofffreisetzung, ihre anwendungen und verfahren zu ihrer herstellung
CN101721751B (zh) * 2008-10-10 2013-01-02 张阳德 负载了缓释细胞生长因子的具有内核的中空二氧化硅球的人体组织工程支架及其制法和用途
US20100291182A1 (en) * 2009-01-21 2010-11-18 Arsenal Medical, Inc. Drug-Loaded Fibers
KR101065255B1 (ko) * 2009-02-13 2011-09-16 김근형 생분해성 폴리머의 전기방사를 이용한 신규 약물 전달 시스템
CN101559242B (zh) * 2009-05-22 2015-07-29 广州迈普再生医学科技有限公司 一种可同时作为药物缓释体系的纳米人工硬脑膜及其制备方法
WO2011029777A1 (de) 2009-09-11 2011-03-17 Basf Se Verfahren zur herstellung von beschichteten polymerfasern
US9295859B2 (en) 2009-12-08 2016-03-29 The Procter & Gamble Company Porous, dissolvable solid substrate and surface resident coating comprising matrix microspheres
EP2536386A1 (de) 2010-02-16 2012-12-26 The Procter & Gamble Company Poröses, lösliches feststoffsubstrat und oberflächenhaftende beschichtung mit einem zink-pyrithion
CN101816627B (zh) * 2010-04-16 2012-03-07 浙江大学 一种协同治疗型多物质缓释滴眼剂及制备方法
CN103025929B (zh) 2010-07-02 2015-11-25 宝洁公司 包含活性剂的长丝、非织造纤维网和制备它们的方法
MX2012015072A (es) 2010-07-02 2013-02-07 Procter & Gamble Articulo con estructura soluble de trama fibrosa que comprende agentes activos.
JP5540107B2 (ja) 2010-07-02 2014-07-02 ザ プロクター アンド ギャンブル カンパニー 不織布ウェブからフィルムを作製する方法
CN102970987A (zh) 2010-07-02 2013-03-13 宝洁公司 通过施用包含长丝的个人保健制品来递送保健活性物质的方法
US20180163325A1 (en) 2016-12-09 2018-06-14 Robert Wayne Glenn, Jr. Dissolvable fibrous web structure article comprising active agents
RU2640933C1 (ru) * 2010-07-02 2018-01-12 Дзе Проктер Энд Гэмбл Компани Филаменты, содержащие пригодные для перорального введения активные компоненты, нетканые полотна и способы их изготовления
CN102971453B (zh) * 2010-07-02 2015-08-12 宝洁公司 包含非香料活性剂的长丝、非织造纤维网和制备它们的方法
RU2553294C2 (ru) 2010-07-02 2015-06-10 Дзе Проктер Энд Гэмбл Компани Материал в виде полотна и способ его изготовления
CA2803382C (en) 2010-07-02 2015-03-31 The Procter & Gamble Company Method for delivering an active agent
CN101915797B (zh) * 2010-07-27 2011-09-28 北京师范大学 一种静电纺丝固定化漆酶电极的制备方法
CN103338756B (zh) * 2010-11-26 2016-03-02 约翰内斯堡金山大学 药物剂型
WO2012084427A1 (en) 2010-12-22 2012-06-28 Unilever Nv Compositions comprising structured non-aqueous liquid phase
WO2012084441A1 (en) 2010-12-22 2012-06-28 Unilever Nv Compositions in the form of fibres
CZ303244B6 (cs) 2011-01-17 2012-06-13 Elmarco S.R.O. Nosic pro oromukosální, zejména pro sublingvální aplikaci fyziologicky aktivních látek
CN102251317B (zh) * 2011-05-18 2013-01-16 东华大学 一种药物释放可控的电纺纤维的制备方法
WO2013124869A2 (en) * 2012-02-21 2013-08-29 Amrita Vishwa Vidyapeetham University The art, method,manner process and system of fibrous bio-degradable polymeric wafers for the local delivery of therapeutic agents in combinations
CN102631715A (zh) * 2012-05-04 2012-08-15 江南大学 一种抗凝血纳米纤维膜的制备方法
CN102670483B (zh) * 2012-05-09 2014-04-02 上海交通大学 一种用于高血脂症治疗的静电纺丝纤维膜制剂及其制备方法
CN102697727B (zh) * 2012-06-12 2014-01-08 东华大学 一种利用静电纺丝技术制备自组装酮洛芬脂质体的方法
KR101454360B1 (ko) 2012-08-31 2014-10-24 서울대학교산학협력단 파에도닥틸룸 트리코르누툼 추출물을 함유하는 젤라틴 나노섬유 지지체 및 이를 이용한 창상피복재
WO2014059252A2 (en) 2012-10-12 2014-04-17 The Procter & Gamble Company Personal care composition in the form of a dissolvable article
CZ308409B6 (cs) * 2013-02-26 2020-08-05 Elmarco S.R.O. Přípravek pro aplikaci alespoň jedné biologicky a/nebo farmaceuticky aktivní látky
US9775917B2 (en) 2013-03-12 2017-10-03 Active Fibres Limited Nanofibre and bioactive compositions and related methods
EP2813212A1 (de) 2013-06-10 2014-12-17 Zentiva, a.s. Arzneimittel-Formulierung, einsetzend API in Nanofasern
US10202636B2 (en) * 2013-12-24 2019-02-12 General Electric Company Electrospun fibers for protein stabilization and storage
WO2015164227A2 (en) 2014-04-22 2015-10-29 The Procter & Gamble Company Compositions in the form of dissolvable solid structures
US9861558B2 (en) 2014-05-05 2018-01-09 The Procter & Gamble Company Methods of forming an aqueous treatment liquor by dissolving a porous solid with a benefit agent coating
US9877899B2 (en) 2014-05-05 2018-01-30 The Procter & Gamble Company Consumer product comprising a fibrous web structure with a silicone conditioning agent coating
US9937111B2 (en) 2014-05-05 2018-04-10 The Procter & Gamble Company Consumer product comprising a fibrous web solid structure with a silicone conditioning agent coating
US9827173B2 (en) 2014-05-05 2017-11-28 The Procter & Gamble Company Porous dissolvable solid structure with two benefit agents and methods of forming an aqueous treatment liquor therefrom
US9861559B2 (en) 2014-05-05 2018-01-09 The Procter & Gamble Company Consumer product comprising a porous, dissolvable, fibrous web solid structure with a silicone coating
US9867762B2 (en) 2014-05-05 2018-01-16 The Procter & Gamble Company Consumer product comprising a porous dissolvable solid structure and silicone conditioning agent coating
ES2763524T3 (es) * 2014-06-10 2020-05-29 Afyx Therapeutics As Composiciones que comprenden fibras obtenidas electrohidrodinámicamente para la administración de dosis específicas de una sustancia activa a la piel o la mucosa
CN105362269A (zh) * 2014-09-01 2016-03-02 天津药物研究院 一种含蔗糖的罗氟司特片及其制备方法
SG11201707988YA (en) * 2015-03-31 2017-10-30 Orthorebirth Co Ltd Method for manufacturing drug-containing biodegradable fiber material by electrospinning
BR112018000399A2 (pt) * 2015-07-07 2018-09-11 Nat Univ Singapore método para preparar um produto polimérico, produto polimérico, produto polimérico para cultivar células ou tecidos e solução de revestimento polimérico
CN105327357B (zh) * 2015-10-14 2019-01-11 北京科技大学 一种邻苯二酚修饰的透明质酸的载药系统及其制备方法
AU2016358266B2 (en) * 2015-11-19 2018-06-21 Afyx Therapeutics A/S A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site
AU2017211684B2 (en) * 2016-01-27 2022-10-06 Instar Technologies A.S. Oromucosal nanofiber carriers for therapeutic treatment
CN105727358B (zh) * 2016-02-23 2019-01-22 广西易得佳医疗器械有限公司 载药生物高分子复合纳米纤维膜及其制备方法
CN105663025A (zh) * 2016-02-29 2016-06-15 浙江工业大学 一种含药微丝及其制备方法
JP7162014B2 (ja) 2017-01-23 2022-10-27 アフリックス セラピューティクス アー／エス 電界紡糸繊維に基づく２層生成物の製作方法
CN110290783A (zh) 2017-01-23 2019-09-27 阿费克斯疗法有限公司 用于制备具有高含量生物粘附物质的电纺纤维的方法
JP7028877B2 (ja) 2017-01-27 2022-03-02 ザ プロクター アンド ギャンブル カンパニー 溶解性固形構造体形態の組成物
WO2018140675A1 (en) 2017-01-27 2018-08-02 The Procter & Gamble Company Compositions in the form of dissolvable solid structures comprising effervescent agglomerated particles
CN110650723A (zh) 2017-05-16 2020-01-03 宝洁公司 可溶性固体结构形式的调理毛发护理组合物
CN107447366A (zh) * 2017-08-03 2017-12-08 东华大学 一种pH敏感载药缓释纳米纤维膜及其制备方法和应用
WO2019147532A1 (en) 2018-01-26 2019-08-01 The Procter & Gamble Company Water-soluble unit dose articles comprising perfume
JP7127135B2 (ja) 2018-01-26 2022-08-29 ザ プロクター アンド ギャンブル カンパニー 水溶性物品及び関連プロセス
WO2019147534A1 (en) 2018-01-26 2019-08-01 The Procter & Gamble Company Water-soluble unit dose articles comprising perfume
CN111556891B (zh) 2018-01-26 2021-11-05 宝洁公司 包含酶的水溶性单位剂量制品
WO2019168829A1 (en) 2018-02-27 2019-09-06 The Procter & Gamble Company A consumer product comprising a flat package containing unit dose articles
JP7121944B2 (ja) * 2018-05-07 2022-08-19 国立大学法人信州大学 ナノ繊維及びその製造方法
JP1629688S (de) 2018-07-16 2019-04-15
US10982176B2 (en) 2018-07-27 2021-04-20 The Procter & Gamble Company Process of laundering fabrics using a water-soluble unit dose article
US11666514B2 (en) 2018-09-21 2023-06-06 The Procter & Gamble Company Fibrous structures containing polymer matrix particles with perfume ingredients
WO2020159860A1 (en) 2019-01-28 2020-08-06 The Procter & Gamble Company Recycleable, renewable, or biodegradable package
EP3712237A1 (de) 2019-03-19 2020-09-23 The Procter & Gamble Company Faserige wasserlösliche einmal-dosierartikel mit wasserlöslichen faserstrukturen
EP3942008A1 (de) 2019-03-19 2022-01-26 The Procter & Gamble Company Verfahren zur verminderung von schlechten gerüchen auf gewebe
JP7381613B2 (ja) 2019-06-28 2023-11-15 ザ プロクター アンド ギャンブル カンパニー アニオン性界面活性剤を含有する溶解性固体繊維性物品
CN114025738A (zh) 2019-07-03 2022-02-08 宝洁公司 包含阳离子表面活性剂和可溶性酸的纤维结构
USD939359S1 (en) 2019-10-01 2021-12-28 The Procter And Gamble Plaza Packaging for a single dose personal care product
CN114555483B (zh) 2019-10-14 2024-04-26 宝洁公司 含有固体制品的可生物降解的和/或家庭可堆肥的小袋
CN114727933B (zh) 2019-11-20 2024-03-08 宝洁公司 多孔可溶性固体结构体
CN114929182B (zh) 2019-12-01 2024-05-28 宝洁公司 具有含有苯甲酸钠和二醇和/或甘油酯的防腐体系的毛发调理剂组合物
KR20220134026A (ko) * 2020-02-13 2022-10-05 바켈 에스.알.엘. 천연 고분자 전기 방사 방법
IT202000002833A1 (it) * 2020-02-13 2021-08-13 Bakel S R L Procedimento di elettrofilatura
USD962050S1 (en) 2020-03-20 2022-08-30 The Procter And Gamble Company Primary package for a solid, single dose beauty care composition
USD941051S1 (en) 2020-03-20 2022-01-18 The Procter And Gamble Company Shower hanger
USD965440S1 (en) 2020-06-29 2022-10-04 The Procter And Gamble Company Package
EP4188554A1 (de) 2020-07-31 2023-06-07 The Procter & Gamble Company Wasserlöslicher faserbeutel mit perlen zur haarpflege
JP7513835B2 (ja) 2020-08-11 2024-07-09 ザ プロクター アンド ギャンブル カンパニー ブラシシルバリネートエシレートを含有する低粘度ヘアコンディショナー組成物
CN116472021A (zh) 2020-08-11 2023-07-21 宝洁公司 含有芸苔油醇缬氨酸酯乙磺酸盐的清洁冲洗毛发调理剂组合物
EP4196233A1 (de) 2020-08-11 2023-06-21 The Procter & Gamble Company Feuchtigkeitsspendende haarpflegezusammensetzungen mit brassicylvalinat-esylat
MX2023005792A (es) 2020-12-01 2023-05-29 Procter & Gamble Composiciones acuosas acondicionadoras de cabello que contienen activos anticaspa solubilizados.
USD1045064S1 (en) 2020-12-17 2024-10-01 The Procter & Gamble Company Single-dose dissolvable personal care unit
CN113041230B (zh) * 2021-03-23 2022-06-24 浙江尖峰健康科技有限公司 一种软胶囊的囊皮及由其制备的软胶囊
KR102653460B1 (ko) * 2021-09-01 2024-03-29 한남대학교 산학협력단 콜라겐과 레시틴을 포함하는 분해도 조절이 가능한 스타치 나노섬유의 제조방법
JPWO2023145886A1 (de) * 2022-01-31 2023-08-03
CN114808184A (zh) * 2022-03-11 2022-07-29 深圳市法鑫忠信新材料有限公司 一种长效驱蚊的静电纺丝纤维及其制备方法和应用
CN115887422B (zh) * 2022-12-31 2024-06-07 兰州交通大学 一种高乌甲素膝骨关节镇痛缓释贴及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1527592A (en) * 1974-08-05 1978-10-04 Ici Ltd Wound dressing
US4855326A (en) * 1987-04-20 1989-08-08 Fuisz Pharmaceutical Ltd. Rapidly dissoluble medicinal dosage unit and method of manufacture
US5567439A (en) * 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)
US5736152A (en) * 1995-10-27 1998-04-07 Atrix Laboratories, Inc. Non-polymeric sustained release delivery system
US5980941A (en) * 1997-08-20 1999-11-09 Fuisz Technologies Ltd. Self-binding shearform compositions
US5869098A (en) * 1997-08-20 1999-02-09 Fuisz Technologies Ltd. Fast-dissolving comestible units formed under high-speed/high-pressure conditions
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor

Also Published As

Publication number Publication date
KR20020082212A (ko) 2002-10-30
CN1396823A (zh) 2003-02-12
NO20023338D0 (no) 2002-07-11
KR100806412B1 (ko) 2008-02-21
BR0107869A (pt) 2002-11-05
NO20023338L (no) 2002-09-03
HUP0301130A3 (en) 2006-07-28
AU3113401A (en) 2001-08-07
HUP0301130A2 (hu) 2003-09-29
CN1223340C (zh) 2005-10-19
JP2003521493A (ja) 2003-07-15
NZ519992A (en) 2004-04-30
EP1251829A1 (de) 2002-10-30
IL150642A0 (en) 2003-02-12
MY129356A (en) 2007-03-30
EP1251829A4 (de) 2009-05-06
PL356924A1 (en) 2004-07-12
TWI289061B (en) 2007-11-01
CA2396640A1 (en) 2001-08-02
AR028204A1 (es) 2003-04-30
AU772830B2 (en) 2004-05-06
WO2001054667A1 (en) 2001-08-02
MXPA02007298A (es) 2002-12-09

Similar Documents

Publication Publication Date Title
AU772830B2 (en) Electrospun pharmaceutical compositions
US20030017208A1 (en) Electrospun pharmaceutical compositions
AU2003258120B2 (en) Electrospun amorphous pharmaceutical compositions
AU2004202461B2 (en) Electrospun pharmaceutical compositions
US20060083784A1 (en) Amorphous pharmaceutical compositions
Liu et al. Recent advances in electrospun for drug delivery purpose
Shadambikar et al. Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology
US20120148493A1 (en) Composite Materials Loaded with Therapeutic and Diagnostic Agents Comprising Polymer Nanoparticles and Polymer Fibers
Shams et al. Core/shell microencapsulation of indomethacin/paracetamol by co-axial electrohydrodynamic atomization
CN114748428A (zh) 一种高载药量的盐酸卡利拉嗪长效缓释微球及其制备方法
CN114681406B (zh) 一种卡利拉嗪长效缓释微球及其制备方法
Pisani et al. Tableted hydrophilic electrospun nanofibers to promote meloxicam dissolution rate
Bitay et al. Preparation and characterization of lapatinib-loaded PVP nanofiber amorphous solid dispersion by electrospinning.
CN105919975B (zh) 一种莽草酸核壳结构纳米制剂及其制备方法
CN111450078A (zh) 一种静电纺丝包载纳米颗粒的药物制剂及其制备和应用
MODICA DE MOHAC Novel Drug Delivery System for Treatment-Resistant Schizophrenia
Pinarbasli et al. Prospects of Nanomedicine with Nanocrystal Technology
Aravind Ram et al. Development and characterization of glipizide-loaded biodegradable nanoparticles by solvent displacement technique
Barichello et al. Agatonovic-Kustrin, S., V. Wu, T. Rades, D. Saville, IG Tucker, Powder diffractometric assay of two polymorphic forms of ranitidine hydrochloride 184, 107 Antos-Bielska, M., see Grzybowski, J. 184, 173 Antos-Bielska, M., see Grzybowski, J. 184, 179