HUP0003164A2 - A Helicobacter pylori FlgE polipeptidet tartalmazó vakcinakészítmények - Google Patents
A Helicobacter pylori FlgE polipeptidet tartalmazó vakcinakészítményekInfo
- Publication number
- HUP0003164A2 HUP0003164A2 HU0003164A HUP0003164A HUP0003164A2 HU P0003164 A2 HUP0003164 A2 HU P0003164A2 HU 0003164 A HU0003164 A HU 0003164A HU P0003164 A HUP0003164 A HU P0003164A HU P0003164 A2 HUP0003164 A2 HU P0003164A2
- Authority
- HU
- Hungary
- Prior art keywords
- helicobacter pylori
- vaccine compositions
- polypeptide
- subject
- polypeptides
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 241000590002 Helicobacter pylori Species 0.000 title abstract 2
- 229940037467 helicobacter pylori Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 3
- 206010019375 Helicobacter infections Diseases 0.000 abstract 2
- 102000009016 Cholera Toxin Human genes 0.000 abstract 1
- 108010049048 Cholera Toxin Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56922—Campylobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/205—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Campylobacter (G)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A találmány tárgyát olyan polipeptidek és vakcinakészítmények képezik,amelyek Helicobacter pylori fertőzéssel szemben emlősben védőimmunválaszt indukálnak. A találmány tárgyát képezi továbbáHelicobacter pylori polipeptidek alkalmazása Helicobacter pylorifertőzések kezelésére, megelőzésére vagy diagnózisára szolgálókészítmények előállításában. Nevezett vakcinakészítmények H. pyloriFlgE polipeptid - vagy annak funkcionálisan ekvivalens antigenitástmegtartó módosított formája - mellett gyógyszerészetileg elfogadhatóhordozót, hígítószert vagy adott esetben adjuvánst - koleratoxint -tartalmaznak. Ó
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9702242A SE9702242D0 (sv) | 1997-06-12 | 1997-06-12 | Vaccine compositions V |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0003164A2 true HUP0003164A2 (hu) | 2000-12-28 |
| HUP0003164A3 HUP0003164A3 (en) | 2001-10-29 |
Family
ID=20407351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0003164A HUP0003164A3 (en) | 1997-06-12 | 1998-06-08 | Vaccine compositions comprising the helicobacter pylori flge polypeptide |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1009764A1 (hu) |
| JP (1) | JP2002507118A (hu) |
| KR (1) | KR20010013699A (hu) |
| CN (1) | CN1259960A (hu) |
| AR (1) | AR012896A1 (hu) |
| AU (1) | AU8048798A (hu) |
| BR (1) | BR9810026A (hu) |
| CA (1) | CA2293293A1 (hu) |
| EE (1) | EE9900566A (hu) |
| HU (1) | HUP0003164A3 (hu) |
| ID (1) | ID23052A (hu) |
| IL (1) | IL133144A0 (hu) |
| IS (1) | IS5288A (hu) |
| NO (1) | NO996132L (hu) |
| NZ (1) | NZ501427A (hu) |
| PL (1) | PL337503A1 (hu) |
| SE (1) | SE9702242D0 (hu) |
| SK (1) | SK173099A3 (hu) |
| TR (1) | TR199903060T2 (hu) |
| WO (1) | WO1998056816A1 (hu) |
| ZA (1) | ZA984696B (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104784687A (zh) * | 2015-04-27 | 2015-07-22 | 苏州大学附属第一医院 | 重组绿脓杆菌鞭毛钩蛋白FlgE的用途 |
| CN113425717B (zh) * | 2021-04-22 | 2023-06-16 | 成都欧林生物科技股份有限公司 | 一种提高口服幽门螺杆菌疫苗效力的药剂及其应用 |
| CN116535472B (zh) * | 2023-05-31 | 2024-04-30 | 四川大学华西医院 | 一种幽门螺杆菌重组蛋白抗原FlgK及其制备方法与应用 |
| CN118105473B (zh) * | 2024-04-30 | 2024-08-16 | 成都欧林生物科技股份有限公司 | 一种预防或治疗Hp感染口服免疫原性组合物及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5459041A (en) * | 1988-02-18 | 1995-10-17 | Enteric Research Laboratories, Inc. | Campylobacter pylori antigens and uses thereof for detection of Campylobacter pylori infection |
| AR003125A1 (es) * | 1995-06-01 | 1998-07-08 | Astra Ab | Antigenos bacterianos para el diagnostico de infecciones con helicobacter pylori, una molecula de adn que lo codifica, un vector, una celula huesped,procedimiento para producir el polipeptido, composiciones para vacunas adecuadas para uso terapeutico y profilactico, el uso del polipeptido en la |
-
1997
- 1997-06-12 SE SE9702242A patent/SE9702242D0/xx unknown
-
1998
- 1998-06-01 ZA ZA984696A patent/ZA984696B/xx unknown
- 1998-06-01 AR ARP980102558A patent/AR012896A1/es unknown
- 1998-06-08 SK SK1730-99A patent/SK173099A3/sk unknown
- 1998-06-08 EE EEP199900566A patent/EE9900566A/xx unknown
- 1998-06-08 EP EP98928772A patent/EP1009764A1/en not_active Withdrawn
- 1998-06-08 CA CA002293293A patent/CA2293293A1/en not_active Abandoned
- 1998-06-08 PL PL98337503A patent/PL337503A1/xx unknown
- 1998-06-08 IL IL13314498A patent/IL133144A0/xx unknown
- 1998-06-08 CN CN98806101A patent/CN1259960A/zh active Pending
- 1998-06-08 NZ NZ501427A patent/NZ501427A/xx unknown
- 1998-06-08 AU AU80487/98A patent/AU8048798A/en not_active Abandoned
- 1998-06-08 KR KR1019997011714A patent/KR20010013699A/ko not_active Application Discontinuation
- 1998-06-08 ID IDW991542A patent/ID23052A/id unknown
- 1998-06-08 TR TR1999/03060T patent/TR199903060T2/xx unknown
- 1998-06-08 HU HU0003164A patent/HUP0003164A3/hu unknown
- 1998-06-08 JP JP50228399A patent/JP2002507118A/ja active Pending
- 1998-06-08 WO PCT/SE1998/001093 patent/WO1998056816A1/en not_active Application Discontinuation
- 1998-06-08 BR BR9810026-2A patent/BR9810026A/pt not_active IP Right Cessation
-
1999
- 1999-12-08 IS IS5288A patent/IS5288A/is unknown
- 1999-12-10 NO NO996132A patent/NO996132L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO996132L (no) | 2000-01-28 |
| BR9810026A (pt) | 2000-09-19 |
| JP2002507118A (ja) | 2002-03-05 |
| NO996132D0 (no) | 1999-12-10 |
| WO1998056816A1 (en) | 1998-12-17 |
| EP1009764A1 (en) | 2000-06-21 |
| AU8048798A (en) | 1998-12-30 |
| PL337503A1 (en) | 2000-08-28 |
| CA2293293A1 (en) | 1998-12-17 |
| IS5288A (is) | 1999-12-08 |
| CN1259960A (zh) | 2000-07-12 |
| ID23052A (id) | 2000-01-20 |
| ZA984696B (en) | 1999-01-04 |
| HUP0003164A3 (en) | 2001-10-29 |
| TR199903060T2 (xx) | 2000-09-21 |
| EE9900566A (xx) | 2000-06-15 |
| SE9702242D0 (sv) | 1997-06-12 |
| SK173099A3 (en) | 2000-06-12 |
| AR012896A1 (es) | 2000-11-22 |
| KR20010013699A (ko) | 2001-02-26 |
| NZ501427A (en) | 2000-09-29 |
| IL133144A0 (en) | 2001-03-19 |
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