IL155335A0 - Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament - Google Patents

Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Info

Publication number: IL155335A0
Authority: IL; Israel
Prior art keywords: medicament; producing; production; same; crystalline monohydrate
Prior art date: 2000-10-12

Application number

IL15533501A

Other languages

English (en)

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-12

Filing date

2001-09-28

Publication date

2003-11-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL155335(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-09-28 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2003-11-23 Publication of IL155335A0 publication Critical patent/IL155335A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL15533501A 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament IL155335A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10050621		2000-10-12
PCT/EP2001/011225 WO2002030928A1 (de)	2000-10-12	2001-09-28	Kristallines monohydrat, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels

Publications (1)

Publication Number	Publication Date
IL155335A0 true IL155335A0 (en)	2003-11-23

Family

ID=7659568

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15533501A IL155335A0 (en)	2000-10-12	2001-09-28	Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament
IL155335A IL155335A (en)	2000-10-12	2003-04-10	Crystalline monohydrate of theotropium bromide, method of its formation and use in drug production

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL155335A IL155335A (en)	2000-10-12	2003-04-10	Crystalline monohydrate of theotropium bromide, method of its formation and use in drug production

Country Status (47)

Country	Link
EP (2)	EP1468998A1 (pl)
JP (1)	JP3764422B2 (pl)
KR (1)	KR100823860B1 (pl)
CN (2)	CN100519558C (pl)
AP (1)	AP1572A (pl)
AR (2)	AR034389A1 (pl)
AT (1)	ATE276253T1 (pl)
AU (2)	AU1499602A (pl)
BG (1)	BG66161B1 (pl)
BR (1)	BR0114584A (pl)
CA (1)	CA2425539C (pl)
CR (1)	CR6938A (pl)
CZ (1)	CZ301841B6 (pl)
DE (1)	DE50103666D1 (pl)
DK (1)	DK1326862T3 (pl)
DZ (1)	DZ3478A1 (pl)
EA (1)	EA004381B1 (pl)
EC (1)	ECSP034540A (pl)
EE (1)	EE04567B1 (pl)
EG (1)	EG24142A (pl)
ES (1)	ES2228965T3 (pl)
GE (1)	GEP20063905B (pl)
HK (2)	HK1060567A1 (pl)
HR (1)	HRP20030276B1 (pl)
HU (1)	HU226830B1 (pl)
IL (2)	IL155335A0 (pl)
IS (1)	IS2339B (pl)
MA (1)	MA25842A1 (pl)
ME (2)	MEP40008A (pl)
MX (1)	MXPA03003221A (pl)
MY (1)	MY126931A (pl)
NO (1)	NO328465B1 (pl)
NZ (1)	NZ525733A (pl)
OA (1)	OA12403A (pl)
PE (1)	PE20020422A1 (pl)
PL (1)	PL207870B1 (pl)
PT (1)	PT1326862E (pl)
RS (1)	RS50218B (pl)
SA (1)	SA01220412B1 (pl)
SI (1)	SI1326862T1 (pl)
SK (1)	SK287009B6 (pl)
TR (1)	TR200402579T4 (pl)
TW (1)	TW589313B (pl)
UA (1)	UA74215C2 (pl)
UY (2)	UY26962A1 (pl)
WO (1)	WO2002030928A1 (pl)
ZA (1)	ZA200302500B (pl)

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AU2002345016B2 (en) *	2001-06-22	2008-04-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Crystalline anticholinergic, method for its production, and use thereof in the production of a drug
US6608055B2 (en)	2001-06-22	2003-08-19	Boehringer Ingelheim Pharma Kg	Crystalline anticholinergic, processes for preparing it and its use for preparing a pharmaceutical composition
DE10212264A1 (de)	2002-03-20	2003-10-02	Boehringer Ingelheim Pharma	Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
US7244415B2 (en)	2002-03-28	2007-07-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations of an anhydrate
DE10214263A1 (de) *	2002-03-28	2003-10-16	Boehringer Ingelheim Pharma	HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum
US7311894B2 (en)	2002-03-28	2007-12-25	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations containing an anticholinergic
US7056916B2 (en)	2002-11-15	2006-06-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments for the treatment of chronic obstructive pulmonary disease
DE10317461A1 (de)	2003-04-16	2004-10-28	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
ME00349B (me) *	2003-11-03	2011-05-10	Boehringer Ingelheim Int	Novi kristalni anhidrat sa antiholinergij skim dejstvom
UY28590A1 (es) *	2003-11-03	2005-06-30	Boehringer Ingelheim Int	Procedimiento para la preparación de nuevas sales de tiotropio, nuevas sales de tiotropio como tales, así como las formulaciones medicamentosas que las contienen.
US7968717B2 (en)	2003-11-03	2011-06-28	Boehringer Ingelhein International Gmbh	Crystalline anhydrate with anticholinergic efficacy
EP2319844A1 (de) *	2003-11-03	2011-05-11	Boehringer Ingelheim International GmbH	Tiotropiumsalze, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittelformulierungen
DE102004016179A1 (de) *	2004-03-30	2005-10-20	Boehringer Ingelheim Pharma	Verbindungen zur Behandlung von proliferativen Prozessen
ES2380370T3 (es)	2004-04-22	2012-05-11	Boehringer Ingelheim International Gmbh	Combinaciones farmacológicas que contienen benzoxazina para el tratamiento de enfermedades de las vías respiratorias
US7220742B2 (en)	2004-05-14	2007-05-22	Boehringer Ingelheim International Gmbh	Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
DE102004024454A1 (de)	2004-05-14	2005-12-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
ATE427108T1 (de)	2004-08-11	2009-04-15	Boehringer Ingelheim Pharma	Anticholinergika enthaltende arzneimittel zur behandlung von krankheiten der ableitenden harnwege
US20060079544A1 (en) *	2004-08-13	2006-04-13	Boehringer Ingelheim International Gmbh	Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
DE102004048389A1 (de)	2004-10-01	2006-04-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
JP5566576B2 (ja) *	2004-10-21	2014-08-06	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	吸入器用ブリスタ
EP1858554A2 (en) *	2005-03-09	2007-11-28	Boehringer Ingelheim International GmbH	New pharmaceutical compositions based on anticholinergics and pde 5-inhibitors
AU2006237354B2 (en)	2005-04-21	2012-03-01	Boehringer Ingelheim International Gmbh	Dihydrothienopyrimidines for the treatment of inflammatory diseases
JP5053997B2 (ja)	2005-04-28	2012-10-24	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	炎症性疾患の治療用の新規化合物
BRPI0611091A2 (pt) *	2005-05-02	2010-08-03	Boehringer Ingelheim Int	formas cristalinas de brometo de tiotrópico
DK1881980T3 (da)	2005-05-02	2012-10-01	Boehringer Ingelheim Int	Nye krystalline former af tiotropiumbromid
EP1896026B1 (en) *	2005-06-15	2013-10-09	Boehringer Ingelheim International GmbH	Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof
DE102005030733A1 (de)	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
KR20080039974A (ko) *	2005-08-06	2008-05-07	베링거 인겔하임 인터내셔날 게엠베하	중증 지속성 천식의 치료에서 티오트로퓸 염의 용도
BRPI0614410A2 (pt)	2005-08-15	2011-03-29	Boehringer Ingelheim Int	processo para preparação de betamiméticos
US20070086957A1 (en)	2005-10-10	2007-04-19	Thierry Bouyssou	Combination of medicaments for the treatment of respiratory diseases
US7423146B2 (en)	2005-11-09	2008-09-09	Boehringer Ingelheim International Gmbh	Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
DE102005059602A1 (de) *	2005-12-14	2007-06-21	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Mikronisierung
ES2396978T5 (es) *	2005-12-19	2015-12-04	Sicor, Inc.	Forma cristalina novedosa de bromuro de tiotropio y procedimiento para la preparación de la misma
EP1966196A2 (en) *	2005-12-19	2008-09-10	Sicor, Inc.	Pure and stable tiotropium bromide
EA015353B1 (ru) *	2006-01-04	2011-06-30	Бёрингер Ингельхайм Интернациональ Гмбх	Применение солей тиотропия для лечения персистирующей астмы средней тяжести
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GB0716026D0 (en)	2007-08-16	2007-09-26	Norton Healthcare Ltd	An inhalable medicament
PL2215092T3 (pl)	2007-10-19	2012-07-31	Boehringer Ingelheim Int	Podstawione piperydyno-dihydrotienopirymidyny
EP2093219A1 (de)	2008-02-22	2009-08-26	Boehringer Ingelheim International Gmbh	Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
WO2010011813A1 (en) *	2008-07-23	2010-01-28	Alkermes, Inc.	Complex of trospium and pharmaceutical compositions thereof
JP2012512834A (ja)	2008-12-19	2012-06-07	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	炎症、喘息及びｃｏｐｄの処置のためのｃｃｒ２受容体アンタゴニストとしての環状ピリミジン−４−カルボキサミド
EP2201934A1 (en)	2008-12-23	2010-06-30	CHIESI FARMACEUTICI S.p.A.	Tiotropium aerosol formulation products with improved chemical stability
EP2403851B1 (en)	2009-03-06	2015-06-17	Mahmut Bilgic	New crystalline forms of tiotropium bromide
WO2011015883A1 (en)	2009-08-07	2011-02-10	Generics [Uk] Limited	Dichloromethane solvate of tiotropium bromide and its use
CA2768553C (en)	2009-08-07	2016-08-02	Generics [Uk] Limited	Anhydrate of tiotropium bromide
NZ599770A (en)	2009-12-17	2014-06-27	Boehringer Ingelheim Int	New ccr2 receptor antagonists and uses thereof
EP2513086B1 (en)	2009-12-17	2015-04-29	Boehringer Ingelheim International GmbH	Novel antagonists for ccr2 and uses thereof
CA2786245A1 (en)	2010-01-29	2011-08-04	Boehringer Ingelheim International Gmbh	Substituted naphthyridines and their use as syk kinase inhibitors
EP2569298B1 (en)	2010-05-12	2015-11-25	Boehringer Ingelheim International GmbH	Novel ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments
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GB201200525D0 (en)	2011-12-19	2012-02-29	Teva Branded Pharmaceutical Prod R & D Inc	An inhalable medicament
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EA025960B1 (ru)	2012-11-05	2017-02-28	Зентива, К.С.	Стабилизация сольватов тиотропия
EP2913332A1 (en) *	2014-02-27	2015-09-02	Euticals S.P.A.	Crystalline form of tiotropium bromide with lactose
CN110183440B (zh)	2014-03-19	2022-04-22	勃林格殷格翰国际有限公司	杂芳基syk抑制剂
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RU2567539C1 (ru) *	2015-02-04	2015-11-10	Индивидуальный предприниматель Михайлов Олег Ростиславович	КРИСТАЛЛИЧЕСКАЯ γ-МОДИФИКАЦИЯ (1α,2β,4β,5α,7β-7)-[(ГИДРОКСИДИ-2-ТИЕНИЛАЦЕТИЛ)ОКСИ]-9,9-ДИМЕТИЛ-3-ОКСА-9-АЗОНИАТРИЦИКЛО[3.3.1.02,4]НОНАН БРОМИДА МОНОГИДРАТА, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕЁ ОСНОВЕ
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2001
- 2001-09-28 PL PL366041A patent/PL207870B1/pl unknown
- 2001-09-28 CN CNB2005100977370A patent/CN100519558C/zh not_active Ceased
- 2001-09-28 DK DK01983510T patent/DK1326862T3/da active
- 2001-09-28 EP EP04016877A patent/EP1468998A1/de not_active Withdrawn
- 2001-09-28 DZ DZ013478A patent/DZ3478A1/fr active
- 2001-09-28 AP APAP/P/2003/002775A patent/AP1572A/en active Active
- 2001-09-28 CN CNB018171435A patent/CN1221549C/zh not_active Ceased
- 2001-09-28 CZ CZ20031025A patent/CZ301841B6/cs not_active IP Right Cessation
- 2001-09-28 WO PCT/EP2001/011225 patent/WO2002030928A1/de active IP Right Grant
- 2001-09-28 EE EEP200300171A patent/EE04567B1/xx unknown
- 2001-09-28 ME MEP-400/08A patent/MEP40008A/xx unknown
- 2001-09-28 RS YU27303A patent/RS50218B/sr unknown
- 2001-09-28 MX MXPA03003221A patent/MXPA03003221A/es active IP Right Grant
- 2001-09-28 CA CA002425539A patent/CA2425539C/en not_active Expired - Lifetime
- 2001-09-28 ME MEP-2008-400A patent/ME00243B/me unknown
- 2001-09-28 EP EP01983510A patent/EP1326862B1/de not_active Expired - Lifetime
- 2001-09-28 SK SK436-2003A patent/SK287009B6/sk not_active IP Right Cessation
- 2001-09-28 BR BR0114584-3A patent/BR0114584A/pt active Pending
- 2001-09-28 AU AU1499602A patent/AU1499602A/xx active Pending
- 2001-09-28 JP JP2002534314A patent/JP3764422B2/ja not_active Expired - Lifetime
- 2001-09-28 OA OA1200300107A patent/OA12403A/fr unknown
- 2001-09-28 PT PT01983510T patent/PT1326862E/pt unknown
- 2001-09-28 TR TR2004/02579T patent/TR200402579T4/xx unknown
- 2001-09-28 DE DE50103666T patent/DE50103666D1/de not_active Expired - Lifetime
- 2001-09-28 AU AU2002214996A patent/AU2002214996B2/en not_active Expired
- 2001-09-28 GE GE5214A patent/GEP20063905B/en unknown
- 2001-09-28 KR KR1020037005083A patent/KR100823860B1/ko active IP Right Grant
- 2001-09-28 NZ NZ525733A patent/NZ525733A/en not_active IP Right Cessation
- 2001-09-28 AT AT01983510T patent/ATE276253T1/de active
- 2001-09-28 HU HU0301022A patent/HU226830B1/hu unknown
- 2001-09-28 IL IL15533501A patent/IL155335A0/xx active IP Right Grant
- 2001-09-28 ES ES01983510T patent/ES2228965T3/es not_active Expired - Lifetime
- 2001-09-28 EA EA200300457A patent/EA004381B1/ru not_active IP Right Cessation
- 2001-09-28 UA UA2003054185A patent/UA74215C2/uk unknown
- 2001-09-28 SI SI200130219T patent/SI1326862T1/xx unknown
- 2001-10-02 SA SA01220412A patent/SA01220412B1/ar unknown
- 2001-10-09 EG EG20011058A patent/EG24142A/xx active
- 2001-10-09 TW TW090124963A patent/TW589313B/zh active
- 2001-10-10 MY MYPI20014705A patent/MY126931A/en unknown
- 2001-10-10 PE PE2001001000A patent/PE20020422A1/es active IP Right Grant
- 2001-10-10 UY UY26962A patent/UY26962A1/es not_active Application Discontinuation
- 2001-10-12 AR ARP010104782A patent/AR034389A1/es active Pending
2003
- 2003-03-26 CR CR6938A patent/CR6938A/es unknown
- 2003-03-28 BG BG107687A patent/BG66161B1/bg active Active
- 2003-03-31 ZA ZA200302500A patent/ZA200302500B/en unknown
- 2003-04-07 EC EC2003004540A patent/ECSP034540A/es unknown
- 2003-04-08 MA MA27102A patent/MA25842A1/fr unknown
- 2003-04-09 IS IS6772A patent/IS2339B/is unknown
- 2003-04-10 IL IL155335A patent/IL155335A/en unknown
- 2003-04-10 HR HR20030276A patent/HRP20030276B1/xx not_active IP Right Cessation
- 2003-04-11 NO NO20031694A patent/NO328465B1/no not_active IP Right Cessation
2004
- 2004-05-20 HK HK04103583A patent/HK1060567A1/xx not_active IP Right Cessation
2006
- 2006-06-07 HK HK06106478.2A patent/HK1086557A1/xx not_active IP Right Cessation
2008
- 2008-09-19 AR ARP080104109A patent/AR068527A2/es unknown
2013
- 2013-07-11 UY UY34901A patent/UY34901A/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
PL207870B1 (pl)	2011-02-28
ES2228965T3 (es)	2005-04-16
CN1469877A (zh)	2004-01-21
IS2339B (is)	2008-02-15
DK1326862T3 (da)	2004-11-22
EP1326862B1 (de)	2004-09-15
TR200402579T4 (tr)	2004-12-21
EA200300457A1 (ru)	2003-10-30
UA74215C2 (uk)	2005-11-15
AP2003002775A0 (en)	2003-03-31
AR034389A1 (es)	2004-02-25
ECSP034540A (es)	2003-07-25
AP1572A (en)	2006-02-13
SI1326862T1 (en)	2005-02-28
HRP20030276A2 (en)	2005-02-28
UY34901A (es)	2015-02-27
EP1326862A1 (de)	2003-07-16
CN1221549C (zh)	2005-10-05
HRP20030276B1 (en)	2006-02-28
NO328465B1 (no)	2010-02-22
BG66161B1 (bg)	2011-09-30
AU1499602A (en)	2002-04-22
HK1060567A1 (en)	2004-08-13
GEP20063905B (en)	2006-08-25
NO20031694L (no)	2003-04-11
PL366041A1 (pl)	2005-01-24
HUP0301022A3 (en)	2005-12-28
TW589313B (en)	2004-06-01
DZ3478A1 (fr)	2002-04-18
HUP0301022A2 (hu)	2003-10-28
PE20020422A1 (es)	2002-06-28
NO20031694D0 (no)	2003-04-11
NZ525733A (en)	2005-01-28
UY26962A1 (es)	2002-06-20
DE50103666D1 (de)	2004-10-21
SK4362003A3 (en)	2003-08-05
MEP40008A (en)	2011-02-10
CZ301841B6 (cs)	2010-07-07
EA004381B1 (ru)	2004-04-29
KR100823860B1 (ko)	2008-04-21
EP1468998A1 (de)	2004-10-20
ATE276253T1 (de)	2004-10-15
JP3764422B2 (ja)	2006-04-05
EE200300171A (et)	2003-06-16
SK287009B6 (sk)	2009-09-07
CA2425539C (en)	2007-04-03
KR20030042008A (ko)	2003-05-27
ZA200302500B (en)	2004-04-22
AU2002214996B2 (en)	2007-03-15
CN1733761A (zh)	2006-02-15
BR0114584A (pt)	2003-08-26
IS6772A (is)	2003-04-09
WO2002030928A1 (de)	2002-04-18
EE04567B1 (et)	2005-12-15
RS50218B (sr)	2009-07-15
ME00243B (me)	2011-05-10
PT1326862E (pt)	2004-11-30
YU27303A (sh)	2006-05-25
BG107687A (bg)	2003-09-30
HK1086557A1 (en)	2006-09-22
MY126931A (en)	2006-10-31
MXPA03003221A (es)	2004-12-03
CA2425539A1 (en)	2003-04-11
CR6938A (es)	2004-10-28
SA01220412B1 (ar)	2006-11-05
IL155335A (en)	2009-02-11
OA12403A (en)	2006-04-18
HU226830B1 (en)	2009-11-30
JP2004526668A (ja)	2004-09-02
AR068527A2 (es)	2009-11-18
MA25842A1 (fr)	2003-07-01
EG24142A (en)	2008-08-06
CN100519558C (zh)	2009-07-29

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Legal Events

Date	Code	Title	Description
2009-12-24	FF	Patent granted
2009-12-24	KB	Patent renewed