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DK1214937T3 - Terfenadincarboxylat og behandling af hudirritation - Google Patents

Terfenadincarboxylat og behandling af hudirritation

Info

Publication number
DK1214937T3
DK1214937T3 DK02006356T DK02006356T DK1214937T3 DK 1214937 T3 DK1214937 T3 DK 1214937T3 DK 02006356 T DK02006356 T DK 02006356T DK 02006356 T DK02006356 T DK 02006356T DK 1214937 T3 DK1214937 T3 DK 1214937T3
Authority
DK
Denmark
Prior art keywords
treatment
skin irritation
compound
formula
terfenadine carboxylate
Prior art date
Application number
DK02006356T
Other languages
English (en)
Inventor
Nancy M Gray
Yiwang Chen
Raymond L Woosley
James W Young
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27129882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1214937(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sepracor Inc filed Critical Sepracor Inc
Application granted granted Critical
Publication of DK1214937T3 publication Critical patent/DK1214937T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)
DK02006356T 1992-08-03 1993-08-03 Terfenadincarboxylat og behandling af hudirritation DK1214937T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92418292A 1992-08-03 1992-08-03
US92415692A 1992-08-03 1992-08-03
PCT/US1993/007260 WO1994003170A1 (en) 1992-08-03 1993-08-03 Terfenadine metabolites and their optically pure isomers for treating allergic disorders

Publications (1)

Publication Number Publication Date
DK1214937T3 true DK1214937T3 (da) 2007-09-17

Family

ID=27129882

Family Applications (3)

Application Number Title Priority Date Filing Date
DK02006356T DK1214937T3 (da) 1992-08-03 1993-08-03 Terfenadincarboxylat og behandling af hudirritation
DK93918584T DK0701443T4 (da) 1992-08-03 1993-08-03 Terfenadinmetabolitter og deres optisk rene isomerer til behandling af allergiske lidelser
DK97104837T DK0815860T3 (da) 1992-08-03 1993-08-03 Terfenadincarboxylat og behandlingen af allergiske lidelser

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK93918584T DK0701443T4 (da) 1992-08-03 1993-08-03 Terfenadinmetabolitter og deres optisk rene isomerer til behandling af allergiske lidelser
DK97104837T DK0815860T3 (da) 1992-08-03 1993-08-03 Terfenadincarboxylat og behandlingen af allergiske lidelser

Country Status (24)

Country Link
US (1) US5375693A (da)
EP (4) EP0815860B1 (da)
JP (6) JP3041954B2 (da)
KR (1) KR950702420A (da)
AT (3) ATE363283T1 (da)
AU (3) AU675240B2 (da)
BR (1) BR9306841A (da)
CA (1) CA2141572C (da)
CZ (1) CZ27495A3 (da)
DE (5) DE69316660T3 (da)
DK (3) DK1214937T3 (da)
ES (3) ES2257757T3 (da)
FI (1) FI950467A (da)
GB (1) GB2284351B (da)
GR (3) GR960300024T1 (da)
HK (1) HK1045806B (da)
HU (1) HU226242B1 (da)
NO (1) NO310644B1 (da)
PL (1) PL174373B1 (da)
PT (2) PT815860E (da)
RO (1) RO116043B1 (da)
RU (1) RU2167657C2 (da)
SK (1) SK12495A3 (da)
WO (1) WO1994003170A1 (da)

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NZ251834A (en) * 1992-05-11 1997-07-27 Merrell Dow Pharma Use of acid derivatives of terfenadine as antihistamines
DK1214937T3 (da) 1992-08-03 2007-09-17 Sepracor Inc Terfenadincarboxylat og behandling af hudirritation
US20020007068A1 (en) 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
ATE174589T1 (de) * 1993-06-24 1999-01-15 Albany Molecular Res Inc Verfahren zur herstellung von piperidinderivaten
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
EP1178041A1 (en) 1994-05-18 2002-02-06 Aventis Pharmaceuticals Inc. Process for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives
US5455049A (en) * 1995-01-04 1995-10-03 Ascent Pharmaceuticals, Inc. Terfenadine oral powder
MX9706449A (es) * 1995-02-28 1997-11-29 Hoechst Marion Roussel Inc Composicion farmaceutica para compuestos de piperidinalcanol.
GB9513972D0 (en) * 1995-07-08 1995-09-06 Merck Sharp & Dohme Pharmaceutical compositions
US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
US6355656B1 (en) 1995-12-04 2002-03-12 Celgene Corporation Phenidate drug formulations having diminished abuse potential
US5908850A (en) * 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
US6486177B2 (en) * 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US5837284A (en) * 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US5922736A (en) * 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US5733756A (en) * 1996-01-05 1998-03-31 Celgene Corporation Lactams and processes for stereoselective enrichment of lactams, amides, and esters
US6201124B1 (en) 1995-12-21 2001-03-13 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US6153754A (en) 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
ES2124167B1 (es) * 1996-06-04 1999-09-16 Espanola Prod Quimicos Nuevos derivados del bencimidazol con actividad antihistaminica.
US5925761A (en) * 1997-02-04 1999-07-20 Sepracor Inc. Synthesis of terfenadine and derivatives
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
ID22891A (id) * 1997-08-26 1999-12-16 Hoechst Marion Roussel Inc Komposisi farmasi untuk kombinasi piperidinoalkanol-dekongestan
US6194431B1 (en) * 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
DE19913862C2 (de) * 1999-03-26 2003-04-10 Forschungszentrum Juelich Gmbh Verfahren zur biokatalysierten Umsetzung schlecht wasserlöslicher Substanzen
DE10007203A1 (de) * 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US6613907B2 (en) 2000-11-08 2003-09-02 Amr Technology, Inc. Process for the production of piperidine derivatives with microorganisms
WO2002080857A2 (en) * 2001-04-09 2002-10-17 Teva Pharmaceutical Industries Ltd. Polymorphs of fexofenadine hydrochloride
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
WO2003020274A1 (en) * 2001-08-30 2003-03-13 Aventis Pharmaceuticals Inc. Treatment of atopic dermatitis
EP1474392A1 (en) * 2002-06-10 2004-11-10 Teva Pharmaceutical Industries Ltd. Polymorphic form xvi of fexofenadine hydrochloride
US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
JP4515121B2 (ja) 2004-03-15 2010-07-28 東芝テック株式会社 ワイヤドットプリンタヘッド及びワイヤドットプリンタ
JP4473021B2 (ja) 2004-03-22 2010-06-02 東芝テック株式会社 窒化層形成方法、磁気回路形成部材、アーマチュア、ワイヤドットプリンタヘッド及びワイヤドットプリンタ
US20050239830A1 (en) * 2004-04-26 2005-10-27 Vikram Khetani Methods of diminishing co-abuse potential
KR20070007196A (ko) * 2004-04-26 2007-01-12 테바 파마슈티컬 인더스트리즈 리미티드 펙소페나딘 히드로클로라이드의 결정형 및 이의 제조 방법
US7498443B2 (en) 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of carebastine
US7498345B2 (en) 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US20060148851A1 (en) * 2004-09-28 2006-07-06 Shlomit Wizel Fexofenadine crystal form and processes for its preparation thereof
US20060127421A1 (en) * 2004-12-09 2006-06-15 Celgene Corporation Treatment using D-threo methylphenidate
US8067433B2 (en) 2005-11-09 2011-11-29 Zalicus Inc. Methods, compositions, and kits for the treatment of ophthalmic disorders
EA200970948A1 (ru) * 2007-04-13 2010-08-30 Саузерн Рисерч Инститьют Антиангиогенные агенты и способы их применения
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
WO2014052836A2 (en) * 2012-09-27 2014-04-03 Dunman Paul M Methods and compositions for treating infection
WO2016154028A1 (en) * 2015-03-26 2016-09-29 Iversen Jacqueline M Methods and compositions to inhibit symptoms associated with veisalgia
DE102017130361A1 (de) 2017-12-18 2019-07-04 Lsp Innovative Automotive Systems Gmbh Statorzahn und Stator mit guter elektrischer Isolierung und gleichzeitig sehr hoher Wärmeleitfähigkeit zur Leistungssteigerung von Elektromotoren

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US4254129A (en) 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
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US4829064A (en) 1987-06-08 1989-05-09 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4996061A (en) 1987-10-07 1991-02-26 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol-decongestant combination
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CA2117892C (en) * 1992-04-10 2001-12-18 Chi-Hsin R. King 4-diphenylmethyl piperidine derivatives and process for their preparation
NZ251834A (en) 1992-05-11 1997-07-27 Merrell Dow Pharma Use of acid derivatives of terfenadine as antihistamines
DK1214937T3 (da) 1992-08-03 2007-09-17 Sepracor Inc Terfenadincarboxylat og behandling af hudirritation
ATE174589T1 (de) * 1993-06-24 1999-01-15 Albany Molecular Res Inc Verfahren zur herstellung von piperidinderivaten
HU226037B1 (en) * 1993-06-25 2008-03-28 Aventis Inc Process for producing antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives and novel intermediates
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WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate

Also Published As

Publication number Publication date
HUT71889A (en) 1996-02-28
PT1214937E (pt) 2007-07-25
DE69334008T2 (de) 2006-10-19
PL174373B1 (pl) 1998-07-31
AU1842999A (en) 1999-04-29
ES2284740T3 (es) 2007-11-16
DE69316660T2 (de) 1998-05-07
BR9306841A (pt) 1998-12-08
EP0815860A3 (en) 1998-01-14
EP0701443B2 (en) 2000-11-22
DE69316660D1 (de) 1998-02-26
AU675240B2 (en) 1997-01-30
ATE322899T1 (de) 2006-04-15
EP0701443B1 (en) 1998-01-21
EP1688142A1 (en) 2006-08-09
JP2000086514A (ja) 2000-03-28
GR3035417T3 (en) 2001-05-31
JP2000086515A (ja) 2000-03-28
AU4798693A (en) 1994-03-03
SK12495A3 (en) 1997-01-08
HK1045806B (zh) 2008-03-14
CA2141572A1 (en) 1994-02-17
ES2086270T3 (es) 1998-03-01
ES2257757T3 (es) 2006-08-01
GB9502183D0 (en) 1995-03-22
CZ27495A3 (en) 1996-09-11
NO950374D0 (no) 1995-02-01
DE9320925U1 (de) 1995-08-31
JP2000086512A (ja) 2000-03-28
DE69316660T3 (de) 2001-04-05
JPH08500348A (ja) 1996-01-16
EP1214937A2 (en) 2002-06-19
PL307339A1 (en) 1995-05-15
JP3041954B2 (ja) 2000-05-15
FI950467A (fi) 1995-03-31
GR3026530T3 (en) 1998-07-31
ATE363283T1 (de) 2007-06-15
NO950374L (no) 1995-03-29
JP2000086513A (ja) 2000-03-28
EP1214937B1 (en) 2007-05-30
HK1045806A1 (en) 2002-12-13
ATE162399T1 (de) 1998-02-15
HU9500313D0 (en) 1995-03-28
RU95107881A (ru) 1996-11-27
EP1214937A3 (en) 2002-10-30
GB2284351A (en) 1995-06-07
RU2167657C2 (ru) 2001-05-27
JP2000086516A (ja) 2000-03-28
KR950702420A (ko) 1995-07-29
JP3037697B2 (ja) 2000-04-24
JP3288662B2 (ja) 2002-06-04
ES2086270T5 (es) 2001-02-01
GB2284351B (en) 1996-11-27
DE69334145T2 (de) 2008-01-24
HU226242B1 (en) 2008-07-28
ES2086270T1 (es) 1996-07-01
RO116043B1 (ro) 2000-10-30
AU7182296A (en) 1997-01-30
EP0701443A1 (en) 1996-03-20
US5375693A (en) 1994-12-27
DE701443T1 (de) 1997-01-30
EP0815860B1 (en) 2006-04-12
WO1994003170A1 (en) 1994-02-17
PT815860E (pt) 2006-08-31
DE69334008D1 (de) 2006-05-24
JP3288661B2 (ja) 2002-06-04
GR960300024T1 (en) 1996-05-31
DK0815860T3 (da) 2006-08-14
NO310644B1 (no) 2001-08-06
CA2141572C (en) 2001-02-06
DE69334145D1 (de) 2007-07-12
DK0701443T3 (da) 1998-02-09
FI950467A0 (fi) 1995-02-02
DK0701443T4 (da) 2000-12-18
JP3288660B2 (ja) 2002-06-04
EP0815860A2 (en) 1998-01-07

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