NO310644B1 - Anvendelse av terfenadinmetabolitt og dens optisk rene isomerer for fremstilling av et farmasöytisk preparat forbehandling av allergisk rhinitt - Google Patents
Anvendelse av terfenadinmetabolitt og dens optisk rene isomerer for fremstilling av et farmasöytisk preparat forbehandling av allergisk rhinitt Download PDFInfo
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- NO310644B1 NO310644B1 NO19950374A NO950374A NO310644B1 NO 310644 B1 NO310644 B1 NO 310644B1 NO 19950374 A NO19950374 A NO 19950374A NO 950374 A NO950374 A NO 950374A NO 310644 B1 NO310644 B1 NO 310644B1
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- Prior art keywords
- terfenadine
- compound
- formula
- acid
- preparation
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92418292A | 1992-08-03 | 1992-08-03 | |
| US92415692A | 1992-08-03 | 1992-08-03 | |
| PCT/US1993/007260 WO1994003170A1 (en) | 1992-08-03 | 1993-08-03 | Terfenadine metabolites and their optically pure isomers for treating allergic disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO950374D0 NO950374D0 (no) | 1995-02-01 |
| NO950374L NO950374L (no) | 1995-03-29 |
| NO310644B1 true NO310644B1 (no) | 2001-08-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19950374A NO310644B1 (no) | 1992-08-03 | 1995-02-01 | Anvendelse av terfenadinmetabolitt og dens optisk rene isomerer for fremstilling av et farmasöytisk preparat forbehandling av allergisk rhinitt |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5375693A (da) |
| EP (4) | EP0815860B1 (da) |
| JP (6) | JP3041954B2 (da) |
| KR (1) | KR950702420A (da) |
| AT (3) | ATE363283T1 (da) |
| AU (3) | AU675240B2 (da) |
| BR (1) | BR9306841A (da) |
| CA (1) | CA2141572C (da) |
| CZ (1) | CZ27495A3 (da) |
| DE (5) | DE69316660T3 (da) |
| DK (3) | DK1214937T3 (da) |
| ES (3) | ES2257757T3 (da) |
| FI (1) | FI950467A (da) |
| GB (1) | GB2284351B (da) |
| GR (3) | GR960300024T1 (da) |
| HK (1) | HK1045806B (da) |
| HU (1) | HU226242B1 (da) |
| NO (1) | NO310644B1 (da) |
| PL (1) | PL174373B1 (da) |
| PT (2) | PT815860E (da) |
| RO (1) | RO116043B1 (da) |
| RU (1) | RU2167657C2 (da) |
| SK (1) | SK12495A3 (da) |
| WO (1) | WO1994003170A1 (da) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ251834A (en) * | 1992-05-11 | 1997-07-27 | Merrell Dow Pharma | Use of acid derivatives of terfenadine as antihistamines |
| DK1214937T3 (da) | 1992-08-03 | 2007-09-17 | Sepracor Inc | Terfenadincarboxylat og behandling af hudirritation |
| US20020007068A1 (en) | 1999-07-16 | 2002-01-17 | D'ambra Thomas E. | Piperidine derivatives and process for their production |
| ATE174589T1 (de) * | 1993-06-24 | 1999-01-15 | Albany Molecular Res Inc | Verfahren zur herstellung von piperidinderivaten |
| WO1995010278A1 (en) * | 1993-10-15 | 1995-04-20 | Hoechst Marion Roussel, Inc. | Treatment of allergic disorders with terfenadine carboxylate |
| US20030045722A1 (en) * | 1994-05-18 | 2003-03-06 | Henton Daniel R. | Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof |
| EP1178041A1 (en) | 1994-05-18 | 2002-02-06 | Aventis Pharmaceuticals Inc. | Process for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives |
| US5455049A (en) * | 1995-01-04 | 1995-10-03 | Ascent Pharmaceuticals, Inc. | Terfenadine oral powder |
| MX9706449A (es) * | 1995-02-28 | 1997-11-29 | Hoechst Marion Roussel Inc | Composicion farmaceutica para compuestos de piperidinalcanol. |
| GB9513972D0 (en) * | 1995-07-08 | 1995-09-06 | Merck Sharp & Dohme | Pharmaceutical compositions |
| US5906747A (en) * | 1995-11-13 | 1999-05-25 | Biosepra Inc. | Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates |
| US6355656B1 (en) | 1995-12-04 | 2002-03-12 | Celgene Corporation | Phenidate drug formulations having diminished abuse potential |
| US5908850A (en) * | 1995-12-04 | 1999-06-01 | Celgene Corporation | Method of treating attention deficit disorders with d-threo methylphenidate |
| US6486177B2 (en) * | 1995-12-04 | 2002-11-26 | Celgene Corporation | Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
| US5837284A (en) * | 1995-12-04 | 1998-11-17 | Mehta; Atul M. | Delivery of multiple doses of medications |
| US5922736A (en) * | 1995-12-04 | 1999-07-13 | Celegene Corporation | Chronic, bolus administration of D-threo methylphenidate |
| US5733756A (en) * | 1996-01-05 | 1998-03-31 | Celgene Corporation | Lactams and processes for stereoselective enrichment of lactams, amides, and esters |
| US6201124B1 (en) | 1995-12-21 | 2001-03-13 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| US6153754A (en) | 1995-12-21 | 2000-11-28 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| ES2124167B1 (es) * | 1996-06-04 | 1999-09-16 | Espanola Prod Quimicos | Nuevos derivados del bencimidazol con actividad antihistaminica. |
| US5925761A (en) * | 1997-02-04 | 1999-07-20 | Sepracor Inc. | Synthesis of terfenadine and derivatives |
| US6962997B1 (en) * | 1997-05-22 | 2005-11-08 | Celgene Corporation | Process and intermediates for resolving piperidyl acetamide steroisomers |
| ID22891A (id) * | 1997-08-26 | 1999-12-16 | Hoechst Marion Roussel Inc | Komposisi farmasi untuk kombinasi piperidinoalkanol-dekongestan |
| US6194431B1 (en) * | 1998-04-14 | 2001-02-27 | Paul D. Rubin | Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors |
| DE19913862C2 (de) * | 1999-03-26 | 2003-04-10 | Forschungszentrum Juelich Gmbh | Verfahren zur biokatalysierten Umsetzung schlecht wasserlöslicher Substanzen |
| DE10007203A1 (de) * | 2000-02-17 | 2001-08-23 | Asta Medica Ag | Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis |
| US6613907B2 (en) | 2000-11-08 | 2003-09-02 | Amr Technology, Inc. | Process for the production of piperidine derivatives with microorganisms |
| WO2002080857A2 (en) * | 2001-04-09 | 2002-10-17 | Teva Pharmaceutical Industries Ltd. | Polymorphs of fexofenadine hydrochloride |
| US20030021849A1 (en) * | 2001-04-09 | 2003-01-30 | Ben-Zion Dolitzky | Polymorphs of fexofenadine hydrochloride |
| WO2003020274A1 (en) * | 2001-08-30 | 2003-03-13 | Aventis Pharmaceuticals Inc. | Treatment of atopic dermatitis |
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1993
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