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DK1140935T3 - 1,2-anellerede quinolinderivater - Google Patents

1,2-anellerede quinolinderivater

Info

Publication number
DK1140935T3
DK1140935T3 DK99969220T DK99969220T DK1140935T3 DK 1140935 T3 DK1140935 T3 DK 1140935T3 DK 99969220 T DK99969220 T DK 99969220T DK 99969220 T DK99969220 T DK 99969220T DK 1140935 T3 DK1140935 T3 DK 1140935T3
Authority
DK
Denmark
Prior art keywords
celled
quinoline derivatives
quinoline
derivatives
celled quinoline
Prior art date
Application number
DK99969220T
Other languages
Danish (da)
English (en)
Inventor
Patrick Rene Angibaud
Marc Gaston Venet
Xavier Marc Bourdrez
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1140935T3 publication Critical patent/DK1140935T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
DK99969220T 1998-12-23 1999-12-17 1,2-anellerede quinolinderivater DK1140935T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98204444 1998-12-23
PCT/EP1999/010214 WO2000039082A2 (en) 1998-12-23 1999-12-17 1,2-annelated quinoline derivatives

Publications (1)

Publication Number Publication Date
DK1140935T3 true DK1140935T3 (da) 2003-09-01

Family

ID=8234557

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99969220T DK1140935T3 (da) 1998-12-23 1999-12-17 1,2-anellerede quinolinderivater

Country Status (32)

Country Link
US (2) US6458800B1 (xx)
EP (1) EP1140935B1 (xx)
JP (1) JP4725940B2 (xx)
KR (2) KR100712226B1 (xx)
CN (1) CN1178938C (xx)
AR (1) AR021995A1 (xx)
AT (1) ATE240327T1 (xx)
AU (1) AU765437B2 (xx)
BG (1) BG65124B1 (xx)
BR (1) BR9916827A (xx)
CA (1) CA2355717C (xx)
CZ (1) CZ302374B6 (xx)
DE (1) DE69907964T2 (xx)
DK (1) DK1140935T3 (xx)
EA (1) EA004542B1 (xx)
EE (1) EE04962B1 (xx)
ES (1) ES2200591T3 (xx)
HK (1) HK1038746B (xx)
HR (1) HRP20010454B1 (xx)
HU (1) HU229404B1 (xx)
ID (1) ID29241A (xx)
IL (2) IL143859A0 (xx)
NO (1) NO318922B1 (xx)
PL (1) PL199080B1 (xx)
PT (1) PT1140935E (xx)
SI (1) SI1140935T1 (xx)
SK (1) SK286072B6 (xx)
TR (1) TR200101961T2 (xx)
TW (1) TW531533B (xx)
UA (1) UA71592C2 (xx)
WO (1) WO2000039082A2 (xx)
ZA (1) ZA200105136B (xx)

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JP2003525246A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 白金化合物とのファルネシルタンパク質トランスフェラーゼ阻害剤の組み合わせ剤
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EP1390033A1 (en) * 2001-04-25 2004-02-25 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitors for treating cachexia
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JP2005519876A (ja) * 2001-11-27 2005-07-07 メルク　エンド　カムパニー　インコーポレーテッド ２−アミノキノリン化合物
JP4537710B2 (ja) 2001-12-19 2010-09-08 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ファルネシルトランスフェラーゼ阻害剤としての炭素連結トリアゾールで置換されている１，８−アネル化キノリン誘導体
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US20030125268A1 (en) * 2002-08-28 2003-07-03 Rybak Mary Ellen Margaret Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives
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Also Published As

Publication number Publication date
IL143859A0 (en) 2002-04-21
ID29241A (id) 2001-08-16
HUP0104582A3 (en) 2002-12-28
HU229404B1 (en) 2013-12-30
KR100712226B1 (ko) 2007-04-27
EA200100708A1 (ru) 2001-12-24
EE200100318A (et) 2002-10-15
EP1140935B1 (en) 2003-05-14
CN1178938C (zh) 2004-12-08
IL143859A (en) 2008-04-13
KR20010087396A (ko) 2001-09-15
EA004542B1 (ru) 2004-06-24
AU2795300A (en) 2000-07-31
US6914066B2 (en) 2005-07-05
TW531533B (en) 2003-05-11
SI1140935T1 (en) 2003-10-31
HUP0104582A2 (hu) 2002-04-29
AU765437B2 (en) 2003-09-18
AR021995A1 (es) 2002-09-04
EP1140935A2 (en) 2001-10-10
BR9916827A (pt) 2001-10-16
WO2000039082A2 (en) 2000-07-06
DE69907964D1 (de) 2003-06-18
CZ302374B6 (cs) 2011-04-20
JP2002533435A (ja) 2002-10-08
US6458800B1 (en) 2002-10-01
WO2000039082A3 (en) 2000-10-26
ES2200591T3 (es) 2004-03-01
NO20013088D0 (no) 2001-06-21
BG105631A (en) 2002-02-28
CZ20012142A3 (cs) 2002-01-16
NO318922B1 (no) 2005-05-23
ATE240327T1 (de) 2003-05-15
CA2355717C (en) 2011-02-08
BG65124B1 (bg) 2007-03-30
HK1038746A1 (en) 2002-03-28
UA71592C2 (uk) 2004-12-15
NO20013088L (no) 2001-06-21
JP4725940B2 (ja) 2011-07-13
SK286072B6 (sk) 2008-02-05
KR100818541B1 (ko) 2008-04-02
PL199080B1 (pl) 2008-08-29
HRP20010454A2 (en) 2002-06-30
TR200101961T2 (tr) 2001-12-21
ZA200105136B (en) 2002-06-21
SK8732001A3 (en) 2002-02-05
HK1038746B (zh) 2003-09-05
US20030119843A1 (en) 2003-06-26
DE69907964T2 (de) 2004-02-19
CN1331693A (zh) 2002-01-16
PL349504A1 (en) 2002-07-29
CA2355717A1 (en) 2000-07-06
HRP20010454B1 (en) 2004-06-30
KR20060117380A (ko) 2006-11-16
PT1140935E (pt) 2003-10-31
EE04962B1 (et) 2008-02-15

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