YU40321B - Process for obtaining pyrrolidine derivatives - Google Patents

Process for obtaining pyrrolidine derivatives

Info

Publication number: YU40321B
Authority: YU; Yugoslavia
Prior art keywords: pyrrolidine derivatives; obtaining; obtaining pyrrolidine; derivatives; pyrrolidine
Prior art date: 1977-02-11

Application number

YU302/78A

Other languages

English (en)

Other versions

YU30278A (en

Inventor

S Banfi

R Pellegata

G Pifferi

Original Assignee

Isf Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-02-11

Filing date

1978-02-09

Publication date

1985-12-31

1978-02-09 Application filed by Isf Spa filed Critical Isf Spa

1983-01-21 Publication of YU30278A publication Critical patent/YU30278A/xx

1985-12-31 Publication of YU40321B publication Critical patent/YU40321B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- B—PERFORMING OPERATIONS; TRANSPORTING
- B43—WRITING OR DRAWING IMPLEMENTS; BUREAU ACCESSORIES
- B43K—IMPLEMENTS FOR WRITING OR DRAWING
- B43K24/00—Mechanisms for selecting, projecting, retracting or locking writing units
- B43K24/02—Mechanisms for selecting, projecting, retracting or locking writing units for locking a single writing unit in only fully projected or retracted positions
- B43K24/08—Mechanisms for selecting, projecting, retracting or locking writing units for locking a single writing unit in only fully projected or retracted positions operated by push-buttons
- B43K24/084—Mechanisms for selecting, projecting, retracting or locking writing units for locking a single writing unit in only fully projected or retracted positions operated by push-buttons with saw-like or analogous cams
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J115/00—Adhesives based on rubber derivatives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

YU302/78A 1977-02-11 1978-02-09 Process for obtaining pyrrolidine derivatives YU40321B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT20227/77A IT1075280B (it)	1977-02-11	1977-02-11	Procedimento per la preparazione di derivati pirrolidinici

Publications (2)

Publication Number	Publication Date
YU30278A YU30278A (en)	1983-01-21
YU40321B true YU40321B (en)	1985-12-31

Family

ID=11164931

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU302/78A YU40321B (en)	1977-02-11	1978-02-09	Process for obtaining pyrrolidine derivatives

Country Status (26)

Country	Link
US (1)	US4173569A (xx)
JP (1)	JPS53101367A (xx)
AR (1)	AR223958A1 (xx)
AT (1)	AT362782B (xx)
AU (1)	AU513992B2 (xx)
BE (1)	BE863883A (xx)
CA (1)	CA1087200A (xx)
CH (1)	CH637928A5 (xx)
CS (1)	CS214800B2 (xx)
DE (2)	DE2758939A1 (xx)
DK (1)	DK155733C (xx)
ES (1)	ES466856A1 (xx)
FI (1)	FI67695C (xx)
FR (1)	FR2380257A1 (xx)
GB (1)	GB1588075A (xx)
HU (1)	HU178587B (xx)
IN (1)	IN148327B (xx)
IT (1)	IT1075280B (xx)
MX (1)	MX5950E (xx)
NL (1)	NL190412C (xx)
NO (1)	NO148148C (xx)
NZ (1)	NZ186431A (xx)
PL (1)	PL112858B1 (xx)
PT (1)	PT67642A (xx)
SU (1)	SU755195A3 (xx)
YU (1)	YU40321B (xx)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1141287B (it) *	1979-06-13	1986-10-01	Nattermann A & Cie	Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
FR2515179A1 (fr) *	1981-07-24	1983-04-29	Hoffmann La Roche	Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
IT1206699B (it) *	1984-02-27	1989-04-27	Isf Spa	Procedimento per preparare derivati di pirrolidone.
IT1173768B (it) *	1984-04-02	1987-06-24	Isf Spa	Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti
CH666483A5 (de) *	1985-01-16	1988-07-29	Lonza Ag	Verfahren zur herstellung von thiotetronsaeure.
DE3683728D1 (de) *	1985-07-26	1992-03-12	Denki Kagaku Kogyo Kk	Verfahren zur herstellung von oxiracetam.
IL80071A0 (en) *	1985-09-24	1986-12-31	Lonza Ag	Pyrrolidine acetamide derivatives
CH668423A5 (de) *	1986-06-19	1988-12-30	Lonza Ag	Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen.
HU195773B (en) *	1985-09-24	1988-07-28	Lonza Ag	Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid
CH666891A5 (de) *	1985-11-26	1988-08-31	Lonza Ag	4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung.
CH668424A5 (de) *	1986-06-26	1988-12-30	Lonza Ag	4-benzyloxy-3-pyrrolin-2-on-l-yl-acetamid, dessen herstellung und verwendung.
CH668422A5 (de) *	1986-06-26	1988-12-30	Lonza Ag	4-benzyloxy-3-pyrrolin-2-on, dessen herstellung und verwendung zur synthese von tetramsaeure.
CH667655A5 (de) *	1986-09-24	1988-10-31	Lonza Ag	Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen.
CH670644A5 (xx) *	1986-12-18	1989-06-30	Lonza Ag
IT1215581B (it) *	1987-06-25	1990-02-14	Roussel Maestretti Spa	Derivati della 1-benzil 2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro applicazione come prodotti medicinali.
DE3813416A1 (de) *	1988-04-21	1989-11-02	Hoechst Ag	3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte
ATE124396T1 (de) *	1988-09-06	1995-07-15	Lonza Ag	Verfahren zur herstellung von 5- alkyltetramsäuren.
FI95034C (fi) *	1989-03-15	1995-12-11	Lonza Ag	Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi
CH680293A5 (xx) *	1990-06-26	1992-07-31	Lonza Ag
GB9121289D0 (en) *	1991-10-08	1991-11-20	Isf Spa	Composition and use
JP2969616B2 (ja) *	1994-11-24	1999-11-02	田辺製薬株式会社	４−メルカプトピロリジン化合物の製法
US5679798A (en) *	1996-11-22	1997-10-21	Mona Industries, Inc.	Silicone monomers having a carboxyl functional group thereon
JP2001524071A (ja) *	1996-11-22	2001-11-27	モナ・インダストリーズ・インコーポレーテッド	カルボキシル官能基を有するシリコーンモノマー及びオリゴマー
KR100424393B1 (ko) *	2001-11-26	2004-03-24	한국화학연구원	옥시라세탐의 제조방법
JP4378326B2 (ja) *	2005-07-26	2009-12-02	キヤノン株式会社	駆動装置及び光量調節装置
EP2346500B1 (en)	2008-10-16	2017-05-17	The Johns Hopkins University	Methods and compositions for improving cognitive function
CN101747259B (zh) *	2008-12-18	2012-02-15	北京大学	氮杂糖类化合物及其合成方法及应用
CN101575309B (zh) *	2009-04-28	2011-05-18	中国医药集团总公司四川抗菌素工业研究所	合成(s)-奥拉西坦的方法
CN101704778B (zh) *	2009-09-30	2012-10-17	厦门市华兴化工有限公司	一种制备4-羟基吡咯烷酮-2-乙酰胺的方法
US10154988B2 (en)	2012-11-14	2018-12-18	The Johns Hopkins University	Methods and compositions for treating schizophrenia
DK2968220T3 (da)	2013-03-15	2021-06-14	Agenebio Inc	Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion
US10806717B2 (en)	2013-03-15	2020-10-20	The Johns Hopkins University	Methods and compositions for improving cognitive function
CN104513189B (zh) *	2014-12-19	2017-07-28	深圳市海滨制药有限公司	一种奥拉西坦中间体及其制备方法和应用
EP3299016B1 (en) *	2015-05-18	2020-12-16	Chongqing Runze Pharmaceutical Co. Ltd.	Use of dextrorotatory oxiracetam in pharmaceutical field
JP6899043B2 (ja)	2015-05-22	2021-07-07	エージンバイオ，インコーポレイテッド	レベチラセタムの持続放出性医薬組成物
EP3530650A4 (en) *	2016-10-24	2020-03-25	Chongqing Runze Pharmaceutical Company Limited	CRYSTALLINE FORM OF (R) -4-HYDROXY-2-OXO-1-PYRROLIDINE ACETAMIDE, PRODUCTION METHOD THEREFOR, AND USE THEREOF
US10696629B2 (en)	2016-10-24	2020-06-30	Chongqing Runze Pharmaceutical Company Limited	Crystalline form of dextral oxiracetam, preparation method therefor and use thereof
WO2018076783A1 (zh)	2016-10-24	2018-05-03	重庆润泽医药有限公司	右旋奥拉西坦晶型ii及其制备方法和用途
CN108299267A (zh)	2017-01-12	2018-07-20	重庆润泽医药有限公司	(r)-4-羟基-2-氧-1-吡咯烷乙酰胺的晶型及其制备方法和用途
CN114621128A (zh) *	2022-03-10	2022-06-14	成都百途医药科技有限公司	一种（s）-奥拉西坦的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR211398Q (es)	1975-08-13	1977-12-15	Isf Spa	Un procedimiento para preparar derivados de ( -pirrolin -2- on -1- il)-acilamida
IT1045043B (it)	1975-08-13	1980-04-21	Isf Spa	Derivati pirrolidinici

1977
- 1977-02-11 IT IT20227/77A patent/IT1075280B/it active Protection Beyond IP Right Term
- 1977-12-30 DE DE19772758939 patent/DE2758939A1/de not_active Withdrawn
- 1977-12-30 DE DE19772758937 patent/DE2758937A1/de active Granted
1978
- 1978-02-08 US US05/876,169 patent/US4173569A/en not_active Expired - Lifetime
- 1978-02-08 IN IN104/DEL/78A patent/IN148327B/en unknown
- 1978-02-08 FI FI780407A patent/FI67695C/fi not_active IP Right Cessation
- 1978-02-08 AU AU33091/78A patent/AU513992B2/en not_active Expired
- 1978-02-08 CS CS78816A patent/CS214800B2/cs unknown
- 1978-02-08 AT AT0088878A patent/AT362782B/de not_active IP Right Cessation
- 1978-02-08 GB GB5046/78A patent/GB1588075A/en not_active Expired
- 1978-02-08 AR AR271030A patent/AR223958A1/es active
- 1978-02-09 CA CA296,540A patent/CA1087200A/en not_active Expired
- 1978-02-09 YU YU302/78A patent/YU40321B/xx unknown
- 1978-02-09 NZ NZ186431A patent/NZ186431A/xx unknown
- 1978-02-09 NL NLAANVRAGE7801500,A patent/NL190412C/xx not_active IP Right Cessation
- 1978-02-09 MX MX786832U patent/MX5950E/es unknown
- 1978-02-09 CH CH145778A patent/CH637928A5/de not_active IP Right Cessation
- 1978-02-09 PT PT67642A patent/PT67642A/pt unknown
- 1978-02-09 HU HU78IE824A patent/HU178587B/hu not_active IP Right Cessation
- 1978-02-10 BE BE185100A patent/BE863883A/xx not_active IP Right Cessation
- 1978-02-10 PL PL1978204549A patent/PL112858B1/pl unknown
- 1978-02-10 JP JP1484478A patent/JPS53101367A/ja active Granted
- 1978-02-10 SU SU782577623A patent/SU755195A3/ru active
- 1978-02-10 NO NO780464A patent/NO148148C/no unknown
- 1978-02-10 DK DK063178A patent/DK155733C/da not_active IP Right Cessation
- 1978-02-10 ES ES466856A patent/ES466856A1/es not_active Expired
- 1978-02-13 FR FR7803961A patent/FR2380257A1/fr active Granted

Also Published As

Publication number	Publication date
MX5950E (es)	1984-09-06
GB1588075A (en)	1981-04-15
NL190412C (nl)	1994-02-16
DE2758937A1 (de)	1978-08-17
NL7801500A (nl)	1978-08-15
SU755195A3 (en)	1980-08-07
FI67695C (fi)	1985-05-10
DE2758939A1 (de)	1978-08-17
CH637928A5 (de)	1983-08-31
HU178587B (en)	1982-05-28
US4173569A (en)	1979-11-06
CA1087200A (en)	1980-10-07
IN148327B (xx)	1981-01-17
AU513992B2 (en)	1981-01-15
AR223958A1 (es)	1981-10-15
NL190412B (nl)	1993-09-16
DK155733B (da)	1989-05-08
AU3309178A (en)	1979-08-16
IT1075280B (it)	1985-04-22
ATA88878A (de)	1980-11-15
NO148148C (no)	1983-08-17
NZ186431A (en)	1979-08-31
FI780407A (fi)	1978-08-12
DK155733C (da)	1989-09-25
CS214800B2 (en)	1982-05-28
FI67695B (fi)	1985-01-31
BE863883A (fr)	1978-08-10
NO148148B (no)	1983-05-09
PL204549A1 (pl)	1979-03-12
YU30278A (en)	1983-01-21
DE2758937C2 (xx)	1988-07-07
ES466856A1 (es)	1978-10-01
JPS53101367A (en)	1978-09-04
FR2380257B1 (xx)	1981-11-20
AT362782B (de)	1981-06-10
PL112858B1 (en)	1980-11-29
DK63178A (da)	1978-08-12
JPS6338348B2 (xx)	1988-07-29
FR2380257A1 (fr)	1978-09-08
NO780464L (no)	1978-08-14
PT67642A (en)	1978-03-01

Publication	Publication Date	Title
YU40321B (en)	1985-12-31	Process for obtaining pyrrolidine derivatives
YU177578A (en)	1983-01-21	Process for obtaining imidazo-quinazoline derivatives
YU199478A (en)	1982-10-31	Process for preparing triphenylalkene derivatives
YU30378A (en)	1982-10-31	Process for obtaining pyrrolidine derivatives
YU40147B (en)	1985-08-31	Process for obtaining pyrrolidine derivatives
YU233478A (en)	1983-01-21	Process for producing new pyrrole derivatives
PT67698A (en)	1978-03-01	Process for preparing new pyrrolidine derivatives
YU40334B (en)	1985-12-31	Process for obtaining isoxazolyl-carbamide derivatives
YU250378A (en)	1983-04-30	Process for obtaining n-cyano-and n-alkinyl-2-(substitutedphenoxy)-butyramids
HU178012B (en)	1982-02-28	Process for preparing oxidazolo-pyrimidine derivatives
HU177722B (en)	1981-12-28	Process for preparing 14-amino-morfine derivatives
YU137578A (en)	1983-01-21	Process for obtaining mercaptoacyl-aminobenzoylglycine
PT67614A (en)	1978-03-01	Process for preparing oxadiazolopyrimidine derivatives
GB1537867A (en)	1979-01-04	Process for preparing 4-acylamino-piperidine derivatives
YU39417B (en)	1984-12-31	Process for obtaining auranophine
YU300377A (en)	1982-10-31	Process for obtaining 4-amino-epimeric oleandomycins
HU178247B (en)	1982-04-28	Process for preparing benzolsulphonyl-carbamide derivatives
YU197078A (en)	1982-10-31	Process for obtaining new 3-amino-17a-aza-d-homoandrostane derivatives
HU178804B (en)	1982-06-28	Process for preparing 1-hidroxy-aporphine derivatives
HU179711B (en)	1982-11-29	Process for preparing steroid-spiro-oxazolidinone derivatives
PT67635A (en)	1978-03-01	Process for preparing everninomicin derivatives
YU285578A (en)	1982-10-31	Process for obtaining 210hydroxy-20-methyl-pregnane derivatives
YU40674B (en)	1986-04-30	Process for obtaining di-n-propylacetonitrile
YU160978A (en)	1982-08-31	Process for obtaining tetrahydro-s-triazine-thione
YU40418B (en)	1985-12-31	Process for obtainining halo-oxazoline derivatives