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IT1206699B - Procedimento per preparare derivati di pirrolidone. - Google Patents

Procedimento per preparare derivati di pirrolidone.

Info

Publication number
IT1206699B
IT1206699B IT8419802A IT1980284A IT1206699B IT 1206699 B IT1206699 B IT 1206699B IT 8419802 A IT8419802 A IT 8419802A IT 1980284 A IT1980284 A IT 1980284A IT 1206699 B IT1206699 B IT 1206699B
Authority
IT
Italy
Prior art keywords
sup
alkyl
hydrogen
preparing
procedure
Prior art date
Application number
IT8419802A
Other languages
English (en)
Other versions
IT8419802A0 (it
Inventor
Ugo Pfeiffer
Mario Pinza
Original Assignee
Isf Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isf Spa filed Critical Isf Spa
Publication of IT8419802A0 publication Critical patent/IT8419802A0/it
Priority to IT8419802A priority Critical patent/IT1206699B/it
Priority to FI850505A priority patent/FI81339C/fi
Priority to CA000474316A priority patent/CA1241333A/en
Priority to ES540601A priority patent/ES8700656A1/es
Priority to KR1019850001130A priority patent/KR920002295B1/ko
Priority to ZA851401A priority patent/ZA851401B/xx
Priority to EP85301278A priority patent/EP0154490B1/en
Priority to AU39180/85A priority patent/AU584605B2/en
Priority to HU85705A priority patent/HU193399B/hu
Priority to DK86185A priority patent/DK86185A/da
Priority to NZ226168A priority patent/NZ226168A/xx
Priority to NO850778A priority patent/NO166712C/no
Priority to IL74448A priority patent/IL74448A/xx
Priority to NZ211226A priority patent/NZ211226A/xx
Priority to DE8585301278T priority patent/DE3564264D1/de
Priority to AT85301278T priority patent/ATE36319T1/de
Priority to GR850485A priority patent/GR850485B/el
Priority to PH31916A priority patent/PH22518A/en
Priority to JP60038625A priority patent/JPH0791266B2/ja
Priority to PT80021A priority patent/PT80021B/pt
Priority to IL84952A priority patent/IL84952A/xx
Priority to ES552957A priority patent/ES8800135A1/es
Priority to HU861280A priority patent/HU195957B/hu
Priority to IL84952A priority patent/IL84952A0/xx
Priority to CA000558327A priority patent/CA1256883A/en
Priority to US07/165,340 priority patent/US4797496A/en
Priority to AU30247/89A priority patent/AU612000B2/en
Application granted granted Critical
Publication of IT1206699B publication Critical patent/IT1206699B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT8419802A 1984-02-27 1984-02-27 Procedimento per preparare derivati di pirrolidone. IT1206699B (it)

Priority Applications (27)

Application Number Priority Date Filing Date Title
IT8419802A IT1206699B (it) 1984-02-27 1984-02-27 Procedimento per preparare derivati di pirrolidone.
FI850505A FI81339C (fi) 1984-02-27 1985-02-07 Foerfarande foer framstaellning av pyrrolidinoderivat, mellanprodukt och dess framstaellningsfoerfarande.
CA000474316A CA1241333A (en) 1984-02-27 1985-02-14 PREPARATION OF PYRROLIDONE DERIVATIVES
ES540601A ES8700656A1 (es) 1984-02-27 1985-02-21 Un procedimiento para preparar un derivado de pirrolidinona.
KR1019850001130A KR920002295B1 (ko) 1984-02-27 1985-02-22 프롤리디논 유도체의 제조방법
ZA851401A ZA851401B (en) 1984-02-27 1985-02-25 A process for the preparation of pyrrolidone derivatives
IL74448A IL74448A (en) 1984-02-27 1985-02-26 Process for the preparation of pyrrolidone derivatives and certain intermediates therefor
AU39180/85A AU584605B2 (en) 1984-02-27 1985-02-26 A process for the preparation of 2-oxo-1- pyrrolidineacetamide derivatives
HU85705A HU193399B (en) 1984-02-27 1985-02-26 Process for producing pyrrolidone derivatives
DK86185A DK86185A (da) 1984-02-27 1985-02-26 Fremgangsmaade til fremstilling af 2-oxo-1-pyrrolidinacetamid-derivater
NZ226168A NZ226168A (en) 1984-02-27 1985-02-26 Aminoacetamide derivatives as intermediates in the preparation of pyrrolidin-2-one derivatives
NO850778A NO166712C (no) 1984-02-27 1985-02-26 Fremgangsmaate ved fremstilling av pyrrolidonderivater.
EP85301278A EP0154490B1 (en) 1984-02-27 1985-02-26 Process for the preparation of pyrrolidone derivatives
NZ211226A NZ211226A (en) 1984-02-27 1985-02-26 The preparation of pyrrolidinone derivatives
DE8585301278T DE3564264D1 (en) 1984-02-27 1985-02-26 Process for the preparation of pyrrolidone derivatives
AT85301278T ATE36319T1 (de) 1984-02-27 1985-02-26 Verfahren zur herstellung von pyrrolidonderivaten.
GR850485A GR850485B (it) 1984-02-27 1985-02-26
PH31916A PH22518A (en) 1984-02-27 1985-02-27 A process for the preparation of pyrrolidone derivatives
JP60038625A JPH0791266B2 (ja) 1984-02-27 1985-02-27 ピロリドン誘導体の製造方法
PT80021A PT80021B (pt) 1984-02-27 1985-02-27 Processo de preparacao de derivados da pirrolidinona
IL84952A IL84952A (en) 1984-02-27 1985-11-26 Intermediates for preparing 2-oxo-pyrrolidineacetamide derivatives
ES552957A ES8800135A1 (es) 1984-02-27 1986-03-13 Un procedimiento para preparar derivados de esteres alquilicos del acido b-hidroxibutanoico
HU861280A HU195957B (en) 1984-02-27 1986-03-26 Process for preparing betq-hydroxy-butyric acid ester derivatives
IL84952A IL84952A0 (en) 1984-02-27 1987-12-28 Intermediates for pyrrolidone derivatives
CA000558327A CA1256883A (en) 1984-02-27 1988-02-05 Intermediates for preparing pyrrolidinone derivatives
US07/165,340 US4797496A (en) 1984-02-27 1988-03-08 Process for the preparation of pyrrolidone derivatives
AU30247/89A AU612000B2 (en) 1984-02-27 1989-02-23 A process for the preparation of pyrrolidone derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8419802A IT1206699B (it) 1984-02-27 1984-02-27 Procedimento per preparare derivati di pirrolidone.

Publications (2)

Publication Number Publication Date
IT8419802A0 IT8419802A0 (it) 1984-02-27
IT1206699B true IT1206699B (it) 1989-04-27

Family

ID=11161351

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8419802A IT1206699B (it) 1984-02-27 1984-02-27 Procedimento per preparare derivati di pirrolidone.

Country Status (20)

Country Link
US (1) US4797496A (it)
EP (1) EP0154490B1 (it)
JP (1) JPH0791266B2 (it)
KR (1) KR920002295B1 (it)
AT (1) ATE36319T1 (it)
AU (2) AU584605B2 (it)
CA (1) CA1241333A (it)
DE (1) DE3564264D1 (it)
DK (1) DK86185A (it)
ES (2) ES8700656A1 (it)
FI (1) FI81339C (it)
GR (1) GR850485B (it)
HU (2) HU193399B (it)
IL (1) IL74448A (it)
IT (1) IT1206699B (it)
NO (1) NO166712C (it)
NZ (1) NZ211226A (it)
PH (1) PH22518A (it)
PT (1) PT80021B (it)
ZA (1) ZA851401B (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0223328A1 (en) 1985-07-26 1987-05-27 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing oxiracetam

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH668423A5 (de) * 1986-06-19 1988-12-30 Lonza Ag Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen.
CH666891A5 (de) * 1985-11-26 1988-08-31 Lonza Ag 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung.
DE3602254A1 (de) * 1986-01-25 1987-07-30 Basf Ag Verfahren zur herstellung von oxiranylcarbonsaeureestern
CH680293A5 (it) * 1990-06-26 1992-07-31 Lonza Ag
KR100424393B1 (ko) * 2001-11-26 2004-03-24 한국화학연구원 옥시라세탐의 제조방법
CN101704778B (zh) * 2009-09-30 2012-10-17 厦门市华兴化工有限公司 一种制备4-羟基吡咯烷酮-2-乙酰胺的方法
CN102249977B (zh) * 2011-08-11 2013-06-12 重庆润泽医药有限公司 4-羟基-2-氧代-1-吡咯烷乙酰胺外消旋体晶型ⅰ及其制备方法
CN102432516B (zh) * 2011-12-14 2013-10-09 山东阿如拉药物研究开发有限公司 奥拉西坦的精制方法
CN110615744B (zh) * 2018-06-20 2023-01-06 上海朴颐化学科技有限公司 一种布瓦西坦中间体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI51098C (fi) * 1975-03-27 1976-10-11 Medipolar Oy Menetelmä terapeuttisesti arvokkaan 2-okso-1-pyrrolidinyyliasetamidin valmistamiseksi.
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
IT1075564B (it) * 1977-02-11 1985-04-22 Isf Spa Procedimento per la preparazione di derivati pirrolidinici
IT1075280B (it) * 1977-02-11 1985-04-22 Isf Spa Procedimento per la preparazione di derivati pirrolidinici
JPS5812272B2 (ja) * 1981-04-28 1983-03-07 電気化学工業株式会社 ４−ヒドロキシ−２−ピロリドンの製造法
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
IT1173768B (it) * 1984-04-02 1987-06-24 Isf Spa Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0223328A1 (en) 1985-07-26 1987-05-27 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing oxiracetam

Also Published As

Publication number Publication date
KR920002295B1 (ko) 1992-03-21
ATE36319T1 (de) 1988-08-15
ES552957A0 (es) 1987-10-16
NO166712B (no) 1991-05-21
ES8800135A1 (es) 1987-10-16
ES8700656A1 (es) 1986-10-16
EP0154490A2 (en) 1985-09-11
NO850778L (no) 1985-08-28
FI81339B (fi) 1990-06-29
IT8419802A0 (it) 1984-02-27
NO166712C (no) 1991-08-28
AU612000B2 (en) 1991-06-27
DK86185D0 (da) 1985-02-26
AU584605B2 (en) 1989-06-01
IL74448A (en) 1989-01-31
FI850505A0 (fi) 1985-02-07
AU3024789A (en) 1989-06-22
KR850006171A (ko) 1985-10-02
FI850505L (fi) 1985-08-28
ES540601A0 (es) 1986-10-16
CA1241333A (en) 1988-08-30
CA1256883C (it) 1989-07-04
HUT38614A (en) 1986-06-30
JPH0791266B2 (ja) 1995-10-04
DK86185A (da) 1985-08-28
EP0154490B1 (en) 1988-08-10
HUT41391A (en) 1987-04-28
IL74448A0 (en) 1985-05-31
JPS60208957A (ja) 1985-10-21
FI81339C (fi) 1990-10-10
US4797496A (en) 1989-01-10
GR850485B (it) 1985-06-26
DE3564264D1 (en) 1988-09-15
PT80021B (pt) 1987-06-17
HU195957B (en) 1988-08-29
EP0154490A3 (en) 1986-02-12
NZ211226A (en) 1990-06-26
PH22518A (en) 1988-09-12
HU193399B (en) 1987-10-28
AU3918085A (en) 1985-09-05
ZA851401B (en) 1985-11-27

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