PT628044E - Nucleosidos terapeuticos - Google Patents
Nucleosidos terapeuticosInfo
- Publication number
- PT628044E PT628044E PT93904248T PT93904248T PT628044E PT 628044 E PT628044 E PT 628044E PT 93904248 T PT93904248 T PT 93904248T PT 93904248 T PT93904248 T PT 93904248T PT 628044 E PT628044 E PT 628044E
- Authority
- PT
- Portugal
- Prior art keywords
- therapeutic nucleosides
- nucleosides
- therapeutic
- preparation
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929204015A GB9204015D0 (en) | 1992-02-25 | 1992-02-25 | Therapeutic nucleosides |
Publications (1)
Publication Number | Publication Date |
---|---|
PT628044E true PT628044E (pt) | 2003-12-31 |
Family
ID=10711016
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT93904248T PT628044E (pt) | 1992-02-25 | 1993-02-24 | Nucleosidos terapeuticos |
Country Status (14)
Country | Link |
---|---|
US (5) | US5641889A (pt) |
EP (1) | EP0628044B1 (pt) |
JP (1) | JP3172533B2 (pt) |
KR (1) | KR100282584B1 (pt) |
AT (1) | ATE245646T1 (pt) |
AU (2) | AU3571093A (pt) |
CA (1) | CA2130755C (pt) |
DE (1) | DE69333109T2 (pt) |
DK (1) | DK0628044T3 (pt) |
ES (1) | ES2203615T3 (pt) |
GB (1) | GB9204015D0 (pt) |
HK (1) | HK1003941A1 (pt) |
PT (1) | PT628044E (pt) |
WO (1) | WO1993017020A2 (pt) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5631370A (en) | 1988-01-20 | 1997-05-20 | Regents Of The University Of Minnesota | Optically-active isomers of dideoxycarbocyclic nucleosides |
CA2001401A1 (en) * | 1988-10-25 | 1990-04-25 | Claude Piantadosi | Quaternary amine containing ether or ester lipid derivatives and therapeutic compositions |
GB9204015D0 (en) | 1992-02-25 | 1992-04-08 | Wellcome Found | Therapeutic nucleosides |
CA2164717C (en) * | 1993-06-10 | 2009-10-20 | Louis S. Kucera | Method of combatting hepatitis b virus infection |
HUT73412A (en) * | 1993-06-21 | 1996-07-29 | Merrell Pharma Inc | Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines |
EP0630897A3 (en) * | 1993-06-25 | 1995-03-01 | Bristol Myers Squibb Co | 3-hydroxy-4-hydroxymethyl-2-methylene-cyclopentyl purines and pyrimidines. |
WO1995022330A1 (en) * | 1994-02-17 | 1995-08-24 | Commonwealth Scientific And Industrial Research Organisation | Antiviral agents |
US7135584B2 (en) | 1995-08-07 | 2006-11-14 | Wake Forest University | Lipid analogs for treating viral infections |
CA2197319C (en) * | 1994-08-29 | 2009-01-27 | Louis S. Kucera | Lipid analogs for treating viral infections |
DK0904348T3 (da) | 1996-05-30 | 2005-02-14 | Lonza Ag | Fremgangsmåde til fremstilling af aminoalkoholer og derivater deraf |
US5866702A (en) * | 1996-08-02 | 1999-02-02 | Cv Therapeutics, Incorporation | Purine inhibitors of cyclin dependent kinase 2 |
SK284810B6 (sk) * | 1997-05-13 | 2005-12-01 | Lonza Ag | Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purín-9-yl)-2-cyklopentén-1-metanolu |
SK284596B6 (sk) * | 1997-11-27 | 2005-07-01 | Lonza Ag | Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purin-9-yl)-2-cyklopentén-1-metanolu alebo jeho solí |
US6362225B1 (en) * | 1999-01-21 | 2002-03-26 | George Andreakos | Target therapies for treating common viral infections |
US6514979B1 (en) | 1999-03-03 | 2003-02-04 | University Of Maryland Biotechnology Institute | Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monophosphate dehydrogenese inhibitors and uses therefor |
YU25500A (sh) | 1999-05-11 | 2003-08-29 | Pfizer Products Inc. | Postupak za sintezu analoga nukleozida |
EP1210347B1 (en) * | 1999-09-10 | 2004-06-23 | Stichting REGA V.Z.W. | Carbocyclic nucleosides and process for obtaining such |
US7026469B2 (en) | 2000-10-19 | 2006-04-11 | Wake Forest University School Of Medicine | Compositions and methods of double-targeting virus infections and cancer cells |
US7038059B2 (en) | 2000-10-18 | 2006-05-02 | Kuraray Co., Ltd. | Process for preparation of 4-n-substituted amino-2-aza-1-oxabicyclo[3.3.0] oct-2-ene-6-carboxylic acid esters and process for preparation of their intermediates |
WO2003002565A1 (en) | 2001-06-27 | 2003-01-09 | Cyclacel Limited | 2,6,9-substituted purine derivatives and their use n the treatment of proliferative disorders |
GB0219052D0 (en) | 2002-08-15 | 2002-09-25 | Cyclacel Ltd | New puring derivatives |
CA2463719A1 (en) | 2003-04-05 | 2004-10-05 | F. Hoffmann-La Roche Ag | Nucleotide analogs with six membered rings |
GB0320738D0 (en) * | 2003-09-04 | 2003-10-08 | Glaxo Group Ltd | Novel process |
US7230002B2 (en) | 2004-02-03 | 2007-06-12 | Glenmark Pharmaceuticals Ltd. | Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof |
WO2005075426A1 (en) * | 2004-02-03 | 2005-08-18 | Glenmark Pharmaceuticals Ltd. | Novel dipeptidyl peptidase iv inhibitors; processes for their preparation and compositions thereof |
US7767686B2 (en) * | 2006-03-03 | 2010-08-03 | Covidien Ag | Method of using adenosine receptor blockers during tissue ablation |
US20070208042A1 (en) * | 2006-03-03 | 2007-09-06 | Sherwood Services Ag | Method of using vasoconstrictive agents during energy-based tissue therapy |
EP2540727B1 (en) * | 2007-08-02 | 2018-07-25 | Millennium Pharmaceuticals, Inc. | Sulfamoylating reagent |
AU2009282572B2 (en) | 2008-08-20 | 2014-09-11 | Merck Sharp & Dohme Corp. | Azo-substituted pyridine and pyrimidine derivatives and their use in treating viral infections |
WO2010022121A1 (en) * | 2008-08-20 | 2010-02-25 | Schering Corporation | Substituted pyridine and pyrimidine derivatives and their use in treating viral infections |
WO2010022125A1 (en) | 2008-08-20 | 2010-02-25 | Schering Corporation | Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections |
JP5619743B2 (ja) | 2008-08-20 | 2014-11-05 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | エテニル置換ピリジンおよびピリミジン誘導体およびウイルス感染の治療におけるそれらの使用 |
KR101830715B1 (ko) | 2010-01-27 | 2018-04-04 | 비이브 헬쓰케어 컴퍼니 | Hiv 감염을 치료하기 위한 약학적 조합물 |
WO2012139230A1 (en) | 2011-04-14 | 2012-10-18 | Phonak Ag | Hearing instrument |
GB201513601D0 (en) * | 2015-07-31 | 2015-09-16 | Univ Liverpool | Antiviral compounds |
CN106220515A (zh) * | 2016-08-12 | 2016-12-14 | 郸城巨鑫生物科技有限公司 | 一种(1r,4s)‑1‑氨基‑4‑羟甲基‑2‑环戊烯盐酸盐的合成方法 |
WO2018181102A1 (ja) * | 2017-03-29 | 2018-10-04 | ヤマサ醤油株式会社 | ヌクレオシド誘導体又はその塩、及びそれを含む医薬組成物 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60139653A (ja) * | 1983-12-27 | 1985-07-24 | Yoshitomi Pharmaceut Ind Ltd | シクロペンテン誘導体 |
US4543255A (en) * | 1984-05-10 | 1985-09-24 | Southern Research Institute | Carbocyclic analogs of purine 2'-deoxyribofuranosides |
EP0219838A3 (en) * | 1985-10-22 | 1988-04-06 | Takeda Chemical Industries, Ltd. | Carbocyclic purine nucleosides, their production and use |
IN164556B (pt) * | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
US4734194A (en) * | 1986-03-25 | 1988-03-29 | The Upjohn Company | Combined filter and valve mechanism |
IN166499B (pt) * | 1987-02-12 | 1990-05-19 | Takeda Chemical Industries Ltd | |
GB8815265D0 (en) * | 1988-06-27 | 1988-08-03 | Wellcome Found | Therapeutic nucleosides |
KR910700054A (ko) * | 1988-12-12 | 1991-03-13 | 엠. 팔레스 피터 | B형 간염 비루스 감염의 예방 및 치료를 위한 방법 및 조성물 |
ES2067693T3 (es) * | 1989-10-16 | 1995-04-01 | Chiroscience Ltd | Azabicicloheptanona quiral y un procedimiento para su preparacion. |
MY104575A (en) * | 1989-12-22 | 1994-04-30 | The Wellcome Foundation Ltd | Therapeutic nucleosides. |
WO1991013549A1 (en) * | 1990-03-06 | 1991-09-19 | Virachem, Inc. | Methods and compositions for the prophylaxis and treatment of cytomegalovirus infections |
GB9204015D0 (en) | 1992-02-25 | 1992-04-08 | Wellcome Found | Therapeutic nucleosides |
-
1992
- 1992-02-25 GB GB929204015A patent/GB9204015D0/en active Pending
-
1993
- 1993-02-24 JP JP51465893A patent/JP3172533B2/ja not_active Expired - Lifetime
- 1993-02-24 ES ES93904248T patent/ES2203615T3/es not_active Expired - Lifetime
- 1993-02-24 WO PCT/GB1993/000378 patent/WO1993017020A2/en active IP Right Grant
- 1993-02-24 AT AT93904248T patent/ATE245646T1/de active
- 1993-02-24 US US08/295,656 patent/US5641889A/en not_active Expired - Lifetime
- 1993-02-24 DE DE69333109T patent/DE69333109T2/de not_active Expired - Lifetime
- 1993-02-24 CA CA002130755A patent/CA2130755C/en not_active Expired - Lifetime
- 1993-02-24 KR KR1019940702965A patent/KR100282584B1/ko not_active IP Right Cessation
- 1993-02-24 PT PT93904248T patent/PT628044E/pt unknown
- 1993-02-24 AU AU35710/93A patent/AU3571093A/en not_active Abandoned
- 1993-02-24 DK DK93904248T patent/DK0628044T3/da active
- 1993-02-24 EP EP93904248A patent/EP0628044B1/en not_active Expired - Lifetime
-
1996
- 1996-11-06 US US08/743,694 patent/US5840990A/en not_active Expired - Lifetime
-
1997
- 1997-06-13 AU AU24891/97A patent/AU707075B2/en not_active Expired
- 1997-11-07 US US08/965,987 patent/US5808147A/en not_active Expired - Lifetime
- 1997-11-07 US US08/965,986 patent/US5919941A/en not_active Expired - Lifetime
-
1998
- 1998-04-17 HK HK98103255A patent/HK1003941A1/xx not_active IP Right Cessation
- 1998-07-10 US US09/113,793 patent/US6392085B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
HK1003941A1 (en) | 1998-11-13 |
EP0628044A1 (en) | 1994-12-14 |
AU707075B2 (en) | 1999-07-01 |
AU2489197A (en) | 1997-08-28 |
JPH07504185A (ja) | 1995-05-11 |
US5840990A (en) | 1998-11-24 |
GB9204015D0 (en) | 1992-04-08 |
JP3172533B2 (ja) | 2001-06-04 |
ATE245646T1 (de) | 2003-08-15 |
US20010008946A1 (en) | 2001-07-19 |
ES2203615T3 (es) | 2004-04-16 |
US5919941A (en) | 1999-07-06 |
WO1993017020A2 (en) | 1993-09-02 |
US6392085B2 (en) | 2002-05-21 |
DK0628044T3 (da) | 2003-11-17 |
DE69333109D1 (de) | 2003-08-28 |
WO1993017020A3 (en) | 1994-03-17 |
DE69333109T2 (de) | 2004-04-15 |
KR100282584B1 (ko) | 2001-02-15 |
CA2130755A1 (en) | 1993-08-26 |
KR950700298A (ko) | 1995-01-16 |
EP0628044B1 (en) | 2003-07-23 |
US5641889A (en) | 1997-06-24 |
AU3571093A (en) | 1993-09-13 |
CA2130755C (en) | 2004-03-30 |
US5808147A (en) | 1998-09-15 |
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