PL2321356T3 - Przeciwciała monoklonalne przeciwko inhibitorowi szlaku czynnika tkankowego (TFPI) - Google Patents

Przeciwciała monoklonalne przeciwko inhibitorowi szlaku czynnika tkankowego (TFPI)

Info

Publication number: PL2321356T3
Authority: PL; Poland
Prior art keywords: tfpi; monoclonal antibodies; antibodies against; tissue factor; pathway inhibitor
Prior art date: 2008-08-04

Application number

PL09805438T

Other languages

English (en)

Inventor

Zhuozhi Wang

John E. Murphy

Junliang Pan

Haiyan Jiang

Bing Liu

Original Assignee

Bayer Healthcare Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-08-04

Filing date

2009-08-04

Publication date

2018-10-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41664165&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2321356(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-08-04 Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc

2018-10-31 Publication of PL2321356T3 publication Critical patent/PL2321356T3/pl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Mycology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Gastroenterology & Hepatology (AREA)
Tropical Medicine & Parasitology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL09805438T 2008-08-04 2009-08-04 Przeciwciała monoklonalne przeciwko inhibitorowi szlaku czynnika tkankowego (TFPI) PL2321356T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US8598008P	2008-08-04	2008-08-04
EP09805438.0A EP2321356B1 (en)	2008-08-04	2009-08-04	Monoclonal antibodies against tissue factor pathway inhibitor (tfpi)
PCT/US2009/052702 WO2010017196A2 (en)	2008-08-04	2009-08-04	Monoclonal antibodies against tissue factor pathway inhibitor (tfpi)

Publications (1)

Publication Number	Publication Date
PL2321356T3 true PL2321356T3 (pl)	2018-10-31

Family

ID=41664165

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL09805438T PL2321356T3 (pl)	2008-08-04	2009-08-04	Przeciwciała monoklonalne przeciwko inhibitorowi szlaku czynnika tkankowego (TFPI)

Country Status (35)

Country	Link
US (3)	US20120269817A1 (pl)
EP (1)	EP2321356B1 (pl)
JP (1)	JP5801194B2 (pl)
KR (5)	KR20180029106A (pl)
CN (4)	CN110437335A (pl)
AU (3)	AU2009279804C1 (pl)
BR (2)	BRPI0917418A2 (pl)
CA (4)	CA3138035A1 (pl)
CL (3)	CL2011000230A1 (pl)
CO (1)	CO6351803A2 (pl)
CR (1)	CR20110066A (pl)
CU (2)	CU23880B1 (pl)
CY (1)	CY1120670T1 (pl)
DK (1)	DK2321356T3 (pl)
DO (2)	DOP2011000045A (pl)
EC (1)	ECSP11010810A (pl)
ES (1)	ES2677329T3 (pl)
HR (1)	HRP20181095T1 (pl)
HU (1)	HUE038648T2 (pl)
IL (4)	IL210987A (pl)
LT (1)	LT2321356T (pl)
MX (1)	MX2011001351A (pl)
MY (1)	MY161844A (pl)
NZ (2)	NZ731392A (pl)
PE (2)	PE20110771A1 (pl)
PH (1)	PH12017502286A1 (pl)
PL (1)	PL2321356T3 (pl)
PT (1)	PT2321356T (pl)
SG (1)	SG10201703066PA (pl)
SI (1)	SI2321356T1 (pl)
SV (1)	SV2011003828A (pl)
TR (1)	TR201807252T4 (pl)
UA (2)	UA112050C2 (pl)
WO (1)	WO2010017196A2 (pl)
ZA (1)	ZA201100888B (pl)

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EA034214B1 (ru) *	2011-04-01	2020-01-17	Байер Хелфкеа Ллк	Выделенное моноклональное антитело или его антигенсвязывающий фрагмент, который связывается с эпитопом ингибитора пути тканевого фактора человека, содержащая его фармацевтическая композиция, способ применения этой композиции и кодирующая антитело молекула нуклеиновой кислоты
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ES2905085T3 (es) *	2014-09-17	2022-04-07	Novo Nordisk As	Anticuerpos que pueden unirse a dos epítopos en el inhibidor de la vía del factor tisular (1-161)
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KR102068915B1 (ko) *	2015-08-19	2020-01-22	화이자 인코포레이티드	조직 인자 경로 억제제 항체 및 그의 용도
JP6419664B2 (ja) *	2015-08-26	2018-11-07	バイエル・ヘルスケア・エルエルシーＢａｙｅｒＨｅａｌｔｈＣａｒｅＬＬＣ	組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
JP6559188B2 (ja) *	2017-07-06	2019-08-14	バイエル・ヘルスケア・エルエルシーＢａｙｅｒＨｅａｌｔｈＣａｒｅＬＬＣ	組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
JP2018038398A (ja) *	2017-09-04	2018-03-15	バイエル・ヘルスケア・エルエルシーＢａｙｅｒＨｅａｌｔｈＣａｒｅＬＬＣ	組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
JP2018108089A (ja) *	2018-02-19	2018-07-12	バイエル・ヘルスケア・エルエルシーＢａｙｅｒＨｅａｌｔｈＣａｒｅＬＬＣ	組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
CN109053882B (zh) *	2018-08-28	2019-08-23	东莞市朋志生物科技有限公司	一种ns1蛋白的结合蛋白以及应用
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JP6848016B2 (ja) *	2019-07-16	2021-03-24	バイエル・ヘルスケア・エルエルシーＢａｙｅｒＨｅａｌｔｈＣａｒｅＬＬＣ	組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
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Publication number	Publication date
IL277162B (en)	2021-05-31
US20170342162A1 (en)	2017-11-30
CU20110031A7 (es)	2012-06-21
BR122017025538A2 (pt)	2021-01-19
NZ714313A (en)	2017-05-26
AU2016201230A1 (en)	2016-03-17
UA120596C2 (uk)	2020-01-10
CN110437335A (zh)	2019-11-12
DOP2011000045A (es)	2011-10-31
KR101769725B1 (ko)	2017-08-18
PE20110771A1 (es)	2011-10-14
ECSP11010810A (es)	2011-03-31
KR20190099341A (ko)	2019-08-26
CA3081514A1 (en)	2010-02-11
CA2733075A1 (en)	2010-02-11
CA2733075C (en)	2018-10-23
CL2016003015A1 (es)	2017-06-30
CU23900B1 (es)	2013-03-28
CN102143979B (zh)	2016-08-03
EP2321356A2 (en)	2011-05-18
KR101692085B1 (ko)	2017-01-03
MX2011001351A (es)	2011-10-12
AU2018203753A1 (en)	2018-06-21
CY1120670T1 (el)	2019-12-11
IL250640B (en)	2020-10-29
CO6351803A2 (es)	2011-12-20
CU23880B1 (es)	2013-04-19
ES2677329T3 (es)	2018-08-01
MY161844A (en)	2017-05-15
DK2321356T3 (en)	2018-07-23
IL210987A (en)	2017-03-30
KR20110043736A (ko)	2011-04-27
CL2016003014A1 (es)	2017-06-30
TR201807252T4 (tr)	2018-06-21
UA112050C2 (uk)	2016-07-25
CN105944100A (zh)	2016-09-21
BRPI0917418A2 (pt)	2021-01-05
NZ731392A (en)	2018-10-26
CA2933259A1 (en)	2010-02-11
CR20110066A (es)	2011-05-25
US20180334509A1 (en)	2018-11-22
EP2321356A4 (en)	2013-02-13
HRP20181095T1 (hr)	2018-09-21
WO2010017196A2 (en)	2010-02-11
EP2321356B1 (en)	2018-04-11
PH12017502286A1 (en)	2019-11-11
KR20170005516A (ko)	2017-01-13
CU20110236A7 (es)	2012-07-31
US20120269817A1 (en)	2012-10-25
PE20141563A1 (es)	2014-10-24
IL282658A (en)	2021-06-30
AU2009279804C1 (en)	2017-01-19
LT2321356T (lt)	2018-09-10
WO2010017196A3 (en)	2010-11-04
SV2011003828A (es)	2011-05-20
JP2013500701A (ja)	2013-01-10
CN110452299A (zh)	2019-11-15
IL250640A0 (en)	2017-04-30
SG10201703066PA (en)	2017-05-30
JP5801194B2 (ja)	2015-10-28
SI2321356T1 (sl)	2018-09-28
IL210987A0 (en)	2011-04-28
CA3081514C (en)	2021-12-14
CN102143979A (zh)	2011-08-03
CN105944100B (zh)	2019-09-17
ZA201100888B (en)	2012-04-25
AU2009279804B2 (en)	2016-03-24
HUE038648T2 (hu)	2018-11-28
CA3138035A1 (en)	2010-02-11
CL2011000230A1 (es)	2011-06-24
AU2009279804A1 (en)	2010-02-11
KR20160091439A (ko)	2016-08-02
KR20180029106A (ko)	2018-03-19
PT2321356T (pt)	2018-07-17
CA2933259C (en)	2021-07-06
DOP2019000287A (es)	2019-12-15
IL277162A (en)	2020-10-29

Publication	Publication Date	Title
IL282658A (en)	2021-06-30	Monoclonal antibodies against tissue factor pathway inhibitor (TFPI)
IL277391A (en)	2020-11-30	Monoclonal antibodies are effective against tissue factor pathway inhibitor (TFPI)
IL283829A (en)	2021-07-29	Monoclonal antibodies against tissue factor pathway inhibitor (tfpi)
ZA201104599B (en)	2012-03-28	Antibodies against tissue factor pathway inhibitor