ID27414A - Penghambat-penghambat non-peptidil dari pengikat sel tergantung vla-4 yang bermanfaat dalam pengobatan penyakit-penyakit inflamasi, autoimun dan pernafasan - Google Patents
Penghambat-penghambat non-peptidil dari pengikat sel tergantung vla-4 yang bermanfaat dalam pengobatan penyakit-penyakit inflamasi, autoimun dan pernafasanInfo
- Publication number
- ID27414A ID27414A IDW20002723A ID20002723A ID27414A ID 27414 A ID27414 A ID 27414A ID W20002723 A IDW20002723 A ID W20002723A ID 20002723 A ID20002723 A ID 20002723A ID 27414 A ID27414 A ID 27414A
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- ID
- Indonesia
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- autoimun
- peptidil
- inflamation
- vla
- obstacles
- Prior art date
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- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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US9118098P | 1998-06-30 | 1998-06-30 |
Publications (1)
Publication Number | Publication Date |
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ID27414A true ID27414A (id) | 2001-04-05 |
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ID=22226483
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Application Number | Title | Priority Date | Filing Date |
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IDW20002723A ID27414A (id) | 1998-06-30 | 1999-05-31 | Penghambat-penghambat non-peptidil dari pengikat sel tergantung vla-4 yang bermanfaat dalam pengobatan penyakit-penyakit inflamasi, autoimun dan pernafasan |
Country Status (37)
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US (2) | US6355662B1 (pt) |
EP (1) | EP1091943B1 (pt) |
JP (1) | JP3676677B2 (pt) |
KR (1) | KR20010083081A (pt) |
CN (1) | CN1308616A (pt) |
AP (1) | AP1236A (pt) |
AR (1) | AR015312A1 (pt) |
AT (1) | ATE311371T1 (pt) |
AU (1) | AU758939B2 (pt) |
BG (1) | BG105190A (pt) |
BR (1) | BR9911701A (pt) |
CA (1) | CA2336625A1 (pt) |
CO (1) | CO5320599A1 (pt) |
CZ (1) | CZ20004909A3 (pt) |
DE (1) | DE69928667T2 (pt) |
EA (1) | EA004792B1 (pt) |
GT (1) | GT199900101A (pt) |
HN (1) | HN1999000099A (pt) |
HR (1) | HRP20000917A2 (pt) |
HU (1) | HUP0102477A3 (pt) |
ID (1) | ID27414A (pt) |
IL (1) | IL139584A0 (pt) |
IS (1) | IS5720A (pt) |
MA (1) | MA26640A1 (pt) |
NO (1) | NO20006600L (pt) |
NZ (1) | NZ508033A (pt) |
OA (1) | OA11577A (pt) |
PA (1) | PA8477001A1 (pt) |
PE (1) | PE20000762A1 (pt) |
PL (1) | PL345308A1 (pt) |
SK (1) | SK20052000A3 (pt) |
TN (1) | TNSN99110A1 (pt) |
TR (1) | TR200003848T2 (pt) |
UA (1) | UA66864C2 (pt) |
WO (1) | WO2000000477A1 (pt) |
YU (1) | YU77600A (pt) |
ZA (1) | ZA993777B (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6992107B1 (en) | 1995-03-10 | 2006-01-31 | Photocure Asa | Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy |
AU746963B2 (en) | 1998-06-12 | 2002-05-09 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Imidazolyl derivatives |
KR20010083081A (ko) * | 1998-06-30 | 2001-08-31 | 실버스타인 아써 에이. | 염증성질환, 자가면역질환 및 호흡기질환을 치료하는데유용한 브이엘에이-4-의존성 세포 결합의 비-펩티딜 억제제 |
US6518292B1 (en) * | 1999-03-12 | 2003-02-11 | Bristol-Myers Squibb Co. | Heterocyclic aromatic compounds usefuls as growth hormone secretagogues |
TWI283240B (en) * | 1999-06-30 | 2007-07-01 | Daiichi Seiyaku Co | VLA-4 inhibitor compounds |
US6756378B2 (en) * | 1999-06-30 | 2004-06-29 | Pharmacopeia Drug Discovery, Inc. | VLA-4 inhibitor compounds |
YU41202A (sh) | 1999-12-28 | 2005-03-15 | Pfizer Products Inc. | Ne-peptidni inhibitori vezivanja za ćeliju zavisnog od vla-4 korisni pri tretiranju inflamatornih, autoimunih i respiratornih bolesti |
WO2001056994A1 (en) * | 2000-02-04 | 2001-08-09 | Biogen, Inc. | Integrin antagonists |
US6638950B2 (en) | 2000-06-21 | 2003-10-28 | Bristol-Myers Squibb Pharma Company | Piperidine amides as modulators of chemokine receptor activity |
KR20030020960A (ko) * | 2000-08-01 | 2003-03-10 | 소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스. | 이미다졸일 유도체 |
GB2367816A (en) | 2000-10-09 | 2002-04-17 | Bayer Ag | Urea- and thiourea-containing derivatives of beta-amino acids |
TWI312779B (pt) | 2000-12-28 | 2009-08-01 | Daiichi Seiyaku Co | |
DE10111877A1 (de) * | 2001-03-10 | 2002-09-12 | Aventis Pharma Gmbh | Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
US20030013846A1 (en) * | 2001-05-03 | 2003-01-16 | Bing Wang | Pyruvate derivatives |
DK1392306T3 (da) * | 2001-06-06 | 2008-05-19 | Aventis Pharma Ltd | Substituerede tetrahydroisoquinoliner til anvendelse i behandlingen af inflammatoriske sygdomme |
GB2377933A (en) | 2001-07-06 | 2003-01-29 | Bayer Ag | Succinic acid derivatives useful as integrin antagonists |
DE10137595A1 (de) | 2001-08-01 | 2003-02-13 | Aventis Pharma Gmbh | Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung |
AU2002326948A1 (en) * | 2001-09-18 | 2003-04-01 | Bristol-Myers Squibb Company | Piperizinones as modulators of chemokine receptor activity |
EP1549640A4 (en) | 2002-06-17 | 2008-08-06 | Merck & Co Inc | 1 - ((5-ARYL-1,2,4-OXADIAZOL-3-YL) BENZYL) AZETIDINE-3-CARBOXYLATE AND 1 - ((5-ARYL-1,2,4-OXADIAZOL-3-YL) BENZYL) PYRROLIDIN-3-CARBOXYLATE AS EDG RECEPTOR AGONISTS |
PL374860A1 (en) * | 2002-07-09 | 2005-11-14 | Bristol-Myers Squibb Company | Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method |
CA2528586A1 (en) | 2003-07-24 | 2005-02-03 | Daiichi Pharmaceutical Co., Ltd. | Cyclohexanecarboxylic acid compound |
GB0402812D0 (en) * | 2004-02-09 | 2004-03-10 | Tanabe Seiyaku Co | Novel compounds |
US7309709B2 (en) * | 2004-04-01 | 2007-12-18 | Pfizer Inc. | Thiazole sulfonamide compounds for the treatment of neurodegenerative disorders |
TW200610754A (en) * | 2004-06-14 | 2006-04-01 | Daiichi Seiyaku Co | Vla-4 inhibitor |
US7453002B2 (en) | 2004-06-15 | 2008-11-18 | Bristol-Myers Squibb Company | Five-membered heterocycles useful as serine protease inhibitors |
EP1961750B1 (en) | 2005-12-13 | 2013-09-18 | Daiichi Sankyo Company, Limited | Vla-4 inhibitory drug |
US20120258093A1 (en) | 2009-08-20 | 2012-10-11 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Vla-4 as a biomarker for prognosis and target for therapy in duchenne muscular dystrophy |
US11168083B2 (en) | 2017-08-04 | 2021-11-09 | Takeda Pharmaceutical Company Limited | Inhibitors of Plasma Kallikrein and uses thereof |
US20240301512A1 (en) | 2021-01-29 | 2024-09-12 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of assessing the risk of developing progressive multifocal leukoencephalopathy in patients treated with vla-4 antagonists |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU646966B2 (en) * | 1991-08-23 | 1994-03-10 | Takeda Chemical Industries Ltd. | 2-piperazinone compounds, their production and use |
US6306840B1 (en) * | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
KR20010083081A (ko) * | 1998-06-30 | 2001-08-31 | 실버스타인 아써 에이. | 염증성질환, 자가면역질환 및 호흡기질환을 치료하는데유용한 브이엘에이-4-의존성 세포 결합의 비-펩티딜 억제제 |
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1999
- 1999-05-31 KR KR1020007015120A patent/KR20010083081A/ko active IP Right Grant
- 1999-05-31 TR TR2000/03848T patent/TR200003848T2/xx unknown
- 1999-05-31 PL PL99345308A patent/PL345308A1/xx not_active Application Discontinuation
- 1999-05-31 AT AT99921046T patent/ATE311371T1/de not_active IP Right Cessation
- 1999-05-31 BR BR9911701-0A patent/BR9911701A/pt not_active IP Right Cessation
- 1999-05-31 CN CN99808134A patent/CN1308616A/zh active Pending
- 1999-05-31 US US09/403,846 patent/US6355662B1/en not_active Expired - Fee Related
- 1999-05-31 HU HU0102477A patent/HUP0102477A3/hu unknown
- 1999-05-31 OA OA1200000361A patent/OA11577A/en unknown
- 1999-05-31 EA EA200001238A patent/EA004792B1/ru not_active IP Right Cessation
- 1999-05-31 UA UA2000127651A patent/UA66864C2/uk unknown
- 1999-05-31 WO PCT/IB1999/000973 patent/WO2000000477A1/en not_active Application Discontinuation
- 1999-05-31 CZ CZ20004909A patent/CZ20004909A3/cs unknown
- 1999-05-31 SK SK2005-2000A patent/SK20052000A3/sk unknown
- 1999-05-31 CA CA002336625A patent/CA2336625A1/en not_active Abandoned
- 1999-05-31 IL IL13958499A patent/IL139584A0/xx unknown
- 1999-05-31 DE DE69928667T patent/DE69928667T2/de not_active Expired - Fee Related
- 1999-05-31 JP JP2000557238A patent/JP3676677B2/ja not_active Expired - Fee Related
- 1999-05-31 YU YU77600A patent/YU77600A/sh unknown
- 1999-05-31 ID IDW20002723A patent/ID27414A/id unknown
- 1999-05-31 AU AU38416/99A patent/AU758939B2/en not_active Ceased
- 1999-05-31 EP EP99921046A patent/EP1091943B1/en not_active Expired - Lifetime
- 1999-05-31 NZ NZ508033A patent/NZ508033A/xx unknown
- 1999-06-03 AP APAP/P/1999/001561A patent/AP1236A/en active
- 1999-06-04 ZA ZA9903777A patent/ZA993777B/xx unknown
- 1999-06-07 MA MA25611A patent/MA26640A1/fr unknown
- 1999-06-09 TN TNTNSN99110A patent/TNSN99110A1/fr unknown
- 1999-06-16 AR ARP990102883A patent/AR015312A1/es not_active Application Discontinuation
- 1999-06-17 HN HN1999000099A patent/HN1999000099A/es unknown
- 1999-06-23 US US09/338,832 patent/US6306887B1/en not_active Expired - Fee Related
- 1999-06-25 GT GT199900101A patent/GT199900101A/es unknown
- 1999-06-25 PE PE1999000583A patent/PE20000762A1/es not_active Application Discontinuation
- 1999-06-29 PA PA19998477001A patent/PA8477001A1/es unknown
- 1999-06-30 CO CO99040934A patent/CO5320599A1/es not_active Application Discontinuation
-
2000
- 2000-11-21 IS IS5720A patent/IS5720A/is unknown
- 2000-12-22 NO NO20006600A patent/NO20006600L/no not_active Application Discontinuation
- 2000-12-29 HR HR20000917A patent/HRP20000917A2/hr not_active Application Discontinuation
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2001
- 2001-01-26 BG BG105190A patent/BG105190A/xx unknown
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