EP2933334B1
(en)
|
2003-02-18 |
2019-09-18 |
Baylor College of Medicine |
Induced activation in dendritic cells
|
US7435596B2
(en)
|
2004-11-04 |
2008-10-14 |
St. Jude Children's Research Hospital, Inc. |
Modified cell line and method for expansion of NK cell
|
US20130266551A1
(en)
|
2003-11-05 |
2013-10-10 |
St. Jude Children's Research Hospital, Inc. |
Chimeric receptors with 4-1bb stimulatory signaling domain
|
US8129184B2
(en)
|
2006-09-26 |
2012-03-06 |
Cedars-Sinai Medical Center |
Cancer stem cell antigen vaccines and methods
|
US8097256B2
(en)
|
2006-09-28 |
2012-01-17 |
Cedars-Sinai Medical Center |
Cancer vaccines and vaccination methods
|
JP5779090B2
(ja)
|
2008-04-09 |
2015-09-16 |
マックスサイト インコーポレーティッド |
新規に単離された細胞の治療組成物の操作および送達
|
DK2328923T3
(en)
|
2008-09-02 |
2016-03-21 |
Cedars Sinai Medical Center |
CD133 epitopes
|
WO2010099205A1
(en)
*
|
2009-02-24 |
2010-09-02 |
The Trustees Of The University Of Pennsylvania |
Methods for treating progressive multifocal leukoencephalopathy (pml)
|
US10426740B1
(en)
|
2010-08-18 |
2019-10-01 |
Avm Biotechnology, Llc |
Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues
|
EP3514170A1
(en)
|
2010-10-22 |
2019-07-24 |
Dana-Farber Cancer Institute, Inc. |
Discovery of regulatory t cells programmed to suppress an immune response
|
TR201820015T4
(tr)
*
|
2010-12-09 |
2019-01-21 |
Univ Pennsylvania |
Kanser Tedavisi İçin Kimerik Antijen Reseptörü-Modifiye Edilmiş T Hücrelerinin Kullanılması
|
EP3246416B1
(en)
|
2011-04-15 |
2024-06-05 |
The Johns Hopkins University |
Safe sequencing system
|
AU2012325915A1
(en)
*
|
2011-10-20 |
2014-04-24 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-CD22 chimeric antigen receptors
|
US9272002B2
(en)
*
|
2011-10-28 |
2016-03-01 |
The Trustees Of The University Of Pennsylvania |
Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
|
WO2013126729A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Use of the cd2 signaling domain in second-generation chimeric antigen receptors
|
BR112014020499A2
(pt)
|
2012-02-22 |
2019-09-24 |
Univ Pennsylvania |
sequência de ácido nucleico isolada, célula - t, vetor, e, população persistente de células - t
|
NZ628804A
(en)
|
2012-02-24 |
2017-08-25 |
Abbvie Stemcentrx Llc |
Dll3 modulators and methods of use
|
AU2013235726B2
(en)
*
|
2012-03-23 |
2017-04-20 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mesothelin chimeric antigen receptors
|
EA033110B1
(ru)
|
2012-04-11 |
2019-08-30 |
Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез |
Химерный рецептор антигена, направленный на антиген созревания b-клеток, кодирующая его нуклеиновая кислота, соответствующие экспрессионный вектор, клетка-хозяин, применения и способы
|
AU2013266733B2
(en)
|
2012-05-25 |
2018-07-05 |
Cellectis |
Methods for engineering allogeneic and immunosuppressive resistant T cell for immunotherapy
|
JP2015523386A
(ja)
*
|
2012-07-13 |
2015-08-13 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
寛容を誘導するために正常b細胞を枯渇させるためのcart19の使用
|
IN2014DN11156A
(zh)
*
|
2012-07-13 |
2015-10-02 |
Univ Pennsylvania |
|
PL4019041T3
(pl)
*
|
2012-07-13 |
2023-05-08 |
The Trustees Of The University Of Pennsylvania |
Kontrola toksyczności wobec aktywności przeciwnowotworowej CAR
|
US20160235787A1
(en)
*
|
2012-07-13 |
2016-08-18 |
The Trustees Of The University Of Pennsylvania |
Epitope Spreading Associated with CAR T-Cells
|
EA201590208A1
(ru)
|
2012-07-13 |
2015-11-30 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Усиление активности т-клеток car путем совместного введения биспецифического антитела
|
KR20150030724A
(ko)
*
|
2012-07-13 |
2015-03-20 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
Car t 세포를 조절하기 위한 조성물 및 방법
|
WO2014031687A1
(en)
*
|
2012-08-20 |
2014-02-27 |
Jensen, Michael |
Method and compositions for cellular immunotherapy
|
ES2714523T3
(es)
*
|
2012-09-04 |
2019-05-28 |
Cellectis |
Receptor quimérico de antígenos multicatenario y usos del mismo
|
CA2885761C
(en)
*
|
2012-09-27 |
2021-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Mesothelin antibodies and methods for eliciting potent antitumor activity
|
US10548957B2
(en)
|
2012-09-28 |
2020-02-04 |
Dana-Farber Cancer Institute, Inc. |
Targeted expansion of Qa-1-peptide-specific regulatory CD8 T cells to ameliorate arthritis
|
EP2904106A4
(en)
*
|
2012-10-01 |
2016-05-11 |
Univ Pennsylvania |
COMPOSITIONS AND METHODS FOR TARGETING STROMAL CELLS FOR THE TREATMENT OF CANCER
|
WO2014055657A1
(en)
|
2012-10-05 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Use of a trans-signaling approach in chimeric antigen receptors
|
US9598489B2
(en)
|
2012-10-05 |
2017-03-21 |
The Trustees Of The Univeristy Of Pennsylvania |
Human alpha-folate receptor chimeric antigen receptor
|
ES2718903T3
(es)
*
|
2012-10-24 |
2019-07-05 |
Us Health |
Receptores de antígenos quiméricos M971
|
EP2912468B1
(en)
|
2012-10-29 |
2018-09-12 |
The Johns Hopkins University |
Papanicolaou test for ovarian and endometrial cancers
|
AU2013204922B2
(en)
*
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
AU2015210373B2
(en)
*
|
2012-12-20 |
2017-04-06 |
Celgene Corporation |
Chimeric antigen receptors
|
JP6467661B2
(ja)
*
|
2013-02-06 |
2019-02-13 |
セルジーン コーポレイション |
改善された特異性を有する改変型tリンパ球
|
US20140234351A1
(en)
|
2013-02-14 |
2014-08-21 |
Immunocellular Therapeutics, Ltd. |
Cancer vaccines and vaccination methods
|
KR102132246B1
(ko)
|
2013-02-15 |
2020-07-09 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
키메라 항원 수용체 및 이의 이용 방법
|
ES2814962T3
(es)
|
2013-02-20 |
2021-03-29 |
Novartis Ag |
Fijación eficaz como objetivo de la leucemia humana primaria utilizando células T modificadas con receptor de antígeno quimérico anti-CD123
|
US9394368B2
(en)
|
2013-02-20 |
2016-07-19 |
Novartis Ag |
Treatment of cancer using humanized anti-EGFRvIII chimeric antigen receptor
|
RS58873B1
(sr)
|
2013-02-22 |
2019-08-30 |
Abbvie Stemcentrx Llc |
Antidll3-antitelo-pbd konjugati i njihova upotreba
|
PT2961831T
(pt)
*
|
2013-02-26 |
2020-10-12 |
Memorial Sloan Kettering Cancer Center |
Composições e métodos para imunoterapêutica
|
WO2014138306A1
(en)
*
|
2013-03-05 |
2014-09-12 |
Baylor College Of Medicine |
Engager cells for immunotherapy
|
US9587237B2
(en)
|
2013-03-14 |
2017-03-07 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
US9499855B2
(en)
*
|
2013-03-14 |
2016-11-22 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
EP2970985A1
(en)
*
|
2013-03-14 |
2016-01-20 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to modify cells for therapeutic objectives
|
AU2014236726A1
(en)
*
|
2013-03-14 |
2015-09-17 |
Bellicum Pharmaceuticals, Inc. |
Methods for controlling T cell proliferation
|
EP3569313A1
(en)
|
2013-03-15 |
2019-11-20 |
GPB Scientific, LLC |
On-chip microfluidic processing of particles
|
ES2837628T3
(es)
|
2013-03-15 |
2021-07-01 |
Celgene Corp |
Linfocitos T modificados
|
US9657105B2
(en)
|
2013-03-15 |
2017-05-23 |
City Of Hope |
CD123-specific chimeric antigen receptor redirected T cells and methods of their use
|
JP6857028B2
(ja)
|
2013-03-15 |
2021-04-14 |
メモリアル スローン ケタリング キャンサー センター |
免疫治療のための組成物および方法
|
WO2014145252A2
(en)
|
2013-03-15 |
2014-09-18 |
Milone Michael C |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
EP2971279B1
(en)
|
2013-03-15 |
2019-11-13 |
The Trustees of Princeton University |
Methods and devices for high throughput purification
|
US20150064153A1
(en)
|
2013-03-15 |
2015-03-05 |
The Trustees Of Princeton University |
High efficiency microfluidic purification of stem cells to improve transplants
|
UY35468A
(es)
*
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
US9790282B2
(en)
|
2013-03-25 |
2017-10-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-CD276 polypeptides, proteins, and chimeric antigen receptors
|
CN115028735A
(zh)
|
2013-05-03 |
2022-09-09 |
俄亥俄州创新基金会 |
Cs1-特异性嵌合抗原受体工程化的免疫效应细胞
|
US10260038B2
(en)
|
2013-05-10 |
2019-04-16 |
Whitehead Institute For Biomedical Research |
Protein modification of living cells using sortase
|
US11077144B2
(en)
|
2013-05-13 |
2021-08-03 |
Cellectis |
CD19 specific chimeric antigen receptor and uses thereof
|
SG11201508805UA
(en)
*
|
2013-05-13 |
2015-11-27 |
Cellectis |
Cd19 specific chimeric antigen receptor and uses thereof
|
US11311575B2
(en)
*
|
2013-05-13 |
2022-04-26 |
Cellectis |
Methods for engineering highly active T cell for immunotherapy
|
CA2911961A1
(en)
|
2013-05-14 |
2014-11-20 |
Board Of Regents, The University Of Texas System |
Human application of engineered chimeric antigen receptor (car) t-cells
|
SG11201509609SA
(en)
|
2013-05-24 |
2015-12-30 |
Univ Texas |
Chimeric antigen receptor-targeting monoclonal antibodies
|
AU2014278323B2
(en)
|
2013-06-10 |
2020-05-28 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for reducing immunosupression by tumor cells
|
US10208125B2
(en)
|
2013-07-15 |
2019-02-19 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Anti-mucin 1 binding agents and uses thereof
|
CA2922547C
(en)
|
2013-08-28 |
2020-03-10 |
Stemcentrx, Inc. |
Site-specific antibody conjugation methods and compositions
|
CN105722522B
(zh)
|
2013-08-30 |
2021-10-19 |
得克萨斯大学体系董事会 |
用于肿瘤疗法的犬尿氨酸耗竭酶的施用
|
EP3757130A1
(en)
|
2013-09-26 |
2020-12-30 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
AU2014331667B2
(en)
|
2013-10-11 |
2019-08-22 |
Biomed Valley Discoveries, Inc. |
TEM8 antibodies and their use
|
EP3057991B8
(en)
*
|
2013-10-15 |
2019-09-04 |
The Scripps Research Institute |
Chimeric antigen receptor t cell switches and uses thereof
|
JP6734774B2
(ja)
|
2013-10-15 |
2020-08-05 |
ザ スクリプス リサーチ インスティテュート |
ペプチドキメラ抗原受容体t細胞スイッチおよびその使用
|
CA2926267C
(en)
*
|
2013-10-17 |
2023-08-01 |
National University Of Singapore |
Chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors
|
US10144770B2
(en)
|
2013-10-17 |
2018-12-04 |
National University Of Singapore |
Chimeric receptors and uses thereof in immune therapy
|
CN104561069A
(zh)
*
|
2013-10-23 |
2015-04-29 |
深圳先进技术研究院 |
含重组嵌合抗原受体基因表达盒的微环dna重组母质粒、含该表达盒的微环dna及应用
|
US20160280798A1
(en)
|
2013-11-06 |
2016-09-29 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Service |
Alk antibodies, conjugates, and chimeric antigen receptors, and their use
|
AU2014348657A1
(en)
|
2013-11-13 |
2016-05-19 |
Novartis Ag |
mTOR inhibitors for enhancing the immune response
|
EP3074419B1
(en)
|
2013-11-25 |
2018-08-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptors to control hiv infection
|
WO2015077717A1
(en)
|
2013-11-25 |
2015-05-28 |
The Broad Institute Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
|
WO2015085147A1
(en)
|
2013-12-05 |
2015-06-11 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
CN105899531B
(zh)
|
2013-12-06 |
2022-02-25 |
美国卫生和人力服务部 |
胸腺基质淋巴细胞生成素受体特异性的嵌合抗原受体及其使用方法
|
CN106459989B
(zh)
|
2013-12-19 |
2023-02-17 |
诺华股份有限公司 |
人间皮素嵌合抗原受体及其用途
|
AU2014368892B2
(en)
|
2013-12-20 |
2019-06-13 |
Fred Hutchinson Cancer Center |
Tagged chimeric effector molecules and receptors thereof
|
CA2934436A1
(en)
*
|
2013-12-20 |
2015-06-25 |
Cellectis |
Method of engineering multi-input signal sensitive t cell for immunotherapy
|
JP6793902B2
(ja)
|
2013-12-20 |
2020-12-02 |
ノバルティス アーゲー |
調節可能キメラ抗原受容体
|
WO2015095811A2
(en)
|
2013-12-20 |
2015-06-25 |
The Board Institute Inc. |
Combination therapy with neoantigen vaccine
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
EP3094653B1
(en)
*
|
2014-01-13 |
2019-10-23 |
Stephen J. Forman |
Chimeric antigen receptors (cars) having mutations in the fc spacer region and methods for their use
|
US11028143B2
(en)
|
2014-01-21 |
2021-06-08 |
Novartis Ag |
Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
EP3105333B1
(en)
|
2014-02-10 |
2020-04-08 |
Emory University |
Expression of chimeric polypeptide with variable lymphocyte receptors on immune cells and uses for treating cancer
|
EP3505623A1
(en)
*
|
2014-02-14 |
2019-07-03 |
Cellectis |
Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells
|
CA2938887C
(en)
|
2014-02-14 |
2023-04-11 |
Laurence J. N. Cooper |
Chimeric antigen receptors and methods of making
|
EP3104866A4
(en)
*
|
2014-02-14 |
2017-08-02 |
Bellicum Pharmaceuticals, Inc. |
Methods for activating t cells using an inducible chimeric polypeptide
|
MX2016010565A
(es)
|
2014-02-14 |
2017-05-10 |
Immune Design Corp |
Inmunoterapia del cancer a través de la combinacion de estimulacion inmunatoria local y sistemica.
|
CA2939711C
(en)
*
|
2014-02-21 |
2020-09-29 |
Cellectis |
Method for in situ inhibition of regulatory t cells
|
KR20170008202A
(ko)
|
2014-02-21 |
2017-01-23 |
애브비 스템센트알엑스 엘엘씨 |
흑색종에 사용하기 위한 항-dll3 항체 및 약물 접합체
|
CN106279434B
(zh)
*
|
2014-02-24 |
2020-07-03 |
西比曼生物科技(上海)有限公司 |
工程化cd20靶向性的nkt细胞及其制备方法和应用
|
US10532088B2
(en)
|
2014-02-27 |
2020-01-14 |
Lycera Corporation |
Adoptive cellular therapy using an agonist of retinoic acid receptor-related orphan receptor gamma and related therapeutic methods
|
CN104877028A
(zh)
*
|
2014-02-28 |
2015-09-02 |
百奥迈科生物技术有限公司 |
抗dota嵌合抗原受体修饰的t细胞及其抗肿瘤的应用
|
ES2758173T3
(es)
*
|
2014-03-05 |
2020-05-04 |
Ucl Business Ltd |
Receptor quimérico de antígeno (CAR) con dominios de unión a antígeno para la región constante de receptores de linfocitos T beta
|
US11385233B2
(en)
|
2015-03-05 |
2022-07-12 |
Autolus Limited |
Methods of depleting malignant T-cells
|
US20230027993A1
(en)
|
2014-03-05 |
2023-01-26 |
Autolus Limited |
Methods
|
GB201403972D0
(en)
|
2014-03-06 |
2014-04-23 |
Ucl Business Plc |
Chimeric antigen receptor
|
CN106163547A
(zh)
|
2014-03-15 |
2016-11-23 |
诺华股份有限公司 |
使用嵌合抗原受体治疗癌症
|
WO2015143224A1
(en)
*
|
2014-03-19 |
2015-09-24 |
Ambrx, Inc. |
Chimeric antigen receptor-modified t-cells
|
US9944709B2
(en)
*
|
2014-03-19 |
2018-04-17 |
Cellectis |
CD123 specific chimeric antigen receptors for cancer immunotherapy
|
CN110841074B
(zh)
|
2014-03-21 |
2023-07-18 |
艾伯维公司 |
抗-egfr抗体及抗体药物偶联物
|
WO2015150526A2
(en)
*
|
2014-04-03 |
2015-10-08 |
Cellectis |
Cd33 specific chimeric antigen receptors for cancer immunotherapy
|
IL293603B2
(en)
|
2014-04-07 |
2024-03-01 |
Novartis Ag |
Cancer treatment using chimeric antigen receptor (CAR) against CD19
|
JP6401292B2
(ja)
*
|
2014-04-07 |
2018-10-10 |
ミネルバ バイオテクノロジーズ コーポレーション |
抗nme抗体
|
MX2016013159A
(es)
*
|
2014-04-10 |
2017-04-27 |
Seattle Children's Hospital (Dba Seattle Children's Res Institute) |
Expresion transgenica regulada por farmaco.
|
EP3131927B8
(en)
|
2014-04-14 |
2020-12-23 |
Cellectis |
Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy
|
ES2759260T3
(es)
|
2014-04-23 |
2020-05-08 |
Juno Therapeutics Inc |
Métodos para aislar, cultivar y modificar genéticametne poblaciones de células inmunes para la terapia adoptiva
|
EP3998278A1
(en)
*
|
2014-04-25 |
2022-05-18 |
2seventy bio, Inc. |
Mnd promoter chimeric antigen receptors
|
EP3134434A4
(en)
*
|
2014-04-25 |
2017-10-25 |
Bluebird Bio, Inc. |
Kappa/lambda chimeric antigen receptors
|
DK3134095T3
(da)
|
2014-04-25 |
2020-06-29 |
Bluebird Bio Inc |
Forbedrede fremgangsmåder til fremstilling af adoptive celleterapier
|
GB2540694A
(en)
*
|
2014-04-29 |
2017-01-25 |
Seattle Children's Hospital (Dba Seattle Children's Res Institute) |
CCR5 disruption of cells expressing anti-hiv chimeric antigen receptor (CAR) derived from broadly neutralizing antibodies
|
CA2947429A1
(en)
|
2014-05-02 |
2015-11-05 |
Emory University |
Humanized variable lymphocyte receptors (vlr) and compositions and uses related thereto
|
EP4008725A1
(en)
|
2014-05-02 |
2022-06-08 |
The Trustees of the University of Pennsylvania |
Compositions and methods of chimeric autoantibody receptor t cells
|
GB201407852D0
(en)
|
2014-05-02 |
2014-06-18 |
Iontas Ltd |
Preparation of libraries od protein variants expressed in eukaryotic cells and use for selecting binding molecules
|
EP3140291A4
(en)
|
2014-05-05 |
2018-01-10 |
Lycera Corporation |
Tetrahydroquinoline sulfonamide and related compounds for use as agonists of rory and the treatment of disease
|
WO2015171558A2
(en)
|
2014-05-05 |
2015-11-12 |
Lycera Corporation |
BENZENESULFONAMIDO AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORγ AND THE TREATEMENT OF DISEASE
|
US10604740B2
(en)
|
2014-05-14 |
2020-03-31 |
Carsgen Therapeutics Limited |
Nucleic acids encoding chimeric antigen receptor proteins which bind epidermal growth factor receptor and T lymphocyte expressing the protein
|
AU2015259877B2
(en)
|
2014-05-15 |
2021-02-25 |
National University Of Singapore |
Modified natural killer cells and uses thereof
|
EP3798233A1
(en)
|
2014-06-02 |
2021-03-31 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Chimeric antigen receptors targeting cd-19
|
RU2719030C2
(ru)
|
2014-06-06 |
2020-04-16 |
Блубёрд Био, Инк. |
Улучшенные композиции на основе t-клеток
|
CA2949325A1
(en)
*
|
2014-06-17 |
2015-12-23 |
Cellectis |
Cd123 specific multi-chain chimeric antigen receptor
|
GB201506423D0
(en)
*
|
2015-04-15 |
2015-05-27 |
Tc Biopharm Ltd |
Gamma delta T cells and uses thereof
|
US10738278B2
(en)
|
2014-07-15 |
2020-08-11 |
Juno Therapeutics, Inc. |
Engineered cells for adoptive cell therapy
|
KR102594343B1
(ko)
*
|
2014-07-21 |
2023-10-26 |
노파르티스 아게 |
Cd33 키메라 항원 수용체를 사용한 암의 치료
|
SG11201700476VA
(en)
|
2014-07-21 |
2017-02-27 |
Novartis Ag |
Treatment of cancer using humanized anti-bcma chimeric antigen receptor
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
JP6736540B2
(ja)
*
|
2014-07-21 |
2020-08-05 |
ノバルティス アーゲー |
Cll−1キメラ抗原受容体を使用した癌の処置
|
NZ728555A
(en)
|
2014-07-24 |
2024-07-26 |
2Seventy Bio Inc |
Bcma chimeric antigen receptors
|
JP2017522884A
(ja)
*
|
2014-07-29 |
2017-08-17 |
ファイザー・インク |
がん免疫療法のためのEGFRvIII特異的キメラ抗原受容体
|
DK3174557T3
(en)
*
|
2014-07-29 |
2019-02-04 |
Cellectis |
ROR1 (NTRKR1) -specific Chimeric Antigen Receptors for Cancer Immunotherapy
|
EP3194432B1
(en)
|
2014-07-31 |
2019-04-10 |
Cellectis |
Ror1 specific multi-chain chimeric antigen receptor
|
EP3660042B1
(en)
|
2014-07-31 |
2023-01-11 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing t-cells
|
US10851149B2
(en)
|
2014-08-14 |
2020-12-01 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using GFR α-4 chimeric antigen receptor
|
CN107108744B
(zh)
|
2014-08-19 |
2020-09-25 |
诺华股份有限公司 |
抗cd123嵌合抗原受体(car)用于癌症治疗
|
US20170269076A1
(en)
|
2014-08-27 |
2017-09-21 |
Dana-Farber Cancer Institute, Inc. |
Intracellular osteopontin regulates the lineage commitment of lymphoid subsets
|
TWI751102B
(zh)
|
2014-08-28 |
2022-01-01 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
EP2990416B1
(en)
*
|
2014-08-29 |
2018-06-20 |
GEMoaB Monoclonals GmbH |
Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
|
WO2016033488A1
(en)
|
2014-08-29 |
2016-03-03 |
Board Of Regents, The University Of Texas System |
Administration of kynurenine depleting enzymes for tumor therapy
|
WO2016036746A1
(en)
*
|
2014-09-02 |
2016-03-10 |
Bellicum Pharmaceuticals, Inc. |
Costimulation of chimeric antigen receptors by myd88 and cd40 polypeptides
|
EP3699188A1
(en)
*
|
2014-09-04 |
2020-08-26 |
Cellectis |
5t4 (tpbg) specific chimeric antigen receptors for cancer immunotherapy
|
US20180133252A9
(en)
|
2014-09-09 |
2018-05-17 |
Unum Therapeutics Inc. |
Chimeric receptors and uses thereof in immune therapy
|
ES2771926T3
(es)
|
2014-09-13 |
2020-07-07 |
Novartis Ag |
Terapias de combinación
|
US10604582B2
(en)
|
2014-09-17 |
2020-03-31 |
The United States Of America, As Represented By The Secretary, Department Of Health |
Anti-CD276 antibodies (B7H3)
|
AU2015317608B2
(en)
|
2014-09-17 |
2021-03-11 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
IL308324A
(en)
|
2014-09-19 |
2024-01-01 |
Hope City |
IL13RA2-targeted chimeric antigen receptor T cells
|
PL3200815T3
(pl)
*
|
2014-10-02 |
2021-10-18 |
The Wistar Institute Of Anatomy And Biology |
Sposoby i kompozycje do leczenia nowotworu
|
JP2017535528A
(ja)
|
2014-10-03 |
2017-11-30 |
ノバルティス アーゲー |
組み合わせ治療
|
CN107109368A
(zh)
|
2014-10-07 |
2017-08-29 |
塞勒克提斯公司 |
用于调节car诱导的免疫细胞活性的方法
|
WO2016057705A1
(en)
|
2014-10-08 |
2016-04-14 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
DK3597742T3
(da)
|
2014-10-09 |
2022-10-03 |
Univ Yamaguchi |
Car-udtrykkende vektor og car-udtrykkende t-celler
|
DK3207130T3
(da)
|
2014-10-14 |
2019-11-11 |
Halozyme Inc |
Sammensætninger af Adenosin Deaminase-2 (ADA2), varianter deraf og fremgangsmåder til anvendelse af samme
|
BR112017008042A2
(pt)
|
2014-10-20 |
2017-12-26 |
Juno Therapeutics Inc |
métodos e composições para dosagem em terapia de célula adotiva
|
KR102583138B1
(ko)
*
|
2014-10-31 |
2023-09-26 |
더 트러스티스 오브 더 유니버시티 오브 펜실베니아 |
T 세포를 자극 및 증대시키는 조성물 및 방법
|
WO2016069283A1
(en)
|
2014-10-31 |
2016-05-06 |
The Trustees Of The University Of Pennsylvania |
Altering gene expression in cart cells and uses thereof
|
WO2016073629A1
(en)
|
2014-11-05 |
2016-05-12 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptors (car) to selectively target protein complexes
|
EP3536707A1
(en)
|
2014-11-05 |
2019-09-11 |
Board of Regents, The University of Texas System |
Gene modified immune effector cells and engineered cells for expansion of immune effector cells
|
PL3215601T3
(pl)
|
2014-11-05 |
2020-11-02 |
Juno Therapeutics, Inc. |
Sposoby transdukcji i przetwarzania komórek
|
WO2016073748A1
(en)
*
|
2014-11-05 |
2016-05-12 |
Board Of Regents, The University Of Texas System |
Biomarkers and targets for cancer immunotherapy
|
US9879087B2
(en)
|
2014-11-12 |
2018-01-30 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
DK3218005T5
(da)
|
2014-11-12 |
2024-10-14 |
Seagen Inc |
Glycan-interagerende forbindelser og anvendelsesfremgangsmåder
|
CN105601746B
(zh)
*
|
2014-11-21 |
2021-02-19 |
三生国健药业(上海)股份有限公司 |
一种嵌合Fc受体的融合蛋白及其制备方法和应用
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
US11266739B2
(en)
|
2014-12-03 |
2022-03-08 |
Juno Therapeutics, Inc. |
Methods and compositions for adoptive cell therapy
|
CN107429253B
(zh)
|
2014-12-05 |
2021-11-05 |
希望之城公司 |
Cs1靶向性嵌合抗原受体修饰的t细胞
|
RU2020120613A
(ru)
|
2014-12-05 |
2021-12-06 |
Мемориал Слоан-Кеттеринг Кэнсер Сентер |
Антитела, нацеленные на рецептор, связанный с g-белками, и способы их применения
|
EP3872094A3
(en)
|
2014-12-05 |
2021-12-08 |
Memorial Sloan Kettering Cancer Center |
Antibodies targeting b-cell maturation antigen and methods of use
|
JP6997620B2
(ja)
*
|
2014-12-05 |
2022-02-04 |
メモリアル スローン ケタリング キャンサー センター |
B細胞成熟抗原を標的化するキメラ抗原受容体およびその使用
|
SG11201704547RA
(en)
|
2014-12-05 |
2017-07-28 |
Memorial Sloan Kettering Cancer Center |
Chimeric antigen receptors targeting g-protein coupled receptor and uses thereof
|
DK3597663T3
(da)
*
|
2014-12-08 |
2022-06-27 |
Us Health |
Kimære antigenreceptorer af anti-cd70
|
HUE046815T2
(hu)
|
2014-12-12 |
2020-03-30 |
Bluebird Bio Inc |
BCMA kiméra antigén receptorok
|
WO2016094783A1
(en)
|
2014-12-12 |
2016-06-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the production of scaav
|
EP3234120A4
(en)
|
2014-12-15 |
2018-05-16 |
The Regents of the University of California |
Cytotoxic molecules responsive to intracellular ligands for selective t cell mediated killing
|
EP3240805A4
(en)
|
2014-12-15 |
2018-05-09 |
The Regents of the University of California |
Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20
|
US10993997B2
(en)
|
2014-12-19 |
2021-05-04 |
The Broad Institute, Inc. |
Methods for profiling the t cell repertoire
|
EP3234193B1
(en)
|
2014-12-19 |
2020-07-15 |
Massachusetts Institute of Technology |
Molecular biomarkers for cancer immunotherapy
|
WO2016102965A1
(en)
*
|
2014-12-24 |
2016-06-30 |
Ucl Business Plc |
Cell
|
SG11201705293WA
(en)
*
|
2014-12-29 |
2017-07-28 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
MA41346A
(fr)
|
2015-01-12 |
2017-11-21 |
Juno Therapeutics Inc |
Eléments régulateurs post-transcriptionnels d'hépatite modifiée
|
US11459390B2
(en)
|
2015-01-16 |
2022-10-04 |
Novartis Ag |
Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor
|
TW202126682A
(zh)
|
2015-01-16 |
2021-07-16 |
美商奇諾治療有限公司 |
針對ror1之特異性抗體及嵌合抗原受體
|
AU2016212161A1
(en)
|
2015-01-26 |
2017-07-13 |
Cellectis |
CLL1-specific multi-chain chimeric antigen receptor
|
CA2975384A1
(en)
*
|
2015-01-29 |
2016-08-04 |
Regents Of The University Of Minnesota |
Chimeric antigen receptors, compositions, and methods
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
HRP20220890T1
(hr)
*
|
2015-02-06 |
2022-10-14 |
National University Of Singapore |
Postupci za povećanje učinkovitosti terapijskih imunosnih stanica
|
JP6724023B2
(ja)
|
2015-02-09 |
2020-07-15 |
リサーチ ディベロップメント ファウンデーション |
改善された補体活性化を示す操作された免疫グロブリンfcポリペプチド
|
US20160228544A1
(en)
*
|
2015-02-11 |
2016-08-11 |
Ensysce Biosciences, Inc. |
Single Walled Carbon Nanotube Polynucleotide Complexes and Methods Related Thereto
|
US11248058B2
(en)
*
|
2015-02-19 |
2022-02-15 |
University Of Florida Research Foundation, Inc. |
Chimeric antigen receptors and uses thereof
|
EP3258967A4
(en)
|
2015-02-20 |
2018-10-03 |
Ohio State Innovation Foundation |
Bivalent antibody directed against nkg2d and tumor associated antigens
|
MA41613A
(fr)
*
|
2015-02-23 |
2018-01-02 |
Abbvie Stemcentrx Llc |
Récepteurs antigéniques chimériques anti-dll3 et procédés d'utilisation desdits récepteurs
|
EP3804741A3
(en)
|
2015-02-24 |
2021-07-14 |
Board of Regents, The University of Texas System |
Selection methods for genetically-modified t cells
|
EP3262166A4
(en)
|
2015-02-24 |
2018-08-15 |
The Regents of The University of California |
Binding-triggered transcriptional switches and methods of use thereof
|
EP3261651B1
(en)
*
|
2015-02-27 |
2022-05-04 |
iCell Gene Therapeutics LLC |
Chimeric antigen receptors (cars) targeting hematologic malignancies, compositions and methods of use thereof
|
EP3089761B1
(en)
|
2015-03-02 |
2019-06-12 |
Innovative Cellular Therapeutics Co., Ltd. |
Reducing immune tolerance induced by pd l1
|
US10195272B2
(en)
|
2015-03-02 |
2019-02-05 |
The Nemours Foundation |
Adoptive t-cell therapy using FcεRI-based chimeric antigen receptors for treating IgE-mediated allergic diseases
|
AU2016226022B2
(en)
*
|
2015-03-05 |
2020-07-09 |
Fred Hutchinson Cancer Center |
Immunomodulatory fusion proteins and uses thereof
|
EP3268087A4
(en)
|
2015-03-12 |
2018-08-29 |
The Regents of the University of California |
METHODS FOR TREATING CANCER WITH RORgamma INHIBITORS
|
CN107708710A
(zh)
*
|
2015-03-17 |
2018-02-16 |
嵌合体生物工程公司 |
Smart CAR装置,DE CAR多肽,Side CAR及其使用
|
US10738116B2
(en)
|
2015-03-19 |
2020-08-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Dual specific anti-CD22-anti-CD19 chimeric antigen receptors
|
RS60270B1
(sr)
|
2015-03-20 |
2020-06-30 |
The United States Of America As Represented By The Secretary Department Of Health And Human Services |
Neutralizacija antitela do gp120 i njihova upotreba
|
WO2016154621A1
(en)
|
2015-03-26 |
2016-09-29 |
The California Institute For Biomedical Research |
SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
|
AU2016243124A1
(en)
|
2015-03-27 |
2017-11-02 |
University Of Southern California |
CAR T-cell therapy directed to LHR for the treatment of solid tumors
|
CA2981166A1
(en)
*
|
2015-03-27 |
2016-10-06 |
University Of Southern California |
Hla-g as a novel target for car t-cell immunotherapy
|
EP3277727B1
(en)
*
|
2015-04-02 |
2021-11-03 |
Memorial Sloan Kettering Cancer Center |
Tnfrsf14/ hvem proteins and methods of use thereof
|
RU2754041C2
(ru)
|
2015-04-03 |
2021-08-25 |
Еурека Терапьютикс, Инк. |
Конструкции, направленные на комплексы пептида afp/мнс, и виды их использования
|
CA2981616A1
(en)
|
2015-04-06 |
2016-10-13 |
Subdomain, Llc |
De novo binding domain containing polypeptides and uses thereof
|
WO2016164370A1
(en)
|
2015-04-06 |
2016-10-13 |
Ohio State Innovation Foundation |
Egfr-directed car therapy for glioblastoma
|
BR112017021500A2
(pt)
|
2015-04-08 |
2018-09-25 |
Novartis Ag |
terapias com cd20, terapias com cd22 e terapias de combinação com uma célula que expressa (car) receptor de antígeno quimérico de cd19
|
US11091546B2
(en)
|
2015-04-15 |
2021-08-17 |
The Scripps Research Institute |
Optimized PNE-based chimeric receptor T cell switches and uses thereof
|
WO2016166568A1
(en)
|
2015-04-16 |
2016-10-20 |
Juno Therapeutics Gmbh |
Methods, kits and apparatus for expanding a population of cells
|
WO2016168595A1
(en)
|
2015-04-17 |
2016-10-20 |
Barrett David Maxwell |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
US12128069B2
(en)
|
2015-04-23 |
2024-10-29 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
EP3288638A1
(en)
|
2015-04-25 |
2018-03-07 |
The General Hospital Corporation |
Anti-fugetactic agent and anti-cancer agent combination therapy and compositions for the treatment of cancer
|
WO2016176652A2
(en)
|
2015-04-29 |
2016-11-03 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
EP3995142A3
(en)
*
|
2015-04-29 |
2022-08-24 |
Fred Hutchinson Cancer Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
WO2016176639A1
(en)
*
|
2015-04-30 |
2016-11-03 |
University Of Southern California |
Secretory tnt car cell immunotherapy
|
WO2016174652A1
(en)
*
|
2015-04-30 |
2016-11-03 |
Technion Research & Development Foundation Limited |
Chimeric antigen receptors and methods of their use
|
RU2754661C2
(ru)
|
2015-05-01 |
2021-09-06 |
Дзе Реджентс Оф Дзе Юниверсити Оф Калифорния |
Гликанзависимые иммунотерапевтические молекулы
|
CA2982847A1
(en)
|
2015-05-05 |
2016-11-10 |
Lycera Corporation |
Dihydro-2h-benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of ror.gamma. and the treatment of disease
|
KR20230174291A
(ko)
|
2015-05-06 |
2023-12-27 |
스니프르 테크놀로지스 리미티드 |
미생물 개체군 변경 및 미생물군 변형
|
CA2988854A1
(en)
|
2015-05-08 |
2016-11-17 |
President And Fellows Of Harvard College |
Universal donor stem cells and related methods
|
US11253616B2
(en)
|
2017-09-06 |
2022-02-22 |
The Trustees Of The University Of Pennsylvania |
Small molecules for dual function positron emission tomography (PET) and cell suicide switches
|
US20200316231A1
(en)
*
|
2015-05-10 |
2020-10-08 |
The Trustees Of The University Of Pennsylvania |
Compositions And Methods For Imaging Immune Cells
|
WO2016180467A1
(en)
*
|
2015-05-11 |
2016-11-17 |
Biontech Cell & Gene Therapies Gmbh |
Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination
|
EP3447075B1
(en)
|
2015-05-15 |
2023-08-09 |
The General Hospital Corporation |
Antagonistic anti-tumor necrosis factor receptor superfamily antibodies
|
US20180147271A1
(en)
*
|
2015-05-18 |
2018-05-31 |
Bluebird Bio, Inc. |
Anti-ror1 chimeric antigen receptors
|
ES2819976T5
(es)
|
2015-05-18 |
2024-02-23 |
Tcr2 Therapeutics Inc |
Composiciones y usos médicos para la reprogramación de TCR con proteínas de fusión
|
CR20170584A
(es)
|
2015-05-20 |
2018-03-20 |
Massachusetts Gen Hospital |
Neoantígenos compartidos
|
US10434153B1
(en)
|
2015-05-20 |
2019-10-08 |
Kim Leslie O'Neill |
Use of car and bite technology coupled with an scFv from an antibody against human thymidine kinase 1 to specifically target tumors
|
US10752670B2
(en)
|
2015-05-20 |
2020-08-25 |
Cellectis |
Anti-GD3 specific chimeric antigen receptors for cancer immunotherapy
|
WO2016185443A1
(en)
|
2015-05-20 |
2016-11-24 |
Novartis Ag |
Pharmaceutical combination of everolimus with dactolisib
|
JP7121496B2
(ja)
*
|
2015-05-28 |
2022-08-18 |
アルモ・バイオサイエンシーズ・インコーポレイテッド |
癌治療で使用するためのペグ化インターロイキン-10
|
BR112017025166A2
(pt)
*
|
2015-05-28 |
2018-07-31 |
Kite Pharma Inc |
métodos de condicionar pacientes para terapia de células t
|
BR122023022076A2
(pt)
|
2015-05-28 |
2024-01-16 |
Kite Pharma, Inc. |
Agente pré-condicionantes, seus usos e métodos para identificar uma dose de um ou mais agentes de pré-condicionamento e para verificar a eficácia dos mesmos
|
US20180161369A1
(en)
|
2015-05-29 |
2018-06-14 |
Fred Hutchinson Cancer Research Center |
Compositions for cellular immunotherapy
|
WO2016196388A1
(en)
|
2015-05-29 |
2016-12-08 |
Juno Therapeutics, Inc. |
Composition and methods for regulating inhibitory interactions in genetically engineered cells
|
RS60441B1
(sr)
|
2015-05-30 |
2020-07-31 |
Molecular Templates Inc |
De-imunizovane, strukture shiga toksin a podjedinice i ciljani ćelijski molekuli koji sadrže isti
|
US10711064B2
(en)
|
2015-06-04 |
2020-07-14 |
University Of Southern California |
Lym-1 and Lym-2 targeted CAR cell immunotherapy
|
CN116121236A
(zh)
*
|
2015-06-05 |
2023-05-16 |
诺华股份有限公司 |
基于流通顺磁性颗粒的细胞分离和顺磁性颗粒移除
|
KR20180023949A
(ko)
|
2015-06-09 |
2018-03-07 |
메모리얼 슬로안-케터링 캔서 센터 |
인간 hla에 의해 제시된 ebv 잠복성 막 단백질 2a 펩티드에 특이적인 t 세포 수용체-유사 항체 작용제
|
IL255884B2
(en)
|
2015-06-10 |
2024-05-01 |
Immunitybio Inc |
Modified NK-92 cells for cancer treatment
|
JP6838004B2
(ja)
|
2015-06-11 |
2021-03-03 |
リセラ・コーポレイションLycera Corporation |
RORγのアゴニストとしての使用及び疾患の治療のためのアリールジヒドロ−2H−ベンゾ[b][1,4]オキサジンスルホンアミド及び関連化合物
|
CN105177031B
(zh)
*
|
2015-06-12 |
2018-04-24 |
北京艺妙神州医疗科技有限公司 |
嵌合抗原受体修饰的t细胞及其用途
|
AU2016274989A1
(en)
*
|
2015-06-12 |
2017-11-02 |
Immunomedics, Inc. |
Disease therapy with chimeric antigen receptor (car) constructs and t cells (car-t) or nk cells (car-nk) expressing car constructs
|
AU2016277121C1
(en)
|
2015-06-12 |
2022-07-14 |
Lentigen Technology, Inc. |
Method to treat cancer with engineered T-cells
|
EP3436575A1
(en)
|
2015-06-18 |
2019-02-06 |
The Broad Institute Inc. |
Novel crispr enzymes and systems
|
ES2976647T3
(es)
*
|
2015-06-19 |
2024-08-06 |
Sebastian Kobold |
Proteínas de fusión PD-1-CD28 y su uso en medicina
|
US11173179B2
(en)
|
2015-06-25 |
2021-11-16 |
Icell Gene Therapeutics Llc |
Chimeric antigen receptor (CAR) targeting multiple antigens, compositions and methods of use thereof
|
CA2990177A1
(en)
|
2015-06-25 |
2016-12-29 |
Icell Gene Therapeutics Llc |
Chimeric antigen receptors (cars), compositions and methods thereof
|
WO2017004252A1
(en)
|
2015-06-30 |
2017-01-05 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Redirected cells with mhc chimeric receptors and methods of use in immunotherapy
|
MA42902A
(fr)
*
|
2015-07-08 |
2018-05-16 |
Univ Johns Hopkins |
Lymphocytes infiltrant la moelle (mil) en tant que source de lymphocytes t pour une thérapie par des récepteurs chimériques d'un antigène (car)
|
WO2017011316A1
(en)
*
|
2015-07-10 |
2017-01-19 |
The Trustees Of The University Of Pennsylvania |
Treatment of a canine cd20 positive disease or condition using a canine cd20-specific chimeric antigen receptor
|
MA42895A
(fr)
|
2015-07-15 |
2018-05-23 |
Juno Therapeutics Inc |
Cellules modifiées pour thérapie cellulaire adoptive
|
CN109476722A
(zh)
*
|
2015-07-21 |
2019-03-15 |
诺华股份有限公司 |
用于改善免疫细胞的功效和扩张的方法
|
US10493139B2
(en)
*
|
2015-07-24 |
2019-12-03 |
Innovative Cellular Therapeutics CO., LTD. |
Humanized anti-CD19 antibody and use thereof with chimeric antigen receptor
|
WO2017019848A1
(en)
|
2015-07-28 |
2017-02-02 |
The Trustees Of The University Of Pennsylvania |
Modified monocytes/macrophage expressing chimeric antigen receptors and uses thereof
|
US20170119820A1
(en)
|
2015-07-31 |
2017-05-04 |
Regents Of The University Of Minnesota |
Modified cells and methods of therapy
|
ES2877090T3
(es)
|
2015-08-05 |
2021-11-16 |
Cellabmed Inc |
Receptor de antígenos quiméricos y células T en las que se expresa el receptor de antígenos quiméricos
|
WO2017027291A1
(en)
|
2015-08-07 |
2017-02-16 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Bispecific car t-cells for solid tumor targeting
|
WO2017027392A1
(en)
|
2015-08-07 |
2017-02-16 |
Novartis Ag |
Treatment of cancer using chimeric cd3 receptor proteins
|
WO2017027653A1
(en)
|
2015-08-11 |
2017-02-16 |
The Johns Hopkins University |
Assaying ovarian cyst fluid
|
US11352439B2
(en)
|
2015-08-13 |
2022-06-07 |
Kim Leslie O'Neill |
Macrophage CAR (MOTO-CAR) in immunotherapy
|
CN106467906B
(zh)
*
|
2015-08-20 |
2019-09-27 |
北京马力喏生物科技有限公司 |
构建体、转基因淋巴细胞及其制备方法和用途
|
US10976232B2
(en)
|
2015-08-24 |
2021-04-13 |
Gpb Scientific, Inc. |
Methods and devices for multi-step cell purification and concentration
|
EP4218777A3
(en)
*
|
2015-08-28 |
2023-08-23 |
The Trustees of the University of Pennsylvania |
Methods and compositions for cells expressing a chimeric intracellular signaling molecule
|
CN108135932A
(zh)
*
|
2015-08-28 |
2018-06-08 |
宾夕法尼亚大学董事会 |
表达嵌合细胞内信号传导分子的细胞的方法和组合物
|
WO2017040380A2
(en)
|
2015-08-28 |
2017-03-09 |
Research Development Foundation |
Engineered antibody fc variants
|
ES2911015T3
(es)
|
2015-08-31 |
2022-05-17 |
Helixmith Co Ltd |
Receptores quiméricos de antígeno anti-sialil Tn
|
CN108780084B
(zh)
|
2015-09-03 |
2022-07-22 |
诺华股份有限公司 |
预测细胞因子释放综合征的生物标志物
|
US12121539B2
(en)
*
|
2015-09-11 |
2024-10-22 |
Biosceptre (Aust) Pty Ltd |
Chimeric antigen receptors and uses thereof
|
MA44909A
(fr)
|
2015-09-15 |
2018-07-25 |
Acerta Pharma Bv |
Association thérapeutique d'un inhibiteur du cd19 et d'un inhibiteur de la btk
|
US11890348B2
(en)
|
2015-09-18 |
2024-02-06 |
The General Hospital Corporation |
Localized delivery of anti-fugetactic agent for treatment of cancer
|
CA2999096A1
(en)
*
|
2015-09-18 |
2017-03-23 |
The General Hospital Corporation Dba Massachusetts General Hospital |
Modified t-cells having anti-fugetactic properties and uses thereof
|
EP3353197A4
(en)
*
|
2015-09-22 |
2018-11-14 |
The Trustees of The University of Pennsylvania |
Method of redirecting t cells to treat hiv infection
|
CN108289954B
(zh)
|
2015-09-24 |
2022-05-31 |
阿布维特罗有限责任公司 |
Hiv抗体组合物和使用方法
|
CN113774495A
(zh)
|
2015-09-25 |
2021-12-10 |
阿布维特罗有限责任公司 |
用于对天然配对t细胞受体序列进行t细胞受体靶向鉴别的高通量方法
|
JP2018534264A
(ja)
|
2015-09-28 |
2018-11-22 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
自己免疫および同種免疫への治療的介入としてのキメラ抗原受容体(car)t細胞
|
US11365391B2
(en)
|
2015-09-28 |
2022-06-21 |
Trustees Of Dartmouth College |
Chimeric antigen receptor anti-inflammatory cells and methods of use
|
AU2016336515B2
(en)
*
|
2015-10-06 |
2023-08-24 |
City Of Hope |
Chimeric antigen receptors targeted to PSCA
|
EP3359570A1
(en)
|
2015-10-07 |
2018-08-15 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Il-7r-alpha specific antibodies for treating acute lymphoblastic leukemia
|
WO2017059796A1
(en)
|
2015-10-08 |
2017-04-13 |
Shanghai Sidansai Biotechnology Co., Ltd |
Activation and expansion of t cells
|
WO2017061615A1
(ja)
*
|
2015-10-08 |
2017-04-13 |
国立大学法人名古屋大学 |
キメラ抗原受容体を発現する遺伝子改変t細胞の調製方法
|
CN105153315B
(zh)
*
|
2015-10-09 |
2019-04-02 |
重庆精准生物技术有限公司 |
免疫抑制受体联合肿瘤抗原嵌合受体及其应用
|
JP6991134B2
(ja)
*
|
2015-10-09 |
2022-01-12 |
ガーダント ヘルス, インコーポレイテッド |
無細胞dnaを使用する集団ベースの処置レコメンダ
|
WO2017069958A2
(en)
|
2015-10-09 |
2017-04-27 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
WO2017062820A1
(en)
*
|
2015-10-09 |
2017-04-13 |
Miltenyi Biotec Technology, Inc. |
Chimeric antigen receptors and methods of use
|
CN105924530B
(zh)
*
|
2015-10-13 |
2019-08-06 |
中国人民解放军总医院 |
嵌合抗原受体及其基因和重组表达载体、car20-nkt细胞及其制备方法和应用
|
CN106755023A
(zh)
*
|
2015-10-15 |
2017-05-31 |
中国人民解放军军事医学科学院附属医院 |
带安全开关的嵌合抗原受体免疫细胞及其制备方法与应用
|
DK3362569T3
(da)
|
2015-10-16 |
2021-10-18 |
Univ Muenchen Ludwig Maximilians |
Cxcr6-transducerede t-celler til målrettet tumorterapi
|
IL300420B2
(en)
|
2015-10-16 |
2024-09-01 |
Univ Columbia |
Preparations and methods for inhibiting antigens of a certain lineage
|
CN108601850A
(zh)
|
2015-10-19 |
2018-09-28 |
马萨诸塞大学 |
抗癌和抗炎症治疗及其方法
|
TW202317758A
(zh)
|
2015-10-20 |
2023-05-01 |
美商凱特製藥公司 |
製備用於t細胞治療之t細胞的方法
|
MA45488A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés, kits et appareil de culture de cellules
|
MA45426A
(fr)
|
2015-10-22 |
2019-05-01 |
Juno Therapeutics Gmbh |
Procédés, kits, agents et appareils de transduction
|
MA45489A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés de culture de cellules, kits et appareil associés
|
CN105132445B
(zh)
*
|
2015-10-23 |
2018-10-02 |
马健颖 |
一种特异识别肿瘤细胞的受体蛋白、t淋巴细胞及nk细胞
|
US20170112878A1
(en)
*
|
2015-10-23 |
2017-04-27 |
Sorrento Therapeutics, Inc. |
Programmable universal cell receptors and method of using the same
|
EP3368075B1
(en)
|
2015-10-27 |
2020-01-29 |
Board of Regents, The University of Texas System |
Chimeric antigen receptor molecules and uses thereof
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
EP3368689B1
(en)
|
2015-10-28 |
2020-06-17 |
The Broad Institute, Inc. |
Composition for modulating immune responses by use of immune cell gene signature
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
MA44314A
(fr)
*
|
2015-11-05 |
2018-09-12 |
Juno Therapeutics Inc |
Récepteurs chimériques contenant des domaines induisant traf, et compositions et méthodes associées
|
WO2017079703A1
(en)
|
2015-11-05 |
2017-05-11 |
Juno Therapeutics, Inc. |
Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy
|
CN116217729A
(zh)
|
2015-11-12 |
2023-06-06 |
思进公司 |
聚糖相互作用化合物及使用方法
|
CN105331585A
(zh)
*
|
2015-11-13 |
2016-02-17 |
科济生物医药(上海)有限公司 |
携带pd-l1阻断剂的嵌合抗原受体修饰的免疫效应细胞
|
CN105384826A
(zh)
*
|
2015-11-19 |
2016-03-09 |
广州熙帝生物科技有限公司 |
表达嵌合抗原受体的脐血有核细胞及其应用
|
EP3377086B1
(en)
|
2015-11-19 |
2024-05-01 |
The Brigham and Women's Hospital, Inc. |
Lymphocyte antigen cd5-like (cd5l)-interleukin 12b (p40) heterodimers in immunity
|
EP3380117B1
(en)
|
2015-11-27 |
2021-01-06 |
Cartherics Pty. Ltd. |
Genetically modified cells and uses thereof
|
MA43378A
(fr)
|
2015-12-03 |
2018-10-10 |
Juno Therapeutics Inc |
Compositions et méthodes pour la reduction de la réponse immunitaire contre récepteurs d'antigène chimériques
|
CA3007262A1
(en)
|
2015-12-03 |
2017-06-08 |
Lucas James Thompson |
Modified chimeric receptors and related compositions and methods
|
AU2016362129A1
(en)
|
2015-12-04 |
2018-06-14 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
WO2017096331A1
(en)
|
2015-12-04 |
2017-06-08 |
Juno Therapeutics, Inc. |
Methods and compositions related to toxicity associated with cell therapy
|
WO2017095525A1
(en)
*
|
2015-12-04 |
2017-06-08 |
David Scott |
Antigen-specific t cells for inducing immune tolerance
|
WO2017099712A1
(en)
|
2015-12-07 |
2017-06-15 |
Bluebird Bio, Inc. |
Improved t cell compositions
|
JP6958820B2
(ja)
|
2015-12-14 |
2021-11-02 |
エックス4 ファーマシューティカルズ, インコーポレイテッド |
がんを処置する方法
|
JP6864296B2
(ja)
|
2015-12-14 |
2021-04-28 |
エックス4 ファーマシューティカルズ, インコーポレイテッド |
がんを処置する方法
|
US11413340B2
(en)
|
2015-12-22 |
2022-08-16 |
Novartis Ag |
Mesothelin chimeric antigen receptor (CAR) and antibody against PD-L1 inhibitor for combined use in anticancer therapy
|
US10610527B2
(en)
|
2015-12-22 |
2020-04-07 |
X4 Pharmaceuticals, Inc. |
Methods for treating immunodeficiency disease
|
CA3009709A1
(en)
|
2015-12-30 |
2017-07-06 |
Novartis Ag |
Immune effector cell therapies with enhanced efficacy
|
CN116334113A
(zh)
|
2016-01-08 |
2023-06-27 |
加利福尼亚大学董事会 |
有条件活性的异二聚体多肽及其使用方法
|
GB201600328D0
(en)
|
2016-01-08 |
2016-02-24 |
Univ Oslo Hf |
Anti-CD37 chimeric antigen receptors and immune cells expressing them
|
CN105950645A
(zh)
*
|
2016-01-11 |
2016-09-21 |
灏灵赛奥(天津)生物科技有限公司 |
Car-cd19抗原受体的人源化融合基因片段、其构建方法及应用
|
US11505599B2
(en)
|
2016-01-14 |
2022-11-22 |
Memorial Sloan-Kettering Cancer Center |
T cell receptor-like antibodies specific for Foxp3-derived peptides
|
WO2017123911A1
(en)
*
|
2016-01-15 |
2017-07-20 |
The Wistar Institute Of Anatomy And Biology |
Methods and compositions for treating cancer
|
JP2019506398A
(ja)
|
2016-01-21 |
2019-03-07 |
ファイザー・インク |
上皮増殖因子受容体変異体iiiおよびcd3の単一および二重特異性抗体およびそれらの使用
|
RU2751662C2
(ru)
|
2016-01-21 |
2021-07-15 |
Пфайзер Инк. |
Химерные антигенные рецепторы, нацеливающиеся на вариант iii рецептора эпидермального фактора роста
|
CN105567640A
(zh)
*
|
2016-01-27 |
2016-05-11 |
苏州佰通生物科技有限公司 |
一种嵌合抗原受体脂肪干细胞及其制备方法
|
EA201891717A1
(ru)
|
2016-02-23 |
2019-02-28 |
Иммьюн Дизайн Корп. |
Препараты мультигеномных ретровирусных векторов и способы и системы для их получения и применения
|
EP3423483A4
(en)
|
2016-03-02 |
2019-08-21 |
Board Of Regents Of the University Of Texas System |
VARIANTS OF HUMAN ENZYME KYNURENINASE HAVING IMPROVED PHARMACOLOGICAL PROPERTIES
|
KR20180118175A
(ko)
|
2016-03-04 |
2018-10-30 |
노파르티스 아게 |
다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도
|
EP3430130B1
(en)
|
2016-03-14 |
2023-01-04 |
Wisconsin Alumni Research Foundation |
Methods of t cell expansion and activation
|
EP3430548A1
(en)
|
2016-03-16 |
2019-01-23 |
Juno Therapeutics, Inc. |
Methods for determining dosing of a therapeutic agent and related treatments
|
EP3430549A1
(en)
|
2016-03-16 |
2019-01-23 |
Juno Therapeutics, Inc. |
Methods for adaptive design of a treatment regimen and related treatments
|
CA3017442A1
(en)
*
|
2016-03-17 |
2017-09-21 |
Yamaguchi University |
Immunocompetent cell and expression vector expressing regulatory factors of immune function
|
US10875927B2
(en)
|
2016-03-18 |
2020-12-29 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for CD20 immunotherapy
|
MX2018011480A
(es)
|
2016-03-22 |
2019-03-28 |
Seattle Children´S Hospital Dba Seattle Children´S Res Institute |
Metodos de intervencion temprana para prevenir o aminorar toxicidad.
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
CN113082201B
(zh)
|
2016-04-01 |
2024-07-05 |
上海斯丹赛生物技术有限公司 |
刺激t细胞介导的对表达抗原的细胞群的免疫应答的方法
|
HRP20221348T1
(hr)
|
2016-04-01 |
2023-01-06 |
Kite Pharma, Inc. |
Kimerni receptori i postupci njihove uporabe
|
CU20180120A7
(es)
|
2016-04-01 |
2019-05-03 |
Kite Pharma Inc |
Moléculas de unión a bcma
|
US10654934B2
(en)
|
2016-04-01 |
2020-05-19 |
Innovative Cellular Therapeutics CO., LTD. |
Use of chimeric antigen receptor modified cells to treat cancer
|
MX2018012017A
(es)
|
2016-04-01 |
2019-07-04 |
Kite Pharma Inc |
Antigeno quimerico y receptores de celulas t y metodos de uso.
|
CA3019655A1
(en)
|
2016-04-01 |
2017-10-05 |
Amgen Inc. |
Chimeric receptors to flt3 and methods of use thereof
|
CN109153722A
(zh)
|
2016-04-08 |
2019-01-04 |
X4 制药有限公司 |
用于治疗癌症的方法
|
US11859208B2
(en)
|
2016-04-08 |
2024-01-02 |
Emory University |
Methods of treating cancer using cell based therapies
|
EP3443001A4
(en)
|
2016-04-11 |
2020-04-29 |
Obsidian Therapeutics, Inc. |
REGULATED BIOCIRCUIT SYSTEMS
|
CN106399255B
(zh)
*
|
2016-04-13 |
2019-10-18 |
阿思科力(苏州)生物科技有限公司 |
Pd-1 car-t细胞及其制备方法和应用
|
US10188749B2
(en)
|
2016-04-14 |
2019-01-29 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
JP7497955B6
(ja)
|
2016-04-15 |
2024-07-01 |
ノバルティス アーゲー |
選択的タンパク質発現のための組成物および方法
|
KR20230051601A
(ko)
|
2016-04-15 |
2023-04-18 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Icos 리간드 변이체 면역조절 단백질 및 그의 용도
|
NZ746934A
(en)
|
2016-04-15 |
2023-11-24 |
Alpine Immune Sciences Inc |
Cd80 variant immunomodulatory proteins and uses thereof
|
US20190346442A1
(en)
|
2016-04-18 |
2019-11-14 |
The Broad Institute, Inc. |
Improved hla epitope prediction
|
CN105907719B
(zh)
*
|
2016-04-18 |
2019-10-18 |
阿思科力(苏州)生物科技有限公司 |
Anti ROBO1 CAR-T细胞及其制备和应用
|
KR102529012B1
(ko)
|
2016-04-22 |
2023-05-09 |
크라제 메디컬 씨오 리미티드 |
세포성 면역요법을 위한 조성물 및 방법
|
WO2017192536A1
(en)
|
2016-05-02 |
2017-11-09 |
University Of Kansas |
Eliminating mhc restriction from the t cell receptor as a strategy for immunotherapy
|
MA44869A
(fr)
|
2016-05-06 |
2019-03-13 |
Editas Medicine Inc |
Cellules génétiquement modifiées et leurs procédés de fabrication
|
US11261223B2
(en)
*
|
2016-05-11 |
2022-03-01 |
The University Of Chicago |
Methods of treating cancers with CT45 targeted therapies
|
CN109689677B
(zh)
|
2016-05-27 |
2023-11-10 |
阿迪根有限公司 |
用于基因组编辑分子的细胞内递送的肽和纳米颗粒
|
CA3025516A1
(en)
*
|
2016-05-27 |
2017-11-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Flt3-specific chimeric antigen receptors and methods using same
|
CN105837693A
(zh)
*
|
2016-05-30 |
2016-08-10 |
李斯文 |
一种基于bcma的抗原嵌合受体及其制备方法和应用
|
US20210177896A1
(en)
|
2016-06-02 |
2021-06-17 |
Novartis Ag |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
JP2019517518A
(ja)
|
2016-06-03 |
2019-06-24 |
メモリアル スローン ケタリング キャンサー センター |
早期治療選択肢としての養子細胞療法
|
GB201609811D0
(en)
|
2016-06-05 |
2016-07-20 |
Snipr Technologies Ltd |
Methods, cells, systems, arrays, RNA and kits
|
MA45341A
(fr)
|
2016-06-06 |
2019-04-10 |
Hutchinson Fred Cancer Res |
Procédés de traitement de malignités de lymphocytes b au moyen d'une thérapie cellulaire adoptive
|
WO2017213979A1
(en)
*
|
2016-06-06 |
2017-12-14 |
St. Jude Children's Research Hospital |
Anti-cd7 chimeric antigen receptor and method of use thereof
|
JP2019524651A
(ja)
|
2016-06-08 |
2019-09-05 |
アッヴィ・インコーポレイテッド |
抗cd98抗体及び抗体薬物コンジュゲート
|
BR112018075644A2
(pt)
|
2016-06-08 |
2019-04-09 |
Abbvie Inc. |
anticorpos anti-cd98 e conjugados de anticorpo e fármaco
|
BR112018075651A2
(pt)
|
2016-06-08 |
2019-04-09 |
Abbvie Inc. |
anticorpos anti-cd98 e conjugados anticorpo fármaco
|
SG11201810640RA
(en)
|
2016-06-08 |
2018-12-28 |
Intrexon Corp |
Cd33 specific chimeric antigen receptors
|
SG11201811193TA
(en)
|
2016-06-08 |
2019-01-30 |
Abbvie Inc |
Anti-b7-h3 antibodies and antibody drug conjugates
|
JP2019521973A
(ja)
|
2016-06-08 |
2019-08-08 |
アッヴィ・インコーポレイテッド |
抗bh7−h3抗体及び抗体薬物コンジュゲート
|
US20200002421A1
(en)
|
2016-06-08 |
2020-01-02 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
CN107523545A
(zh)
*
|
2016-06-20 |
2017-12-29 |
上海细胞治疗研究院 |
一种高效稳定表达抗体的杀伤性细胞及其用途
|
WO2017223229A1
(en)
|
2016-06-21 |
2017-12-28 |
X4 Pharmaceuticals, Inc. |
Cxcr4 inhibitors and uses thereof
|
WO2017223243A1
(en)
|
2016-06-21 |
2017-12-28 |
X4 Pharmaceuticals, Inc. |
Cxcr4 inhibitors and uses thereof
|
EP3471727B1
(en)
|
2016-06-21 |
2020-12-09 |
X4 Pharmaceuticals, Inc. |
Cxcr4 inhibitors and uses thereof
|
EP4353750A3
(en)
|
2016-06-24 |
2024-07-24 |
iCell Gene Therapeutics LLC |
Chimeric antigen receptors (cars), compositions and methods thereof
|
CN106117367B
(zh)
*
|
2016-06-24 |
2020-02-11 |
安徽未名细胞治疗有限公司 |
一种her-3特异性嵌合抗原受体及其应用
|
JP6987134B2
(ja)
|
2016-06-27 |
2021-12-22 |
ジュノー セラピューティクス インコーポレイテッド |
ペプチドエピトープを同定する方法、そのようなエピトープに結合する分子および関連用途
|
MA45491A
(fr)
|
2016-06-27 |
2019-05-01 |
Juno Therapeutics Inc |
Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
|
WO2018002358A1
(en)
|
2016-06-30 |
2018-01-04 |
F. Hoffmann-La Roche Ag |
Improved adoptive t-cell therapy
|
EP4269562A3
(en)
|
2016-07-12 |
2023-12-27 |
Kite Pharma, Inc. |
Antigen binding molecules and methods of use thereof
|
JP2018035137A
(ja)
|
2016-07-13 |
2018-03-08 |
マブイミューン ダイアグノスティックス エイジーMabimmune Diagnostics Ag |
新規な抗線維芽細胞活性化タンパク質(fap)結合薬剤およびその使用
|
WO2018013918A2
(en)
|
2016-07-15 |
2018-01-18 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
PL240585B1
(pl)
*
|
2016-07-18 |
2022-05-02 |
Helix Biopharma Corp |
Chimeryczny receptor antygenowy (CAR), komórki immunologiczne zawierające CAR oraz kompozycja farmaceutyczna je zawierająca do leczenia nowotworów
|
US11365252B2
(en)
|
2016-07-20 |
2022-06-21 |
University Of Utah Research Foundation |
CD229 CAR T cells and methods of use thereof
|
US11384156B2
(en)
|
2016-07-25 |
2022-07-12 |
The Nemours Foundation |
Adoptive T-cell therapy using EMPD-specific chimeric antigen receptors for treating IgE-mediated allergic diseases
|
WO2018022945A1
(en)
|
2016-07-28 |
2018-02-01 |
Alpine Immune Sciences, Inc. |
Cd112 variant immunomodulatory proteins and uses thereof
|
EP3491013A1
(en)
|
2016-07-28 |
2019-06-05 |
Alpine Immune Sciences, Inc. |
Cd155 variant immunomodulatory proteins and uses thereof
|
US11471488B2
(en)
|
2016-07-28 |
2022-10-18 |
Alpine Immune Sciences, Inc. |
CD155 variant immunomodulatory proteins and uses thereof
|
CN110214150A
(zh)
|
2016-07-28 |
2019-09-06 |
诺华股份有限公司 |
嵌合抗原受体和pd-1抑制剂的组合疗法
|
CN109804089A
(zh)
|
2016-07-29 |
2019-05-24 |
朱诺治疗学股份有限公司 |
用于评估复制型病毒存在或不存在的方法
|
AU2017301880C1
(en)
|
2016-07-29 |
2022-04-21 |
Juno Therapeutics, Inc. |
Immunomodulatory polypeptides and related compositions and methods
|
CN110088133B
(zh)
*
|
2016-07-29 |
2023-12-08 |
朱诺治疗学股份有限公司 |
抗独特型抗体及相关方法
|
EP3490590A2
(en)
|
2016-08-01 |
2019-06-05 |
Novartis AG |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
WO2018026953A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
US11078481B1
(en)
|
2016-08-03 |
2021-08-03 |
KSQ Therapeutics, Inc. |
Methods for screening for cancer targets
|
US11630103B2
(en)
|
2016-08-17 |
2023-04-18 |
The Broad Institute, Inc. |
Product and methods useful for modulating and evaluating immune responses
|
EP3506916B1
(en)
|
2016-09-01 |
2021-04-07 |
Chimera Bioengineering Inc. |
Gold optimized car t-cells
|
ES2981703T3
(es)
|
2016-09-02 |
2024-10-10 |
Lentigen Tech Inc |
Composiciones y métodos para tratar cáncer con DuoCars
|
US11078483B1
(en)
|
2016-09-02 |
2021-08-03 |
KSQ Therapeutics, Inc. |
Methods for measuring and improving CRISPR reagent function
|
US11701384B2
(en)
|
2016-09-02 |
2023-07-18 |
The Regents Of The University Of California |
Methods and compositions involving interleukin-6 receptor alpha-binding single chain variable fragments
|
WO2018049025A2
(en)
|
2016-09-07 |
2018-03-15 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses
|
BR112019004662A2
(pt)
|
2016-09-12 |
2019-05-28 |
Juno Therapeutics Inc |
conjuntos de sacos de biorreator de perfusão
|
US11077178B2
(en)
|
2016-09-21 |
2021-08-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptor (CAR) that targets chemokine receptor CCR4 and its use
|
CN110225766A
(zh)
*
|
2016-09-23 |
2019-09-10 |
南加利福尼亚大学 |
嵌合抗原受体和组合物及其使用方法
|
EP3518943A4
(en)
|
2016-09-28 |
2020-04-22 |
Atossa Therapeutics, Inc. |
METHOD FOR ADAPTIVE CELL THERAPY
|
TWI719894B
(zh)
|
2016-09-28 |
2021-02-21 |
美商凱特製藥公司 |
抗原結合分子類和使用彼等之方法
|
US11072660B2
(en)
|
2016-10-03 |
2021-07-27 |
Juno Therapeutics, Inc. |
HPV-specific binding molecules
|
WO2018067991A1
(en)
|
2016-10-07 |
2018-04-12 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
MX2019003886A
(es)
|
2016-10-07 |
2019-08-05 |
Novartis Ag |
Receptores de antigenos quimericos para el tratamiento del cancer.
|
EP3445787B1
(en)
|
2016-10-07 |
2020-12-02 |
TCR2 Therapeutics Inc. |
Compositions and methods for t-cell receptors reprogramming using fusion proteins
|
CN107151654B
(zh)
*
|
2016-10-11 |
2020-05-05 |
深圳宾德生物技术有限公司 |
一种人源t淋巴细胞的培养基及其制备方法和应用
|
EP4190335A1
(en)
|
2016-10-13 |
2023-06-07 |
Juno Therapeutics, Inc. |
Immunotherapy methods and compositions involving tryptophan metabolic pathway modulators
|
CN107936120B
(zh)
*
|
2016-10-13 |
2021-03-09 |
上海赛比曼生物科技有限公司 |
Cd19靶向性的嵌合抗原受体及其制法和应用
|
JP7181862B2
(ja)
|
2016-10-18 |
2022-12-01 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
腫瘍浸潤リンパ球および治療の方法
|
WO2018075807A1
(en)
|
2016-10-19 |
2018-04-26 |
California Institute For Biomedical Research |
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
|
JP2020500010A
(ja)
|
2016-10-20 |
2020-01-09 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
分泌性バリアント免疫調節タンパク質および改変細胞療法
|
WO2018075820A2
(en)
|
2016-10-20 |
2018-04-26 |
Celgene Corporation |
Cereblon-based heterodimerizable chimeric antigen receptors
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
MX2019005029A
(es)
|
2016-11-03 |
2019-10-24 |
Juno Therapeutics Inc |
Terapia de combinación de una terapia de células t y un inhibidor de tirosina cinasa de bruton (btk).
|
WO2018093591A1
(en)
|
2016-11-03 |
2018-05-24 |
Juno Therapeutics, Inc. |
Combination therapy of a cell based therapy and a microglia inhibitor
|
AU2017355504C1
(en)
|
2016-11-04 |
2024-06-20 |
2Seventy Bio, Inc. |
Anti-BCMA CAR T cell compositions
|
US11332713B2
(en)
|
2016-11-16 |
2022-05-17 |
KSQ Therapeutics, Inc. |
Gene-regulating compositions and methods for improved immunotherapy
|
WO2018094143A1
(en)
|
2016-11-17 |
2018-05-24 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
JP2019536480A
(ja)
|
2016-11-22 |
2019-12-19 |
ナショナル ユニバーシティ オブ シンガポール |
T細胞悪性腫瘍の免疫療法のためのcd7発現およびキメラ抗原受容体の遮断
|
CN110177803A
(zh)
|
2016-11-22 |
2019-08-27 |
T细胞受体治疗公司 |
用于使用融合蛋白进行tcr重新编程的组合物和方法
|
JP2020500930A
(ja)
|
2016-11-23 |
2020-01-16 |
ノバルティス アーゲー |
エベロリムス、ダクトリシブまたは両方で免疫応答を増強する方法
|
WO2018102752A1
(en)
*
|
2016-12-02 |
2018-06-07 |
Cartesian Therapeutics, Inc. |
Cancer immuno therapy with highly enriched cd8+ chimeric antigen receptor t cells
|
ES2961666T3
(es)
|
2016-12-03 |
2024-03-13 |
Juno Therapeutics Inc |
Métodos para determinar la dosificación de células CAR-T
|
WO2018102786A1
(en)
|
2016-12-03 |
2018-06-07 |
Juno Therapeutics, Inc. |
Methods for modulation of car-t cells
|
AU2017368331A1
(en)
|
2016-12-03 |
2019-06-13 |
Acerta Pharma B.V. |
Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors
|
BR112019011207A2
(pt)
|
2016-12-05 |
2019-10-08 |
Juno Therapeutics Inc |
produção de células modificadas para terapia celular adotiva
|
CN108165568B
(zh)
*
|
2016-12-07 |
2020-12-08 |
上海恒润达生生物科技有限公司 |
一种培养CD19CAR-iNKT细胞方法及用途
|
CN107058315B
(zh)
*
|
2016-12-08 |
2019-11-08 |
上海优卡迪生物医药科技有限公司 |
敲减人PD-1的siRNA、重组表达CAR-T载体及其构建方法和应用
|
EP3551197B1
(en)
|
2016-12-12 |
2023-11-22 |
Seattle Children's Hospital (DBA Seattle Children's Research Institute) |
Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
|
CN108218994A
(zh)
*
|
2016-12-14 |
2018-06-29 |
上海恒润达生生物科技有限公司 |
一种方法培养t记忆干细胞
|
US11278570B2
(en)
|
2016-12-16 |
2022-03-22 |
B-Mogen Biotechnologies, Inc. |
Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
|
US11111483B2
(en)
|
2016-12-16 |
2021-09-07 |
B-Mogen Biotechnologies, Inc. |
Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems and methods
|
CN108276493B
(zh)
*
|
2016-12-30 |
2023-11-14 |
南京传奇生物科技有限公司 |
一种嵌合抗原受体及其应用
|
CA3048312A1
(en)
|
2017-01-01 |
2018-07-05 |
Chi-Yu Gregory Lee |
Rp215 chimeric antigen receptor construct and methods of making and using same
|
CN110248677B
(zh)
|
2017-01-05 |
2023-05-16 |
上海煦顼技术有限公司 |
人源化抗cd19抗体及其与嵌合抗原受体的用途
|
CN110121336A
(zh)
|
2017-01-05 |
2019-08-13 |
弗莱德哈钦森癌症研究中心 |
改善疫苗功效的系统和方法
|
EP3346001A1
(en)
*
|
2017-01-06 |
2018-07-11 |
TXCell |
Monospecific regulatory t cell population with cytotoxicity for b cells
|
JP2020503351A
(ja)
|
2017-01-06 |
2020-01-30 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
カリウムチャネルアゴニストによる腫瘍浸潤リンパ球の増殖及びその治療的使用
|
US10624968B2
(en)
|
2017-01-06 |
2020-04-21 |
Bicyclerd Limited |
Compounds for treating cancer
|
TW201837168A
(zh)
|
2017-01-06 |
2018-10-16 |
美商艾歐凡斯生物治療公司 |
以腫瘤壞死因子受體超家族(tnfrsf)促效劑使腫瘤浸潤淋巴球(til)擴增及til與tnfrsf促效劑的治療組合
|
CN108285920A
(zh)
*
|
2017-01-09 |
2018-07-17 |
上海恒润达生生物科技有限公司 |
一种体内检测cart细胞表达的技术及其用途
|
CA3049461A1
(en)
|
2017-01-10 |
2018-07-19 |
Juno Therapeutics, Inc. |
Epigenetic analysis of cell therapy and related methods
|
GB201700553D0
(en)
|
2017-01-12 |
2017-03-01 |
Genagon Therapeutics Ab |
Therapeutic agents
|
EP3568416A4
(en)
|
2017-01-13 |
2020-07-08 |
Celdara Medical, LLC |
TIM-1 TARGETED CHIMERIC ANTIGENIC RECEPTORS
|
MX2019008538A
(es)
|
2017-01-20 |
2019-11-05 |
Juno Therapeutics Gmbh |
Conjugados de superficie celular y composiciones y métodos celulares relacionados.
|
WO2018140391A1
(en)
|
2017-01-24 |
2018-08-02 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
CN108342363B
(zh)
*
|
2017-01-25 |
2021-02-12 |
北京马力喏生物科技有限公司 |
共表达抗msln嵌合抗原受体和免疫检查点抑制分子的转基因淋巴细胞及其用途
|
US11535662B2
(en)
|
2017-01-26 |
2022-12-27 |
Novartis Ag |
CD28 compositions and methods for chimeric antigen receptor therapy
|
RU2674894C2
(ru)
*
|
2017-01-30 |
2018-12-13 |
Общество с ограниченной ответственностью "ПЛАНТА" |
Новые люциферазы и способы их использования
|
WO2018144535A1
(en)
|
2017-01-31 |
2018-08-09 |
Novartis Ag |
Treatment of cancer using chimeric t cell receptor proteins having multiple specificities
|
WO2018144597A1
(en)
*
|
2017-01-31 |
2018-08-09 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Methods of sensitizing cancer cells to immune cell killing
|
US11649288B2
(en)
|
2017-02-07 |
2023-05-16 |
Seattle Children's Hospital |
Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
|
SI3580561T1
(sl)
|
2017-02-12 |
2024-04-30 |
Biontech Us Inc. |
Metode, osnovane na hla, in njihove sestave ter uporabe
|
AR110979A1
(es)
*
|
2017-02-14 |
2019-05-22 |
Kite Pharma Inc |
Moléculas de unión a cd70 y métodos de uso de las mismas
|
EP3582782B1
(en)
|
2017-02-17 |
2023-06-07 |
Fred Hutchinson Cancer Center |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
WO2018157072A1
(en)
|
2017-02-27 |
2018-08-30 |
Life Technologies Corporation |
Expansion of populations of t cells by the use of modified serum free media
|
US20200191774A1
(en)
|
2017-02-27 |
2020-06-18 |
Juno Therapeutics, Inc. |
Compositions, articles of manufacture and methods related to dosing in cell therapy
|
JP7178355B2
(ja)
|
2017-02-28 |
2022-11-25 |
エンドサイト・インコーポレイテッド |
Car t細胞療法のための組成物および方法
|
EP3589647A1
(en)
|
2017-02-28 |
2020-01-08 |
Novartis AG |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
US11629340B2
(en)
|
2017-03-03 |
2023-04-18 |
Obsidian Therapeutics, Inc. |
DHFR tunable protein regulation
|
CA3054939A1
(en)
|
2017-03-03 |
2018-09-07 |
Seattle Genetics, Inc. |
Glycan-interacting compounds and methods of use
|
AU2018227583B2
(en)
*
|
2017-03-03 |
2023-06-01 |
Obsidian Therapeutics, Inc. |
CD19 compositions and methods for immunotherapy
|
US20180280437A1
(en)
|
2017-03-13 |
2018-10-04 |
Kite Pharma, Inc. |
Chimeric antigen receptors for melanoma and uses thereof
|
CA3056393A1
(en)
|
2017-03-14 |
2018-09-20 |
Juno Therapeutics, Inc. |
Methods for cryogenic storage
|
EP3596115A1
(en)
|
2017-03-16 |
2020-01-22 |
Alpine Immune Sciences, Inc. |
Pd-l2 variant immunomodulatory proteins and uses thereof
|
HRP20231382T1
(hr)
|
2017-03-16 |
2024-02-16 |
Alpine Immune Sciences, Inc. |
Pd-l1 varijanta imunomodulacijskih proteina i njihova upotreba
|
SG11201907769XA
(en)
|
2017-03-16 |
2019-09-27 |
Alpine Immune Sciences Inc |
Cd80 variant immunomodulatory proteins and uses thereof
|
JP2020511136A
(ja)
|
2017-03-17 |
2020-04-16 |
フレッド ハッチンソン キャンサー リサーチ センター |
免疫調節性融合タンパク質およびその使用
|
CN110832075A
(zh)
|
2017-03-22 |
2020-02-21 |
诺华股份有限公司 |
用于免疫肿瘤学的组合物和方法
|
WO2018175676A1
(en)
|
2017-03-23 |
2018-09-27 |
The General Hospital Corporation |
Cxcr4/cxcr7 blockade and treatment of human papilloma virus-associated disease
|
JP7137896B2
(ja)
*
|
2017-03-24 |
2022-09-15 |
レンティジェン・テクノロジー・インコーポレイテッド |
抗cd33免疫療法によりがんを処置するための組成物および方法
|
CN117363636A
(zh)
|
2017-03-27 |
2024-01-09 |
新加坡国立大学 |
一种编码嵌合受体的多核苷酸
|
MX2019011570A
(es)
|
2017-03-27 |
2019-11-18 |
Nat Univ Singapore |
Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
|
WO2018183842A1
(en)
|
2017-03-31 |
2018-10-04 |
The Board Of Trustees Of The Leland Standford Junior University |
Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling
|
US11963966B2
(en)
|
2017-03-31 |
2024-04-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
WO2018183921A1
(en)
|
2017-04-01 |
2018-10-04 |
The Broad Institute, Inc. |
Methods and compositions for detecting and modulating an immunotherapy resistance gene signature in cancer
|
MX2019011679A
(es)
|
2017-04-01 |
2019-11-01 |
Avm Biotechnology Llc |
Reemplazo de un pre-acondicionamiento citotoxico antes de una inmunoterapia celular.
|
US11357796B2
(en)
|
2017-04-03 |
2022-06-14 |
Kite Pharma, Inc. |
Treatment using chimeric receptor T cells incorporating optimized polyfunctional T cells
|
AU2018250336A1
(en)
|
2017-04-07 |
2019-09-26 |
Juno Therapeutics, Inc. |
Engineered cells expressing prostate-specific membrane antigen (PSMA) or a modified form thereof and related methods
|
US20200071773A1
(en)
|
2017-04-12 |
2020-03-05 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
MX2019012189A
(es)
|
2017-04-14 |
2020-12-10 |
Juno Therapeutics Inc |
Metodos para valorar la glucosilacion de la superficie celular.
|
US11753434B2
(en)
|
2017-04-14 |
2023-09-12 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for transient gene therapy with enhanced stability
|
CN108727497A
(zh)
*
|
2017-04-17 |
2018-11-02 |
沈阳美达博生物科技有限公司 |
一种cd19抗体及其应用
|
US20200123501A1
(en)
|
2017-04-18 |
2020-04-23 |
FUJIFILM Cellular Dynamics, Inc. |
Antigen-specific immune effector cells
|
EP3612629A1
(en)
|
2017-04-18 |
2020-02-26 |
The Broad Institute, Inc. |
Compositions for detecting secretion and methods of use
|
CN110753555A
(zh)
|
2017-04-19 |
2020-02-04 |
得克萨斯州大学系统董事会 |
表达工程化抗原受体的免疫细胞
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
EP3612030A4
(en)
|
2017-04-21 |
2021-04-28 |
Ikena Oncology, Inc. |
AHR INDOLE INHIBITORS AND THEIR USES
|
JOP20180042A1
(ar)
|
2017-04-24 |
2019-01-30 |
Kite Pharma Inc |
نطاقات ربط مولد ضد متوافقة مع البشر وطرق الاستخدام
|
MA49288A
(fr)
|
2017-04-27 |
2020-03-04 |
Juno Therapeutics Gmbh |
Reactifs particulaires oligomères et leurs méthodes d'utilisation
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
EP3618842B1
(en)
|
2017-05-01 |
2023-10-18 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and an immunomodulatory compound
|
DE112018002302B4
(de)
*
|
2017-05-02 |
2020-10-22 |
Chongqing Precision Biotech Company Limited |
Chimärer Antigenrezeptor von Anti-Human-CD19-Antigen und dessen Anwendung
|
CN107226867B
(zh)
*
|
2017-07-25 |
2018-02-06 |
重庆精准生物技术有限公司 |
抗人cd19抗原的嵌合抗原受体及其应用
|
WO2018209115A1
(en)
*
|
2017-05-10 |
2018-11-15 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
US11166985B2
(en)
|
2017-05-12 |
2021-11-09 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
WO2019097305A2
(en)
|
2017-05-12 |
2019-05-23 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
EP3625261A1
(en)
|
2017-05-15 |
2020-03-25 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Bicistronic chimeric antigen receptors and their uses
|
US10415017B2
(en)
|
2017-05-17 |
2019-09-17 |
Thunder Biotech, Inc. |
Transgenic macrophages, chimeric antigen receptors, and associated methods
|
US11576933B2
(en)
|
2017-05-24 |
2023-02-14 |
Effector Therapeutics Inc. |
Compositions and methods for an improved antitumor immune response
|
EP3406733A1
(en)
|
2017-05-24 |
2018-11-28 |
SIB Swiss Institute of Bioinformatics |
Kinase mutants and uses thereof
|
JP7187486B2
(ja)
|
2017-05-25 |
2022-12-12 |
レイドス, インコーポレイテッド |
Pd-1およびctla-4二重インヒビターペプチド
|
IL270770B2
(en)
|
2017-05-26 |
2024-03-01 |
Kite Pharma Inc |
Methods of preparation and use of embryonic mesenchymal progenitor cells
|
WO2018219278A1
(en)
|
2017-06-01 |
2018-12-06 |
Innovative Cellular Therapeutics CO., LTD. |
Chimeric antigen receptor cell preparation and uses thereof
|
EP3631805A4
(en)
*
|
2017-06-02 |
2021-03-24 |
Mayo Foundation for Medical Education and Research |
SYSTEM AND METHOD FOR PROVIDING EXPERTISE FROM CLINICAL RESULTS IN DISEASE TREATMENT
|
EP3630132A1
(en)
|
2017-06-02 |
2020-04-08 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods for treatment using adoptive cell therapy
|
US11740231B2
(en)
|
2017-06-02 |
2023-08-29 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods related to toxicity associated with cell therapy
|
US11897953B2
(en)
|
2017-06-14 |
2024-02-13 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
PT3538645T
(pt)
|
2017-06-20 |
2021-04-15 |
Inst Curie |
Células imunológicas deficitárias em suv39h1
|
CA3068256A1
(en)
|
2017-06-21 |
2018-12-27 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for chimeric antigen receptor targeting cancer cells
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
BR112019027104A2
(pt)
|
2017-06-22 |
2020-08-18 |
Novartis Ag |
moléculas de anticorpo para cd73 e usos das mesmas
|
KR20200019231A
(ko)
|
2017-06-22 |
2020-02-21 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
조절 면역 세포를 제조하기 위한 방법 및 이의 용도
|
IL299348A
(en)
|
2017-06-28 |
2023-02-01 |
Regeneron Pharma |
Antigen binding proteins against human papilloma virus and methods of their use
|
CA3067602A1
(en)
|
2017-06-29 |
2019-01-03 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
JP2020530307A
(ja)
|
2017-06-30 |
2020-10-22 |
インティマ・バイオサイエンス,インコーポレーテッド |
遺伝子治療のためのアデノ随伴ウイルスベクター
|
US11235004B2
(en)
|
2017-06-30 |
2022-02-01 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Lymphocyte cell lines and uses thereof
|
CA3067914A1
(en)
|
2017-06-30 |
2019-01-03 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
MX2019015484A
(es)
|
2017-07-07 |
2020-07-28 |
H Lee Moffitt Cancer Ct & Res |
Receptores quiméricos de antígeno con dominios coestimuladores cd28 mutados.
|
CN107287164A
(zh)
*
|
2017-07-07 |
2017-10-24 |
青岛协和华美医学诊断技术有限公司 |
靶向cd19的嵌合抗原受体t细胞、制备方法及应用
|
CN107365798B
(zh)
*
|
2017-07-13 |
2020-07-14 |
山东省齐鲁细胞治疗工程技术有限公司 |
一种携带iCasp9自杀基因的CD19-CAR-T细胞及其应用
|
WO2019014581A1
(en)
|
2017-07-14 |
2019-01-17 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR MODULATING THE ACTIVITY OF A CYTOTOXIC LYMPHOCYTE
|
KR20200028447A
(ko)
*
|
2017-07-17 |
2020-03-16 |
얀센 바이오테크 인코포레이티드 |
피브로넥틴 iii형 도메인에 대한 항원 결합 영역 및 이의 사용 방법
|
BR112020001719A2
(pt)
|
2017-07-29 |
2020-07-21 |
Juno Therapeutics Inc |
reagentes para expansão de células que expressam receptores recombinantes
|
US10442867B2
(en)
|
2017-07-31 |
2019-10-15 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-CD19/CD20 immunotherapy
|
WO2019025811A1
(en)
|
2017-08-04 |
2019-02-07 |
Bicycletx Limited |
SPECIFIC BICYCLIC PEPTIDE LIGANDS OF CD137
|
EP3665308A1
(en)
|
2017-08-07 |
2020-06-17 |
The Johns Hopkins University |
Methods and materials for assessing and treating cancer
|
AU2018313950A1
(en)
|
2017-08-09 |
2020-02-13 |
Juno Therapeutics, Inc. |
Methods for producing genetically engineered cell compositions and related compositions
|
US20200239910A1
(en)
|
2017-08-09 |
2020-07-30 |
Juno Therapeutics, Inc. |
Methods and compositions for preparing genetically engineered cells
|
CN111247241A
(zh)
|
2017-08-10 |
2020-06-05 |
新加坡国立大学 |
T细胞受体缺陷型嵌合抗原受体t细胞和其使用方法
|
BR112020003116A2
(pt)
|
2017-08-17 |
2020-08-04 |
Ikena Oncology, Inc. |
inibidores de ahr e usos dos mesmos
|
EP3676403A1
(en)
|
2017-09-01 |
2020-07-08 |
Juno Therapeutics, Inc. |
Gene expression and assessment of risk of developing toxicity following cell therapy
|
JP7393328B2
(ja)
|
2017-09-01 |
2023-12-06 |
ジーピービー・サイエンティフィック・インコーポレイテッド |
マイクロ流体を使用した治療的に活性な細胞を調製する方法
|
WO2019051335A1
(en)
|
2017-09-07 |
2019-03-14 |
Juno Therapeutics, Inc. |
METHODS OF IDENTIFYING CELLULAR CHARACTERISTICS RELATED TO RESPONSES ASSOCIATED WITH CELL THERAPY
|
JP2020533986A
(ja)
|
2017-09-15 |
2020-11-26 |
ライフ テクノロジーズ コーポレーション |
細胞を培養および増殖させるための組成物および方法
|
CN107557337B
(zh)
*
|
2017-09-15 |
2020-06-26 |
山东兴瑞生物科技有限公司 |
一种抗ror1安全型嵌合抗原受体修饰的免疫细胞及其应用
|
US20200268860A1
(en)
|
2017-09-15 |
2020-08-27 |
Kite Pharma, Inc. |
Methods and systems for performing a patient-specific immunotherapy procedure with chain-of-custody and chain-of-identity biological sample tracking
|
WO2019056099A1
(en)
*
|
2017-09-19 |
2019-03-28 |
The University Of British Columbia |
ANTI-HLA-A2 ANTIBODIES AND METHODS OF USE
|
EP3684408A1
(en)
|
2017-09-19 |
2020-07-29 |
Massachusetts Institute of Technology |
Compositions for chimeric antigen receptor t cell therapy and uses thereof
|
SG11202002532XA
(en)
|
2017-09-20 |
2020-04-29 |
Univ British Columbia |
Novel anti-hla-a2 antibodies and uses thereof
|
CN109517820B
(zh)
|
2017-09-20 |
2021-09-24 |
北京宇繁生物科技有限公司 |
一种靶向HPK1的gRNA以及HPK1基因编辑方法
|
AU2018338318B2
(en)
|
2017-09-21 |
2022-12-22 |
Massachusetts Institute Of Technology |
Systems, methods, and compositions for targeted nucleic acid editing
|
US11358948B2
(en)
|
2017-09-22 |
2022-06-14 |
Kymera Therapeutics, Inc. |
CRBN ligands and uses thereof
|
WO2019060713A1
(en)
|
2017-09-22 |
2019-03-28 |
Kite Pharma, Inc. |
ANTIGEN-BINDING MOLECULES AND METHODS OF USE THEREOF
|
US20190092818A1
(en)
|
2017-09-22 |
2019-03-28 |
Kite Pharma, Inc. |
Chimeric polypeptides and uses thereof
|
EP3684365A4
(en)
|
2017-09-22 |
2021-09-08 |
Kymera Therapeutics, Inc. |
PROTEIN DEGRADATION AGENTS AND USES OF SUCH
|
EP3688143A4
(en)
*
|
2017-09-26 |
2021-09-22 |
Longwood University |
PD1 SPECIFIC CHIMERIC ANTIGEN RECEPTOR AS IMMUNOTHERAPY
|
CN109554349B
(zh)
*
|
2017-09-27 |
2022-06-24 |
亘喜生物科技(上海)有限公司 |
Pd-1基因表达沉默的工程化免疫细胞
|
TWI731268B
(zh)
*
|
2017-09-29 |
2021-06-21 |
財團法人國家衛生研究院 |
可增強抗腫瘤與抗病毒t細胞存活與其功能性之方法與組合物
|
WO2019070755A1
(en)
|
2017-10-02 |
2019-04-11 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING A GENETIC SIGNATURE OF IMMUNOTHERAPY RESISTANCE IN CANCER
|
JP2020537515A
(ja)
|
2017-10-03 |
2020-12-24 |
ジュノー セラピューティクス インコーポレイテッド |
Hpv特異的結合分子
|
EP3694875A1
(en)
|
2017-10-09 |
2020-08-19 |
Wisconsin Alumni Research Foundation |
Antibodies targeting glioblastoma stem-like cells and methods of use thereof
|
CA3077509A1
(en)
|
2017-10-10 |
2019-04-18 |
Alpine Immune Sciences, Inc. |
Ctla-4 variant immunomodulatory proteins and uses thereof
|
CN111712515A
(zh)
|
2017-10-18 |
2020-09-25 |
高山免疫科学股份有限公司 |
变体icos配体免疫调节蛋白及相关组合物和方法
|
KR20230011487A
(ko)
|
2017-10-18 |
2023-01-20 |
카이트 파마 인코포레이티드 |
키메라 항원 수용체 면역요법제를 투여하는 방법
|
US11999802B2
(en)
|
2017-10-18 |
2024-06-04 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
CN109694854B
(zh)
*
|
2017-10-20 |
2023-11-21 |
亘喜生物科技(上海)有限公司 |
通用型嵌合抗原受体t细胞制备技术
|
WO2019084055A1
(en)
|
2017-10-23 |
2019-05-02 |
Massachusetts Institute Of Technology |
CLASSIFICATION OF GENETIC VARIATION FROM UNICELLULAR TRANSCRIPTOMS
|
WO2019084234A1
(en)
*
|
2017-10-26 |
2019-05-02 |
St. Jude Childen's Research Hospital, Inc. |
METHODS AND COMPOSITIONS FOR TREATING CD33 + CANCERS AND IMPROVING IN VIVO PERSISTENCE OF CHIMERIC ANTIGEN RECEPTOR T CELLS
|
US11820823B2
(en)
|
2017-10-27 |
2023-11-21 |
Kite Pharma, Inc. |
T cell receptor antigen binding molecules and methods of use thereof
|
WO2019089798A1
(en)
|
2017-10-31 |
2019-05-09 |
Novartis Ag |
Anti-car compositions and methods
|
CN111511370A
(zh)
|
2017-11-01 |
2020-08-07 |
朱诺治疗学股份有限公司 |
对b细胞成熟抗原具有特异性的抗体和嵌合抗原受体
|
US11564946B2
(en)
|
2017-11-01 |
2023-01-31 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
CA3082010A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for b-cell maturation antigen (bcma)
|
US11851679B2
(en)
|
2017-11-01 |
2023-12-26 |
Juno Therapeutics, Inc. |
Method of assessing activity of recombinant antigen receptors
|
BR112020008340A2
(pt)
|
2017-11-01 |
2020-11-17 |
Juno Therapeutics Inc |
processo para gerar composições terapêuticas de células modificadas
|
US20210254000A1
(en)
|
2017-11-01 |
2021-08-19 |
Juno Therapeutics, Inc. |
Process for producing a t cell composition
|
US12031975B2
(en)
|
2017-11-01 |
2024-07-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
US20230061455A1
(en)
|
2017-11-01 |
2023-03-02 |
Editas Medicine, Inc. |
Methods, compositions and components for crispr-cas9 editing of tgfbr2 in t cells for immunotherapy
|
US10428141B2
(en)
*
|
2017-11-03 |
2019-10-01 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-ROR1 immunotherapy
|
SG11202003427XA
(en)
|
2017-11-06 |
2020-05-28 |
Juno Therapeutics Inc |
Combination of a cell therapy and a gamma secretase inhibitor
|
WO2019090202A1
(en)
|
2017-11-06 |
2019-05-09 |
Editas Medicine, Inc. |
Methods, compositions and components for crispr-cas9 editing of cblb in t cells for immunotherapy
|
JP7339944B2
(ja)
*
|
2017-11-07 |
2023-09-06 |
ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム |
がんの処置におけるcar-t細胞またはcar-nk細胞を用いるlilrb4のターゲティング法
|
US11802163B2
(en)
|
2017-11-10 |
2023-10-31 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptors targeting glypican-3 or mesothelin
|
WO2019094835A1
(en)
|
2017-11-10 |
2019-05-16 |
Juno Therapeutics, Inc. |
Closed-system cryogenic vessels
|
WO2019094983A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for treating cancer by targeting the clec2d-klrb1 pathway
|
WO2019099433A2
(en)
|
2017-11-14 |
2019-05-23 |
Arcellx, Inc. |
D-domain containing polypeptides and uses thereof
|
EP3710034A4
(en)
|
2017-11-14 |
2022-01-26 |
Arcellx, Inc. |
MULTIFUNCTIONAL IMMUNOCELLULAR THERAPIES
|
CA3088095A1
(en)
|
2017-11-15 |
2019-05-23 |
Novartis Ag |
Bcma-targeting chimeric antigen receptor, cd19-targeting chimeric antigen receptor, and combination therapies
|
WO2019099707A1
(en)
|
2017-11-16 |
2019-05-23 |
Kite Pharma, Inc |
Modified chimeric antigen receptors and methods of use
|
CA3083118A1
(en)
|
2017-11-22 |
2019-05-31 |
Iovance Biotherapeutics, Inc. |
Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
|
CN109837244A
(zh)
*
|
2017-11-25 |
2019-06-04 |
深圳宾德生物技术有限公司 |
一种敲除pd1的靶向cd19的嵌合抗原受体t细胞及其制备方法和应用
|
CA3083949A1
(en)
|
2017-11-30 |
2020-06-06 |
Novartis Ag |
Bcma-targeting chimeric antigen receptor, and uses thereof
|
CN111989106A
(zh)
|
2017-12-01 |
2020-11-24 |
朱诺治疗学股份有限公司 |
基因工程化细胞的给药和调节方法
|
WO2019112978A2
(en)
*
|
2017-12-04 |
2019-06-13 |
Coare Biotechnology, Inc. |
Anti-dclk1 antibodies and chimeric antigen receptors, and compositions and methods of use thereof
|
BR112020011215A2
(pt)
|
2017-12-08 |
2020-11-17 |
Juno Therapeutics Inc |
processo para a produção de uma composição de células t modificadas
|
WO2019113559A2
(en)
|
2017-12-08 |
2019-06-13 |
Juno Therapeutics, Inc. |
Phenotypic markers for cell therapy and related methods
|
MA51105A
(fr)
|
2017-12-08 |
2020-10-14 |
Juno Therapeutics Inc |
Formulation de milieux sans sérum pour la culture de cellules et ses procédés d'utilisation
|
KR20200110745A
(ko)
|
2017-12-15 |
2020-09-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
항 - cct5 결합 분자 및 이의 사용 방법
|
JP7565795B2
(ja)
|
2017-12-15 |
2024-10-11 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
腫瘍浸潤リンパ球の有益な投与を決定するシステム及び方法並びにその使用方法、並びに腫瘍浸潤リンパ球の有益な投与及びその使用方法
|
US11661439B2
(en)
|
2017-12-17 |
2023-05-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Peptide hydrogels and use thereof
|
US11793867B2
(en)
|
2017-12-18 |
2023-10-24 |
Biontech Us Inc. |
Neoantigens and uses thereof
|
CN108018312B
(zh)
*
|
2017-12-20 |
2019-09-10 |
上海优卡迪生物医药科技有限公司 |
一种t淋巴细胞白血病的car-t治疗载体及其构建方法和应用
|
EP3728282B1
(en)
|
2017-12-20 |
2023-11-22 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
AU2018392213B2
(en)
|
2017-12-20 |
2021-03-04 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein
|
GB201721833D0
(en)
*
|
2017-12-22 |
2018-02-07 |
Cancer Research Tech Ltd |
Fusion proteins
|
IL315310A
(en)
|
2017-12-26 |
2024-10-01 |
Kymera Therapeutics Inc |
IRAK joints and used in them
|
CN109971712B
(zh)
*
|
2017-12-28 |
2023-06-20 |
上海细胞治疗研究院 |
特异性靶向cd19抗原且高水平稳定表达pd-1抗体的car-t细胞及用途
|
CN109970864A
(zh)
*
|
2017-12-28 |
2019-07-05 |
上海细胞治疗研究院 |
一种双向激活共刺激分子受体及其用途
|
CN109970866B
(zh)
*
|
2017-12-28 |
2022-10-04 |
上海细胞治疗研究院 |
一种cd28双向激活共刺激分子受体及其用途
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
CN111757746A
(zh)
*
|
2018-01-05 |
2020-10-09 |
麦克赛特股份有限公司 |
癌症的长期car治疗
|
WO2019136432A1
(en)
|
2018-01-08 |
2019-07-11 |
Novartis Ag |
Immune-enhancing rnas for combination with chimeric antigen receptor therapy
|
US11919937B2
(en)
|
2018-01-09 |
2024-03-05 |
Board Of Regents, The University Of Texas System |
T cell receptors for immunotherapy
|
US10561686B2
(en)
|
2018-01-12 |
2020-02-18 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
EP3586852B8
(en)
*
|
2018-01-11 |
2021-04-28 |
Innovative Cellular Therapeutics Inc. |
Modified cell expansion and uses thereof
|
US11485743B2
(en)
|
2018-01-12 |
2022-11-01 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
WO2019140387A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
US20210023134A1
(en)
|
2018-01-15 |
2021-01-28 |
Pfizer Inc. |
Methods of administering chimeric antigen receptor immunotherapy in combination with 4-1bb agonist
|
CN112292138A
(zh)
|
2018-01-22 |
2021-01-29 |
西雅图儿童医院(Dba西雅图儿童研究所) |
Car t细胞的使用方法
|
EP3746075A4
(en)
|
2018-01-29 |
2021-09-08 |
Merck Patent GmbH |
GCN2 INHIBITORS AND THEIR USES
|
SG11202006832YA
(en)
|
2018-01-29 |
2020-08-28 |
Merck Patent Gmbh |
Gcn2 inhibitors and uses thereof
|
KR102115236B1
(ko)
*
|
2018-01-29 |
2020-05-27 |
(주)에스엠티바이오 |
췌장 또는 담관계암 치료를 위한 키메라 항원 수용체
|
EP3746569A1
(en)
|
2018-01-31 |
2020-12-09 |
Juno Therapeutics, Inc. |
Methods and reagents for assessing the presence or absence of replication competent virus
|
CN111971059A
(zh)
|
2018-01-31 |
2020-11-20 |
细胞基因公司 |
使用过继细胞疗法和检查点抑制剂的组合疗法
|
CA3090249A1
(en)
|
2018-01-31 |
2019-08-08 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
US20200390814A1
(en)
|
2018-02-02 |
2020-12-17 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Dna-chimeric antigen receptor t cells for immunotherapy
|
US20210087511A1
(en)
*
|
2018-02-09 |
2021-03-25 |
Global Life Sciences Solutions Usa Llc |
Bioprocessing methods for cell therapy
|
WO2019154313A1
(zh)
|
2018-02-11 |
2019-08-15 |
江苏恒瑞医药股份有限公司 |
一种分离的嵌合抗原受体以及包含其的修饰t细胞及用途
|
WO2019157516A1
(en)
|
2018-02-12 |
2019-08-15 |
resTORbio, Inc. |
Combination therapies
|
CN110157677A
(zh)
*
|
2018-02-12 |
2019-08-23 |
深圳宾德生物技术有限公司 |
一种靶向性t淋巴细胞及其制备方法和应用
|
US20200399383A1
(en)
|
2018-02-13 |
2020-12-24 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
AU2019222644B2
(en)
|
2018-02-13 |
2021-04-01 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
WO2019161035A1
(en)
|
2018-02-14 |
2019-08-22 |
Kite Pharma, Inc. |
Anti-idiotypic antibodies directed to the antigen-binding portion of an bcma-binding molecule
|
CA3090793A1
(en)
|
2018-02-16 |
2019-08-22 |
Kite Pharma, Inc. |
Modified pluripotent stem cells and methods of making and use
|
CA3091478A1
(en)
|
2018-02-17 |
2019-08-22 |
Flagship Pioneering Innovations V, Inc. |
Compositions and methods for membrane protein delivery
|
GB201803178D0
(en)
|
2018-02-27 |
2018-04-11 |
Univ Oslo Hf |
Specific binding molecules for htert
|
US10780120B2
(en)
|
2018-03-06 |
2020-09-22 |
The Trustees Of The University Of Pennsylvania |
Prostate-specific membrane antigen cars and methods of use thereof
|
WO2019170845A1
(en)
|
2018-03-09 |
2019-09-12 |
Ospedale San Raffaele S.R.L. |
Il-1 antagonist and toxicity induced by cell therapy
|
WO2019175328A1
(en)
|
2018-03-14 |
2019-09-19 |
Imba - Institut Für Molekulare Biotechnologie Gmbh |
Bh4pathwayactivationandusethereoffortreatingcancer
|
CN112040986A
(zh)
|
2018-03-15 |
2020-12-04 |
Ksq治疗公司 |
用于改进的免疫疗法的基因调控组合物和方法
|
US20190284553A1
(en)
|
2018-03-15 |
2019-09-19 |
KSQ Therapeutics, Inc. |
Gene-regulating compositions and methods for improved immunotherapy
|
DE102018108612A1
(de)
|
2018-03-21 |
2019-09-26 |
Immatics US, Inc. |
Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen
|
US10760075B2
(en)
|
2018-04-30 |
2020-09-01 |
Snipr Biome Aps |
Treating and preventing microbial infections
|
MA52193A
(fr)
|
2018-04-05 |
2021-02-17 |
Juno Therapeutics Inc |
Récepteurs de lymphocytes t et cellules modifiées les exprimant
|
SG11202009313VA
(en)
|
2018-04-05 |
2020-10-29 |
Juno Therapeutics Inc |
Methods of producing cells expressing a recombinant receptor and related compositions
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
2,2,─環二核苷酸
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
CN112334193A
(zh)
|
2018-04-10 |
2021-02-05 |
美国安进公司 |
Dll3的嵌合受体及其使用方法
|
KR20210007954A
(ko)
|
2018-04-12 |
2021-01-20 |
카이트 파마 인코포레이티드 |
종양 미세환경의 특징을 이용한 키메라 수용체 t 세포 치료
|
MX2020010808A
(es)
|
2018-04-13 |
2021-03-02 |
Sangamo Therapeutics France |
Receptor de antigeno quimerico especifico para el receptor de interleucina-23.
|
US20210155986A1
(en)
|
2018-04-13 |
2021-05-27 |
The Johns Hopkins University |
Non-invasive detection of response to immunotherapy
|
WO2019200250A1
(en)
|
2018-04-13 |
2019-10-17 |
Velculescu Victor E |
Non-invasive detection of response to a targeted therapy
|
AR115051A1
(es)
|
2018-04-16 |
2020-11-25 |
Univ Texas |
Enzimas quinureninasa humanas y sus usos
|
CN112292128A
(zh)
|
2018-04-16 |
2021-01-29 |
阿瑞斯医疗有限公司 |
Ep4抑制剂和其用途
|
US10869888B2
(en)
*
|
2018-04-17 |
2020-12-22 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
CN111989342B
(zh)
|
2018-04-18 |
2024-08-23 |
艾克隆株式会社 |
开关分子以及可转换嵌合抗原受体
|
KR102591947B1
(ko)
|
2018-04-19 |
2023-10-25 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
WO2019204496A1
(en)
*
|
2018-04-19 |
2019-10-24 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treating melanoma with a chimeric antigen receptor
|
CN112218865B
(zh)
|
2018-04-24 |
2024-03-12 |
沃泰克斯药物股份有限公司 |
喋啶酮化合物及其用途
|
BR112020020940A2
(pt)
|
2018-04-24 |
2021-03-02 |
Merck Patent Gmbh |
compostos antiproliferação e uso dos mesmos
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
US20210396739A1
(en)
|
2018-05-01 |
2021-12-23 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
US20210095001A1
(en)
|
2018-05-02 |
2021-04-01 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of phospholipase a2 receptor chimeric autoantibody receptor t cells
|
KR20210044736A
(ko)
|
2018-05-03 |
2021-04-23 |
주노 쎄러퓨티크스 인코퍼레이티드 |
키메라 항원 수용체(car) t세포 요법과 키나제 억제제의 조합요법
|
CN108753774B
(zh)
*
|
2018-05-03 |
2021-03-30 |
山东省齐鲁细胞治疗工程技术有限公司 |
干扰il-6表达的cd19-car-t细胞及其应用
|
TW202014193A
(zh)
|
2018-05-03 |
2020-04-16 |
捷克科學院有機化學與生物化學研究所 |
包含碳環核苷酸之2’3’-環二核苷酸
|
EP3790958A1
(en)
|
2018-05-08 |
2021-03-17 |
Life Technologies Corporation |
Compositions and methods for culturing and expanding cells
|
JP7542441B2
(ja)
|
2018-05-11 |
2024-08-30 |
クリスパー セラピューティクス アクチェンゲゼルシャフト |
癌を治療するための方法及び組成物
|
CN117304130A
(zh)
|
2018-05-14 |
2023-12-29 |
吉利德科学公司 |
Mcl-1抑制剂
|
US20210198747A1
(en)
|
2018-05-18 |
2021-07-01 |
The Johns Hopkins University |
Cell-free dna for assessing and/or treating cancer
|
WO2019226945A1
(en)
|
2018-05-23 |
2019-11-28 |
National University Of Singapore |
Blockade of cd2 surface expression and expression of chimeric antigen receptors for immunotherapy of t-cell malignancies
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
CN108715859B
(zh)
*
|
2018-05-31 |
2021-08-03 |
中国医学科学院血液病医院(中国医学科学院血液学研究所) |
靶向cd22的嵌合抗原受体及其应用
|
EP3802611A2
(en)
|
2018-06-01 |
2021-04-14 |
Novartis AG |
Binding molecules against bcma and uses thereof
|
US20210371932A1
(en)
|
2018-06-01 |
2021-12-02 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
EP4403224A3
(en)
|
2018-06-01 |
2024-07-31 |
Kite Pharma, Inc. |
Chimeric antigen receptor t cell therapy
|
MX2020013017A
(es)
*
|
2018-06-01 |
2021-03-02 |
Mayo Found Medical Education & Res |
Materiales y metodos para tratar cancer.
|
US20210123075A1
(en)
|
2018-06-08 |
2021-04-29 |
Novartis Ag |
Compositions and methods for immunooncology
|
US20220403001A1
(en)
|
2018-06-12 |
2022-12-22 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
SG11202011830SA
(en)
|
2018-06-13 |
2020-12-30 |
Novartis Ag |
Bcma chimeric antigen receptors and uses thereof
|
US12036240B2
(en)
|
2018-06-14 |
2024-07-16 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
KR20190141511A
(ko)
*
|
2018-06-14 |
2019-12-24 |
주식회사 녹십자랩셀 |
신규 펩티드, 이를 포함하는 키메라 항원 수용체 및 이를 발현하는 면역 세포
|
WO2019241758A1
(en)
|
2018-06-15 |
2019-12-19 |
Alpine Immune Sciences, Inc. |
Pd-1 variant immunomodulatory proteins and uses thereof
|
CA3104288A1
(en)
|
2018-06-21 |
2019-12-26 |
B-Mogen Biotechnologies, Inc. |
Enhanced hat family transposon-mediated gene transfer and associated compositions, systems, and methods
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
US20210155941A1
(en)
|
2018-06-22 |
2021-05-27 |
Kite Pharma Eu B.V. |
Compositions and methods for making engineered t cells
|
AU2019299439A1
(en)
|
2018-07-03 |
2021-01-21 |
Sotio, LLC |
Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof
|
EP3817748A4
(en)
|
2018-07-06 |
2022-08-24 |
Kymera Therapeutics, Inc. |
TRICYCLIC CRBN LIGANDS AND USES THEREOF
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
BR112020026746A2
(pt)
|
2018-07-13 |
2021-03-30 |
Gilead Sciences, Inc. |
Composto, composição farmacêutica, métodos para inibir pd-1, pd-l1 e/ou a interação de pd-1/pd-l1 e para tratar câncer, e, kit para tratar ou prevenir câncer ou uma doença ou condição.
|
EP3825404A4
(en)
|
2018-07-17 |
2022-04-13 |
Noile-Immune Biotech, Inc. |
CAR CONTAINING ANTI-GPC3 SINGLE STRAND ANTIBODY
|
MA53167A
(fr)
|
2018-07-18 |
2021-05-26 |
Amgen Inc |
Récepteurs chimériques de steap1 et procédés d'utilisation associées
|
EP3823665B1
(en)
|
2018-07-19 |
2024-01-24 |
Regeneron Pharmaceuticals, Inc. |
Chimeric antigen receptors with bcma specificity and uses thereof
|
CN108949759B
(zh)
*
|
2018-07-23 |
2021-06-01 |
合肥一兮生物科技有限公司 |
敲减人IL-15的siRNA、CD19 CAR表达载体、CAR-T细胞及构建方法和应用
|
CA3107383A1
(en)
|
2018-07-23 |
2020-01-30 |
Magenta Therapeutics, Inc. |
Use of anti-cd5 antibody drug conjugate (adc) in allogeneic cell therapy
|
CA3170491A1
(en)
|
2018-08-02 |
2020-02-06 |
Kite Pharma, Inc. |
Chimeric antigen receptor therapy t cell expansion kinetics and uses thereof
|
SG11202101130VA
(en)
|
2018-08-09 |
2021-03-30 |
Juno Therapeutics Inc |
Methods for assessing integrated nucleic acids
|
KR20210057730A
(ko)
|
2018-08-09 |
2021-05-21 |
주노 쎄러퓨티크스 인코퍼레이티드 |
조작 세포 및 이의 조성물 생성 방법
|
KR20210043623A
(ko)
*
|
2018-08-10 |
2021-04-21 |
주식회사 유틸렉스 |
Hla-dr에 결합하는 키메라 항원 수용체 및 car-t 세포
|
US12077785B2
(en)
|
2018-08-14 |
2024-09-03 |
Sotio Biotech Inc. |
Chimeric antigen receptor polypeptides in combination with trans metabolism molecules modulating Krebs cycle and therapeutic uses thereof
|
US20210355522A1
(en)
|
2018-08-20 |
2021-11-18 |
The Broad Institute, Inc. |
Inhibitors of rna-guided nuclease activity and uses thereof
|
WO2020068304A2
(en)
|
2018-08-20 |
2020-04-02 |
The Broad Institute, Inc. |
Inhibitors of rna-guided nuclease target binding and uses thereof
|
WO2020041387A1
(en)
|
2018-08-20 |
2020-02-27 |
The Brigham And Women's Hospital, Inc. |
Degradation domain modifications for spatio-temporal control of rna-guided nucleases
|
CN110856724B
(zh)
*
|
2018-08-24 |
2022-05-27 |
杭州康万达医药科技有限公司 |
包含核酸及car修饰的免疫细胞的治疗剂及其应用
|
BR112021003830A2
(pt)
|
2018-08-28 |
2021-07-20 |
Fred Hutchinson Cancer Research Center |
métodos e composições para terapia celular t adotiva incorporando sinalização notch induzida
|
WO2020047164A1
(en)
|
2018-08-28 |
2020-03-05 |
Vor Biopharma, Inc |
Genetically engineered hematopoietic stem cells and uses thereof
|
US20220348682A1
(en)
|
2018-08-30 |
2022-11-03 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Chimeric antigen receptor cells for treating solid tumor
|
WO2020047306A1
(en)
|
2018-08-30 |
2020-03-05 |
Innovative Cellular Therapeutics CO., LTD. |
Chimeric antigen receptor cells for treating solid tumor
|
US20210171909A1
(en)
|
2018-08-31 |
2021-06-10 |
Novartis Ag |
Methods of making chimeric antigen receptor?expressing cells
|
US10548889B1
(en)
|
2018-08-31 |
2020-02-04 |
X4 Pharmaceuticals, Inc. |
Compositions of CXCR4 inhibitors and methods of preparation and use
|
US11866494B2
(en)
*
|
2018-08-31 |
2024-01-09 |
Innovative Cellular Therapeutics Holdings, Ltd. |
CAR T therapy through uses of co-stimulation
|
CN112639083A
(zh)
|
2018-08-31 |
2021-04-09 |
诺华股份有限公司 |
制备表达嵌合抗原受体的细胞的方法
|
JP2022500499A
(ja)
|
2018-09-07 |
2022-01-04 |
ピク セラピューティクス, インコーポレイテッド |
Eif4e阻害剤およびその使用
|
US20220050114A1
(en)
|
2018-09-11 |
2022-02-17 |
Juno Therapeutics, Inc. |
Methods for mass spectrometry analysis of engineered cell compositions
|
JP2022501361A
(ja)
|
2018-09-19 |
2022-01-06 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
バリアントcd80融合タンパク質および関連構築物の方法および使用
|
WO2020068764A1
(en)
|
2018-09-24 |
2020-04-02 |
The Medical College Of Wisconsin, Inc. |
Anti-cd30 antibodies and methods of use
|
US20220047633A1
(en)
|
2018-09-28 |
2022-02-17 |
Novartis Ag |
Cd22 chimeric antigen receptor (car) therapies
|
EP3856763A1
(en)
|
2018-09-28 |
2021-08-04 |
Massachusetts Institute of Technology |
Collagen-localized immunomodulatory molecules and methods thereof
|
WO2020069409A1
(en)
|
2018-09-28 |
2020-04-02 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
CA3115139A1
(en)
|
2018-10-01 |
2020-04-09 |
Adicet Bio Inc. |
Compositions and methods regarding engineered and non-engineered .gamma..delta.-t cells for treatment of hematological tumors
|
WO2020072700A1
(en)
|
2018-10-02 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
US11179397B2
(en)
|
2018-10-03 |
2021-11-23 |
Gilead Sciences, Inc. |
Imidazopyrimidine derivatives
|
EP3488851A1
(en)
|
2018-10-03 |
2019-05-29 |
AVM Biotechnology, LLC |
Immunoablative therapies
|
US11851663B2
(en)
|
2018-10-14 |
2023-12-26 |
Snipr Biome Aps |
Single-vector type I vectors
|
US20210379057A1
(en)
|
2018-10-16 |
2021-12-09 |
Massachusetts Institute Of Technology |
Nutlin-3a for use in treating a mycobacterium tuberculosis infection
|
MX2021004588A
(es)
|
2018-10-22 |
2022-01-18 |
Shanghai Genbase Biotechnology Co Ltd |
Anticuerpo anti-cldn18.2 y sus usos.
|
KR20210093908A
(ko)
|
2018-10-23 |
2021-07-28 |
리제너론 파아마슈티컬스, 인크. |
Ny-eso-1 t 세포 수용체 및 이의 사용 방법
|
WO2020086742A1
(en)
|
2018-10-24 |
2020-04-30 |
Obsidian Therapeutics, Inc. |
Er tunable protein regulation
|
KR102635333B1
(ko)
|
2018-10-24 |
2024-02-15 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
EP3870146A4
(en)
*
|
2018-10-25 |
2022-08-10 |
Innovative Cellular Therapeutics Holdings, Ltd. |
INCREASE OR MAINTAIN T-CELL SUBPULATIONS IN ADOPTIVE T-CELL THERAPY
|
US20220170097A1
(en)
|
2018-10-29 |
2022-06-02 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
WO2020092057A1
(en)
|
2018-10-30 |
2020-05-07 |
Yale University |
Compositions and methods for rapid and modular generation of chimeric antigen receptor t cells
|
AU2019370705A1
(en)
|
2018-10-31 |
2021-05-27 |
Juno Therapeutics Gmbh |
Methods for selection and stimulation of cells and apparatus for same
|
MX2021005047A
(es)
|
2018-10-31 |
2021-09-08 |
Gilead Sciences Inc |
Compuestos de 6-azabenzimidazol sustituidos como inhibidores de hpk1.
|
TW202136261A
(zh)
|
2018-10-31 |
2021-10-01 |
美商基利科學股份有限公司 |
經取代之6-氮雜苯并咪唑化合物
|
AU2019372331A1
(en)
|
2018-11-01 |
2021-05-27 |
Juno Therapeutics, Inc. |
Methods for treatment using chimeric antigen receptors specific for B-cell maturation antigen
|
WO2020097132A1
(en)
|
2018-11-06 |
2020-05-14 |
Juno Therapeutics, Inc. |
Process for producing genetically engineered t cells
|
CN109503717A
(zh)
*
|
2018-11-07 |
2019-03-22 |
南京卡提医学科技有限公司 |
嵌合抗原受体DAP12-T2A-CD8α-CD19scfv-NKp44及其用途
|
US20220054545A1
(en)
*
|
2018-11-07 |
2022-02-24 |
Sotio, LLC |
ANTI-GPC3 CHIMERIC ANTIGEN RECEPTORS (CARs) IN COMBINATION WITH TRANS CO-STIMULATORY MOLECULES AND THERAPEUTIC USES THEREOF
|
CN109467604A
(zh)
*
|
2018-11-07 |
2019-03-15 |
南京卡提医学科技有限公司 |
嵌合抗原受体DAP12-T2A-CD8α-CD19scFv-TREM1及其用途
|
US20220008477A1
(en)
|
2018-11-08 |
2022-01-13 |
Juno Therapeutics, Inc. |
Methods and combinations for treatment and t cell modulation
|
EP3880180A2
(en)
|
2018-11-14 |
2021-09-22 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for t cell delivery
|
MX2021005734A
(es)
|
2018-11-16 |
2021-09-10 |
Juno Therapeutics Inc |
Metodos de dosificacion de celulas t modificadas para el tratamiento de malignidades de celulas b.
|
WO2020106621A1
(en)
|
2018-11-19 |
2020-05-28 |
Board Of Regents, The University Of Texas System |
A modular, polycistronic vector for car and tcr transduction
|
US10918667B2
(en)
|
2018-11-20 |
2021-02-16 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expressing therapeutic agent and uses thereof
|
BR112021010297A2
(pt)
|
2018-11-28 |
2021-08-24 |
Board Of Regents, The University Of Texas System |
Edição de genomas multiplexadores de células imunes para aumentar a funcionalidade e resistência ao ambiente supressivo
|
US20220033778A1
(en)
|
2018-11-29 |
2022-02-03 |
Board Of Regents, The University Of Texas System |
Methods for ex vivo expansion of natural killer cells and use thereof
|
JP2022516401A
(ja)
|
2018-11-30 |
2022-02-28 |
カイメラ セラピューティクス, インコーポレイテッド |
Irak分解剤およびそれらの使用
|
CN113710256A
(zh)
|
2018-11-30 |
2021-11-26 |
朱诺治疗学股份有限公司 |
使用过继细胞疗法的治疗方法
|
FI3886894T3
(fi)
|
2018-11-30 |
2024-05-24 |
Juno Therapeutics Inc |
Menetelmiä annosteluun ja b-solumaligniteettien hoitoon adoptiivisessa soluterapiassa
|
EP4198057A1
(en)
|
2018-12-05 |
2023-06-21 |
F. Hoffmann-La Roche AG |
Diagnostic methods and compositions for cancer immunotherapy
|
AU2019393243A1
(en)
*
|
2018-12-07 |
2021-07-01 |
Gracell Biotechnologies (Shanghai) Co., Ltd. |
Compositions and methods for immunotherapy
|
FI3894549T3
(fi)
|
2018-12-10 |
2024-10-23 |
Amgen Inc |
Mutatoitu piggybac-transposaasi
|
US20220056092A1
(en)
|
2018-12-11 |
2022-02-24 |
Obsidian Therapeutics, Inc. |
Membrane bound il12 compositions and methods for tunable regulation
|
EP3893899A2
(en)
|
2018-12-12 |
2021-10-20 |
Kite Pharma, Inc. |
Chimeric antigen receptors and car-t cells and methods of use
|
WO2020131586A2
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
EP3670530A1
(en)
|
2018-12-18 |
2020-06-24 |
Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft |
Cd22-specific t cell receptors and adoptive t cell therapy for treatment of b cell malignancies
|
CN113271945A
(zh)
|
2018-12-20 |
2021-08-17 |
诺华股份有限公司 |
包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案和药物组合
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
CN113474840A
(zh)
|
2018-12-21 |
2021-10-01 |
百欧恩泰美国公司 |
用于预测hla ii类特异性表位及表征cd4+ t细胞的方法和系统
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
CN113382741A
(zh)
*
|
2019-01-06 |
2021-09-10 |
艾宾妥斯生物公司 |
Car t细胞方法和构建体
|
WO2020160050A1
(en)
|
2019-01-29 |
2020-08-06 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1)
|
CN117264064A
(zh)
|
2019-02-04 |
2023-12-22 |
米纳瓦生物技术公司 |
抗nme抗体及治疗癌症或癌症转移的方法
|
JP2022520106A
(ja)
|
2019-02-15 |
2022-03-28 |
ユニバーシティ オブ サザン カリフォルニア |
Lym-1およびlym-2抗体組成物ならびに改善されたcar構築物
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
WO2020165833A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
CA3126087A1
(en)
|
2019-02-25 |
2020-09-03 |
Novartis Ag |
Mesoporous silica particles compositions for viral delivery
|
CN113543799B
(zh)
|
2019-03-01 |
2024-08-02 |
艾洛基治疗公司 |
靶向dll3的嵌合抗原受体和结合剂
|
WO2020180733A1
(en)
*
|
2019-03-01 |
2020-09-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
WO2020180882A1
(en)
|
2019-03-05 |
2020-09-10 |
Nkarta, Inc. |
Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
JP7350871B2
(ja)
|
2019-03-07 |
2023-09-26 |
インスティチュート オブ オーガニック ケミストリー アンド バイオケミストリー エーエスシーアール,ヴイ.ヴイ.アイ. |
2’3’-環状ジヌクレオチドおよびそのプロドラッグ
|
CA3129011C
(en)
|
2019-03-07 |
2023-12-19 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotides and prodrugs thereof
|
US11766447B2
(en)
|
2019-03-07 |
2023-09-26 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3′3′-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
BR112021017744A2
(pt)
|
2019-03-08 |
2021-11-16 |
Obsidian Therapeutics Inc |
Composições e métodos de cd40l para regulação ajustável
|
CA3128971A1
(en)
|
2019-03-08 |
2020-09-17 |
Klinikum Der Universitat Munchen |
Ccr8 expressing lymphocytes for targeted tumor therapy
|
WO2020186101A1
(en)
|
2019-03-12 |
2020-09-17 |
The Broad Institute, Inc. |
Detection means, compositions and methods for modulating synovial sarcoma cells
|
US20220142948A1
(en)
|
2019-03-18 |
2022-05-12 |
The Broad Institute, Inc. |
Compositions and methods for modulating metabolic regulators of t cell pathogenicity
|
MX2021011320A
(es)
|
2019-03-19 |
2021-12-10 |
Fundacio Privada Inst Dinvestigacio Oncològica De Vall Hebron |
Terapia de combinacion con omomyc y un anticuerpo que se une a pd-1 o a ctla-4 para el tratamiento del cancer.
|
EP3942025A1
(en)
|
2019-03-21 |
2022-01-26 |
Novartis AG |
Car-t cell therapies with enhanced efficacy
|
CA3135569A1
(en)
|
2019-04-02 |
2020-10-08 |
Bicycletx Limited |
Bicycle toxin conjugates and uses thereof
|
SG11202110829YA
(en)
|
2019-04-05 |
2021-10-28 |
Kymera Therapeutics Inc |
Stat degraders and uses thereof
|
US20220168389A1
(en)
|
2019-04-12 |
2022-06-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
TWI751517B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
TW202210480A
(zh)
|
2019-04-17 |
2022-03-16 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
WO2020219742A1
(en)
|
2019-04-24 |
2020-10-29 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
DK3959235T5
(da)
|
2019-04-26 |
2024-08-05 |
Allogene Therapeutics Inc |
Rituximab-resistente kimære antigenreceptorer og anvendelser deraf
|
MX2021013005A
(es)
|
2019-04-26 |
2021-12-10 |
Allogene Therapeutics Inc |
Metodos de fabricacion de celulas car-t alogenicas.
|
EA202192975A1
(ru)
|
2019-04-30 |
2022-02-01 |
Криспр Терапьютикс Аг |
Аллогенная клеточная терапия b-клеточных злокачественных новообразований с применением генетически сконструированных т-клеток, нацеливающихся на cd19
|
KR20220016083A
(ko)
|
2019-04-30 |
2022-02-08 |
센티 바이오사이언시스, 인코포레이티드 |
키메라 수용체 및 이의 사용 방법
|
BR112021021200A2
(pt)
|
2019-05-01 |
2021-12-21 |
Juno Therapeutics Inc |
Células expressando um receptor quimérico de um locus cd247 modificado, polinucleotídeos relacionados e métodos
|
JP2022531222A
(ja)
|
2019-05-01 |
2022-07-06 |
ジュノー セラピューティクス インコーポレイテッド |
改変されたtgfbr2遺伝子座から組換え受容体を発現する細胞、関連ポリヌクレオチド、および方法
|
EP4249075A3
(en)
|
2019-05-03 |
2023-11-08 |
Kite Pharma, Inc. |
Methods of administering chimeric antigen receptor immunotherapy
|
CN113784732B
(zh)
|
2019-05-07 |
2024-03-22 |
亘喜生物科技(上海)有限公司 |
靶向bcma的工程化免疫细胞及其用途
|
US20220235340A1
(en)
|
2019-05-20 |
2022-07-28 |
The Broad Institute, Inc. |
Novel crispr-cas systems and uses thereof
|
AU2020279371A1
(en)
|
2019-05-22 |
2021-12-23 |
Leidos, Inc. |
LAG 3 binding peptides
|
WO2020237025A1
(en)
|
2019-05-23 |
2020-11-26 |
Gilead Sciences, Inc. |
Substituted exo-methylene-oxindoles which are hpk1/map4k1 inhibitors
|
US20220251538A1
(en)
|
2019-05-23 |
2022-08-11 |
Matjaz Vogelsang |
Method for removal of nucleic acids impurities from liquid composition comprising genetically engineered particles or proteins
|
WO2020243371A1
(en)
|
2019-05-28 |
2020-12-03 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
US11458149B1
(en)
|
2019-05-31 |
2022-10-04 |
Ikena Oncology, Inc. |
TEAD inhibitors and uses thereof
|
JPWO2020246563A1
(zh)
*
|
2019-06-05 |
2020-12-10 |
|
|
EP3980530A1
(en)
|
2019-06-07 |
2022-04-13 |
Juno Therapeutics, Inc. |
Automated t cell culture
|
WO2020252405A1
(en)
|
2019-06-12 |
2020-12-17 |
Obsidian Therapeutics, Inc. |
Ca2 compositions and methods for tunable regulation
|
JP2022537700A
(ja)
|
2019-06-12 |
2022-08-29 |
ジュノー セラピューティクス インコーポレイテッド |
細胞媒介細胞傷害性療法と生存促進性bcl2ファミリータンパク質の阻害剤との併用療法
|
EP3983537A1
(en)
|
2019-06-12 |
2022-04-20 |
Obsidian Therapeutics, Inc. |
Ca2 compositions and methods for tunable regulation
|
BR112021025735A2
(pt)
|
2019-06-21 |
2022-03-08 |
Kite Pharma Inc |
Receptores de tgf-ss e métodos de uso
|
EP3986427A1
(en)
|
2019-06-24 |
2022-04-27 |
Childrens Hospital Los Angeles |
Bcl11b overexpression to enhance human thymopoiesis and t cell function
|
KR20220032568A
(ko)
|
2019-06-25 |
2022-03-15 |
길리애드 사이언시즈, 인코포레이티드 |
Flt3l-fc 융합 단백질 및 사용 방법
|
JP2022538974A
(ja)
|
2019-06-26 |
2022-09-07 |
マサチューセッツ インスチテュート オブ テクノロジー |
免疫調節融合タンパク質-金属水酸化物錯体およびその方法
|
KR20220031054A
(ko)
|
2019-07-02 |
2022-03-11 |
더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 |
Egfrviii에 결합하는 단일클론 항체 및 이의 용도
|
CA3138188A1
(en)
|
2019-07-02 |
2021-01-07 |
Fred Hutchinson Cancer Research Center |
Recombinant ad35 vectors and related gene therapy improvements
|
GB201909573D0
(en)
|
2019-07-03 |
2019-08-14 |
Cancer Research Tech Ltd |
Modulation of T cell cytotoxicity and related therapy
|
JPWO2021010326A1
(zh)
|
2019-07-12 |
2021-01-21 |
|
|
WO2021011907A1
(en)
|
2019-07-18 |
2021-01-21 |
Gpb Scientific, Inc. |
Ordered processing of blood products to produce therapeutically active cells
|
US20220251572A1
(en)
|
2019-07-23 |
2022-08-11 |
Mnemo Therapeutics |
Immune cells defective for suv39h1
|
US20220281994A1
(en)
|
2019-07-24 |
2022-09-08 |
Regeneron Pharmaceuticals, Inc. |
Chimeric Antigen Receptors with MAGE-A4 Specificity and Uses Thereof
|
CN110305849B
(zh)
*
|
2019-08-01 |
2021-03-30 |
广东万海细胞生物科技有限公司 |
稳定表达car的t细胞及其制备方法与应用
|
GB201911066D0
(en)
|
2019-08-02 |
2019-09-18 |
Achilles Therapeutics Ltd |
T cell therapy
|
EP4010377A4
(en)
*
|
2019-08-09 |
2023-09-06 |
A2 Biotherapeutics, Inc. |
CELL SURFACE RECEPTORS THAT RESPOND TO LOSS OF HETEROZYGOSIS
|
US20220282333A1
(en)
|
2019-08-13 |
2022-09-08 |
The General Hospital Corporation |
Methods for predicting outcomes of checkpoint inhibition and treatment thereof
|
WO2021035194A1
(en)
|
2019-08-22 |
2021-02-25 |
Juno Therapeutics, Inc. |
Combination therapy of a t cell therapy and an enhancer of zeste homolog 2 (ezh2) inhibitor and related methods
|
WO2021040736A1
(en)
|
2019-08-30 |
2021-03-04 |
Obsidian Therapeutics, Inc. |
Tandem cd19 car-based compositions and methods for immunotherapy
|
US20220298501A1
(en)
|
2019-08-30 |
2022-09-22 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
CN114600172A
(zh)
|
2019-08-30 |
2022-06-07 |
朱诺治疗学股份有限公司 |
用于将细胞分类的机器学习方法
|
WO2021043804A1
(en)
|
2019-09-02 |
2021-03-11 |
Institut Curie |
Immunotherapy targeting tumor neoantigenic peptides
|
WO2021046143A1
(en)
|
2019-09-03 |
2021-03-11 |
Sana Biotechnology, Inc. |
Cd24-associated particles and related methods and uses thereof
|
CA3147441A1
(en)
|
2019-09-03 |
2021-03-11 |
Allogene Therapeutics, Inc. |
Methods of preparing t cells for t cell therapy
|
WO2021046451A1
(en)
|
2019-09-06 |
2021-03-11 |
Obsidian Therapeutics, Inc. |
Compositions and methods for dhfr tunable protein regulation
|
WO2021050601A1
(en)
|
2019-09-09 |
2021-03-18 |
Scribe Therapeutics Inc. |
Compositions and methods for use in immunotherapy
|
US11058725B2
(en)
|
2019-09-10 |
2021-07-13 |
Obsidian Therapeutics, Inc. |
CA2 compositions and methods for tunable regulation
|
WO2021051088A1
(en)
*
|
2019-09-13 |
2021-03-18 |
Ohio State Innovation Foundation |
Nk cell immunotherapy compositions, methods of making and methods of using same
|
WO2021050964A1
(en)
|
2019-09-13 |
2021-03-18 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
WO2021053559A1
(en)
|
2019-09-18 |
2021-03-25 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
US20230127263A1
(en)
*
|
2019-09-20 |
2023-04-27 |
The University Of North Carolina At Chapel Hill |
Modified t cells and methods of preparing the same
|
EP4032907A4
(en)
|
2019-09-20 |
2023-07-05 |
Shanghai Genbase Biotechnology Co., Ltd. |
BCMA-TARGETING CHEMERA ANTIGENIC ANTIBODIES AND RECEPTOR
|
WO2021061648A1
(en)
|
2019-09-23 |
2021-04-01 |
Massachusetts Institute Of Technology |
Methods and compositions for stimulation of endogenous t cell responses
|
KR102287180B1
(ko)
*
|
2019-10-01 |
2021-08-09 |
충북대학교 산학협력단 |
Cd138에 특이적으로 결합하는 키메릭 항원 수용체, 이를 발현하는 면역세포 및 이의 항암 용도
|
CA3153197A1
(en)
|
2019-10-03 |
2021-04-08 |
Ryan T. Gill |
Crispr systems with engineered dual guide nucleic acids
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
US11793787B2
(en)
|
2019-10-07 |
2023-10-24 |
The Broad Institute, Inc. |
Methods and compositions for enhancing anti-tumor immunity by targeting steroidogenesis
|
CN118178645A
(zh)
|
2019-10-18 |
2024-06-14 |
四十七公司 |
用于治疗骨髓增生异常综合征和急性髓系白血病的联合疗法
|
EP4048304A1
(en)
|
2019-10-22 |
2022-08-31 |
Institut Curie |
Immunotherapy targeting tumor neoantigenic peptides
|
CN110679588A
(zh)
*
|
2019-10-23 |
2020-01-14 |
厦门生命互联科技有限公司 |
一种嵌合抗原受体t细胞冻存介质及用途
|
WO2021081330A1
(en)
|
2019-10-23 |
2021-04-29 |
Kite Pharma, Inc. |
Anti-idiotypic antigen binding molecules and methods of use thereof
|
TWI717880B
(zh)
|
2019-10-24 |
2021-02-01 |
中國醫藥大學附設醫院 |
Hla-g特異性嵌合抗原受體、核酸、hla-g特異性嵌合抗原受體表達質體、表達hla-g特異性嵌合抗原受體細胞、其用途以及用於治療癌症之醫藥組合物
|
CA3159380A1
(en)
|
2019-10-30 |
2021-05-06 |
Juno Therapeutics Gmbh |
Cell selection and/or stimulation devices and methods of use
|
US11844800B2
(en)
|
2019-10-30 |
2023-12-19 |
Massachusetts Institute Of Technology |
Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia
|
MX2022005123A
(es)
|
2019-10-31 |
2022-05-30 |
Forty Seven Inc |
Tratamiento basado en anti-cd47 y anti-cd20 para cancer hematologico.
|
US20220403002A1
(en)
|
2019-11-01 |
2022-12-22 |
Kyoto Prefectural Public University Corporation |
B-cell antibody receptor and use thereof
|
AU2020379043A1
(en)
|
2019-11-07 |
2022-06-02 |
Juno Therapeutics, Inc. |
Combination of a T cell therapy and (S)-3-[4-(4-morpholin-4-ylmethyl-benzyloxy)-1-oxo-1,3-dihydro-isoindol-2-yl]-piperidine-2,6-dione
|
TWI778443B
(zh)
|
2019-11-12 |
2022-09-21 |
美商基利科學股份有限公司 |
Mcl1抑制劑
|
CA3157613A1
(en)
|
2019-11-20 |
2021-05-27 |
Gi Cell, Inc. |
Medium composition for culturing t cells and method for culturing t cells using same
|
WO2021108528A1
(en)
|
2019-11-26 |
2021-06-03 |
Ikena Oncology, Inc. |
Polymorphic carbazole derivatives and uses thereof
|
AR120566A1
(es)
|
2019-11-26 |
2022-02-23 |
Novartis Ag |
Receptores de antígeno quiméricos y sus usos
|
US11975026B2
(en)
|
2019-11-26 |
2024-05-07 |
Novartis Ag |
CD19 and CD22 chimeric antigen receptors and uses thereof
|
AU2020395318A1
(en)
|
2019-12-06 |
2022-06-09 |
Juno Therapeutics, Inc. |
Methods related to toxicity and response associated with cell therapy for treating B cell malignancies
|
EP4069742A1
(en)
|
2019-12-06 |
2022-10-12 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to gprc5d-targeted binding domains and related compositions and methods
|
US20230028050A1
(en)
|
2019-12-06 |
2023-01-26 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to bcma-targeted binding domains and related compositions and methods
|
MX2022007576A
(es)
|
2019-12-17 |
2022-09-23 |
Kymera Therapeutics Inc |
Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos.
|
EP4076524A4
(en)
|
2019-12-17 |
2023-11-29 |
Kymera Therapeutics, Inc. |
IRAQ DEGRADERS AND USES THEREOF
|
TW202135858A
(zh)
|
2019-12-20 |
2021-10-01 |
瑞士商諾華公司 |
抗TGFβ抗體和檢查點抑制劑用於治療增殖性疾病之用途
|
AU2020412780A1
(en)
|
2019-12-23 |
2022-07-21 |
Kymera Therapeutics, Inc. |
SMARCA degraders and uses thereof
|
DK4081305T3
(da)
|
2019-12-24 |
2024-10-14 |
Carna Biosciences Inc |
Diacylglycerinkinase modulerende forbindelser
|
JP7088902B2
(ja)
*
|
2019-12-27 |
2022-06-21 |
クレージュ メディカル カンパニー,リミテッド |
キメラ抗原受容体タンパク質をコードする核酸およびキメラ抗原受容体タンパク質を発現するtリンパ球
|
EP4081344A1
(en)
|
2019-12-28 |
2022-11-02 |
GPB Scientific, Inc. |
Microfluidic cartridges for processing particles and cells
|
CN113150167A
(zh)
*
|
2020-01-22 |
2021-07-23 |
中国人民解放军总医院第五医学中心 |
一种能够反转pd-1免疫抑制信号的car t细胞结构em1设计
|
JP2023511408A
(ja)
|
2020-01-23 |
2023-03-17 |
ザ チルドレンズ メディカル センター コーポレーション |
ヒト多能性幹細胞からのストロマフリーt細胞分化法
|
MX2022009137A
(es)
|
2020-01-24 |
2022-10-21 |
Regeneron Pharma |
Antígeno expresado preferentemente en receptores de linfocitos t de melanoma (prame) y sus métodos de uso.
|
KR20220145341A
(ko)
|
2020-01-24 |
2022-10-28 |
주노 쎄러퓨티크스 인코퍼레이티드 |
입양 세포 요법에서 여포성 림프종 및 변연부 림프종의 투여 및 치료 방법
|
AU2021214142A1
(en)
|
2020-01-28 |
2022-09-08 |
Juno Therapeutics, Inc. |
Methods for T cell transduction
|
WO2021155897A1
(en)
|
2020-02-03 |
2021-08-12 |
MVZ Prof. Niendorf Pathologie Hamburg-West GmbH |
Marker set for the diagnosis and treatment of cancer
|
CN115361955A
(zh)
|
2020-02-12 |
2022-11-18 |
朱诺治疗学股份有限公司 |
针对bcma的嵌合抗原受体t细胞组合物及其方法和用途
|
BR112022015236A2
(pt)
|
2020-02-12 |
2022-09-20 |
Juno Therapeutics Inc |
Composições de células t do receptor de antígeno quimérico direcionado a cd19 e métodos e usos das mesmas
|
PE20231067A1
(es)
|
2020-02-14 |
2023-07-17 |
Jounce Therapeutics Inc |
Anticuerpos y proteinas de fusion que se unen a ccr8 y usos de estos
|
WO2021167908A1
(en)
|
2020-02-17 |
2021-08-26 |
Board Of Regents, The University Of Texas System |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
US12076343B2
(en)
|
2020-02-19 |
2024-09-03 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Engineered safety in cell therapy
|
CA3173737A1
(en)
|
2020-02-27 |
2021-09-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
BR112022017148A2
(pt)
|
2020-02-27 |
2022-11-08 |
Novartis Ag |
Métodos para produzir células que expressam receptor de antígeno quimérico
|
CN111269326A
(zh)
*
|
2020-02-28 |
2020-06-12 |
南京北恒生物科技有限公司 |
新型嵌合抗原受体及其用途
|
AR121506A1
(es)
|
2020-03-03 |
2022-06-08 |
Pic Therapeutics Inc |
Inhibidores del eif4e y sus usos
|
AU2021357520A1
(en)
|
2020-03-05 |
2022-09-29 |
Neotx Therapeutics Ltd. |
Methods and compositions for treating cancer with immune cells
|
AU2021236145A1
(en)
|
2020-03-10 |
2022-09-22 |
Dana-Farber Cancer Institute, Inc. |
Methods for generating engineered memory-like NK cells and compositions thereof
|
EP4118112A1
(en)
|
2020-03-10 |
2023-01-18 |
Massachusetts Institute of Technology |
Compositions and methods for immunotherapy of npm1c-positive cancer
|
CN113402612A
(zh)
|
2020-03-17 |
2021-09-17 |
西比曼生物科技(香港)有限公司 |
靶向cd19和cd20的联合嵌合抗原受体及其应用
|
BR112022018678A2
(pt)
|
2020-03-19 |
2022-11-01 |
Kymera Therapeutics Inc |
Degradadores de mdm2 e usos dos mesmos
|
MX2022012191A
(es)
|
2020-03-31 |
2023-01-05 |
Sana Biotechnology Inc |
Partículas lipídicas dirigidas y composiciones y usos de estas.
|
EP3892720A1
(en)
|
2020-04-06 |
2021-10-13 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Presenting cell and use thereof in cell therapy
|
BR112022020333A2
(pt)
|
2020-04-10 |
2022-11-22 |
Juno Therapeutics Inc |
Métodos e usos relacionados à terapia celular projetada com um receptor de antígeno quimérico que alveja o antígeno de maturação de células b
|
US20230340040A1
(en)
*
|
2020-04-14 |
2023-10-26 |
St. Jude Children's Research Hospital, Inc. |
Chimeric myd88 receptors
|
US20210324331A1
(en)
*
|
2020-04-15 |
2021-10-21 |
Amgen Inc. |
Process for generating genetically engineered autologous t cells
|
GB202005599D0
(en)
|
2020-04-17 |
2020-06-03 |
Univ London |
Modulation of t cell cytotoxicity and related therapy
|
MX2022013530A
(es)
|
2020-04-28 |
2023-02-01 |
Juno Therapeutics Inc |
Combinación de terapia de células t dirigida a bcma y un compuesto inmunomodulador.
|
CA3176654A1
(en)
|
2020-04-28 |
2021-11-04 |
Karl PEGGS |
T cell therapy
|
GB202006254D0
(en)
|
2020-04-28 |
2020-06-10 |
Institute Of Cancer Res |
Anti-cancer vaccines and related therapy
|
WO2021221782A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
US20210340524A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
BR112022020769A2
(pt)
|
2020-05-01 |
2022-12-20 |
Gilead Sciences Inc |
Compostos de 2,4-dioxopirimidina de inibição de cd73
|
MX2022013898A
(es)
|
2020-05-05 |
2023-02-09 |
Regeneron Pharma |
Car que comprende cd28 zeta y cd3 zeta.
|
WO2021228999A1
(en)
|
2020-05-12 |
2021-11-18 |
Institut Curie |
Neoantigenic epitopes associated with sf3b1 mutations
|
CN115803824A
(zh)
|
2020-05-13 |
2023-03-14 |
朱诺治疗学股份有限公司 |
鉴定与临床反应相关的特征的方法及其用途
|
EP4150057A2
(en)
|
2020-05-13 |
2023-03-22 |
Juno Therapeutics, Inc. |
Process for producing donor-batched cells expressing a recombinant receptor
|
US20230190780A1
(en)
*
|
2020-05-15 |
2023-06-22 |
Precision Biosciences, Inc. |
Methods for immunotherapy
|
EP4153301A2
(en)
|
2020-05-21 |
2023-03-29 |
Board of Regents, The University of Texas System |
T cell receptors with vgll1 specificity and uses thereof
|
WO2021240240A1
(en)
|
2020-05-27 |
2021-12-02 |
Antion Biosciences Sa |
Adapter molecules to re-direct car t cells to an antigen of interest
|
US12043654B2
(en)
|
2020-06-02 |
2024-07-23 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Anti-GCC antibody and CAR thereof for treating digestive system cancer
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
MX2022015062A
(es)
|
2020-06-04 |
2023-04-10 |
Carisma Therapeutics Inc |
Nuevas construcciones para receptores de antígenos quiméricos.
|
WO2021244654A1
(en)
*
|
2020-06-05 |
2021-12-09 |
Nanjing Legend Biotech Co., Ltd. |
Activation induced cytokine production in immune cells
|
IL298780A
(en)
|
2020-06-08 |
2023-02-01 |
Minerva Biotechnologies Corp |
Anti-NME antibody and method for treating cancer or cancer metastases
|
CA3186600A1
(en)
|
2020-06-08 |
2021-12-16 |
Janssen Biotech, Inc. |
Cell-based assay for determining the in vitro tumor killing activity of chimeric antigen expressing immune cells
|
KR20230024967A
(ko)
|
2020-06-11 |
2023-02-21 |
노파르티스 아게 |
Zbtb32 억제제 및 이의 용도
|
JP2023531676A
(ja)
|
2020-06-23 |
2023-07-25 |
ノバルティス アーゲー |
3-(1-オキソイソインドリン-2-イル)ピぺリジン-2,6-ジオン誘導体を含む投与レジメン
|
WO2021260675A1
(en)
|
2020-06-24 |
2021-12-30 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
US20240216508A1
(en)
|
2020-06-26 |
2024-07-04 |
Juno Therapeutics Gmbh |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
AU2021308078A1
(en)
|
2020-07-17 |
2023-02-09 |
Children's Hospital Los Angeles |
Chimeric MyD88 receptors for redirecting immunosuppressive signaling and related compositions and methods
|
KR102297396B1
(ko)
|
2020-07-29 |
2021-09-06 |
(주)티카로스 |
면역시냅스를 안정화시키는 키메라 항원 수용체(car) t 세포
|
CA3190266A1
(en)
|
2020-07-30 |
2022-02-03 |
Institut Curie |
Immune cells defective for socs1
|
CA3189692A1
(en)
|
2020-07-31 |
2022-02-03 |
Leidos, Inc. |
Lag3 binding peptides
|
CN116134027A
(zh)
|
2020-08-03 |
2023-05-16 |
诺华股份有限公司 |
杂芳基取代的3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
KR20230095918A
(ko)
|
2020-08-05 |
2023-06-29 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Ror1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법
|
KR20230074718A
(ko)
|
2020-08-13 |
2023-05-31 |
사나 바이오테크놀로지, 인크. |
저면역원성 세포로 감작된 환자를 치료하는 방법 및 관련 방법 및 조성물
|
AU2021325947A1
(en)
|
2020-08-13 |
2023-03-02 |
Yale University |
Compositions and methods for engineering and selection of CAR T cells with desired phenotypes
|
KR20230084470A
(ko)
|
2020-08-14 |
2023-06-13 |
카이트 파마 인코포레이티드 |
면역 세포 기능의 향상
|
US20240240255A1
(en)
|
2020-08-17 |
2024-07-18 |
Bicycletx Limited |
Bicycle conjugates specific for nectin-4 and uses thereof
|
KR20230052291A
(ko)
|
2020-08-20 |
2023-04-19 |
에이투 바이오쎄라퓨틱스, 인크. |
Ceacam 양성 암을 치료하기 위한 조성물 및 방법
|
MX2023002041A
(es)
|
2020-08-20 |
2023-04-27 |
A2 Biotherapeutics Inc |
Composiciones y métodos para tratar cánceres positivos para mesotelina.
|
KR20230058427A
(ko)
|
2020-08-21 |
2023-05-03 |
노파르티스 아게 |
Car 발현 세포의 생체내 생성을 위한 조성물 및 방법
|
WO2022046760A2
(en)
|
2020-08-25 |
2022-03-03 |
Kite Pharma, Inc. |
T cells with improved functionality
|
US20230302135A1
(en)
*
|
2020-08-26 |
2023-09-28 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Hybrid allosteric receptor-engineered stem cells
|
EP4225444A1
(en)
|
2020-10-12 |
2023-08-16 |
Leidos, Inc. |
Immunomodulatory peptides
|
CN116600816A
(zh)
*
|
2020-10-16 |
2023-08-15 |
尼昂克技术公司 |
用于治疗cns感染的poh和瑞德西韦的组合
|
US12024559B2
(en)
|
2020-10-23 |
2024-07-02 |
Asher Biotherapeutics, Inc. |
Fusions with CD8 antigen binding molecules for modulating immune cell function
|
US20220155299A1
(en)
|
2020-10-28 |
2022-05-19 |
Kite Pharma, Inc. |
Flow cytometric method for characterization of t-cell impurities
|
KR20230104222A
(ko)
|
2020-11-06 |
2023-07-07 |
노파르티스 아게 |
B 세포 악성종양 치료를 위한 항-cd19 작용제 및 b 세포 표적화제 병용 요법
|
AU2021378316A1
(en)
|
2020-11-13 |
2023-06-01 |
Novartis Ag |
Combination therapies with chimeric antigen receptor (car)-expressing cells
|
US20230051406A1
(en)
|
2020-11-13 |
2023-02-16 |
Catamaran Bio, Inc. |
Genetically modified natural killer cells and methods of use thereof
|
CN112195250A
(zh)
*
|
2020-11-20 |
2021-01-08 |
山东省医学科学院附属医院 |
一种qPCR试剂盒及应用
|
IL302744A
(en)
|
2020-11-24 |
2023-07-01 |
Lyell Immunopharma Inc |
Methods for production, total preparations and methods of using regenerated T cells
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
WO2022133030A1
(en)
|
2020-12-16 |
2022-06-23 |
Juno Therapeutics, Inc. |
Combination therapy of a cell therapy and a bcl2 inhibitor
|
AR124414A1
(es)
|
2020-12-18 |
2023-03-22 |
Century Therapeutics Inc |
Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
|
CA3205830A1
(en)
|
2020-12-24 |
2022-06-30 |
Kite Pharma, Inc. |
Prostate cancer chimeric antigen receptors
|
TW202242117A
(zh)
|
2020-12-30 |
2022-11-01 |
美商亞勞諾斯醫療公司 |
包含多順反子表現卡匣之重組載體及其使用方法
|
IL303473A
(en)
|
2020-12-31 |
2023-08-01 |
Sana Biotechnology Inc |
Methods and compositions for modulating CAR-T activity
|
CA3207182A1
(en)
|
2021-01-10 |
2022-07-14 |
Kite Pharma, Inc. |
T cell therapy
|
US20240325554A1
(en)
|
2021-01-11 |
2024-10-03 |
Bicycle TX Limited |
Methods for treating cancer
|
MX2023008081A
(es)
|
2021-01-11 |
2023-09-12 |
Sana Biotechnology Inc |
Uso de vectores virales dirigidos a cd8.
|
IL304031A
(en)
|
2021-01-14 |
2023-08-01 |
Inst Curie |
Variants of single-domain HER2 antibodies and their chimeric antigenic receptors
|
UY39610A
(es)
|
2021-01-20 |
2022-08-31 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
CN117062611A
(zh)
|
2021-01-26 |
2023-11-14 |
惠和生物技术(上海)有限公司 |
嵌合抗原受体(car)构建体和表达car构建体的nk细胞
|
CA3209218A1
(en)
*
|
2021-01-27 |
2022-08-04 |
H. Lee Moffitt Cancer Center And Research Institute Inc. |
Bi-specific car t cells for b cell malignancies
|
IL303847A
(en)
|
2021-01-28 |
2023-08-01 |
Allogene Therapeutics Inc |
Methods for transferring immune cells
|
EP4284512A1
(en)
|
2021-01-28 |
2023-12-06 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for treating cytokine release syndrome
|
WO2022167445A1
(en)
|
2021-02-02 |
2022-08-11 |
Liminal Biosciences Limited |
Gpr84 antagonists and uses thereof
|
IL304905A
(en)
|
2021-02-15 |
2023-10-01 |
Kymera Therapeutics Inc |
IRAK4 joints and their uses
|
EP4294950A1
(en)
|
2021-02-20 |
2023-12-27 |
Kite Pharma, Inc. |
Gene markers for selecting immunotherapies
|
KR20230165771A
(ko)
|
2021-03-03 |
2023-12-05 |
주노 쎄러퓨티크스 인코퍼레이티드 |
T 세포 요법 및 dgk 억제제의 조합
|
CA3212530A1
(en)
|
2021-03-05 |
2022-09-09 |
Shanghai GenBase Biotechnology Co., Ltd. |
Anti-cldn6 antibody and use thereof
|
EP4301756A1
(en)
|
2021-03-05 |
2024-01-10 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
WO2022192439A1
(en)
|
2021-03-11 |
2022-09-15 |
Kite Pharma, Inc. |
Improving immune cell function
|
EP4304635A1
(en)
|
2021-03-11 |
2024-01-17 |
Mnemo Therapeutics |
Tumor neoantigenic peptides and uses thereof
|
CA3212964A1
(en)
|
2021-03-11 |
2022-09-15 |
Mnemo Therapeutics |
Tumor neoantigenic peptides
|
IL305804A
(en)
|
2021-03-11 |
2023-11-01 |
Inst Curie |
Transmembrane neoantigenic peptides
|
EP4310188A1
(en)
|
2021-03-17 |
2024-01-24 |
Daiichi Sankyo Company, Limited |
Gene coding for chimeric receptor for anti-acetylcholine receptor autoantibody
|
EP4314280A1
(en)
|
2021-03-22 |
2024-02-07 |
Juno Therapeutics, Inc. |
Method to assess potency of viral vector particles
|
CN117321417A
(zh)
|
2021-03-22 |
2023-12-29 |
朱诺治疗学股份有限公司 |
确定治疗性细胞组合物的效力的方法
|
WO2022213062A1
(en)
|
2021-03-29 |
2022-10-06 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
WO2022212400A1
(en)
|
2021-03-29 |
2022-10-06 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
BR112023020012A2
(pt)
|
2021-03-29 |
2023-11-14 |
Juno Therapeutics Inc |
Combinação de uma terapia de células t que expressam car e um composto imunomodulador para o tratamento de linfoma
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
EP4320435A1
(en)
|
2021-04-09 |
2024-02-14 |
Achilles Therapeutics UK Limited |
Batch release assay for pharmaceutical products relating to t cell therapies
|
GB202109886D0
(en)
|
2021-07-08 |
2021-08-25 |
Achilles Therapeutics Uk Ltd |
Assay
|
TW202302145A
(zh)
|
2021-04-14 |
2023-01-16 |
美商基利科學股份有限公司 |
CD47/SIRPα結合及NEDD8活化酶E1調節次單元之共抑制以用於治療癌症
|
US20220336087A1
(en)
|
2021-04-16 |
2022-10-20 |
Kite Pharma, Inc. |
Methods and systems for scheduling a patient-specific immunotherapy procedure
|
WO2022221726A2
(en)
|
2021-04-16 |
2022-10-20 |
Juno Therapeutics, Inc. |
Combination therapies with bcma-directed t cell therapy
|
KR20230172002A
(ko)
|
2021-04-16 |
2023-12-21 |
카이트 파마 인코포레이티드 |
Taci/bcma 이중 결합 분자
|
AU2022257093A1
(en)
|
2021-04-16 |
2023-11-02 |
Celgene Corporation |
T cell therapy in patients who have had prior stem cell transplant
|
CA3215081A1
(en)
|
2021-04-16 |
2022-10-20 |
Alfredo C. Castro |
Mek inhibitors and uses thereof
|
EP4326286A2
(en)
*
|
2021-04-23 |
2024-02-28 |
Myeloid Therapeutics, Inc. |
Compositions and methods for conditioning patients for cell therapy
|
EP4330377A2
(en)
|
2021-04-27 |
2024-03-06 |
Takeda Pharmaceutical Company Limited |
Recombinant antigen presenting cells
|
WO2022229853A1
(en)
|
2021-04-27 |
2022-11-03 |
Novartis Ag |
Viral vector production system
|
IL308231A
(en)
|
2021-05-04 |
2024-01-01 |
Regeneron Pharma |
MAGE-44-specific chimeric antigen receptors and their uses
|
WO2022234009A2
(en)
|
2021-05-06 |
2022-11-10 |
Juno Therapeutics Gmbh |
Methods for stimulating and transducing t cells
|
KR20240020735A
(ko)
|
2021-05-07 |
2024-02-15 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Cdk2 분해제 및 그 용도
|
EP4337227A2
(en)
|
2021-05-14 |
2024-03-20 |
Kite Pharma, Inc. |
Chimeric antigen receptor t cell therapy
|
WO2022245671A1
(en)
|
2021-05-18 |
2022-11-24 |
Gilead Sciences, Inc. |
Methods of using flt3l-fc fusion proteins
|
MX2023013684A
(es)
|
2021-05-19 |
2024-03-13 |
Sana Biotechnology Inc |
Células t primarias negativas rhesus d (rhd) hipoinmunógenas.
|
CA3221231A1
(en)
|
2021-05-24 |
2022-12-01 |
Kite Pharma, Inc. |
Chimeric antigen receptor
|
BR112023024501A2
(pt)
*
|
2021-05-26 |
2024-02-15 |
Univ Emory |
Método de tratamento da síndrome de down, método de melhora de eficácia de uma vacina e método de tratamento de câncer
|
KR20240013135A
(ko)
|
2021-05-27 |
2024-01-30 |
사나 바이오테크놀로지, 인크. |
조작된 hla-e 또는 hla-g를 포함하는 저면역원성 세포
|
IL308836A
(en)
|
2021-05-28 |
2024-01-01 |
Sana Biotechnology Inc |
Lipid Particles Containing Baboon Truncated Endogenous Retrovirus (BAEV) Envelope Glycoprotein and Related Methods and Uses
|
WO2022256448A2
(en)
|
2021-06-01 |
2022-12-08 |
Artisan Development Labs, Inc. |
Compositions and methods for targeting, editing, or modifying genes
|
KR20240049794A
(ko)
|
2021-06-07 |
2024-04-17 |
프로비던스 헬스 앤드 서비시즈 - 오레곤 |
Cxcr5, pd-1, 및 icos 발현 종양 반응성 cd4 t 세포 및 그의 용도
|
CN117730100A
(zh)
|
2021-06-08 |
2024-03-19 |
凯德药业股份有限公司 |
Gpc3结合分子
|
EP4370676A2
(en)
|
2021-06-18 |
2024-05-22 |
Artisan Development Labs, Inc. |
Compositions and methods for targeting, editing or modifying human genes
|
AU2022299605A1
(en)
|
2021-06-22 |
2024-01-04 |
Achilles Therapeutics Uk Limited |
A method for producing antigen-specific t cells
|
CA3222595A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
IL309378A
(en)
|
2021-06-23 |
2024-02-01 |
Gilead Sciences Inc |
DIACYLGLYERCOL KINASE MODULATING COMPOUNDS
|
CA3222277A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
WO2022271659A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
KR20240026507A
(ko)
|
2021-06-29 |
2024-02-28 |
플래그쉽 파이어니어링 이노베이션스 브이, 인크. |
타노트랜스미션을 촉진시키도록 엔지니어링된 면역 세포 및 이의 용도
|
WO2023278811A1
(en)
|
2021-07-01 |
2023-01-05 |
Indapta Therapeutics, Inc. |
Engineered natural killer (nk) cells and related methods
|
US20230027004A1
(en)
|
2021-07-01 |
2023-01-26 |
Kite Pharma, Inc. |
Closed-system and method for autologous and allogeneic cell therapy manufacturing
|
US20230103457A1
(en)
|
2021-07-02 |
2023-04-06 |
Kite Pharma, Inc. |
Method for identifying variants in gene products from gene constructs used in cell therapy applications
|
US20240368145A1
(en)
|
2021-07-09 |
2024-11-07 |
Immunic Ag |
Methods for treating cancer
|
WO2023287827A2
(en)
|
2021-07-14 |
2023-01-19 |
Sana Biotechnology, Inc. |
Altered expression of y chromosome-linked antigens in hypoimmunogenic cells
|
JP2024525789A
(ja)
*
|
2021-07-16 |
2024-07-12 |
サナ バイオテクノロジー,インコーポレイテッド |
細胞ベースの療法のためのポリシストロニックベクター
|
US20240325534A1
(en)
*
|
2021-07-19 |
2024-10-03 |
The Trustees Of The University Of Pennsylvania |
Chimeric antigen receptor (car)-t signaling optimization for tuning antigen activation threshold
|
US20230190799A1
(en)
*
|
2021-07-21 |
2023-06-22 |
City Of Hope |
Chimeric antigen receptor t cells targeting cea and anti-cea-il2 immunocytokines for cancer therapy
|
WO2023010114A1
(en)
|
2021-07-30 |
2023-02-02 |
Kite Pharma, Inc. |
Monitoring and management of cell therapy-induced toxicities
|
CA3228262A1
(en)
|
2021-08-04 |
2023-02-09 |
The Regents Of The University Of Colorado, A Body Corporate |
Lat activating chimeric antigen receptor t cells and methods of use thereof
|
EP4381081A1
(en)
|
2021-08-04 |
2024-06-12 |
Sana Biotechnology, Inc. |
Use of cd4-targeted viral vectors
|
WO2023019128A1
(en)
*
|
2021-08-09 |
2023-02-16 |
The Trustees Of The University Of Pennyslvania |
Optimizing t cell differentiation state with micrornas
|
EP4384193A2
(en)
|
2021-08-11 |
2024-06-19 |
Sana Biotechnology, Inc. |
Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions
|
JP2024534772A
(ja)
|
2021-08-11 |
2024-09-26 |
サナ バイオテクノロジー,インコーポレイテッド |
同種異系細胞療法用の遺伝子改変細胞
|
WO2023019227A1
(en)
|
2021-08-11 |
2023-02-16 |
Sana Biotechnology, Inc. |
Genetically modified cells for allogeneic cell therapy to reduce complement-mediated inflammatory reactions
|
TW202321435A
(zh)
|
2021-08-11 |
2023-06-01 |
美商薩那生物科技公司 |
用於改變低免疫原性細胞中之基因表現之可誘導系統
|
EP4384189A1
(en)
|
2021-08-11 |
2024-06-19 |
Sana Biotechnology, Inc. |
Genetically modified primary cells for allogeneic cell therapy
|
EP4387991A1
(en)
|
2021-08-18 |
2024-06-26 |
Julius-Maximilians-Universität Würzburg |
Hybrid tumor/cancer therapy based on targeting the resolution of or inducing transcription-replication conflicts (trcs)
|
JP2024531364A
(ja)
|
2021-08-20 |
2024-08-29 |
ノバルティス アーゲー |
キメラ抗原受容体発現細胞を作製する方法
|
MX2024002436A
(es)
|
2021-08-24 |
2024-06-03 |
Ecole Polytechnique Fed Lausanne Epfl |
Celulas que expresan il-10 para inmunoterapias mejoradas contra el cancer.
|
JP2024534127A
(ja)
|
2021-08-25 |
2024-09-18 |
ピク セラピューティクス, インコーポレイテッド |
eIF4E阻害剤及びその使用
|
EP4392421A1
(en)
|
2021-08-25 |
2024-07-03 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
WO2023049933A1
(en)
|
2021-09-27 |
2023-03-30 |
Sotio Biotech Inc. |
Chimeric receptor polypeptides in combination with trans metabolism molecules that re-direct glucose metabolites out of the glycolysis pathway and therapeutic uses thereof
|
CR20240195A
(es)
|
2021-10-14 |
2024-06-20 |
Arsenal Biosciences Inc |
Células inmunitarias que tienen arnhc coexpresados y sistemas de compuerta lógica
|
US20230303655A1
(en)
|
2021-10-18 |
2023-09-28 |
Kite Pharma, Inc. |
Signaling domains for chimeric antigen receptors
|
EP4423078A1
(en)
|
2021-10-28 |
2024-09-04 |
Gilead Sciences, Inc. |
Pyridizin-3(2h)-one derivatives
|
MX2024005066A
(es)
|
2021-10-29 |
2024-05-24 |
Gilead Sciences Inc |
Compuestos de cd73.
|
KR20240112994A
(ko)
|
2021-11-03 |
2024-07-19 |
셀진 코포레이션 |
골수종을 치료하는 데 사용하기 위한 b-세포 성숙 항원에 특이적인 키메라 항원 수용체
|
WO2023081715A1
(en)
|
2021-11-03 |
2023-05-11 |
Viracta Therapeutics, Inc. |
Combination of car t-cell therapy with btk inhibitors and methods of use thereof
|
WO2023091909A1
(en)
|
2021-11-16 |
2023-05-25 |
Sotio Biotech Inc. |
Treatment of myxoid/round cell liposarcoma patients
|
WO2023092119A2
(en)
|
2021-11-22 |
2023-05-25 |
Ludwig Institute For Cancer Research Ltd |
Methods for predicting responsiveness to a cancer therapy
|
WO2023105000A1
(en)
|
2021-12-09 |
2023-06-15 |
Zygosity Limited |
Vector
|
WO2023115039A2
(en)
|
2021-12-17 |
2023-06-22 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae fusion glycoproteins
|
WO2023115041A1
(en)
|
2021-12-17 |
2023-06-22 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae attachment glycoproteins
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
CN118488948A
(zh)
|
2021-12-22 |
2024-08-13 |
吉利德科学公司 |
Ikaros锌指家族降解剂及其用途
|
CN118488946A
(zh)
|
2021-12-22 |
2024-08-13 |
吉利德科学公司 |
Ikaros锌指家族降解剂及其用途
|
IL313704A
(en)
|
2021-12-23 |
2024-08-01 |
Sana Biotechnology Inc |
Chimeric antigen T (CAR) cells for the treatment of autoimmune diseases and related methods
|
EP4456910A1
(en)
|
2021-12-28 |
2024-11-06 |
Mnemo Therapeutics |
Immune cells with inactivated suv39h1 and modified tcr
|
WO2023129929A1
(en)
|
2021-12-30 |
2023-07-06 |
Tr1X, Inc. |
Cd4+ t cells expressing il-10 and chimeric antigen receptors and uses thereof
|
WO2023133595A2
(en)
|
2022-01-10 |
2023-07-13 |
Sana Biotechnology, Inc. |
Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
|
WO2023137472A2
(en)
|
2022-01-14 |
2023-07-20 |
Tune Therapeutics, Inc. |
Compositions, systems, and methods for programming t cell phenotypes through targeted gene repression
|
WO2023137471A1
(en)
|
2022-01-14 |
2023-07-20 |
Tune Therapeutics, Inc. |
Compositions, systems, and methods for programming t cell phenotypes through targeted gene activation
|
US20230227779A1
(en)
|
2022-01-19 |
2023-07-20 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Enhanced Chimeric Antigen Receptor Cells in Hypoxic Tumor Microenvironment
|
AU2023209589A1
(en)
|
2022-01-21 |
2024-08-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Modulation of suv39h1 expression by rnas
|
TW202340168A
(zh)
|
2022-01-28 |
2023-10-16 |
美商基利科學股份有限公司 |
Parp7抑制劑
|
KR20240137075A
(ko)
|
2022-01-28 |
2024-09-19 |
주노 쎄러퓨티크스 인코퍼레이티드 |
세포 조성물의 제조 방법
|
IL314437A
(en)
|
2022-01-31 |
2024-09-01 |
Kymera Therapeutics Inc |
IRAK joints and their uses
|
WO2023150181A1
(en)
|
2022-02-01 |
2023-08-10 |
President And Fellows Of Harvard College |
Methods and compositions for treating cancer
|
WO2023150518A1
(en)
|
2022-02-01 |
2023-08-10 |
Sana Biotechnology, Inc. |
Cd3-targeted lentiviral vectors and uses thereof
|
WO2023150647A1
(en)
|
2022-02-02 |
2023-08-10 |
Sana Biotechnology, Inc. |
Methods of repeat dosing and administration of lipid particles or viral vectors and related systems and uses
|
WO2023154890A2
(en)
*
|
2022-02-11 |
2023-08-17 |
Fred Hutchinson Cancer Center |
Chimeric antigen receptors binding steap1
|
WO2023154578A1
(en)
|
2022-02-14 |
2023-08-17 |
Sana Biotechnology, Inc. |
Methods of treating patients exhibiting a prior failed therapy with hypoimmunogenic cells
|
KR20240144434A
(ko)
|
2022-02-15 |
2024-10-02 |
카이트 파마 인코포레이티드 |
면역요법으로 인한 유해사례 예측
|
IL315000A
(en)
|
2022-02-17 |
2024-10-01 |
Sana Biotechnology Inc |
Transgenic CD47 proteins and their uses
|
AU2023223404A1
(en)
|
2022-02-22 |
2024-08-29 |
Juno Therapeutics, Inc. |
Proteinase 3 (pr3) chimeric autoantibody receptor t cells and related methods and uses
|
TW202340457A
(zh)
|
2022-02-28 |
2023-10-16 |
美商凱特製藥公司 |
同種異體治療細胞
|
WO2023167882A1
(en)
|
2022-03-01 |
2023-09-07 |
Artisan Development Labs, Inc. |
Composition and methods for transgene insertion
|
WO2023172883A1
(en)
|
2022-03-07 |
2023-09-14 |
Alpine Immune Sciences, Inc. |
Immunomodulatory proteins of variant cd80 polypeptides, cell therapies thereof and related methods and uses
|
WO2023170606A1
(en)
|
2022-03-08 |
2023-09-14 |
Alentis Therapeutics Ag |
Use of anti-claudin-1 antibodies to increase t cell availability
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2023173137A1
(en)
|
2022-03-11 |
2023-09-14 |
Yale University |
Compositions and methods for efficient and stable genetic modification of eukaryotic cells
|
WO2023173123A1
(en)
|
2022-03-11 |
2023-09-14 |
Sana Biotechnology, Inc. |
Genetically modified cells and compositions and uses thereof
|
EP4245756B1
(en)
|
2022-03-17 |
2024-10-09 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
WO2023178348A1
(en)
|
2022-03-18 |
2023-09-21 |
The Regents Of The University Of Colorado, A Body Corporate |
Genetically engineered t-cell co-receptors and methods of use thereof
|
WO2023180552A1
(en)
|
2022-03-24 |
2023-09-28 |
Institut Curie |
Immunotherapy targeting tumor transposable element derived neoantigenic peptides in glioblastoma
|
WO2023183817A1
(en)
|
2022-03-24 |
2023-09-28 |
Gilead Sciences, Inc. |
Combination therapy for treating trop-2 expressing cancers
|
GB202204386D0
(en)
|
2022-03-28 |
2022-05-11 |
Cambridge Entpr Ltd |
Engineered immune cell platform
|
WO2023193015A1
(en)
|
2022-04-01 |
2023-10-05 |
Sana Biotechnology, Inc. |
Cytokine receptor agonist and viral vector combination therapies
|
TW202345901A
(zh)
|
2022-04-05 |
2023-12-01 |
美商基利科學股份有限公司 |
用於治療結腸直腸癌之組合療法
|
WO2023196921A1
(en)
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of Colorado, A Body Corporate |
Granzyme expressing t cells and methods of use
|
WO2023196933A1
(en)
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of Colorado, A Body Corporate |
Chimeric antigen receptor t cells and methods of use thereof
|
US20230374036A1
(en)
|
2022-04-21 |
2023-11-23 |
Gilead Sciences, Inc. |
Kras g12d modulating compounds
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
WO2023211972A1
(en)
|
2022-04-28 |
2023-11-02 |
Medical University Of South Carolina |
Chimeric antigen receptor modified regulatory t cells for treating cancer
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
WO2023213969A1
(en)
|
2022-05-05 |
2023-11-09 |
Juno Therapeutics Gmbh |
Viral-binding protein and related reagents, articles, and methods of use
|
WO2023220644A1
(en)
|
2022-05-10 |
2023-11-16 |
Yale University |
Compositions and methods of synthetic ctla-4 tails for reprogramming of car-t cells and enhancement of anti-tumor efficacy
|
WO2023220655A1
(en)
|
2022-05-11 |
2023-11-16 |
Celgene Corporation |
Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
|
WO2023220641A2
(en)
|
2022-05-11 |
2023-11-16 |
Juno Therapeutics, Inc. |
Methods and uses related to t cell therapy and production of same
|
EP4279085A1
(en)
|
2022-05-20 |
2023-11-22 |
Mnemo Therapeutics |
Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease
|
WO2023230581A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Methods of manufacturing t cell therapies
|
US11878958B2
(en)
|
2022-05-25 |
2024-01-23 |
Ikena Oncology, Inc. |
MEK inhibitors and uses thereof
|
WO2023230548A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Method for predicting response to a t cell therapy
|
WO2023230272A1
(en)
|
2022-05-27 |
2023-11-30 |
Kite Pharma, Inc. |
Non-viral delivery of cell therapy constructs
|
US20230392119A1
(en)
|
2022-05-27 |
2023-12-07 |
Kite Pharma, Inc. |
Compositions and methods for preparing engineered lymphocytes for cell therapy
|
WO2023240143A1
(en)
|
2022-06-09 |
2023-12-14 |
Kite Pharma, Inc. |
Methods of preparing lymphocytes for cell therapy cross reference to related applications
|
WO2023239940A1
(en)
|
2022-06-10 |
2023-12-14 |
Research Development Foundation |
Engineered fcriib selective igg1 fc variants and uses thereof
|
WO2023242343A1
(en)
|
2022-06-15 |
2023-12-21 |
Immunoscape Pte. Ltd. |
Human t cell receptors specific for antigenic peptides derived from mitogen-activated protein kinase 8 interacting protein 2 (mapk8ip2), epstein-barr virus or human endogenous retrovirus, and uses thereof
|
WO2023250400A1
(en)
|
2022-06-22 |
2023-12-28 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
GB202209518D0
(en)
|
2022-06-29 |
2022-08-10 |
Snipr Biome Aps |
Treating & preventing E coli infections
|
WO2024006960A1
(en)
|
2022-06-29 |
2024-01-04 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids
|
WO2024007020A1
(en)
|
2022-06-30 |
2024-01-04 |
Indapta Therapeutics, Inc. |
Combination of engineered natural killer (nk) cells and antibody therapy and related methods
|
US20240116928A1
(en)
|
2022-07-01 |
2024-04-11 |
Gilead Sciences, Inc. |
Cd73 compounds
|
WO2024026377A1
(en)
|
2022-07-27 |
2024-02-01 |
Sana Biotechnology, Inc. |
Methods of transduction using a viral vector and inhibitors of antiviral restriction factors
|
WO2024026107A2
(en)
|
2022-07-28 |
2024-02-01 |
Lentigen Technology, Inc. |
Chimeric antigen receptor therapies for treating solid tumors
|
TW202416950A
(zh)
|
2022-08-02 |
2024-05-01 |
英商利米那生物科技有限公司 |
雜芳基甲醯胺及相關gpr84拮抗劑及其用途
|
TW202416972A
(zh)
|
2022-08-02 |
2024-05-01 |
英商利米那生物科技有限公司 |
經取代之吡啶酮gpr84拮抗劑及其用途
|
WO2024030441A1
(en)
|
2022-08-02 |
2024-02-08 |
National University Corporation Hokkaido University |
Methods of improving cellular therapy with organelle complexes
|
TW202415650A
(zh)
|
2022-08-02 |
2024-04-16 |
英商利米那生物科技有限公司 |
芳基-三唑基及相關gpr84拮抗劑及其用途
|
TW202417617A
(zh)
|
2022-08-10 |
2024-05-01 |
日商武田藥品工業股份有限公司 |
低免疫原性之經修飾細胞
|
WO2024040208A1
(en)
|
2022-08-19 |
2024-02-22 |
Sotio Biotech Inc. |
Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof
|
WO2024040207A1
(en)
|
2022-08-19 |
2024-02-22 |
Sotio Biotech Inc. |
Genetically engineered natural killer (nk) cells with chimeric receptor polypeptides in combination with trans metabolism molecules and therapeutic uses thereof
|
WO2024044779A2
(en)
|
2022-08-26 |
2024-02-29 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for delta-like ligand 3 (dll3)
|
WO2024044670A1
(en)
|
2022-08-26 |
2024-02-29 |
Kite Pharma, Inc. |
Improving immune cell function
|
WO2024054944A1
(en)
|
2022-09-08 |
2024-03-14 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and continuous or intermittent dgk inhibitor dosing
|
WO2024056809A1
(en)
|
2022-09-15 |
2024-03-21 |
Novartis Ag |
Treatment of autoimmune disorders using chimeric antigen receptor therapy
|
WO2024064642A2
(en)
|
2022-09-19 |
2024-03-28 |
Tune Therapeutics, Inc. |
Compositions, systems, and methods for modulating t cell function
|
WO2024064824A2
(en)
|
2022-09-21 |
2024-03-28 |
Yale University |
Compositions and methods for identification of membrane targets for enhancement of nk cell therapy
|
WO2024064668A1
(en)
|
2022-09-21 |
2024-03-28 |
Gilead Sciences, Inc. |
FOCAL IONIZING RADIATION AND CD47/SIRPα DISRUPTION ANTICANCER COMBINATION THERAPY
|
WO2024062138A1
(en)
|
2022-09-23 |
2024-03-28 |
Mnemo Therapeutics |
Immune cells comprising a modified suv39h1 gene
|
WO2024073583A1
(en)
|
2022-09-30 |
2024-04-04 |
Caribou Biosciences, Inc. |
Anti-ror1 chimeric antigen receptors (cars), car-nk cells and related methods
|
WO2024077256A1
(en)
|
2022-10-07 |
2024-04-11 |
The General Hospital Corporation |
Methods and compositions for high-throughput discovery ofpeptide-mhc targeting binding proteins
|
WO2024081820A1
(en)
|
2022-10-13 |
2024-04-18 |
Sana Biotechnology, Inc. |
Viral particles targeting hematopoietic stem cells
|
WO2024089639A1
(en)
|
2022-10-26 |
2024-05-02 |
Novartis Ag |
Lentiviral formulations
|
WO2024092145A1
(en)
|
2022-10-28 |
2024-05-02 |
Kite Pharma, Inc. |
Expedited administration of engineered lymphocytes
|
WO2024091669A1
(en)
|
2022-10-28 |
2024-05-02 |
Ginkgo Bioworks, Inc. |
Chimeric antigen receptors comprising an intracellular domain pair
|
US20240158869A1
(en)
|
2022-10-28 |
2024-05-16 |
Kite Pharma, Inc. |
Factors for optimizing immunotherapy
|
WO2024092152A1
(en)
|
2022-10-28 |
2024-05-02 |
Kite Pharma, Inc. |
Improving efficacy and durable response of immunotherapy
|
WO2024097311A2
(en)
|
2022-11-02 |
2024-05-10 |
Sana Biotechnology, Inc. |
Hypoimmunogenic mail cells, methods of making and methods of using same
|
WO2024097905A1
(en)
|
2022-11-02 |
2024-05-10 |
Celgene Corporation |
Methods of treatment with t cell therapy and immunomodulatory agent maintenance therapy
|
WO2024098024A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
WO2024100604A1
(en)
|
2022-11-09 |
2024-05-16 |
Juno Therapeutics Gmbh |
Methods for manufacturing engineered immune cells
|
WO2024102948A1
(en)
|
2022-11-11 |
2024-05-16 |
Celgene Corporation |
Fc receptor-homolog 5 (fcrh5) specific binding molecules and bispecific t-cell engaging antibodies including same and related methods
|
WO2024107646A1
(en)
|
2022-11-14 |
2024-05-23 |
Caribou Biosciences, Inc. |
Anti-cll-1 chimeric antigen receptors, engineered cells and related methods
|
TW202430148A
(zh)
|
2022-11-22 |
2024-08-01 |
美商皮克醫療公司 |
eIF4E抑制劑及其用途
|
WO2024118593A1
(en)
|
2022-11-28 |
2024-06-06 |
Allogene Therapeutics Inc. |
Claudin 18.2 targeting chimeric antigen receptors and binding agents and uses thereof
|
WO2024119074A1
(en)
|
2022-12-01 |
2024-06-06 |
Generation Bio Co. |
Stealth lipid nanoparticle compositions for cell targeting
|
WO2024124044A1
(en)
|
2022-12-07 |
2024-06-13 |
The Brigham And Women’S Hospital, Inc. |
Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression
|
WO2024124132A1
(en)
|
2022-12-09 |
2024-06-13 |
Juno Therapeutics, Inc. |
Machine learning methods for predicting cell phenotype using holographic imaging
|
WO2024129778A2
(en)
|
2022-12-13 |
2024-06-20 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for baff-r and cd19 and methods and uses thereof
|
WO2024137852A1
(en)
|
2022-12-22 |
2024-06-27 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
WO2024151541A1
(en)
|
2023-01-09 |
2024-07-18 |
Sana Biotechnology, Inc. |
Type-1 diabetes autoimmune mouse
|
WO2024155821A1
(en)
|
2023-01-18 |
2024-07-25 |
Yale University |
Chimeric antigen receptors (car) with intrinsically disordered regions and methods of use thereof
|
WO2024161021A1
(en)
|
2023-02-03 |
2024-08-08 |
Juno Therapeutics Gmbh |
Methods for non-viral manufacturing of engineered immune cells
|
WO2024178128A1
(en)
*
|
2023-02-22 |
2024-08-29 |
Elysion Therapeutics, Inc. |
Lysis sensing receptors and uses thereof
|
WO2024178397A2
(en)
|
2023-02-24 |
2024-08-29 |
Elevatebio Technologies, Inc. |
Modified immune effector cells and methods of use
|
WO2024182539A1
(en)
|
2023-02-28 |
2024-09-06 |
Lyell Immunopharma, Inc. |
Methods of culturing reprogrammed cells
|
US20240285762A1
(en)
|
2023-02-28 |
2024-08-29 |
Juno Therapeutics, Inc. |
Cell therapy for treating systemic autoimmune diseases
|
US20240342284A1
(en)
|
2023-03-03 |
2024-10-17 |
Arsenal Biosciences, Inc. |
Systems targeting psma and ca9
|
US20240343820A1
(en)
|
2023-03-09 |
2024-10-17 |
Kite Pharma, Inc. |
Antigen binding molecules and methods of use
|
WO2024192100A1
(en)
|
2023-03-13 |
2024-09-19 |
Arsenal Biosciences, Inc. |
Synthetic pathway activators
|
US20240309428A1
(en)
|
2023-03-17 |
2024-09-19 |
Kite Pharma, Inc. |
Impact of tumor microenvironment on efficacy of immunotherapy
|
WO2024194471A1
(en)
|
2023-03-23 |
2024-09-26 |
Alentis Therapeutics Ag |
Biomarker for cancer treatment using anti-claudin-1 antibodies
|
WO2024206155A1
(en)
|
2023-03-24 |
2024-10-03 |
Cornell University |
Utilizing t cells derived from tumor draining lymph nodes for chimeric antigen receptor (car) t cell therapy for the treatment of cancer
|
WO2024211478A1
(en)
|
2023-04-07 |
2024-10-10 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer with a lymphotoxin beta receptor agonist
|
WO2024215754A1
(en)
|
2023-04-11 |
2024-10-17 |
Gilead Sciences, Inc. |
Kras modulating compounds
|
WO2024215987A1
(en)
|
2023-04-14 |
2024-10-17 |
Sotio Biotech Inc. |
IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
|
WO2024215989A1
(en)
|
2023-04-14 |
2024-10-17 |
Sotio Biotech Inc. |
ENGINEERED IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-2/IL-15 RECEPTOR βγ AGONISTS
|
WO2024220588A1
(en)
|
2023-04-18 |
2024-10-24 |
Juno Therapeutics, Inc. |
Cytotoxicity assay for assessing potency of therapeutic cell compositions
|
WO2024220598A2
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Lentiviral vectors with two or more genomes
|
WO2024220574A1
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Universal protein g fusogens and adapter systems thereof and related lipid particles and uses
|
WO2024220597A2
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Digital droplet based assay for detecting replication competent lentiviral vector
|
WO2024220560A1
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Engineered protein g fusogens and related lipid particles and methods thereof
|
WO2024220917A1
(en)
|
2023-04-21 |
2024-10-24 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
WO2024220619A1
(en)
|
2023-04-21 |
2024-10-24 |
Kite Pharma, Inc. |
Allogenic therapeutic cells with reduced risk of immune rejection
|
WO2024226827A2
(en)
|
2023-04-25 |
2024-10-31 |
Arsenal Biosciences, Inc. |
Novel receptors for transcription regulation
|
WO2024226858A1
(en)
|
2023-04-26 |
2024-10-31 |
Juno Therapeutics, Inc. |
Methods for viral vector manufacturing
|
WO2024226829A2
(en)
|
2023-04-26 |
2024-10-31 |
Yale University |
Enpp3-binding molecules, compositions formed therefrom, and methods of use thereof for the treatment of cancer
|
WO2024224359A1
(en)
|
2023-04-27 |
2024-10-31 |
Takeda Pharmaceutical Company Limited |
Method for expanding cd56+/cd3- cells
|