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ES2096749T3 - Cadenas quimericas para vias de transduccion de señal asociada a un receptor. - Google Patents

Cadenas quimericas para vias de transduccion de señal asociada a un receptor.

Info

Publication number
ES2096749T3
ES2096749T3 ES92903452T ES92903452T ES2096749T3 ES 2096749 T3 ES2096749 T3 ES 2096749T3 ES 92903452 T ES92903452 T ES 92903452T ES 92903452 T ES92903452 T ES 92903452T ES 2096749 T3 ES2096749 T3 ES 2096749T3
Authority
ES
Spain
Prior art keywords
region
extracellular
receiver
signal transduction
chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92903452T
Other languages
English (en)
Inventor
Daniel J Capon
Arthur Weiss
Brian A Irving
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Cell Genesys Inc
Original Assignee
University of California
Cell Genesys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24515497&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2096749(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of California, Cell Genesys Inc filed Critical University of California
Application granted granted Critical
Publication of ES2096749T3 publication Critical patent/ES2096749T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70535Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70514CD4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/32Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE SUMINISTRAN PROTEINAS QUIMERICAS Y SECUENCIAS DE DNA QUE CODIFICAN PROTEINAS QUIMERICAS, EN DONDE LAS PROTEINAS QUIMERICAS SE CARACTERIZAN POR UNA REGION EXTRACELULAR CAPAZ DE UNIRSE A UN LIGANTE, UNA REGION DE TRANSMEMBRANA Y UNA REGION CITOPLASMICA CAPAZ DE ACTIVAR UNA LINEA DE SEÑALIZACION. LA REGION EXTRACELULAR Y LA REGION CITOPLASMICA NO SE ENCUENTRAN JUNTAS DE FORMA NATURAL. LA UNION DEL LIGANTE A LA REGION EXTRACELULAR DA COMO RESULTADO LA TRANSDUCCION DE UNA SEÑAL Y LA ACTIVACION DE UNA LINEA DE SEÑALIZACION EN LA CELULA, MEDIANTE LA CUAL LA CELULA PUEDE SER INDUCIDA A ABANDONAR VARIAS FUNCIONES RELATIVAS A LA LINEA DE SEÑALIZACION. UNA AMPLIA VARIEDAD DE REGIONES EXTRACELULARES PUEDEN EMPLEARSE COMO RECEPTORES, DICHA REGIONES PUEDEN PRODUCIRSE DE FORMA NATURAL O SINTETICA.
ES92903452T 1990-12-14 1991-12-12 Cadenas quimericas para vias de transduccion de señal asociada a un receptor. Expired - Lifetime ES2096749T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62764390A 1990-12-14 1990-12-14

Publications (1)

Publication Number Publication Date
ES2096749T3 true ES2096749T3 (es) 1997-03-16

Family

ID=24515497

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92903452T Expired - Lifetime ES2096749T3 (es) 1990-12-14 1991-12-12 Cadenas quimericas para vias de transduccion de señal asociada a un receptor.

Country Status (13)

Country Link
US (1) US5359046A (es)
EP (2) EP0517895B1 (es)
JP (1) JP3242916B2 (es)
KR (1) KR100246529B1 (es)
AT (1) ATE145428T1 (es)
AU (1) AU643109B2 (es)
CA (1) CA2074825C (es)
DE (1) DE69123241T2 (es)
DK (1) DK0517895T3 (es)
ES (1) ES2096749T3 (es)
GR (1) GR3022538T3 (es)
NO (1) NO308618B1 (es)
WO (1) WO1992010591A1 (es)

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ATE145428T1 (de) 1996-12-15
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