EG24851A - Crystalline anticholinergic process for the preparation thereof for preparing a medicament - Google Patents

Crystalline anticholinergic process for the preparation thereof for preparing a medicament

Info

Publication number: EG24851A
Authority: EG; Egypt
Prior art keywords: medicament; preparing; preparation; anticholinergic; crystalline
Prior art date: 2001-06-22

Application number

EG2002060698A

Other languages

English (en)

Inventor

Peter Sieger

Ulrike Werthmann

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-22

Filing date

2002-06-19

Publication date

2010-10-27

2002-06-19 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2010-10-27 Application granted granted Critical

2010-10-27 Publication of EG24851A publication Critical patent/EG24851A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pulmonology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)

EG2002060698A 2001-06-22 2002-06-19 Crystalline anticholinergic process for the preparation thereof for preparing a medicament EG24851A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10129710		2001-06-22
DE10215436		2002-04-08

Publications (1)

Publication Number	Publication Date
EG24851A true EG24851A (en)	2010-10-27

Family

ID=26009556

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG2002060698A EG24851A (en)	2001-06-22	2002-06-19	Crystalline anticholinergic process for the preparation thereof for preparing a medicament

Country Status (38)

Country	Link
EP (1)	EP1401445B1 (ru)
JP (1)	JP2005504015A (ru)
KR (2)	KR100971616B1 (ru)
CN (1)	CN100586948C (ru)
AR (1)	AR037491A1 (ru)
AT (1)	ATE337006T1 (ru)
AU (1)	AU2002345016B2 (ru)
BG (1)	BG66303B1 (ru)
BR (1)	BR0210537A (ru)
CA (1)	CA2450961C (ru)
CO (1)	CO5550423A2 (ru)
CY (1)	CY1105223T1 (ru)
CZ (1)	CZ302786B6 (ru)
DE (1)	DE50207943D1 (ru)
DK (1)	DK1401445T3 (ru)
EA (1)	EA005813B1 (ru)
EE (1)	EE05316B1 (ru)
EG (1)	EG24851A (ru)
ES (1)	ES2271280T3 (ru)
HK (1)	HK1068540A1 (ru)
HR (1)	HRP20031066B1 (ru)
HU (1)	HUP0400333A3 (ru)
IL (2)	IL159238A0 (ru)
ME (1)	ME00412B (ru)
MX (1)	MXPA03011718A (ru)
MY (1)	MY122779A (ru)
NO (1)	NO334301B1 (ru)
NZ (1)	NZ530690A (ru)
PE (2)	PE20081305A1 (ru)
PL (1)	PL208137B1 (ru)
PT (1)	PT1401445E (ru)
RS (1)	RS50441B (ru)
SA (1)	SA02230255B1 (ru)
SI (1)	SI1401445T1 (ru)
SK (1)	SK287262B6 (ru)
TW (2)	TWI261589B (ru)
UY (1)	UY27342A1 (ru)
WO (1)	WO2003000265A1 (ru)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10212264A1 (de)	2002-03-20	2003-10-02	Boehringer Ingelheim Pharma	Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
US7056916B2 (en)	2002-11-15	2006-06-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments for the treatment of chronic obstructive pulmonary disease
US20050038004A1 (en) *	2003-07-31	2005-02-17	Robinson Cynthia B.	Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
WO2005042527A1 (de) *	2003-11-03	2005-05-12	Boehringer Ingelheim International Gmbh	Neues kristallines anhydrat mit anticholinerger wirksamkeit
DE102004016179A1 (de) *	2004-03-30	2005-10-20	Boehringer Ingelheim Pharma	Verbindungen zur Behandlung von proliferativen Prozessen
KR101287460B1 (ko)	2004-04-22	2013-07-23	베링거 인겔하임 인터내셔날 게엠베하	벤즈옥사진을 함유하는 호흡기 질환 치료용 약제학적배합물
DE102004024454A1 (de)	2004-05-14	2005-12-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US7220742B2 (en)	2004-05-14	2007-05-22	Boehringer Ingelheim International Gmbh	Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
ATE427108T1 (de)	2004-08-11	2009-04-15	Boehringer Ingelheim Pharma	Anticholinergika enthaltende arzneimittel zur behandlung von krankheiten der ableitenden harnwege
US20060079544A1 (en) *	2004-08-13	2006-04-13	Boehringer Ingelheim International Gmbh	Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
DE102004048389A1 (de)	2004-10-01	2006-04-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
KR101335964B1 (ko)	2005-04-21	2013-12-04	베링거 인겔하임 인터내셔날 게엠베하	염증성 질환 치료용 디하이드로티에노피리미딘
MX2007012907A (es)	2005-04-28	2008-03-14	Boehringer Ingelheim Int	Nuevos compuestos para el tratamiento de enfermedades inflamatorias.
BRPI0609295A2 (pt) *	2005-05-02	2010-03-23	Boehringer Ingelheim Int	formas cristalinas de brometo de tiotràpio, composiÇço farmacÊutica, uso e mÉtodo para preparar as mesmas
CN101203513A (zh) *	2005-05-02	2008-06-18	贝林格尔·英格海姆国际有限公司	噻托溴铵的晶型
DE102005030733A1 (de)	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
RU2412176C2 (ru)	2005-08-15	2011-02-20	Бёрингер Ингельхайм Интернациональ Гмбх	Способ получения бетамиметиков
US20070086957A1 (en)	2005-10-10	2007-04-19	Thierry Bouyssou	Combination of medicaments for the treatment of respiratory diseases
US7423146B2 (en)	2005-11-09	2008-09-09	Boehringer Ingelheim International Gmbh	Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
US9108962B2 (en)	2005-12-19	2015-08-18	Sicor, Inc.	Forms of tiotropium bromide and processes for preparation thereof
WO2007075858A2 (en)	2005-12-19	2007-07-05	Sicor Inc.	Novel forms of tiotropium bromide and processes for preparation thereof
CN100999521B (zh) *	2006-01-13	2010-12-08	江苏正大天晴药业股份有限公司	结晶性抗胆碱药噻托溴铵
EP1847543A1 (de)	2006-04-19	2007-10-24	Boehringer Ingelheim Pharma GmbH & Co. KG	Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
ATE505193T1 (de)	2006-08-07	2011-04-15	Boehringer Ingelheim Int	Arzneimittelkombinationen zur behandlung von atemwegserkrankungen
UY30550A1 (es)	2006-08-22	2008-03-31	Boehringer Ingelheim Int	Nuevos beta-agonistas enantioméricamente puros, procedimientos para su preparacion y su uso como medicamentos
GB0716026D0 (en)	2007-08-16	2007-09-26	Norton Healthcare Ltd	An inhalable medicament
NZ585346A (en)	2007-10-19	2011-09-30	Boehringer Ingelheim Int	Substituted piperidino-dihydrothienopyrimidines
EP2093219A1 (de)	2008-02-22	2009-08-26	Boehringer Ingelheim International Gmbh	Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
MA33085B1 (fr)	2008-12-19	2012-03-01	Boehringer Ingelheim Int	Pyrimidine-4 carboxamides cycliques en tant qu'antagonistes du recepteur ccr2 pour le traitement d'inflammations, de l'asthme et des broncho-pneumopathies chroniques obstructives
EP2403851B1 (en)	2009-03-06	2015-06-17	Mahmut Bilgic	New crystalline forms of tiotropium bromide
EP2513086B1 (en)	2009-12-17	2015-04-29	Boehringer Ingelheim International GmbH	Novel antagonists for ccr2 and uses thereof
EP3091012B1 (en)	2009-12-17	2018-04-11	Centrexion Therapeutics Corporation	Ccr2 receptor antagonists and uses thereof
BR112012018865A2 (pt)	2010-01-29	2016-04-12	Boehringer Ingelheim Int	naftiridinas substituídas e seu uso como inibidores de quinase syk
US8877745B2 (en)	2010-05-12	2014-11-04	Boehringer Ingelheim International Gmbh	CCR2 receptor antagonists, method for producing the same, and use thereof as medicaments
US8946218B2 (en)	2010-05-12	2015-02-03	Boehringer Ingelheim International Gmbh	CCR2 receptor antagonists, method for producing the same, and use thereof as medicaments
EP2571870B1 (en)	2010-05-17	2015-01-21	Boehringer Ingelheim International GmbH	Ccr2 antagonists and uses thereof
US9018212B2 (en)	2010-05-25	2015-04-28	Boehringer Ingelheim International Gmbh	Pyridazine carboxamides as CCR2 receptor antagonists
US8962656B2 (en)	2010-06-01	2015-02-24	Boehringer Ingelheim International Gmbh	CCR2 antagonists
TR201007108A2 (tr) *	2010-08-25	2012-03-21	B�Lg�� Mahmut	Yeni tiotropyum bromür kristali ve üretim yöntemi.@
EP2668177B1 (en)	2011-01-28	2014-10-22	Boehringer Ingelheim International GmbH	Substituted pyridinyl-pyrimidines and their use as medicaments
TR201101897A2 (tr)	2011-02-28	2012-09-21	Bi̇lgi̇ç Mahmut	Tiotropyum bromür içeren kristal madde
TR201102068A2 (tr)	2011-03-03	2012-09-21	Bi̇lgi̇ç Mahmut	Tiotropyum bromür içeren kristal maddeler
TR201111589A2 (tr) *	2011-03-03	2012-09-21	Bi̇lgi̇ç Mahmut	Tiotropyum bromür susuz kristal formu.
WO2012171863A1 (en)	2011-06-16	2012-12-20	Boehringer Ingelheim International Gmbh	New selective ccr2 antagonists
JP5786258B2 (ja)	2011-07-15	2015-09-30	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規かつ選択的なｃｃｒ２拮抗薬
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US20130059866A1 (en)	2011-08-24	2013-03-07	Boehringer Ingelheim International Gmbh	Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
CU24354B1 (es)	2011-11-25	2018-08-06	Adverio Pharma Gmbh	Procedimiento de obtención de derivados de tetrafluoropropilmorfolina
CZ304368B6 (cs)	2011-11-28	2014-04-02	Zentiva, K.S.	Směsný solvát tiotropium bromidu a způsob jeho přípravy
GB201200525D0 (en)	2011-12-19	2012-02-29	Teva Branded Pharmaceutical Prod R & D Inc	An inhalable medicament
PT106142B (pt) *	2012-02-10	2014-07-18	Hovione Farmaci Ncia S A	Processo para a preparação de brometo de tiotrópio
US9096579B2 (en)	2012-04-20	2015-08-04	Boehringer Ingelheim International Gmbh	Amino-indolyl-substituted imidazolyl-pyrimidines and their use as medicaments
WO2014042605A1 (en) *	2012-09-11	2014-03-20	Mahmut Bilgic	New tiotropium bromide crystalline form
HUE032455T2 (en)	2012-11-05	2017-09-28	Zentiva Ks	Stabilization of thiotropium solvates
CN104341412A (zh) *	2013-07-29	2015-02-11	天津金耀集团有限公司	一种无水噻托溴铵结晶的制备方法
DK3119772T3 (da)	2014-03-19	2019-08-26	Boehringer Ingelheim Int	Heteroaryl syk-hæmmere
US10034866B2 (en)	2014-06-19	2018-07-31	Teva Branded Pharmaceutical Products R&D, Inc.	Inhalable medicament comprising tiotropium
MY192216A (en)	2014-10-21	2022-08-09	Takeda Pharmaceuticals Co	Crystalline forms of 5-chloro-n4-[-2-(dimethylphosphoryl) phenyl]-n2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl) piperidin-1-yl] pyrimidine-2,4-diamine
EP3414243A1 (en) *	2016-02-11	2018-12-19	Sima Patent Ve Lisanslama Hizmetleri Ltd. STI	Crystalline form of tiotropium bromide anhydrate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3931041C2 (de) *	1989-09-16	2000-04-06	Boehringer Ingelheim Kg	Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
WO2002030928A1 (de) *	2000-10-12	2002-04-18	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Kristallines monohydrat, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels
DE10064816A1 (de) *	2000-12-22	2002-06-27	Boehringer Ingelheim Pharma	Verfahren zur Herstellung eines Anticholinergikums

2002
- 2002-06-08 IL IL15923802A patent/IL159238A0/xx unknown
- 2002-06-08 SI SI200230431T patent/SI1401445T1/sl unknown
- 2002-06-08 EP EP02743165A patent/EP1401445B1/de not_active Expired - Lifetime
- 2002-06-08 HU HU0400333A patent/HUP0400333A3/hu unknown
- 2002-06-08 CZ CZ20040120A patent/CZ302786B6/cs not_active IP Right Cessation
- 2002-06-08 DE DE50207943T patent/DE50207943D1/de not_active Expired - Lifetime
- 2002-06-08 CN CN02812303A patent/CN100586948C/zh not_active Expired - Lifetime
- 2002-06-08 KR KR1020037016769A patent/KR100971616B1/ko active IP Right Grant
- 2002-06-08 DK DK02743165T patent/DK1401445T3/da active
- 2002-06-08 ES ES02743165T patent/ES2271280T3/es not_active Expired - Lifetime
- 2002-06-08 EE EEP200400029A patent/EE05316B1/xx unknown
- 2002-06-08 JP JP2003506910A patent/JP2005504015A/ja active Pending
- 2002-06-08 BR BR0210537-3A patent/BR0210537A/pt active Pending
- 2002-06-08 MX MXPA03011718A patent/MXPA03011718A/es active IP Right Grant
- 2002-06-08 NZ NZ530690A patent/NZ530690A/en not_active IP Right Cessation
- 2002-06-08 AU AU2002345016A patent/AU2002345016B2/en not_active Expired
- 2002-06-08 CA CA2450961A patent/CA2450961C/en not_active Expired - Fee Related
- 2002-06-08 PT PT02743165T patent/PT1401445E/pt unknown
- 2002-06-08 WO PCT/EP2002/006291 patent/WO2003000265A1/de active Application Filing
- 2002-06-08 PL PL364489A patent/PL208137B1/pl unknown
- 2002-06-08 AT AT02743165T patent/ATE337006T1/de active
- 2002-06-08 RS YUP-997/03A patent/RS50441B/sr unknown
- 2002-06-08 ME MEP-2008-620A patent/ME00412B/me unknown
- 2002-06-08 KR KR1020097004823A patent/KR101011353B1/ko active IP Right Grant
- 2002-06-08 SK SK52-2004A patent/SK287262B6/sk unknown
- 2002-06-08 EA EA200301293A patent/EA005813B1/ru not_active IP Right Cessation
- 2002-06-19 TW TW091113373A patent/TWI261589B/zh not_active IP Right Cessation
- 2002-06-19 EG EG2002060698A patent/EG24851A/xx active
- 2002-06-19 TW TW095100968A patent/TW200617007A/zh unknown
- 2002-06-20 UY UY27342A patent/UY27342A1/es not_active Application Discontinuation
- 2002-06-20 MY MYPI20022316A patent/MY122779A/en unknown
- 2002-06-21 PE PE2007000660A patent/PE20081305A1/es not_active Application Discontinuation
- 2002-06-21 PE PE2002000538A patent/PE20030130A1/es active IP Right Grant
- 2002-06-21 AR ARP020102337A patent/AR037491A1/es not_active Ceased/Invalidation/Refusal/Rejection/Nullification
- 2002-08-19 SA SA2230255A patent/SA02230255B1/ar unknown
2003
- 2003-12-08 IL IL159238A patent/IL159238A/en active IP Right Grant
- 2003-12-12 BG BG108440A patent/BG66303B1/bg active Active
- 2003-12-19 HR HR20031066A patent/HRP20031066B1/xx not_active IP Right Cessation
- 2003-12-19 NO NO20035696A patent/NO334301B1/no not_active IP Right Cessation
2004
- 2004-01-20 CO CO04003764A patent/CO5550423A2/es not_active Application Discontinuation
2005
- 2005-01-29 HK HK05100780.9A patent/HK1068540A1/xx not_active IP Right Cessation
2006
- 2006-09-20 CY CY20061101339T patent/CY1105223T1/el unknown

Also Published As

Publication number	Publication date
UY27342A1 (es)	2003-02-28
HK1068540A1 (en)	2005-04-29
HUP0400333A3 (en)	2012-10-29
PT1401445E (pt)	2006-10-31
PE20030130A1 (es)	2003-04-02
JP2005504015A (ja)	2005-02-10
NO20035696D0 (no)	2003-12-19
ME00412B (me)	2011-10-10
NZ530690A (en)	2005-05-27
IL159238A0 (en)	2004-06-01
WO2003000265A1 (de)	2003-01-03
DK1401445T3 (da)	2006-11-27
KR100971616B1 (ko)	2010-07-22
MXPA03011718A (es)	2004-12-06
NO334301B1 (no)	2014-02-03
TWI261589B (en)	2006-09-11
IL159238A (en)	2010-04-15
KR20040018285A (ko)	2004-03-02
SK522004A3 (en)	2004-06-08
EP1401445B1 (de)	2006-08-23
SK287262B6 (sk)	2010-04-07
SI1401445T1 (sl)	2007-02-28
RS50441B (sr)	2010-03-02
ES2271280T3 (es)	2007-04-16
EA200301293A1 (ru)	2004-08-26
CA2450961A1 (en)	2003-01-03
BG108440A (en)	2004-08-31
KR101011353B1 (ko)	2011-01-28
DE50207943D1 (de)	2006-10-05
CO5550423A2 (es)	2005-08-31
EP1401445A1 (de)	2004-03-31
HUP0400333A2 (hu)	2004-12-28
BG66303B1 (bg)	2013-03-29
BR0210537A (pt)	2004-06-22
MEP62008A (en)	2011-05-10
PL364489A1 (en)	2004-12-13
PE20081305A1 (es)	2008-10-01
CZ302786B6 (cs)	2011-11-09
HRP20031066B1 (en)	2011-10-31
MY122779A (en)	2006-05-31
YU99703A (sh)	2006-05-25
CN100586948C (zh)	2010-02-03
AU2002345016B2 (en)	2008-04-17
EE05316B1 (et)	2010-08-16
CY1105223T1 (el)	2010-03-03
TW200617007A (en)	2006-06-01
ATE337006T1 (de)	2006-09-15
EE200400029A (et)	2004-04-15
PL208137B1 (pl)	2011-03-31
SA02230255B1 (ar)	2006-10-31
KR20090031638A (ko)	2009-03-26
HRP20031066A2 (en)	2004-04-30
CN1520294A (zh)	2004-08-11
CA2450961C (en)	2010-03-30
EA005813B1 (ru)	2005-06-30
AR037491A1 (es)	2004-11-17
CZ2004120A3 (cs)	2004-05-12

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