DK1401445T3 - Krystallinsk anticholinergikum, fremgangsmåde til fremstilling af dette og anvendelse af dette til fremstilling af et lægemiddel - Google Patents

Krystallinsk anticholinergikum, fremgangsmåde til fremstilling af dette og anvendelse af dette til fremstilling af et lægemiddel

Info

Publication number: DK1401445T3
Authority: DK; Denmark
Prior art keywords: drug; prepare; preparing; anticholinergic; crystalline
Prior art date: 2001-06-22

Application number

DK02743165T

Other languages

Danish (da)

English (en)

Inventor

Ulrike Werthmann

Peter Sieger

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-22

Filing date

2002-06-08

Publication date

2006-11-27

2002-06-08 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2006-11-27 Application granted granted Critical

2006-11-27 Publication of DK1401445T3 publication Critical patent/DK1401445T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pulmonology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)

DK02743165T 2001-06-22 2002-06-08 Krystallinsk anticholinergikum, fremgangsmåde til fremstilling af dette og anvendelse af dette til fremstilling af et lægemiddel DK1401445T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10129710		2001-06-22
DE10215436		2002-04-08

Publications (1)

Publication Number	Publication Date
DK1401445T3 true DK1401445T3 (da)	2006-11-27

Family

ID=26009556

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02743165T DK1401445T3 (da)	2001-06-22	2002-06-08	Krystallinsk anticholinergikum, fremgangsmåde til fremstilling af dette og anvendelse af dette til fremstilling af et lægemiddel

Country Status (37)

Country	Link
EP (1)	EP1401445B1 (ru)
JP (1)	JP2005504015A (ru)
KR (2)	KR101011353B1 (ru)
CN (1)	CN100586948C (ru)
AR (1)	AR037491A1 (ru)
AT (1)	ATE337006T1 (ru)
AU (1)	AU2002345016B2 (ru)
BG (1)	BG66303B1 (ru)
BR (1)	BR0210537A (ru)
CA (1)	CA2450961C (ru)
CO (1)	CO5550423A2 (ru)
CY (1)	CY1105223T1 (ru)
CZ (1)	CZ302786B6 (ru)
DE (1)	DE50207943D1 (ru)
DK (1)	DK1401445T3 (ru)
EA (1)	EA005813B1 (ru)
EE (1)	EE05316B1 (ru)
EG (1)	EG24851A (ru)
ES (1)	ES2271280T3 (ru)
HR (1)	HRP20031066B1 (ru)
HU (1)	HUP0400333A3 (ru)
IL (2)	IL159238A0 (ru)
ME (1)	ME00412B (ru)
MX (1)	MXPA03011718A (ru)
MY (1)	MY122779A (ru)
NO (1)	NO334301B1 (ru)
NZ (1)	NZ530690A (ru)
PE (2)	PE20030130A1 (ru)
PL (1)	PL208137B1 (ru)
PT (1)	PT1401445E (ru)
RS (1)	RS50441B (ru)
SA (1)	SA02230255B1 (ru)
SI (1)	SI1401445T1 (ru)
SK (1)	SK287262B6 (ru)
TW (2)	TW200617007A (ru)
UY (1)	UY27342A1 (ru)
WO (1)	WO2003000265A1 (ru)

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DE10212264A1 (de)	2002-03-20	2003-10-02	Boehringer Ingelheim Pharma	Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
US7056916B2 (en)	2002-11-15	2006-06-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments for the treatment of chronic obstructive pulmonary disease
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UA82909C2 (en) *	2003-11-03	2008-05-26	Boehringer Ingelheim Int	Novel crystalline anhydride with anticholinergic effect
DE102004016179A1 (de) *	2004-03-30	2005-10-20	Boehringer Ingelheim Pharma	Verbindungen zur Behandlung von proliferativen Prozessen
CA2559699C (en)	2004-04-22	2012-06-19	Boehringer Ingelheim International Gmbh	Pharmaceutical combinations containing benzoxazine for treating respiratory diseases
DE102004024454A1 (de)	2004-05-14	2005-12-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US7220742B2 (en)	2004-05-14	2007-05-22	Boehringer Ingelheim International Gmbh	Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
ES2322148T3 (es)	2004-08-11	2009-06-17	BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG	Medicamentos que contienen anticolinergicos para el tratamiento en las vias urinarias.
US20060079544A1 (en) *	2004-08-13	2006-04-13	Boehringer Ingelheim International Gmbh	Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
DE102004048389A1 (de)	2004-10-01	2006-04-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
CN101163706A (zh)	2005-04-21	2008-04-16	贝林格尔·英格海姆国际有限公司	用于治疗炎性疾病的二氢噻吩并嘧啶
NZ563448A (en)	2005-04-28	2011-01-28	Boehringer Ingelheim Int	Benzofuranone derivatives for treating inflammatory diseases
CN101166738B (zh) *	2005-05-02	2011-06-01	贝林格尔·英格海姆国际有限公司	噻托溴铵的新晶型
MX2007013691A (es) *	2005-05-02	2008-01-21	Boehringer Ingelheim Int	Nuevas formas cristalinas de bromuro de tiotropio.
DE102005030733A1 (de)	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
KR101360803B1 (ko)	2005-08-15	2014-02-11	베링거 인겔하임 인터내셔날 게엠베하	베타모방제의 제조방법
US20070086957A1 (en)	2005-10-10	2007-04-19	Thierry Bouyssou	Combination of medicaments for the treatment of respiratory diseases
US7423146B2 (en)	2005-11-09	2008-09-09	Boehringer Ingelheim International Gmbh	Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
TW200732340A (en) *	2005-12-19	2007-09-01	Sicor Inc	Novel forms of tiotropium bromide and processes for preparation thereof
US9108962B2 (en)	2005-12-19	2015-08-18	Sicor, Inc.	Forms of tiotropium bromide and processes for preparation thereof
CN100999521B (zh) *	2006-01-13	2010-12-08	江苏正大天晴药业股份有限公司	结晶性抗胆碱药噻托溴铵
EP1847543A1 (de)	2006-04-19	2007-10-24	Boehringer Ingelheim Pharma GmbH & Co. KG	Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
EP2051714B1 (de)	2006-08-07	2011-04-13	Boehringer Ingelheim International GmbH	Arzneimittelkombinationen zur behandlung von atemwegserkrankungen
PE20080610A1 (es)	2006-08-22	2008-07-15	Boehringer Ingelheim Int	Nuevos beta-agonistas enantiomericamente puros, procedimientos para su preparacion y uso como medicamentos
GB0716026D0 (en)	2007-08-16	2007-09-26	Norton Healthcare Ltd	An inhalable medicament
PT2215092E (pt)	2007-10-19	2012-04-10	Boehringer Ingelheim Int	Piperidino-di-hidrotienopirimidinas substituídas
EP2093219A1 (de)	2008-02-22	2009-08-26	Boehringer Ingelheim International Gmbh	Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
BRPI0923051B1 (pt)	2008-12-19	2022-07-19	Centrexion Therapeutics Corporation	Pirimidin-4-carboxamidas cíclicas como antagonistas do receptor de ccr2 para o tratamento de inflamação, asma e copd, seu uso, formulação e combinação farmacêutica que os compreende
EP2403851B1 (en)	2009-03-06	2015-06-17	Mahmut Bilgic	New crystalline forms of tiotropium bromide
EP2513086B1 (en)	2009-12-17	2015-04-29	Boehringer Ingelheim International GmbH	Novel antagonists for ccr2 and uses thereof
DK2513093T3 (da)	2009-12-17	2014-09-29	Boehringer Ingelheim Int	Nye CCR2 receptor antagonister og anvendelser deraf
EP2528915B1 (en)	2010-01-29	2015-10-28	Boehringer Ingelheim International GmbH	Substituted naphthyridines and their use as syk kinase inhibitors
JP2013526507A (ja)	2010-05-12	2013-06-24	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規ｃｃｒ２受容体アンタゴニスト、その製造方法及び薬物としてのその使用
US8946218B2 (en)	2010-05-12	2015-02-03	Boehringer Ingelheim International Gmbh	CCR2 receptor antagonists, method for producing the same, and use thereof as medicaments
US8841313B2 (en)	2010-05-17	2014-09-23	Boehringer Ingelheim International Gmbh	CCR2 antagonists and uses thereof
US9018212B2 (en)	2010-05-25	2015-04-28	Boehringer Ingelheim International Gmbh	Pyridazine carboxamides as CCR2 receptor antagonists
WO2011151251A1 (en)	2010-06-01	2011-12-08	Boehringer Ingelheim International Gmbh	New ccr2 antagonists
TR201007108A2 (tr) *	2010-08-25	2012-03-21	B�Lg�� Mahmut	Yeni tiotropyum bromür kristali ve üretim yöntemi.@
EP2668177B1 (en)	2011-01-28	2014-10-22	Boehringer Ingelheim International GmbH	Substituted pyridinyl-pyrimidines and their use as medicaments
TR201101897A2 (tr)	2011-02-28	2012-09-21	Bi̇lgi̇ç Mahmut	Tiotropyum bromür içeren kristal madde
TR201102068A2 (tr)	2011-03-03	2012-09-21	Bi̇lgi̇ç Mahmut	Tiotropyum bromür içeren kristal maddeler
TR201111589A2 (tr) *	2011-03-03	2012-09-21	Bi̇lgi̇ç Mahmut	Tiotropyum bromür susuz kristal formu.
JP5786257B2 (ja)	2011-06-16	2015-09-30	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規の選択的ｃｃｒ２拮抗薬
JP5786258B2 (ja)	2011-07-15	2015-09-30	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規かつ選択的なｃｃｒ２拮抗薬
KR101986484B1 (ko)	2011-07-26	2019-06-10	베링거 인겔하임 인터내셔날 게엠베하	치환된 퀴놀린 및 이의 약제로서의 용도
US20130059866A1 (en)	2011-08-24	2013-03-07	Boehringer Ingelheim International Gmbh	Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
EP2782914B1 (de)	2011-11-25	2018-08-01	Adverio Pharma GmbH	Verfahren zur herstellung von substituierten 5-fluor-1h-pyrazolopyridinen
CZ304368B6 (cs)	2011-11-28	2014-04-02	Zentiva, K.S.	Směsný solvát tiotropium bromidu a způsob jeho přípravy
GB201200525D0 (en)	2011-12-19	2012-02-29	Teva Branded Pharmaceutical Prod R & D Inc	An inhalable medicament
PT106142B (pt) *	2012-02-10	2014-07-18	Hovione Farmaci Ncia S A	Processo para a preparação de brometo de tiotrópio
US9096579B2 (en)	2012-04-20	2015-08-04	Boehringer Ingelheim International Gmbh	Amino-indolyl-substituted imidazolyl-pyrimidines and their use as medicaments
WO2014042605A1 (en) *	2012-09-11	2014-03-20	Mahmut Bilgic	New tiotropium bromide crystalline form
HUE032455T2 (en)	2012-11-05	2017-09-28	Zentiva Ks	Stabilization of thiotropium solvates
CN104341412A (zh) *	2013-07-29	2015-02-11	天津金耀集团有限公司	一种无水噻托溴铵结晶的制备方法
EP3119765B1 (en)	2014-03-19	2019-07-17	Boehringer Ingelheim International GmbH	Heteroaryl syk inhibitors
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2002
- 2002-06-08 KR KR1020097004823A patent/KR101011353B1/ko not_active Expired - Lifetime
- 2002-06-08 EE EEP200400029A patent/EE05316B1/xx unknown
- 2002-06-08 PL PL364489A patent/PL208137B1/pl unknown
- 2002-06-08 NZ NZ530690A patent/NZ530690A/en not_active IP Right Cessation
- 2002-06-08 DK DK02743165T patent/DK1401445T3/da active
- 2002-06-08 DE DE50207943T patent/DE50207943D1/de not_active Expired - Lifetime
- 2002-06-08 PT PT02743165T patent/PT1401445E/pt unknown
- 2002-06-08 EP EP02743165A patent/EP1401445B1/de not_active Expired - Lifetime
- 2002-06-08 HU HU0400333A patent/HUP0400333A3/hu unknown
- 2002-06-08 AU AU2002345016A patent/AU2002345016B2/en not_active Expired
- 2002-06-08 ME MEP-2008-620A patent/ME00412B/me unknown
- 2002-06-08 CZ CZ20040120A patent/CZ302786B6/cs not_active IP Right Cessation
- 2002-06-08 JP JP2003506910A patent/JP2005504015A/ja active Pending
- 2002-06-08 AT AT02743165T patent/ATE337006T1/de active
- 2002-06-08 IL IL15923802A patent/IL159238A0/xx unknown
- 2002-06-08 SI SI200230431T patent/SI1401445T1/sl unknown
- 2002-06-08 HR HR20031066A patent/HRP20031066B1/xx not_active IP Right Cessation
- 2002-06-08 SK SK52-2004A patent/SK287262B6/sk unknown
- 2002-06-08 RS YUP-997/03A patent/RS50441B/sr unknown
- 2002-06-08 CN CN02812303A patent/CN100586948C/zh not_active Expired - Lifetime
- 2002-06-08 MX MXPA03011718A patent/MXPA03011718A/es active IP Right Grant
- 2002-06-08 KR KR1020037016769A patent/KR100971616B1/ko not_active Expired - Lifetime
- 2002-06-08 ES ES02743165T patent/ES2271280T3/es not_active Expired - Lifetime
- 2002-06-08 EA EA200301293A patent/EA005813B1/ru not_active IP Right Cessation
- 2002-06-08 BR BR0210537-3A patent/BR0210537A/pt active Pending
- 2002-06-08 CA CA2450961A patent/CA2450961C/en not_active Expired - Fee Related
- 2002-06-08 WO PCT/EP2002/006291 patent/WO2003000265A1/de active Application Filing
- 2002-06-19 TW TW095100968A patent/TW200617007A/zh unknown
- 2002-06-19 TW TW091113373A patent/TWI261589B/zh not_active IP Right Cessation
- 2002-06-19 EG EG2002060698A patent/EG24851A/xx active
- 2002-06-20 UY UY27342A patent/UY27342A1/es not_active Application Discontinuation
- 2002-06-20 MY MYPI20022316A patent/MY122779A/en unknown
- 2002-06-21 PE PE2002000538A patent/PE20030130A1/es active IP Right Grant
- 2002-06-21 PE PE2007000660A patent/PE20081305A1/es not_active Application Discontinuation
- 2002-06-21 AR ARP020102337A patent/AR037491A1/es not_active Ceased/Invalidation/Refusal/Rejection/Nullification
- 2002-08-19 SA SA2230255A patent/SA02230255B1/ar unknown
2003
- 2003-12-08 IL IL159238A patent/IL159238A/en active IP Right Grant
- 2003-12-12 BG BG108440A patent/BG66303B1/bg active Active
- 2003-12-19 NO NO20035696A patent/NO334301B1/no not_active IP Right Cessation
2004
- 2004-01-20 CO CO04003764A patent/CO5550423A2/es not_active Application Discontinuation
2006
- 2006-09-20 CY CY20061101339T patent/CY1105223T1/el unknown

Also Published As

Publication number	Publication date
AR037491A1 (es)	2004-11-17
HK1068540A1 (zh)	2005-04-29
MXPA03011718A (es)	2004-12-06
PL364489A1 (en)	2004-12-13
NO20035696D0 (no)	2003-12-19
KR101011353B1 (ko)	2011-01-28
TW200617007A (en)	2006-06-01
HRP20031066B1 (en)	2011-10-31
ATE337006T1 (de)	2006-09-15
CO5550423A2 (es)	2005-08-31
CZ302786B6 (cs)	2011-11-09
MEP62008A (en)	2011-05-10
SA02230255B1 (ar)	2006-10-31
BG108440A (en)	2004-08-31
PE20030130A1 (es)	2003-04-02
SK522004A3 (en)	2004-06-08
PE20081305A1 (es)	2008-10-01
NO334301B1 (no)	2014-02-03
KR100971616B1 (ko)	2010-07-22
HRP20031066A2 (en)	2004-04-30
PL208137B1 (pl)	2011-03-31
EP1401445B1 (de)	2006-08-23
KR20090031638A (ko)	2009-03-26
AU2002345016B2 (en)	2008-04-17
EE200400029A (et)	2004-04-15
ME00412B (me)	2011-10-10
UY27342A1 (es)	2003-02-28
PT1401445E (pt)	2006-10-31
ES2271280T3 (es)	2007-04-16
BG66303B1 (bg)	2013-03-29
NZ530690A (en)	2005-05-27
CY1105223T1 (el)	2010-03-03
IL159238A0 (en)	2004-06-01
IL159238A (en)	2010-04-15
MY122779A (en)	2006-05-31
CN100586948C (zh)	2010-02-03
CZ2004120A3 (cs)	2004-05-12
CA2450961C (en)	2010-03-30
EA005813B1 (ru)	2005-06-30
SI1401445T1 (sl)	2007-02-28
DE50207943D1 (de)	2006-10-05
EG24851A (en)	2010-10-27
CN1520294A (zh)	2004-08-11
EE05316B1 (et)	2010-08-16
WO2003000265A1 (de)	2003-01-03
HUP0400333A2 (hu)	2004-12-28
JP2005504015A (ja)	2005-02-10
YU99703A (sh)	2006-05-25
TWI261589B (en)	2006-09-11
RS50441B (sr)	2010-03-02
SK287262B6 (sk)	2010-04-07
KR20040018285A (ko)	2004-03-02
EP1401445A1 (de)	2004-03-31
HUP0400333A3 (en)	2012-10-29
BR0210537A (pt)	2004-06-22
CA2450961A1 (en)	2003-01-03
EA200301293A1 (ru)	2004-08-26

Publication	Publication Date	Title
DK1401445T3 (da)	2006-11-27	Krystallinsk anticholinergikum, fremgangsmåde til fremstilling af dette og anvendelse af dette til fremstilling af et lægemiddel
DK1326862T3 (da)	2004-11-22	Krystallinsk monohydrat af tiotropiumbromid, fremgangsmåde til fremstilling deraf og anvendelse deraf til fremstilling af et lægemiddel
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DK1309555T3 (da)	2005-10-24	Metode til fremstilling af amlodipinmaleat
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NO20025879D0 (no)	2002-12-06	Acylfenylureaderivater, fremgangsmåte for fremstilling derav og deres anvendelse som et legemiddel
DK1293507T3 (da)	2007-12-27	Fremgangsmåde til fremstilling af krystaller
NO20054533D0 (no)	2005-10-03	Oral insulinsammensetning og metoder for a lage og bruke den
DK1253153T3 (da)	2017-01-02	Fremgangsmåde til fremstilling af 4"-substituerede-9-deoxo-9a-aza-9a-homoerythromycin-A-derivater
NO20054220D0 (no)	2005-09-12	Substituerte N-arylheterocykler, fremgangsmate for fremstilling derav og deres anvendelse som legemiddel
DK1381351T3 (da)	2004-11-29	Fremgangsmåde til kontinuerlig fremstilling af inhalerbare medikamenter
DK1414816T3 (da)	2005-04-11	Stabil polymorf af flibanserin, teknisk fremgangsmåde til fremstilling deraf og anvendelse deraf til lægemiddelfremstilling
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DK1383482T3 (da)	2007-10-29	Fremgangsmåde til fremstilling af en farmaceutisk lavdoseringssammensætning
DK1147075T3 (da)	2003-12-08	Fremgangsmåde til fremstilling af L-phenylephrinhydrochlorid
DK1432683T3 (da)	2006-03-06	Hidtil ukendte krystallinske polymorfe former af lercanidipinhydrochlorid og fremgangsmåder til fremstilling heraf
DK2083007T3 (da)	2013-07-29	Tiotropiumsalte, fremgangsmåder til deres fremstilling og lægemiddelformuleringer indeholdende disse
DK1261318T3 (da)	2003-12-29	En koncentreret opløsning af kvaternære ammoniumforbindelser og fremgangsmåder til anvendelse
DK1575941T3 (da)	2012-07-09	Fremgangsmåde til fremstilling af (S)-pantoprazol
DK1362040T3 (da)	2005-01-24	Fremgangsmåde til fremstilling af mesylater af piperidinderivater
DK1326836T3 (da)	2004-06-01	Fremgangsmåde til fremstilling af 3-amino-2-chlor-4-methylpyridin
DK1342743T3 (da)	2008-12-15	Fremgangsmåde til fremstillinmg af et pulver med höjt tanninindhold og dets anvendelse