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DK4063397T3 - Kimære antigenreceptorer baseret på enkelt-domæneantistoffer og fremgangsmåder til anvendelse deraf - Google Patents

Kimære antigenreceptorer baseret på enkelt-domæneantistoffer og fremgangsmåder til anvendelse deraf Download PDF

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Publication number
DK4063397T3
DK4063397T3 DK22168161.2T DK22168161T DK4063397T3 DK 4063397 T3 DK4063397 T3 DK 4063397T3 DK 22168161 T DK22168161 T DK 22168161T DK 4063397 T3 DK4063397 T3 DK 4063397T3
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Denmark
Prior art keywords
methods
chimeric antigen
domain antibodies
antigen receptors
receptors based
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DK22168161.2T
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English (en)
Inventor
Xiaohu Fan
Chuan-Chu Chou
Qiuchuan Zhuang
Pingyan Wang
Lin Wang
Lei Yang
Jiaying Hao
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Legend Biotech Ireland Ltd
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Publication of DK4063397T3 publication Critical patent/DK4063397T3/da

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/27Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by targeting or presenting multiple antigens
    • A61K2239/29Multispecific CARs
    • AHUMAN NECESSITIES
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    • A61K2239/46Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/48Blood cells, e.g. leukemia or lymphoma
    • AHUMAN NECESSITIES
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
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    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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DK22168161.2T 2015-08-11 2016-08-10 Kimære antigenreceptorer baseret på enkelt-domæneantistoffer og fremgangsmåder til anvendelse deraf DK4063397T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201510490002 2015-08-11
CN201510733585.2A CN105384825B (zh) 2015-08-11 2015-11-02 一种基于单域抗体的双特异性嵌合抗原受体及其应用
EP16834662.5A EP3334765A4 (en) 2015-08-11 2016-08-10 CHIMERIC ANTIGEN RECEPTORS BASED ON INDIVIDUAL DOMAIN ANTIBODIES AND METHOD FOR USE THEREOF

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DK4063397T3 true DK4063397T3 (da) 2024-07-22

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DK22168161.2T DK4063397T3 (da) 2015-08-11 2016-08-10 Kimære antigenreceptorer baseret på enkelt-domæneantistoffer og fremgangsmåder til anvendelse deraf
DK21166662.3T DK3896091T5 (da) 2015-08-11 2017-08-10 Kimære antigenreceptorer målrettet bcma og fremgangsmåder til anvendelse deraf

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DK21166662.3T DK3896091T5 (da) 2015-08-11 2017-08-10 Kimære antigenreceptorer målrettet bcma og fremgangsmåder til anvendelse deraf

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US (5) US10934363B2 (da)
EP (7) EP4063397B1 (da)
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