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DK1669463T3 - Kaseinhydrolysat, fremgangsmåde til fremstilling af dette og anvendelse af dette - Google Patents

Kaseinhydrolysat, fremgangsmåde til fremstilling af dette og anvendelse af dette

Info

Publication number
DK1669463T3
DK1669463T3 DK04771088T DK04771088T DK1669463T3 DK 1669463 T3 DK1669463 T3 DK 1669463T3 DK 04771088 T DK04771088 T DK 04771088T DK 04771088 T DK04771088 T DK 04771088T DK 1669463 T3 DK1669463 T3 DK 1669463T3
Authority
DK
Denmark
Prior art keywords
pro
vivo
peptides
casein
amino acids
Prior art date
Application number
DK04771088T
Other languages
Danish (da)
English (en)
Inventor
Naoyuki Yamamoto
Shingo Nishimura
Tadashi Shinoda
Seiichi Mizuno
Takanobu Gotou
Keiichi Matsuura
Original Assignee
Calpis Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calpis Co Ltd filed Critical Calpis Co Ltd
Application granted granted Critical
Publication of DK1669463T3 publication Critical patent/DK1669463T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK04771088T 2003-08-01 2004-07-30 Kaseinhydrolysat, fremgangsmåde til fremstilling af dette og anvendelse af dette DK1669463T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003285007 2003-08-01
PCT/JP2004/010928 WO2005012542A1 (ja) 2003-08-01 2004-07-30 カゼイン加水分解物、その製造法及びその用途

Publications (1)

Publication Number Publication Date
DK1669463T3 true DK1669463T3 (da) 2009-01-26

Family

ID=34113859

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04771089.2T DK1661909T3 (da) 2003-08-01 2004-07-30 Biologisk ikke-nedbrydeligt peptid, angiotensinomdannende enzyminhibitor, medikament og funktionel fødevare
DK04771088T DK1669463T3 (da) 2003-08-01 2004-07-30 Kaseinhydrolysat, fremgangsmåde til fremstilling af dette og anvendelse af dette

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK04771089.2T DK1661909T3 (da) 2003-08-01 2004-07-30 Biologisk ikke-nedbrydeligt peptid, angiotensinomdannende enzyminhibitor, medikament og funktionel fødevare

Country Status (23)

Country Link
US (3) US20070122451A1 (ja)
EP (2) EP1669463B1 (ja)
JP (3) JP5341300B2 (ja)
KR (3) KR101115560B1 (ja)
CN (3) CN100439393C (ja)
AT (2) ATE442855T1 (ja)
AU (2) AU2004261522B2 (ja)
BR (2) BRPI0413242A (ja)
CA (2) CA2532537A1 (ja)
DE (2) DE602004023210D1 (ja)
DK (2) DK1661909T3 (ja)
EA (2) EA011570B1 (ja)
ES (2) ES2313067T3 (ja)
HK (2) HK1093991A1 (ja)
MX (2) MXPA06000878A (ja)
NO (2) NO20060994L (ja)
NZ (2) NZ545340A (ja)
PL (1) PL1669463T3 (ja)
PT (2) PT1661909E (ja)
TW (2) TWI349676B (ja)
UA (2) UA89616C2 (ja)
WO (2) WO2005012334A1 (ja)
ZA (2) ZA200601739B (ja)

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ZA200709009B (en) * 2005-04-28 2009-01-28 Unilever Plc Peptides having an ace inhibiting effect
ZA200708795B (en) * 2005-04-28 2009-08-26 Unilever Plc Peptides having a healthy benefit and compositions comprising them
BRPI0611469A2 (pt) * 2005-04-28 2010-09-08 Unilever Nv usos do tripeptìdeo itp e produto alimentìcio
WO2007013426A1 (ja) 2005-07-26 2007-02-01 Calpis Co., Ltd. 発酵乳の製造方法及び発酵乳飲食品
EP2630874A1 (en) * 2005-10-28 2013-08-28 Nestec S.A. Methods for the use of branched chain amino acids
EP1992354B1 (en) * 2006-02-09 2014-04-09 Calpis Co., Ltd. Rheumatoid arthritis-preventive agent for oral intake
JP4956164B2 (ja) * 2006-12-06 2012-06-20 味の素株式会社 メラニン輸送及び／又は放出抑制剤
CN101641113A (zh) * 2007-03-27 2010-02-03 卡尔皮斯株式会社 心力衰竭预防剂
CN101095457B (zh) * 2007-06-23 2010-04-07 临夏州华安生物制品有限责任公司 酸水解酪蛋白的生产方法
JP5750039B2 (ja) * 2008-03-26 2015-07-15 グランビア ニュートリショナルズ （アイルランド） リミテッド ロイシンリッチペプチド組成物および単離法
CN101768209B (zh) * 2009-01-05 2011-08-31 北京林业大学 具有高体内活性的降血压肽及其制备和纯化方法
CN101570568B (zh) * 2009-06-15 2012-05-30 东北农业大学 一种发酵乳中的ace抑制肽及其制备方法
CN102187935B (zh) * 2010-03-19 2012-12-19 江南大学 一种制备酪蛋白磷酸肽与ace抑制肽的方法
CN102399261B (zh) * 2010-09-07 2014-06-25 任发政 具有血管紧张素转化酶c-端选择性抑制活性的三肽及其应用和组合物
US20120115786A1 (en) * 2010-11-09 2012-05-10 Calpis Co., Ltd. Agent for reducing risk in onset of disease ascribable to non-dipper circadian rhythm of blood pressure
US9523109B2 (en) 2011-06-24 2016-12-20 Calpis Co., Ltd. Method for enzymatically preparing peptides for use in improvement of brain function
JP5718741B2 (ja) * 2011-06-24 2015-05-13 カルピス株式会社 脳機能改善用ペプチドの酵素的製造方法
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CN103215332A (zh) * 2013-04-16 2013-07-24 陕西科技大学 一种分步酶解羊乳酪蛋白制备ace抑制肽的方法
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ES2544153B1 (es) * 2014-02-24 2016-06-06 Ntd Labs, S.L. Uso de un hidrolizado de caseína como agente antiviral
JP6251667B2 (ja) 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法
CN105693817B (zh) 2014-11-27 2020-06-05 西北大学 一类三肽化合物及其制备方法与应用
JP6005202B2 (ja) * 2015-03-19 2016-10-12 アサヒグループホールディングス株式会社 脳機能改善用ペプチドの酵素的製造方法
JP6625366B2 (ja) * 2015-08-05 2019-12-25 学校法人北里研究所 豚肉の熟成中に生成する生理活性ペプチドを含む血圧降下剤及び食品、並びにペプチドを指標とする豚肉の熟成評価法
CN106119325A (zh) * 2016-06-23 2016-11-16 哈尔滨商业大学 一种具有增加肌肉含量和力量作用的酪蛋白水解物的制备方法
CN107375897A (zh) * 2017-08-15 2017-11-24 普维食品发展（上海）有限公司 一种辅助降血压的组合物及其用途
CN107348511B (zh) * 2017-08-21 2018-04-06 东方红（通化）生物医药股份有限公司 一种具有辅助降血压作用的西洋参/人参提取物的发酵提取方法
CN108003231A (zh) * 2017-11-13 2018-05-08 江苏大学 一种降低小分子肽中游离氨基酸含量的方法
CN108588156A (zh) * 2018-04-24 2018-09-28 浙江大学 一种水牛乳酪蛋白抗氧化活性肽的制备方法
CN112041328B (zh) * 2018-04-26 2024-06-21 志瑞亚新药工业株式会社 二肽和含有该二肽的药物组合物
CN110467649A (zh) * 2019-09-12 2019-11-19 浙江省农业科学院 一种抑制血管紧张素转换酶活性的多肽qeip及其应用
CN113321719B (zh) * 2021-05-20 2022-03-18 澳优乳业（中国）有限公司 一种寡肽及其制备方法与应用
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Also Published As

Publication number Publication date
EA200600349A1 (ru) 2006-08-25
EP1669463B1 (en) 2008-10-15
HK1093991A1 (en) 2007-03-16
TW200507869A (en) 2005-03-01
CN1832958A (zh) 2006-09-13
BRPI0413242A (pt) 2006-10-03
PT1661909E (pt) 2009-12-17
TWI349676B (en) 2011-10-01
EP1661909A4 (en) 2006-08-30
WO2005012334A1 (ja) 2005-02-10
CN1833031A (zh) 2006-09-13
KR20060120567A (ko) 2006-11-27
KR101115560B1 (ko) 2012-03-13
JP5341300B2 (ja) 2013-11-13
CA2532537A1 (en) 2005-02-10
NZ545340A (en) 2010-04-30
AU2004261855B2 (en) 2010-09-16
US20070299014A1 (en) 2007-12-27
KR101115557B1 (ko) 2012-03-13
JPWO2005012334A1 (ja) 2008-01-17
AU2004261855A1 (en) 2005-02-10
AU2004261522A1 (en) 2005-02-10
CN101381401A (zh) 2009-03-11
TWI341866B (en) 2011-05-11
WO2005012334A8 (ja) 2005-06-30
JPWO2005012542A1 (ja) 2007-09-27
BRPI0413238A (pt) 2006-10-03
EA010098B1 (ru) 2008-06-30
ES2331312T3 (es) 2009-12-29
MXPA06000878A (es) 2006-03-30
MXPA06000879A (es) 2006-03-30
KR20060118395A (ko) 2006-11-23
KR20110039379A (ko) 2011-04-15
PT1669463E (pt) 2009-01-23
HK1094008A1 (en) 2007-03-16
NZ545341A (en) 2009-06-26
AU2004261522B2 (en) 2010-09-16
TW200505471A (en) 2005-02-16
US8580557B2 (en) 2013-11-12
NO20060994L (no) 2006-02-28
DE602004017202D1 (de) 2008-11-27
US20110082281A1 (en) 2011-04-07
EP1661909A1 (en) 2006-05-31
ZA200601739B (en) 2007-05-30
CA2546497A1 (en) 2005-02-10
DE602004023210D1 (de) 2009-10-29
EA011570B1 (ru) 2009-04-28
KR101174299B1 (ko) 2012-08-16
DK1661909T3 (da) 2010-01-18
EP1669463A4 (en) 2006-08-23
UA87278C2 (ru) 2009-07-10
ATE411035T1 (de) 2008-10-15
EA200600352A1 (ru) 2006-08-25
EP1669463A1 (en) 2006-06-14
NO20060995L (no) 2006-02-28
CN100439393C (zh) 2008-12-03
EP1661909B1 (en) 2009-09-16
ZA200601746B (en) 2007-05-30
CN100398661C (zh) 2008-07-02
JP2011102327A (ja) 2011-05-26
WO2005012542A1 (ja) 2005-02-10
UA89616C2 (ru) 2010-02-25
US20070122451A1 (en) 2007-05-31
JP4669396B2 (ja) 2011-04-13
ES2313067T3 (es) 2009-03-01
ATE442855T1 (de) 2009-10-15
PL1669463T3 (pl) 2009-02-27

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