CN109464341A - A kind of health care composition - Google Patents
A kind of health care composition Download PDFInfo
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- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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Abstract
The present invention discloses a kind of health care composition, composed of the following components: thickener, surfactant, moisturizer, moisturizing ingredient, shrubby sophora extract, shaddock ped extract, anisic acid, menthol, acidity-basicity regulator, surplus are pure water.Health care composition of the present invention, ingredient are natural component, any harmful substance of non-impurity-doped, not only effectively reinforce greasy skin, sterilizing and itch-relieving, alleviate the basic functions such as itch, and safety coefficient is high, nonirritant effect, and physiological security is good.
Description
Technical field
The present invention relates to human physiology nursing materials technical field more particularly to a kind of health care compositions.
Background technique
Since long-time is in the environment of humid, bacterium easy to breed at human private, to generate red and swollen, itch
Or inflammation, vaginal flora is unbalance and microecological balance problem；These drastically influence the quality of the life of women.Vagina is from life
Said in angle of science be one closure body cavity, endoparasitism many bacteriums.Since the deep of vagina is almost without air, institute
With bacterial parasite based on oxygen oxygen bacterium or amphimicrobian bacterial strain.1960's Morris is studied from 219 normal child-bearing period woman
Staphylococcus, streptococcus, Escherichia coli, baseball bacillus and the enterococcus isolated in woman's vaginal discharge.It is now fixed to determine
Planting mainly has bacterium, fungi, protozoon and virus in the micropopulation in normal vagina, their main perch are in the side of vagina surrounding
In wall mucous membrane gauffer, followed by fornix, partially in uterine neck.
With the further investigation to gynecological disease, researchers have found that vulvovaginitis all has with the growth of harmful bacteria
It closes, because a little, maintenance microecological balance prevents harmful bacteria from playing an important role in the breeding of privates to maintenance vaginal health.
Currently, effectively controlling vagina harmful microbe, the methods of chemical bactericide, antibiotic are relied primarily on.In bed treatment, often make
With antibiotic and phosphoramidite chemical fungicide.Although having preferable therapeutic effect, long-time service can cause vaginal flora to lose
It adjusts, it will lead to the product of bacterial drug resistance, to need that it is available finally to become no medicine using bigger dosage.
The task of top priority solves the problems, such as privates drug resistance and normal flora imbalance, find it is natural, efficient it is antibacterial will yes
End is come the main trend researched and developed.This research passes through the compounding of bacteriostatic agent and auxiliary antipathogenic composition from natural bacteriostatic agent
Addition, to reach to the safe and effective fungistatic effect of privates pathogenic bacteria, and is applied in feminine care liquid product.
Summary of the invention
In conclusion the present invention is it is necessary to provide a kind of health care composition, in greasy skin, sterilizing and itch-relieving, clear
There is preferable resultant effect in the performances such as clean.
In addition, the present invention there is a need to provide a kind of preparation method of above-mentioned health care composition.
A kind of health care composition, consists of the following components in percentage by weight:
Thickener 1.5%-2.5%；
Surfactant 28%-50%；
Moisturizer 5%-10%；
Moisturizing ingredient 0.3%-1.0%；
Shrubby sophora extract 0.1-0.2%；
Shaddock ped extract 0.15-0.6%；
Anisic acid 0.2-0.45%；
Menthol 0.1%-0.4%；
Acidity-basicity regulator 0.25%-2.0%；
Surplus is pure water.
Wherein it is preferred to which the health care composition, consists of the following components in percentage by weight:
Thickener 1.8%-2.3%；
Surfactant 38%-50%；
Moisturizer 5%-8%；
Moisturizing ingredient 0.3%-0.45%；
Shrubby sophora extract 0.1-0.2%；
Shaddock ped extract 0.15-0.3%；
Anisic acid 0.2-0.35%；
Menthol 0.2%-0.35%；
Acidity-basicity regulator 1.25%-1.8%；
Surplus is pure water.
Wherein, the thickener is the mixture of Arabic gum natural gum and xanthan gum, the Arabic gum natural gum and xanthan
The mass ratio of glue is 5.5:4.5.
Wherein, the surfactant is the mixture of cocoyl apple amino acid sodium and decyl glucoside, cocounut oil
Acyl group apple amino acid sodium accounts for the 30-35% of the health care composition, and decyl glucoside accounts for the health care combination
The 8-15% of object.
Wherein, the moisturizer is the mixed of Xylitol-based glucoside, anhydro xylitol, xylitol, glucose and pure water
Close object, the Xylitol-based glucoside, anhydro xylitol, xylitol, glucose and pure water mass ratio be (35-50):
(24-34): (5-15): (0-5): (15-17).
Wherein, the moisturizing ingredient is evening primrose oil and Butyrospermum parkii fruit rouge, and evening primrose oil accounts for the health care combination
0.2-0.3%, the Butyrospermum parkii fruit rouge of object account for the 0.2%-0.3% of the health care composition.
Wherein, the acidity-basicity regulator is lactic acid solution, and preferably the concentration of lactic acid solution is 1%.
A kind of production method of health care composition as described above, comprising the following steps:
1) it stocks up by the parts by weight, at room temperature adds moisturizer, shrubby sophora extract, moisturizing ingredient and thickener
Enter in pure water, is stirred with the speed that rotary speed is 30~50r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, is stirred in the speed of revolving speed 30-50r/min
5min makes mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol, which adds 50-60 DEG C of decyl glucoside, to be continued to stir, with
30~50r/min of revolving speed stirs 5min, makes mixed liquor at uniform emulsus lotion；
4) lactic acid is dissolved in pure water, is added in the emulsus lotion of step 3), add surplus pure water, starting is equal
Matter device, with revolving speed 2800r/min, homogeneous 10min.
Do selection of land, the production method of the health care composition, comprising the following steps:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with the speed that rotary speed is 30~50r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, is stirred in the speed of revolving speed 30-50r/min
5min makes mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid, menthol is added, adds decyl glucoside, continues to stir at 50-60 DEG C
It mixes, with 30~50r/min of revolving speed, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min.
Composition of the present invention is used in KMS health formula, with greasy skin, sterilization, cleaning and other effects.
Compared with the prior art, health care composition of the present invention, ingredient are natural component, and non-impurity-doped is any
Harmful substance not only effectively reinforces greasy skin, sterilizing and itch-relieving, alleviates the basic functions such as itch, but also safety coefficient is high, stingless
Swash property effect, and physiological security is good.
Specific embodiment
Structure material of the present invention, preparation method and applications are done below with reference to some specific embodiments and are further retouched
It states.Specific embodiment is that present invention be described in more detail, non-limiting protection scope of the present invention.
The substance source that the present invention is implemented is as follows:
Thickener is the mixture of Arabic gum natural gum and xanthan gum, the mass ratio of the Arabic gum natural gum and xanthan gum
For 5.5:4.5；
Cocoyl apple amino acid sodium comes from Shenzhen Ying Bote foreign trade Co., Ltd；
Moisturizer, for the mixture of Xylitol-based glucoside, anhydro xylitol, xylitol, glucose and pure water, it is described
Xylitol-based glucoside, anhydro xylitol, xylitol, glucose and pure water mass ratio be 50:30:10:5:15；
Evening primrose oil comes from Spain's evening primrose oil [Evening Primrose Oil]；Brand: Arabica/ I compare
Card
Butyrospermum parkii fruit rouge refines shea butter, comes from Cargill Inc.
Lactic acid solution comes from Dutch Aksu company,
Shrubby sophora extract comes from Shaanxi Teng Mai biotechnology Co., Ltd；
Shaddock ped extract comes from Xi'an Ai Nuo medical sci-tech Co., Ltd.
Embodiment 1
It stocks up by quality formula rate described in table 1, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 50r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 50r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 50r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
Embodiment 2
It stocks up by quality formula rate described in table 1, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 30r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 30r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 30r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
Embodiment 3
It stocks up by quality formula rate described in table 1, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 40r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 40r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 40r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
Embodiment 4
It stocks up by quality formula rate described in table 1, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 30r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 50r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 40r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
The formula table of 1 embodiment 1-4 of table
Comparative example 1
It stocks up by quality formula rate described in table 2, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 50r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 50r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 50r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
Comparative example 2
It stocks up by quality formula rate described in table 2, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 30r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 30r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 30r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
Comparative example 3
It stocks up by quality formula rate described in table 2, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 40r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 40r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 40r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
Comparative example 4
It stocks up by quality formula rate described in table 2, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 30r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 50r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 40r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
The formula table of 2 comparative example 1-4 of table
Bacteriostasis rate measurement is carried out respectively to conditioning liquid made from embodiment 1-4 and comparative example 1-4, it is attached by GB15979-2002
It records C4 stripping property and resists the test of (suppression) bacterium product bacteriostasis property, conditioning liquid is acted on into 2min, test result is shown in Table 3.
The conditioning liquid bacteriostasis rate of 3. various concentration shaddock ped extract of table, unit %
The results show that antibacterial effect of the conditioning liquid fungistatic effect better than conditioning liquid made from comparative example 1-4 is made in embodiment 1-4
Fruit.
The ingredient of skin care solution of the invention is natural component, and any harmful substance of non-impurity-doped is not only effectively reinforced
Greasy skin, sterilizing and itch-relieving alleviate the basic functions such as itch, and safety coefficient is high, nonirritant effect, and physiological security is good
It is good.
Comparative example 5
It stocks up by quality formula rate described in embodiment 1, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 20r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 20r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 20r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
Comparative example 6
It stocks up by quality formula rate as described in example 2, health care composition is then prepared as follows:
1) it stocks up by the parts by weight, at room temperature mentions moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, kuh-seng
It takes object, thickener to be added in pure water, is stirred with rotary speed for the speed of 60r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 60r/min,
Make mixed liquor that gel state be presented,
3) shaddock ped extract, anisic acid is added, menthol adds decyl glucan glycosides, continues to stir at 50-60 DEG C
It mixes, with revolving speed 60r/min, stirs 5min, make mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min,
Obtain health care composition.
Health care composition stability is made to embodiment 1-2 and comparative example 5-6 to detect, testing result is listed in table
In 4.
Heat-resistant stability
2 bottles of samples are randomly selected, is placed in the insulating box for being pre-adjusted (45 ± 2) DEG C, is taken out after for 24 hours, recovery room
Wen Hou, 2 bottles of samples are poured into respectively in two colorimetric cylinders, and liquid level is made to be no less than 50mm, compared with stoste range estimation.
Cold-resistant stability
2 bottles of samples are randomly selected, are placed in the refrigerator or high-low temperature test chamber for being pre-adjusted (- 15 ± 2) DEG C, through for 24 hours
After take out, restore room temperature after, 2 bottles of samples are poured into respectively in two colorimetric cylinders, so that liquid level is no less than 50mm, with stoste estimate
Compare.
Sense index and physical and chemical index
4 embodiment 1-2 of table is compared with the stability result of comparative example 5-6
| Embodiment 1 | Embodiment 2 | Comparative example 5 | Comparative example 6 | |
| Heat-resistant stability | Without significant change | Without significant change | Floccule is arranged at bottom | Without significant change |
| Cold-resistant stability | Without significant change | Without significant change | There is gelatin phenomenon | There is lamination |
The above description is only an embodiment of the present invention, is not intended to limit the scope of the invention, all to utilize this hair
Equivalent structure or equivalent flow shift made by bright description is applied directly or indirectly in other relevant technology necks
Domain is included within the scope of the present invention.
Claims (9)
1. a kind of health care composition, consists of the following components in percentage by weight:
Thickener 1.5%-2.5%；
Surfactant 28%-50%；
Moisturizer 5%-10%；
Moisturizing ingredient 0.3%-1.0%；
Shrubby sophora extract 0.1-0.2%；
Shaddock ped extract 0.15-0.6%；
Anisic acid 0.2-0.45%；
Menthol 0.1%-0.4%；
Acidity-basicity regulator 0.25%-2.0%；
Surplus is pure water.
2. health care composition as described in claim 1, it is characterised in that: consist of the following components in percentage by weight:
Thickener 1.8%-2.3%；
Surfactant 38%-50%；
Moisturizer 5%-8%；
Moisturizing ingredient 0.3%-0.45%；
Shrubby sophora extract 0.1-0.2%；
Shaddock ped extract 0.15-0.3%；
Anisic acid 0.2-0.35%；
Menthol 0.2%-0.35%；
Acidity-basicity regulator 1.25%-1.8%；
Surplus is pure water.
3. health care composition as claimed in claim 1 or 2, it is characterised in that:
The thickener is the mixture of Arabic gum natural gum and xanthan gum, the mass ratio of the Arabic gum natural gum and xanthan gum
For 5.5:4.5.
4. health care composition as claimed in claim 1 or 2, it is characterised in that:
The surfactant is the mixture of cocoyl apple amino acid sodium and decyl glucoside, cocoyl apple ammonia
Base acid sodium accounts for the 30-35% of the health care composition, and decyl glucoside accounts for the 8-15% of the health care composition.
5. health care composition as claimed in claim 1 or 2, it is characterised in that:
The moisturizer is the mixture of Xylitol-based glucoside, anhydro xylitol, xylitol, glucose and pure water, described
Xylitol-based glucoside, anhydro xylitol, xylitol, glucose and pure water mass ratio be (35-50): (24-34): (5-
15): (0-5): (15-17).
6. health care composition as claimed in claim 1 or 2, it is characterised in that:
The moisturizing ingredient is evening primrose oil and Butyrospermum parkii fruit rouge, and evening primrose oil accounts for the 0.15- of the health care composition
0.3%, Butyrospermum parkii fruit rouge accounts for the 0.15%-0.3% of the health care composition.
7. health care composition as claimed in claim 1 or 2, it is characterised in that:
The acidity-basicity regulator is lactic acid solution.
8. a kind of production method of such as described in any item health care compositions of claim 1-7, comprising the following steps:
1) it stocks up, moisturizer, shrubby sophora extract, moisturizing ingredient and thickener is added at room temperature pure by the parts by weight
In water purification, is stirred with the speed that rotary speed is 30~50r/min, stir 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 30-50r/min, makes
Gel state is presented in mixed liquor,
3) shaddock ped extract, anisic acid is added, menthol, which adds 50-60 DEG C of decyl glucoside, to be continued to stir, with revolving speed
30~50r/min stirs 5min, makes mixed liquor at uniform emulsus lotion；
4) lactic acid is dissolved in pure water, is added in the emulsus lotion of step 3), add surplus pure water, start homogeneous
Device, with revolving speed 2800r/min, homogeneous 10min.
9. a kind of production method of such as described in any item health care compositions of claim 1-7, comprising the following steps:
1) stock up by the parts by weight, at room temperature by moisturizer, evening primrose oil, Butyrospermum parkii fruit rouge, shrubby sophora extract,
Thickener is added in pure water, is stirred with the speed that rotary speed is 30~50r/min, stirs 10min；
2) cocoyl apple amino acid sodium is added, stirs while adding, stirs 5min in the speed of revolving speed 30-50r/min, makes
Gel state is presented in mixed liquor,
3) shaddock ped extract, anisic acid, menthol is added, adds decyl glucoside, continues to stir at 50-60 DEG C,
With 30~50r/min of revolving speed, 5min is stirred, makes mixed liquor at uniform emulsus lotion；
4) lactic acid solution is added, adds pure water, starts homogenizer, with revolving speed 2800r/min, homogeneous 10min.
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