CN106236835A - A kind of plants essential oil spray and its preparation method and application - Google Patents
A kind of plants essential oil spray and its preparation method and application Download PDFInfo
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Abstract
The present invention provides a kind of plants essential oil spray and its preparation method and application, and this spray includes plants essential oil and adjuvant, and by weight, described plants essential oil includes: the Oleum Cinnamomi of 15 parts, the Oleum Ocimi Gratissimi of 15 parts and the Oleum Terebinthinae of 15 parts.The present invention utilizes natural plants essential oil, and with beta-cyclodextrin for embedding base material, in conjunction with the excellent Biofunctional of chitosan with by membrane property, preparation is for treating bacillary and that Fungal Skin is scorching spray.Raw material sources are natural, low cost, and the spray good antimicrobial effect of preparation, and processing technique is simple, and low cost has no side effect substantially, and the spray of preparation has good therapeutic effect.
Description
Technical field
The present invention relates to a kind of plants essential oil spray and its preparation method and application, belong to medical spray technical field.
Background technology
The development of skin treating external dressing is very fast, but currently also has some limitations, especially anti-
On microbial inoculum selects, easily inducing body to produce drug resistance due to antibiotic, the development of antibacterial agent becomes focus in recent years.
The natural antimicrobial substances such as chitosan are primarily adapted for use in the situation that gradient of infection is relatively low；Currently used other antibacterial such as nanometer
Though the antibacterial abilities such as silver, silver sulfadiazine TiO2 are relatively strong, but all there is certain cytotoxicity, although use polymer embedding etc.
Slow release measure can reduce its cytotoxicity to a certain extent, but improves preparation method the most further, makes the antibacterial can be according to wound
Face inflammatory conditions is controlled release, and researches and develops novel low toxicity broad-spectrum antiseptic reagent, is all that antiseptic dressing research from now on is exerted
The direction of power.
Dermatosis is a variety of, the most bacillary in the majority with dermatomycosis, and treats based on external application emulsifiable paste or spray,
Wherein many to write hormones with chemosynthesis class medicine and one in the majority for effective ingredient, and these antibioticses and hormone medicine are treated not
Thoroughly, and be easy to allow the pathogenic microorganism of patient produce drug resistance.At present with miconazole fluconazol clotrimazole on clinical treatment
It is main Deng antifungal agent.Due to the irrational use of antibiotic, analysis of clinic pathogenic microorganism to the sensitivity of existing antifungal drug with
Before compare and be decreased obviously, and the trend that its drug resistance makes further progress.Compared with conventional antifungal medicine, plant extract is lived
Property composition and compound treatment vaginitis have that antifungic action is strong, stable curative effect, toxicity are low is difficult to the advantages such as drug resistance.
Now yet there are no and utilize plants essential oil compound recipe spray in dermatosis disease treatment sides such as bacillary and Fungal Skin are scorching
The application report in face.
Summary of the invention
Present invention solves the technical problem that and be, utilize three kinds of plants essential oils, be i.e. Oleum Cinnamomi, Oleum Ocimi Gratissimi and terebinthine
The treatment of the diseases such as antibacterial characteristics, is applied at scytitis, and the most bacillary and Fungal Skin is scorching.
The technical scheme is that, it is provided that a kind of plants essential oil spray, including plants essential oil and adjuvant, by weight,
Described plants essential oil includes: the Oleum Cinnamomi of 1-5 part, the Oleum Ocimi Gratissimi of 1-5 part and the Oleum Terebinthinae of 1-5 part.
Further, described spray also includes the Mentholum of 0.05-0.15 weight portion.
Further, described spray also includes the tea polyphenols of 0.01-0.03 weight portion.
Further, described adjuvant includes chitosan and the beta-schardinger dextrin-of 1-10 weight portion of 0.1-1 weight portion.
Further, described adjuvant includes the glycerol of 1-3 weight portion.
Further, described adjuvant also includes the Polyethylene Glycol of 0.1-0.3 weight portion.
Further, described adjuvant also includes the lactic acid of 0.01-0.1 weight portion.
The present invention provides the preparation method of a kind of plants essential oil spray further, comprises the following steps:
(1) by weight, by the Oleum Cinnamomi of 1-5 part, the Oleum Ocimi Gratissimi of 1-5 part, the Oleum Terebinthinae of 1-5 part, 1-3 part sweet
Oil and water make mixed liquor A；Mixed liquor A being uniformly mixed, add the Polyethylene Glycol of 0.1-0.3 part, stirring is to not stratified
The tea polyphenols of rear interpolation 0.01-0.03 part, obtains mixed liquid B；By chitosan and the beta-schardinger dextrin-dispersion of 1-10 part of 0.1-1 part
Yu Shuizhong, obtains mixed liquor C；
(2) mixed liquid B is mixed and stirred for not stratified with mixed liquor C, obtains mixed liquor D；
(4) in mixed liquor D, add the Mentholum of 0.05-0.15 weight portion, obtain mixed liquor E；
(5) with the pH of the lactic acid regulation mixed liquor E of 0.01-0.1 weight portion, plants essential oil spray is obtained.
Further, described Polyethylene Glycol is PEG-400.
The present invention further provides the application on preparation treatment dermatosis treating medicine of the described spray.
Oleum Cinnamomi has the special fragrance of Cortex Cinnamomi, has obvious fungistatic effect to antibacterial, yeast and fungus, especially anti-true
Bacterium effect is the best.Oleum Cinnamomi is conducive to the growth and breeding of probiotics lactic acid bacteria simultaneously, and then the life of beneficially vagina lactic acid bacteria
Long, maintain acid vagina environment, improve microecology in vaginas balance, promote colpitic healing.Various skin tinea bacterium is had simultaneously
Significantly inhibitory action.
Oleum Ocimi Gratissimi its be mainly composed of eugenol, also containing linalool, ocimene etc., there is bacteria growing inhibiting, promote
Enter the pharmacological actions such as damaged skin normal healing, always treat mainly planting of a lot of bacterial Related Skin Diseases and inflammation
Thing quintessence oil.
Oleum Terebinthinae has the multiple efficacies such as anti-inflammatory analgetic, antibacterial parasite killing, mixes with Oleum Cinnamomi and Oleum Ocimi Gratissimi, energy simultaneously
It is obviously promoted both fungistatic effects.
Lactic acid has the strongest anti-corrosive fresh-keeping effect and hygroscopicity, has regulation pH value, antibacterial, holding film color and luster and humidity etc.
Effect, in lactic acid also helps induction woman vagina simultaneously, the growth of beneficial microbe lactic acid bacteria, causes probiotic bacteria to become advantage
Bacterial strain, thus suppression causes the growth and breeding of the harmful bacteria such as staphylococcus aureus, streptococcus bacterium.
Tea polyphenols has the strongest antioxidation, and its oxidation resistance is the 4-6 of synthetic antioxidant BHT, BHA
Times, 6-7 times of VE, 5-10 times of VC, and consumption is few, and without the potential toxic and side effects of synthetic；Can effectively prevent plants essential oil
Corruption, and abnormal flavour can be eliminated.
Mentholum has the effect of reducing swelling and alleviating pain, antiphlogistic antibacterial.Simultaneously refrigerant skin moistening specific to Herba Menthae and fragrance pleasant
Abnormal smells from the patient is covered up and improved some has abnormal flavour, it is also possible to eliminate twinge and sense of discomfort phenomenon that patient is caused by low ph conditions.
Cycloheptaamylose has the functions such as some material antioxidation of protection, anti-light, heat resistanceheat resistant, volatilization prevention and immobilization.
Chitosan has excellent biological functionality and the compatibility, blood compatibility, safety, microbic resolvability.Tool
There are the functions such as good moisture absorption, moisturizing, conditioning, the growth and breeding of some funguses, antibacterial and virus can be suppressed.
Plants essential oil is applied in the spray for the treatment of dermatitis disease by the present invention, has widened the antibacterial or choosing of Fungicidal substance
Select scope, obtained that there is the most antibacterial or spray of bactericidal property, achieved the high value added utilization of plant extract component
While, theory and the method with reference value is provided for the research of novel spray.
The beneficial effects of the present invention is: utilize natural plants essential oil, with cycloheptaamylose for embedding base material, in conjunction with shell
The excellent Biofunctional of polysaccharide and by membrane property, preparation is for treating bacillary and that Fungal Skin is scorching spray.Raw material comes
Source is natural, low cost, and the spray good antimicrobial effect of preparation, and processing technique is simple, and low cost has no side effect substantially, preparation
Spray there is good therapeutic effect.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1g, 0.1g chitosan is then added；
(2) mixed with 50g water Oleum Cinnamomi (1g) respectively, Oleum Ocimi Gratissimi (1g), Oleum Terebinthinae (1g) and glycerol (2g) stirring
Closing uniformly, add 0.1g PEG400 simultaneously, stirring adds tea polyphenols 0.01g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.05g；
(5) lactic acid of 0.01g is added after being stirred by the mixture in step (4).
Embodiment 2
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1g, 0.1g chitosan is then added；
(2) stir with Oleum Cinnamomi (5g), Oleum Ocimi Gratissimi (5g), Oleum Terebinthinae (5g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.5g PEG400 simultaneously, and stirring adds tea polyphenols 0.02g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.1g；
(5) lactic acid of 0.05g is added after being stirred by the mixture in step (4).
Embodiment 3
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1g, 0.1g chitosan is then added；
(2) stir with Oleum Cinnamomi (3g), Oleum Ocimi Gratissimi (3g), Oleum Terebinthinae (3g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.3g PEG400 simultaneously, and stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.1g is added after being stirred by the mixture in step (4).
Embodiment 4
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-5g, 0.5g chitosan is then added；
(2) stir with Oleum Cinnamomi (1g), Oleum Ocimi Gratissimi (1g), Oleum Terebinthinae (1g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.1g PEG400 simultaneously, and stirring adds tea polyphenols 0.01g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.05g；
(5) lactic acid of 0.01g is added after being stirred by the mixture in step (4).
Embodiment 5
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-5g, 0.5g chitosan is then added；
(2) stir with Oleum Cinnamomi (5g), Oleum Ocimi Gratissimi (5g), Oleum Terebinthinae (5g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.2g PEG400 simultaneously, and stirring adds tea polyphenols 0.02g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.1g；
(5) lactic acid of 0.05g is added after being stirred by the mixture in step (4).
Embodiment 6
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-5g, 0.5g chitosan is then added；
(2) stir with Oleum Cinnamomi (3g), Oleum Ocimi Gratissimi (3g), Oleum Terebinthinae (3g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.3g PEG400 simultaneously, and stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.1g is added after being stirred by the mixture in step (4).
Embodiment 7
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-10g, 1.0g chitosan is then added；
(2) stir with Oleum Cinnamomi (1g), Oleum Ocimi Gratissimi (1g), Oleum Terebinthinae (1g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.1g PEG400 simultaneously, and stirring adds tea polyphenols 0.01g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.05g；
(5) lactic acid of 0.01g is added after being stirred by the mixture in step (4).
Embodiment 8
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-10g, 1.0g chitosan is then added；
(2) stir with Oleum Cinnamomi (5g), Oleum Ocimi Gratissimi (5g), Oleum Terebinthinae (5g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.2g PEG400 simultaneously, and stirring adds tea polyphenols 0.02g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.1g；
(5) lactic acid of 0.05g is added after being stirred by the mixture in step (4).
Embodiment 9
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-10g, 1.0g chitosan is then added；
(2) stir with Oleum Cinnamomi (3g), Oleum Ocimi Gratissimi (3g), Oleum Terebinthinae (3g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.3g PEG400 simultaneously, and stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.1g is added after being stirred by the mixture in step (4).
Embodiment 10
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1.0g, 1.0g chitosan is then added；
(2) stir with Oleum Cinnamomi (1g), Oleum Ocimi Gratissimi (1g), Oleum Terebinthinae (1g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.1g PEG400 simultaneously, and stirring adds tea polyphenols 0.01g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.05g；
(5) lactic acid of 0.01g is added after being stirred by the mixture in step (4).
Embodiment 11
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1.0g, 1.0g chitosan is then added；
(2) stir with Oleum Cinnamomi (5g), Oleum Ocimi Gratissimi (5g), Oleum Terebinthinae (5g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.2g PEG400 simultaneously, and stirring adds tea polyphenols 0.02g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.1g；
(5) lactic acid of 0.05g is added after being stirred by the mixture in step (4).
Embodiment 12
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1.0g, 1.0g chitosan is then added；
(2) stir with Oleum Cinnamomi (3g), Oleum Ocimi Gratissimi (3g), Oleum Terebinthinae (3g) and glycerol (2g) respectively with 50g water
Mix homogeneously, adds 0.3g PEG400 simultaneously, and stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.03g is added after being stirred by the mixture in step (4).
Embodiment 13
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1.0g, 1.0g chitosan is then added；
(2) it is uniformly mixed with Oleum Terebinthinae (3g) and glycerol (2g) respectively with 50g water, adds the poly-second of 0.3g two simultaneously
Alcohol 400, stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.03g is added after being stirred by the mixture in step (4).
Embodiment 14
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1.0g, 1.0g chitosan is then added；
(2) with 50g water respectively with Oleum Cinnamomi (3g) and glycerol (2g) be uniformly mixed, simultaneously add the poly-second of 0.3g
Glycol 400, stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.03g is added after being stirred by the mixture in step (4).
Embodiment 15
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1.0g, 1.0g chitosan is then added；
(2) it is uniformly mixed with Oleum Ocimi Gratissimi (3g) and glycerol (2g) respectively with 50g water, adds 0.3g simultaneously and gather
Ethylene glycol 400, stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.03g is added after being stirred by the mixture in step (4).
Embodiment 16
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1.0g, 1.0g chitosan is then added；
(2) it is uniformly mixed with Oleum Cinnamomi (3g), Oleum Terebinthinae (3g) and glycerol (2g) respectively with 50g water, adds simultaneously
Adding 0.3g PEG400, stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.03g is added after being stirred by the mixture in step (4).
Embodiment 17
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1.0g, 1.0g chitosan is then added；
(2) it is uniformly mixed with Oleum Ocimi Gratissimi (3g), Oleum Terebinthinae (3g) and glycerol (2g) respectively with 50g water, with
Shi Tianjia 0.3g PEG400, stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.03g is added after being stirred by the mixture in step (4).
Embodiment 18
The present embodiment provides a kind of plants essential oil spray, specifically comprises the following steps that
(1) with 50g water dissolution beta-schardinger dextrin-1.0g, 1.0g chitosan is then added；
(2) it is uniformly mixed with Oleum Cinnamomi (3g), Oleum Ocimi Gratissimi (3g) and glycerol (2g) respectively with 50g water, with
Shi Tianjia 0.3g PEG400, stirring adds tea polyphenols 0.03g after not stratified；
(3) by step (1) and step (2) solution mix, and constantly stir not stratified till；
(4) solution in step (3) is added Mentholum 0.15g；
(5) lactic acid of 0.03g is added after being stirred by the mixture in step (4).
Experimental data from table 1:
(1) data of the bacteriostatic test of the spray, from embodiment 1-12 prepared, three kinds of plant essential oil component (Cortex Cinnamomis
Oil, Oleum Ocimi Gratissimi, Oleum Terebinthinae) interpolation and the control of concentration, be greatly improved its fungistatic effect, be conducive to its popularization
Application；
(2) data of the bacteriostatic test of the spray, from embodiment 1-12 prepared, the interpolation of chitosan strengthens further
The fungistatic effect of plants essential oil spray, and it be ensure that the long-lasting of fungistatic effect by membrane property.AddO-on therapy is all plant
Source property, safety is high.
(3) data of the bacteriostatic test of the spray, from embodiment 12-18 prepared, Oleum Cinnamomi, Oleum Ocimi Gratissimi, pine
The fungistatic effect of the single interpolation of fuel-economizing is less than Oleum Cinnamomi+Oleum Terebinthinae, Oleum Ocimi Gratissimi+terebinthine fungistatic effect, more below meat
Cassia oil+Oleum Ocimi Gratissimi+terebinthine fungistatic effect.
(4) data of the bacteriostatic test of the spray, from embodiment 1-18 prepared, three kinds of quintessence oils can be the most collaborative,
Promote antibacterial, serve the effect that the most collaborative promotion is antibacterial.
The antibacterial data of table 1 embodiments of the invention 1-18 are as follows:
| Antibacterial circle diameter (mm) | Escherichia coli | Staphylococcus aureus | Candida albicans |
| Embodiment 1 | 15.0±1.33 | 16.8±1.44 | 15.8±1.25 |
| Embodiment 2 | 20.5±1.48 | 23.1±2.03 | 21.3±2.11 |
| Embodiment 3 | 18.7±1.54 | 20.6±1.89 | 19.7±1.56 |
| Embodiment 4 | 16.5±1.54 | 17.2±1.78 | 16.3±1.88 |
| Embodiment 5 | 22.3±2.55 | 22.3±2.34 | 23.4±2.07 |
| Embodiment 6 | 21.6±1.87 | 21.4±1.83 | 21.7±2.68 |
| Embodiment 7 | 18.5±1.89 | 19.3±2.33 | 18.7±2.45 |
| Embodiment 8 | 24.3±2.66 | 25.2±2.37 | 25.3±2.12 |
| Embodiment 9 | 22.3±2.13 | 23.2±2.23 | 22.3±2.36 |
| Embodiment 10 | 17.5±1.99 | 18.2±2.03 | 19.3±2.28 |
| Embodiment 11 | 23.3±2.15 | 23.6±2.03 | 23.8±2.03 |
| Embodiment 12 | 20.6±2.56 | 21.5±1.93 | 22.6±1.87 |
| Embodiment 13 (loose) | 3.2±0.33 | 4.1±0.14 | 6.3±1.01 |
| Embodiment 14 (meat) | 9.8±1.11 | 12.0±1.25 | 11.8±1.33 |
| Embodiment 15 (fourth) | 8.7±0.87 | 9.8±0.87 | 9.7±1.05 |
| Embodiment 16 (meat+pine) | 16.3±1.42 | 18.7±1.44 | 19.8±1.76 |
| Embodiment 17 (pine+fourth) | 14.1±1.24 | 16.2±1.13 | 19.2±1.53 |
| Embodiment 18 (meat+fourth) | 18.9±1.55 | 22.0±1.37 | 15.9±1.22 |
Claims (10)
1. a plants essential oil spray, including plants essential oil and adjuvant, it is characterised in that by weight, described plants essential oil bag
Include: the Oleum Cinnamomi of 1-5 part, the Oleum Ocimi Gratissimi of 1-5 part and the Oleum Terebinthinae of 1-5 part.
2. spray as claimed in claim 1, it is characterised in that described spray also includes the Mentholum of 0.05-0.15 weight portion.
3. spray as claimed in claim 1, it is characterised in that described spray also includes the tea polyphenols of 0.01-0.03 weight portion.
4. spray as claimed in claim 1, it is characterised in that described adjuvant includes chitosan and the 1-10 of 0.1-1 weight portion
The beta-schardinger dextrin-of weight portion.
5. spray as claimed in claim 4, it is characterised in that described adjuvant includes the glycerol of 1-3 weight portion.
6. spray as claimed in claim 4, it is characterised in that described adjuvant also includes the Polyethylene Glycol of 0.1-0.3 weight portion.
7. spray as claimed in claim 4, it is characterised in that described adjuvant also includes the lactic acid of 0.01-0.1 weight portion.
8. the preparation method of a plants essential oil spray, it is characterised in that comprise the following steps:
(1) by weight, by the Oleum Cinnamomi of 1-5 part, the Oleum Ocimi Gratissimi of 1-5 part, the Oleum Terebinthinae of 1-5 part, the glycerol of 1-3 part
Mixed liquor A is made with water；Mixed liquor A is uniformly mixed, adds the Polyethylene Glycol of 0.1-0.3 part, after stirring is the most not stratified
Add the tea polyphenols of 0.01-0.03 part, obtain mixed liquid B；The chitosan of 0.1-1 part and the beta-schardinger dextrin-of 1-10 part are scattered in
In water, obtain mixed liquor C；
(2) mixed liquid B is mixed and stirred for not stratified with mixed liquor C, obtains mixed liquor D；
(4) in mixed liquor D, add the Mentholum of 0.05-0.15 weight portion, obtain mixed liquor E；
(5) with the pH of the lactic acid regulation mixed liquor E of 0.01-0.1 weight portion, plants essential oil spray is obtained.
9. preparation method as claimed in claim 8, it is characterised in that described Polyethylene Glycol is PEG-400.
10. the application on preparation treatment dermatosis treating medicine of the spray described in claim 1-7.
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| CN111956687A (en) * | 2020-07-09 | 2020-11-20 | 上海军慧医疗管理有限公司 | Bacteriostatic foot care solution containing plant essential oil and preparation method of foot care solution |
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| CN108925561A (en) * | 2018-08-08 | 2018-12-04 | 邯郸学院 | A kind of antibacterial sustained release agent and preparation method thereof |
| CN108925561B (en) * | 2018-08-08 | 2020-07-21 | 邯郸学院 | Antibacterial sustained-release agent and preparation method thereof |
| CN111956687A (en) * | 2020-07-09 | 2020-11-20 | 上海军慧医疗管理有限公司 | Bacteriostatic foot care solution containing plant essential oil and preparation method of foot care solution |
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