BRPI0818674A2 - Método para produção de anticorpos - Google Patents
Método para produção de anticorposInfo
- Publication number
- BRPI0818674A2 BRPI0818674A2 BRPI0818674-0A2A BRPI0818674A BRPI0818674A2 BR PI0818674 A2 BRPI0818674 A2 BR PI0818674A2 BR PI0818674 A BRPI0818674 A BR PI0818674A BR PI0818674 A2 BRPI0818674 A2 BR PI0818674A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibody production
- antibody
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-267384 | 2007-10-15 | ||
JP2007267384 | 2007-10-15 | ||
JP2008-103308 | 2008-04-11 | ||
JP2008103308 | 2008-04-11 | ||
PCT/JP2008/068588 WO2009051108A1 (ja) | 2007-10-15 | 2008-10-14 | 抗体の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0818674A2 true BRPI0818674A2 (pt) | 2014-10-14 |
BRPI0818674B1 BRPI0818674B1 (pt) | 2023-01-17 |
Family
ID=40567372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0818674-0A BRPI0818674B1 (pt) | 2007-10-15 | 2008-10-14 | Métodos para produção de um anticorpo inteiro ou de um fragmento do mesmo e para preparação de fármacos, bem como vetor recombinante |
Country Status (17)
Country | Link |
---|---|
US (2) | US9683027B2 (pt) |
EP (1) | EP2202307B2 (pt) |
JP (4) | JP4976502B2 (pt) |
KR (1) | KR101558009B1 (pt) |
CN (3) | CN103540632A (pt) |
AU (1) | AU2008312937B2 (pt) |
BR (1) | BRPI0818674B1 (pt) |
CA (1) | CA2701338C (pt) |
DK (1) | DK2202307T4 (pt) |
ES (1) | ES2499391T5 (pt) |
IL (2) | IL205051A (pt) |
MX (1) | MX2010004007A (pt) |
PL (1) | PL2202307T5 (pt) |
SG (1) | SG185302A1 (pt) |
SI (1) | SI2202307T2 (pt) |
TW (1) | TWI463010B (pt) |
WO (1) | WO2009051108A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0818674B1 (pt) * | 2007-10-15 | 2023-01-17 | Chugai Seiyaku Kabushiki Kaisha | Métodos para produção de um anticorpo inteiro ou de um fragmento do mesmo e para preparação de fármacos, bem como vetor recombinante |
KR102223417B1 (ko) | 2009-10-26 | 2021-03-05 | 에프. 호프만-라 로슈 아게 | 글리코실화된 면역글로불린의 제조 방법 |
CN107629124A (zh) * | 2010-12-28 | 2018-01-26 | 中外制药株式会社 | 动物细胞的培养方法 |
RU2015144020A (ru) * | 2013-03-15 | 2017-04-21 | Дженентек, Инк. | Среды для культивирования клеток и способы получения антител |
CA2913687C (en) | 2013-07-04 | 2022-12-13 | F. Hoffmann-La Roche Ag | Interference-suppressed immunoassay to detect anti-drug antibodies in serum samples |
US20190225694A1 (en) | 2016-06-28 | 2019-07-25 | Zaklady Farmaceutyczne Polpharma Sa | Recombinant production of monoclonal antibodies |
US20190374639A1 (en) | 2016-11-21 | 2019-12-12 | Polpharma Biologics S.A. | Aqueous pharmaceutical formulations |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
JPS6459878A (en) | 1987-08-31 | 1989-03-07 | Matsushita Electric Ind Co Ltd | Semiconductor laser protective circuit |
ES2139598T3 (es) | 1990-07-10 | 2000-02-16 | Medical Res Council | Procedimientos para la produccion de miembros de parejas de union especifica. |
GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
DE69133476T2 (de) | 1990-08-29 | 2006-01-05 | GenPharm International, Inc., Palo Alto | Transgene Mäuse fähig zur Produktion heterologer Antikörper |
CA2090969C (en) † | 1990-09-04 | 2001-08-21 | Russell Arthur Brierley | Production of insulin-like growth factor-1 in methylotrophic yeast cells |
DK0628639T3 (da) * | 1991-04-25 | 2000-01-24 | Chugai Pharmaceutical Co Ltd | Rekonstitueret humant antistof mod human interleukin-6-receptor |
ATE181571T1 (de) | 1991-09-23 | 1999-07-15 | Medical Res Council | Methoden zur herstellung humanisierter antikörper |
ES2227512T3 (es) | 1991-12-02 | 2005-04-01 | Medical Research Council | Produccion de anticuerpos contra auto-antigenos a partir de repertorios de segmentos de anticuerpos fijados en un fago. |
EP0746609A4 (en) | 1991-12-17 | 1997-12-17 | Genpharm Int | NON-HUMAN TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGOUS ANTIBODIES |
CA2131151A1 (en) | 1992-03-24 | 1994-09-30 | Kevin S. Johnson | Methods for producing members of specific binding pairs |
AU675661B2 (en) | 1992-07-24 | 1997-02-13 | Abgenix, Inc. | Generation of xenogeneic antibodies |
CA2161351C (en) | 1993-04-26 | 2010-12-21 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
GB9313509D0 (en) | 1993-06-30 | 1993-08-11 | Medical Res Council | Chemisynthetic libraries |
EP0731842A1 (en) | 1993-12-03 | 1996-09-18 | Medical Research Council | Recombinant binding proteins and peptides |
KR100261941B1 (ko) | 1994-07-13 | 2000-07-15 | 나가야마 오사무 | 사람의 인터루킨-8에 대한 재구성 사람항체 |
US5561053A (en) | 1994-08-05 | 1996-10-01 | Genentech, Inc. | Method for selecting high-expressing host cells |
CA2219361C (en) | 1995-04-27 | 2012-02-28 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
AU2466895A (en) | 1995-04-28 | 1996-11-18 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
EP0985033A4 (en) * | 1997-04-04 | 2005-07-13 | Biosite Inc | POLYVALENT AND POLYCLONAL LIBRARIES |
DE69830901T2 (de) | 1997-05-02 | 2006-05-24 | Genentech Inc., San Francisco | ein verfahren zur herstellung multispezifischer antikörper die heteromultimere und gemeinsame komponenten besitzen |
US20020062010A1 (en) | 1997-05-02 | 2002-05-23 | Genentech, Inc. | Method for making multispecific antibodies having heteromultimeric and common components |
US6171586B1 (en) * | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
EP1383800A4 (en) † | 2001-04-02 | 2004-09-22 | Idec Pharma Corp | RECOMBINANT ANTIBODIES CO-EXPRESSED WITH GNTIII |
US6605176B2 (en) | 2001-07-13 | 2003-08-12 | Taiwan Semiconductor Manufacturing Co., Ltd. | Aperture for linear control of vacuum chamber pressure |
US20030157641A1 (en) * | 2001-11-16 | 2003-08-21 | Idec Pharmaceuticals Corporation | Polycistronic expression of antibodies |
ATE420964T1 (de) * | 2001-11-16 | 2009-01-15 | Biogen Idec Inc | Polycistronische expression von antikörpern in cho zellen |
TW200510532A (en) | 2003-07-15 | 2005-03-16 | Chugai Pharmaceutical Co Ltd | IgM production by transformed cell and method of quantifying the same |
AU2005222963B2 (en) * | 2004-03-15 | 2009-10-29 | Biogen Idec Ma Inc. | Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing |
EP2314317A3 (en) * | 2004-07-09 | 2011-06-29 | Chugai Seiyaku Kabushiki Kaisha | Anti-glypican 3 antibody |
GB0425534D0 (en) * | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Process for obtaining antibodies |
CA2615983A1 (en) † | 2005-07-21 | 2007-02-01 | Abbott Laboratories | Multiple gene expression including sorf constructs and methods with polyproteins, pro-proteins, and proteolysis |
BRPI0818674B1 (pt) * | 2007-10-15 | 2023-01-17 | Chugai Seiyaku Kabushiki Kaisha | Métodos para produção de um anticorpo inteiro ou de um fragmento do mesmo e para preparação de fármacos, bem como vetor recombinante |
-
2008
- 2008-10-14 BR BRPI0818674-0A patent/BRPI0818674B1/pt active IP Right Grant
- 2008-10-14 SG SG2012076485A patent/SG185302A1/en unknown
- 2008-10-14 CA CA2701338A patent/CA2701338C/en active Active
- 2008-10-14 SI SI200831306T patent/SI2202307T2/sl unknown
- 2008-10-14 CN CN201310401442.2A patent/CN103540632A/zh active Pending
- 2008-10-14 US US12/734,094 patent/US9683027B2/en active Active
- 2008-10-14 AU AU2008312937A patent/AU2008312937B2/en active Active
- 2008-10-14 PL PL08838661T patent/PL2202307T5/pl unknown
- 2008-10-14 DK DK08838661.0T patent/DK2202307T4/da active
- 2008-10-14 CN CN200880106430A patent/CN101802192A/zh active Pending
- 2008-10-14 CN CN201610656433.1A patent/CN106244651A/zh active Pending
- 2008-10-14 MX MX2010004007A patent/MX2010004007A/es active IP Right Grant
- 2008-10-14 ES ES08838661T patent/ES2499391T5/es active Active
- 2008-10-14 EP EP08838661.0A patent/EP2202307B2/en active Active
- 2008-10-14 KR KR1020107008087A patent/KR101558009B1/ko active IP Right Grant
- 2008-10-14 JP JP2009538093A patent/JP4976502B2/ja active Active
- 2008-10-14 WO PCT/JP2008/068588 patent/WO2009051108A1/ja active Application Filing
- 2008-10-15 TW TW097139552A patent/TWI463010B/zh active
-
2010
- 2010-04-13 IL IL205051A patent/IL205051A/en active IP Right Grant
-
2012
- 2012-04-12 JP JP2012090908A patent/JP5788830B2/ja active Active
-
2015
- 2015-06-05 JP JP2015114464A patent/JP6092304B2/ja active Active
- 2015-07-23 IL IL240122A patent/IL240122B/en active IP Right Grant
-
2017
- 2017-02-08 JP JP2017020965A patent/JP6506786B2/ja active Active
- 2017-05-08 US US15/589,000 patent/US11136375B2/en active Active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/10/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |