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BRPI0818674A2 - Método para produção de anticorpos - Google Patents

Método para produção de anticorpos

Info

Publication number
BRPI0818674A2
BRPI0818674A2 BRPI0818674-0A2A BRPI0818674A BRPI0818674A2 BR PI0818674 A2 BRPI0818674 A2 BR PI0818674A2 BR PI0818674 A BRPI0818674 A BR PI0818674A BR PI0818674 A2 BRPI0818674 A2 BR PI0818674A2
Authority
BR
Brazil
Prior art keywords
antibody production
antibody
production
Prior art date
Application number
BRPI0818674-0A2A
Other languages
English (en)
Inventor
Yoshiki Yamada
Tatsuya Kiyasu
Kazuyuki Tabata
Akihiro Kuzumaki
Mai Yamashiro
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40567372&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0818674(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BRPI0818674A2 publication Critical patent/BRPI0818674A2/pt
Publication of BRPI0818674B1 publication Critical patent/BRPI0818674B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
BRPI0818674-0A 2007-10-15 2008-10-14 Métodos para produção de um anticorpo inteiro ou de um fragmento do mesmo e para preparação de fármacos, bem como vetor recombinante BRPI0818674B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2007-267384 2007-10-15
JP2007267384 2007-10-15
JP2008-103308 2008-04-11
JP2008103308 2008-04-11
PCT/JP2008/068588 WO2009051108A1 (ja) 2007-10-15 2008-10-14 抗体の製造方法

Publications (2)

Publication Number Publication Date
BRPI0818674A2 true BRPI0818674A2 (pt) 2014-10-14
BRPI0818674B1 BRPI0818674B1 (pt) 2023-01-17

Family

ID=40567372

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0818674-0A BRPI0818674B1 (pt) 2007-10-15 2008-10-14 Métodos para produção de um anticorpo inteiro ou de um fragmento do mesmo e para preparação de fármacos, bem como vetor recombinante

Country Status (17)

Country Link
US (2) US9683027B2 (pt)
EP (1) EP2202307B2 (pt)
JP (4) JP4976502B2 (pt)
KR (1) KR101558009B1 (pt)
CN (3) CN103540632A (pt)
AU (1) AU2008312937B2 (pt)
BR (1) BRPI0818674B1 (pt)
CA (1) CA2701338C (pt)
DK (1) DK2202307T4 (pt)
ES (1) ES2499391T5 (pt)
IL (2) IL205051A (pt)
MX (1) MX2010004007A (pt)
PL (1) PL2202307T5 (pt)
SG (1) SG185302A1 (pt)
SI (1) SI2202307T2 (pt)
TW (1) TWI463010B (pt)
WO (1) WO2009051108A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0818674B1 (pt) * 2007-10-15 2023-01-17 Chugai Seiyaku Kabushiki Kaisha Métodos para produção de um anticorpo inteiro ou de um fragmento do mesmo e para preparação de fármacos, bem como vetor recombinante
KR102223417B1 (ko) 2009-10-26 2021-03-05 에프. 호프만-라 로슈 아게 글리코실화된 면역글로불린의 제조 방법
CN107629124A (zh) * 2010-12-28 2018-01-26 中外制药株式会社 动物细胞的培养方法
RU2015144020A (ru) * 2013-03-15 2017-04-21 Дженентек, Инк. Среды для культивирования клеток и способы получения антител
CA2913687C (en) 2013-07-04 2022-12-13 F. Hoffmann-La Roche Ag Interference-suppressed immunoassay to detect anti-drug antibodies in serum samples
US20190225694A1 (en) 2016-06-28 2019-07-25 Zaklady Farmaceutyczne Polpharma Sa Recombinant production of monoclonal antibodies
US20190374639A1 (en) 2016-11-21 2019-12-12 Polpharma Biologics S.A. Aqueous pharmaceutical formulations

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
JPS6459878A (en) 1987-08-31 1989-03-07 Matsushita Electric Ind Co Ltd Semiconductor laser protective circuit
ES2139598T3 (es) 1990-07-10 2000-02-16 Medical Res Council Procedimientos para la produccion de miembros de parejas de union especifica.
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DE69133476T2 (de) 1990-08-29 2006-01-05 GenPharm International, Inc., Palo Alto Transgene Mäuse fähig zur Produktion heterologer Antikörper
CA2090969C (en) 1990-09-04 2001-08-21 Russell Arthur Brierley Production of insulin-like growth factor-1 in methylotrophic yeast cells
DK0628639T3 (da) * 1991-04-25 2000-01-24 Chugai Pharmaceutical Co Ltd Rekonstitueret humant antistof mod human interleukin-6-receptor
ATE181571T1 (de) 1991-09-23 1999-07-15 Medical Res Council Methoden zur herstellung humanisierter antikörper
ES2227512T3 (es) 1991-12-02 2005-04-01 Medical Research Council Produccion de anticuerpos contra auto-antigenos a partir de repertorios de segmentos de anticuerpos fijados en un fago.
EP0746609A4 (en) 1991-12-17 1997-12-17 Genpharm Int NON-HUMAN TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGOUS ANTIBODIES
CA2131151A1 (en) 1992-03-24 1994-09-30 Kevin S. Johnson Methods for producing members of specific binding pairs
AU675661B2 (en) 1992-07-24 1997-02-13 Abgenix, Inc. Generation of xenogeneic antibodies
CA2161351C (en) 1993-04-26 2010-12-21 Nils Lonberg Transgenic non-human animals capable of producing heterologous antibodies
GB9313509D0 (en) 1993-06-30 1993-08-11 Medical Res Council Chemisynthetic libraries
EP0731842A1 (en) 1993-12-03 1996-09-18 Medical Research Council Recombinant binding proteins and peptides
KR100261941B1 (ko) 1994-07-13 2000-07-15 나가야마 오사무 사람의 인터루킨-8에 대한 재구성 사람항체
US5561053A (en) 1994-08-05 1996-10-01 Genentech, Inc. Method for selecting high-expressing host cells
CA2219361C (en) 1995-04-27 2012-02-28 Abgenix, Inc. Human antibodies derived from immunized xenomice
AU2466895A (en) 1995-04-28 1996-11-18 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP0985033A4 (en) * 1997-04-04 2005-07-13 Biosite Inc POLYVALENT AND POLYCLONAL LIBRARIES
DE69830901T2 (de) 1997-05-02 2006-05-24 Genentech Inc., San Francisco ein verfahren zur herstellung multispezifischer antikörper die heteromultimere und gemeinsame komponenten besitzen
US20020062010A1 (en) 1997-05-02 2002-05-23 Genentech, Inc. Method for making multispecific antibodies having heteromultimeric and common components
US6171586B1 (en) * 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
EP1383800A4 (en) 2001-04-02 2004-09-22 Idec Pharma Corp RECOMBINANT ANTIBODIES CO-EXPRESSED WITH GNTIII
US6605176B2 (en) 2001-07-13 2003-08-12 Taiwan Semiconductor Manufacturing Co., Ltd. Aperture for linear control of vacuum chamber pressure
US20030157641A1 (en) * 2001-11-16 2003-08-21 Idec Pharmaceuticals Corporation Polycistronic expression of antibodies
ATE420964T1 (de) * 2001-11-16 2009-01-15 Biogen Idec Inc Polycistronische expression von antikörpern in cho zellen
TW200510532A (en) 2003-07-15 2005-03-16 Chugai Pharmaceutical Co Ltd IgM production by transformed cell and method of quantifying the same
AU2005222963B2 (en) * 2004-03-15 2009-10-29 Biogen Idec Ma Inc. Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing
EP2314317A3 (en) * 2004-07-09 2011-06-29 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody
GB0425534D0 (en) * 2004-11-19 2004-12-22 Celltech R&D Ltd Process for obtaining antibodies
CA2615983A1 (en) 2005-07-21 2007-02-01 Abbott Laboratories Multiple gene expression including sorf constructs and methods with polyproteins, pro-proteins, and proteolysis
BRPI0818674B1 (pt) * 2007-10-15 2023-01-17 Chugai Seiyaku Kabushiki Kaisha Métodos para produção de um anticorpo inteiro ou de um fragmento do mesmo e para preparação de fármacos, bem como vetor recombinante

Also Published As

Publication number Publication date
JP4976502B2 (ja) 2012-07-18
JP5788830B2 (ja) 2015-10-07
ES2499391T5 (es) 2021-12-22
CA2701338A1 (en) 2009-04-23
US9683027B2 (en) 2017-06-20
JP6092304B2 (ja) 2017-03-08
IL205051A0 (en) 2010-11-30
JP2012143246A (ja) 2012-08-02
CN106244651A (zh) 2016-12-21
TWI463010B (zh) 2014-12-01
PL2202307T5 (pl) 2021-10-04
SI2202307T1 (sl) 2014-11-28
MX2010004007A (es) 2010-06-15
US11136375B2 (en) 2021-10-05
BRPI0818674B1 (pt) 2023-01-17
IL240122A0 (en) 2015-09-24
EP2202307A4 (en) 2012-01-25
DK2202307T4 (da) 2021-10-04
CN103540632A (zh) 2014-01-29
AU2008312937A1 (en) 2009-04-23
AU2008312937B2 (en) 2015-01-22
DK2202307T3 (da) 2014-09-15
JP2015198663A (ja) 2015-11-12
ES2499391T3 (es) 2014-09-29
SG185302A1 (en) 2012-11-29
TW200934867A (en) 2009-08-16
SI2202307T2 (sl) 2021-11-30
JP6506786B2 (ja) 2019-04-24
PL2202307T3 (pl) 2015-02-27
KR20100074184A (ko) 2010-07-01
WO2009051108A1 (ja) 2009-04-23
EP2202307B1 (en) 2014-08-20
IL240122B (en) 2019-02-28
JPWO2009051108A1 (ja) 2011-03-03
CA2701338C (en) 2018-09-18
JP2017079794A (ja) 2017-05-18
CN101802192A (zh) 2010-08-11
IL205051A (en) 2015-09-24
US20100291627A1 (en) 2010-11-18
US20170275351A1 (en) 2017-09-28
EP2202307A1 (en) 2010-06-30
US20210300996A1 (en) 2021-09-30
EP2202307B2 (en) 2021-07-14
KR101558009B1 (ko) 2015-10-19

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/10/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.