Nothing Special   »   [go: up one dir, main page]

BE2020C517I2 - - Google Patents

Download PDF

Info

Publication number
BE2020C517I2
BE2020C517I2 BE2020C517C BE2020C517C BE2020C517I2 BE 2020C517 I2 BE2020C517 I2 BE 2020C517I2 BE 2020C517 C BE2020C517 C BE 2020C517C BE 2020C517 C BE2020C517 C BE 2020C517C BE 2020C517 I2 BE2020C517 I2 BE 2020C517I2
Authority
BE
Belgium
Application number
BE2020C517C
Other languages
Dutch (nl)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32607514&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE2020C517(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BE2020C517I2 publication Critical patent/BE2020C517I2/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Compositions Of Oxide Ceramics (AREA)
BE2020C517C 2004-05-18 2020-06-11 BE2020C517I2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0411056.5A GB0411056D0 (en) 2004-05-18 2004-05-18 Organic compounds

Publications (1)

Publication Number Publication Date
BE2020C517I2 true BE2020C517I2 (de) 2024-08-08

Family

ID=32607514

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2020C517C BE2020C517I2 (de) 2004-05-18 2020-06-11

Country Status (34)

Country Link
US (6) US20080267886A1 (de)
EP (3) EP1755590B1 (de)
JP (2) JP5567252B2 (de)
KR (2) KR101360556B1 (de)
CN (1) CN1953745A (de)
AT (1) ATE521348T1 (de)
AU (1) AU2005244439C1 (de)
BE (1) BE2020C517I2 (de)
BR (1) BRPI0511327B8 (de)
CA (1) CA2563302C (de)
CY (4) CY1112086T1 (de)
DK (2) DK1755590T3 (de)
EC (1) ECSP066950A (de)
ES (2) ES2775979T3 (de)
FR (1) FR20C1018I2 (de)
GB (1) GB0411056D0 (de)
HK (1) HK1105579A1 (de)
HU (3) HUE048936T2 (de)
IL (1) IL179013A (de)
LT (3) LT2228064T (de)
LU (1) LUC00155I2 (de)
MA (1) MA28598B1 (de)
MX (1) MXPA06013382A (de)
NO (2) NO334760B1 (de)
NZ (1) NZ550369A (de)
PL (2) PL1755590T3 (de)
PT (2) PT1755590E (de)
RU (1) RU2388465C2 (de)
SE (1) SE1755590T5 (de)
SG (1) SG153836A1 (de)
SI (2) SI1755590T1 (de)
TN (1) TNSN06377A1 (de)
WO (1) WO2005110402A1 (de)
ZA (1) ZA200608123B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
EP1863476B1 (de) * 2005-03-16 2016-02-03 MEDA Pharma GmbH & Co. KG Kombination aus anticholinergika und leukotrien-rezeptorantagonisten zur behandlung von atemwegserkrankungen
EP1879571A1 (de) * 2005-04-23 2008-01-23 Boehringer Ingelheim International GmbH Arzneimittelkombination für die inhalation enthaltend neben einem anticholinergikum ein betamimetikum und ein steroid
GB0511065D0 (en) * 2005-05-31 2005-07-06 Novartis Ag Organic compounds
GB0523656D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
GB0523655D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
EP2044025B1 (de) 2006-06-30 2012-10-03 Novartis AG Chinolinonderivate und pharmazeutische zusammensetzungen daraus
EP1878722A1 (de) * 2006-07-13 2008-01-16 Novartis AG Chinolinonderivate und ihre pharmazeutischen Zusammensetzungen
EP1938822A1 (de) * 2006-12-21 2008-07-02 Novartis AG Kombinationtherapie zur Behandlung von Ventilationsstörungen
US8815258B2 (en) * 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
PL3111926T3 (pl) * 2009-05-29 2020-06-29 Pearl Therapeutics, Inc. Kompozycje, sposoby i układy do dostarczania dwóch lub większej liczby środków czynnych do układu oddechowego
EP2440196A4 (de) * 2009-06-09 2013-01-02 Elevation Pharmaceuticals Inc Behandlung der chronisch obstruktiven lungenkrankheit mit einem zerstäubten beta-2-agonisten oder durch kombination eines zerstäubten beta-2-agonisten mit der verabreichung von anticholinergika
EP2515853B1 (de) 2009-12-23 2014-03-19 Chiesi Farmaceutici S.p.A. Kombinationstherapie für COPD
ES2468840T7 (es) 2009-12-23 2023-11-29 Chiesi Farm Spa Terapia combinada para EPOC
KR20140012989A (ko) 2011-02-17 2014-02-04 시플라 리미티드 글리코피롤레이트 및 베타2-효능제의 조합
KR101317924B1 (ko) * 2011-05-17 2013-10-16 김동진 글리코피롤레이트의 합성방법 및 이 활성성분을 함유하는 약학적 조성물의 제조방법
WO2014007767A1 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Dry powder inhalers comprising a carrier other than lactose and a ternary component
EA201590019A1 (ru) 2012-07-05 2015-09-30 Арвен Айлак Санайи Ве Тиджарет А.С. Ингаляторы сухого порошка, содержащие носитель, отличный от лактозы
KR101460694B1 (ko) * 2012-09-07 2014-11-11 성광제약주식회사 글리코피롤레이트의 신규 합성방법 및 이 활성성분을 함유하는 약학적 조성물
CN103784401A (zh) * 2012-10-29 2014-05-14 北京市丰硕维康技术开发有限责任公司 一种治疗呼吸道疾病的溶液型定量吸入气雾剂及制备方法
EP3473615B1 (de) 2013-02-28 2022-01-19 Journey Medical Corporation Glycopyrrolat-salze
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
CA2905542C (en) 2013-03-15 2022-05-03 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials
HUE039513T2 (hu) 2013-12-30 2019-01-28 Chiesi Farm Spa Glikopirrónium-bromid és formoterol kombinációját tartalmazó nyomás alatti stabil aeroszol oldatkészítmény
PL3191081T3 (pl) 2014-09-09 2020-09-07 Vectura Limited Formulacja zawierająca glikopirolan, sposób i urządzenie
CN109069390A (zh) * 2016-04-11 2018-12-21 苏文生命科学有限公司 格隆溴铵的外用喷雾制剂
US10098837B2 (en) 2016-07-28 2018-10-16 Chiesi Farmaceutici S.P.A. Combination therapy for COPD
WO2020217143A1 (en) * 2019-04-23 2020-10-29 Glenmark Pharmaceutical Limited Inhalable dry powder composition comprising gly copyrronium, indacaterol and fluticasone
CN112804997B (zh) * 2019-06-03 2022-02-22 广州谷森制药有限公司 含马来酸茚达特罗和格隆溴铵溶液的可吸入制剂
EP4069189A1 (de) 2019-12-02 2022-10-12 Chiesi Farmaceutici S.p.A. Edelstahldose für druckdosierinhalatoren

Family Cites Families (188)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2956062A (en) * 1959-02-26 1960-10-11 Robins Co Inc A H Esters of amino alcohols
US6204261B1 (en) 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
GB1219606A (en) 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
IT1016489B (it) 1974-03-18 1977-05-30 Isf Spa Inalatore
JPS6235216A (ja) 1985-08-09 1987-02-16 Noritoshi Nakabachi 不均質物質層の層厚非破壊測定方法および装置
GB8916480D0 (en) 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8923590D0 (en) 1989-10-19 1989-12-06 Pfizer Ltd Antimuscarinic bronchodilators
US5416013A (en) 1990-04-04 1995-05-16 Sterling Winthrop Inc. Interleukin 1β protease and interleukin 1β protease inhibitors
PT100441A (pt) 1991-05-02 1993-09-30 Smithkline Beecham Corp Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
US5451700A (en) 1991-06-11 1995-09-19 Ciba-Geigy Corporation Amidino compounds, their manufacture and methods of treatment
DE69226820T2 (de) 1991-06-21 1999-05-12 Merck & Co., Inc., Rahway, N.J. Peptidylderivate als Inhibitoren von Interleukin-1B-konvertierenden Enzymen
DE69133354T2 (de) 1991-08-30 2004-11-11 Vertex Pharmaceuticals Inc., Cambridge Interleukin 1-beta protease und ihre inhibitoren
EP0547699A1 (de) 1991-12-19 1993-06-23 Merck & Co. Inc. Peptidylderivate als Inhibitoren von Interleukin-1-Beta-konvertierenden Enzymen
WO1993014777A1 (en) 1992-01-31 1993-08-05 Merck & Co., Inc. PEPTIDYL DERIVATIVES AS INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME
AU3666893A (en) 1992-02-21 1993-09-13 Merck & Co., Inc. Peptidyl derivatives as inhibitors of interleukin-1beta converting enzyme
WO1993018007A1 (en) 1992-03-13 1993-09-16 Tokyo Tanabe Company Limited Novel carbostyril derivative
JP3192424B2 (ja) 1992-04-02 2001-07-30 スミスクライン・ビーチャム・コーポレイション アレルギーまたは炎症疾患の治療用化合物
AU3924993A (en) 1992-04-02 1993-11-08 Smithkline Beecham Corporation Compounds useful for treating inflammatory diseases and inhibiting production of tumor necrosis factor
WO1993019749A1 (en) 1992-04-02 1993-10-14 Smithkline Beecham Corporation Compounds useful for treating allergic and inflammatory diseases
JPH08500242A (ja) 1992-06-24 1996-01-16 メルク エンド カンパニー インコーポレーテッド インターロイキン１β前駆体の転換酵素をコードするＤＮＡ
ES2117133T3 (es) 1992-07-31 1998-08-01 Pfizer Derivados peptidilicos del acido 4-amino-2,2-difluoro-3-oxo-1,6-hexanodioico como agentes antiinflamatorios.
US5395958A (en) 1992-09-30 1995-03-07 Mitsubishi Kasei Corporation Cyclopropene derivatives
CA2109646C (en) 1992-11-24 2000-03-07 Gaston O. Daumy Para-nitroanilide peptides
GB9301000D0 (en) 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
US5656600A (en) 1993-03-25 1997-08-12 Corvas International, Inc. α-ketoamide derivatives as inhibitors of thrombosis
US5411985A (en) 1993-05-17 1995-05-02 Merck & Co., Inc. Gamma-pyrone-3-acetic acid as an inhibitor or interleukin-1 β inventory enzyme
JPH0789951A (ja) 1993-06-03 1995-04-04 Sterling Winthrop Inc インターロイキン−１β転換酵素阻害剤
JPH0725887A (ja) 1993-06-04 1995-01-27 Sterling Winthrop Inc インターロイキン−１β転換酵素阻害剤
DE69408598T2 (de) 1993-06-08 1998-09-17 Vertex Pharmaceuticals Inc Cam Pyridazine als Interleukin-1-beta Verwandlungsenzym Inhibitoren
DE4326959C2 (de) 1993-08-12 1995-07-06 Henkel Kgaa Verwendung von Fettsäure-N-alkylpolyhydroxyalkylamiden
US6596260B1 (en) 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
US5756466A (en) 1994-06-17 1998-05-26 Vertex Pharmaceuticals, Inc. Inhibitors of interleukin-1β converting enzyme
US5716929A (en) 1994-06-17 1998-02-10 Vertex Pharmaceuticals, Inc. Inhibitors of interleukin-1β converting enzyme
GB9414193D0 (en) 1994-07-14 1994-08-31 Glaxo Group Ltd Compounds
GB9414208D0 (en) 1994-07-14 1994-08-31 Glaxo Group Ltd Compounds
US5565430A (en) 1994-08-02 1996-10-15 Sterling Winthrop Inc. Azaaspartic acid analogs as interleukin-1β converting enzyme inhibitors
ATE261324T1 (de) 1995-12-07 2004-03-15 Jago Res Ag Mundstück für einen inhalator zur mehrfachen dosisweisen abgabe eines pharmakologischen trockenpulvers
US5843904A (en) 1995-12-20 1998-12-01 Vertex Pharmaceuticals, Inc. Inhibitors of interleukin-1βconverting enzyme
US6610683B2 (en) 1996-09-12 2003-08-26 Idun Pharmaceuticals, Inc. Treatment of infectious disease using interleukin-1β-converting enzyme (ICE)/CED-3 family inhibitors
WO1998011129A1 (en) 1996-09-12 1998-03-19 Idun Pharmaceuticals, Incorporated C-TERMINAL MODIFIED (N-SUBSTITUTED)-2-INDOLYL DIPEPTIDES AS INHIBITORS OF THE ICE/ced-3 FAMILY OF CYSTEINE PROTEASES
DE69711845T2 (de) 1996-09-12 2002-10-31 Idun Pharmaceuticals, Inc. Neue tricyclische verbindungen mit ice/ced-3 protease familie-hemmenden eigenschaften
CA2265853C (en) 1996-09-12 2010-08-03 Idun Pharmaceuticals, Inc. Inhibition of apoptosis using interleukin-1.beta.-converting enzyme (ice)/ced-3 family inhibitors
GB9622386D0 (en) 1996-10-28 1997-01-08 Sandoz Ltd Organic compounds
US6613795B2 (en) 1996-11-11 2003-09-02 Christian Noe Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments
JP2001504459A (ja) 1996-11-11 2001-04-03 ノエ・クリスティアン・エル 対掌体純粋な、塩基性アリール―シクロアルキル―ヒドロキシカルボン酸エステル、その製造方法及びこれを薬剤に使用する方法
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
US6054487A (en) 1997-03-18 2000-04-25 Basf Aktiengesellschaft Methods and compositions for modulating responsiveness to corticosteroids
TR199902615T2 (xx) 1997-03-18 2000-03-21 Basf Aktiengesellschaft Kortikosteroidlere verilen cevab�n mod�lasyonuna y�nelik metodlar ve kompozisyonlar.
AR016384A1 (es) 1997-07-30 2001-07-04 Smithkline Beecham Corp Inhibidores de caspasas, composiciones farmaceuticas que comprenden dichos inhibidores de caspasas y uso de los inhibidores de caspasas para prepararun medicamento util para el tratamiento de apoptosis y desordenes asociados con excesiva actividad de la convertosa il-1 beta.
AU9281298A (en) 1997-10-01 1999-04-23 Kyowa Hakko Kogyo Co. Ltd. Benzodioxole derivatives
GB9723566D0 (en) 1997-11-08 1998-01-07 Glaxo Group Ltd Chemical compounds
GB9723590D0 (en) 1997-11-08 1998-01-07 Glaxo Group Ltd Chemical compounds
GB9723589D0 (en) 1997-11-08 1998-01-07 Glaxo Group Ltd Chemical compounds
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
AR017457A1 (es) 1998-02-14 2001-09-05 Glaxo Group Ltd Compuestos derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol, procesos para su preparacion, composiciones que los contienen y su uso en terapia para el tratamiento de enfermedades inflamatorias.
BR9909660A (pt) 1998-03-19 2000-11-21 Vertex Pharma Inibidores de caspases
US6362371B1 (en) 1998-06-08 2002-03-26 Advanced Medicine, Inc. β2- adrenergic receptor agonists
AR019322A1 (es) 1998-06-18 2002-02-13 Smithkline Beecham Corp Derivados de sulfonilo sustituido por heterociclo-etanodionanilina sustituida por heterociclo, composicion farmaceutica que los contiene y su uso para lamanufactura de un medicamento
GB9813540D0 (en) 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds
GB9813535D0 (en) 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds
GB9813565D0 (en) 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds
PL345062A1 (en) 1998-06-23 2001-11-19 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
BR9815931A (pt) 1998-06-30 2001-02-20 Dow Chemical Co Polióis poliméricos, um processo para sua produção, e espuma de poliuretanoobtida
DE59911149D1 (de) 1998-07-24 2004-12-30 Jago Res Ag Muttenz Medizinische aerosolformulierungen
ES2264826T3 (es) 1998-10-16 2007-01-16 Pfizer Inc. Derivados de adenina.
ATE233550T1 (de) 1998-11-13 2003-03-15 Jago Res Ag Trockenpulver zur inhalation
GB9902689D0 (en) 1999-02-08 1999-03-31 Novartis Ag Organic compounds
DE19921693A1 (de) 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
GB9913083D0 (en) * 1999-06-04 1999-08-04 Novartis Ag Organic compounds
YU25500A (sh) 1999-05-11 2003-08-29 Pfizer Products Inc. Postupak za sintezu analoga nukleozida
US20040002548A1 (en) * 1999-05-12 2004-01-01 Boehringer Ingelheim Pharma Kg Medicament compositions containing anticholinergically-effective compounds and betamimetics
US6683115B2 (en) 1999-06-02 2004-01-27 Theravance, Inc. β2-adrenergic receptor agonists
GB9913932D0 (en) 1999-06-15 1999-08-18 Pfizer Ltd Purine derivatives
US6322771B1 (en) 1999-06-18 2001-11-27 University Of Virginia Patent Foundation Induction of pharmacological stress with adenosine receptor agonists
EA006685B1 (ru) 1999-08-21 2006-02-24 Алтана Фарма Аг Синергетическая композиция
AU7127600A (en) 1999-09-17 2001-04-17 Basf Aktiengesellschaft Methods and compositions for modulating responsiveness to corticosteroids
CO5180581A1 (es) 1999-09-30 2002-07-30 Pfizer Prod Inc Compuestos para el tratamiento de la isquemia ciones farmaceuticas que los contienen para el tratamiento de la isquemia
GB9924363D0 (en) 1999-10-14 1999-12-15 Pfizer Central Res Purine derivatives
GB9924361D0 (en) 1999-10-14 1999-12-15 Pfizer Ltd Purine derivatives
OA11558A (en) 1999-12-08 2004-06-03 Advanced Medicine Inc Beta 2-adrenergic receptor agonists.
GB0003960D0 (en) 2000-02-18 2000-04-12 Pfizer Ltd Purine derivatives
US6369115B1 (en) 2000-03-20 2002-04-09 Dura Pharmaceuticals, Inc. Stabilized powder formulations
GB0008660D0 (en) 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
CZ20023537A3 (cs) 2000-04-27 2003-02-12 Boehringer Ingelheim Pharma Kg Betamimetika, způsob jejich výroby a použití jako farmaceutický prostředek
TWI227240B (en) 2000-06-06 2005-02-01 Pfizer 2-aminocarbonyl-9H-purine derivatives
DE20122417U1 (de) 2000-06-27 2005-08-04 Laboratorios S.A.L.V.A.T., S.A., Esplugues De Llobregat Von Arylalkylaminen abgeleitete Carbamate
GB0015727D0 (en) 2000-06-27 2000-08-16 Pfizer Ltd Purine derivatives
GB0015876D0 (en) 2000-06-28 2000-08-23 Novartis Ag Organic compounds
DE10038639A1 (de) 2000-07-28 2002-02-21 Schering Ag Nichtsteroidale Entzündungshemmer
AU7649701A (en) 2000-08-05 2002-02-18 Glaxo Group Ltd 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents
GB0022695D0 (en) 2000-09-15 2000-11-01 Pfizer Ltd Purine Derivatives
US20020193392A1 (en) 2000-11-13 2002-12-19 Christel Schmelzer Pharmaceutical compositions based on tiotropium salts of salts of salmeterol
GB0028383D0 (en) 2000-11-21 2001-01-03 Novartis Ag Organic compounds
GB0029562D0 (en) 2000-12-04 2001-01-17 Novartis Ag Organic compounds
WO2002051841A1 (en) 2000-12-22 2002-07-04 Almirall Prodesfarma Ag Quinuclidine carbamate derivatives and their use as m3 antagonists
KR100869721B1 (ko) 2000-12-28 2008-11-21 알미랄 에이쥐 신규한 퀴누클리딘 유도체 및 그를 함유한 의약 조성물
US20020179087A1 (en) 2001-02-01 2002-12-05 Karl-Heinz Bozung Pharmaceutical compositions containing an oxitropium salt and a betamimetic
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
ATE365720T1 (de) 2001-03-08 2007-07-15 Glaxo Group Ltd Agonisten von beta-adrenorezeptoren
EP1241176A1 (de) 2001-03-16 2002-09-18 Pfizer Products Inc. Purinderivate zur Behandlung von Ischämie
ES2296923T3 (es) 2001-03-22 2008-05-01 Glaxo Group Limited Derivados formanilidas como agonistas del adrenorreceptor beta2.
WO2002085899A1 (en) 2001-04-19 2002-10-31 Vertex Pharmaceuticals Incorporated Heterocyclyldicarbamides as caspase inhibitors
DE60229372D1 (de) 2001-04-30 2008-11-27 Glaxo Group Ltd Antiphlogistische 7.beta.-carbothioate esterderivate von androstan mit einer 17.alpha.-zyklischen estergruppe
PL366899A1 (en) 2001-05-25 2005-02-07 Pfizer Inc. An adenosine a2a receptor agonist and an anticholinergic agent in combination for treating obstructive airways diseases
DE60227254D1 (de) 2001-06-12 2008-08-07 Glaxo Group Ltd Neue anti inflammatorische 17.alpha.-heterozyklische ester von 17.beta.-carbothioat androstan derivativen
DK2327767T3 (en) 2001-06-21 2015-07-27 Basf Enzymes Llc nitrilases
ITMI20010357U1 (it) 2001-06-28 2002-12-30 Plastiape Spa Dispositivo inalatore
PL211953B1 (pl) 2001-09-14 2012-07-31 Glaxo Group Ltd Pochodna fenetanoloaminy, zawierający ją środek farmaceutyczny i zastosowanie pochodnej fenetanoloaminy
IL160896A0 (en) 2001-10-17 2004-08-31 Ucb Sa Quinuclidine derivatives, processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors
GB0125259D0 (en) 2001-10-20 2001-12-12 Glaxo Group Ltd Novel compounds
AR037517A1 (es) 2001-11-05 2004-11-17 Novartis Ag Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria
MXPA04004388A (es) 2001-11-09 2005-05-16 Cv Therapeutics Inc Antagonistas del receptor a2b de adenosina.
US6653323B2 (en) 2001-11-13 2003-11-25 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
TWI249515B (en) 2001-11-13 2006-02-21 Theravance Inc Aryl aniline beta2 adrenergic receptor agonists
WO2003048181A1 (en) 2001-12-01 2003-06-12 Glaxo Group Limited 17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
BR0215348A (pt) 2001-12-20 2004-11-16 S A L V A T Lab Sa Derivados de carbamato de 1-alquil-1-azoniabiciclo[2-2]octano e uso destes como antagonistas do receptor muscarìnico
WO2003072592A1 (en) 2002-01-15 2003-09-04 Glaxo Group Limited 17.alpha-cycloalkyl/cycloylkenyl esters of alkyl-or haloalkyl-androst-4-en-3-on-11.beta.,17.alpha.-diol 17.beta.-carboxylates as anti-inflammatory agents
WO2003062259A2 (en) 2002-01-21 2003-07-31 Glaxo Group Limited Non-aromatic 17.alpha.-esters of androstane-17.beta.-carboxylate esters as anti-inflammatory agents
GB0202216D0 (en) 2002-01-31 2002-03-20 Glaxo Group Ltd Novel compounds
GB0204719D0 (en) 2002-02-28 2002-04-17 Glaxo Group Ltd Medicinal compounds
US6933410B2 (en) 2002-03-08 2005-08-23 Novartis Ag Process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine
ES2298508T3 (es) 2002-03-26 2008-05-16 Boehringer Ingelheim Pharmaceuticals Inc. Mimeticos de glucocorticoides, metodos para prepararlos, composiciones farmaceuticas y sus usos.
WO2003082787A1 (en) 2002-03-26 2003-10-09 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
WO2003086408A1 (en) 2002-04-10 2003-10-23 University Of Virginia Patent Foundation Use of a2a adenosine receptor agonists for the treatment of inflammatory diseases
EP1496892B1 (de) 2002-04-11 2011-01-26 Merck Sharp & Dohme Corp. 1h-benzo(f)indazol-5-yl-derivate als selektive glucocorticoid-rezeptor-modulatoren
ES2206021B1 (es) 2002-04-16 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de pirrolidinio.
AU2003222841A1 (en) 2002-04-25 2003-11-10 Glaxo Group Limited Phenethanolamine derivatives
JP2005527618A (ja) 2002-05-28 2005-09-15 セラヴァンス インコーポレーテッド アルコキシアリールβ２アドレナリン作動性レセプターアゴニスト
ES2201907B1 (es) 2002-05-29 2005-06-01 Almirall Prodesfarma, S.A. Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
US7186864B2 (en) 2002-05-29 2007-03-06 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
DE10224888A1 (de) 2002-06-05 2003-12-24 Merck Patent Gmbh Pyridazinderivate
US7074806B2 (en) 2002-06-06 2006-07-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
DE10225574A1 (de) 2002-06-10 2003-12-18 Merck Patent Gmbh Aryloxime
DE10227269A1 (de) 2002-06-19 2004-01-08 Merck Patent Gmbh Thiazolderivate
CA2490043A1 (en) 2002-06-25 2003-12-31 Merck Frosst Canada & Co. 8-(biaryl) quinoline pde4 inhibitors
ES2204295B1 (es) 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
AU2003281219A1 (en) 2002-07-02 2004-01-23 Bernard Cote Di-aryl-substituted-ethane pyridone pde4 inhibitors
WO2004005229A1 (en) 2002-07-08 2004-01-15 Pfizer Products Inc. Modulators of the glucocorticoid receptor
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
TW200409746A (en) 2002-07-26 2004-06-16 Theravance Inc Crystalline β2 adrenergic receptor agonist
PE20050130A1 (es) * 2002-08-09 2005-03-29 Novartis Ag Compuestos organicos
JP4555684B2 (ja) 2002-08-10 2010-10-06 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｐｄｅ４阻害剤としての、ピロリジンジオンにより置換されたピペリジン−フタラゾン
WO2004018449A1 (en) 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
US20060166995A1 (en) 2002-08-10 2006-07-27 Altana Pharma Ag Piperidine-n-oxide-derivatives
CA2494650A1 (en) 2002-08-10 2004-03-04 Altana Pharma Ag Pyridazinone-derivatives as pde4 inhibitors
CA2495597A1 (en) 2002-08-17 2004-03-04 Altana Pharma Ag Novel phenanthridines
RS20050117A (en) 2002-08-17 2007-06-04 Altana Pharma Ag., Novel benzonaphthyridines
ATE403648T1 (de) 2002-08-21 2008-08-15 Boehringer Ingelheim Pharma Substituierte dihydrochinoline als glucocorticoid-mmimetika,verfahren zu deren herstellung, pharmazeutische zubereitungen und deren verwendung
GB0219512D0 (en) 2002-08-21 2002-10-02 Norton Healthcare Ltd Inhalation compositions with high drug ratios
US7288562B2 (en) 2002-08-23 2007-10-30 Ranbaxy Laboratories Limited Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives as muscarinic receptor antagonists
AU2003255493B8 (en) 2002-08-29 2009-03-26 Takeda Gmbh 2-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors
DE60311662T2 (de) 2002-08-29 2007-10-25 Altana Pharma Ag 3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren
ES2349164T3 (es) 2002-08-29 2010-12-28 Boehringer Ingelheim Pharmaceuticals Inc. Derivados de 3-(sulfonamidoetil)-indol para uso como compuestos miméticos de glucocorticoides en el tratamiento de enfermedades inflamatorias, alérgicas y proliferativas.
GB0220730D0 (en) 2002-09-06 2002-10-16 Glaxo Group Ltd Medicinal compounds
JP2006096662A (ja) 2002-09-18 2006-04-13 Sumitomo Pharmaceut Co Ltd 新規６−置換ウラシル誘導体及びアレルギー性疾患の治療剤
WO2004026248A2 (en) 2002-09-20 2004-04-01 Merck & Co., Inc. Octahydro-2-h-naphtho[1,2-f] indole-4-carboxamide derivatives as selective glucocorticoid receptor modulators
JP2004107299A (ja) 2002-09-20 2004-04-08 Japan Energy Corp 新規１−置換ウラシル誘導体及びアレルギー性疾患の治療剤
DE10246374A1 (de) 2002-10-04 2004-04-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika mit verlängerter Wirkungsdauer, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
JP4490911B2 (ja) 2002-10-11 2010-06-30 ファイザー・インク β−２アゴニストとしてのインドール誘導体
DE60315492T2 (de) 2002-10-22 2008-04-24 Glaxo Group Ltd., Greenford Medizinisch verwendbare arylethanolamin verbindungen
KR20050065624A (ko) 2002-10-23 2005-06-29 그렌마크 파머수티칼스 엘티디. 염증성 및 알레르기 질환의 치료에 유용한 신규한트리사이클릭 화합물, 이의 제조 방법 및 이를 함유하는약제 조성물
EP1556342B1 (de) 2002-10-28 2008-03-26 Glaxo Group Limited Phenethanolamin-derivate zur behandlung von atemwegserkrankungen
GB0225287D0 (en) 2002-10-30 2002-12-11 Glaxo Group Ltd Novel compounds
GB0225535D0 (en) 2002-11-01 2002-12-11 Glaxo Group Ltd Medicinal compounds
GB0225540D0 (en) 2002-11-01 2002-12-11 Glaxo Group Ltd Medicinal compounds
DE10253220A1 (de) 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Dihydroxy-Methyl-Phenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE10253282A1 (de) 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
DE10253426B4 (de) 2002-11-15 2005-09-22 Elbion Ag Neue Hydroxyindole, deren Verwendung als Inhibitoren der Phosphodiesterase 4 und Verfahren zu deren Herstellung
DE10261874A1 (de) 2002-12-20 2004-07-08 Schering Ag Nichtsteroidale Entzündungshemmer
ES2291729T7 (es) 2003-01-09 2010-03-31 Astellas Pharma Inc. Derivados de pirrolopiridazina.
CA2512987C (en) 2003-01-21 2011-06-14 Merck & Co., Inc. 17-carbamoyloxy cortisol derivatives as selective glucocorticoid receptor modulators
TWI324150B (en) 2003-02-28 2010-05-01 Novartis Ag Process for preparing 5-[(r)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-(1h)-quinolin-2-one salt
EP1460064A1 (de) 2003-03-14 2004-09-22 Pfizer Limited Indole-2-carboxamide als beta-2 Agonisten
PE20100399A1 (es) 2003-04-02 2010-06-01 Novartis Ag Procedimiento para preparar oxi-(1h)-quinolin-2-onas 5-(alfa-haloacetil)-8-sustituidas
US7745462B2 (en) 2003-04-04 2010-06-29 Novartis Ag Quinoline-2-one derivatives for the treatment of airways diseases
TWI328009B (en) 2003-05-21 2010-08-01 Glaxo Group Ltd Quinoline derivatives as phosphodiesterase inhibitors
GB0312832D0 (en) 2003-06-04 2003-07-09 Pfizer Ltd 2-amino-pyridine derivatives useful for the treatment of diseases
JP2006526604A (ja) 2003-06-04 2006-11-24 ファイザー・インク β−２アドレナリン受容体アゴニストとしての２−アミノ−ピリジン誘導体
EP1636222A1 (de) 2003-06-11 2006-03-22 Merck Frosst Canada Ltd. 7-[(1,3-thiazol-2-yl)thio]-coumarinderivative und deren verwendung als inhibitoren der leukotrienbiosynthese
TW200510298A (en) 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
WO2004111044A1 (en) 2003-06-17 2004-12-23 Glenmark Pharmaceuticals Ltd. Tricyclic compounds useful for the treatment of inflammatory and allergic disorders:process for their preparation
SE527189C2 (sv) * 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser för formaterol och ett antikolinergiskt medel
GB0316290D0 (en) 2003-07-11 2003-08-13 Glaxo Group Ltd Novel compounds
JP2007524698A (ja) * 2004-02-27 2007-08-30 アルタナ　ファルマ　アクチエンゲゼルシャフト シクレソニドとグリコピロニウムとの組合せ物
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
US20060239935A1 (en) * 2005-04-23 2006-10-26 Boehringer Ingelheim International Gmbh Compositions for inhalation
EP2778064A1 (de) 2013-03-14 2014-09-17 Airbus Operations GmbH Passagierdienste zur Bereitstellung von Transportmitteln
FI3197429T3 (fi) 2014-09-25 2024-06-12 Boehringer Ingelheim Vetmedica Gmbh Yhdistelmähoito sglt2:n estäjillä ja dopamiiniagonisteilla aineenvaihduntahäiriöiden ehkäisemiseksi hevoseläimissä

Also Published As

Publication number Publication date
PT2228064T (pt) 2020-08-25
IL179013A (en) 2012-02-29
NO2014020I2 (de) 2014-08-07
PL1755590T3 (pl) 2012-01-31
CY2020013I2 (el) 2020-11-25
FR20C1018I2 (fr) 2023-11-03
ECSP066950A (es) 2006-12-20
EP2228064A2 (de) 2010-09-15
GB0411056D0 (en) 2004-06-23
SI1755590T1 (sl) 2011-12-30
LTC1755590I2 (lt) 2018-05-10
CY1122863T1 (el) 2020-11-25
LTPA2020509I1 (lt) 2020-07-10
EP1755590B1 (de) 2011-08-24
EP1755590A1 (de) 2007-02-28
US20190282561A1 (en) 2019-09-19
ZA200608123B (en) 2008-07-30
BRPI0511327B8 (pt) 2021-05-25
KR20070011519A (ko) 2007-01-24
US20210236478A1 (en) 2021-08-05
JP2007538036A (ja) 2007-12-27
BRPI0511327B1 (pt) 2019-08-06
SG153836A1 (en) 2009-07-29
KR101360556B1 (ko) 2014-02-21
NO20065787L (no) 2006-12-14
BRPI0511327A (pt) 2007-12-04
FR20C1018I1 (fr) 2020-07-10
ES2775979T3 (es) 2020-07-28
AU2005244439B2 (en) 2009-07-30
US20160101097A1 (en) 2016-04-14
RU2006144810A (ru) 2008-06-27
SE1755590T5 (de) 2015-01-20
TNSN06377A1 (en) 2008-02-22
US20180071276A1 (en) 2018-03-15
US20130237564A1 (en) 2013-09-12
LUC00155I2 (de) 2021-02-17
AU2005244439C1 (en) 2014-09-11
MA28598B1 (fr) 2007-05-02
CA2563302A1 (en) 2005-11-24
ES2370647T3 (es) 2011-12-21
EP2228064B1 (de) 2019-12-11
HUS1400013I1 (hu) 2016-11-28
LTPA2014015I1 (lt) 2014-04-25
DK2228064T3 (da) 2020-03-16
KR101360556B9 (ko) 2022-08-12
KR20130018429A (ko) 2013-02-21
DK1755590T3 (da) 2011-12-12
CN1953745A (zh) 2007-04-25
MXPA06013382A (es) 2007-03-23
CY1112086T1 (el) 2015-11-04
PT1755590E (pt) 2011-10-27
US20080267886A1 (en) 2008-10-30
NO2014020I1 (no) 2014-08-07
NZ550369A (en) 2009-11-27
CA2563302C (en) 2012-08-28
EP2228064A3 (de) 2011-11-02
HK1105579A1 (en) 2008-02-22
JP2012236833A (ja) 2012-12-06
HUE048936T2 (hu) 2020-09-28
CY2020013I1 (el) 2020-11-25
JP5567252B2 (ja) 2014-08-06
AU2005244439A1 (en) 2005-11-24
WO2005110402A1 (en) 2005-11-24
CY2014014I1 (el) 2015-11-04
SI2228064T1 (sl) 2020-04-30
LUC00155I1 (de) 2020-05-27
ATE521348T1 (de) 2011-09-15
LT2228064T (lt) 2020-03-25
EP3603634A1 (de) 2020-02-05
IL179013A0 (en) 2007-05-15
NO334760B1 (no) 2014-05-19
HUS2000014I1 (hu) 2020-07-28
PL2228064T3 (pl) 2020-06-01
LTC2228064I2 (lt) 2022-05-10
RU2388465C2 (ru) 2010-05-10

Similar Documents

Publication Publication Date Title
BE2024C508I2 (de)
BE2022C549I2 (de)
BE2024C511I2 (de)
BE2020C513I2 (de)
BE2020C517I2 (de)
BE2019C540I2 (de)
BE2019C548I2 (de)
BE2018C045I2 (de)
BE2017C027I2 (de)
BE2017C023I2 (de)
BE2017C002I2 (de)
BE2016C067I2 (de)
BE2016C014I2 (de)
BE2015C041I2 (de)
BE2015C038I2 (de)
BE2015C066I2 (de)
BE2015C014I2 (de)
BE2014C071I2 (de)
BE2014C064I2 (de)
BE2014C063I2 (de)
BE2019C535I2 (de)
BE2014C010I2 (de)
BE2013C071I2 (de)
BE2015C065I2 (de)
BE2013C021I2 (de)