CA2064915C
(en)
*
|
1989-08-07 |
2001-05-29 |
Deborah A. Rathjen |
Tumour necrosis factor binding ligands
|
US5959087A
(en)
*
|
1989-08-07 |
1999-09-28 |
Peptide Technology, Ltd. |
Tumour necrosis factor binding ligands
|
US20030225254A1
(en)
*
|
1989-08-07 |
2003-12-04 |
Rathjen Deborah Ann |
Tumour necrosis factor binding ligands
|
US7192584B2
(en)
|
1991-03-18 |
2007-03-20 |
Centocor, Inc. |
Methods of treating psoriasis with anti-TNF antibodies
|
US6270766B1
(en)
|
1992-10-08 |
2001-08-07 |
The Kennedy Institute Of Rheumatology |
Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
|
ZA95960B
(en)
*
|
1994-03-14 |
1995-10-10 |
Genetics Inst |
Use of interleukin-12 antagonists in the treatment of autoimmune diseases
|
US6830751B1
(en)
|
1994-03-14 |
2004-12-14 |
Genetics Institute, Llc |
Use of IL-12 antagonists in the treatment of rheumatoid arthritis
|
US20010055581A1
(en)
|
1994-03-18 |
2001-12-27 |
Lawrence Tamarkin |
Composition and method for delivery of biologically-active factors
|
US6090382A
(en)
*
|
1996-02-09 |
2000-07-18 |
Basf Aktiengesellschaft |
Human antibodies that bind human TNFα
|
BRPI9715219B8
(pt)
*
|
1996-02-09 |
2015-07-07 |
Abbvie Biotechnology Ltd |
Vetor recombinante de expressão, e célula hospedeira procariótica.
|
US7129061B1
(en)
*
|
1996-08-07 |
2006-10-31 |
Biogen Idec Ma Inc. |
Tumor necrosis factor related ligand
|
AU7266698A
(en)
*
|
1997-04-30 |
1998-11-24 |
Enzon, Inc. |
Polyalkylene oxide-modified single chain polypeptides
|
US20040009166A1
(en)
*
|
1997-04-30 |
2004-01-15 |
Filpula David R. |
Single chain antigen-binding polypeptides for polymer conjugation
|
US7229841B2
(en)
|
2001-04-30 |
2007-06-12 |
Cytimmune Sciences, Inc. |
Colloidal metal compositions and methods
|
US6407218B1
(en)
|
1997-11-10 |
2002-06-18 |
Cytimmune Sciences, Inc. |
Method and compositions for enhancing immune response and for the production of in vitro mabs
|
US7067144B2
(en)
*
|
1998-10-20 |
2006-06-27 |
Omeros Corporation |
Compositions and methods for systemic inhibition of cartilage degradation
|
US7553487B2
(en)
|
1998-12-14 |
2009-06-30 |
Genetics Institute, Llc |
Method and compositions for treating asthma
|
AU780031B2
(en)
|
1998-12-14 |
2005-02-24 |
Genetics Institute, Llc |
Cytokine receptor chain
|
DK1159003T3
(da)
*
|
1999-03-02 |
2011-02-07 |
Centocor Inc |
Anti-tnfalfa-antistoffer til terapi af steroid-resistent astma
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
US20040220103A1
(en)
|
1999-04-19 |
2004-11-04 |
Immunex Corporation |
Soluble tumor necrosis factor receptor treatment of medical disorders
|
CA2386230C
(en)
*
|
1999-10-06 |
2009-05-05 |
Basf Aktiengesellschaft |
Modulators of cytokine mediated signalling pathways and integrin .alpha.v.beta.3 receptor antagonists for combination therapy
|
CA2399148A1
(en)
|
2000-02-10 |
2001-08-16 |
Abbott Laboratories |
Antibodies that bind human interleukin-18 and methods of making and using
|
GB0013810D0
(en)
|
2000-06-06 |
2000-07-26 |
Celltech Chiroscience Ltd |
Biological products
|
EP2386575A3
(en)
|
2000-06-29 |
2011-11-30 |
Abbott Laboratories |
Dual specificity antibodies and methods of making and using
|
UA81743C2
(uk)
*
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
US20050196755A1
(en)
*
|
2000-11-17 |
2005-09-08 |
Maurice Zauderer |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
AU2002231736A1
(en)
|
2000-12-22 |
2002-07-08 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Use of repulsive guidance molecule (rgm) and its modulators
|
US20090137416A1
(en)
|
2001-01-16 |
2009-05-28 |
Regeneron Pharmaceuticals, Inc. |
Isolating Cells Expressing Secreted Proteins
|
WO2002057423A2
(en)
*
|
2001-01-16 |
2002-07-25 |
Regeneron Pharmaceuticals, Inc. |
Isolating cells expressing secreted proteins
|
MXPA03008454A
(es)
|
2001-03-22 |
2004-06-30 |
Abbott Gmbh & Co Kg |
Animales transgenicos que expresan anticuerpos especificos para genes de interes y usos de los mismos.
|
US6410955B1
(en)
*
|
2001-04-19 |
2002-06-25 |
Micron Technology, Inc. |
Comb-shaped capacitor for use in integrated circuits
|
CA2817619A1
(en)
*
|
2001-06-08 |
2002-12-08 |
Abbott Laboratories (Bermuda) Ltd. |
Methods of administering anti-tnf.alpha. antibodies
|
NZ530765A
(en)
|
2001-06-26 |
2006-11-30 |
Amgen Fremont Inc |
Antibodies that bind OPGL and compositions and methods for the treatment of bone diseases
|
AU2002316384A1
(en)
*
|
2001-06-26 |
2003-03-03 |
Photomed Technologies, Inc. |
Multiple wavelength illuminator
|
US20050271663A1
(en)
*
|
2001-06-28 |
2005-12-08 |
Domantis Limited |
Compositions and methods for treating inflammatory disorders
|
TWI327597B
(en)
|
2001-08-01 |
2010-07-21 |
Centocor Inc |
Anti-tnf antibodies, compositions, methods and uses
|
AU2002341766A1
(en)
*
|
2001-09-20 |
2003-04-01 |
Genstar Therapeutics Corporation |
Improved methods for treatment with viral vectors
|
US20030065382A1
(en)
*
|
2001-10-02 |
2003-04-03 |
Fischell Robert E. |
Means and method for the treatment of coronary artery obstructions
|
ES2629395T3
(es)
|
2001-10-04 |
2017-08-09 |
Genetics Institute, Llc |
Métodos y composiciones para modular la actividad de la interleucina-21
|
WO2003083071A2
(en)
*
|
2002-03-26 |
2003-10-09 |
Centocor, Inc. |
Diabetes-related immunoglobulin derived proteins, compositions, methods and uses
|
US20030206898A1
(en)
*
|
2002-04-26 |
2003-11-06 |
Steven Fischkoff |
Use of anti-TNFalpha antibodies and another drug
|
US20040009172A1
(en)
*
|
2002-04-26 |
2004-01-15 |
Steven Fischkoff |
Use of anti-TNFalpha antibodies and another drug
|
US20090280065A1
(en)
*
|
2006-04-10 |
2009-11-12 |
Willian Mary K |
Uses and Compositions for Treatment of Psoriasis
|
CA2800126A1
(en)
*
|
2002-07-19 |
2004-01-29 |
Abbott Biotechnology Ltd. |
Treatment of tnf.alpha. related disorders
|
US20040033228A1
(en)
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
US20040091490A1
(en)
*
|
2002-08-28 |
2004-05-13 |
Robert Johnson |
Stable pH optimized formulation of a modified antibody
|
MY150740A
(en)
*
|
2002-10-24 |
2014-02-28 |
Abbvie Biotechnology Ltd |
Low dose methods for treating disorders in which tnf? activity is detrimental
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
EP2258392A1
(en)
*
|
2002-11-08 |
2010-12-08 |
Ablynx N.V. |
Method of administering therapeutic polypeptides
|
US20040101939A1
(en)
*
|
2002-11-22 |
2004-05-27 |
Santora Ling C. |
Method for reducing or preventing modification of a polypeptide in solution
|
US20040162414A1
(en)
*
|
2002-11-22 |
2004-08-19 |
Santora Ling C. |
Method for reducing or preventing modification of a polypeptide in solution
|
MXPA05005921A
(es)
*
|
2002-12-02 |
2005-10-19 |
Abgenix Inc |
Anticuerpos dirigidos a factor de necrosis tumoral y sus usos.
|
WO2004060911A2
(en)
*
|
2002-12-30 |
2004-07-22 |
Amgen Inc. |
Combination therapy with co-stimulatory factors
|
WO2004063335A2
(en)
*
|
2003-01-08 |
2004-07-29 |
Applied Molecular Evolution |
TNF-α BINDING MOLECULES
|
US7101978B2
(en)
*
|
2003-01-08 |
2006-09-05 |
Applied Molecular Evolution |
TNF-α binding molecules
|
NZ540771A
(en)
*
|
2003-01-10 |
2009-05-31 |
Ablynx Nv |
Recombinant VHH single domain antibody from camelidae against von willebrand factor (vWF) or against collagen
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
KR20050119120A
(ko)
*
|
2003-03-14 |
2005-12-20 |
와이어쓰 |
인간 ⅰl-21 수용체에 대한 항체 및 그것의 용도
|
EP1460088A1
(en)
|
2003-03-21 |
2004-09-22 |
Biotest AG |
Humanized anti-CD4 antibody with immunosuppressive properties
|
WO2004098578A2
(en)
*
|
2003-05-12 |
2004-11-18 |
Altana Pharma Ag |
Composition comprising a pde4 inhibitor and a tnf-alfa antagonist selected from infliximab, adalimumab, cdp870 and cdp517
|
FR2856075B1
(fr)
*
|
2003-06-16 |
2007-10-12 |
Monoclonal Antibodies Therapeu |
Procede essentiellement automatise de criblage a grande echelle de cellules secretant des anticorps monoclonaux
|
FR2859725B1
(fr)
*
|
2003-09-16 |
2006-03-10 |
Neovacs |
Procede a haut rendement pour l'obtention d'anticorps humains neutralisant l'activite biologique d'une cytokine humaine
|
US20050100965A1
(en)
|
2003-11-12 |
2005-05-12 |
Tariq Ghayur |
IL-18 binding proteins
|
KR100772800B1
(ko)
*
|
2003-11-17 |
2007-11-01 |
주식회사유한양행 |
인간 종양괴사인자 α를 인식하는 단일클론항체의가변영역 및 이를 코딩하는 유전자
|
EP1694301A4
(en)
|
2003-12-02 |
2009-11-18 |
Cytimmune Sciences Inc |
METHOD AND COMPOSITIONS FOR THE PRODUCTION OF MONOCLONAL ANTIBODIES
|
RU2487887C2
(ru)
|
2003-12-23 |
2013-07-20 |
Дженентек, Инк. |
Новые анти-il 13 антитела и их использование
|
US7435799B2
(en)
*
|
2004-01-08 |
2008-10-14 |
Applied Molecular Evolution |
TNF-α binding molecules
|
US20050260679A1
(en)
*
|
2004-03-19 |
2005-11-24 |
Sirid-Aimee Kellerman |
Reducing the risk of human anti-human antibodies through V gene manipulation
|
US7625549B2
(en)
*
|
2004-03-19 |
2009-12-01 |
Amgen Fremont Inc. |
Determining the risk of human anti-human antibodies in transgenic mice
|
TW201705980A
(zh)
|
2004-04-09 |
2017-02-16 |
艾伯維生物技術有限責任公司 |
用於治療TNFα相關失調症之多重可變劑量療法
|
CN100427504C
(zh)
*
|
2004-06-02 |
2008-10-22 |
北京天广实生物技术有限公司 |
TNFα高亲和力嵌合抗体及其用途
|
US7501121B2
(en)
|
2004-06-17 |
2009-03-10 |
Wyeth |
IL-13 binding agents
|
AR049390A1
(es)
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
Anticuerpos contra la interleuquina-13 humana y usos de los mismos
|
GB0414054D0
(en)
|
2004-06-23 |
2004-07-28 |
Owen Mumford Ltd |
Improvements relating to automatic injection devices
|
EP1773394A2
(en)
*
|
2004-08-05 |
2007-04-18 |
Wyeth a Corporation of the State of Delaware |
Antagonizing interleukin-21 receptor activity
|
WO2006041970A2
(en)
*
|
2004-10-08 |
2006-04-20 |
Abbott Biotechnology Ltd. |
Treatment of respiratory syncytial virus (rsv) infection
|
CN101048426A
(zh)
*
|
2004-10-22 |
2007-10-03 |
金克克国际有限公司 |
分离人抗体
|
AU2005306399B2
(en)
|
2004-11-19 |
2012-02-09 |
Biogen Ma Inc. |
Treatment for multiple sclerosis
|
CN104177497B
(zh)
|
2005-02-08 |
2018-01-16 |
根茨美公司 |
针对TGFβ的抗体
|
AR052289A1
(es)
*
|
2005-02-14 |
2007-03-07 |
Wyeth Corp |
Anticuerpos para interleucina-17f y otros antagonistas de la senalizacion de il-17f y sus usos
|
US7704503B2
(en)
*
|
2005-02-14 |
2010-04-27 |
Wyeth Llc |
Use of IL-17F in diagnosis and therapy of airway inflammation
|
EP2529619B1
(en)
|
2005-02-17 |
2015-09-23 |
Biogen MA Inc. |
Treating neurological disorders
|
GT200600148A
(es)
*
|
2005-04-14 |
2006-11-22 |
|
Metodos para el tratamiento y la prevencion de fibrosis
|
EP1885388B1
(en)
|
2005-05-10 |
2013-09-11 |
Biogen Idec MA Inc. |
Treating and evaluating inflammatory disorders
|
AU2012254978C1
(en)
*
|
2005-05-16 |
2017-06-01 |
Abbvie Biotechnology Ltd |
Use of TNF inhibitor for treatment of erosive polyarthritis
|
TWI399384B
(zh)
*
|
2005-05-16 |
2013-06-21 |
Abbott Biotech Ltd |
TNFα抑制劑於治療侵蝕型多發性關節炎之用途
|
WO2006133287A2
(en)
*
|
2005-06-06 |
2006-12-14 |
Wyeth |
Expression profiles of peripheral blood mononuclear cells for inflammatory bowel diseases
|
PT2390267E
(pt)
|
2005-06-07 |
2013-07-16 |
Esbatech A Novartis Co Llc |
Anticorpos estáveis e solúveis que inibem tnf(alfa)
|
EA012801B1
(ru)
|
2005-06-14 |
2009-12-30 |
Эмджен Инк. |
Самобуферирующиеся композиции белков
|
US20060286108A1
(en)
*
|
2005-06-16 |
2006-12-21 |
Bell Katherine A |
Topical compositions for the treatment of chronic wounds
|
US20080045949A1
(en)
*
|
2005-06-17 |
2008-02-21 |
Hunt Margaret M |
Method of treating degenerative spinal disorders
|
EP1896072A4
(en)
*
|
2005-06-24 |
2013-01-09 |
Univ Duke |
SYSTEM FOR DIRECT HEALTH MANAGEMENT BASED ON HEAT-CONTROLLED BIOPOLYMERS
|
WO2007014162A2
(en)
*
|
2005-07-21 |
2007-02-01 |
Abbott Laboratories |
Multiple gene expression including sorf constructs and methods with polyproteins, pro-proteins, and proteolysis
|
TW200726776A
(en)
*
|
2005-07-29 |
2007-07-16 |
Friedrich Alexander University Of Erlangen Nuremberg |
CD33-specific single-chain immunotoxin and methods of use
|
US20070041905A1
(en)
*
|
2005-08-19 |
2007-02-22 |
Hoffman Rebecca S |
Method of treating depression using a TNF-alpha antibody
|
US20090215992A1
(en)
*
|
2005-08-19 |
2009-08-27 |
Chengbin Wu |
Dual variable domain immunoglobulin and uses thereof
|
EP2500359A3
(en)
|
2005-08-19 |
2012-10-17 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
US7612181B2
(en)
*
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
SG2014010029A
(en)
|
2005-08-19 |
2014-08-28 |
Abbott Lab |
Dual variable domain immunoglobin and uses thereof
|
CN101277974A
(zh)
|
2005-09-30 |
2008-10-01 |
阿伯特有限及两合公司 |
排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
|
WO2007049286A1
(en)
*
|
2005-10-27 |
2007-05-03 |
Tata Memorial Centre |
A system for ex-vivo separation of apoptotic chromatin particles from blood or plasma
|
RS53055B
(en)
|
2005-11-01 |
2014-04-30 |
Abbvie Biotechnology Ltd |
PROCEDURES FOR DETERMINING THE EFFICIENCY OF ADALIMUMAB IN RESPONDENTS WHO HAVE ANKILLOSATIVE SPONDILITIS USING CTX-II AND MMP3 AS BIOMARKERS
|
PE20070684A1
(es)
|
2005-11-14 |
2007-08-06 |
Amgen Inc |
MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
|
CA2631195C
(en)
|
2005-11-30 |
2016-04-05 |
Abbott Laboratories |
Monoclonal antibodies against amyloid beta protein and uses thereof
|
KR20080090408A
(ko)
|
2005-11-30 |
2008-10-08 |
아보트 러보러터리즈 |
항-Aβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법
|
WO2007073486A2
(en)
|
2005-12-20 |
2007-06-28 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
US8841255B2
(en)
*
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
US20130172274A1
(en)
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
NZ569988A
(en)
|
2006-02-01 |
2011-09-30 |
Cephalon Australia Pty Ltd |
Domain antibody construct which binds to human TNF-alpha and contains a modified hinge region sequence and a truncated CH1 domain
|
TW200744634A
(en)
|
2006-02-21 |
2007-12-16 |
Wyeth Corp |
Methods of using antibodies against human IL-22
|
TWI417301B
(zh)
|
2006-02-21 |
2013-12-01 |
Wyeth Corp |
對抗人類介白素-22(il-22)之抗體及其用途
|
EP3088410A3
(en)
|
2006-04-05 |
2016-12-28 |
AbbVie Biotechnology Ltd |
Antibody purification
|
CA2564435A1
(en)
|
2006-04-10 |
2007-10-10 |
Abbott Biotechnology Ltd. |
Methods for monitoring and treating intestinal disorders
|
US9605064B2
(en)
*
|
2006-04-10 |
2017-03-28 |
Abbvie Biotechnology Ltd |
Methods and compositions for treatment of skin disorders
|
US20080118496A1
(en)
*
|
2006-04-10 |
2008-05-22 |
Medich John R |
Uses and compositions for treatment of juvenile rheumatoid arthritis
|
WO2007120626A2
(en)
*
|
2006-04-10 |
2007-10-25 |
Abbott Biotechnology Ltd. |
Uses and compositions for treatment of ankylosing spondylitis
|
EP2666479A3
(en)
|
2006-04-10 |
2014-03-26 |
Abbott Biotechnology Ltd |
Uses and compositions for treatment of juvenile rheumatoid arthritis
|
EP2666472A3
(en)
|
2006-04-10 |
2014-04-02 |
Abbott Biotechnology Ltd |
Uses and compositions for treatment of psoriatic arthritis
|
US9399061B2
(en)
|
2006-04-10 |
2016-07-26 |
Abbvie Biotechnology Ltd |
Methods for determining efficacy of TNF-α inhibitors for treatment of rheumatoid arthritis
|
US20090317399A1
(en)
*
|
2006-04-10 |
2009-12-24 |
Pollack Paul F |
Uses and compositions for treatment of CROHN'S disease
|
US20080131374A1
(en)
*
|
2006-04-19 |
2008-06-05 |
Medich John R |
Uses and compositions for treatment of rheumatoid arthritis
|
US20100021451A1
(en)
|
2006-06-08 |
2010-01-28 |
Wong Robert L |
Uses and compositions for treatment of ankylosing spondylitis
|
US20080311043A1
(en)
*
|
2006-06-08 |
2008-12-18 |
Hoffman Rebecca S |
Uses and compositions for treatment of psoriatic arthritis
|
EP2043711A4
(en)
|
2006-06-30 |
2017-08-30 |
AbbVie Biotechnology Ltd |
Automatic injection device
|
WO2008127271A2
(en)
|
2006-09-08 |
2008-10-23 |
Abbott Laboratories |
Interleukin -13 binding proteins
|
CA2842966A1
(en)
|
2006-09-13 |
2008-03-20 |
Abbvie Inc. |
Cell culture improvements
|
EP2500415A1
(en)
|
2006-09-13 |
2012-09-19 |
Abbott Laboratories |
Cell culture improvements
|
US8911964B2
(en)
|
2006-09-13 |
2014-12-16 |
Abbvie Inc. |
Fed-batch method of making human anti-TNF-alpha antibody
|
SG176427A1
(en)
|
2006-10-27 |
2011-12-29 |
Abbott Biotech Ltd |
Crystalline anti-htnfalpha antibodies
|
JP2010510224A
(ja)
|
2006-11-17 |
2010-04-02 |
アボット・ラボラトリーズ |
ケモカイン受容体拮抗薬としてのアミノピロリジン類
|
ES2432173T3
(es)
|
2006-11-21 |
2013-12-02 |
Kalobios Pharmaceuticals, Inc. |
Métodos de tratamiento de enfermedades inflamatorias crónicas usando un antagonista de GM-CSF
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
EP2114443A4
(en)
|
2006-12-29 |
2011-08-10 |
Abbott Lab |
IL-1A / IL-1B ANTIBODY WITH DOUBLE SPECIFICITY
|
KR20090100461A
(ko)
|
2007-01-16 |
2009-09-23 |
아보트 러보러터리즈 |
건선의 치료방법
|
JP2008209378A
(ja)
*
|
2007-01-31 |
2008-09-11 |
Fujifilm Corp |
バイオセンサー基板
|
WO2008097525A2
(en)
|
2007-02-05 |
2008-08-14 |
Potentia Pharmaceuticals, Inc. |
Local complement inhibition for treatment of complement-mediated disorders
|
WO2008104386A2
(en)
|
2007-02-27 |
2008-09-04 |
Abbott Gmbh & Co. Kg |
Method for the treatment of amyloidoses
|
CN103275216B
(zh)
*
|
2007-03-12 |
2015-05-06 |
艾斯巴技术-诺华有限责任公司 |
单链抗体的基于序列的工程改造和最优化
|
TW200902064A
(en)
*
|
2007-03-28 |
2009-01-16 |
Wyeth Corp |
Methods and compositions for modulating IL-17F/IL-17A biological activity
|
US7807168B2
(en)
*
|
2007-04-10 |
2010-10-05 |
Vaccinex, Inc. |
Selection of human TNFα specific antibodies
|
WO2008124858A2
(en)
*
|
2007-04-11 |
2008-10-23 |
F-Star Biotechnologische Forschungs- Und Entwicklungsges. M.B.H. |
Targeted receptor
|
US8092998B2
(en)
*
|
2007-05-31 |
2012-01-10 |
Abbott Laboratories |
Biomarkers predictive of the responsiveness to TNFα inhibitors in autoimmune disorders
|
EP2152318A4
(en)
*
|
2007-06-01 |
2011-12-07 |
Abbott Biotech Ltd |
COMPOSITIONS AND USES FOR THE TREATMENT OF PSORIASIS AND CROHN'S DISEASE
|
CA2688433A1
(en)
*
|
2007-06-06 |
2008-12-11 |
Domantis Limited |
Methods for selecting protease resistant polypeptides
|
SG182170A1
(en)
*
|
2007-06-06 |
2012-07-30 |
Domantis Ltd |
Polypeptides, antibody variable domains and antagonists
|
WO2008154543A2
(en)
|
2007-06-11 |
2008-12-18 |
Abbott Biotechnology Ltd. |
Methods for treating juvenile idiopathic arthritis
|
US20080311119A1
(en)
|
2007-06-14 |
2008-12-18 |
Biogen Idec Ma Inc. |
Antibody formulations
|
JP5506670B2
(ja)
*
|
2007-06-25 |
2014-05-28 |
エスバテック − ア ノバルティス カンパニー エルエルシー |
単鎖抗体の配列に基づくエンジニアリング及び最適化
|
RU2540150C2
(ru)
|
2007-06-25 |
2015-02-10 |
Эсбатек, Эн Элкон Биомедикал Рисёрч Юнит Ллк |
Способы модификации антител и модифицированные антитела с улучшенными функциональными свойствами
|
US20090110679A1
(en)
*
|
2007-07-13 |
2009-04-30 |
Luk-Chiu Li |
Methods and compositions for pulmonary administration of a TNFa inhibitor
|
WO2009020654A1
(en)
|
2007-08-08 |
2009-02-12 |
Abbott Laboratories |
Compositions and methods for crystallizing antibodies
|
AU2008289441A1
(en)
|
2007-08-22 |
2009-02-26 |
Cytomx Therapeutics, Inc. |
Activatable binding polypeptides and methods of identification and use thereof
|
MX2010002269A
(es)
*
|
2007-08-28 |
2010-03-25 |
Abbott Biotech Ltd |
Composiciones y metodos que comprenden proteinas de union para adalimumab.
|
JP2010540534A
(ja)
|
2007-09-28 |
2010-12-24 |
イントレキソン コーポレーション |
生体治療分子の発現のための治療遺伝子スイッチ構築物およびバイオリアクター、ならびにその使用
|
JP2009082033A
(ja)
*
|
2007-09-28 |
2009-04-23 |
Kaneka Corp |
完全ヒト型抗体生産法
|
CA2706700A1
(en)
|
2007-11-08 |
2009-05-14 |
Cytimmune Sciences, Inc. |
Compositions and methods for generating antibodies
|
NZ602498A
(en)
|
2007-11-30 |
2014-08-29 |
Abbvie Inc |
Protein formulations and methods of making same
|
US8883146B2
(en)
|
2007-11-30 |
2014-11-11 |
Abbvie Inc. |
Protein formulations and methods of making same
|
JP2011510267A
(ja)
*
|
2008-01-03 |
2011-03-31 |
アボツト・バイオテクノロジー・リミテツド |
乾癬の治療における化合物の長期的効力の予測
|
KR20100120289A
(ko)
|
2008-01-15 |
2010-11-15 |
애보트 게엠베하 운트 콤파니 카게 |
분말상 단백질 조성물 및 이의 제조 방법
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
MX2010010028A
(es)
|
2008-03-13 |
2011-08-17 |
Biotest Ag |
Agente para tratar enfermedad.
|
MX2010010026A
(es)
|
2008-03-13 |
2011-03-21 |
Biotest Ag |
Agente para tratar enfermedad.
|
AU2009224690B2
(en)
|
2008-03-13 |
2014-10-09 |
Biotest Ag |
Agent for treating disease
|
CA2717569A1
(en)
|
2008-03-18 |
2009-09-24 |
Abbott Laboratories |
Methods for treating psoriasis
|
US9029508B2
(en)
|
2008-04-29 |
2015-05-12 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
EP2113568A1
(en)
|
2008-04-30 |
2009-11-04 |
Deutsches Rheuma-Forschungszentrum Berlin |
Knock-in mouse for modelling blockade of human TNFalpha
|
NZ588713A
(en)
|
2008-05-09 |
2012-10-26 |
Abbott Gmbh & Co Kg |
Antibodies to receptor of advanced glycation end products (rage) and uses thereof
|
CN102036683A
(zh)
*
|
2008-05-20 |
2011-04-27 |
株式会社钟化 |
细胞毒性组合物
|
SG191639A1
(en)
*
|
2008-06-03 |
2013-07-31 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
WO2009149185A2
(en)
|
2008-06-03 |
2009-12-10 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
SI2307457T2
(sl)
|
2008-06-25 |
2022-10-28 |
Novartis Ag |
Stabilna in topna protitelesa, ki inhibirajo TNF
|
CA2728829C
(en)
|
2008-06-25 |
2018-01-02 |
Esbatech, An Alcon Biomedical Research Unit Llc |
Solubility optimization of immunobinders
|
CA3020290A1
(en)
|
2008-06-25 |
2009-12-30 |
Esbatech, An Alcon Biomedical Research Unit Llc |
Stable and soluble antibodies inhibiting vegf
|
CA2726894A1
(en)
|
2008-06-27 |
2009-12-30 |
Duke University |
Therapeutic agents comprising elastin-like peptides
|
CA2729810A1
(en)
*
|
2008-07-02 |
2010-01-07 |
Emergent Product Development Seattle, Llc |
Tgf-.beta. antagonist multi-target binding proteins
|
SG192496A1
(en)
|
2008-07-08 |
2013-08-30 |
Abbott Lab |
Prostaglandin e2 binding proteins and uses thereof
|
CN102149825B
(zh)
|
2008-07-08 |
2015-07-22 |
Abbvie公司 |
前列腺素e2双重可变结构域免疫球蛋白及其用途
|
CA2735155A1
(en)
*
|
2008-08-28 |
2010-03-04 |
Wyeth Llc |
Uses of il-22, il-17, and il-1 family cytokines in autoimmune diseases
|
CA2739794A1
(en)
*
|
2008-10-07 |
2010-04-15 |
National Cheng Kung University |
Use of il-20 antagonists for treating rheumatoid arthritis and osteoporosis
|
CN118324847A
(zh)
|
2008-10-29 |
2024-07-12 |
阿布林克斯公司 |
单域抗原结合性分子的纯化方法
|
CN102271707B
(zh)
|
2008-10-29 |
2015-04-08 |
阿布林克斯公司 |
单域抗原结合性分子的制剂
|
US8415291B2
(en)
|
2008-10-31 |
2013-04-09 |
Centocor Ortho Biotech Inc. |
Anti-TNF alpha fibronectin type III domain based scaffold compositions, methods and uses
|
CN101419224B
(zh)
*
|
2008-11-06 |
2012-08-22 |
复旦大学附属华山医院 |
一种同时测定人血浆中霉酚酸酯、霉酚酸及其代谢物的方法
|
KR20110096553A
(ko)
*
|
2008-11-28 |
2011-08-30 |
아보트 러보러터리즈 |
안정한 항체 조성물 및 이의 안정화 방법
|
CN101766602B
(zh)
*
|
2008-12-30 |
2012-01-11 |
中国医学科学院血液病医院(血液学研究所) |
取代芳香基腙类化合物在作为肿瘤坏死因子抑制剂药物方面的应用
|
KR20110110247A
(ko)
|
2008-12-30 |
2011-10-06 |
센토코 오르토 바이오테크 인코포레이티드 |
강직성 척추염 환자에서 항-TNFα 항체에 대한 임상적 반응을 예측하는 혈청 마커
|
AU2010203353B2
(en)
|
2009-01-12 |
2016-06-16 |
Cytomx Therapeutics, Inc |
Modified antibody compositions, methods of making and using thereof
|
JP5861223B2
(ja)
|
2009-02-23 |
2016-02-16 |
サイトムエックス セラピューティクス, インク.CytomX Therapeutics, Inc. |
プロタンパク質およびその使用方法
|
US8030026B2
(en)
|
2009-02-24 |
2011-10-04 |
Abbott Laboratories |
Antibodies to troponin I and methods of use thereof
|
PE20160651A1
(es)
|
2009-03-05 |
2016-07-24 |
Abbvie Inc |
Proteinas de union a il-17
|
AU2010236256C1
(en)
|
2009-04-16 |
2015-10-22 |
Abbvie Biotherapeutics Inc. |
Anti-TNF-alpha antibodies and their uses
|
CN101875694B
(zh)
*
|
2009-04-28 |
2014-04-02 |
中国医学科学院基础医学研究所 |
TNFα的抗体及其用途
|
AU2010242972B2
(en)
|
2009-04-29 |
2015-07-09 |
Abbvie Biotechnology Ltd |
Automatic injection device
|
SG175188A1
(en)
*
|
2009-05-04 |
2011-11-28 |
Abbott Biotech Ltd |
Stable high protein concentration formulations of human anti-tnf-alpha-antibodies
|
WO2010132872A1
(en)
*
|
2009-05-15 |
2010-11-18 |
Novimmune S.A |
Combination therapies and methods using anti-cd3 modulating agents and anti-tnf antagonists
|
UY32808A
(es)
*
|
2009-07-29 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas como dominio variable dual y usos de las mismas
|
US9029505B2
(en)
|
2009-08-14 |
2015-05-12 |
Phasebio Pharmaceuticals, Inc. |
Modified vasoactive intestinal peptides
|
CN102711820A
(zh)
*
|
2009-08-21 |
2012-10-03 |
吉联亚生物科技有限公司 |
治疗肺纤维化疾病的方法和组合物
|
EP2470568A2
(en)
|
2009-08-29 |
2012-07-04 |
Abbott Laboratories |
Therapeutic dll4 binding proteins
|
CN102612524A
(zh)
|
2009-09-01 |
2012-07-25 |
雅培制药有限公司 |
双重可变结构域免疫球蛋白及其用途
|
AU2010291927A1
(en)
*
|
2009-09-14 |
2012-04-12 |
AbbVie Deutschland GmbH & Co. KG |
Methods for treating psoriasis
|
US20110070229A1
(en)
*
|
2009-09-24 |
2011-03-24 |
Xbiotech, Inc. |
Method of selecting a monoclonal antibody for administration
|
CN102597775A
(zh)
|
2009-09-25 |
2012-07-18 |
佐马技术有限公司 |
筛选方法
|
TW201119676A
(en)
|
2009-10-15 |
2011-06-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
MX343328B
(es)
*
|
2009-10-26 |
2016-11-01 |
Nestec Sa |
Analisis para la deteccion de farmacos anti-tnf y anticuerpos.
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
KR20120091251A
(ko)
*
|
2009-10-30 |
2012-08-17 |
아보트 러보러터리즈 |
Sorf 작제물 및 다중 유전자 발현
|
US8420083B2
(en)
|
2009-10-31 |
2013-04-16 |
Abbvie Inc. |
Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
|
WO2011058087A1
(en)
|
2009-11-11 |
2011-05-19 |
Gentian As |
Immunoassay for assessing related analytes of different origin
|
GB0920944D0
(en)
|
2009-11-30 |
2010-01-13 |
Biotest Ag |
Agents for treating disease
|
US8871208B2
(en)
*
|
2009-12-04 |
2014-10-28 |
Abbvie Inc. |
11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and uses thereof
|
DK2510001T3
(en)
|
2009-12-08 |
2016-02-29 |
Abbvie Deutschland |
MONOCLONAL ANTIBODIES AGAINST RGM A PROTEIN USED TO TREAT DEGENERATION OF THE RETINAL NERVE FIBER LAYER
|
NZ627052A
(en)
|
2009-12-15 |
2015-12-24 |
Abbvie Biotechnology Ltd |
Improved firing button for automatic injection device
|
WO2011075578A1
(en)
|
2009-12-16 |
2011-06-23 |
Philip Bosch |
Methods of treating interstitial cystitis
|
USRE49251E1
(en)
|
2010-01-04 |
2022-10-18 |
Mapi Pharma Ltd. |
Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
|
US9096655B2
(en)
|
2010-01-27 |
2015-08-04 |
Tata Memorial Centre |
Method for in-vivo binding of chromatin fragments
|
EP2531613A2
(en)
|
2010-02-02 |
2012-12-12 |
Abbott Biotechnology Ltd. |
Methods and compositions for predicting responsiveness to treatment with tnf-alpha inhibitor
|
CN102167741B
(zh)
*
|
2010-02-25 |
2014-05-14 |
上海百迈博制药有限公司 |
一种全人源抗TNF-α单克隆抗体、其制备方法及用途
|
SG10201501562VA
(en)
|
2010-03-02 |
2015-04-29 |
Abbvie Inc |
Therapeutic dll4 binding proteins
|
EP4450523A2
(en)
|
2010-04-02 |
2024-10-23 |
Amunix Pharmaceuticals, Inc. |
Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same
|
KR20150038556A
(ko)
|
2010-04-07 |
2015-04-08 |
애브비 인코포레이티드 |
TNF-α 결합 단백질
|
MX360403B
(es)
|
2010-04-15 |
2018-10-31 |
Abbvie Inc |
Proteinas de union a amiloide beta.
|
DK2558499T3
(en)
|
2010-04-16 |
2017-07-24 |
Biogen Ma Inc |
Anti-VLA-4 antibodies
|
SG184934A1
(en)
|
2010-04-21 |
2012-11-29 |
Abbott Biotech Ltd |
Wearable automatic injection device for controlled delivery of therapeutic agents
|
PT2571532T
(pt)
|
2010-05-14 |
2017-08-04 |
Abbvie Inc |
Proteínas de ligação a il-1
|
WO2011146727A1
(en)
|
2010-05-19 |
2011-11-24 |
Philip Bosch |
Methods of treating interstitial cystitis
|
WO2011153477A2
(en)
|
2010-06-03 |
2011-12-08 |
Abbott Biotechnology Ltd. |
Uses and compositions for treatment of hidradenitis suppurativa (hs)
|
WO2012006500A2
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
WO2012009705A1
(en)
|
2010-07-15 |
2012-01-19 |
Zyngenia, Inc. |
Ang-2 binding complexes and uses thereof
|
TW201206473A
(en)
|
2010-08-03 |
2012-02-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
EP2603524A1
(en)
|
2010-08-14 |
2013-06-19 |
AbbVie Inc. |
Amyloid-beta binding proteins
|
JP6121903B2
(ja)
|
2010-08-19 |
2017-04-26 |
ゾエティス・ベルジャム・エス・アー |
抗ngf抗体およびその使用
|
AU2011293253B2
(en)
|
2010-08-26 |
2014-12-11 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
UY33679A
(es)
|
2010-10-22 |
2012-03-30 |
Esbatech |
Anticuerpos estables y solubles
|
UA113500C2
(xx)
|
2010-10-29 |
2017-02-10 |
|
Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
|
WO2012058392A1
(en)
|
2010-10-29 |
2012-05-03 |
Abbott Laboratories |
Solid dispersions containing an apoptosis-inducing agent
|
TW201241180A
(en)
*
|
2010-11-02 |
2012-10-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
PL2637690T3
(pl)
|
2010-11-11 |
2017-03-31 |
Abbvie Biotechnology Ltd |
Płynne formulacje zawierające przeciwciało anty-tnf alfa o wysokim stężeniu
|
CA2820618C
(en)
|
2010-11-23 |
2020-04-21 |
Steven Elmore |
Use of sulfonylbenzamide compounds in the treatment of systemic lupus erythematosus, lupus nephritis, or sjogren's syndrome
|
EP2643322B1
(en)
|
2010-11-23 |
2017-08-30 |
Abbvie Inc. |
Salts and crystalline forms of an apoptosis-inducing agent
|
AR084210A1
(es)
|
2010-12-08 |
2013-05-02 |
Abbott Lab |
PROTEINAS DE UNION AL TNF-a
|
US20120275996A1
(en)
|
2010-12-21 |
2012-11-01 |
Abbott Laboratories |
IL-1 Binding Proteins
|
MX2013007332A
(es)
|
2010-12-21 |
2014-01-23 |
Abbvie Inc |
Inmunoglobulinas de dominio variable doble biespecificas de il-1 alfa y beta y su uso.
|
EP2490024A1
(en)
|
2010-12-22 |
2012-08-22 |
Proteomika, S.L. |
Method to optimize the treatment of patients with biological drugs
|
ES2859511T3
(es)
|
2011-01-24 |
2021-10-04 |
Abbvie Biotechnology Ltd |
Extracción de protectores de agujas de jeringas y dispositivos de inyección automática
|
CA2825316C
(en)
|
2011-01-24 |
2020-05-05 |
Abbvie Biotechnology Ltd. |
Automatic injection devices having overmolded gripping surfaces
|
US8992477B2
(en)
|
2011-01-24 |
2015-03-31 |
Elcam Agricultural Cooperative Association Ltd. |
Injector
|
RU2455025C1
(ru)
*
|
2011-02-10 |
2012-07-10 |
Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") |
Способ фармакологической коррекции ишемии конечности смесью растворов гомеопатических разведений
|
EP2683404A4
(en)
|
2011-03-07 |
2014-09-10 |
Univ Tokushima |
METHOD FOR TREATING AMYOTROPHER LATERAL SCLEROSIS
|
US20120233834A1
(en)
|
2011-03-18 |
2012-09-20 |
Abbott Biotechnology Ltd. |
Systems, devices and methods for assembling automatic injection devices and sub-assemblies thereof
|
TWI588156B
(zh)
|
2011-03-28 |
2017-06-21 |
賽諾菲公司 |
具有交叉結合區定向之雙重可變區類抗體結合蛋白
|
WO2012135524A1
(en)
|
2011-03-29 |
2012-10-04 |
Abbott Laboratories |
Improved shroud deployment in automatic injection devices
|
AU2012245211B2
(en)
|
2011-04-21 |
2016-03-10 |
Abbvie Inc. |
Wearable automatic injection device
|
WO2012149197A2
(en)
|
2011-04-27 |
2012-11-01 |
Abbott Laboratories |
Methods for controlling the galactosylation profile of recombinantly-expressed proteins
|
CA2837169C
(en)
|
2011-05-24 |
2021-11-09 |
Zyngenia, Inc. |
Multispecific complexes comprising angiopoietin-2-binding peptide and their uses
|
EP4187248A1
(en)
|
2011-05-31 |
2023-05-31 |
Biogen MA Inc. |
Method of assessing risk of pml
|
EP2717902B1
(en)
|
2011-06-06 |
2018-01-24 |
Phasebio Pharmaceuticals, Inc. |
Use of modified vasoactive intestinal peptides in the treatment of hypertension
|
CN103857411A
(zh)
|
2011-07-13 |
2014-06-11 |
阿布维公司 |
使用抗il-13抗体治疗哮喘的方法和组合物
|
GB201112429D0
(en)
*
|
2011-07-19 |
2011-08-31 |
Glaxo Group Ltd |
Antigen-binding proteins with increased FcRn binding
|
CA2843315A1
(en)
*
|
2011-08-01 |
2013-02-07 |
Avaxia Biologics, Inc. |
Bovine polyclonal antibody specific for human tnf
|
RU2652886C2
(ru)
*
|
2011-10-20 |
2018-05-03 |
ИЭсБиЭйТЕК-Э НОВАРТИС КОМПАНИ ЭлЭлСи |
Стабильные антитела, связывающиеся с несколькими антигенами
|
AR088512A1
(es)
|
2011-10-24 |
2014-06-18 |
Abbvie Inc |
Anticuerpos dirigidos contra el tnf
|
CA2853258A1
(en)
|
2011-10-24 |
2013-05-02 |
Abbvie Inc. |
Immunobinders directed against sclerostin
|
CN104185641A
(zh)
|
2011-10-24 |
2014-12-03 |
艾伯维公司 |
针对tnf和il-17的双特异性免疫结合剂
|
WO2013080050A2
(en)
|
2011-11-30 |
2013-06-06 |
Universitaetsklinikum Erlangen |
Methods and compositions for determining responsiveness to treatment with a tnf-alpha inhibitor
|
JP6342812B2
(ja)
|
2011-12-14 |
2018-06-13 |
アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー |
鉄関連障害を診断および治療するための組成物および方法
|
EP2791175A2
(en)
|
2011-12-14 |
2014-10-22 |
Abbvie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
WO2013087911A1
(en)
|
2011-12-16 |
2013-06-20 |
Synthon Biopharmaceuticals B.V. |
Compounds and methods for treating inflammatory diseases
|
WO2013101972A2
(en)
|
2011-12-30 |
2013-07-04 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
TW201333035A
(zh)
|
2011-12-30 |
2013-08-16 |
Abbvie Inc |
針對il-13及/或il-17之雙特異性結合蛋白
|
NZ625403A
(en)
|
2012-01-27 |
2016-03-31 |
Abbvie Inc |
Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
|
EP2822591B1
(en)
|
2012-03-07 |
2018-05-02 |
Cadila Healthcare Limited |
Pharmaceutical formulations of tnf-alpha antibodies
|
WO2013158273A1
(en)
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Methods to modulate c-terminal lysine variant distribution
|
US9150645B2
(en)
|
2012-04-20 |
2015-10-06 |
Abbvie, Inc. |
Cell culture methods to reduce acidic species
|
US9067990B2
(en)
|
2013-03-14 |
2015-06-30 |
Abbvie, Inc. |
Protein purification using displacement chromatography
|
EP2657334B1
(en)
|
2012-04-26 |
2016-07-06 |
GeneFrontier Corporation |
Efficient method for displaying protein multimer
|
US9249182B2
(en)
|
2012-05-24 |
2016-02-02 |
Abbvie, Inc. |
Purification of antibodies using hydrophobic interaction chromatography
|
CA2875783C
(en)
|
2012-06-06 |
2018-12-11 |
Zoetis Llc |
Caninized anti-ngf antibodies and methods thereof
|
SG11201408161RA
(en)
|
2012-06-08 |
2015-01-29 |
Sutro Biopharma Inc |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
TW201402608A
(zh)
|
2012-07-12 |
2014-01-16 |
Abbvie Inc |
Il-1結合蛋白質
|
DK3584255T3
(da)
|
2012-08-31 |
2022-04-04 |
Sutro Biopharma Inc |
Modificerede aminosyrer omfattende en azidogruppe
|
US9512214B2
(en)
|
2012-09-02 |
2016-12-06 |
Abbvie, Inc. |
Methods to control protein heterogeneity
|
KR20150043523A
(ko)
|
2012-09-02 |
2015-04-22 |
애브비 인코포레이티드 |
단백질 불균일성의 제어 방법
|
AU2013312300A1
(en)
|
2012-09-07 |
2015-04-16 |
Coherus Biosciences, Inc. |
Stable aqueous formulations of adalimumab
|
EP2897978B1
(en)
*
|
2012-09-19 |
2017-03-22 |
AbbVie Biotherapeutics Inc. |
Methods for identifying antibodies with reduced immunogenicity
|
US20140161817A1
(en)
|
2012-11-01 |
2014-06-12 |
Michael Siedler |
Stable dual variable domain immunoglobulin protein formulations
|
SG11201503412RA
(en)
|
2012-11-01 |
2015-05-28 |
Abbvie Inc |
Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
|
TW202423993A
(zh)
|
2012-11-14 |
2024-06-16 |
美商再生元醫藥公司 |
重組細胞表面捕捉蛋白質
|
US9550986B2
(en)
|
2012-12-21 |
2017-01-24 |
Abbvie Inc. |
High-throughput antibody humanization
|
US9856319B2
(en)
|
2012-12-28 |
2018-01-02 |
Abbvie Inc. |
Monovalent binding proteins
|
EP2938634A2
(en)
|
2012-12-28 |
2015-11-04 |
AbbVie Inc. |
Dual specific binding proteins having a receptor sequence
|
CN104955480A
(zh)
|
2013-01-25 |
2015-09-30 |
西蒙有限公司 |
用于选择性减少循环的生物活性可溶性tnf的组合物以及用于治疗tnf介导的疾病的方法
|
KR20160002713A
(ko)
*
|
2013-02-13 |
2016-01-08 |
라보라토이레 프란카이즈 듀 프락티온네먼트 에트 데스 바이오테크놀로지스 |
고도로 갈락토실화된 항-tnf-알파 항체 및 이의 용도
|
EP2830651A4
(en)
|
2013-03-12 |
2015-09-02 |
Abbvie Inc |
HUMAN ANTIBODIES THAT BIND TNF-ALPHA AND PREPARATION METHODS
|
US20140275082A1
(en)
|
2013-03-14 |
2014-09-18 |
Abbvie Inc. |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
BR112015017307A2
(pt)
|
2013-03-14 |
2017-11-21 |
Abbvie Inc |
composições de espécies com baixa acidez e métodos para produção e uso das mesmas
|
SG11201507365VA
(en)
|
2013-03-14 |
2015-10-29 |
Abbvie Inc |
Low acidic species compositions and methods for producing the same using displacement chromatography
|
US9790478B2
(en)
|
2013-03-14 |
2017-10-17 |
Abbott Laboratories |
HCV NS3 recombinant antigens and mutants thereof for improved antibody detection
|
WO2014158272A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbott Laboratories |
Hcv antigen-antibody combination assay and methods and compositions for use therein
|
US9017687B1
(en)
|
2013-10-18 |
2015-04-28 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same using displacement chromatography
|
US9499614B2
(en)
|
2013-03-14 |
2016-11-22 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
|
CA2906417C
(en)
|
2013-03-14 |
2022-06-21 |
Robert Ziemann |
Hcv core lipid binding domain monoclonal antibodies
|
WO2014159579A1
(en)
*
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
|
BR112015023752B1
(pt)
|
2013-03-15 |
2023-11-14 |
Zyngenia, Inc. |
Domínio de reconhecimento modular (mrd), complexo compreendendo mrd e cetuximabe, usos do complexo para inibir a angiogênese e tratar câncer e composição farmacêutica compreendendo o dito complexo
|
US9062108B2
(en)
|
2013-03-15 |
2015-06-23 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-1 and/or IL-17
|
KR20150131360A
(ko)
|
2013-03-15 |
2015-11-24 |
애브비 인코포레이티드 |
TNFα에 대해 지시된 이원 특이적 결합 단백질
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
US10087248B2
(en)
*
|
2013-05-22 |
2018-10-02 |
Metabolic Engineering Laboratories Co., Ltd. |
Anti-TNF-α/CXCL10 double-targeting antibody and use thereof
|
CA2914566A1
(en)
|
2013-06-07 |
2014-12-11 |
Duke University |
Inhibitors of complement factor h
|
US9764039B2
(en)
|
2013-07-10 |
2017-09-19 |
Sutro Biopharma, Inc. |
Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
WO2015017683A1
(en)
*
|
2013-07-31 |
2015-02-05 |
Malast Mary |
Antimicrobial compositions and methods of use
|
AU2014318615B2
(en)
|
2013-09-13 |
2020-03-12 |
Genentech, Inc. |
Methods and compositions comprising purified recombinant polypeptides
|
KR102332302B1
(ko)
|
2013-09-13 |
2021-12-01 |
제넨테크, 인크. |
세포주에서 숙주 세포 단백질 및 재조합 폴리펩티드 생성물을 검출 및 정량화하기 위한 조성물 및 방법
|
WO2015051293A2
(en)
|
2013-10-04 |
2015-04-09 |
Abbvie, Inc. |
Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
|
EP3052524A2
(en)
|
2013-10-06 |
2016-08-10 |
Abbvie Inc. |
Dual specific binding proteins directed against immune cell receptors and tlr signaling autoantigens
|
US9840493B2
(en)
|
2013-10-11 |
2017-12-12 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
CA2926588C
(en)
|
2013-10-16 |
2020-07-21 |
Oncobiologics, Inc. |
Buffer formulations for enhanced antibody stability
|
US8946395B1
(en)
|
2013-10-18 |
2015-02-03 |
Abbvie Inc. |
Purification of proteins using hydrophobic interaction chromatography
|
US9181337B2
(en)
|
2013-10-18 |
2015-11-10 |
Abbvie, Inc. |
Modulated lysine variant species compositions and methods for producing and using the same
|
US9085618B2
(en)
|
2013-10-18 |
2015-07-21 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same
|
WO2015073884A2
(en)
|
2013-11-15 |
2015-05-21 |
Abbvie, Inc. |
Glycoengineered binding protein compositions
|
WO2015084883A2
(en)
|
2013-12-02 |
2015-06-11 |
Abbvie, Inc. |
Compositions and methods for treating osteoarthritis
|
CN103965357B
(zh)
|
2013-12-31 |
2016-08-17 |
嘉和生物药业有限公司 |
一种抗人rankl抗体
|
US10955422B2
(en)
|
2014-02-27 |
2021-03-23 |
Biogen Ma, Inc. |
Method of assessing risk of PML
|
DK3116891T3
(da)
|
2014-03-10 |
2020-05-04 |
Richter Gedeon Nyrt |
Immunglobulinrensning ved hjælp af forrensningstrin
|
AR099625A1
(es)
*
|
2014-03-21 |
2016-08-03 |
Lilly Co Eli |
Anticuerpos de il-21
|
TWI731535B
(zh)
|
2014-03-21 |
2021-06-21 |
美商艾伯維有限公司 |
抗-egfr抗體及抗體藥物結合物
|
IN2014MU01248A
(nl)
*
|
2014-04-02 |
2015-10-09 |
Intas Pharmaceuticals Ltd |
|
WO2015172046A1
(en)
|
2014-05-08 |
2015-11-12 |
Phasebio Pharmaceuticals, Inc. |
Methods and compositions for treating cystic fibrosis
|
EP2946766B1
(en)
|
2014-05-23 |
2016-03-02 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
LT2946765T
(lt)
|
2014-05-23 |
2016-11-25 |
Ares Trading S.A. |
Skysta farmacinė kompozicija
|
ES2607489T3
(es)
|
2014-05-23 |
2017-03-31 |
Ares Trading S.A. |
Composición farmacéutica líquida
|
FR3022462B1
(fr)
*
|
2014-06-18 |
2018-04-27 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Composition orale d'anticorps anti-tnfalpha
|
EP3145951A1
(en)
|
2014-06-24 |
2017-03-29 |
InSight Biopharmaceuticals Ltd. |
Methods of purifying antibodies
|
JP7037885B2
(ja)
*
|
2014-06-30 |
2022-03-17 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
pH依存性抗原結合を示す抗TNFa抗体
|
US20170226552A1
(en)
|
2014-07-03 |
2017-08-10 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt
|
WO2016007764A1
(en)
|
2014-07-09 |
2016-01-14 |
Abbvie Inc. |
Methods for modulating the glycosylation profile of recombinant proteins using non-commonly used sugars
|
EP3167396B1
(en)
|
2014-07-11 |
2024-01-17 |
Iogenetics, LLC. |
Immune recognition motifs
|
UA123624C2
(uk)
|
2014-09-03 |
2021-05-05 |
Бьорінґер Інґельхайм Інтернаціональ Ґмбх |
Сполука, специфічна до іл-23а та фнп-альфа, та її застосування
|
US10435464B1
(en)
|
2014-09-05 |
2019-10-08 |
Coherus Biosciences, Inc. |
Methods for making recombinant proteins
|
HUP1400510A1
(hu)
|
2014-10-28 |
2016-05-30 |
Richter Gedeon Nyrt |
Gyógyászati TNFalfa ellenes antitest készítmény
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
US20170360929A1
(en)
|
2014-12-23 |
2017-12-21 |
Pfizer Inc. |
Stable aqueous antibody formulation for anti tnf alpha antibodies
|
EP3085709B1
(en)
|
2014-12-28 |
2019-08-21 |
Genor Biopharma Co., Ltd |
Humanized anti-human rankl antibody, pharmaceutical composition and use thereof
|
EP3247718B1
(en)
|
2015-01-21 |
2021-09-01 |
Outlook Therapeutics, Inc. |
Modulation of charge variants in a monoclonal antibody composition
|
EP3053572A1
(en)
|
2015-02-06 |
2016-08-10 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
ES2822598T3
(es)
|
2015-02-09 |
2021-05-04 |
Phasebio Pharmaceuticals Inc |
Métodos y composiciones para tratar enfermedades y trastornos musculares
|
CN105777905B
(zh)
*
|
2015-03-24 |
2019-06-25 |
广东东阳光药业有限公司 |
一种全人源抗TNF-α单克隆抗体及其应用
|
EP3078675A1
(en)
|
2015-04-10 |
2016-10-12 |
Ares Trading S.A. |
Induction dosing regimen for the treatment of tnf alpha mediated disorders
|
WO2016179469A1
(en)
*
|
2015-05-07 |
2016-11-10 |
Abbvie Inc. |
Methods and compositions for diagnosing and treating inflammatory bowel disease
|
DK3303395T3
(da)
|
2015-05-29 |
2020-01-27 |
Abbvie Inc |
Anti-cd40-antistoffer og anvendelser deraf
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
HU231463B1
(hu)
|
2015-08-04 |
2024-01-28 |
Richter Gedeon Nyrt. |
Módszer rekombináns proteinek galaktóz tartalmának növelésére
|
US11583584B1
(en)
|
2015-10-28 |
2023-02-21 |
Coherus Biosciences, Inc. |
Stable protein compositions and methods of their use
|
US11229702B1
(en)
|
2015-10-28 |
2022-01-25 |
Coherus Biosciences, Inc. |
High concentration formulations of adalimumab
|
GB201522394D0
(en)
|
2015-12-18 |
2016-02-03 |
Ucb Biopharma Sprl |
Antibodies
|
MX2018009341A
(es)
|
2016-02-03 |
2019-05-15 |
Oncobiologics Inc |
Formulaciones tamponadas para una mayor estabilidad de anticuerpos.
|
US10465003B2
(en)
|
2016-02-05 |
2019-11-05 |
Janssen Biotech, Inc. |
Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes
|
EP3219726B1
(en)
*
|
2016-03-17 |
2020-12-02 |
Tillotts Pharma AG |
Anti-tnf alpha-antibodies and functional fragments thereof
|
US10774140B2
(en)
|
2016-03-17 |
2020-09-15 |
Numab Therapeutics AG |
Anti-TNFα-antibodies and functional fragments thereof
|
EP3440113A1
(en)
|
2016-04-08 |
2019-02-13 |
Gilead Sciences, Inc. |
Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases
|
WO2017184880A1
(en)
|
2016-04-20 |
2017-10-26 |
Coherus Biosciences, Inc. |
A method of filling a container with no headspace
|
IL297519B2
(en)
|
2016-04-27 |
2024-06-01 |
Abbvie Inc |
Methods for treating diseases in which IL-13 activity is harmful using antibodies to IL-13
|
DK3464318T3
(da)
|
2016-06-02 |
2021-06-28 |
Abbvie Inc |
Glucocorticoidreceptoragonist og immunkonjugater deraf
|
MX2018015274A
(es)
|
2016-06-08 |
2019-10-07 |
Abbvie Inc |
Anticuerpos anti-cd98 y conjugados de anticuerpo y farmaco.
|
US20200338209A1
(en)
|
2016-06-08 |
2020-10-29 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
CN109963870B
(zh)
|
2016-06-08 |
2023-07-28 |
艾伯维公司 |
抗b7-h3抗体和抗体药物偶联物
|
AU2017279539A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-B7-H3 antibodies and antibody drug conjugates
|
AU2017277422A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-EGFR antibody drug conjugates
|
US20190153108A1
(en)
|
2016-06-08 |
2019-05-23 |
Abbvie Inc. |
Anti-egfr antibody drug conjugates
|
EP3472197A1
(en)
|
2016-06-15 |
2019-04-24 |
Sutro Biopharma, Inc. |
Antibodies with engineered ch2 domains, compositions thereof and methods of using the same
|
WO2018018613A1
(zh)
|
2016-07-29 |
2018-02-01 |
广东东阳光药业有限公司 |
一种提高抗体纯度的细胞培养基和培养方法
|
US12097292B2
(en)
|
2016-08-28 |
2024-09-24 |
Mapi Pharma Ltd. |
Process for preparing microparticles containing glatiramer acetate
|
WO2018045258A1
(en)
*
|
2016-09-02 |
2018-03-08 |
The University Of Chicago |
TREATMENT OF TNF-alpha CYTOTOXICITY
|
WO2018050902A2
(en)
*
|
2016-09-15 |
2018-03-22 |
Quadrucept Bio Limited |
Multimers, tetramers & octamers
|
AU2017339809B2
(en)
|
2016-10-03 |
2022-02-17 |
Abbott Laboratories |
Improved methods of assessing UCH-L1 status in patient samples
|
WO2018075408A1
(en)
|
2016-10-17 |
2018-04-26 |
Alexion Pharmaceuticals, Inc. |
Methods of treating acute myeloid leukemia (aml) with combinations of anti-cd200 antibodies, cytarabine, and daunorubicin
|
SG11201903521XA
(en)
|
2016-10-21 |
2019-05-30 |
Amgen Inc |
Pharmaceutical formulations and methods of making the same
|
WO2018102594A1
(en)
|
2016-12-01 |
2018-06-07 |
Alexion Pharmaceuticals, Inc. |
Methods of treating solid tumors with anti-cd200 antibodies
|
CA3044526A1
(en)
|
2016-12-07 |
2018-06-14 |
Progenity, Inc. |
Gastrointestinal tract detection methods, devices and systems
|
KR102616436B1
(ko)
|
2016-12-14 |
2023-12-27 |
비오라 쎄라퓨틱스, 인크. |
Tnf 저해제로의 위장관 질환의 치료
|
US11702481B2
(en)
|
2016-12-16 |
2023-07-18 |
Bluefin Biomedicine, Inc. |
Anti-cub domain-containing protein 1 (CDCP1) antibodies, antibody drug conjugates, and methods of use thereof
|
JOP20190162A1
(ar)
|
2016-12-30 |
2019-06-27 |
Biocad Joint Stock Co |
تركيبة صيدلانية مائية من جسم مضاد لـ tnf? أحادي النسيلة معاود الارتباط الجيني
|
CA3049857A1
(en)
|
2017-01-11 |
2018-07-19 |
Celltrion Inc. |
Stable liquid formulation
|
TW202421659A
(zh)
|
2017-01-20 |
2024-06-01 |
美商健臻公司 |
骨靶向抗體
|
TWI787230B
(zh)
|
2017-01-20 |
2022-12-21 |
法商賽諾菲公司 |
抗TGF-β抗體及其用途
|
JP2020506916A
(ja)
|
2017-01-30 |
2020-03-05 |
ヤンセン バイオテツク,インコーポレーテツド |
活動性乾癬性関節炎の治療のための抗tnf抗体、組成物、及び方法
|
MA47442A
(fr)
|
2017-02-07 |
2019-12-18 |
Janssen Biotech Inc |
Anticorps anti-tnf, compositions et méthodes pour le traitement de la spondylarthrite ankylosante active
|
US11608357B2
(en)
|
2018-08-28 |
2023-03-21 |
Arecor Limited |
Stabilized antibody protein solutions
|
EP3372242A1
(en)
|
2017-03-06 |
2018-09-12 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
EP3372241A1
(en)
|
2017-03-06 |
2018-09-12 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
US11016092B2
(en)
|
2017-03-23 |
2021-05-25 |
Abbott Laboratories |
Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase L1
|
WO2018178973A1
(en)
|
2017-03-26 |
2018-10-04 |
Mapi Pharma Ltd. |
Glatiramer depot systems for treating progressive forms of multiple sclerosis
|
WO2018184692A1
(en)
|
2017-04-07 |
2018-10-11 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
JP7344797B2
(ja)
|
2017-04-15 |
2023-09-14 |
アボット・ラボラトリーズ |
早期バイオマーカーを使用する、ヒト対象における外傷性脳損傷の、超急性の診断及び決定の一助となるための方法
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
US10866251B2
(en)
|
2017-05-25 |
2020-12-15 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
JP7269182B2
(ja)
|
2017-05-30 |
2023-05-08 |
アボット・ラボラトリーズ |
心臓トロポニンi及び早期バイオマーカーを使用する、ヒト対象における軽度外傷性脳損傷を診断及び査定する一助となるための方法
|
WO2019010131A1
(en)
|
2017-07-03 |
2019-01-10 |
Abbott Laboratories |
IMPROVED METHODS FOR MEASURING CARBOXY TERMINATION HYDROLASE LEVELS OF UBIQUITIN L1 IN BLOOD
|
WO2019067499A1
(en)
|
2017-09-27 |
2019-04-04 |
Alexion Pharmaceuticals, Inc. |
BIOMARKER SIGNATURE FOR PREDICTING A TUMOR RESPONSE TO ANTI-CD200 THERAPY
|
RS61994B1
(sr)
|
2017-12-01 |
2021-07-30 |
Abbvie Inc |
Agonist glukokortikoidnog receptora i njegovi imunokonjugati
|
CN109879962B
(zh)
*
|
2017-12-06 |
2022-10-11 |
北京科立思维生物科技有限公司 |
抗tnf单链抗体、抗il-6单链抗体及其融合蛋白及其应用
|
JP7344801B2
(ja)
|
2017-12-09 |
2023-09-14 |
アボット・ラボラトリーズ |
グリア原線維性酸性タンパク質(gfap)及び/又はユビキチンカルボキシ末端ヒドロラーゼl1(uch-l1)を使用する、整形外科損傷を負っており、軽度外傷性脳損傷(tbi)などの頭部への損傷を負ったか又は負った可能性がある対象についての診断及び査定の一助となるための方法
|
US11016105B2
(en)
|
2017-12-09 |
2021-05-25 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of GFAP and UCH-L1
|
WO2019126133A1
(en)
|
2017-12-20 |
2019-06-27 |
Alexion Pharmaceuticals, Inc. |
Liquid formulations of anti-cd200 antibodies
|
WO2019126536A1
(en)
|
2017-12-20 |
2019-06-27 |
Alexion Pharmaceuticals Inc. |
Humanized anti-cd200 antibodies and uses thereof
|
WO2019177690A1
(en)
|
2018-03-12 |
2019-09-19 |
Zoetis Services Llc |
Anti-ngf antibodies and methods thereof
|
US11913951B2
(en)
|
2018-03-26 |
2024-02-27 |
Alexion Pharmaceuticals, Inc. |
High throughput method for measuring the protease activity of complement C3 convertase
|
CN112867394B
(zh)
|
2018-06-04 |
2024-09-13 |
马萨诸塞州渤健公司 |
具有降低的效应功能的抗vla-4抗体
|
EP3810095A1
(en)
|
2018-06-20 |
2021-04-28 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with a tnf inhibitor
|
CN112654350A
(zh)
|
2018-07-03 |
2021-04-13 |
诺华股份有限公司 |
使用nlrp3拮抗剂治疗对tnf抑制剂有抗性的受试者或针对所述患者选择治疗的方法
|
US20210340277A1
(en)
|
2018-10-11 |
2021-11-04 |
The Scripps Research Institute |
Antibody compounds with reactive arginine and related antibody drug conjugates
|
JP2022505562A
(ja)
|
2018-10-24 |
2022-01-14 |
ノバルティス アーゲー |
Nlrp活性に関連する状態を治療するための化合物及び組成物
|
AU2019374190B2
(en)
*
|
2018-11-05 |
2024-02-22 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
Anti-TNFα/anti IL-17A natural antibody structure-like heterodimer form of bispecific antibody and preparation method therefor
|
HU231514B1
(hu)
|
2018-11-07 |
2024-07-28 |
Richter Gedeon Nyrt. |
Sejttenyészetben előállított rekombináns glikoprotein glikozilációs mintázatának megváltoztatására szolgáló módszer
|
CN113015730A
(zh)
|
2018-11-13 |
2021-06-22 |
诺华股份有限公司 |
用于治疗与nlrp活性相关的病症的化合物和组合物
|
JP2022506898A
(ja)
|
2018-11-13 |
2022-01-17 |
ノバルティス アーゲー |
Nlrp活性に関連する状態を処置するための化合物及び組成物
|
EP3883635A1
(en)
|
2018-11-19 |
2021-09-29 |
Progenity, Inc. |
Methods and devices for treating a disease with biotherapeutics
|
US20220098310A1
(en)
|
2018-12-06 |
2022-03-31 |
Alexion Pharmaceuticals, Inc. |
Anti-alk2 antibodies and uses thereof
|
US20230272402A1
(en)
|
2018-12-25 |
2023-08-31 |
Institute Of Basic Medical Sciences Chinese Academy Of Medical Sciences |
Small rna medicament for prevention and treatment of inflammation-related diseases and combination thereof
|
WO2020154321A1
(en)
|
2019-01-22 |
2020-07-30 |
Novartis Inflammasome Research, Inc. |
Compounds and compositions for treating conditions associated with nlrp activity
|
HU231498B1
(hu)
|
2019-04-04 |
2024-05-28 |
Richter Gedeon Nyrt |
Immunglobulinok affinitás kromatográfiájának fejlesztése kötést megelőző flokkulálás alkalmazásával
|
KR102323342B1
(ko)
*
|
2019-04-26 |
2021-11-08 |
주식회사 와이바이오로직스 |
IL-17A 및 TNF-α에 특이적으로 결합하는 이중표적 항체
|
MX2021014302A
(es)
|
2019-05-23 |
2022-01-04 |
Janssen Biotech Inc |
Metodo para tratar la enfermedad inflamatoria del intestino con una terapia de combinacion de anticuerpos contra il-23 y tnf alfa.
|
WO2021002887A1
(en)
|
2019-07-02 |
2021-01-07 |
Novartis Inflammasome Research, Inc. |
Gut-targeted nlrp3 antagonists and their use in therapy
|
WO2021005607A1
(en)
*
|
2019-07-09 |
2021-01-14 |
National Institute For Biotechnology In The Negev Ltd. |
Antibodies with reduced immunogenicity
|
CN115666704A
(zh)
|
2019-12-13 |
2023-01-31 |
比奥拉治疗股份有限公司 |
用于将治疗剂递送至胃肠道的可摄取装置
|
FR3104582A1
(fr)
|
2019-12-17 |
2021-06-18 |
Commissariat A L'energie Atomique Et Aux Energies Alternatives |
Variants de l’adalimumab au potentiel immunogène réduit
|
IL295387A
(en)
|
2020-02-05 |
2022-10-01 |
Larimar Therapeutics Inc |
Peptide-binding proteins and their uses
|
WO2021178597A1
(en)
|
2020-03-03 |
2021-09-10 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use
|
CA3175523A1
(en)
|
2020-04-13 |
2021-10-21 |
Antti Virtanen |
Methods, complexes and kits for detecting or determining an amount of a .beta.-coronavirus antibody in a sample
|
KR20230042301A
(ko)
|
2020-08-04 |
2023-03-28 |
애벗트 라보라토리이즈 |
샘플에서 sars-cov-2 단백질을 검출하기 위한 개선된 방법 및 키트
|
CN111944052B
(zh)
*
|
2020-08-26 |
2022-02-11 |
中国药科大学 |
抗TNF-α/PD-1双特异性抗体及其应用
|
CN112010970B
(zh)
*
|
2020-10-30 |
2021-01-12 |
迈威(上海)生物科技股份有限公司 |
一种去除重组表达抗体聚体和降解产物的方法
|
US20220170948A1
(en)
|
2020-12-01 |
2022-06-02 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a human subject having received a head computerized tomography scan that is negative for a tbi
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
US11672929B2
(en)
|
2020-12-02 |
2023-06-13 |
Breathe Restore, Inc. |
Product delivery devices and methods
|
WO2022123293A1
(ko)
|
2020-12-09 |
2022-06-16 |
에이치케이이노엔 주식회사 |
항 OX40L 항체, 항 OX40L 및 항 TNFα 이중 특이성 항체 및 이들의 용도
|
MX2023007303A
(es)
*
|
2020-12-18 |
2023-09-11 |
Elanco Us Inc |
Anticuerpos tnf alfa y ngf para uso veterinario.
|
WO2022147147A1
(en)
|
2020-12-30 |
2022-07-07 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
WO2022178078A1
(en)
*
|
2021-02-19 |
2022-08-25 |
Theripion, Inc. |
Paraoxonase fusion polypeptides and related compositions and methods
|
WO2022232286A1
(en)
|
2021-04-27 |
2022-11-03 |
Generation Bio Co. |
Non-viral dna vectors expressing anti-coronavirus antibodies and uses thereof
|
JP2024515788A
(ja)
|
2021-04-27 |
2024-04-10 |
ジェネレーション バイオ カンパニー |
治療抗体を発現する非ウイルスdnaベクター及びその使用
|
US20220381796A1
(en)
|
2021-05-18 |
2022-12-01 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
WO2022266034A1
(en)
|
2021-06-14 |
2022-12-22 |
Abbott Laboratories |
Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
|
AU2022298665A1
(en)
*
|
2021-06-22 |
2024-01-04 |
University Of Virginia Patent Foundation |
Compositions and methods for detecting and regulating fibronectin-integrin interactions and signaling
|
WO2023025248A1
(zh)
|
2021-08-26 |
2023-03-02 |
映恩生物制药(苏州)有限公司 |
一种甾体化合物及其缀合物
|
CN118715440A
(zh)
|
2021-08-31 |
2024-09-27 |
雅培实验室 |
诊断脑损伤的方法和系统
|
CA3230038A1
(en)
|
2021-08-31 |
2023-03-09 |
Hongwei Zhang |
Methods and systems of diagnosing brain injury
|
CA3232176A1
(en)
|
2021-09-30 |
2023-04-06 |
Beth MCQUISTON |
Methods and systems of diagnosing brain injury
|
AU2022413677A1
(en)
|
2021-12-17 |
2024-06-27 |
Abbott Laboratories |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
WO2023150652A1
(en)
|
2022-02-04 |
2023-08-10 |
Abbott Laboratories |
Lateral flow methods, assays, and devices for detecting the presence or measuring the amount of ubiquitin carboxy-terminal hydrolase l1 and/or glial fibrillary acidic protein in a sample
|
AU2023235112A1
(en)
|
2022-03-14 |
2024-10-17 |
Generation Bio Co. |
Heterologous prime boost vaccine compositions and methods of use
|
TW202415677A
(zh)
*
|
2022-06-28 |
2024-04-16 |
美商葉達弗生物科學公司 |
抗TNFα抗體及組合物
|
WO2024006876A1
(en)
|
2022-06-29 |
2024-01-04 |
Abbott Laboratories |
Magnetic point-of-care systems and assays for determining gfap in biological samples
|
CN116903738A
(zh)
*
|
2022-08-02 |
2023-10-20 |
北京绿竹生物技术股份有限公司 |
一种低甘露糖型抗人肿瘤坏死因子-α单抗及其用途
|
TW202421172A
(zh)
|
2022-09-07 |
2024-06-01 |
美商Mdx管理有限責任公司 |
用於治療癌症之shp-1抑制劑
|
WO2024059708A1
(en)
|
2022-09-15 |
2024-03-21 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|
WO2024097804A1
(en)
|
2022-11-02 |
2024-05-10 |
Mdx Management Llc |
Combination of a tyrosine kinase inhibitor and a pro-inflammatory agent for treating cancer
|
WO2024196822A1
(en)
|
2023-03-17 |
2024-09-26 |
Mdx Management Llc |
Compositions and methods for ameliorating adverse effects of therapies
|
WO2024211475A1
(en)
|
2023-04-04 |
2024-10-10 |
Abbott Laboratories |
Use of biomarkers to determine whether a subject has sustained, may have sustained or is suspected of sustaining a subacute acquired brain injury (abi)
|
WO2024226969A1
(en)
|
2023-04-28 |
2024-10-31 |
Abbott Point Of Care Inc. |
Improved assays, cartridges, and kits for detection of biomarkers, including brain injury biomarkers
|