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TNSN97023A1 - Derives de triazole utiles en therapeutique, procedes pour leur preparation et compositions les contenant. - Google Patents

Derives de triazole utiles en therapeutique, procedes pour leur preparation et compositions les contenant.

Info

Publication number
TNSN97023A1
TNSN97023A1 TNTNSN97023A TNSN97023A TNSN97023A1 TN SN97023 A1 TNSN97023 A1 TN SN97023A1 TN TNSN97023 A TNTNSN97023 A TN TNSN97023A TN SN97023 A TNSN97023 A TN SN97023A TN SN97023 A1 TNSN97023 A1 TN SN97023A1
Authority
TN
Tunisia
Prior art keywords
preparation
compositions containing
therapeutics
methods
triazole derivatives
Prior art date
Application number
TNTNSN97023A
Other languages
English (en)
Inventor
Green Stuart
t stephenson Peter
W Murtiashaw Charles
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of TNSN97023A1 publication Critical patent/TNSN97023A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • C07F9/6518—Five-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSES DE FORMULE I : R1 - OP (O) (OH)2 DANS LAQUELLE R1 REPRESENTE LA PORTION NON HYDROXYLIQUE D'UN DERIVE DE TRIAZOLE ANTIFONGIQUE DU TYPE COMPRENANT UN GROUPE HYDROXY TERTIAIRE, OU LEURS SELS PHARMACEUTIQUEMENT ACCEPTABLES. ELLE CONCERNE EGALEMENT DES PROCEDES POUR LEUR PREPARATION ET DES COMPOSITIONS LES CONTENANT. APPLICATION : UTILISATION DES COMPOSES ET COMPOSITIONS DANS LE TRAITEMENT D'INFECTIONS FONGIQUES.
TNTNSN97023A 1996-02-02 1997-01-29 Derives de triazole utiles en therapeutique, procedes pour leur preparation et compositions les contenant. TNSN97023A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9602080.5A GB9602080D0 (en) 1996-02-02 1996-02-02 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
TNSN97023A1 true TNSN97023A1 (fr) 2005-03-15

Family

ID=10787975

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN97023A TNSN97023A1 (fr) 1996-02-02 1997-01-29 Derives de triazole utiles en therapeutique, procedes pour leur preparation et compositions les contenant.

Country Status (43)

Country Link
US (4) US6790957B2 (fr)
EP (1) EP0880533B1 (fr)
JP (1) JP2959846B2 (fr)
KR (1) KR100283546B1 (fr)
CN (1) CN1085213C (fr)
AP (1) AP678A (fr)
AT (1) ATE219089T1 (fr)
AU (1) AU709781B2 (fr)
BG (1) BG63946B1 (fr)
BR (1) BR9707257A (fr)
CA (1) CA2240777C (fr)
CO (1) CO4761066A1 (fr)
CZ (1) CZ291431B6 (fr)
DE (1) DE69713284T2 (fr)
DK (1) DK0880533T3 (fr)
DZ (1) DZ2172A1 (fr)
ES (1) ES2175336T3 (fr)
GB (1) GB9602080D0 (fr)
GT (1) GT199700016A (fr)
HK (1) HK1018217A1 (fr)
HN (1) HN1997000012A (fr)
HR (1) HRP970063B1 (fr)
HU (1) HU226133B1 (fr)
ID (1) ID15858A (fr)
IL (3) IL124865A (fr)
IS (1) IS1995B (fr)
MY (1) MY116849A (fr)
NO (1) NO323771B1 (fr)
NZ (1) NZ330654A (fr)
OA (1) OA10711A (fr)
PL (1) PL187237B1 (fr)
PT (1) PT880533E (fr)
RS (1) RS49526B (fr)
RU (1) RU2176244C2 (fr)
SA (1) SA97170578B1 (fr)
SI (1) SI0880533T1 (fr)
SK (1) SK283136B6 (fr)
TN (1) TNSN97023A1 (fr)
TR (1) TR199801440T2 (fr)
TW (1) TW434247B (fr)
UA (1) UA46828C2 (fr)
WO (1) WO1997028169A1 (fr)
ZA (1) ZA97826B (fr)

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GB9602080D0 (en) * 1996-02-02 1996-04-03 Pfizer Ltd Pharmaceutical compounds
GB9713149D0 (en) 1997-06-21 1997-08-27 Pfizer Ltd Pharmaceutical formulations
DE19751525C2 (de) 1997-11-20 2003-02-13 Bat Cigarettenfab Gmbh Verfahren und Vorrichtung zur Regelung der Ausgangsfeuchte von Tabak
US6265584B1 (en) 1998-05-22 2001-07-24 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
AU1915500A (en) 1998-11-20 2000-06-13 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6235728B1 (en) 1999-02-19 2001-05-22 Bristol-Myers Squibb Company Water-soluble prodrugs of azole compounds
KR20010050557A (ko) * 1999-09-29 2001-06-15 타이도 나오카타 아졸 유도체 또는 그의 염
US6362172B2 (en) * 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6448401B1 (en) * 2000-11-20 2002-09-10 Bristol-Myers Squibb Company Process for water soluble azole compounds
US7540402B2 (en) * 2001-06-29 2009-06-02 Kva, Inc. Method for controlling weld metal microstructure using localized controlled cooling of seam-welded joints
US7323572B2 (en) 2002-07-16 2008-01-29 Pfizer Inc Process for controlling the hydrate mix of a compound
EP1646284A4 (fr) * 2003-07-18 2008-09-24 Rhode Island Education Derives d'azole et procedes de fabrication associes
BRPI0509085A (pt) * 2004-03-24 2007-08-21 Fasgen Llc processo de neuroproteção através da inibição farmacológica da proteìna quinase ativada por amp
CN1303073C (zh) * 2005-05-31 2007-03-07 中国人民解放军第二军医大学 取代三唑酮苄胺三唑醇类抗真菌化合物及其制备方法
WO2007072851A1 (fr) * 2005-12-20 2007-06-28 Eisai R & D Management Co., Ltd. Procede pour produire un promedicament d'azole hydrosoluble
PL1968990T3 (pl) 2005-12-27 2015-06-30 Otsuka Pharma Co Ltd Rozpuszczalny w wodzie związek benzoazepinowy i jego kompozycja farmaceutyczna
ATE482700T1 (de) 2006-02-22 2010-10-15 Eisai R&D Man Co Ltd Stabilisierte pharmazeutische zusammensetzung
WO2009129300A2 (fr) * 2008-04-15 2009-10-22 Schering Corporation Compositions à haute densité contenant du posaconazole et formulations comprenant de telles compositions
CN101575330B (zh) * 2008-05-05 2012-10-31 丽珠医药集团股份有限公司 伏立康唑广谱抗真菌药物化合物、其组合物及用途
WO2011064558A2 (fr) 2009-11-30 2011-06-03 Cipla Limited Composition pharmaceutique
CN103857440B (zh) 2011-06-22 2018-09-25 维奥姆生物科学有限公司 基于缀合物的抗真菌和抗细菌前药
EP2561863A1 (fr) 2011-08-22 2013-02-27 Farmaprojects, S.A.U. Compositions pharmaceutiques comportant du voriconazole
PL2804858T3 (pl) 2012-01-20 2020-06-29 Mycovia Pharmaceuticals, Inc. Związki - inhibitory metaloenzymu
LT2827710T (lt) * 2012-03-19 2020-02-10 Cidara Therapeutics, Inc. Dozavimo režimai, skirti echinokandino klasės junginiams
CN103864844B (zh) * 2012-12-09 2016-10-05 正大天晴药业集团股份有限公司 一种福司氟康唑的制备方法
CN103304600B (zh) * 2013-03-04 2018-05-25 陕西合成药业股份有限公司 一种伏立康唑磷酸酯三水合物及其制备方法和用途
RU2719579C2 (ru) * 2013-03-14 2020-04-21 Сидара Терапьютикс, Инк. Режимы дозирования для соединений класса эхинокандинов
US20140275122A1 (en) 2013-03-14 2014-09-18 Fresenius Kabi Usa, Llc Voriconazole Formulations
KR101814895B1 (ko) 2013-06-04 2018-01-04 바이옴 바이오사이언스 피브이티. 엘티디. 코팅된 입자 및 이를 포함하는 조성물
CN103524560A (zh) * 2013-09-28 2014-01-22 陕西合成药业有限公司 伏立康磷酸酯钠水合物及其多晶型
CN104650140B (zh) * 2013-11-18 2017-11-10 正大天晴药业集团股份有限公司 一种高纯度福司氟康唑的制备方法
CN113559105A (zh) 2014-01-29 2021-10-29 维奥姆治疗有限公司 抗性痤疮的治疗
CN104860992A (zh) * 2014-02-25 2015-08-26 陕西合成药业股份有限公司 一种高纯度福司氟康唑制备方法
CN105985377A (zh) * 2015-02-09 2016-10-05 陕西合成药业股份有限公司 一种福司氟康唑盐水合物及其制备方法
CN106279280A (zh) * 2015-05-25 2017-01-04 西藏卫信康医药股份有限公司 一种化合物及其制备方法和应用
CN106518922A (zh) * 2015-09-12 2017-03-22 陕西合成药业股份有限公司 一种三唑类化合物及其制备方法和用途
CN106546668A (zh) * 2015-09-22 2017-03-29 陕西合成药业股份有限公司 一种分离福司氟康唑或其药用盐有关物质的hplc方法
CN105237569B (zh) * 2015-10-21 2017-07-25 西南科技大学 一种制备2，4‑二氟‑α，α‑二（1氢‑1，2，4‑三唑‑1‑基甲基）苯甲醇磷酸二苄酯的合成方法
CN105753902B (zh) * 2016-04-11 2017-08-25 浙江诚意药业股份有限公司 一种福司氟康唑的制备方法
CN108676031A (zh) * 2018-05-29 2018-10-19 重庆威鹏药业有限公司 水溶性三唑类抗真菌膦酸化合物及其制备方法和应用
CN111171075B (zh) * 2020-04-03 2022-07-12 北京四环生物制药有限公司 一种福司氟康唑的制备方法

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CA2182698A1 (fr) * 1994-02-25 1995-08-31 Jun Sato Emulsions injectables a base de derives fongicides du triazole
GB9512961D0 (en) * 1995-06-26 1995-08-30 Pfizer Ltd Antifungal agents
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Also Published As

Publication number Publication date
US6790957B2 (en) 2004-09-14
OA10711A (en) 2001-06-04
WO1997028169A1 (fr) 1997-08-07
ES2175336T3 (es) 2002-11-16
US20070027115A1 (en) 2007-02-01
DE69713284T2 (de) 2003-03-27
DZ2172A1 (fr) 2002-12-01
GT199700016A (es) 1998-07-24
TR199801440T2 (xx) 1998-10-21
US6977302B2 (en) 2005-12-20
JPH10512599A (ja) 1998-12-02
NZ330654A (en) 1999-08-30
HU226133B1 (en) 2008-05-28
IS4785A (is) 1998-06-26
UA46828C2 (uk) 2002-06-17
DE69713284D1 (de) 2002-07-18
HUP9900949A3 (en) 2001-08-28
ID15858A (id) 1997-08-14
IL124865A0 (en) 1999-01-26
HUP9900949A2 (hu) 2001-05-28
CA2240777C (fr) 2002-06-11
HRP970063A2 (en) 1998-06-30
IS1995B (is) 2005-03-15
KR19990082233A (ko) 1999-11-25
BG63946B1 (bg) 2003-07-31
NO323771B1 (no) 2007-07-02
PL328436A1 (en) 1999-02-01
IL124865A (en) 2002-03-10
PT880533E (pt) 2002-09-30
EP0880533B1 (fr) 2002-06-12
CA2240777A1 (fr) 1997-08-07
DK0880533T3 (da) 2002-07-15
CZ291431B6 (cs) 2003-03-12
CO4761066A1 (es) 1999-04-27
SK283136B6 (sk) 2003-03-04
SA97170578B1 (ar) 2006-01-28
US20030144250A1 (en) 2003-07-31
BG102603A (en) 1999-03-31
BR9707257A (pt) 1999-04-06
AU709781B2 (en) 1999-09-09
NO983560L (no) 1998-08-03
US20040236105A1 (en) 2004-11-25
IL133135A (en) 2003-07-06
AP9700923A0 (en) 1997-01-31
HN1997000012A (es) 1997-06-26
GB9602080D0 (en) 1996-04-03
EP0880533A1 (fr) 1998-12-02
JP2959846B2 (ja) 1999-10-06
MY116849A (en) 2004-04-30
TW434247B (en) 2001-05-16
CZ242098A3 (cs) 1999-05-12
NO983560D0 (no) 1998-08-03
YU2997A (sh) 2000-10-30
HK1018217A1 (en) 1999-12-17
AU1598597A (en) 1997-08-22
KR100283546B1 (ko) 2001-04-02
SK102298A3 (en) 1999-08-06
RS49526B (sr) 2006-12-15
AP678A (en) 1998-09-28
ZA97826B (en) 1998-07-31
RU2176244C2 (ru) 2001-11-27
US20050130940A1 (en) 2005-06-16
CN1210540A (zh) 1999-03-10
SI0880533T1 (en) 2002-08-31
HRP970063B1 (en) 2001-12-31
ATE219089T1 (de) 2002-06-15
PL187237B1 (pl) 2004-06-30
CN1085213C (zh) 2002-05-22
IL133135A0 (en) 2001-03-19

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