US6582959B2
(en)
|
1991-03-29 |
2003-06-24 |
Genentech, Inc. |
Antibodies to vascular endothelial cell growth factor
|
US6238884B1
(en)
|
1995-12-07 |
2001-05-29 |
Diversa Corporation |
End selection in directed evolution
|
US6562594B1
(en)
|
1999-09-29 |
2003-05-13 |
Diversa Corporation |
Saturation mutagenesis in directed evolution
|
US6537776B1
(en)
|
1999-06-14 |
2003-03-25 |
Diversa Corporation |
Synthetic ligation reassembly in directed evolution
|
US6939689B2
(en)
|
1995-12-07 |
2005-09-06 |
Diversa Corporation |
Exonuclease-mediated nucleic acid reassembly in directed evolution
|
US6352842B1
(en)
|
1995-12-07 |
2002-03-05 |
Diversa Corporation |
Exonucease-mediated gene assembly in directed evolution
|
US6171820B1
(en)
|
1995-12-07 |
2001-01-09 |
Diversa Corporation |
Saturation mutagenesis in directed evolution
|
US6740506B2
(en)
|
1995-12-07 |
2004-05-25 |
Diversa Corporation |
End selection in directed evolution
|
US7018793B1
(en)
|
1995-12-07 |
2006-03-28 |
Diversa Corporation |
Combinatorial screening of mixed populations of organisms
|
US6358709B1
(en)
|
1995-12-07 |
2002-03-19 |
Diversa Corporation |
End selection in directed evolution
|
US6361974B1
(en)
|
1995-12-07 |
2002-03-26 |
Diversa Corporation |
Exonuclease-mediated nucleic acid reassembly in directed evolution
|
US5830696A
(en)
|
1996-12-05 |
1998-11-03 |
Diversa Corporation |
Directed evolution of thermophilic enzymes
|
US6713279B1
(en)
|
1995-12-07 |
2004-03-30 |
Diversa Corporation |
Non-stochastic generation of genetic vaccines and enzymes
|
US7122636B1
(en)
|
1997-02-21 |
2006-10-17 |
Genentech, Inc. |
Antibody fragment-polymer conjugates and uses of same
|
JP3521382B2
(ja)
|
1997-02-27 |
2004-04-19 |
日本たばこ産業株式会社 |
細胞間接着及びシグナル伝達を媒介する細胞表面分子
|
US7112655B1
(en)
|
1997-02-27 |
2006-09-26 |
Japan Tobacco, Inc. |
JTT-1 protein and methods of inhibiting lymphocyte activation
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
DK0973804T3
(da)
|
1997-04-07 |
2007-05-07 |
Genentech Inc |
Anti-VEGF-antistoffer
|
US7365166B2
(en)
|
1997-04-07 |
2008-04-29 |
Genentech, Inc. |
Anti-VEGF antibodies
|
US20020032315A1
(en)
|
1997-08-06 |
2002-03-14 |
Manuel Baca |
Anti-vegf antibodies
|
US6864227B1
(en)
|
1998-04-13 |
2005-03-08 |
California Institute Of Technology |
Artery-and vein-specific proteins and uses therefor
|
US6887674B1
(en)
|
1998-04-13 |
2005-05-03 |
California Institute Of Technology |
Artery- and vein-specific proteins and uses therefor
|
AU1728800A
(en)
|
1998-11-18 |
2000-06-05 |
Genentech Inc. |
Antibody variants with higher binding affinity compared to parent antibodies
|
SI1135498T1
(sl)
|
1998-11-18 |
2008-06-30 |
Genentech Inc |
Variante protitelesa z višjo vezavno afiniteto vprimerjavi z izvirnimi protitelesi
|
WO2000034337A1
(en)
*
|
1998-12-10 |
2000-06-15 |
Tsukuba Research Laboratory, Toagosei Co., Ltd. |
Humanized monoclonal antibodies against vascular endothelial cell growth factor
|
EP1140173B2
(de)
*
|
1998-12-22 |
2013-04-03 |
Genentech, Inc. |
Antagonisten von vaskular-endothelialen zellwachstumsfaktoren und ihre anwendung
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
WO2004009618A2
(en)
|
2002-07-18 |
2004-01-29 |
Crucell Holland B.V. |
Recombinant production of mixtures of antibodies
|
US6703020B1
(en)
|
1999-04-28 |
2004-03-09 |
Board Of Regents, The University Of Texas System |
Antibody conjugate methods for selectively inhibiting VEGF
|
IL145941A
(en)
|
1999-04-28 |
2007-08-19 |
Univ Texas |
Preparations and methods for the treatment of cancer by selective inhibition of VEGF
|
TWI290146B
(en)
*
|
1999-07-29 |
2007-11-21 |
Dyax Corp |
Binding moieties for fibrin
|
JP3871503B2
(ja)
|
1999-08-30 |
2007-01-24 |
日本たばこ産業株式会社 |
免疫性疾患治療剤
|
JP4210454B2
(ja)
|
2001-03-27 |
2009-01-21 |
日本たばこ産業株式会社 |
炎症性腸疾患治療剤
|
EP1757311B1
(de)
|
1999-12-24 |
2009-02-11 |
Genentech, Inc. |
Verfahren und Zusammensetzungen zur Verlängerung der Entsorgungshalbwertszeit von biowirksamen Verbindungen
|
DE60030323T2
(de)
|
1999-12-24 |
2007-10-11 |
Genentech, Inc., South San Francisco |
Verfahren und verbindungen zur verlängerung der halbwertzeiten bei der ausscheidung von biowirksamen verbindungen
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
JP3597140B2
(ja)
|
2000-05-18 |
2004-12-02 |
日本たばこ産業株式会社 |
副刺激伝達分子ailimに対するヒトモノクローナル抗体及びその医薬用途
|
EP2042597B1
(de)
|
2000-06-23 |
2014-05-07 |
Genentech, Inc. |
Zusammensetzungen und Verfahren zur Diagnose und Behandlung von Erkrankungen in Verbindung mit Angiogenese
|
EP2075253A1
(de)
|
2000-06-23 |
2009-07-01 |
Genentech, Inc. |
Methoden und Verbindungen zur Diagnose und Behandlung von Krankheiten, an denen Angiogenese beteiligt ist
|
US6902718B2
(en)
|
2000-10-24 |
2005-06-07 |
Diatide, Inc. |
Stabilization of radiopharmaceutical compositions using hydrophilic thioethers
|
US6989138B2
(en)
|
2000-10-24 |
2006-01-24 |
Diatide, Inc. |
Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans
|
JP4212278B2
(ja)
|
2001-03-01 |
2009-01-21 |
日本たばこ産業株式会社 |
移植片拒絶反応抑制剤
|
US7117096B2
(en)
|
2001-04-17 |
2006-10-03 |
Abmaxis, Inc. |
Structure-based selection and affinity maturation of antibody library
|
US7667004B2
(en)
|
2001-04-17 |
2010-02-23 |
Abmaxis, Inc. |
Humanized antibodies against vascular endothelial growth factor
|
TWI284539B
(en)
|
2001-07-30 |
2007-08-01 |
Epix Pharm Inc |
A method for making a magnetic resonance (MR) imaging agent, a MR imaging contrast agent, a method for altering stability of a peptide and a modified peptide
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
EP1443961B1
(de)
*
|
2001-10-25 |
2009-05-06 |
Genentech, Inc. |
Glycoprotein-zusammensetzungen
|
US20030190705A1
(en)
*
|
2001-10-29 |
2003-10-09 |
Sunol Molecular Corporation |
Method of humanizing immune system molecules
|
ATE417858T1
(de)
|
2002-02-05 |
2009-01-15 |
Genentech Inc |
Proteinaufreinigung
|
WO2003102132A2
(en)
|
2002-04-26 |
2003-12-11 |
Genetech, Inc. |
Non-affinity purification of proteins
|
EP2316921B1
(de)
*
|
2002-05-24 |
2014-05-14 |
Merck Sharp & Dohme Corp. |
Humaner neutraliserender Anti-IGFR Antikörper
|
US7696320B2
(en)
|
2004-08-24 |
2010-04-13 |
Domantis Limited |
Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
|
WO2007066106A1
(en)
*
|
2005-12-06 |
2007-06-14 |
Domantis Limited |
Ligands that have binding specificity for egfr and/or vegf and methods of use therefor
|
US9028822B2
(en)
|
2002-06-28 |
2015-05-12 |
Domantis Limited |
Antagonists against TNFR1 and methods of use therefor
|
AU2003247869C1
(en)
|
2002-07-15 |
2009-12-24 |
Board Of Regents, The University Of Texas System |
Selected antibodies binding to anionic phospholipids and aminophospholipids and their use in treating viral infections and cancer
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
US7491509B2
(en)
|
2003-02-03 |
2009-02-17 |
Fraunhofer Usa, Inc. |
System for expression of genes in plants
|
US7575893B2
(en)
|
2003-01-23 |
2009-08-18 |
Genentech, Inc. |
Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture
|
US7381410B2
(en)
|
2003-03-12 |
2008-06-03 |
Vasgene Therapeutics, Inc. |
Polypeptide compounds for inhibiting angiogenesis and tumor growth
|
WO2004080425A2
(en)
|
2003-03-12 |
2004-09-23 |
Vasgene Therapeutics, Inc. |
Polypeptide compounds for inhibiting angiogenesis and tumor growth
|
WO2008109433A2
(en)
|
2007-03-02 |
2008-09-12 |
The Cleveland Clinic Foundation |
Anti-angiogenic peptides
|
ES2427641T3
(es)
|
2003-05-22 |
2013-10-31 |
Ibio, Inc. |
Molécula vehículo recombinante para la expresión, el suministro y la purificación de polipéptidos diana
|
CN1829741A
(zh)
|
2003-05-30 |
2006-09-06 |
健泰科生物技术公司 |
利用抗-vegf抗体的治疗
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
ES2786568T3
(es)
|
2003-07-28 |
2020-10-13 |
Genentech Inc |
Reducción de la lixiviación de la proteína A durante la cromatografía de afinidad con proteína A
|
JP2007501011A
(ja)
*
|
2003-08-01 |
2007-01-25 |
ジェネンテック・インコーポレーテッド |
制限多様性配列を有する結合型ポリペプチド
|
US20050106667A1
(en)
|
2003-08-01 |
2005-05-19 |
Genentech, Inc |
Binding polypeptides with restricted diversity sequences
|
US7758859B2
(en)
|
2003-08-01 |
2010-07-20 |
Genentech, Inc. |
Anti-VEGF antibodies
|
US7920906B2
(en)
|
2005-03-10 |
2011-04-05 |
Dexcom, Inc. |
System and methods for processing analyte sensor data for sensor calibration
|
NZ546088A
(en)
*
|
2003-08-27 |
2009-10-30 |
Ophthotech Corp |
Combination therapy for the treatment of ocular neovascular disorders using a PDGF antagonist and a VEGF antagonist
|
FR2859725B1
(fr)
*
|
2003-09-16 |
2006-03-10 |
Neovacs |
Procede a haut rendement pour l'obtention d'anticorps humains neutralisant l'activite biologique d'une cytokine humaine
|
US9247900B2
(en)
|
2004-07-13 |
2016-02-02 |
Dexcom, Inc. |
Analyte sensor
|
JP5912211B2
(ja)
|
2004-01-20 |
2016-04-27 |
メルス ビー.ヴィー. |
結合タンパク質の混合物
|
ES2337473T3
(es)
|
2004-02-19 |
2010-04-26 |
Genentech, Inc. |
Anticuerpos reparadores con cdr.
|
CN102718867A
(zh)
|
2004-03-12 |
2012-10-10 |
瓦斯基因治疗公司 |
结合ephb4、抑制血管发生和肿瘤生长的抗体
|
WO2005090406A2
(en)
|
2004-03-12 |
2005-09-29 |
Vasgene Therapeutics, Inc. |
Antibodies binding to ephb4 for inhibiting angiogenesis and tumor growth
|
US8921528B2
(en)
|
2004-06-01 |
2014-12-30 |
Domantis Limited |
Bispecific fusion antibodies with enhanced serum half-life
|
WO2006127694A2
(en)
|
2004-07-13 |
2006-11-30 |
Dexcom, Inc. |
Analyte sensor
|
US7654956B2
(en)
|
2004-07-13 |
2010-02-02 |
Dexcom, Inc. |
Transcutaneous analyte sensor
|
RU2392966C2
(ru)
*
|
2004-07-20 |
2010-06-27 |
Дженентек, Инк. |
Ингибиторы ангиопоэтинподобного белка 4, их комбинации и применение
|
US8604185B2
(en)
|
2004-07-20 |
2013-12-10 |
Genentech, Inc. |
Inhibitors of angiopoietin-like 4 protein, combinations, and their use
|
EP1771476B1
(de)
|
2004-07-23 |
2014-12-10 |
Genentech, Inc. |
Kristallisierung von anti-vegf antikörpern
|
US7662926B2
(en)
|
2004-09-02 |
2010-02-16 |
Genentech, Inc. |
Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor
|
US7655229B2
(en)
|
2004-09-02 |
2010-02-02 |
Chan Andrew C |
Anti-FC-gamma RIIB receptor antibody and uses therefor
|
ES2529451T3
(es)
|
2004-09-23 |
2015-02-20 |
Vasgene Therapeutics, Inc. |
Compuestos polipeptídicos para inhibir la angiogénesis y el crecimiento tumoral
|
CA2584305A1
(en)
|
2004-10-21 |
2006-05-04 |
Genentech, Inc. |
Method for treating intraocular neovascular diseases
|
NZ556635A
(en)
|
2004-12-22 |
2010-11-26 |
Genentech Inc |
Method for producing soluble multi-membrane-spanning proteins
|
US8236283B2
(en)
*
|
2005-01-06 |
2012-08-07 |
Ge Healthcare As |
Optical imaging
|
US8735394B2
(en)
|
2005-02-18 |
2014-05-27 |
Abraxis Bioscience, Llc |
Combinations and modes of administration of therapeutic agents and combination therapy
|
US20070166388A1
(en)
|
2005-02-18 |
2007-07-19 |
Desai Neil P |
Combinations and modes of administration of therapeutic agents and combination therapy
|
DK2301531T3
(en)
|
2005-02-18 |
2018-07-30 |
Abraxis Bioscience Llc |
COMBINATIONS AND WAYS FOR ADMINISTRATING THERAPEUTIC SUBSTANCES AND COMBINATION THERAPY
|
US20160355591A1
(en)
|
2011-05-02 |
2016-12-08 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
DK2586459T3
(en)
|
2005-03-25 |
2017-09-11 |
Regeneron Pharma |
VEGF antagonist formulations
|
CN101222926B
(zh)
*
|
2005-04-15 |
2013-07-17 |
默沙东公司 |
用于治疗或预防癌症的方法和组合物
|
CA2606084A1
(en)
*
|
2005-06-17 |
2006-12-28 |
Abbott Laboratories |
Improved method of treating degenerative spinal disorders
|
JP5196654B2
(ja)
*
|
2005-06-20 |
2013-05-15 |
ジェネンテック, インコーポレイテッド |
腫瘍の診断と治療のための組成物と方法
|
USRE47223E1
(en)
|
2005-06-20 |
2019-02-05 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
WO2007117264A2
(en)
|
2005-08-03 |
2007-10-18 |
Fraunhofer Usa, Inc. |
Compositions and methods for production of immunoglobulins
|
EP2399573B1
(de)
|
2005-08-31 |
2019-01-02 |
Abraxis BioScience, LLC |
Zusammensetzungen aus schwer wasserlöslichen pharmazeutischen Mitteln
|
UA96139C2
(uk)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)
|
KR100877824B1
(ko)
|
2005-11-11 |
2009-01-12 |
한국생명공학연구원 |
E2epf ucp-vhl 상호작용 및 그 용도
|
EP1959958A4
(de)
*
|
2005-11-14 |
2010-07-14 |
Univ Southern California |
Integrin-bindende kleine moleküle
|
ES2400666T5
(es)
†
|
2005-12-16 |
2016-03-10 |
Regeneron Pharmaceuticals, Inc. |
Uso terapéutico de un antagonista de DII4 y un inhibidor de VEGF para inhibir el crecimiento tumoral
|
PT1973950E
(pt)
|
2006-01-05 |
2014-12-29 |
Genentech Inc |
Anticorpos anti-epbh4 e métodos que os utilizam
|
CA2638133A1
(en)
|
2006-01-20 |
2007-11-08 |
Genentech, Inc. |
Anti-ephrinb2 antibodies and methods using same
|
KR20080106433A
(ko)
|
2006-02-13 |
2008-12-05 |
프라운호퍼 유에스에이, 인코포레이티드 |
인플루엔자 항원, 백신 조성물 및 관련 방법
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
WO2008060645A2
(en)
|
2006-03-21 |
2008-05-22 |
Genentech, Inc. |
Combinatorial therapy involving alpha5beta1 antagonists
|
TW200812615A
(en)
*
|
2006-03-22 |
2008-03-16 |
Hoffmann La Roche |
Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2
|
UA95797C2
(ru)
*
|
2006-03-22 |
2011-09-12 |
Ф. Хоффманн-Ля Рош Аг |
Терапия опухолей с использованием сосудистого эндотелиального фактора роста и антитела к рецептору типа 2 человеческого эпителиального фактора роста
|
ZA200807590B
(en)
*
|
2006-03-29 |
2009-11-25 |
Genentech Inc |
Diagnostics and treatments for tumors
|
AU2007237096C1
(en)
|
2006-04-07 |
2012-12-13 |
EyePoint Pharmaceuticals, Inc. |
Antibodies that bind human protein tyrosine phosphatase beta (HPTPbeta) and uses thereof
|
WO2007143689A2
(en)
*
|
2006-06-06 |
2007-12-13 |
Genentech, Inc. |
Compositions and methods for modulating vascular development
|
NZ572177A
(en)
|
2006-06-06 |
2012-02-24 |
Genentech Inc |
Anti-dll4 antibodies and methods using same
|
CA2654510C
(en)
|
2006-06-16 |
2015-03-17 |
Regeneron Pharmaceuticals, Inc. |
Vegf antagonist formulations suitable for intravitreal administration
|
FR2902799B1
(fr)
|
2006-06-27 |
2012-10-26 |
Millipore Corp |
Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
|
WO2008011513A2
(en)
|
2006-07-19 |
2008-01-24 |
The Cleveland Clinic Foundation |
Compounds and methods of modulating angiogenesis
|
CN100448892C
(zh)
*
|
2006-08-02 |
2009-01-07 |
中国人民解放军军事医学科学院基础医学研究所 |
抗肿瘤血管内皮生长因子受体vegf-r2抗原及其编码基因与应用
|
MX2009001715A
(es)
|
2006-08-21 |
2009-02-25 |
Hoffmann La Roche |
Terapia tumoral con un anticuerpo anti-vegf.
|
DK2066694T3
(en)
|
2006-09-29 |
2016-02-08 |
Oncomed Pharm Inc |
Compositions and Methods for Diagnosing and Treating Cancer
|
BRPI0715239A2
(pt)
|
2006-10-04 |
2013-06-25 |
Genentech Inc |
mÉtodo para detectar formas de fator de crescimento endotelial vascular (vegf) seletivas (vegf110+), kit de imunoensaio, anticorpo 5c3 e hibridoma 5c3.1.1
|
CN102006885A
(zh)
*
|
2006-10-20 |
2011-04-06 |
先灵公司 |
完全人源抗vegf抗体及其使用方法
|
MX2009006779A
(es)
*
|
2006-12-19 |
2009-08-27 |
Genentech Inc |
Antagonistas especificos para terapia con adyuvantes y neo-adyuvantes y el tratamiento de tumores en etapa temprana.
|
WO2008079280A1
(en)
|
2006-12-21 |
2008-07-03 |
Millipore Corporation |
Purification of proteins
|
US8569464B2
(en)
|
2006-12-21 |
2013-10-29 |
Emd Millipore Corporation |
Purification of proteins
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
AU2008209404B2
(en)
|
2007-01-22 |
2012-08-16 |
Genentech, Inc. |
Polyelectrolyte precipitation and purification of antibodies
|
US20100119526A1
(en)
*
|
2007-01-26 |
2010-05-13 |
Bioinvent International Ab |
DLL4 Signaling Inhibitors and Uses Thereof
|
RU2009133784A
(ru)
|
2007-02-09 |
2011-03-20 |
Дженентек, Инк. (Us) |
АНТИ-Robo4-АНТИТЕЛА И ИХ ПРИМЕНЕНИЯ
|
CL2008001334A1
(es)
|
2007-05-08 |
2008-09-22 |
Genentech Inc |
Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer.
|
ES2469743T3
(es)
|
2007-05-17 |
2014-06-18 |
Genentech, Inc. |
Inhibición de la metástasis tumoral por anticuerpos anti neuropilina 2
|
PE20090321A1
(es)
|
2007-06-04 |
2009-04-20 |
Genentech Inc |
Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
|
DE17196350T1
(de)
|
2007-07-09 |
2018-12-27 |
Genentech, Inc. |
Verhindern der disulfid-bindungsreduktion während der rekombinanten herstellung von polypeptiden
|
WO2009009759A2
(en)
|
2007-07-11 |
2009-01-15 |
Fraunhofer Usa, Inc. |
Yersinia pestis antigens, vaccine compositions, and related methods
|
JP5749009B2
(ja)
|
2007-08-13 |
2015-07-15 |
バスジーン セラピューティクス, インコーポレイテッドVasgenetherapeutics, Inc. |
EphB4に結合するヒト化抗体を利用する癌治療剤
|
JP6035009B2
(ja)
|
2007-08-22 |
2016-11-30 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
活性化可能な結合ポリペプチドおよびその同定方法ならびに使用
|
RU2498991C2
(ru)
*
|
2007-10-30 |
2013-11-20 |
Дженентек, Инк. |
Очистка антител с помощью катионообменной хроматографии
|
MX2010005104A
(es)
|
2007-11-09 |
2010-08-04 |
Peregrine Pharmaceuticals Inc |
Composiciones de anticuerpo anti-factor de crecimiento endotelial vascular y metodos.
|
PE20090983A1
(es)
|
2007-11-09 |
2009-08-13 |
Genentech Inc |
Composiciones y metodos de uso de la quinasa-1 similar al receptor de la activina
|
AR069501A1
(es)
|
2007-11-30 |
2010-01-27 |
Genentech Inc |
Anticuerpos anti- vegf (factor de crecimiento endotelial vascular)
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
SI2644204T1
(sl)
|
2008-03-18 |
2017-08-31 |
Genentech, Inc. |
Kombinacije konjugata protitelo proti HER2-zdravilo in pertuzumaba
|
EP2274008B1
(de)
*
|
2008-03-27 |
2014-02-26 |
ZymoGenetics, Inc. |
Zusammensetzungen und verfahren zur hemmung von pdgfrbeta und vegf-a
|
EP2280997A2
(de)
*
|
2008-04-18 |
2011-02-09 |
Xencor, Inc. |
Aus nichthumanen variablen regionen gentechnisch hergestellte humanäquivalente monoklonale antikörper
|
NZ588554A
(en)
|
2008-04-29 |
2013-03-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
TW201008580A
(en)
|
2008-06-03 |
2010-03-01 |
Abbott Lab |
Dual variable domain immunoglobulin and uses thereof
|
AR072000A1
(es)
|
2008-06-03 |
2010-07-28 |
Abbott Lab |
Proteinas de union multivalentes con capacidad de unir dos o mas antigenos y usos de la misma
|
US8999702B2
(en)
|
2008-06-11 |
2015-04-07 |
Emd Millipore Corporation |
Stirred tank bioreactor
|
BRPI0914251B1
(pt)
|
2008-06-25 |
2022-07-19 |
Novartis Ag |
Imunoligante recombinante, seu fragmento de ligação ao antígeno, uso dos mesmos, e composição
|
CA2729949A1
(en)
*
|
2008-07-08 |
2010-01-14 |
Abbott Laboratories |
Prostaglandin e2 dual variable domain immunoglobulins and uses thereof
|
US20100029491A1
(en)
*
|
2008-07-11 |
2010-02-04 |
Maike Schmidt |
Methods and compositions for diagnostic use for tumor treatment
|
JP5606438B2
(ja)
|
2008-07-23 |
2014-10-15 |
エフ.ホフマン−ラ ロシュ アーゲー |
抗血管新生療法を受容可能な被験体の同定
|
KR101843915B1
(ko)
|
2008-08-14 |
2018-04-02 |
제넨테크, 인크. |
고유 단백질 대체 이온 교환 막 크로마토그래피를 이용한 오염물의 제거 방법
|
AR073231A1
(es)
*
|
2008-08-29 |
2010-10-20 |
Genentech Inc |
Metodos diagnosticos y tratamientos para los tumores independientes del vegf (factor de crecimiento endotelial vascular)
|
EP2331133A4
(de)
|
2008-09-05 |
2012-09-12 |
Univ Duke |
Anti-lipid-antikörper
|
EP2334323A2
(de)
|
2008-09-10 |
2011-06-22 |
F. Hoffmann-La Roche AG |
Zusammensetzungen und verfahren zur prävention des oxidativen abbaus von proteinen
|
WO2010037046A1
(en)
|
2008-09-28 |
2010-04-01 |
Fraunhofer Usa, Inc. |
Humanized neuraminidase antibody and methods of use thereof
|
US8268314B2
(en)
|
2008-10-08 |
2012-09-18 |
Hoffmann-La Roche Inc. |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
PE20110707A1
(es)
|
2008-10-14 |
2011-10-11 |
Genentech Inc |
Variantes de inmunoglobulinas
|
MX359570B
(es)
|
2008-11-03 |
2018-10-01 |
Molecular Partners Ag |
Proteinas de union que inhiben la interaccion en el receptor de vegf-a.
|
KR101719376B1
(ko)
|
2008-11-05 |
2017-03-23 |
제넨테크, 인크. |
연령-관련 황반 변성에서 유전자 다형성
|
HUE024872T2
(en)
|
2008-11-22 |
2016-02-29 |
Hoffmann La Roche |
Use of anti-vegf antibody in combination with chemotherapy for treating breast cancer
|
US20110020327A1
(en)
|
2008-12-16 |
2011-01-27 |
Millipore Corporation |
Purification of proteins
|
WO2010074953A1
(en)
|
2008-12-16 |
2010-07-01 |
Millipore Corporation |
Stirred tank reactor and method
|
CA2746120A1
(en)
|
2008-12-23 |
2010-07-01 |
Genentech, Inc. |
Methods and compositions for diagnostic use in cancer patients
|
CN102482347B
(zh)
|
2009-01-12 |
2017-04-26 |
希托马克斯医疗有限责任公司 |
修饰抗体组合物及其制备和使用方法
|
WO2010081838A2
(en)
|
2009-01-14 |
2010-07-22 |
Novartis Ag |
Sterile prefilled container
|
JP2012517434A
(ja)
|
2009-02-06 |
2012-08-02 |
ザ ジェネラル ホスピタル コーポレイション |
血管病変を治療する方法
|
AU2010215761B2
(en)
*
|
2009-02-23 |
2017-04-06 |
Cytomx Therapeutics, Inc |
Proproteins and methods of use thereof
|
US8435488B2
(en)
|
2009-02-27 |
2013-05-07 |
Genentech, Inc. |
Methods and compositions for protein labelling
|
AU2010224012B2
(en)
|
2009-03-13 |
2016-04-28 |
Abraxis Bioscience, Llc |
Combination therapy with thiocolchicine derivatives
|
AR075925A1
(es)
|
2009-03-25 |
2011-05-04 |
Genentech Inc |
Anticuerpos anti-alfa5beta1 (alfa5beta1: glicoproteina integrina) y sus usos
|
MX2011010159A
(es)
|
2009-04-02 |
2011-10-17 |
Roche Glycart Ag |
Anticuerpos multiespecificos que comprenden anticuerpos de longitud completa y fragmentos fab de cadena sencilla.
|
KR101456326B1
(ko)
|
2009-04-07 |
2014-11-12 |
로슈 글리카트 아게 |
3가, 이중특이적 항체
|
BRPI1012524A2
(pt)
*
|
2009-04-16 |
2020-09-29 |
Abbott Biotherapeutics Corp |
anticorpos anti-tnf-alfa e seus usos
|
JP2012524083A
(ja)
*
|
2009-04-20 |
2012-10-11 |
ジェネンテック, インコーポレイテッド |
アジュバント癌治療
|
US9067986B2
(en)
|
2009-04-27 |
2015-06-30 |
Oncomed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
EP2427479B1
(de)
|
2009-05-07 |
2018-11-21 |
The Regents of The University of California |
Antikörper und verfahren zu ihrer verwendung
|
CA2665956A1
(en)
*
|
2009-05-07 |
2010-11-07 |
Samir Patel |
Combination treatment for ocular diseases
|
US8404811B2
(en)
|
2009-05-08 |
2013-03-26 |
Genentech, Inc. |
Humanized anti-EGFL7 antibodies and methods using same
|
WO2010129917A2
(en)
|
2009-05-08 |
2010-11-11 |
Vaccinex, Inc. |
Anti-cd100 antibodies and methods for using the same
|
JP5925677B2
(ja)
|
2009-06-15 |
2016-06-01 |
アイコン・ジェネティクス・ゲーエムベーハー |
キシロシルトランスフェラーゼ活性の欠損したベンサミアナタバコ(Nicotianabenthamiana)植物
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
AU2010273585B2
(en)
|
2009-07-13 |
2015-04-23 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
AR078060A1
(es)
|
2009-07-14 |
2011-10-12 |
Novartis Ag |
Descontaminacion de superficie de contenedores previamente llenados en empaque secundario
|
WO2011014457A1
(en)
|
2009-07-27 |
2011-02-03 |
Genentech, Inc. |
Combination treatments
|
MX2012001306A
(es)
|
2009-07-31 |
2012-02-28 |
Genentech Inc |
Inhibicion de matastasis de tumor.
|
ES2793348T3
(es)
|
2009-08-11 |
2020-11-13 |
Hoffmann La Roche |
Producción de proteínas en medios de cultivo celular libres de glutamina
|
EP2464744A1
(de)
|
2009-08-14 |
2012-06-20 |
F. Hoffmann-La Roche AG |
Biologische marker zur überwachung der patientenreaktion auf vegf-antagonisten
|
WO2011022264A1
(en)
|
2009-08-15 |
2011-02-24 |
Genentech, Inc. |
Anti-angiogenesis therapy for the treatment of previously treated breast cancer
|
US9428548B2
(en)
|
2009-09-01 |
2016-08-30 |
Genentech, Inc. |
Enhanced protein purification through a modified protein A elution
|
US8642515B2
(en)
|
2009-09-04 |
2014-02-04 |
University Of Louisville Research Foundation, Inc. |
Genetic determinants of prostate cancer risk
|
JP2013504595A
(ja)
|
2009-09-11 |
2013-02-07 |
ジェネンテック, インコーポレイテッド |
抗癌剤に対する応答の可能性が増加した患者を同定するための方法
|
RU2015153109A
(ru)
|
2009-09-16 |
2019-01-15 |
Дженентек, Инк. |
Содержащие суперспираль и/или привязку белковые комплексы и их применения
|
US20110064732A1
(en)
|
2009-09-17 |
2011-03-17 |
Sanne Lysbet De Haas |
Methods and compositions for diagnostic use in cancer patients
|
WO2011041391A1
(en)
|
2009-09-29 |
2011-04-07 |
Fraunhofer Usa, Inc. |
Influenza hemagglutinin antibodies, compositions, and related methods
|
ES2895226T3
(es)
|
2009-10-16 |
2022-02-18 |
Mereo Biopharma 5 Inc |
Combinación terapéutica y uso de anticuerpos antagonistas de DLL4 y agentes antihipertensivos
|
DK2491134T3
(en)
|
2009-10-21 |
2017-09-18 |
Genentech Inc |
Genetic polymorphisms in age-related macular degeneration
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
ES2565208T3
(es)
|
2009-12-11 |
2016-04-01 |
F. Hoffmann-La Roche Ag |
Anticuerpos anti-VEGF-C y métodos de uso de los mismos
|
US8765432B2
(en)
|
2009-12-18 |
2014-07-01 |
Oligasis, Llc |
Targeted drug phosphorylcholine polymer conjugates
|
MX2012006831A
(es)
|
2009-12-21 |
2012-08-17 |
Genentech Inc |
Formacion de anticuerpos.
|
NZ600826A
(en)
|
2009-12-23 |
2014-09-26 |
Genentech Inc |
Anti-bv8 antibodies and uses thereof
|
EP2519536A4
(de)
|
2009-12-29 |
2013-06-05 |
Reddys Lab Ltd Dr |
Proteinreinigung durch ionenaustausch
|
WO2011095596A1
(en)
|
2010-02-04 |
2011-08-11 |
Vivalis |
Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells
|
CN110227154A
(zh)
|
2010-02-23 |
2019-09-13 |
霍夫曼-拉罗奇有限公司 |
用于治疗卵巢癌的抗血管发生疗法
|
CN104998269B
(zh)
|
2010-03-22 |
2019-06-11 |
弗·哈夫曼-拉罗切有限公司 |
对于稳定含有蛋白质的制剂有用的组合物和方法
|
TWI426920B
(zh)
|
2010-03-26 |
2014-02-21 |
Hoffmann La Roche |
雙專一性、雙價抗-vegf/抗-ang-2抗體
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
EP2552439B1
(de)
|
2010-03-29 |
2022-07-20 |
Abraxis BioScience, LLC |
Verfahren zur verstärkung einer wirkstofffreisetzung und der wirksamkeit von therapiemitteln
|
DK2552415T3
(en)
|
2010-03-29 |
2016-11-28 |
Abraxis Bioscience Llc |
Methods for treating cancer
|
WO2011133521A2
(en)
|
2010-04-19 |
2011-10-27 |
Synta Pharmaceuticals Corp. |
Cancer therapy using a combination of a hsp90 inhibitory compounds and a vegf inhibitor
|
TWI510246B
(zh)
|
2010-04-30 |
2015-12-01 |
Molecular Partners Ag |
抑制vegf-a受體交互作用的經修飾結合性蛋白質
|
KR20130060227A
(ko)
|
2010-05-03 |
2013-06-07 |
제넨테크, 인크. |
단백질-함유 제제의 점도 감소에 유용한 조성물 및 방법
|
SG10201804385YA
(en)
|
2010-05-17 |
2018-06-28 |
Emd Millipore Corp |
Stimulus responsive polymers for the purification of biomolecules
|
PL2576580T3
(pl)
|
2010-05-28 |
2017-03-31 |
F.Hoffmann-La Roche Ag |
Zmniejszenie poziomu mleczanu i zwiększenie wytwarzania polipeptydu przez obniżenie poziomu ekspresji dehydrogenazy mleczanowej i kinazy dehydrogenazy pirogronianowej
|
WO2011153224A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
WO2011153243A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Anti-angiogenesis therapy for treating gastric cancer
|
KR20130088116A
(ko)
|
2010-06-04 |
2013-08-07 |
아브락시스 바이오사이언스, 엘엘씨 |
췌장암의 치료 방법
|
SI2585045T1
(sl)
|
2010-06-24 |
2019-11-29 |
Hoffmann La Roche |
Sestavki in postopki, ki vsebujejo alkilglikozide za stabilizacijo formulacij, ki vsebujejo beljakovine
|
KR20130100973A
(ko)
|
2010-07-02 |
2013-09-12 |
제넨테크, 인크. |
항-vegf 요법을 사용하는 혈관화 색소 상피 박리의 치료
|
KR20130120439A
(ko)
|
2010-07-09 |
2013-11-04 |
제넨테크, 인크. |
항-뉴로필린 항체 및 사용 방법
|
BR112013001433A2
(pt)
|
2010-07-19 |
2016-05-31 |
Hoffmann La Roche |
método de identificação de pacientes com maior probabilidade de responder a terapia anticâncer
|
BR112012033162A2
(pt)
|
2010-07-19 |
2016-10-25 |
Hoffmann La Roche |
método de identificação de pacientes, método de previsão da capacidade de reação de pacientes, método de determinação da probabilidade de um paciente com câncer exibir benefícios de terapia anticâncer, método de otimização da eficácia terapêutica, método de tratamento de câncer, kit e conjunto de compostos
|
AU2011285852B2
(en)
|
2010-08-03 |
2014-12-11 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
JP2013537539A
(ja)
|
2010-08-13 |
2013-10-03 |
ジェネンテック, インコーポレイテッド |
疾患の治療のためのIL−1β及びIL−18に対する抗体
|
TW201208703A
(en)
|
2010-08-17 |
2012-03-01 |
Roche Glycart Ag |
Combination therapy of an afucosylated CD20 antibody with an anti-VEGF antibody
|
KR101586128B1
(ko)
|
2010-08-24 |
2016-01-15 |
에프. 호프만-라 로슈 아게 |
디술피드 안정화 ― Fv 단편을 포함하는 이중특이적 항체
|
SG187938A1
(en)
|
2010-08-26 |
2013-04-30 |
Abbvie Inc |
Dual variable domain immunoglobulins and uses thereof
|
WO2012030512A1
(en)
|
2010-09-03 |
2012-03-08 |
Percivia Llc. |
Flow-through protein purification process
|
US8551479B2
(en)
|
2010-09-10 |
2013-10-08 |
Oncomed Pharmaceuticals, Inc. |
Methods for treating melanoma
|
BR112013012040A2
(pt)
|
2010-11-15 |
2016-08-16 |
Five Prime Therapeutics Inc |
tratamento de câncer com dosagens elevadas de proteínas de fusão fdfr1 solúveis
|
JP5766296B2
(ja)
|
2010-12-23 |
2015-08-19 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
|
JOP20210044A1
(ar)
*
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
WO2012095514A1
(en)
|
2011-01-14 |
2012-07-19 |
Vivalis |
Recombinant protein production system
|
ES2549638T3
(es)
|
2011-02-28 |
2015-10-30 |
F. Hoffmann-La Roche Ag |
Proteínas de unión a antígeno
|
KR101572338B1
(ko)
|
2011-02-28 |
2015-11-26 |
에프. 호프만-라 로슈 아게 |
1가 항원 결합 단백질
|
EP3138581B1
(de)
|
2011-03-17 |
2019-01-02 |
The University of Birmingham |
Umgelenkte immuntherapie
|
CN103476795B
(zh)
|
2011-03-29 |
2016-07-06 |
罗切格利卡特公司 |
抗体Fc变体
|
US20150064171A1
(en)
|
2011-04-01 |
2015-03-05 |
Genentech, Inc. |
Combinations of akt inhibitor compounds and chemotheraeptuc agents, and methods of use
|
US9527925B2
(en)
|
2011-04-01 |
2016-12-27 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules binding to VEGF and ANG2
|
EP3549952A1
(de)
|
2011-04-20 |
2019-10-09 |
Acceleron Pharma Inc. |
Endoglinpolypeptide und verwendungen davon
|
WO2012151317A1
(en)
|
2011-05-03 |
2012-11-08 |
Genentech, Inc. |
Vascular disruption agents and uses thereof
|
WO2012172054A1
(en)
|
2011-06-16 |
2012-12-20 |
Scil Proteins Gmbh |
Modified multimeric ubiquitin proteins binding vegf-a
|
AR086823A1
(es)
|
2011-06-30 |
2014-01-22 |
Genentech Inc |
Formulaciones de anticuerpo anti-c-met, metodos
|
EP2732269B1
(de)
|
2011-07-12 |
2017-10-18 |
Epitomics, Inc. |
Facs-basiertes verfahren zur erzeugung einer antikörpersequenz
|
US9181532B2
(en)
|
2011-07-29 |
2015-11-10 |
Icon Genetics Gmbh |
Production of galactosylated N-glycans in plants
|
BR112014003599A2
(pt)
|
2011-08-17 |
2018-04-17 |
Genentech Inc |
método de inibição da angiogênese tumoral, método de supressão do crescimento tumoral e método de tratamento de tumor
|
EP2758073B1
(de)
|
2011-09-23 |
2018-10-31 |
OncoMed Pharmaceuticals, Inc. |
Vegf/dll4-bindende stoffe und ihre verwendung
|
WO2013050155A1
(en)
|
2011-10-04 |
2013-04-11 |
Icon Genetics Gmbh |
Nicotiana benthamiana plants deficient in fucosyltransferase activity
|
CN104168956A
(zh)
|
2011-10-11 |
2014-11-26 |
瓦西尼斯公司 |
臂板蛋白-4d结合分子用于调节血脑屏障渗透性的用途
|
AU2012323856B2
(en)
|
2011-10-13 |
2017-05-25 |
EyePoint Pharmaceuticals, Inc. |
Methods for treating Vascular Leak Syndrome and cancer
|
US8999325B2
(en)
*
|
2011-10-13 |
2015-04-07 |
Aerpio Therapeutics, Inc |
Treatment of ocular disease
|
WO2013082511A1
(en)
|
2011-12-02 |
2013-06-06 |
Genentech, Inc. |
Methods for overcoming tumor resistance to vegf antagonists
|
US9988424B2
(en)
|
2011-12-05 |
2018-06-05 |
Duke University |
Immunogens comprising human immunodeficiency virus V1/V2 polypeptides
|
US8790652B2
(en)
|
2011-12-06 |
2014-07-29 |
Vaccinex, Inc. |
Use of the combination of semaphorin-4D inhibitory molecules and VEGF inhibitory molecules to inhibit angiogenesis
|
BR112014015101A8
(pt)
|
2011-12-22 |
2021-06-08 |
Genentech Inc |
métodos para intensificar eficiência de etapas de cromatografia a jusante para purificação de anticorpos
|
WO2013091903A1
(en)
|
2011-12-22 |
2013-06-27 |
Novo Nordisk A/S |
Anti-crac channel antibodies
|
EP2797955A2
(de)
|
2011-12-30 |
2014-11-05 |
AbbVie Inc. |
Immunglobuline mit zweifacher variabler domäne gegen il-13 und/oder il-17
|
EP2802346B1
(de)
|
2012-01-13 |
2018-09-12 |
F.Hoffmann-La Roche Ag |
Biologische marker zur identifikation von patienten zur behandlung mit vegf-antagonisten
|
BR112014019579A2
(pt)
|
2012-02-10 |
2019-10-15 |
Genentech, Inc |
Anticorpo de cadeia única, polinucleotídeo, vetor, célula hospedeira, método de produção de um anticorpo de cadeia única, heteromultímero e método de produção do heteromultímero
|
EP2819700B1
(de)
|
2012-02-27 |
2016-12-21 |
Universitat de Barcelona |
Proteaseresistente verbindungen zur verwendung als shuttles durch die blut-hirn-schranke und shuttle-cargo-konstrukte
|
WO2013135602A2
(en)
|
2012-03-13 |
2013-09-19 |
F. Hoffmann-La Roche Ag |
Combination therapy for the treatment of ovarian cancer
|
ES2654424T3
(es)
|
2012-03-27 |
2018-02-13 |
F. Hoffmann-La Roche Ag |
Procedimiento para producir proteínas recombinantes con bajos niveles de DHNA (1,4-dihidroxi-2-naftoato)
|
US20150056190A1
(en)
|
2012-03-30 |
2015-02-26 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
CN107383197B
(zh)
|
2012-04-20 |
2021-12-10 |
美勒斯公司 |
用于产生免疫球蛋白样分子的方法和手段
|
WO2013170182A1
(en)
|
2012-05-11 |
2013-11-14 |
Synta Pharmaceuticals Corp. |
Treating cancer with an hsp90 inhibitory compound
|
US10494440B2
(en)
|
2012-05-11 |
2019-12-03 |
Vaccinex, Inc. |
Use of semaphorin-4D binding molecules to promote neurogenesis following stroke
|
AU2013267267B2
(en)
|
2012-05-31 |
2017-10-26 |
Genentech, Inc. |
Methods of treating cancer using PD-L1 axis binding antagonists and VEGF antagonists
|
SI3858405T1
(sl)
|
2012-06-01 |
2023-08-31 |
Novartis Ag |
Brizga
|
KR101909801B1
(ko)
|
2012-06-08 |
2018-10-18 |
에프. 호프만-라 로슈 아게 |
암의 치료를 위한 포스포이노시타이드 3 키나제 억제제 화합물 및 화학치료제의 돌연변이체 선택성 및 조합물
|
MX354862B
(es)
|
2012-06-27 |
2018-03-23 |
Hoffmann La Roche |
Método para la producción de entidades dirigidas altamente selectivas hechas a la medida y biespecíficas que contienen dos entidades de unión diferentes.
|
WO2014001325A1
(en)
|
2012-06-27 |
2014-01-03 |
F. Hoffmann-La Roche Ag |
Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof
|
JOP20200175A1
(ar)
|
2012-07-03 |
2017-06-16 |
Novartis Ag |
حقنة
|
PL3495387T3
(pl)
|
2012-07-13 |
2022-01-10 |
Roche Glycart Ag |
Dwuswoiste przeciwciała anty-VEGF/anty-ANG-2 i ich zastosowanie w leczeniu chorób naczyniowych oka
|
BR112015002681A2
(pt)
|
2012-08-07 |
2018-08-28 |
Genentech Inc |
método para tratar um paciente e kit
|
ES2705493T3
(es)
|
2012-09-19 |
2019-03-25 |
Hoffmann La Roche |
Procedimientos y composiciones para prevenir la incorporación errónea de norleucina en proteínas
|
CA2889638A1
(en)
|
2012-10-31 |
2014-05-08 |
Oncomed Pharmaceuticals, Inc. |
Methods and monitoring of treatment with a dll4 antagonist
|
RU2017137740A
(ru)
|
2012-11-01 |
2019-02-11 |
Эббви Инк. |
Анти-vegf/dll4-иммуноглобулины с двойными вариабельными доменами и их применения
|
WO2014074218A1
(en)
|
2012-11-12 |
2014-05-15 |
Redwood Bioscience, Inc. |
Compounds and methods for producing a conjugate
|
KR20150085064A
(ko)
|
2012-11-16 |
2015-07-22 |
더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 |
단백질 화학적 변형을 위한 피크테 스펭글러 결합
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
SG11201503566QA
(en)
|
2012-12-18 |
2015-09-29 |
Novartis Ag |
Compositions and methods that utilize a peptide tag that binds to hyaluronan
|
CA2898146C
(en)
|
2012-12-19 |
2020-12-01 |
Charles Andrew BOSWELL |
Methods and compositions for radiohalogen protein labeling
|
US9770426B2
(en)
|
2013-01-11 |
2017-09-26 |
Massachusetts Eye And Ear Infirmary |
CYP450 lipid metabolites reduce inflammation and angiogenesis
|
ES2774964T3
(es)
|
2013-02-04 |
2020-07-23 |
Vascular Biogenics Ltd |
Métodos para inducir la capacidad de respuesta a un agente antiangiogénico
|
US9745558B2
(en)
|
2013-02-18 |
2017-08-29 |
Vegenics Pty Limited |
VEGFR-3 ligand binding molecules and uses thereof
|
NZ751452A
(en)
|
2013-03-13 |
2020-04-24 |
Genentech Inc |
Antibody formulations
|
BR112015022529A2
(pt)
|
2013-03-15 |
2017-07-18 |
Genentech Inc |
meios de cultura de células e processos de produção de anticorpo
|
EP2970459A2
(de)
|
2013-03-15 |
2016-01-20 |
AbbVie Inc. |
Gegen il-1beta und il-17 gerichtete duale spezifische bindungsproteine
|
US9707154B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
KR102282134B1
(ko)
|
2013-04-29 |
2021-07-27 |
에프. 호프만-라 로슈 아게 |
인간 fcrn-결합 변형된 항체 및 사용 방법
|
AU2014268519A1
(en)
|
2013-05-23 |
2015-11-05 |
Five Prime Therapeutics, Inc. |
Methods of treating cancer
|
KR101541478B1
(ko)
*
|
2013-05-31 |
2015-08-05 |
동아쏘시오홀딩스 주식회사 |
항-vegf 항체 및 이를 포함하는 암 또는 신생혈관형성관련 질환의 예방, 진단 또는 치료용 약학 조성물
|
JP6611709B2
(ja)
|
2013-06-25 |
2019-11-27 |
バクシネックス インコーポレーティッド |
腫瘍成長および転移を阻害するための免疫調節療法との組み合わせでのセマフォリン−4d阻害分子の使用
|
SG10201912985RA
(en)
|
2013-07-12 |
2020-02-27 |
Ophthotech Corp |
Methods for treating or preventing ophthalmological conditions
|
CN107318267B
(zh)
|
2013-08-12 |
2021-08-17 |
豪夫迈·罗氏有限公司 |
用于治疗补体相关的病症的组合物和方法
|
US10617755B2
(en)
|
2013-08-30 |
2020-04-14 |
Genentech, Inc. |
Combination therapy for the treatment of glioblastoma
|
US10456470B2
(en)
|
2013-08-30 |
2019-10-29 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of glioblastoma
|
US10702608B2
(en)
|
2013-09-08 |
2020-07-07 |
Kodiak Sciences Inc. |
Factor VIII zwitterionic polymer conjugates
|
NZ630881A
(en)
|
2013-10-10 |
2016-03-31 |
Vaccinex Inc |
Use of semaphorin-4d binding molecules for treatment of atherosclerosis
|
KR20160044060A
(ko)
|
2013-10-11 |
2016-04-22 |
에프. 호프만-라 로슈 아게 |
다중특이적 도메인 교환된 통상의 가변 경쇄 항체
|
NZ630892A
(en)
|
2013-10-21 |
2016-03-31 |
Vaccinex Inc |
Use of semaphorin-4d binding molecules for treating neurodegenerative disorders
|
KR20220013459A
(ko)
|
2013-10-25 |
2022-02-04 |
악셀레론 파마 인코포레이티드 |
섬유화 질환을 치료하기 위한 엔도글린 펩티드
|
US10568951B2
(en)
|
2013-11-18 |
2020-02-25 |
Formycon Ag |
Pharmaceutical composition of an anti-VEGF antibody
|
CN105744935B
(zh)
|
2013-11-27 |
2022-09-30 |
雷德伍德生物科技股份有限公司 |
肼基-吡咯并化合物及用于生成缀合物的方法
|
CN105263959A
(zh)
*
|
2013-12-31 |
2016-01-20 |
财团法人生物技术开发中心 |
抗vegf抗体及其用途
|
CA2932364A1
(en)
|
2014-01-15 |
2015-07-23 |
F. Hoffmann-La Roche Ag |
Fc-region variants with improved protein a-binding
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
WO2015123241A1
(en)
|
2014-02-14 |
2015-08-20 |
Chi Andrew S |
Improved methods for the treatment of vascularizing cancers
|
EP3108255B1
(de)
|
2014-02-18 |
2020-08-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren und pharmazeutische zusammensetzungen zur behandlung von durch den nrp-1/obr-komplexsignalweg vermittelten krankheiten
|
EP3110941A4
(de)
|
2014-02-25 |
2017-10-18 |
Dr. Reddy's Laboratories Ltd. |
Verfahren zur modifizierung der galactosylierung und g0f-gehalt einer glycoproteinzusammensetzung durch glutaminergänzung
|
PT3116891T
(pt)
|
2014-03-10 |
2020-05-18 |
Richter Gedeon Nyrt |
Purificação de imunoglobulina utilizando passos de pré-limpeza
|
CR20160425A
(es)
|
2014-03-14 |
2017-05-26 |
Novartis Ag |
Moléculas de anticuerpos que se unen a lag-3 y usos de las mismas
|
JP2017516458A
(ja)
|
2014-03-24 |
2017-06-22 |
ジェネンテック, インコーポレイテッド |
c−met拮抗剤による癌治療及びc−met拮抗剤のHGF発現との相関
|
EP3126386A1
(de)
|
2014-03-31 |
2017-02-08 |
F. Hoffmann-La Roche AG |
Kombinationstherapie mit antiangiogenesewirkstoffen und ox40-bindenden agonisten
|
EP3137503A1
(de)
|
2014-05-01 |
2017-03-08 |
Genentech, Inc. |
Antifaktor-d-antikörpervarianten und verwendungen davon
|
EP3143044A1
(de)
|
2014-05-12 |
2017-03-22 |
Formycon AG |
Vorgefüllte spritze aus kunststoff mit einem vegf-antagonisten
|
JP2017515859A
(ja)
|
2014-05-15 |
2017-06-15 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
抗pd−1抗体と他の抗癌剤の組み合わせを使用する肺癌の処置
|
EP3151830A4
(de)
|
2014-06-06 |
2018-02-07 |
Redwood Bioscience, Inc. |
Anti-her2-antikörper-maytansin-konjugate und verfahren zur verwendung davon
|
US20170290876A1
(en)
|
2014-06-25 |
2017-10-12 |
Novartis Ag |
Compositions and methods for long acting proteins
|
WO2015198240A2
(en)
|
2014-06-25 |
2015-12-30 |
Novartis Ag |
Compositions and methods for long acting proteins
|
US9840553B2
(en)
|
2014-06-28 |
2017-12-12 |
Kodiak Sciences Inc. |
Dual PDGF/VEGF antagonists
|
KR102355306B1
(ko)
|
2014-07-09 |
2022-01-24 |
제넨테크, 인크. |
세포 은행의 해동 회수를 개선하는 ph 조정
|
EP3169801A1
(de)
|
2014-07-14 |
2017-05-24 |
F. Hoffmann-La Roche AG |
Diagnostische verfahren und zusammensetzungen zur behandlung von glioblastomen
|
US20170224777A1
(en)
|
2014-08-12 |
2017-08-10 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and a cancer vaccine
|
CA2957717C
(en)
|
2014-08-12 |
2021-10-19 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2 and integrin-binding-fc-fusion protein
|
CN105330739B
(zh)
*
|
2014-08-12 |
2020-12-25 |
中美华世通生物医药科技(武汉)有限公司 |
与人血管内皮生长因子特异性结合的抗体或其抗原结合片段及其用途
|
CN107206071A
(zh)
|
2014-09-13 |
2017-09-26 |
诺华股份有限公司 |
Alk抑制剂的联合疗法
|
KR20170057339A
(ko)
|
2014-09-15 |
2017-05-24 |
제넨테크, 인크. |
항체 제형
|
US20170209574A1
(en)
|
2014-10-03 |
2017-07-27 |
Novartis Ag |
Combination therapies
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
PE20171067A1
(es)
|
2014-10-14 |
2017-07-24 |
Novartis Ag |
Moleculas de anticuerpo que se unen a pd-l1 y usos de las mismas
|
WO2016061562A2
(en)
|
2014-10-17 |
2016-04-21 |
Kodiak Sciences Inc. |
Butyrylcholinesterase zwitterionic polymer conjugates
|
CA2959821A1
(en)
|
2014-10-24 |
2016-04-28 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compositions and methods for inducing phagocytosis of mhc class i positive cells and countering anti-cd47/sirpa resistance
|
AU2015338974B2
(en)
|
2014-10-31 |
2021-08-26 |
Oncomed Pharmaceuticals, Inc. |
Combination therapy for treatment of disease
|
CA2960297A1
(en)
|
2014-11-10 |
2016-05-19 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
CN107001482B
(zh)
|
2014-12-03 |
2021-06-15 |
豪夫迈·罗氏有限公司 |
多特异性抗体
|
RS62827B1
(sr)
|
2014-12-11 |
2022-02-28 |
Bayer Healthcare Llc |
Tretman staračke degeneracije žute mrlje koja ima malu aktivnu leziju neovaskularizacije sudovnjače
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
WO2016100882A1
(en)
|
2014-12-19 |
2016-06-23 |
Novartis Ag |
Combination therapies
|
SG11201704707PA
(en)
|
2014-12-23 |
2017-07-28 |
Genentech Inc |
Compositions and methods for treating and diagnosing chemotherapy-resistant cancers
|
BR112017014376A2
(pt)
|
2015-01-28 |
2018-05-02 |
Pfizer |
formulação aquosa estável de anticorpos antifator de crescimento endotelial vascular (vegf) e uso
|
MA42450A
(fr)
|
2015-03-09 |
2018-05-23 |
Intekrin Therapeutics Inc |
Méthodes de traitement de la stéatose hépatique non alcoolique et/ou de la lipodystrophie
|
SI3286315T1
(sl)
|
2015-04-24 |
2021-09-30 |
F. Hoffmann-La Roche Ag |
Postopek identifikacije bakterij, ki obsegajo vezavne polipeptide
|
US20180155429A1
(en)
|
2015-05-28 |
2018-06-07 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
US11078278B2
(en)
|
2015-05-29 |
2021-08-03 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
AU2016274584A1
(en)
|
2015-06-08 |
2018-01-04 |
Genentech, Inc. |
Methods of treating cancer using anti-OX40 antibodies and PD-1 axis binding antagonists
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
EP3858859A1
(de)
|
2015-07-14 |
2021-08-04 |
Bristol-Myers Squibb Company |
Verfahren zur behandlung von krebs mit immune checkpoint-hemmer; antikörper, bindet an programmierter zelltod-1-rezeptor (pd-1) oder programmierte tod ligand 1 (pd-l1)
|
EP3328418A1
(de)
|
2015-07-29 |
2018-06-06 |
Novartis AG |
Kombinationstherapien mit antikörpermolekülen gegen pd-1
|
WO2017019897A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
JP6916776B2
(ja)
|
2015-07-29 |
2021-08-11 |
アラーガン、インコーポレイテッドAllergan,Incorporated |
Ang−2に対する重鎖のみ抗体
|
PT3317301T
(pt)
|
2015-07-29 |
2021-07-09 |
Novartis Ag |
Terapias de associação compreendendo moléculas de anticorpo contra lag-3
|
HU231463B1
(hu)
|
2015-08-04 |
2024-01-28 |
Richter Gedeon Nyrt. |
Módszer rekombináns proteinek galaktóz tartalmának növelésére
|
CA2992788A1
(en)
|
2015-08-14 |
2017-02-23 |
Allergan, Inc. |
Heavy chain only antibodies to pdgf
|
CA2987644A1
(en)
*
|
2015-08-21 |
2017-03-02 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
EP3349796A4
(de)
|
2015-09-17 |
2019-05-29 |
ImmunoGen, Inc. |
Therapeutische kombinationen mit anti-folr1-immunkonjugaten
|
WO2017046140A1
(en)
|
2015-09-18 |
2017-03-23 |
Bayer Pharma Aktiengesellschaft |
Treatment regimens for dr and rvo in dependence of the extent of retinal ischemia
|
WO2017050793A1
(en)
|
2015-09-22 |
2017-03-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Polypeptides capable of inhibiting the binding between leptin and neuropilin-1
|
PE20181363A1
(es)
|
2015-09-23 |
2018-08-27 |
Genentech Inc |
Variantes optimizadas de anticuerpos anti-vegf
|
JP6967003B2
(ja)
|
2015-09-23 |
2021-11-17 |
メレオ バイオファーマ 5 インコーポレイテッド |
がんの処置のための方法および組成物
|
WO2017055321A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of fibroblasts in a tissue sample
|
WO2017055320A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of cytotoxic lymphocytes in a tissue sample
|
WO2017055324A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of cells of monocytic origin in a tissue sample
|
WO2017055327A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of endothelial cells in a tissue sample
|
WO2017055319A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of b cells in a tissue sample
|
WO2017055325A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of nk cells in a tissue sample
|
WO2017055326A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of myeloid dendritic cells in a tissue sample
|
WO2017055322A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of neutrophils in a tissue sample
|
JP6835836B2
(ja)
|
2015-10-13 |
2021-02-24 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
脈絡膜血管新生の処置のための方法及び医薬組成物
|
AU2016344133A1
(en)
|
2015-10-30 |
2018-05-17 |
Genentech, Inc. |
Anti-Factor D antibody formulations
|
CN108472382A
(zh)
|
2015-10-30 |
2018-08-31 |
豪夫迈·罗氏有限公司 |
抗-因子d抗体变体缀合物及其用途
|
MA43113B1
(fr)
|
2015-10-30 |
2021-06-30 |
Hoffmann La Roche |
Anticorps anti-htr a1 et méthodes d'utilisation de ceux-ci
|
EP3368074A2
(de)
|
2015-10-30 |
2018-09-05 |
Hoffmann-La Roche AG |
Anti-faktor-d-antikörper und -konjugate
|
WO2017079116A2
(en)
|
2015-11-03 |
2017-05-11 |
Janssen Biotech, Inc. |
Antibodies specifically binding pd-1 and tim-3 and their uses
|
EP3370764A4
(de)
|
2015-11-05 |
2019-07-17 |
The Regents of The University of California |
Mit lipidkonjugaten markierte zellen und verfahren zur verwendung davon
|
WO2017083306A1
(en)
|
2015-11-09 |
2017-05-18 |
R.P. Scherer Technologies, Llc |
Anti-cd22 antibody-maytansine conjugates and methods of use thereof
|
MX2018006171A
(es)
|
2015-11-18 |
2018-12-19 |
Formycon Ag |
Jeringa de plastico precargada que contiene un antagonista de vegf.
|
MX2018006092A
(es)
|
2015-11-18 |
2019-01-31 |
Formycon Ag |
Envase farmacéutico precargado que comprende una formulación líquida de un antagonista del vegf.
|
MX2018006139A
(es)
|
2015-11-18 |
2019-03-14 |
Sio2 Medical Products Inc |
Envase farmaceutico para formulaciones oftalmicas.
|
CA3007276C
(en)
|
2015-12-03 |
2021-12-28 |
Regeneron Pharmaceuticals, Inc. |
Use of vegf inhibitor to treat macular degeneration in a patient population
|
MX2018007423A
(es)
|
2015-12-17 |
2018-11-09 |
Novartis Ag |
Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas.
|
WO2017117464A1
(en)
|
2015-12-30 |
2017-07-06 |
Kodiak Sciences Inc. |
Antibodies and conjugates thereof
|
AU2017213103B2
(en)
|
2016-01-26 |
2022-08-11 |
Formycon Ag |
Liquid formulation of a VEGF antagonist
|
US10894823B2
(en)
|
2016-03-24 |
2021-01-19 |
Gensun Biopharma Inc. |
Trispecific inhibitors for cancer treatment
|
BR112018070139A2
(pt)
|
2016-03-29 |
2019-02-05 |
Geltor Inc |
expressão de proteínas em bactérias gram-negativas em que a razão entre o volume periplasmático e o volume citoplasmático é entre 0,5:1 e 10:1
|
CA3019921A1
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
CN109154027A
(zh)
|
2016-04-15 |
2019-01-04 |
豪夫迈·罗氏有限公司 |
用于监测和治疗癌症的方法
|
LT4019019T
(lt)
|
2016-05-20 |
2024-06-25 |
Biohaven Therapeutics Ltd. |
Riluzolo, riluzolo provaistų arba riluzolo analogų naudojimas kartu su imunoterapijos rūšimis vėžio formų gydymui
|
EP3482205A1
(de)
|
2016-07-08 |
2019-05-15 |
H. Hoffnabb-La Roche Ag |
Verwendung des humanen epididymisproteins 4 (he4) zur beurteilung des ansprechens auf eine behandlung von muc-16-positivem krebs
|
EP3481963A1
(de)
|
2016-07-08 |
2019-05-15 |
Genentech, Inc. |
Verfahren zur diagnose und behandlung von krebs mittels des expressionsstatus und mutationsstatus von nrf2 und nachgeschalteten zielgenen dieses gens
|
WO2018011166A2
(en)
|
2016-07-12 |
2018-01-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of myeloid dendritic cells in a tissue sample
|
BR112019001206A2
(pt)
|
2016-07-20 |
2019-06-25 |
Aerpio Therapeutics Inc |
anticorpos monoclonais humanizados que visam ve-ptp (hptp-ss)
|
CN106222129A
(zh)
*
|
2016-07-29 |
2016-12-14 |
广东东阳光药业有限公司 |
一种提高抗体纯度的细胞培养基和培养方法
|
WO2018018613A1
(zh)
|
2016-07-29 |
2018-02-01 |
广东东阳光药业有限公司 |
一种提高抗体纯度的细胞培养基和培养方法
|
TW201811369A
(zh)
|
2016-08-12 |
2018-04-01 |
美商建南德克公司 |
Mek抑制劑、pd-1軸抑制劑及vegf抑制劑之組合療法
|
US10919958B2
(en)
*
|
2016-08-23 |
2021-02-16 |
Medimmune Limited |
Anti-VEGF-A antibodies and uses thereof
|
WO2018070390A1
(ja)
|
2016-10-12 |
2018-04-19 |
第一三共株式会社 |
抗robo4抗体と他剤を含む組成物
|
US11192925B2
(en)
|
2016-10-19 |
2021-12-07 |
Adverum Biotechnologies, Inc. |
Modified AAV capsids and uses thereof
|
CN109071656B
(zh)
|
2017-01-05 |
2021-05-18 |
璟尚生物制药公司 |
检查点调节物拮抗剂
|
WO2018132516A1
(en)
|
2017-01-10 |
2018-07-19 |
Nodus Therapeutics |
Combination tumor treatment with an integrin-binding-fc fusion protein and immune modulator
|
US10350266B2
(en)
|
2017-01-10 |
2019-07-16 |
Nodus Therapeutics, Inc. |
Method of treating cancer with a multiple integrin binding Fc fusion protein
|
CN110546277B
(zh)
|
2017-03-01 |
2024-06-11 |
豪夫迈·罗氏有限公司 |
用于癌症的诊断和治疗方法
|
CA3057286A1
(en)
*
|
2017-03-24 |
2018-09-27 |
Council Of Scientific And Industrial Research |
A process for the purification of recombinant antibody fragments
|
US11253508B2
(en)
|
2017-04-03 |
2022-02-22 |
Coherus Biosciences, Inc. |
PPARy agonist for treatment of progressive supranuclear palsy
|
JOP20190245A1
(ar)
|
2017-04-20 |
2019-10-15 |
Novartis Ag |
أنظمة توصيل إطلاق مستدام تتضمن روابط بلا أثر لنقطة الربط
|
CN110636859B
(zh)
|
2017-05-19 |
2024-05-03 |
科学与工业研究委员会 |
用于产生重折叠的重组人源化兰尼单抗的方法
|
WO2018215580A1
(en)
|
2017-05-24 |
2018-11-29 |
Formycon Ag |
Method for sterilizing prefilled plastic syringes containing a vegf antagonist
|
US20200237997A1
(en)
|
2017-05-24 |
2020-07-30 |
Formycon Ag |
Sterilizable pre-filled pharmaceutical packages comprising a liquid formulation of a vegf-antagonist
|
EP3630062A2
(de)
|
2017-05-24 |
2020-04-08 |
SiO2 Medical Products, Inc. |
Sterilisierbare pharmazeutische verpackung für ophthalmische formulierungen
|
TW201904610A
(zh)
|
2017-06-14 |
2019-02-01 |
德商拜耳製藥公司 |
用於治療新生血管型青光眼之非抗體vegf拮抗劑
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
EP3641812A1
(de)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antikörpermoleküle gegen cd73 und verwendungen davon
|
TW201906635A
(zh)
|
2017-07-04 |
2019-02-16 |
日商第一三共股份有限公司 |
伴隨視細胞變性的視網膜變性的疾病用藥
|
WO2019020777A1
(en)
|
2017-07-26 |
2019-01-31 |
Formycon Ag |
LIQUID FORMULATION OF A VEGF ANTAGONIST
|
WO2019057946A1
(en)
|
2017-09-25 |
2019-03-28 |
F. Hoffmann-La Roche Ag |
MULTI-CYCLIC AROMATIC COMPOUNDS AS D-FACTOR INHIBITORS
|
US11180541B2
(en)
|
2017-09-28 |
2021-11-23 |
Geltor, Inc. |
Recombinant collagen and elastin molecules and uses thereof
|
CN111356480A
(zh)
|
2017-10-20 |
2020-06-30 |
脉管生物生长有限公司 |
用于抗血管生成剂疗法的诊断方法
|
EP3727468A4
(de)
|
2017-12-19 |
2021-09-22 |
Akouos, Inc. |
Aav-vermittelte abgabe von therapeutischen antikörpern an das innenohr
|
EP3731864A1
(de)
|
2017-12-29 |
2020-11-04 |
F. Hoffmann-La Roche SA |
Anti-vegf-antikörper und verfahren zur verwendung
|
CN110003328B
(zh)
*
|
2018-01-05 |
2022-04-19 |
百奥泰生物制药股份有限公司 |
一种长效低毒的重组抗vegf人源化单克隆抗体及其生产方法
|
CA3088355A1
(en)
|
2018-02-06 |
2019-08-15 |
F. Hoffmann-La Roche Ag |
Treatment of ophthalmologic diseases
|
EP3758737A4
(de)
|
2018-03-02 |
2022-10-12 |
Kodiak Sciences Inc. |
Il-6-antikörper und fusionskonstrukte und konjugate davon
|
WO2019173692A2
(en)
|
2018-03-09 |
2019-09-12 |
Agenus Inc. |
Anti-cd73 antibodies and methods of use thereof
|
JP7520366B2
(ja)
|
2018-04-16 |
2024-07-23 |
オンクオリティー ファーマシューティカルズ チャイナ リミテッド |
腫瘍療法の副作用の予防または治療方法
|
CN112739323A
(zh)
|
2018-05-10 |
2021-04-30 |
瑞泽恩制药公司 |
含有高浓度vegf受体融合蛋白的制剂
|
US11746157B2
(en)
|
2018-05-24 |
2023-09-05 |
Janssen Biotech, Inc. |
PSMA binding agents and uses thereof
|
US11519020B2
(en)
|
2018-05-25 |
2022-12-06 |
Regeneron Pharmaceuticals, Inc. |
Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
WO2019229116A1
(en)
|
2018-05-31 |
2019-12-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Intravitreal delivery of a decorin polypeptide for the treatment of choroidal neovascularisation
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
WO2020006511A1
(en)
|
2018-06-29 |
2020-01-02 |
Gensun Biopharma, Inc. |
Trispecific antagonists
|
HRP20240584T1
(hr)
|
2018-07-03 |
2024-07-19 |
Bristol-Myers Squibb Company |
Postupak proizvodnje rekombinantnih proteina
|
GB201811410D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
OX40 Binding molecules
|
CN109053895B
(zh)
|
2018-08-30 |
2020-06-09 |
中山康方生物医药有限公司 |
抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
|
WO2020068653A1
(en)
|
2018-09-24 |
2020-04-02 |
Aerpio Pharmaceuticals, Inc. |
MULTISPECIFIC ANTIBODIES THAT TARGET HPTP - β (VE-PTP) AND VEGF
|
US20210380923A1
(en)
|
2018-10-10 |
2021-12-09 |
Boehringer Ingelheim International Gmbh |
Method for membrane gas transfer in high density bioreactor culture
|
EP3867646A1
(de)
|
2018-10-18 |
2021-08-25 |
F. Hoffmann-La Roche AG |
Diagnostische und therapeutische verfahren für sarkomatoiden nierenkrebs
|
HU231514B1
(hu)
|
2018-11-07 |
2024-07-28 |
Richter Gedeon Nyrt. |
Sejttenyészetben előállított rekombináns glikoprotein glikozilációs mintázatának megváltoztatására szolgáló módszer
|
WO2020109343A1
(en)
|
2018-11-29 |
2020-06-04 |
F. Hoffmann-La Roche Ag |
Combination therapy for treatment of macular degeneration
|
CN109134651B
(zh)
*
|
2018-12-03 |
2019-02-22 |
上海复宏汉霖生物技术股份有限公司 |
一种抗vegf的单克隆抗体及其制备方法和应用
|
US20200207812A1
(en)
|
2018-12-07 |
2020-07-02 |
Coherus Biosciences, Inc. |
Methods for producing recombinant proteins
|
CN113226472B
(zh)
|
2018-12-17 |
2025-01-28 |
雷维托普有限公司 |
双免疫细胞衔接物
|
WO2020183424A1
(en)
|
2019-03-13 |
2020-09-17 |
Vascular Biogenics Ltd. |
Methods of anti-tumor therapy
|
KR20210145152A
(ko)
|
2019-04-01 |
2021-12-01 |
제넨테크, 인크. |
단백질-함유 제제들의 안정화를 위한 조성물들 및 방법들
|
HU231498B1
(hu)
|
2019-04-04 |
2024-05-28 |
Richter Gedeon Nyrt |
Immunglobulinok affinitás kromatográfiájának fejlesztése kötést megelőző flokkulálás alkalmazásával
|
SG11202111349QA
(en)
|
2019-04-12 |
2021-11-29 |
Geltor Inc |
Recombinant elastin and production thereof
|
MX2021012767A
(es)
|
2019-04-19 |
2021-11-18 |
Janssen Biotech Inc |
Metodos para tratar el cancer de prostata con un anticuerpo anti-psma/cd3.
|
TWI862583B
(zh)
|
2019-04-26 |
2024-11-21 |
美商愛德維仁生物科技公司 |
用於玻璃體內遞送之變異體aav蛋白殼
|
AU2020270376A1
(en)
|
2019-05-03 |
2021-10-07 |
Genentech, Inc. |
Methods of treating cancer with an anti-PD-L1 antibody
|
EP3965816A1
(de)
|
2019-05-06 |
2022-03-16 |
MedImmune Limited |
Kombination aus monalizumab, durwerb, chemotherapie und bevacizumab oder cetoxximab zur behandlung von kolorektalkarzinom
|
WO2020263312A1
(en)
|
2019-06-28 |
2020-12-30 |
Gensun Biopharma, Inc. |
ANTITUMOR ANTAGONIST CONSISTING OF A MUTATED TGFβ1 - RII EXTRACELLULAR DOMAIN AND AN IMMUNOGLOBULIN SCAFFOLD
|
CN114514311A
(zh)
|
2019-08-01 |
2022-05-17 |
百时美施贵宝公司 |
改进补料分批细胞培养物中蛋白质产量的方法
|
EP4031578A1
(de)
|
2019-09-18 |
2022-07-27 |
Novartis AG |
Entpd2-antikörper, kombinationstherapien und verfahren zur verwendung der antikörper und kombinationstherapien
|
EP4041312A4
(de)
|
2019-10-10 |
2023-12-20 |
Kodiak Sciences Inc. |
Verfahren zur behandlung einer augenstörung
|
US20240092883A1
(en)
|
2019-10-11 |
2024-03-21 |
Coherus Biosciences, Inc. |
Methods of purifying ranibizumab or a ranibizumab variant
|
WO2021072182A1
(en)
|
2019-10-11 |
2021-04-15 |
Coherus Biosciences, Inc. |
Methods for producing ranibizumab
|
US20230022576A1
(en)
|
2019-11-19 |
2023-01-26 |
Protalix Ltd. |
Removal of constructs from transformed cells
|
US20230027029A1
(en)
|
2019-11-25 |
2023-01-26 |
Akeso Biopharma, Inc. |
Anti-pd-1-anti-vegfa bispecific antibody, pharmaceutical composition and use thereof
|
EP4118235A1
(de)
|
2020-03-11 |
2023-01-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren zur bestimmung, ob ein patient eine zentrale seröse chorioretinopathie hat oder gefährdet ist, eine solche zu haben
|
KR20220152262A
(ko)
|
2020-03-13 |
2022-11-15 |
제넨테크, 인크. |
항-인터루킨-33 항체 및 이의 용도
|
US12091681B2
(en)
|
2020-03-27 |
2024-09-17 |
Mendus B.V. |
Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
|
CN115698717A
(zh)
|
2020-04-03 |
2023-02-03 |
基因泰克公司 |
癌症的治疗和诊断方法
|
EP4171617A1
(de)
|
2020-06-30 |
2023-05-03 |
Mendus B.V. |
Verwendung von zellen aus leukämie in eierstockkrebsimpfstoffen
|
WO2022013787A1
(en)
|
2020-07-16 |
2022-01-20 |
Novartis Ag |
Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules
|
CN114106190A
(zh)
*
|
2020-08-31 |
2022-03-01 |
普米斯生物技术(珠海)有限公司 |
一种抗vegf/pd-l1双特异性抗体及其用途
|
US20230357815A1
(en)
|
2020-09-22 |
2023-11-09 |
Bristol-Myers Squibb Company |
Methods for increasing productivity of therapeutic proteins
|
US20230374447A1
(en)
|
2020-10-05 |
2023-11-23 |
Protalix Ltd. |
Dicer-like knock-out plant cells
|
CA3198668A1
(en)
|
2020-10-15 |
2022-04-21 |
Genentech, Inc. |
Hyaluronic acid binding derivatives of versican (vg1) for long acting delivery of therapeutics
|
KR20230088781A
(ko)
|
2020-11-13 |
2023-06-20 |
제넨테크, 인크. |
고형 종양 치료를 위한 krasg12c 억제제 및 vegf 억제제를 포함하는 방법 및 조성물
|
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(es)
|
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Scherer Technologies Llc R P |
Enlazadores de escisión doble de glicósido para conjugados de anticuerpo y fármaco.
|
IL303317A
(en)
|
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Anti-vegf antibody constructs and related methods for treating vestibular schwannoma associated symptoms
|
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(zh)
|
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肿瘤疫苗接种方法
|
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(es)
|
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Proteinas de union a psma y usos de estas
|
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(en)
|
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Methods of vaccination and use of cd47 blockade
|
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(ja)
|
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|
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(ja)
|
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がんのための治療及び診断方法並びに組成物
|
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(es)
|
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Virus adenoasociado recombinante que tiene una capsida variante y su aplicacion.
|
US20220389120A1
(en)
|
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2022-12-08 |
Gensun Biopharma Inc. |
Multispecific antagonists
|
EP4363449A2
(de)
|
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Genentech, Inc. |
Verfahren und zusammensetzungen zur behandlung von krebs
|
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(en)
|
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Methods and compositions for the treatment of cancer
|
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(en)
|
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Bristol-Myers Squibb Company |
Cell culture methods for producing therapeutic proteins
|
WO2023016516A1
(zh)
|
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2023-02-16 |
信达生物制药(苏州)有限公司 |
抗vegf a和vegf c双特异性抗体及其用途
|
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(de)
|
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Vorhersage einer änderung in zusammenhang mit einer makulaflüssigkeit
|
US20240390869A1
(en)
|
2021-09-21 |
2024-11-28 |
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Methods of controlling the level of dissolved oxygen (do) in a solution comprising a recombinant protein in a storage container
|
WO2023080900A1
(en)
|
2021-11-05 |
2023-05-11 |
Genentech, Inc. |
Methods and compositions for classifying and treating kidney cancer
|
WO2023144973A1
(ja)
|
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2023-08-03 |
中外製薬株式会社 |
抗vegf抗体及びパクリタキセルと組み合わせて使用する抗pd-l1抗体を含む医薬組成物
|
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(de)
|
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OnQuality Pharmaceuticals China Ltd. |
Verfahren zur prävention oder behandlung von mit einem antineoplastischen mittel assoziierten erkrankungen oder störungen
|
MX2024009456A
(es)
|
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2024-08-09 |
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Construcciones de anticuerpos anti-vegf y metodos relacionados para el tratamiento de los sintomas asociados al schwannoma vestibular.
|
WO2023155905A1
(zh)
|
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2023-08-24 |
上海岸阔医药科技有限公司 |
化合物及其用途
|
WO2024040175A1
(en)
|
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2024-02-22 |
Pulmatrix Operating Company, Inc. |
Methods for treating cancer using inhaled angiogenesis inhibitor
|
WO2024051223A1
(zh)
|
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中山康方生物医药有限公司 |
药物组合及用途
|
WO2024186635A2
(en)
|
2023-03-03 |
2024-09-12 |
Celldex Therapeutics, Inc. |
Anti-stem cell factor (scf) and anti-thymic stromal lymphopoietin (tslp) antibodies and bispecific constructs
|
WO2024263904A1
(en)
|
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Methods for treatment of liver cancer
|
WO2024263195A1
(en)
|
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Genentech, Inc. |
Methods for treatment of liver cancer
|