PT1254134E - Derivados de 1,3-di-hidro-2h-indol-2-ona e sua utilizacao como ligandos para os receptores v1b ou v1b e v1a da arginina-vasopressina - Google Patents

Derivados de 1,3-di-hidro-2h-indol-2-ona e sua utilizacao como ligandos para os receptores v1b ou v1b e v1a da arginina-vasopressina

Info

Publication number: PT1254134E
Authority: PT; Portugal
Prior art keywords: receptors; vasopressin; arginine; indol; dihydro
Prior art date: 2000-01-25

Application number

PT01907687T

Other languages

English (en)

Inventor

Jean Wagnon

Claudine Serradeil-Le-Gal

Bruno Schoentjes

Original Assignee

Sanofi Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-25

Filing date

2001-01-24

Publication date

2003-11-28

2001-01-24 Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo

2003-11-28 Publication of PT1254134E publication Critical patent/PT1254134E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61P3/00—Drugs for disorders of the metabolism
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Cardiology (AREA)
Ophthalmology & Optometry (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Hematology (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Reproductive Health (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Gynecology & Obstetrics (AREA)
Dermatology (AREA)
Pregnancy & Childbirth (AREA)
Emergency Medicine (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)

PT01907687T 2000-01-25 2001-01-24 Derivados de 1,3-di-hidro-2h-indol-2-ona e sua utilizacao como ligandos para os receptores v1b ou v1b e v1a da arginina-vasopressina PT1254134E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0000958A FR2804115B1 (fr)	2000-01-25	2000-01-25	Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant

Publications (1)

Publication Number	Publication Date
PT1254134E true PT1254134E (pt)	2003-11-28

Family

ID=8846308

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT01907687T PT1254134E (pt)	2000-01-25	2001-01-24	Derivados de 1,3-di-hidro-2h-indol-2-ona e sua utilizacao como ligandos para os receptores v1b ou v1b e v1a da arginina-vasopressina

Country Status (13)

Country	Link
US (1)	US6624164B2 (pt)
EP (1)	EP1254134B1 (pt)
JP (1)	JP4861591B2 (pt)
AT (1)	ATE245644T1 (pt)
AU (1)	AU2001235596A1 (pt)
DE (1)	DE60100506T2 (pt)
DK (1)	DK1254134T3 (pt)
ES (1)	ES2203596T3 (pt)
FR (1)	FR2804115B1 (pt)
HU (1)	HU225157B1 (pt)
PT (1)	PT1254134E (pt)
TR (1)	TR200301723T4 (pt)
WO (1)	WO2001055134A2 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2805536B1 (fr) *	2000-02-25	2002-08-23	Sanofi Synthelabo	Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant
WO2005021534A1 (ja) *	2003-08-28	2005-03-10	Taisho Pharmaceutical Co., Ltd.	１，３−ジヒドロ−２ｈ−インドール−２−オン誘導体
US8580842B2 (en)	2003-09-30	2013-11-12	Abbott Gmbh & Co. Kg	Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
US20050070718A1 (en) *	2003-09-30	2005-03-31	Abbott Gmbh & Co. Kg	Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
US7414052B2 (en)	2004-03-30	2008-08-19	Wyeth	Phenylaminopropanol derivatives and methods of their use
US7517899B2 (en)	2004-03-30	2009-04-14	Wyeth	Phenylaminopropanol derivatives and methods of their use
WO2006070742A1 (ja) *	2004-12-27	2006-07-06	Kyoto University	麻薬性鎮痛剤の耐性形成抑制剤
JP5125501B2 (ja) *	2005-01-28	2013-01-23	大正製薬株式会社	１，３−ジヒドロ−２ｈ−インドール−２−オン化合物、及び芳香族複素環が縮合したピロリジン−２−オン化合物
DE102005014936A1 (de)	2005-03-24	2006-12-14	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
CA2602194A1 (en)	2005-03-24	2006-09-28	Abbott Gmbh & Co. Kg	Substituted oxindol derivatives, drugs containing said derivatives and the use thereof
DE102005014904A1 (de)	2005-03-26	2007-02-01	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
EP1957480A1 (de)	2005-12-02	2008-08-20	Abbott GmbH & Co. KG	Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung
EP2061769A1 (en) *	2006-08-26	2009-05-27	Abbott GmbH & Co. KG	Substituted benzimidazolone derivatives, medicaments comprising them and their use
DE102006040915A1 (de) *	2006-08-26	2008-03-20	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
US20080167286A1 (en) *	2006-12-12	2008-07-10	Abbott Laboratories	Pharmaceutical compositions and their methods of use
US8486979B2 (en) *	2006-12-12	2013-07-16	Abbvie Inc.	1,2,4 oxadiazole compounds and methods of use thereof
UY30846A1 (es)	2006-12-30	2008-07-31	Abbott Gmbh & Amp	Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos
EP2623504A1 (de)	2007-12-07	2013-08-07	Abbott GmbH & Co. KG	5,6-Disubstituierte Oxindol-Derivate und ihre Verwendung zur Herstellung eines Medikaments zur Behandlung von Vasopressin-abhängigen Erkrankungen
US8703774B2 (en)	2007-12-07	2014-04-22	AbbVie Deutschland GmbH & Co. KG	Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
JP5701607B2 (ja)	2007-12-07	2015-04-15	アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー	アミドメチル置換オキシインドール誘導体およびバソプレッシン依存性疾患の治療へのこれらの使用
BRPI0820668A2 (pt)	2007-12-07	2017-08-22	Abbott Gmbh & Co Kg	Derivados de oxindol substituídos por 5-halogênio e seu uso para tratar doenças dependentes de vasopressina
KR101570996B1 (ko)	2007-12-27	2015-11-23	아비에 도이치란트 게엠베하 운트 콤파니 카게	치환된 옥시인돌 유도체 및 바소프레신 의존성 질병을 치료하기 위한 이의 용도
FR2927625B1 (fr) *	2008-02-19	2010-03-12	Sanofi Aventis	Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique
FR2930249B1 (fr)	2008-04-21	2010-05-14	Sanofi Aventis	Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique.
US9040568B2 (en)	2009-05-29	2015-05-26	Abbvie Inc.	Pharmaceutical compositions for the treatment of pain

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5940149B2 (ja) *	1977-11-09	1984-09-28	大塚製薬株式会社	オキシインド−ル誘導体
JPS55129284A (en) *	1979-03-27	1980-10-06	Shionogi & Co Ltd	3-(1-imipazolyl)indolin-2-one
US4760083A (en) *	1986-04-10	1988-07-26	E. I. Dupont De Nemours & Company	3,3-disubstituted indolines
US5338755A (en) *	1990-07-31	1994-08-16	Elf Sanofi	N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present
FR2714378B1 (fr) *	1993-12-24	1996-03-15	Sanofi Sa	Dérivés de l'indol-2-one substitués en 3 par un groupe azoté, leur préparation, les compositions pharmaceutiques en contenant.
FR2757157B1 (fr)	1996-12-13	1999-12-31	Sanofi Sa	Derives d'indolin-2-one, procede pour leur preparation et compositions pharmaceutiques les contenant

2000
- 2000-01-25 FR FR0000958A patent/FR2804115B1/fr not_active Expired - Fee Related
2001
- 2001-01-24 HU HU0204157A patent/HU225157B1/hu not_active IP Right Cessation
- 2001-01-24 PT PT01907687T patent/PT1254134E/pt unknown
- 2001-01-24 AT AT01907687T patent/ATE245644T1/de active
- 2001-01-24 ES ES01907687T patent/ES2203596T3/es not_active Expired - Lifetime
- 2001-01-24 DE DE60100506T patent/DE60100506T2/de not_active Expired - Lifetime
- 2001-01-24 AU AU2001235596A patent/AU2001235596A1/en not_active Abandoned
- 2001-01-24 WO PCT/FR2001/000228 patent/WO2001055134A2/fr active IP Right Grant
- 2001-01-24 US US10/182,638 patent/US6624164B2/en not_active Expired - Fee Related
- 2001-01-24 DK DK01907687T patent/DK1254134T3/da active
- 2001-01-24 JP JP2001560993A patent/JP4861591B2/ja not_active Expired - Fee Related
- 2001-01-24 EP EP01907687A patent/EP1254134B1/fr not_active Expired - Lifetime
- 2001-01-24 TR TR2003/01723T patent/TR200301723T4/xx unknown

Also Published As

Publication number	Publication date
WO2001055134A2 (fr)	2001-08-02
DE60100506D1 (de)	2003-08-28
AU2001235596A1 (en)	2001-08-07
FR2804115B1 (fr)	2002-03-08
EP1254134B1 (fr)	2003-07-23
ATE245644T1 (de)	2003-08-15
FR2804115A1 (fr)	2001-07-27
DK1254134T3 (da)	2003-11-03
HUP0204157A3 (en)	2005-04-28
JP4861591B2 (ja)	2012-01-25
DE60100506T2 (de)	2004-05-13
HU225157B1 (en)	2006-07-28
EP1254134A2 (fr)	2002-11-06
ES2203596T3 (es)	2004-04-16
TR200301723T4 (tr)	2004-02-23
US20030139413A1 (en)	2003-07-24
WO2001055134A3 (fr)	2002-03-14
HUP0204157A2 (hu)	2003-04-28
JP2003523354A (ja)	2003-08-05
US6624164B2 (en)	2003-09-23

Publication	Publication Date	Title
PT1254134E (pt)	2003-11-28	Derivados de 1,3-di-hidro-2h-indol-2-ona e sua utilizacao como ligandos para os receptores v1b ou v1b e v1a da arginina-vasopressina
PT1255751E (pt)	2004-10-29	Derivados de 1,3-di-hidro-2h-indol-2-ona e a sua utilizacao enquanto ligandos dos receptores v1b ou v1b e v1a da arginina-vasopressina
MXPA03004549A (es)	2004-03-26	Derivados de 3-arilindola y su uso como agonistas del receptor cb2.
MXPA02009773A (es)	2003-06-17	Derivados de indolin-2-ona y su uso como ligandos de receptores de ocitocina.
TR200101961T2 (tr)	2001-12-21	1,2-halkalı kinolin türevleri
DE60204452D1 (de)	2005-07-07	Pyrazolo[1,5]pyridinderivate
NO20015226L (no)	2001-12-05	Tri-aryl syrederivater som PPAR reseptor ligander, farmasoytisk sammensetning omfattende samme og anvendelse av samme for fremstilling av medikament.
BR0107888A (pt)	2002-11-05	Pirrolidinas 1,3-dissubstituidas como antagonistas de alfa-2adrenorreceptor
TR199801041T2 (xx)	1998-08-21	Kanabinoid resept�r afinitesine sahip olan 3-pirazolkarboksamid t�revleri.
FI934274A0 (fi)	1993-09-29	N-sulfonyl-2-oxi-indolderivat, deras framstaellning och dessa innehaollande farmaceutiska kompositioner
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