KR100247853B1 - D-알파-아미노산의 제조방법 - Google Patents

D-알파-아미노산의 제조방법 Download PDF

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Publication number: KR100247853B1
Authority: KR; South Korea
Prior art keywords: carbamoyl; amino acid; enzyme; amino acids; dna
Prior art date: 1990-12-07

Application number

KR1019920701904A

Other languages

English (en)

Korean (ko)

Other versions

KR920703834A (ko

Inventor

난바히로까즈

야마다유끼오

다까노마사유끼

이께나까야스히로

다까하시사또미

야지마가즈요시

Original Assignee

후루타 다케시

가네가후치 가가쿠고교 가부시키가이샤

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-12-07

Filing date

1992-08-07

Publication date

2000-03-15

1992-08-07 Application filed by 후루타 다케시, 가네가후치 가가쿠고교 가부시키가이샤 filed Critical 후루타 다케시

1992-12-18 Publication of KR920703834A publication Critical patent/KR920703834A/ko

2000-03-15 Application granted granted Critical

2000-03-15 Publication of KR100247853B1 publication Critical patent/KR100247853B1/ko

Links

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CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
238000001179 sorption measurement Methods 0.000 description 1
238000003756 stirring Methods 0.000 description 1
125000001424 substituent group Chemical group 0.000 description 1
238000009210 therapy by ultrasound Methods 0.000 description 1
238000000844 transformation Methods 0.000 description 1
230000014621 translational initiation Effects 0.000 description 1
241001515965 unidentified phage Species 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Analytical Chemistry (AREA)
Biomedical Technology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Enzymes And Modification Thereof (AREA)

KR1019920701904A 1990-12-07 1992-08-07 D-알파-아미노산의 제조방법 KR100247853B1 (ko)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
JP40084890		1990-12-07
JP90-400848		1990-12-07
JP90-407922		1990-12-27
JP40792290		1990-12-27
JP91-78840		1991-04-11
JP7884091		1991-04-11
JP91-078840		1991-04-11

Publications (2)

Publication Number	Publication Date
KR920703834A KR920703834A (ko)	1992-12-18
KR100247853B1 true KR100247853B1 (ko)	2000-03-15

Family

ID=27302825

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
KR1019920701904A KR100247853B1 (ko)	1990-12-07	1992-08-07	D-알파-아미노산의 제조방법
KR1019997006525A KR100257212B1 (en)	1990-12-07	1999-07-19	Process for production of d-alpha-amino acids

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
KR1019997006525A KR100257212B1 (en)	1990-12-07	1999-07-19	Process for production of d-alpha-amino acids

Country Status (7)

Country	Link
US (2)	US5565344A (de)
EP (1)	EP0515698B1 (de)
KR (2)	KR100247853B1 (de)
CN (1)	CN1057568C (de)
DE (1)	DE69129899T2 (de)
ES (1)	ES2121001T3 (de)
WO (1)	WO1992010579A1 (de)

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US5824522A (en) *	1990-12-07	1998-10-20	Kanegafuchi Kagaku Kogyo Kabushiki Kaisha	Recombinant decarbamylases for producing D-α-amino acids
JP3392865B2 (ja) *	1991-06-12	2003-03-31	鐘淵化学工業株式会社	固定化酵素調製物およびＤ―α―アミノ酸の製造法
EP1568778A1 (de) *	1992-06-30	2005-08-31	Smithkline Beecham Plc	Hydantoinase aus Agrobacterium
ES2231772T3 (es) *	1992-08-10	2005-05-16	Kanegafuchi Kagaku Kogyo Kabushiki Kaisha	Adn codante para la descarbamilasa con termoestabilidad mejorada y uso del mismo.
EP0628637B1 (de) *	1992-10-05	2001-06-13	Kanegafuchi Chemical Industry Co., Ltd.	Verfahren zur herstellung von d-alpha-aminosäuren
DE4316928C2 (de) *	1993-05-19	1995-03-16	Degussa	Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
DE4328829A1 (de) *	1993-08-27	1995-03-02	Boehringer Mannheim Gmbh	Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung
IT1269321B (it) *	1994-04-15	1997-03-26	Eniricerche Spa	Mutanti stabili della d-n- -carbamilasi
IT1274167B (it) *	1994-04-15	1997-07-15	Eniricerche Spa	Procedimento per la produzione di d- -amminoacidi
CN1088473C (zh) *	1994-06-24	2002-07-31	钟渊化学工业株式会社	用复合固相酶制品生产d－氨基酸的方法
JP2924679B2 (ja) *	1994-12-26	1999-07-26	田辺製薬株式会社	Ｄ−リジンの製法
DE69535398T2 (de) *	1994-12-28	2007-10-31	Kanegafuchi Kagaku Kogyo K.K.	Verfahren zur herstellung einer d-n-carbamoyl-alpha-aminosäure
EP0735143B1 (de) *	1995-03-28	1998-11-18	Tanabe Seiyaku Co., Ltd.	Verfahren zur Herstellung von D-Aminosäuren
IT1276163B1 (it)	1995-11-23	1997-10-27	Eniricerche Spa	Procedimento migliorato per la preparazione di d-alfa-amminoacidi
US7101838B2 (en)	1997-08-05	2006-09-05	The Trustees Of Columbia University In The City Of New York	Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts
JP2001069981A (ja) *	1999-08-31	2001-03-21	Kanegafuchi Chem Ind Co Ltd	デカルバミラーゼの立体構造およびその利用法
AU5790801A (en) *	2000-01-21	2001-07-31	Biomarin Pharmaceutical Inc.	Flavobacterium heparinum expression system
US20020042537A1 (en)	2000-07-13	2002-04-11	Ajinomoto Co., Inc.	Method for producing lysine derivative
US6822116B2 (en) *	2002-05-24	2004-11-23	Biocatalytics, Inc.	Method for producing D-allo -isoleucine
US6830904B2 (en) *	2002-08-30	2004-12-14	Biocatalytics, Inc.	Methods for producing diastereomers of isoleucine
WO2005052145A2 (en) *	2003-10-07	2005-06-09	University Of Florida	Recombinant alkaliizing bacteria
WO2007040272A1 (ja) *	2005-10-06	2007-04-12	Kaneka Corporation	Ｄ－（４－アミノメチル）フェニルアラニン誘導体の製造法
CN104830824A (zh) *	2015-05-15	2015-08-12	南通荣泰生物科技有限公司	一种d型水解酶的生产工艺
CN106754558B (zh) *	2017-01-25	2020-12-08	中国人民解放军第二军医大学	一株产低温活性β-半乳糖苷酶的极地来源的细长赖氨酸芽孢杆菌及其应用

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1991
- 1991-12-06 EP EP92900888A patent/EP0515698B1/de not_active Expired - Lifetime
- 1991-12-06 US US07/917,111 patent/US5565344A/en not_active Expired - Lifetime
- 1991-12-06 ES ES92900888T patent/ES2121001T3/es not_active Expired - Lifetime
- 1991-12-06 WO PCT/JP1991/001696 patent/WO1992010579A1/ja active Application Filing
- 1991-12-06 DE DE69129899T patent/DE69129899T2/de not_active Expired - Fee Related
- 1991-12-07 CN CN91112793A patent/CN1057568C/zh not_active Expired - Fee Related
1992
- 1992-08-07 KR KR1019920701904A patent/KR100247853B1/ko not_active IP Right Cessation
1995
- 1995-06-07 US US08/479,638 patent/US5695968A/en not_active Expired - Lifetime
1999
- 1999-07-19 KR KR1019997006525A patent/KR100257212B1/ko not_active IP Right Cessation

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Also Published As

Publication number	Publication date
EP0515698B1 (de)	1998-07-29
EP0515698A4 (de)	1994-02-09
DE69129899D1 (de)	1998-09-03
CN1063310A (zh)	1992-08-05
DE69129899T2 (de)	1999-01-14
US5565344A (en)	1996-10-15
US5695968A (en)	1997-12-09
CN1057568C (zh)	2000-10-18
KR100257212B1 (en)	2000-05-15
WO1992010579A1 (en)	1992-06-25
ES2121001T3 (es)	1998-11-16
EP0515698A1 (de)	1992-12-02
KR920703834A (ko)	1992-12-18

Publication	Publication Date	Title
KR100247853B1 (ko)	2000-03-15	D-알파-아미노산의 제조방법
EP0610517B1 (de)	2004-10-20	Für eine decarbamylase mit verbesserter thermostabilität kodierende dna und ihre verwendung
RU2081173C1 (ru)	1997-06-10	Фрагмент днк, кодирующий полипептид с активностью нитрилгидратазы, рекомбинантная плазмидная днк, кодирующая полипептид со свойствами нитрилгидратазы, штамм бактерий eshcerichia coli - продуцент полипептида со свойствами нитрилгидратазы, способ получения полипептида со свойствами нитрилгидратазы
US20030113880A1 (en)	2003-06-19	DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids
EP0304021B1 (de)	1993-04-28	Acylaminosäure-Racemase, Herstellung und Verwendung
Lee et al.	1995	Thermostable D-hydantoinase from thermophilic Bacillus stearothermophilus SD-1: characteristics of purified enzyme
KR100244066B1 (ko)	2000-02-01	D-N-카르바모일-α-아미노산의 제조법
US7060485B2 (en)	2006-06-13	DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids
US5104800A (en)	1992-04-14	One-step cephalosporin c amidase enzyme
US5215897A (en)	1993-06-01	Process for producing L-amino acids
JP2902112B2 (ja)	1999-06-07	Ｄ―α―アミノ酸の製造法
US7977073B2 (en)	2011-07-12	Polynucleotide encoding a thermostable amide hydrolase and methods for producing an L-α-amino acid
JP2712331B2 (ja)	1998-02-10	アシルアミノ酸ラセマーゼ、その製造法および用途
JPH0822228B2 (ja)	1996-03-06	アミノ酸アミド加水分解酵素及びその使用
US5824522A (en)	1998-10-20	Recombinant decarbamylases for producing D-α-amino acids
US5902736A (en)	1999-05-11	Process for the production of D-α-amino acids by hydrolysis of the corresponding N-carbamyl derivative
JP5096911B2 (ja)	2012-12-12	５−置換ヒダントインラセマーゼ、これをコードするｄｎａ、組換えｄｎａ、形質転換された細胞、および、光学活性ｎ−カルバミルアミノ酸または光学活性アミノ酸の製造方法
JP4627039B2 (ja)	2011-02-09	アミダーゼ活性を有するポリペプチド及びその遺伝子
JP4081124B2 (ja)	2008-04-23	Ｄ−Ｎ−カルバモイル−α−アミノ酸の製造法
KR100244055B1 (ko)	2000-03-15	디-엔-카르바모일-알파-아미노산의 제조법
JPH08242863A (ja)	1996-09-24	新規なグルタミン酸デヒドロゲナーゼをコードする遺伝子及び該遺伝子を用いたグルタミン酸デヒドロゲナーゼの製造法

Legal Events

Date	Code	Title	Description
1992-08-07	PA0109	Patent application	Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19920807
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1996-12-06	A201	Request for examination
1996-12-06	PA0201	Request for examination	Patent event code: PA02012R01D Patent event date: 19961206 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19920807 Comment text: Patent Application
1998-12-15	E902	Notification of reason for refusal
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1999-03-19	E902	Notification of reason for refusal
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1999-07-19	A107	Divisional application of patent
1999-07-19	PA0104	Divisional application for international application	Comment text: Divisional Application for International Patent Patent event code: PA01041R01D Patent event date: 19990719
1999-09-29	E701	Decision to grant or registration of patent right
1999-09-29	PE0701	Decision of registration	Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19990929
1999-12-15	GRNT	Written decision to grant
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