ES2121001T3 - Procedimiento de produccion de d-alfa aminoacidos. - Google Patents
Procedimiento de produccion de d-alfa aminoacidos.Info
- Publication number
- ES2121001T3 ES2121001T3 ES92900888T ES92900888T ES2121001T3 ES 2121001 T3 ES2121001 T3 ES 2121001T3 ES 92900888 T ES92900888 T ES 92900888T ES 92900888 T ES92900888 T ES 92900888T ES 2121001 T3 ES2121001 T3 ES 2121001T3
- Authority
- ES
- Spain
- Prior art keywords
- amino acid
- amino acids
- production procedure
- alpha amino
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
LA INVENCION SE REFIERE A UN GEN QUE PERTENECE A AMIDOHIDROLASA DE AMINOACIDO D-N-CARBAMOILO-O CIDO D-NCARBAMOILO-OANTE QUE COMPRENDE UN FRAGMENTO DE ADN QUE CONTIENE EL GEN INTEGRADO EN UN VECTOR; UN MICROORGANISMO QUE PERTENECE AL GENERO ESCHERICHIA, PSEUDOMONAS, FLAVOBACTERIUM, BACILLUS, SERRATIA, CORYNEBACTERIUM O BREVIBACTERIUM Y TRANSFORMADO MEDIANTE LA INTEGRACION DEL PLASMIDO RECOMBINANTE EN EL MISMO; UN PROCESO PARA LA PRODUCCION DE AMIDOHIDROLASA DE AMINOACIDO D-N-CARBA-MOILO-O DOHIDROLASA DE AMINOACIDO D-N-CARBAMOILO-OISMO; Y UN PROCESO PARA LA PRODUCCION DE AMINOACIDO D-O ACCION DE LA AMIDOHIDROLASA. LA AMIDOHIDROLASA PUEDE UTILIZARSE TAMBIEN EN UN ESTADO INMOVILIZADO EN UN PORTADOR.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP40084890 | 1990-12-07 | ||
JP40792290 | 1990-12-27 | ||
JP7884091 | 1991-04-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2121001T3 true ES2121001T3 (es) | 1998-11-16 |
Family
ID=27302825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92900888T Expired - Lifetime ES2121001T3 (es) | 1990-12-07 | 1991-12-06 | Procedimiento de produccion de d-alfa aminoacidos. |
Country Status (7)
Country | Link |
---|---|
US (2) | US5565344A (es) |
EP (1) | EP0515698B1 (es) |
KR (2) | KR100247853B1 (es) |
CN (1) | CN1057568C (es) |
DE (1) | DE69129899T2 (es) |
ES (1) | ES2121001T3 (es) |
WO (1) | WO1992010579A1 (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5824522A (en) * | 1990-12-07 | 1998-10-20 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Recombinant decarbamylases for producing D-α-amino acids |
JP3392865B2 (ja) * | 1991-06-12 | 2003-03-31 | 鐘淵化学工業株式会社 | 固定化酵素調製物およびD―α―アミノ酸の製造法 |
EP1568778A1 (en) * | 1992-06-30 | 2005-08-31 | Smithkline Beecham Plc | Hydantoinase from agrobacterium |
ES2231772T3 (es) * | 1992-08-10 | 2005-05-16 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Adn codante para la descarbamilasa con termoestabilidad mejorada y uso del mismo. |
EP0628637B1 (en) * | 1992-10-05 | 2001-06-13 | Kanegafuchi Chemical Industry Co., Ltd. | Process for producing d-alpha-amino acids |
DE4316928C2 (de) * | 1993-05-19 | 1995-03-16 | Degussa | Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren |
DE4328829A1 (de) * | 1993-08-27 | 1995-03-02 | Boehringer Mannheim Gmbh | Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung |
IT1269321B (it) * | 1994-04-15 | 1997-03-26 | Eniricerche Spa | Mutanti stabili della d-n- -carbamilasi |
IT1274167B (it) * | 1994-04-15 | 1997-07-15 | Eniricerche Spa | Procedimento per la produzione di d- -amminoacidi |
CN1088473C (zh) * | 1994-06-24 | 2002-07-31 | 钟渊化学工业株式会社 | 用复合固相酶制品生产d-氨基酸的方法 |
JP2924679B2 (ja) * | 1994-12-26 | 1999-07-26 | 田辺製薬株式会社 | D−リジンの製法 |
DE69535398T2 (de) * | 1994-12-28 | 2007-10-31 | Kanegafuchi Kagaku Kogyo K.K. | Verfahren zur herstellung einer d-n-carbamoyl-alpha-aminosäure |
EP0735143B1 (en) * | 1995-03-28 | 1998-11-18 | Tanabe Seiyaku Co., Ltd. | Process for preparing D-amino acids |
IT1276163B1 (it) | 1995-11-23 | 1997-10-27 | Eniricerche Spa | Procedimento migliorato per la preparazione di d-alfa-amminoacidi |
US7101838B2 (en) | 1997-08-05 | 2006-09-05 | The Trustees Of Columbia University In The City Of New York | Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts |
JP2001069981A (ja) * | 1999-08-31 | 2001-03-21 | Kanegafuchi Chem Ind Co Ltd | デカルバミラーゼの立体構造およびその利用法 |
AU5790801A (en) * | 2000-01-21 | 2001-07-31 | Biomarin Pharmaceutical Inc. | Flavobacterium heparinum expression system |
US20020042537A1 (en) | 2000-07-13 | 2002-04-11 | Ajinomoto Co., Inc. | Method for producing lysine derivative |
US6822116B2 (en) * | 2002-05-24 | 2004-11-23 | Biocatalytics, Inc. | Method for producing D-allo -isoleucine |
US6830904B2 (en) * | 2002-08-30 | 2004-12-14 | Biocatalytics, Inc. | Methods for producing diastereomers of isoleucine |
WO2005052145A2 (en) * | 2003-10-07 | 2005-06-09 | University Of Florida | Recombinant alkaliizing bacteria |
WO2007040272A1 (ja) * | 2005-10-06 | 2007-04-12 | Kaneka Corporation | D-(4-アミノメチル)フェニルアラニン誘導体の製造法 |
CN104830824A (zh) * | 2015-05-15 | 2015-08-12 | 南通荣泰生物科技有限公司 | 一种d型水解酶的生产工艺 |
CN106754558B (zh) * | 2017-01-25 | 2020-12-08 | 中国人民解放军第二军医大学 | 一株产低温活性β-半乳糖苷酶的极地来源的细长赖氨酸芽孢杆菌及其应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1039757B (it) * | 1975-07-10 | 1979-12-10 | Snam Progetti | Complessi enzimatici atti a trasformare idantoine raceme in am minoacidi otticamente attivi e loro applicazione |
IT1109506B (it) * | 1978-05-23 | 1985-12-16 | Snam Progetti | Processo enzimatico-microbiologico per la produzione di amminoacidi otticamente attivi a partire da idantoine e/o carbamil-derivati racemi |
JPS5588697A (en) * | 1978-12-27 | 1980-07-04 | Ajinomoto Co Inc | Preparation of d-alpha-amino acid |
JPS5718793A (en) * | 1980-07-08 | 1982-01-30 | Kao Corp | Granulation of coal-water slurry |
EP0136359B1 (en) * | 1983-02-17 | 1991-04-03 | Kyowa Hakko Kogyo Kabushiki Kaisha | Process for preparing l-histidine |
JP2679031B2 (ja) * | 1986-07-16 | 1997-11-19 | 味の素株式会社 | アミノ酸の製造法及びアミノ酸生産菌 |
DE3786511T2 (de) * | 1986-09-17 | 1994-01-13 | Beecham Group Plc | Immobilisiertes Enzympräparat und seine Verwendung. |
JPH01320991A (ja) * | 1988-06-20 | 1989-12-27 | Kanegafuchi Chem Ind Co Ltd | D−ホモフエニルアラニン類の製造方法 |
-
1991
- 1991-12-06 EP EP92900888A patent/EP0515698B1/en not_active Expired - Lifetime
- 1991-12-06 US US07/917,111 patent/US5565344A/en not_active Expired - Lifetime
- 1991-12-06 ES ES92900888T patent/ES2121001T3/es not_active Expired - Lifetime
- 1991-12-06 WO PCT/JP1991/001696 patent/WO1992010579A1/ja active Application Filing
- 1991-12-06 DE DE69129899T patent/DE69129899T2/de not_active Expired - Fee Related
- 1991-12-07 CN CN91112793A patent/CN1057568C/zh not_active Expired - Fee Related
-
1992
- 1992-08-07 KR KR1019920701904A patent/KR100247853B1/ko not_active IP Right Cessation
-
1995
- 1995-06-07 US US08/479,638 patent/US5695968A/en not_active Expired - Lifetime
-
1999
- 1999-07-19 KR KR1019997006525A patent/KR100257212B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0515698B1 (en) | 1998-07-29 |
EP0515698A4 (es) | 1994-02-09 |
DE69129899D1 (de) | 1998-09-03 |
CN1063310A (zh) | 1992-08-05 |
DE69129899T2 (de) | 1999-01-14 |
US5565344A (en) | 1996-10-15 |
US5695968A (en) | 1997-12-09 |
CN1057568C (zh) | 2000-10-18 |
KR100257212B1 (en) | 2000-05-15 |
WO1992010579A1 (en) | 1992-06-25 |
EP0515698A1 (en) | 1992-12-02 |
KR920703834A (ko) | 1992-12-18 |
KR100247853B1 (ko) | 2000-03-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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