HRP20020938B1 - Tropane derivatives useful in therapy - Google Patents

Tropane derivatives useful in therapy

Info

Publication number: HRP20020938B1
Authority: HR; Croatia
Prior art keywords: therapy; optionally substituted; derivatives useful; tropane derivatives; fluorine atoms
Prior art date: 2000-05-26

Application number

HR20020938A

Other languages

English (en)

Croatian (hr)

Inventor

Perros Manoussos

Anthony Price David

Luiza Christa Stammen Blanda

Wood Anthony

Original Assignee

Pfizer Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-26

Filing date

2002-11-26

Publication date

2011-05-31

2000-05-26 Priority claimed from GB0014046A external-priority patent/GB0014046D0/en

2000-06-27 Priority claimed from GB0015835A external-priority patent/GB0015835D0/en

2002-11-26 Application filed by Pfizer Inc. filed Critical Pfizer Inc.

2005-02-28 Publication of HRP20020938A2 publication Critical patent/HRP20020938A2/hr

2011-05-31 Publication of HRP20020938B1 publication Critical patent/HRP20020938B1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P19/00—Drugs for skeletal disorders
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Obesity (AREA)
Oncology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
AIDS & HIV (AREA)
Psychiatry (AREA)
Molecular Biology (AREA)
Emergency Medicine (AREA)
Tropical Medicine & Parasitology (AREA)

HR20020938A 2000-05-26 2002-11-26 Tropane derivatives useful in therapy HRP20020938B1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0014046A GB0014046D0 (en)	2000-05-26	2000-05-26	Compounds useful in therapy
GB0015835A GB0015835D0 (en)	2000-06-27	2000-06-27	Compounds useful in therapy
PCT/IB2001/000806 WO2001090106A2 (en)	2000-05-26	2001-05-09	Tryasolyl tropane derivatives as ccr5 modulators

Publications (2)

Publication Number	Publication Date
HRP20020938A2 HRP20020938A2 (en)	2005-02-28
HRP20020938B1 true HRP20020938B1 (en)	2011-05-31

Family

ID=26244452

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20020938A HRP20020938B1 (en)	2000-05-26	2002-11-26	Tropane derivatives useful in therapy

Country Status (51)

Country	Link
EP (3)	EP1990341B1 (sl)
JP (2)	JP3693957B2 (sl)
KR (2)	KR100523501B1 (sl)
CN (2)	CN100355753C (sl)
AP (1)	AP1965A (sl)
AR (2)	AR028622A1 (sl)
AT (2)	ATE407134T1 (sl)
AU (2)	AU2001252482B2 (sl)
BG (1)	BG65966B1 (sl)
BR (1)	BRPI0110955B8 (sl)
CA (1)	CA2408909C (sl)
CR (1)	CR10145A (sl)
CU (1)	CU23288B7 (sl)
CY (3)	CY2008006I1 (sl)
CZ (1)	CZ299102B6 (sl)
DE (3)	DE122008000011I1 (sl)
DK (2)	DK1284974T3 (sl)
DZ (1)	DZ3464A1 (sl)
EA (2)	EA007580B1 (sl)
EE (1)	EE05110B1 (sl)
EG (1)	EG24137A (sl)
ES (3)	ES2215129T3 (sl)
FR (1)	FR08C0007I2 (sl)
GE (1)	GEP20063799B (sl)
HK (3)	HK1054927A1 (sl)
HR (1)	HRP20020938B1 (sl)
HU (1)	HU225810B1 (sl)
IL (2)	IL152531A0 (sl)
IS (1)	IS2511B (sl)
LT (1)	LTC1284974I2 (sl)
LU (1)	LU91417I2 (sl)
MA (1)	MA26902A1 (sl)
ME (1)	ME00555B (sl)
MX (1)	MXPA02011631A (sl)
MY (3)	MY131019A (sl)
NL (1)	NL300338I2 (sl)
NO (3)	NO327892B1 (sl)
NZ (1)	NZ521477A (sl)
OA (1)	OA12264A (sl)
PA (1)	PA8517101A1 (sl)
PE (1)	PE20011371A1 (sl)
PL (1)	PL200551B1 (sl)
PT (2)	PT1526134E (sl)
RS (2)	RS50904B (sl)
SI (2)	SI1526134T1 (sl)
SK (1)	SK286129B6 (sl)
TN (1)	TNSN01077A1 (sl)
TR (1)	TR200400541T4 (sl)
TW (1)	TWI230160B (sl)
UY (1)	UY26727A1 (sl)
WO (1)	WO2001090106A2 (sl)

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CN101712679B (zh) *	2008-10-08	2013-04-10	中国科学院上海药物研究所	一种酰胺类化合物、其药物组合物及其制备方法和用途
ES2564457T3 (es) *	2009-07-24	2016-03-22	Glaxosmithkline Llc	Derivados de azabiciclo[3,2,1]octilo para su uso en el tratamiento de VIH
CN102140104B (zh) *	2010-02-03	2014-11-12	中国科学院上海药物研究所	1-(3-(s)-氨基丙基)-哌啶-4-氨基酰胺类化合物、其药物组合物及其制备方法和用途
BR112012024522A2 (pt)	2010-04-02	2017-08-08	Phivco 1 Llc	combinação, uso de uma combinação, composição farmacêutica, forma de dosagem única , kit, e, método para tratar um distúrbio
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GEP20063799B (en)	2006-04-25
CY1108451T1 (el)	2014-04-09
ES2401812T3 (es)	2013-04-24
HK1054927A1 (en)	2003-12-19
FR08C0007I2 (fr)	2009-01-15
RS50904B (sr)	2010-08-31
EE05110B1 (et)	2008-12-15
LU91417I9 (sl)	2019-01-02
CY2008006I2 (el)	2009-11-04
JP2005194283A (ja)	2005-07-21
SK16432002A3 (sk)	2004-01-08
EP1526134A2 (en)	2005-04-27
KR100523501B1 (ko)	2005-10-25
NO327892B1 (no)	2009-10-12
NO20025227L (no)	2002-10-31
AR060159A2 (es)	2008-05-28
BG107140A (bg)	2003-05-30
EP1526134A3 (en)	2006-11-29
BG65966B1 (bg)	2010-07-30
NZ521477A (en)	2004-07-30
KR100548854B1 (ko)	2006-02-02
CY2022009I1 (el)	2022-05-27
IS2511B (is)	2009-05-15
LU91417I2 (fr)	2008-04-22
NO2020019I1 (no)	2020-06-30
CN1680371A (zh)	2005-10-12
AP2002002663A0 (en)	2002-12-31
PA8517101A1 (es)	2002-10-24
EG24137A (en)	2008-08-06
IS6565A (is)	2002-09-24
JP3693957B2 (ja)	2005-09-14
WO2001090106A3 (en)	2002-03-28
NO20025227D0 (no)	2002-10-31
EP1990341B1 (en)	2013-01-23
EE200200656A (et)	2004-06-15
JP4854970B2 (ja)	2012-01-18
SK286129B6 (sk)	2008-04-07
EA007580B1 (ru)	2006-12-29
EP1284974B1 (en)	2004-03-03
ME00555A (en)	2011-12-20
CN1279040C (zh)	2006-10-11
PT1526134E (pt)	2008-10-28
AP1965A (en)	2009-03-04
TR200400541T4 (tr)	2004-04-21
BR0110955A (pt)	2003-06-03
CR10145A (es)	2008-08-19
NL300338I1 (nl)	2008-05-01
OA12264A (en)	2003-11-10
CZ299102B6 (cs)	2008-04-23
AU5248201A (en)	2001-12-03
CA2408909C (en)	2006-06-27
CY2008006I1 (el)	2009-11-04
HUP0302474A2 (hu)	2003-11-28
MY156920A (en)	2016-04-15
EA005382B1 (ru)	2005-02-24
DE60102233T2 (de)	2005-01-27
HU225810B1 (en)	2007-10-29
ME00555B (me)	2011-12-20
PE20011371A1 (es)	2002-01-18
HUP0302474A3 (en)	2007-05-29
EP1990341A1 (en)	2008-11-12
DE122008000011I1 (de)	2008-06-05
DE60102233D1 (de)	2004-04-08
NO2010007I1 (no)	2010-04-08
NL300338I2 (nl)	2008-06-02
ATE260914T1 (de)	2004-03-15
ES2215129T3 (es)	2004-10-01
CA2408909A1 (en)	2001-11-29
DE60135685D1 (de)	2008-10-16
FR08C0007I1 (sl)	2008-04-25
LTC1284974I2 (lt)	2020-11-10
IL152531A0 (en)	2003-05-29
AU2001252482B2 (en)	2006-01-19
TWI230160B (en)	2005-04-01
HK1090836A1 (en)	2007-01-05
RS51436B (en)	2011-04-30
ATE407134T1 (de)	2008-09-15
HRP20020938A2 (en)	2005-02-28
CN1437599A (zh)	2003-08-20
BRPI0110955B8 (pt)	2021-05-25
MXPA02011631A (es)	2003-03-27
AU2001252482C1 (en)	2001-12-03
YU82202A (sh)	2005-11-28
UY26727A1 (es)	2001-12-28
CU23288B7 (es)	2008-06-30
MY153023A (en)	2014-12-31
JP2003534343A (ja)	2003-11-18
DK1526134T3 (da)	2008-11-17
RS20090438A (en)	2010-05-07
CZ20023806A3 (cs)	2004-01-14
MY131019A (en)	2007-07-31
MA26902A1 (fr)	2004-12-20
DK1284974T3 (da)	2004-06-07
EA200401056A1 (ru)	2005-04-28
TNSN01077A1 (fr)	2005-11-10
WO2001090106A2 (en)	2001-11-29
CY2022009I2 (el)	2022-05-27
HK1078573A1 (en)	2006-03-17
PT1284974E (pt)	2004-06-30
EA200201141A1 (ru)	2003-04-24
ES2311126T3 (es)	2009-02-01
AR028622A1 (es)	2003-05-14
DZ3464A1 (sl)	2001-11-29
SI1284974T1 (sl)	2004-08-31
LTPA2008004I1 (lt)	2020-07-27
KR20030004417A (ko)	2003-01-14
IL152531A (en)	2010-05-17
SI1526134T1 (sl)	2008-12-31
PL359267A1 (en)	2004-08-23
NO2010007I2 (no)	2013-09-09
EP1526134B1 (en)	2008-09-03
KR20050046743A (ko)	2005-05-18
EP1284974A2 (en)	2003-02-26
PL200551B1 (pl)	2009-01-30
CN100355753C (zh)	2007-12-19
BRPI0110955B1 (pt)	2016-06-28

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