ES8504774A1 - Procedimiento para preparar derivados de 2-piperacinil-quinazolina - Google Patents
Procedimiento para preparar derivados de 2-piperacinil-quinazolinaInfo
- Publication number
- ES8504774A1 ES8504774A1 ES527164A ES527164A ES8504774A1 ES 8504774 A1 ES8504774 A1 ES 8504774A1 ES 527164 A ES527164 A ES 527164A ES 527164 A ES527164 A ES 527164A ES 8504774 A1 ES8504774 A1 ES 8504774A1
- Authority
- ES
- Spain
- Prior art keywords
- piperazinyl
- pharmaceutical compositions
- compositions containing
- quinazoline derivatives
- quinazoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 2-PIPERACINIL-QUINAZOLINA, EN PARTICULAR PARA LA PRODUCCION DE UNA 2-(N-FENILALQUIL-,-N-BENZOILALQUIL- O -N-FENOXIALQUIL-PIPERACINO- O SUS SALES DE ADICION DE ACIDOS.CONSISTE EN HACER REACCIONAR UNA QUINAZOLINA APROPIADA QUE LLEVA EN LA POSICION 2 UN GRUPO SUSCEPTIBLE DE SER ELIMINADO, CON UNA APROPIADA N-FENILALQUIL-, N-BENZOILALQUIL- O N-FENOXIALQUIL-PIPERAZINA, Y EN RECUPERAR EL COMPUESTO RESULTANTE EN FORMA DE BASE LIBRE O EN FORMA DE SAL DE ADICION DE ACIDO.DE APLICACION EN FARMACIA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH6614/82A CH651027A5 (de) | 1982-11-12 | 1982-11-12 | Heterocyclische verbindungen, ihre herstellung und verwendung. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES527164A0 ES527164A0 (es) | 1985-05-01 |
| ES8504774A1 true ES8504774A1 (es) | 1985-05-01 |
Family
ID=4312330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES527164A Expired ES8504774A1 (es) | 1982-11-12 | 1983-11-10 | Procedimiento para preparar derivados de 2-piperacinil-quinazolina |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4588725A (es) |
| JP (1) | JPS59101470A (es) |
| AU (1) | AU576739B2 (es) |
| BE (1) | BE898151A (es) |
| CA (1) | CA1209994A (es) |
| CH (1) | CH651027A5 (es) |
| DE (1) | DE3339943A1 (es) |
| DK (1) | DK158514C (es) |
| ES (1) | ES8504774A1 (es) |
| FI (1) | FI79303C (es) |
| FR (1) | FR2536072B1 (es) |
| GB (1) | GB2130207B (es) |
| HU (1) | HU193188B (es) |
| IE (1) | IE56229B1 (es) |
| IL (1) | IL70189A (es) |
| IT (1) | IT1170578B (es) |
| NL (1) | NL8303821A (es) |
| NZ (1) | NZ206224A (es) |
| PH (1) | PH21835A (es) |
| PT (1) | PT77638B (es) |
| SE (1) | SE460668B (es) |
| ZA (1) | ZA838435B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0647540B2 (ja) * | 1985-07-16 | 1994-06-22 | エーザイ株式会社 | 虚血性心疾患・不整脈治療・予防剤 |
| JP2561689B2 (ja) * | 1986-02-24 | 1996-12-11 | 三井石油化学工業株式会社 | 神経疾患用治療薬 |
| EP0799617A3 (en) * | 1986-02-24 | 1997-11-12 | Mitsui Petrochemical Industries, Ltd. | Therapeutic agent for neurological diseases |
| US4877790A (en) * | 1987-12-15 | 1989-10-31 | Kanebo Limited | Quinazoline derivative, processes for its production, and cerebral dysfunction remedying agent comprising it as active ingredient |
| US4994460A (en) * | 1989-06-01 | 1991-02-19 | Bristol-Myers Squibb Co. | Agents for treatment of brain ischemia |
| EP0538693A3 (en) * | 1991-10-23 | 1994-08-17 | Squibb & Sons Inc | Stereoselective preparation of halophenyl alcohols |
| TW334434B (en) * | 1995-05-16 | 1998-06-21 | Kanebo Ltd | Novel quinazoline compound and anti-tumor agent |
| WO2005042501A1 (en) * | 2003-11-03 | 2005-05-12 | Warner-Lambert Company Llc | Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL129219C (es) * | 1965-12-16 | |||
| GB1199768A (en) * | 1966-10-31 | 1970-07-22 | Pfizer & Co C | Nitrogen Heterocycles and process for their preparation |
| US3517005A (en) * | 1967-10-26 | 1970-06-23 | Pfizer & Co C | Certain 2- and 4-substituted quinazolines |
| GB1187680A (en) * | 1967-11-15 | 1970-04-15 | Science Union & Cie | New Heterocyclic Substituted Piperazines |
| GB1369379A (en) * | 1972-04-07 | 1974-10-09 | Science Union & Cie | Benzodioxole derivatives and processes for preparing them |
| GB1553436A (en) * | 1976-09-17 | 1979-09-26 | Bellon R Lab | Derivatives of pipemidic acid |
| US4287341A (en) * | 1979-11-01 | 1981-09-01 | Pfizer Inc. | Alkoxy-substituted-6-chloro-quinazoline-2,4-diones |
| FI70411C (fi) * | 1980-12-29 | 1986-09-19 | Pfizer | Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat |
-
1982
- 1982-11-12 CH CH6614/82A patent/CH651027A5/de not_active IP Right Cessation
-
1983
- 1983-11-03 FR FR8317615A patent/FR2536072B1/fr not_active Expired
- 1983-11-04 FI FI834061A patent/FI79303C/fi not_active IP Right Cessation
- 1983-11-04 DE DE19833339943 patent/DE3339943A1/de not_active Withdrawn
- 1983-11-04 BE BE1/10899A patent/BE898151A/fr not_active IP Right Cessation
- 1983-11-07 NL NL8303821A patent/NL8303821A/nl not_active Application Discontinuation
- 1983-11-08 IT IT49298/83A patent/IT1170578B/it active
- 1983-11-10 GB GB08330016A patent/GB2130207B/en not_active Expired
- 1983-11-10 US US06/550,909 patent/US4588725A/en not_active Expired - Fee Related
- 1983-11-10 HU HU833857A patent/HU193188B/hu not_active IP Right Cessation
- 1983-11-10 DK DK514283A patent/DK158514C/da not_active IP Right Cessation
- 1983-11-10 PT PT77638A patent/PT77638B/pt not_active IP Right Cessation
- 1983-11-10 IL IL70189A patent/IL70189A/xx unknown
- 1983-11-10 AU AU21147/83A patent/AU576739B2/en not_active Ceased
- 1983-11-10 ES ES527164A patent/ES8504774A1/es not_active Expired
- 1983-11-10 NZ NZ206224A patent/NZ206224A/en unknown
- 1983-11-11 ZA ZA838435A patent/ZA838435B/xx unknown
- 1983-11-11 SE SE8306225A patent/SE460668B/sv not_active IP Right Cessation
- 1983-11-11 JP JP58213151A patent/JPS59101470A/ja active Pending
- 1983-11-11 PH PH29827A patent/PH21835A/en unknown
- 1983-11-11 IE IE2626/83A patent/IE56229B1/xx unknown
- 1983-11-14 CA CA000441087A patent/CA1209994A/en not_active Expired
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