DK1849762T3 - Substituerede biphenylcarboxylsyrer og derivater deraf - Google Patents

Substituerede biphenylcarboxylsyrer og derivater deraf

Info

Publication number: DK1849762T3
Authority: DK; Denmark
Prior art keywords: derivatives; biphenylcarboxylic acids; substituted biphenylcarboxylic; substituted; acids
Prior art date: 2006-04-21

Application number

DK06112938T

Other languages

Danish (da)

English (en)

Inventor

Francis Wilson

Alison Reid

Valerie Reader

Richard John Harrison

Mihiro Sunose

Remedios Hernandez-Perni

Jeremy Major

Cyrille Boussard

Kathryn Smelt

Jess Taylor

Adeline Leformal

Andrew Cansfield

Svenja Burckhardt

Original Assignee

Cellzome Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-21

Filing date

2006-04-21

Publication date

2009-10-12

2006-04-21 Application filed by Cellzome Ltd filed Critical Cellzome Ltd

2009-10-12 Application granted granted Critical

2009-10-12 Publication of DK1849762T3 publication Critical patent/DK1849762T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK06112938T 2006-04-21 2006-04-21 Substituerede biphenylcarboxylsyrer og derivater deraf DK1849762T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP06112938A EP1849762B1 (en)	2006-04-21	2006-04-21	Substituted biphenyl carboxylic acids and derivatives thereof

Publications (1)

Publication Number	Publication Date
DK1849762T3 true DK1849762T3 (da)	2009-10-12

Family

ID=36688012

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK06112938T DK1849762T3 (da)	2006-04-21	2006-04-21	Substituerede biphenylcarboxylsyrer og derivater deraf

Country Status (35)

Country	Link
US (1)	US7557244B2 (xx)
EP (2)	EP1849762B1 (xx)
JP (1)	JP5479088B2 (xx)
KR (1)	KR101542255B1 (xx)
CN (1)	CN101687758B (xx)
AP (1)	AP2008004656A0 (xx)
AR (1)	AR060568A1 (xx)
AU (1)	AU2007240335B2 (xx)
BR (1)	BRPI0710656A2 (xx)
CA (1)	CA2650006C (xx)
CR (2)	CR10375A (xx)
CY (1)	CY1109399T1 (xx)
DE (1)	DE602006007810D1 (xx)
DK (1)	DK1849762T3 (xx)
EA (1)	EA016129B9 (xx)
ES (2)	ES2328616T3 (xx)
GE (1)	GEP20115269B (xx)
GT (1)	GT200900120A (xx)
IL (2)	IL194852A0 (xx)
MA (1)	MA30475B1 (xx)
MX (1)	MX2008013445A (xx)
MY (1)	MY148953A (xx)
NO (1)	NO20084517L (xx)
NZ (1)	NZ573000A (xx)
PE (1)	PE20080364A1 (xx)
PL (1)	PL1849762T3 (xx)
PT (1)	PT1849762E (xx)
SI (1)	SI1849762T1 (xx)
SM (1)	SMP200800061B (xx)
TN (1)	TNSN08413A1 (xx)
TW (1)	TWI399362B (xx)
UA (1)	UA95952C2 (xx)
UY (1)	UY30301A1 (xx)
WO (1)	WO2007124394A1 (xx)
ZA (1)	ZA200809856B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2702959C (en)	2007-10-19	2016-07-26	Janssen Pharmaceutica Nv	Carbon linked modulators of .gamma.-secretase
ATE543799T1 (de)	2007-10-19	2012-02-15	Janssen Pharmaceutica Nv	Piperidinyl- und piperazinylmodulatoren von g- sekretase
CN101903334A (zh) *	2007-10-19	2010-12-01	詹森药业有限公司	Gsm中间体
KR20100082351A (ko) *	2007-10-19	2010-07-16	얀센 파마슈티카 엔.브이.	γ-세크레타아제의 아민 결합된 조절제
US20110092554A1 (en) *	2007-11-19	2011-04-21	Richard Chesworth	1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders
JP2011507909A (ja)	2007-12-20	2011-03-10	エンビボファーマシューティカルズインコーポレイテッド	四置換ベンゼン
EP2488031A4 (en)	2009-10-16	2014-07-23	Merck Sharp & Dohme	DIARYL ETHER DERIVATIVES AS A NOTCH-PROOFING GAMMETRETASE INHIBITOR
US8785481B2 (en)	2010-09-29	2014-07-22	Merck Sharp & Dohme Corp.	Ether benzotriazole derivatives
WO2012119035A1 (en) *	2011-03-03	2012-09-07	Treventis Corporation	Anti-amyloid compounds and methods
WO2015109109A1 (en)	2014-01-15	2015-07-23	Forum Pharmaceuticals Inc.	Fused morpholinopyrimidines and methods of use thereof
WO2016201168A1 (en)	2015-06-10	2016-12-15	Forum Pharmceuticals Inc.	Oxadiazine compounds and methods of use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5877399A (en) *	1994-01-27	1999-03-02	Johns Hopkins University	Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
JP3802581B2 (ja) *	1995-03-01	2006-07-26	富山化学工業株式会社	新規なビフェニル誘導体またはその塩およびそれらを含有する抗炎症剤
JP2003530437A (ja) *	2000-04-13	2003-10-14	マヨファウンデーションフォーメディカルエデュケーションアンドリサーチ	Ａβ４２低下物質
DE10131899A1 (de)	2001-07-04	2003-02-27	Boehringer Ingelheim Pharma	In vitro-Screening-Assay für gamma-Secretase
NZ537206A (en) *	2002-06-27	2007-06-29	Astellas Pharma Inc	Aminoalcohol derivatives
GB0305918D0 (en) *	2003-03-14	2003-04-23	Glaxo Group Ltd	Novel compounds
WO2005110963A1 (en) *	2004-05-19	2005-11-24	Cellzome Ag	(biphenyl-3-yl)-carboxylic acids and derivatives thereof and their use in therapy
GB0416508D0 (en) *	2004-07-23	2004-08-25	Merck Sharp & Dohme	Therapeutic agents
JPWO2006022237A1 (ja) *	2004-08-24	2008-05-08	キッセイ薬品工業株式会社	脂肪肝の予防または治療剤
WO2007039736A1 (en) *	2005-10-06	2007-04-12	Astrazeneca Ab	Novel compounds

2006
- 2006-04-21 PL PL06112938T patent/PL1849762T3/pl unknown
- 2006-04-21 PT PT06112938T patent/PT1849762E/pt unknown
- 2006-04-21 ES ES06112938T patent/ES2328616T3/es active Active
- 2006-04-21 DK DK06112938T patent/DK1849762T3/da active
- 2006-04-21 DE DE602006007810T patent/DE602006007810D1/de active Active
- 2006-04-21 SI SI200630391T patent/SI1849762T1/sl unknown
- 2006-04-21 EP EP06112938A patent/EP1849762B1/en not_active Not-in-force
2007
- 2007-04-20 PE PE2007000496A patent/PE20080364A1/es active IP Right Grant
- 2007-04-20 KR KR1020087028566A patent/KR101542255B1/ko not_active IP Right Cessation
- 2007-04-20 SM SM200800061T patent/SMP200800061B/it unknown
- 2007-04-20 BR BRPI0710656-4A patent/BRPI0710656A2/pt not_active IP Right Cessation
- 2007-04-20 EP EP07760976A patent/EP2021314B1/en active Active
- 2007-04-20 TW TW096114160A patent/TWI399362B/zh not_active IP Right Cessation
- 2007-04-20 UY UY30301A patent/UY30301A1/es unknown
- 2007-04-20 CN CN200780018586.2A patent/CN101687758B/zh not_active Expired - Fee Related
- 2007-04-20 CA CA2650006A patent/CA2650006C/en not_active Expired - Fee Related
- 2007-04-20 US US11/737,938 patent/US7557244B2/en not_active Expired - Fee Related
- 2007-04-20 EA EA200802172A patent/EA016129B9/ru not_active IP Right Cessation
- 2007-04-20 UA UAA200813476A patent/UA95952C2/ru unknown
- 2007-04-20 GE GEAP200710983A patent/GEP20115269B/en unknown
- 2007-04-20 AR ARP070101725A patent/AR060568A1/es not_active Application Discontinuation
- 2007-04-20 MX MX2008013445A patent/MX2008013445A/es active IP Right Grant
- 2007-04-20 AU AU2007240335A patent/AU2007240335B2/en not_active Ceased
- 2007-04-20 NZ NZ573000A patent/NZ573000A/en not_active IP Right Cessation
- 2007-04-20 AP AP2008004656A patent/AP2008004656A0/xx unknown
- 2007-04-20 MY MYPI20084201A patent/MY148953A/en unknown
- 2007-04-20 WO PCT/US2007/067039 patent/WO2007124394A1/en active Application Filing
- 2007-04-20 ES ES07760976T patent/ES2400530T3/es active Active
- 2007-04-20 JP JP2009506782A patent/JP5479088B2/ja not_active Expired - Fee Related
2008
- 2008-10-17 TN TNP2008000413A patent/TNSN08413A1/en unknown
- 2008-10-17 CR CR10375A patent/CR10375A/es not_active Application Discontinuation
- 2008-10-22 IL IL194852A patent/IL194852A0/en unknown
- 2008-10-22 IL IL194790A patent/IL194790A/en not_active IP Right Cessation
- 2008-10-27 NO NO20084517A patent/NO20084517L/no not_active Application Discontinuation
- 2008-11-19 ZA ZA200809856A patent/ZA200809856B/xx unknown
- 2008-11-20 MA MA31395A patent/MA30475B1/fr unknown
- 2008-11-21 CR CR10451A patent/CR10451A/es not_active Application Discontinuation
2009
- 2009-05-11 GT GT200900120A patent/GT200900120A/es unknown
- 2009-09-21 CY CY20091100982T patent/CY1109399T1/el unknown

Also Published As

Publication number	Publication date
US20070293567A1 (en)	2007-12-20
EP1849762B1 (en)	2009-07-15
KR101542255B1 (ko)	2015-08-06
IL194852A0 (en)	2009-08-03
CA2650006A1 (en)	2007-11-01
ES2328616T3 (es)	2009-11-16
EP2021314A1 (en)	2009-02-11
IL194790A (en)	2012-12-31
DE602006007810D1 (de)	2009-08-27
SMAP200800061A (it)	2008-11-19
UY30301A1 (es)	2007-08-31
AU2007240335A1 (en)	2007-11-01
GT200900120A (es)	2009-11-16
GEP20115269B (en)	2011-08-25
PE20080364A1 (es)	2008-05-16
AU2007240335B2 (en)	2013-05-02
MY148953A (en)	2013-06-14
UA95952C2 (ru)	2011-09-26
NO20084517L (no)	2009-01-13
US7557244B2 (en)	2009-07-07
WO2007124394A1 (en)	2007-11-01
KR20090024679A (ko)	2009-03-09
MA30475B1 (fr)	2009-06-01
CR10451A (es)	2009-03-31
TNSN08413A1 (en)	2010-04-14
TWI399362B (zh)	2013-06-21
CY1109399T1 (el)	2014-07-02
CN101687758B (zh)	2014-05-14
EP2021314B1 (en)	2013-01-23
AP2008004656A0 (en)	2008-10-31
EP1849762A1 (en)	2007-10-31
CA2650006C (en)	2016-08-23
SMP200800061B (it)	2009-07-14
PT1849762E (pt)	2009-09-16
EA200802172A1 (ru)	2009-06-30
CR10375A (es)	2009-02-26
IL194790A0 (en)	2009-08-03
AR060568A1 (es)	2008-06-25
BRPI0710656A2 (pt)	2011-08-16
MX2008013445A (es)	2009-03-10
EA016129B9 (ru)	2012-06-29
EA016129B1 (ru)	2012-02-28
JP5479088B2 (ja)	2014-04-23
JP2009544573A (ja)	2009-12-17
CN101687758A (zh)	2010-03-31
PL1849762T3 (pl)	2009-12-31
SI1849762T1 (sl)	2009-12-31
TW200815320A (en)	2008-04-01
ZA200809856B (en)	2009-06-24
ES2400530T3 (es)	2013-04-10
NZ573000A (en)	2011-11-25

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