AP2008004656A0 - Substituted biphenyl carboxylic acids and derivatives thereof - Google Patents

Substituted biphenyl carboxylic acids and derivatives thereof

Info

Publication number: AP2008004656A0
Authority: AP; ARIPO
Prior art keywords: derivatives; carboxylic acids; substituted biphenyl; biphenyl carboxylic; substituted
Prior art date: 2006-04-21

Application number

AP2008004656A

Other languages

English (en)

Inventor

Jess Taylor

Francis Wilson

Yan Zhang

Original Assignee

Cellzome Ltd

Orthomcneil Pharmaceutical Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-21

Filing date

2007-04-20

Publication date

2008-10-31

2007-04-20 Application filed by Cellzome Ltd, Orthomcneil Pharmaceutical Inc filed Critical Cellzome Ltd

2008-10-31 Publication of AP2008004656A0 publication Critical patent/AP2008004656A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AP2008004656A 2006-04-21 2007-04-20 Substituted biphenyl carboxylic acids and derivatives thereof AP2008004656A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP06112938A EP1849762B1 (en)	2006-04-21	2006-04-21	Substituted biphenyl carboxylic acids and derivatives thereof
PCT/US2007/067039 WO2007124394A1 (en)	2006-04-21	2007-04-20	Substituted biphenyl carboxylic acids and derivatives thereof

Publications (1)

Publication Number	Publication Date
AP2008004656A0 true AP2008004656A0 (en)	2008-10-31

Family

ID=36688012

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2008004656A AP2008004656A0 (en)	2006-04-21	2007-04-20	Substituted biphenyl carboxylic acids and derivatives thereof

Country Status (35)

Country	Link
US (1)	US7557244B2 (xx)
EP (2)	EP1849762B1 (xx)
JP (1)	JP5479088B2 (xx)
KR (1)	KR101542255B1 (xx)
CN (1)	CN101687758B (xx)
AP (1)	AP2008004656A0 (xx)
AR (1)	AR060568A1 (xx)
AU (1)	AU2007240335B2 (xx)
BR (1)	BRPI0710656A2 (xx)
CA (1)	CA2650006C (xx)
CR (2)	CR10375A (xx)
CY (1)	CY1109399T1 (xx)
DE (1)	DE602006007810D1 (xx)
DK (1)	DK1849762T3 (xx)
EA (1)	EA016129B9 (xx)
ES (2)	ES2328616T3 (xx)
GE (1)	GEP20115269B (xx)
GT (1)	GT200900120A (xx)
IL (2)	IL194852A0 (xx)
MA (1)	MA30475B1 (xx)
MX (1)	MX2008013445A (xx)
MY (1)	MY148953A (xx)
NO (1)	NO20084517L (xx)
NZ (1)	NZ573000A (xx)
PE (1)	PE20080364A1 (xx)
PL (1)	PL1849762T3 (xx)
PT (1)	PT1849762E (xx)
SI (1)	SI1849762T1 (xx)
SM (1)	SMP200800061B (xx)
TN (1)	TNSN08413A1 (xx)
TW (1)	TWI399362B (xx)
UA (1)	UA95952C2 (xx)
UY (1)	UY30301A1 (xx)
WO (1)	WO2007124394A1 (xx)
ZA (1)	ZA200809856B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2212277B1 (en)	2007-10-19	2016-08-31	Janssen Pharmaceutica, N.V.	Amine linked modulators of y-secretase
JP5439381B2 (ja)	2007-10-19	2014-03-12	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	γ−セクレターゼのピペリジニル及びピペラジニル調節物質
ES2401833T3 (es)	2007-10-19	2013-04-24	Janssen Pharmaceutica, N.V.	Moduladores enlazados de carbono de y-secretasa
US20090306392A1 (en) *	2007-10-19	2009-12-10	Chih Yung Ho	Gsm intermediates
US20110092554A1 (en) *	2007-11-19	2011-04-21	Richard Chesworth	1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders
EP2234954B1 (en)	2007-12-20	2015-02-18	Envivo Pharmaceuticals, Inc.	Tetrasubstituted benzenes
EP2488031A4 (en)	2009-10-16	2014-07-23	Merck Sharp & Dohme	DIARYL ETHER DERIVATIVES AS A NOTCH-PROOFING GAMMETRETASE INHIBITOR
US8785481B2 (en)	2010-09-29	2014-07-22	Merck Sharp & Dohme Corp.	Ether benzotriazole derivatives
WO2012119035A1 (en) *	2011-03-03	2012-09-07	Treventis Corporation	Anti-amyloid compounds and methods
WO2015109109A1 (en)	2014-01-15	2015-07-23	Forum Pharmaceuticals Inc.	Fused morpholinopyrimidines and methods of use thereof
WO2016201168A1 (en)	2015-06-10	2016-12-15	Forum Pharmceuticals Inc.	Oxadiazine compounds and methods of use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5877399A (en) *	1994-01-27	1999-03-02	Johns Hopkins University	Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
JP3802581B2 (ja) *	1995-03-01	2006-07-26	富山化学工業株式会社	新規なビフェニル誘導体またはその塩およびそれらを含有する抗炎症剤
AU5702201A (en) *	2000-04-13	2001-10-30	Mayo Foundation	Abeta<sub>42</sub> lowering agents
DE10131899A1 (de)	2001-07-04	2003-02-27	Boehringer Ingelheim Pharma	In vitro-Screening-Assay für gamma-Secretase
MXPA04012783A (es) *	2002-06-27	2005-02-24	Fujisawa Pharmaceutical Co	Derivados de aminoalcohol.
GB0305918D0 (en) *	2003-03-14	2003-04-23	Glaxo Group Ltd	Novel compounds
WO2005110963A1 (en) *	2004-05-19	2005-11-24	Cellzome Ag	(biphenyl-3-yl)-carboxylic acids and derivatives thereof and their use in therapy
GB0416508D0 (en) *	2004-07-23	2004-08-25	Merck Sharp & Dohme	Therapeutic agents
TW200621227A (en) *	2004-08-24	2006-07-01	Kissei Pharmaceutical	Medicament for preventing or treating fatty liver
EP1937632A1 (en) *	2005-10-06	2008-07-02	Astra Zeneca AB	Novel compounds

2006
- 2006-04-21 DK DK06112938T patent/DK1849762T3/da active
- 2006-04-21 EP EP06112938A patent/EP1849762B1/en not_active Not-in-force
- 2006-04-21 PL PL06112938T patent/PL1849762T3/pl unknown
- 2006-04-21 SI SI200630391T patent/SI1849762T1/sl unknown
- 2006-04-21 DE DE602006007810T patent/DE602006007810D1/de active Active
- 2006-04-21 PT PT06112938T patent/PT1849762E/pt unknown
- 2006-04-21 ES ES06112938T patent/ES2328616T3/es active Active
2007
- 2007-04-20 CN CN200780018586.2A patent/CN101687758B/zh not_active Expired - Fee Related
- 2007-04-20 AP AP2008004656A patent/AP2008004656A0/xx unknown
- 2007-04-20 MY MYPI20084201A patent/MY148953A/en unknown
- 2007-04-20 UA UAA200813476A patent/UA95952C2/ru unknown
- 2007-04-20 WO PCT/US2007/067039 patent/WO2007124394A1/en active Application Filing
- 2007-04-20 UY UY30301A patent/UY30301A1/es unknown
- 2007-04-20 AU AU2007240335A patent/AU2007240335B2/en not_active Ceased
- 2007-04-20 KR KR1020087028566A patent/KR101542255B1/ko not_active IP Right Cessation
- 2007-04-20 EA EA200802172A patent/EA016129B9/ru not_active IP Right Cessation
- 2007-04-20 PE PE2007000496A patent/PE20080364A1/es active IP Right Grant
- 2007-04-20 US US11/737,938 patent/US7557244B2/en not_active Expired - Fee Related
- 2007-04-20 ES ES07760976T patent/ES2400530T3/es active Active
- 2007-04-20 BR BRPI0710656-4A patent/BRPI0710656A2/pt not_active IP Right Cessation
- 2007-04-20 CA CA2650006A patent/CA2650006C/en not_active Expired - Fee Related
- 2007-04-20 GE GEAP200710983A patent/GEP20115269B/en unknown
- 2007-04-20 EP EP07760976A patent/EP2021314B1/en active Active
- 2007-04-20 AR ARP070101725A patent/AR060568A1/es not_active Application Discontinuation
- 2007-04-20 NZ NZ573000A patent/NZ573000A/en not_active IP Right Cessation
- 2007-04-20 TW TW096114160A patent/TWI399362B/zh not_active IP Right Cessation
- 2007-04-20 MX MX2008013445A patent/MX2008013445A/es active IP Right Grant
- 2007-04-20 SM SM200800061T patent/SMP200800061B/it unknown
- 2007-04-20 JP JP2009506782A patent/JP5479088B2/ja not_active Expired - Fee Related
2008
- 2008-10-17 TN TNP2008000413A patent/TNSN08413A1/en unknown
- 2008-10-17 CR CR10375A patent/CR10375A/es not_active Application Discontinuation
- 2008-10-22 IL IL194852A patent/IL194852A0/en unknown
- 2008-10-22 IL IL194790A patent/IL194790A/en not_active IP Right Cessation
- 2008-10-27 NO NO20084517A patent/NO20084517L/no not_active Application Discontinuation
- 2008-11-19 ZA ZA200809856A patent/ZA200809856B/xx unknown
- 2008-11-20 MA MA31395A patent/MA30475B1/fr unknown
- 2008-11-21 CR CR10451A patent/CR10451A/es not_active Application Discontinuation
2009
- 2009-05-11 GT GT200900120A patent/GT200900120A/es unknown
- 2009-09-21 CY CY20091100982T patent/CY1109399T1/el unknown

Also Published As

Publication number	Publication date
EP1849762B1 (en)	2009-07-15
ES2400530T3 (es)	2013-04-10
EP2021314B1 (en)	2013-01-23
SMAP200800061A (it)	2008-11-19
EA016129B1 (ru)	2012-02-28
SI1849762T1 (sl)	2009-12-31
KR101542255B1 (ko)	2015-08-06
AU2007240335A1 (en)	2007-11-01
SMP200800061B (it)	2009-07-14
US20070293567A1 (en)	2007-12-20
KR20090024679A (ko)	2009-03-09
TWI399362B (zh)	2013-06-21
CR10375A (es)	2009-02-26
GEP20115269B (en)	2011-08-25
UA95952C2 (ru)	2011-09-26
PT1849762E (pt)	2009-09-16
CA2650006A1 (en)	2007-11-01
AR060568A1 (es)	2008-06-25
DK1849762T3 (da)	2009-10-12
TNSN08413A1 (en)	2010-04-14
IL194852A0 (en)	2009-08-03
NZ573000A (en)	2011-11-25
EP2021314A1 (en)	2009-02-11
MY148953A (en)	2013-06-14
IL194790A0 (en)	2009-08-03
EA016129B9 (ru)	2012-06-29
PL1849762T3 (pl)	2009-12-31
PE20080364A1 (es)	2008-05-16
JP2009544573A (ja)	2009-12-17
EA200802172A1 (ru)	2009-06-30
WO2007124394A1 (en)	2007-11-01
JP5479088B2 (ja)	2014-04-23
CY1109399T1 (el)	2014-07-02
MX2008013445A (es)	2009-03-10
UY30301A1 (es)	2007-08-31
CR10451A (es)	2009-03-31
CA2650006C (en)	2016-08-23
AU2007240335B2 (en)	2013-05-02
TW200815320A (en)	2008-04-01
ZA200809856B (en)	2009-06-24
GT200900120A (es)	2009-11-16
CN101687758B (zh)	2014-05-14
EP1849762A1 (en)	2007-10-31
BRPI0710656A2 (pt)	2011-08-16
DE602006007810D1 (de)	2009-08-27
CN101687758A (zh)	2010-03-31
MA30475B1 (fr)	2009-06-01
IL194790A (en)	2012-12-31
NO20084517L (no)	2009-01-13
US7557244B2 (en)	2009-07-07
ES2328616T3 (es)	2009-11-16

Publication	Publication Date	Title
ZA200809856B (en)	2009-06-24	Substituted biphenyl carboxylic acids and derivatives thereof
AP2007003978A0 (en)	2007-06-30	(Biphenyl) carboxylic acids and derivatives thereof
IL198970A0 (en)	2010-02-17	Carboxylic acid derivatives
ZA200907414B (en)	2010-06-30	Substituted Benzoylamino-indan-2-carboxylic acids and related compounds
IL183288A0 (en)	2007-09-20	Biaryloxymethylarene carboxylic acids
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HK1155168A1 (en)	2012-05-11	Oxo-heterocyclic substituted carboxylic acid derivates and the use thereof
IL182103A0 (en)	2007-07-24	Benzimidazole acetic acids exhibiting
ZA200807048B (en)	2009-07-29	Branched carboxylic acid diesters
EP2307422A4 (en)	2012-06-20	NEW SPIROCHROMANONE CARBOXYLIC ACIDS
ZA200805006B (en)	2010-10-27	1,3-Dioxane carboxylic acids
IL192846A0 (en)	2009-02-11	Anthranilamide/2-amino-heteroarene carboxamide derivatives
NO20084762L (no)	2009-01-06	Process for the preparation of carboxylic acids and/or derivates thereof
EP2080751A4 (en)	2011-06-22	CARBOXYLIC ACID DERIVATIVE
ZA200800348B (en)	2009-01-28	Derivatives of seleno-amino acids
ZA201003432B (en)	2012-07-25	Biphenyl carboxylic acids and derivatives thereof
EP1973874A4 (en)	2012-04-25	HYDROXYLIC ACIDS WITH LOW PROTONATION CONSTANT
ZA200710874B (en)	2009-02-25	Thiazole carboxylic acid anilides
EP1998763A4 (en)	2010-03-03	USES OF DIPHENYLCARBOXYLIC ACIDS AND CARBOXYLIC ACIDS WITH DIPHENYLAMINE FUNCTION
ZA200703258B (en)	2009-04-29	(Biphenyl) carboxylic acids and derivatives thereof
HK1115579A1 (en)	2008-12-05	(biphenyl) carboxylic acids and derivatives thereof ()
GB0605195D0 (en)	2006-04-26	Starbon acids
ZA200704358B (en)	2008-09-25	Biaryloxymethylarene carboxylic acids
AP2006003847A0 (en)	2006-12-31	Benzhimidazolone carboxylic acid derivatives