DK164476A - Fremgangsmade til fremstilling af piperazinylpyrazinforbindelser - Google Patents

Fremgangsmade til fremstilling af piperazinylpyrazinforbindelser

Info

Publication number: DK164476A
Authority: DK; Denmark
Prior art keywords: preparing; procedure; piperazinylpyrazine; compounds; piperazinylpyrazine compounds
Prior art date: 1975-04-21

Application number

DK164476A

Other languages

English (en)

Other versions

DK143899B (da

DK143899C (da

Inventor

W S Saari

W C Lumma Jr

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-04-21

Filing date

1976-04-07

Publication date

1976-10-22

1976-04-07 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1976-10-22 Publication of DK164476A publication Critical patent/DK164476A/da

1981-10-26 Publication of DK143899B publication Critical patent/DK143899B/da

1982-04-13 Application granted granted Critical

1982-04-13 Publication of DK143899C publication Critical patent/DK143899C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Child & Adolescent Psychology (AREA)
Hematology (AREA)
Obesity (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK164476A 1975-04-21 1976-04-07 Analogifremgangsmaade til fremstilling af piperazinylpyrazinderivater DK143899C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US57005275A	1975-04-21	1975-04-21
US57005275		1975-04-21

Publications (3)

Publication Number	Publication Date
DK164476A true DK164476A (da)	1976-10-22
DK143899B DK143899B (da)	1981-10-26
DK143899C DK143899C (da)	1982-04-13

Family

ID=24277994

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK164476A DK143899C (da)	1975-04-21	1976-04-07	Analogifremgangsmaade til fremstilling af piperazinylpyrazinderivater

Country Status (36)

Country	Link
JP (1)	JPS51136688A (da)
AR (1)	AR210349A1 (da)
AT (1)	AT353795B (da)
AU (1)	AU496854B2 (da)
BE (1)	BE840904A (da)
BG (1)	BG34185A3 (da)
CA (1)	CA1059128A (da)
CH (1)	CH619462A5 (da)
CS (1)	CS195726B2 (da)
CY (1)	CY1090A (da)
DD (1)	DD124599A5 (da)
DE (1)	DE2617205C3 (da)
DK (1)	DK143899C (da)
EG (1)	EG12387A (da)
ES (4)	ES447150A1 (da)
FI (1)	FI62666C (da)
FR (1)	FR2308367A1 (da)
GB (1)	GB1492528A (da)
GR (1)	GR59900B (da)
HK (1)	HK60380A (da)
HU (1)	HU172684B (da)
IE (1)	IE42979B1 (da)
IL (1)	IL49391A (da)
KE (1)	KE3088A (da)
LU (1)	LU74795A1 (da)
MY (1)	MY8100225A (da)
NL (1)	NL167692C (da)
NO (1)	NO146599C (da)
PH (1)	PH12274A (da)
PL (1)	PL99664B1 (da)
PT (1)	PT65027B (da)
RO (1)	RO73278A (da)
SE (1)	SE421695B (da)
SU (1)	SU638260A3 (da)
YU (1)	YU100676A (da)
ZA (1)	ZA762320B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4091098A (en) *	1977-04-25	1978-05-23	Merck & Co., Inc.	3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4163849A (en)	1978-03-17	1979-08-07	Merck & Co., Inc.	Piperazinylpyrazines
US4252816A (en) *	1979-12-03	1981-02-24	Merck & Co., Inc.	Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents
US4339579A (en)	1980-12-29	1982-07-13	American Home Products Corporation	2,6-Bis-(pyrrolopyrazinyl)pyrazines
EP0094498A3 (en) *	1982-05-06	1985-04-03	American Cyanamid Company	Antiatherosclerotic 1-piperazine derivatives
US4547505A (en) *	1983-03-25	1985-10-15	Degussa Aktiengesellschaft	N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
US4788290A (en) *	1987-12-11	1988-11-29	American Home Products Corporation	Serotonergic pyrazine derivatives
EP0580465A1 (fr) *	1992-06-25	1994-01-26	Sanofi	Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés
EP1491532B1 (en)	1997-10-27	2010-12-15	NeuroSearch A/S	Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetyloholine receptors
EP1175416B1 (en)	1999-04-26	2003-07-16	Neurosearch A/S	Heteroaryl diazacycloalkanes, their preparation and use
CA2398937A1 (en) *	2000-02-16	2001-08-23	Neurogen Corporation	Substituted arylpyrazines
US6825198B2 (en) *	2001-06-21	2004-11-30	Pfizer Inc	5-HT receptor ligands and uses thereof
MXPA05000784A (es)	2002-07-19	2005-06-17	Biovitrum Ab	Derivados de piperazinil-pirazinona novedosos para el tratamiento de los trastornos relacionados con el receptor 5-ht2a.
SE0202287D0 (sv) *	2002-07-19	2002-07-19	Biovitrum Ab	New compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2606906A (en) *	1948-10-14	1952-08-12	American Cyanamid Co	1-(2-pyridyl) piperazine and process of preparing same

1976
- 1976-04-07 DK DK164476A patent/DK143899C/da not_active IP Right Cessation
- 1976-04-07 EG EG76205A patent/EG12387A/xx active
- 1976-04-07 SE SE7604093A patent/SE421695B/xx not_active IP Right Cessation
- 1976-04-08 NO NO761207A patent/NO146599C/no unknown
- 1976-04-09 NL NL7603800A patent/NL167692C/xx not_active IP Right Cessation
- 1976-04-09 FI FI760978A patent/FI62666C/fi not_active IP Right Cessation
- 1976-04-12 IL IL49391A patent/IL49391A/xx unknown
- 1976-04-13 PH PH18329A patent/PH12274A/en unknown
- 1976-04-13 GR GR50538A patent/GR59900B/el unknown
- 1976-04-13 AU AU12966/76A patent/AU496854B2/en not_active Expired
- 1976-04-14 CA CA250,732A patent/CA1059128A/en not_active Expired
- 1976-04-14 FR FR7610958A patent/FR2308367A1/fr active Granted
- 1976-04-15 CY CY1090A patent/CY1090A/xx unknown
- 1976-04-15 GB GB15644/76A patent/GB1492528A/en not_active Expired
- 1976-04-15 DD DD192399A patent/DD124599A5/xx unknown
- 1976-04-16 CS CS762549A patent/CS195726B2/cs unknown
- 1976-04-19 ES ES447150A patent/ES447150A1/es not_active Expired
- 1976-04-19 JP JP51043763A patent/JPS51136688A/ja active Granted
- 1976-04-20 CH CH492676A patent/CH619462A5/de not_active IP Right Cessation
- 1976-04-20 DE DE2617205A patent/DE2617205C3/de not_active Expired
- 1976-04-20 SU SU762346054A patent/SU638260A3/ru active
- 1976-04-20 PL PL1976188912A patent/PL99664B1/pl unknown
- 1976-04-20 BE BE166282A patent/BE840904A/xx not_active IP Right Cessation
- 1976-04-20 YU YU01006/76A patent/YU100676A/xx unknown
- 1976-04-20 AT AT288376A patent/AT353795B/de not_active IP Right Cessation
- 1976-04-20 ZA ZA762320A patent/ZA762320B/xx unknown
- 1976-04-20 LU LU74795A patent/LU74795A1/xx unknown
- 1976-04-20 BG BG032968A patent/BG34185A3/xx unknown
- 1976-04-20 AR AR262930A patent/AR210349A1/es active
- 1976-04-20 RO RO7685688A patent/RO73278A/ro unknown
- 1976-04-21 HU HU76ME00001967A patent/HU172684B/hu unknown
- 1976-04-21 PT PT65027A patent/PT65027B/pt unknown
- 1976-04-21 IE IE828/76A patent/IE42979B1/en unknown
1977
- 1977-06-01 ES ES459407A patent/ES459407A1/es not_active Expired
- 1977-06-01 ES ES459406A patent/ES459406A1/es not_active Expired
- 1977-06-01 ES ES459405A patent/ES459405A1/es not_active Expired
1980
- 1980-10-02 KE KE3088A patent/KE3088A/xx unknown
- 1980-10-30 HK HK603/80A patent/HK60380A/xx unknown
1981
- 1981-12-30 MY MY225/81A patent/MY8100225A/xx unknown

Also Published As

Publication number	Publication date
AU1296676A (en)	1977-10-20
ATA288376A (de)	1979-05-15
CS195726B2 (en)	1980-02-29
NO146599B (no)	1982-07-26
DE2617205B2 (de)	1980-05-08
IL49391A0 (en)	1976-06-30
DK143899B (da)	1981-10-26
IE42979L (en)	1976-10-21
PL99664B1 (pl)	1978-07-31
GB1492528A (en)	1977-11-23
NL167692B (nl)	1981-08-17
SE421695B (sv)	1982-01-25
NO761207L (da)	1976-10-22
IE42979B1 (en)	1980-11-19
MY8100225A (en)	1981-12-31
ES459406A1 (es)	1978-08-16
AT353795B (de)	1979-12-10
KE3088A (en)	1980-11-07
HK60380A (en)	1980-11-07
ES459407A1 (es)	1978-08-16
ES447150A1 (es)	1977-09-16
NL167692C (nl)	1982-01-18
IL49391A (en)	1979-09-30
FR2308367B1 (da)	1979-09-21
SE7604093L (sv)	1976-10-22
CA1059128A (en)	1979-07-24
RO73278A (ro)	1982-09-09
CY1090A (en)	1980-12-27
FI62666C (fi)	1983-02-10
ES459405A1 (es)	1978-08-16
DD124599A5 (da)	1977-03-02
JPS5522475B2 (da)	1980-06-17
NO146599C (no)	1982-11-03
EG12387A (en)	1978-12-31
SU638260A3 (ru)	1978-12-15
DE2617205C3 (de)	1981-01-29
FI760978A (da)	1976-10-22
JPS51136688A (en)	1976-11-26
CH619462A5 (en)	1980-09-30
HU172684B (hu)	1978-11-28
PH12274A (en)	1978-12-12
PT65027B (en)	1978-04-03
DE2617205A1 (de)	1976-10-28
ZA762320B (en)	1977-11-30
LU74795A1 (da)	1977-02-07
BG34185A3 (en)	1983-07-15
FI62666B (fi)	1982-10-29
YU100676A (en)	1982-08-31
FR2308367A1 (fr)	1976-11-19
NL7603800A (nl)	1976-10-25
BE840904A (fr)	1976-08-16
AR210349A1 (es)	1977-07-29
PT65027A (en)	1976-05-01
GR59900B (en)	1978-03-16
AU496854B2 (en)	1978-11-02
DK143899C (da)	1982-04-13

Publication	Publication Date	Title
DK143706C (da)	1982-03-15	Fremgangsmaade til fremstilling af svovlholdige organosiliciumforbindelser
DK494876A (da)	1977-05-08	Fremgangsmade til fremstilling af piperidinderivater
DK484576A (da)	1977-04-29	Fremgangsmade til fremstilling af 2-aroyl-3-phenyl-benzothiophenforbindelser
DK562376A (da)	1977-06-24	Fremgangsmade til fremstilling af ergolinderivater
DK442476A (da)	1977-04-03	Fremgangsmade til fremstilling af pyrimidinforbindelser
DK462376A (da)	1977-04-17	Fremgangsmade til fremstilling af 5-halogenpyrimidinderivater
DK87876A (da)	1976-09-04	Fremgangsmade til fremstilling af n-acyl-l-metionin
DK243176A (da)	1976-12-04	Fremgangsmade til fremstilling af polycliske forbindelser
DK517776A (da)	1977-05-19	Fremgangsmade til femstilling af heterocycliske forbindelser
DK415676A (da)	1977-04-09	Fremgangsmade til fremstilling af pilocarpiniumsalte
DK243676A (da)	1976-12-03	Fremgangsmade til fremstilling af pyrrolforbindelser
DK272676A (da)	1976-12-20	Fremgangsmade til fremstilling af cephalosporinforbindelser
DK164476A (da)	1976-10-22	Fremgangsmade til fremstilling af piperazinylpyrazinforbindelser
DK215676A (da)	1976-11-16	Fremgangsmade til fremstilling af rifamycinforbindelser
DK324776A (da)	1977-01-29	Fremgangsmade til fremstilling af 3-cyanoimino-3-aminopropionitriler
DK372576A (da)	1977-03-03	Fremgangsmade til fremstilling af polyaminforbindelser
DK566977A (da)	1978-06-21	Fremgangsmaade til fremstilling af polyenforbindelser
DK305876A (da)	1977-01-09	Fremgangsmade til fremstilling af l-pyroglutamyl-l-prolinamid
DK155598C (da)	1989-09-25	Fremgangsmaade til fremstilling af ethylchlorthioformiat
DK220276A (da)	1976-11-21	Fremgangsmade til fremstilling af rifamycinforbindelser
DK247877A (da)	1977-12-05	Fremgangsmade til fremstilling af klavamforbindelser
DK283476A (da)	1976-12-28	Fremgangsmade til fremstilling af beta-acylpyrroler
DK143281C (da)	1981-12-07	Fremgangsmaade til fremstilling af phosphitchlorider
DK143137C (da)	1981-11-09	Fremgangsmaade til fremstilling af phosphitchlorider
DK511376A (da)	1977-05-14	Fremgangsmade til fremstilling af imidazolforbindelser

Legal Events

Date	Code	Title	Description
1988-12-19	PBP	Patent lapsed