FR2308367B1 - - Google Patents

Info

Publication number: FR2308367B1
Authority: FR; France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR7610958A

Other languages

Other versions

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck and Co Inc

Original Assignee

Merck and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-04-21

Filing date

1976-04-14

Publication date

1979-09-21

1976-04-14 Application filed by Merck and Co Inc filed Critical Merck and Co Inc

1976-11-19 Publication of FR2308367A1 publication Critical patent/FR2308367A1/fr

1979-09-21 Application granted granted Critical

1979-09-21 Publication of FR2308367B1 publication Critical patent/FR2308367B1/fr

Status Granted legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Child & Adolescent Psychology (AREA)
Hematology (AREA)
Obesity (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FR7610958A 1975-04-21 1976-04-14 Piperazinyl pyrazines Granted FR2308367A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US57005275A	1975-04-21	1975-04-21

Publications (2)

Publication Number	Publication Date
FR2308367A1 FR2308367A1 (fr)	1976-11-19
FR2308367B1 true FR2308367B1 (da)	1979-09-21

Family

ID=24277994

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7610958A Granted FR2308367A1 (fr)	1975-04-21	1976-04-14	Piperazinyl pyrazines

Country Status (36)

Country	Link
JP (1)	JPS51136688A (da)
AR (1)	AR210349A1 (da)
AT (1)	AT353795B (da)
AU (1)	AU496854B2 (da)
BE (1)	BE840904A (da)
BG (1)	BG34185A3 (da)
CA (1)	CA1059128A (da)
CH (1)	CH619462A5 (da)
CS (1)	CS195726B2 (da)
CY (1)	CY1090A (da)
DD (1)	DD124599A5 (da)
DE (1)	DE2617205C3 (da)
DK (1)	DK143899C (da)
EG (1)	EG12387A (da)
ES (4)	ES447150A1 (da)
FI (1)	FI62666C (da)
FR (1)	FR2308367A1 (da)
GB (1)	GB1492528A (da)
GR (1)	GR59900B (da)
HK (1)	HK60380A (da)
HU (1)	HU172684B (da)
IE (1)	IE42979B1 (da)
IL (1)	IL49391A (da)
KE (1)	KE3088A (da)
LU (1)	LU74795A1 (da)
MY (1)	MY8100225A (da)
NL (1)	NL167692C (da)
NO (1)	NO146599C (da)
PH (1)	PH12274A (da)
PL (1)	PL99664B1 (da)
PT (1)	PT65027B (da)
RO (1)	RO73278A (da)
SE (1)	SE421695B (da)
SU (1)	SU638260A3 (da)
YU (1)	YU100676A (da)
ZA (1)	ZA762320B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4091098A (en) *	1977-04-25	1978-05-23	Merck & Co., Inc.	3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4163849A (en)	1978-03-17	1979-08-07	Merck & Co., Inc.	Piperazinylpyrazines
US4252816A (en) *	1979-12-03	1981-02-24	Merck & Co., Inc.	Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents
US4339579A (en)	1980-12-29	1982-07-13	American Home Products Corporation	2,6-Bis-(pyrrolopyrazinyl)pyrazines
EP0094498A3 (en) *	1982-05-06	1985-04-03	American Cyanamid Company	Antiatherosclerotic 1-piperazine derivatives
US4547505A (en) *	1983-03-25	1985-10-15	Degussa Aktiengesellschaft	N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
US4788290A (en) *	1987-12-11	1988-11-29	American Home Products Corporation	Serotonergic pyrazine derivatives
EP0580465A1 (fr) *	1992-06-25	1994-01-26	Sanofi	Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés
EP1491532B1 (en)	1997-10-27	2010-12-15	NeuroSearch A/S	Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetyloholine receptors
EP1175416B1 (en)	1999-04-26	2003-07-16	Neurosearch A/S	Heteroaryl diazacycloalkanes, their preparation and use
CA2398937A1 (en) *	2000-02-16	2001-08-23	Neurogen Corporation	Substituted arylpyrazines
US6825198B2 (en) *	2001-06-21	2004-11-30	Pfizer Inc	5-HT receptor ligands and uses thereof
MXPA05000784A (es)	2002-07-19	2005-06-17	Biovitrum Ab	Derivados de piperazinil-pirazinona novedosos para el tratamiento de los trastornos relacionados con el receptor 5-ht2a.
SE0202287D0 (sv) *	2002-07-19	2002-07-19	Biovitrum Ab	New compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2606906A (en) *	1948-10-14	1952-08-12	American Cyanamid Co	1-(2-pyridyl) piperazine and process of preparing same

1976
- 1976-04-07 DK DK164476A patent/DK143899C/da not_active IP Right Cessation
- 1976-04-07 EG EG76205A patent/EG12387A/xx active
- 1976-04-07 SE SE7604093A patent/SE421695B/xx not_active IP Right Cessation
- 1976-04-08 NO NO761207A patent/NO146599C/no unknown
- 1976-04-09 NL NL7603800A patent/NL167692C/xx not_active IP Right Cessation
- 1976-04-09 FI FI760978A patent/FI62666C/fi not_active IP Right Cessation
- 1976-04-12 IL IL49391A patent/IL49391A/xx unknown
- 1976-04-13 PH PH18329A patent/PH12274A/en unknown
- 1976-04-13 GR GR50538A patent/GR59900B/el unknown
- 1976-04-13 AU AU12966/76A patent/AU496854B2/en not_active Expired
- 1976-04-14 CA CA250,732A patent/CA1059128A/en not_active Expired
- 1976-04-14 FR FR7610958A patent/FR2308367A1/fr active Granted
- 1976-04-15 CY CY1090A patent/CY1090A/xx unknown
- 1976-04-15 GB GB15644/76A patent/GB1492528A/en not_active Expired
- 1976-04-15 DD DD192399A patent/DD124599A5/xx unknown
- 1976-04-16 CS CS762549A patent/CS195726B2/cs unknown
- 1976-04-19 ES ES447150A patent/ES447150A1/es not_active Expired
- 1976-04-19 JP JP51043763A patent/JPS51136688A/ja active Granted
- 1976-04-20 CH CH492676A patent/CH619462A5/de not_active IP Right Cessation
- 1976-04-20 DE DE2617205A patent/DE2617205C3/de not_active Expired
- 1976-04-20 SU SU762346054A patent/SU638260A3/ru active
- 1976-04-20 PL PL1976188912A patent/PL99664B1/pl unknown
- 1976-04-20 BE BE166282A patent/BE840904A/xx not_active IP Right Cessation
- 1976-04-20 YU YU01006/76A patent/YU100676A/xx unknown
- 1976-04-20 AT AT288376A patent/AT353795B/de not_active IP Right Cessation
- 1976-04-20 ZA ZA762320A patent/ZA762320B/xx unknown
- 1976-04-20 LU LU74795A patent/LU74795A1/xx unknown
- 1976-04-20 BG BG032968A patent/BG34185A3/xx unknown
- 1976-04-20 AR AR262930A patent/AR210349A1/es active
- 1976-04-20 RO RO7685688A patent/RO73278A/ro unknown
- 1976-04-21 HU HU76ME00001967A patent/HU172684B/hu unknown
- 1976-04-21 PT PT65027A patent/PT65027B/pt unknown
- 1976-04-21 IE IE828/76A patent/IE42979B1/en unknown
1977
- 1977-06-01 ES ES459407A patent/ES459407A1/es not_active Expired
- 1977-06-01 ES ES459406A patent/ES459406A1/es not_active Expired
- 1977-06-01 ES ES459405A patent/ES459405A1/es not_active Expired
1980
- 1980-10-02 KE KE3088A patent/KE3088A/xx unknown
- 1980-10-30 HK HK603/80A patent/HK60380A/xx unknown
1981
- 1981-12-30 MY MY225/81A patent/MY8100225A/xx unknown

Also Published As

Publication number	Publication date
AU1296676A (en)	1977-10-20
ATA288376A (de)	1979-05-15
CS195726B2 (en)	1980-02-29
NO146599B (no)	1982-07-26
DE2617205B2 (de)	1980-05-08
IL49391A0 (en)	1976-06-30
DK143899B (da)	1981-10-26
IE42979L (en)	1976-10-21
PL99664B1 (pl)	1978-07-31
GB1492528A (en)	1977-11-23
NL167692B (nl)	1981-08-17
SE421695B (sv)	1982-01-25
NO761207L (da)	1976-10-22
IE42979B1 (en)	1980-11-19
MY8100225A (en)	1981-12-31
ES459406A1 (es)	1978-08-16
AT353795B (de)	1979-12-10
KE3088A (en)	1980-11-07
HK60380A (en)	1980-11-07
ES459407A1 (es)	1978-08-16
ES447150A1 (es)	1977-09-16
NL167692C (nl)	1982-01-18
IL49391A (en)	1979-09-30
SE7604093L (sv)	1976-10-22
CA1059128A (en)	1979-07-24
RO73278A (ro)	1982-09-09
CY1090A (en)	1980-12-27
FI62666C (fi)	1983-02-10
ES459405A1 (es)	1978-08-16
DD124599A5 (da)	1977-03-02
JPS5522475B2 (da)	1980-06-17
NO146599C (no)	1982-11-03
EG12387A (en)	1978-12-31
SU638260A3 (ru)	1978-12-15
DE2617205C3 (de)	1981-01-29
DK164476A (da)	1976-10-22
FI760978A (da)	1976-10-22
JPS51136688A (en)	1976-11-26
CH619462A5 (en)	1980-09-30
HU172684B (hu)	1978-11-28
PH12274A (en)	1978-12-12
PT65027B (en)	1978-04-03
DE2617205A1 (de)	1976-10-28
ZA762320B (en)	1977-11-30
LU74795A1 (da)	1977-02-07
BG34185A3 (en)	1983-07-15
FI62666B (fi)	1982-10-29
YU100676A (en)	1982-08-31
FR2308367A1 (fr)	1976-11-19
NL7603800A (nl)	1976-10-25
BE840904A (fr)	1976-08-16
AR210349A1 (es)	1977-07-29
PT65027A (en)	1976-05-01
GR59900B (en)	1978-03-16
AU496854B2 (en)	1978-11-02
DK143899C (da)	1982-04-13

Publication	Publication Date	Title
JPS51132591U (da)	1976-10-25
DD124599A5 (da)	1977-03-02
BG21783A1 (da)	1976-09-20
BG22224A1 (da)	1977-02-20
BG22231A1 (da)	1977-02-20
BG22590A1 (da)	1977-04-20
BG22729A1 (da)	1977-04-20
BG23074A1 (da)	1977-07-12
CH1354675A4 (da)	1977-05-13
CH305975A4 (da)	1977-08-15
CH581501A5 (da)	1976-11-15
CH585477A5 (da)	1977-02-28
CH589972A5 (da)	1977-07-29
CH590358A5 (da)	1977-08-15
CH590504B5 (da)	1977-08-15
CH591776A5 (da)	1977-09-30
CH592315A5 (da)	1977-10-31
CH592437A5 (da)	1977-10-31
CH592755A5 (da)	1977-11-15
CH592898A5 (da)	1977-11-15
CH592935A5 (da)	1977-11-15
CH593797A5 (da)	1977-12-15
CH594296A5 (da)	1978-01-13
CH594339A5 (da)	1978-01-13
CH594510A5 (da)	1978-01-13

Legal Events

Date	Code	Title	Description
1994-02-25	ST	Notification of lapse