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DK1165791T3 - Humant cytokin som zalpha-receptor-ligand og anvendelse deraf - Google Patents

Humant cytokin som zalpha-receptor-ligand og anvendelse deraf

Info

Publication number
DK1165791T3
DK1165791T3 DK00916164T DK00916164T DK1165791T3 DK 1165791 T3 DK1165791 T3 DK 1165791T3 DK 00916164 T DK00916164 T DK 00916164T DK 00916164 T DK00916164 T DK 00916164T DK 1165791 T3 DK1165791 T3 DK 1165791T3
Authority
DK
Denmark
Prior art keywords
receptor ligand
human cytokine
polypeptide
zalpha
zalpha receptor
Prior art date
Application number
DK00916164T
Other languages
Danish (da)
English (en)
Inventor
Scott R Presnell
Donald C Foster
Richard D Holly
Janet V Johnston
Julie E Novak
Cindy A Sprecher
Jane A Gross
Andrew J Nelson
Stacey R Dillon
Angela K Hammond
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27385745&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1165791(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of DK1165791T3 publication Critical patent/DK1165791T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK00916164T 1999-03-09 2000-03-09 Humant cytokin som zalpha-receptor-ligand og anvendelse deraf DK1165791T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26490899A 1999-03-09 1999-03-09
US26599299A 1999-03-11 1999-03-11
US14201399P 1999-07-01 1999-07-01
PCT/US2000/006067 WO2000053761A2 (en) 1999-03-09 2000-03-09 Human cytokine as ligand of the zalpha receptor and uses thereof

Publications (1)

Publication Number Publication Date
DK1165791T3 true DK1165791T3 (da) 2008-02-11

Family

ID=27385745

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00916164T DK1165791T3 (da) 1999-03-09 2000-03-09 Humant cytokin som zalpha-receptor-ligand og anvendelse deraf

Country Status (23)

Country Link
EP (3) EP1881070B1 (es)
JP (1) JP4405686B2 (es)
KR (1) KR100743640B1 (es)
CN (5) CN102406937A (es)
AT (1) ATE377076T1 (es)
AU (2) AU777842B2 (es)
BR (1) BR0008772B1 (es)
CA (1) CA2366921C (es)
CZ (1) CZ302921B6 (es)
DE (1) DE60036930T2 (es)
DK (1) DK1165791T3 (es)
ES (1) ES2295019T3 (es)
HU (1) HU229148B1 (es)
IL (5) IL145288A0 (es)
MX (1) MXPA01009074A (es)
NO (2) NO331551B1 (es)
NZ (1) NZ514708A (es)
PL (1) PL207350B1 (es)
PT (1) PT1165791E (es)
RU (1) RU2346951C2 (es)
UA (1) UA84387C2 (es)
WO (1) WO2000053761A2 (es)
ZA (1) ZA017370B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057128A (en) 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
US7189400B2 (en) 1998-03-17 2007-03-13 Genetics Institute, Llc Methods of treatment with antagonists of MU-1
US7198789B2 (en) 1998-03-17 2007-04-03 Genetics Institute, Llc Methods and compositions for modulating interleukin-21 receptor activity
HU229148B1 (en) * 1999-03-09 2013-09-30 Zymogenetics Inc Seattle Human cytokine as ligand of the zalpha receptor and uses thereof
WO2003028630A2 (en) 2001-10-04 2003-04-10 Genetics Institute Llc. Methods and compositions for modulating interleukin-21 receptor activity
ATE444363T1 (de) * 2001-11-05 2009-10-15 Zymogenetics Inc Il-21-antagonisten
PT1531850E (pt) * 2002-06-07 2012-05-07 Zymogenetics Inc Utilização de il-21 e anticorpo monoclonal para tratar cancros sólidos
WO2004007682A2 (en) 2002-07-15 2004-01-22 Wyeth Methods and compositions for modulating t helper (th) cell development and function
AU2003273758A1 (en) * 2002-10-11 2004-05-04 Novo Nordisk A/S Treatment of allergic conditions by use of il 21
EP1782823A3 (en) * 2002-10-11 2007-05-16 Novo Nordisk A/S IL-21 peptides and nucleic acids
ES2334127T3 (es) * 2002-12-13 2010-03-05 Zymogenetics, Inc. Produccion de il-21 en huespedes procariotas.
BRPI0408315A (pt) * 2003-03-14 2006-03-07 Wyeth Corp anticorpo isolado, composição farmacêutica, ácido nucleico isolado, vetor de expressão, célula hospedeira, métodos de produzir um anticorpo, de gerar um anticorpo ou fragmento de ligação de antìgeno, de regular uma resposta imune, de tratar ou prevenir um distúrbio associado com célula imune em um paciente, de tratar ou prevenir um distúrbio hiperproliferativo em um paciente, e, kit de diagnóstico
WO2004112703A2 (en) * 2003-06-19 2004-12-29 Centocor, Inc. Interleukin-21 analogs
WO2005014642A2 (en) 2003-07-21 2005-02-17 Transgene S.A. Novel multifunctional cytokines
DE602004031341D1 (de) 2003-07-21 2011-03-24 Transgene Sa Multifunktionelle cytokine
JP2007506789A (ja) * 2003-09-25 2007-03-22 ザイモジェネティクス， インコーポレイテッド Ｉｌ−２１を用いた自己免疫疾患の治療方法
ATE481420T1 (de) 2003-10-10 2010-10-15 Novo Nordisk As Il-21-derivate
US20060228331A1 (en) * 2003-10-10 2006-10-12 Novo Nordisk A/S IL-21 Derivatives and variants
EP2633866A3 (en) 2003-10-17 2013-12-18 Novo Nordisk A/S Combination therapy
JP2007522109A (ja) * 2004-01-15 2007-08-09 ノボ　ノルディスク　アクティーゼルスカブ 自己免疫疾患の治療およびｉｌ−２１での同種異系移植片拒絶反応
DK2842576T3 (en) 2004-01-21 2017-10-16 Novo Nordisk Healthcare Ag Transglutaminase-mediated peptide conjugation
GT200600148A (es) 2005-04-14 2006-11-22 Metodos para el tratamiento y la prevencion de fibrosis
DE602006020032D1 (de) 2005-04-18 2011-03-24 Novo Nordisk As Il-21-varianten
ES2491118T3 (es) * 2005-11-28 2014-09-05 Zymogenetics, Inc. Antagonistas de IL-21
CN101553501A (zh) 2006-10-26 2009-10-07 诺沃-诺迪斯克有限公司 Il-21变种
EP2109620B1 (en) 2006-12-21 2012-08-22 Novo Nordisk A/S Interleukin-21 variants with altered binding to the il-21 receptor
KR101591316B1 (ko) 2007-12-07 2016-02-05 지모제넥틱스, 인코포레이티드 항-사람 ｉｌ-21 단클론성 항체
AR071885A1 (es) 2008-05-23 2010-07-21 Wyeth Corp Proteinas de union al receptor de interleuquina 21
EP2296689A1 (en) 2008-05-23 2011-03-23 Wyeth LLC Methods of treatment utilizing binding proteins of the interleukin-21 receptor
CA2739357A1 (en) 2008-09-23 2010-04-08 Wyeth Llc Methods for predicting production of activating signals by cross-linked binding proteins
CN102021196B (zh) * 2009-11-20 2013-06-26 上海杰隆生物工程股份有限公司 毕赤酵母生产重组人白细胞介素21的方法
JP6464081B2 (ja) 2012-06-27 2019-02-06 ラトガース，ザ ステート ユニバーシティ オブ ニュー ジャージー フローサイトメトリーを用いたｒｎａ測定によるｔ細胞活性化のための迅速アッセイ
WO2015110930A1 (en) 2014-01-24 2015-07-30 Pfizer Inc. Modified interleukin 21 receptor proteins
EP2982693A1 (en) * 2014-08-07 2016-02-10 Affimed Therapeutics AG CD3 binding domain
US12012441B2 (en) 2020-10-26 2024-06-18 Neptune Biosciences Llc Engineered human IL-21 cytokines and methods for using the same
CN112662694A (zh) * 2020-12-25 2021-04-16 康九生物科技(长春)有限公司 一种麦芽糖结合蛋白、麦芽糖结合蛋白表达载体、重组工程菌及其应用

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE54046B1 (en) 1981-08-25 1989-05-24 Celltech Ltd Expression vectors
US4579821A (en) 1981-11-23 1986-04-01 University Patents, Inc. Control of DNA sequence transcription
US4656134A (en) 1982-01-11 1987-04-07 Board Of Trustees Of Leland Stanford Jr. University Gene amplification in eukaryotic cells
US4486533A (en) 1982-09-02 1984-12-04 St. Louis University Filamentous fungi functional replicating extrachromosomal element
US4599311A (en) 1982-08-13 1986-07-08 Kawasaki Glenn H Glycolytic promotersfor regulated protein expression: protease inhibitor
US4977092A (en) 1985-06-26 1990-12-11 Amgen Expression of exogenous polypeptides and polypeptide products including hepatitis B surface antigen in yeast cells
US4601978A (en) 1982-11-24 1986-07-22 The Regents Of The University Of California Mammalian metallothionein promoter system
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
US5139936A (en) 1983-02-28 1992-08-18 Collaborative Research, Inc. Use of the GAL1 yeast promoter
US4661454A (en) 1983-02-28 1987-04-28 Collaborative Research, Inc. GAL1 yeast promoter linked to non galactokinase gene
US4650764A (en) 1983-04-12 1987-03-17 Wisconsin Alumni Research Foundation Helper cell
US4870008A (en) 1983-08-12 1989-09-26 Chiron Corporation Secretory expression in eukaryotes
US4931373A (en) 1984-05-25 1990-06-05 Zymogenetics, Inc. Stable DNA constructs for expression of α-1 antitrypsin
US4766073A (en) 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4990446A (en) 1984-12-06 1991-02-05 Labofina, S.A. Promoters for the expression of foreign genes in yeast, plasmids comprising them, and use thereof for the production of polypeptides
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GR860984B (en) 1985-04-17 1986-08-18 Zymogenetics Inc Expression of factor vii and ix activities in mammalian cells
US4882279A (en) 1985-10-25 1989-11-21 Phillips Petroleum Company Site selective genomic modification of yeast of the genus pichia
US4935349A (en) 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus
GB8611832D0 (en) 1986-05-15 1986-06-25 Holland I B Polypeptide
US4980289A (en) 1987-04-27 1990-12-25 Wisconsin Alumni Research Foundation Promoter deficient retroviral vector
US5063154A (en) 1987-06-24 1991-11-05 Whitehead Institute For Biomedical Research Pheromone - inducible yeast promoter
US5567584A (en) 1988-01-22 1996-10-22 Zymogenetics, Inc. Methods of using biologically active dimerized polypeptide fusions to detect PDGF
EP0721983A1 (en) 1988-01-22 1996-07-17 ZymoGenetics, Inc. Methods of producing biologically active peptide dimers
US4956288A (en) 1988-04-22 1990-09-11 Biogen, Inc. Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5162228A (en) 1988-12-28 1992-11-10 Takeda Chemical Industries, Ltd. Gylceraldehyde-3-phosphate dehydrogenase gene and promoter
US5124263A (en) 1989-01-12 1992-06-23 Wisconsin Alumni Research Foundation Recombination resistant retroviral helper cell and products produced thereby
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5162222A (en) 1989-07-07 1992-11-10 Guarino Linda A Use of baculovirus early promoters for expression of foreign genes in stably transformed insect cells or recombinant baculoviruses
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
US5298418A (en) 1991-09-16 1994-03-29 Boyce Thompson Institute For Plant Research, Inc. Cell line isolated from larval midgut tissue of Trichoplusia ni
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
CA2144651A1 (en) 1992-09-14 1994-03-31 Timothy J. Miller Immortalized cells and uses therefor
AU7477394A (en) 1993-07-30 1995-03-27 University Of Medicine And Dentistry Of New Jersey Efficient gene transfer into primary lymphocytes
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5795966A (en) * 1995-02-22 1998-08-18 Immunex Corp Antagonists of interleukin-15
EP0889966A1 (en) 1995-11-09 1999-01-13 ZymoGenetics, Inc. Compositions and methods for producing heterologous polypeptides in pichia methanolica
AU718510B2 (en) 1996-07-17 2000-04-13 Zymogenetics Inc. Transformation of pichia methanolica
CA2261020C (en) 1996-07-17 2004-06-08 Zymogenetics, Inc. Preparation of pichia methanolica auxotrophic mutants
CA2616914C (en) 1996-12-03 2012-05-29 Abgenix, Inc. Egfr-binding antibody
IL122818A0 (en) * 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
US6057128A (en) * 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
HU229148B1 (en) * 1999-03-09 2013-09-30 Zymogenetics Inc Seattle Human cytokine as ligand of the zalpha receptor and uses thereof
US9418201B1 (en) 2015-11-19 2016-08-16 International Business Machines Corporation Integration of functional analysis and common path pessimism removal in static timing analysis

Also Published As

Publication number Publication date
EP2295577A2 (en) 2011-03-16
NO20014364D0 (no) 2001-09-07
RU2346951C2 (ru) 2009-02-20
BR0008772B1 (pt) 2011-11-01
EP1165791A2 (en) 2002-01-02
KR100743640B1 (ko) 2007-07-27
IL145288A (en) 2010-11-30
NO331551B1 (no) 2012-01-23
CZ302921B6 (cs) 2012-01-18
ATE377076T1 (de) 2007-11-15
CN101575377A (zh) 2009-11-11
IL195713A (en) 2010-11-30
KR20010103794A (ko) 2001-11-23
MXPA01009074A (es) 2002-03-27
ZA017370B (en) 2002-06-26
EP1881070A3 (en) 2008-03-05
EP1165791B1 (en) 2007-10-31
JP2002537839A (ja) 2002-11-12
RU2004126135A (ru) 2006-02-10
NO20014364L (no) 2001-11-09
CA2366921A1 (en) 2000-09-14
PT1165791E (pt) 2008-01-16
EP1881070B1 (en) 2012-10-03
CN1378595A (zh) 2002-11-06
CN101575377B (zh) 2012-12-26
PL351160A1 (en) 2003-03-24
HU229148B1 (en) 2013-09-30
EP1881070A2 (en) 2008-01-23
NO20111085L (no) 2001-11-09
BR0008772A (pt) 2002-05-07
CN1927883A (zh) 2007-03-14
PL207350B1 (pl) 2010-12-31
ES2295019T3 (es) 2008-04-16
DE60036930T2 (de) 2008-10-09
AU777842B2 (en) 2004-11-04
EP2295577A3 (en) 2012-08-08
JP4405686B2 (ja) 2010-01-27
NZ514708A (en) 2005-01-28
CN100500846C (zh) 2009-06-17
AU3731200A (en) 2000-09-28
DE60036930D1 (de) 2007-12-13
AU2005200240A1 (en) 2005-02-17
CN1827639A (zh) 2006-09-06
CZ20013184A3 (cs) 2002-04-17
HUP0200418A3 (en) 2003-12-29
HUP0200418A2 (hu) 2002-05-29
IL207403A (en) 2012-03-29
UA84387C2 (ru) 2008-10-27
CN1927883B (zh) 2011-09-21
WO2000053761A3 (en) 2000-12-21
CA2366921C (en) 2013-12-17
WO2000053761A2 (en) 2000-09-14
IL207424A (en) 2013-04-30
IL145288A0 (en) 2002-06-30
CN102406937A (zh) 2012-04-11

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