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CA2995870C - Microorganismes pour la production d'acide adipique et autres composes - Google Patents

Microorganismes pour la production d'acide adipique et autres composes Download PDF

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Publication number
CA2995870C
CA2995870C CA2995870A CA2995870A CA2995870C CA 2995870 C CA2995870 C CA 2995870C CA 2995870 A CA2995870 A CA 2995870A CA 2995870 A CA2995870 A CA 2995870A CA 2995870 C CA2995870 C CA 2995870C
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coa
adipate
pathway
caprolactam
microbial organism
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CA2995870A
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CA2995870A1 (fr
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Anthony P. Burgard
Priti Pharkya
Robin E. Osterhout
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Genomatica Inc
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Genomatica Inc
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
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    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
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    • C12P7/00—Preparation of oxygen-containing organic compounds
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
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    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0101—Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01035—3-Hydroxyacyl-CoA dehydrogenase (1.1.1.35)
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    • C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
    • C12Y103/01031—2-Enoate reductase (1.3.1.31)
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    • C12Y206/01—Transaminases (2.6.1)
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    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)

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  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Il est décrit un organisme microbien inorganique ayant une voie dadipate, dacide 6-aminocaproïque ou de caprolactame. Lorganisme microbien contient au moins un acide nucléique exogène qui code pour une enzyme de la voie dadipate, dacide 6-aminocaproïque ou de caprolactame respective. Il est également décrit une méthode de production dadipate, dacide 6-aminocaproïque ou de caprolactame. La méthode peut comprendre la culture dun organisme microbien producteur dadipate, dacide 6-aminocaproïque ou de caprolactame, lequel organisme exprime au moins un acide nucléique exogène qui code pour une concentration suffisante dune enzyme de la voie dadipate dacide 6-aminocaproïque ou de caprolactame pour la production du produit respectif, et ce, dans des conditions qui permettent de produire de ladipate, de lacide 6-aminocaproïque ou du caprolactame et pour une durée suffisante pour produire ces derniers.
CA2995870A 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes Active CA2995870C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3175935A CA3175935A1 (fr) 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4005908P 2008-03-27 2008-03-27
US61/040,059 2008-03-27
CA2719679A CA2719679C (fr) 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes

Related Parent Applications (1)

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CA2719679A Division CA2719679C (fr) 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3175935A Division CA3175935A1 (fr) 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes

Publications (2)

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CA2995870A1 CA2995870A1 (fr) 2009-12-17
CA2995870C true CA2995870C (fr) 2022-11-01

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ID=41400667

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CA3175935A Pending CA3175935A1 (fr) 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes
CA2995870A Active CA2995870C (fr) 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes
CA2719679A Active CA2719679C (fr) 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes

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CA3175935A Pending CA3175935A1 (fr) 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2719679A Active CA2719679C (fr) 2008-03-27 2009-03-27 Microorganismes pour la production d'acide adipique et autres composes

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Country Link
US (11) US7799545B2 (fr)
EP (2) EP3351619A1 (fr)
JP (6) JP5951990B2 (fr)
CN (4) CN106119112B (fr)
BR (1) BRPI0910928A2 (fr)
CA (3) CA3175935A1 (fr)
DK (1) DK2265709T3 (fr)
ES (1) ES2656790T3 (fr)
HU (1) HUE035611T2 (fr)
LT (1) LT2265709T (fr)
NO (1) NO2265709T3 (fr)
PL (1) PL2265709T3 (fr)
SI (1) SI2265709T1 (fr)
WO (1) WO2009151728A2 (fr)

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