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ATE517902T1 - Makrocyclische inhibitoren des hepatitis-c-virus - Google Patents

Makrocyclische inhibitoren des hepatitis-c-virus

Info

Publication number
ATE517902T1
ATE517902T1 AT06764264T AT06764264T ATE517902T1 AT E517902 T1 ATE517902 T1 AT E517902T1 AT 06764264 T AT06764264 T AT 06764264T AT 06764264 T AT06764264 T AT 06764264T AT E517902 T1 ATE517902 T1 AT E517902T1
Authority
AT
Austria
Prior art keywords
hepatitis
virus
macrocyclic inhibitors
macrocyclic
inhibitors
Prior art date
Application number
AT06764264T
Other languages
English (en)
Inventor
Pierre Raboisson
Kock Herman De
Sandrine Vendeville
Lili Hu
De Vreken Wim Van
Gowan David Mc
Abdellah Tahri
Dominique Surleraux
Kenneth Simmen
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37036843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE517902(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Application granted granted Critical
Publication of ATE517902T1 publication Critical patent/ATE517902T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT06764264T 2005-07-29 2006-07-28 Makrocyclische inhibitoren des hepatitis-c-virus ATE517902T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05107067 2005-07-29
EP05107413 2005-08-11
PCT/EP2006/064813 WO2007014919A1 (en) 2005-07-29 2006-07-28 Macrocylic inhibitors of hepatitis c virus

Publications (1)

Publication Number Publication Date
ATE517902T1 true ATE517902T1 (de) 2011-08-15

Family

ID=37036843

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06764264T ATE517902T1 (de) 2005-07-29 2006-07-28 Makrocyclische inhibitoren des hepatitis-c-virus

Country Status (28)

Country Link
US (1) US7989471B2 (de)
EP (1) EP1912995B1 (de)
JP (1) JP5426163B2 (de)
KR (1) KR101074673B1 (de)
CN (1) CN101233137B (de)
AP (1) AP2473A (de)
AR (1) AR055104A1 (de)
AT (1) ATE517902T1 (de)
AU (1) AU2006274858B2 (de)
BR (1) BRPI0614670A2 (de)
CA (1) CA2617095C (de)
DK (1) DK1912995T3 (de)
EA (1) EA014646B1 (de)
GT (1) GT200600341A (de)
HK (1) HK1116772A1 (de)
IL (1) IL188283A (de)
JO (1) JO2768B1 (de)
MX (1) MX2008001395A (de)
MY (1) MY152153A (de)
NO (1) NO20081071L (de)
NZ (1) NZ564541A (de)
PE (1) PE20070221A1 (de)
SG (1) SG163613A1 (de)
SI (1) SI1912995T1 (de)
SV (1) SV2008002639A (de)
TW (1) TWI412534B (de)
UY (1) UY29705A1 (de)
WO (1) WO2007014919A1 (de)

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US7741281B2 (en) 2005-11-03 2010-06-22 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
RU2008152171A (ru) * 2006-07-05 2010-08-10 Интермьюн, Инк. (Us) Новые ингибиторы вирусной репликации гепатита с
EP2049474B1 (de) 2006-07-11 2015-11-04 Bristol-Myers Squibb Company Hemmer des hepatitis-c-virus
EP2041156B1 (de) 2006-07-13 2013-11-20 Achillion Pharmaceuticals, Inc. 4-amino-4-oxobutanoyl-peptide als hemmer viraler replikation
US8343477B2 (en) 2006-11-01 2013-01-01 Bristol-Myers Squibb Company Inhibitors of hepatitis C virus
US7772180B2 (en) 2006-11-09 2010-08-10 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US8003604B2 (en) 2006-11-16 2011-08-23 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
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JP2014506255A (ja) 2010-12-30 2014-03-13 エナンタ ファーマシューティカルズ インコーポレイテッド フェナントリジン大環状ｃ型肝炎セリンプロテアーゼ阻害剤
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JP6038179B2 (ja) * 2012-01-11 2016-12-07 アッヴィ・インコーポレイテッド Ｈｃｖプロテアーゼ阻害剤の製造方法
AU2013329514A1 (en) 2012-10-08 2015-04-30 Abbvie Inc. Compounds useful for making HCV protease inhibitors
LT2909205T (lt) 2012-10-19 2016-12-27 Bristol-Myers Squibb Company 9-metilpakeistieji heksadekahidrociklopropa(e)pirolo (1,2-a)(1,4)diazaciklopentadecinilkarbamato dariniai, kaip nestruktūrinės 3 (ns3) proteazės inhibitoriai, skirti hepatito c viruso infekcijų gydymui
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Also Published As

Publication number Publication date
SI1912995T1 (sl) 2011-11-30
CA2617095C (en) 2014-05-13
UY29705A1 (es) 2007-05-31
EA200800484A1 (ru) 2008-06-30
IL188283A0 (en) 2008-04-13
NZ564541A (en) 2010-03-26
AR055104A1 (es) 2007-08-08
BRPI0614670A2 (pt) 2011-04-12
NO20081071L (no) 2008-04-25
EP1912995A1 (de) 2008-04-23
IL188283A (en) 2016-12-29
DK1912995T3 (da) 2011-10-24
GT200600341A (es) 2007-02-26
KR101074673B1 (ko) 2011-10-19
CA2617095A1 (en) 2007-02-08
CN101233137A (zh) 2008-07-30
US7989471B2 (en) 2011-08-02
US20100240698A1 (en) 2010-09-23
SG163613A1 (en) 2010-08-30
EA014646B1 (ru) 2010-12-30
WO2007014919A1 (en) 2007-02-08
AU2006274858A1 (en) 2007-02-08
SV2008002639A (es) 2008-07-23
MX2008001395A (es) 2008-04-16
JP5426163B2 (ja) 2014-02-26
AP2473A (en) 2012-09-24
AU2006274858B2 (en) 2012-05-24
HK1116772A1 (en) 2009-01-02
MY152153A (en) 2014-08-15
JP2009502882A (ja) 2009-01-29
KR20080041651A (ko) 2008-05-13
PE20070221A1 (es) 2007-04-16
EP1912995B1 (de) 2011-07-27
CN101233137B (zh) 2014-05-07
TWI412534B (zh) 2013-10-21
TW200745165A (en) 2007-12-16
JO2768B1 (en) 2014-03-15

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