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MX2017009863A - Agente preventivo y/o terapeutico de enfermedad inmune. - Google Patents

Agente preventivo y/o terapeutico de enfermedad inmune.

Info

Publication number
MX2017009863A
MX2017009863A MX2017009863A MX2017009863A MX2017009863A MX 2017009863 A MX2017009863 A MX 2017009863A MX 2017009863 A MX2017009863 A MX 2017009863A MX 2017009863 A MX2017009863 A MX 2017009863A MX 2017009863 A MX2017009863 A MX 2017009863A
Authority
MX
Mexico
Prior art keywords
prophylactic
therapeutic agent
immune diseases
compound
salt
Prior art date
Application number
MX2017009863A
Other languages
English (en)
Inventor
Hosoi Fumihito
Nakachi Yoshinori
KAJIWARA Daisuke
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of MX2017009863A publication Critical patent/MX2017009863A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se proporciona un agente preventivo y/o terapéutico para enfermedades inmunes que contienen un compuesto que tiene una actividad inhibidora de BTK o una sal del mismo, como un ingrediente activo; un agente preventivo y/o terapéutico de enfermedades inmunes, que comprende un compuesto representado por la fórmula (I), donde R1 a R3, W, X, Y, Z, y n representan los definidos en la especificación, o una sal del mismo, como un ingrediente activo. (ver Fórmula).
MX2017009863A 2015-01-30 2016-01-29 Agente preventivo y/o terapeutico de enfermedad inmune. MX2017009863A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015017386 2015-01-30
PCT/JP2016/052732 WO2016121953A1 (ja) 2015-01-30 2016-01-29 免疫疾患の予防及び/又は治療剤

Publications (1)

Publication Number Publication Date
MX2017009863A true MX2017009863A (es) 2017-11-15

Family

ID=56543555

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017009863A MX2017009863A (es) 2015-01-30 2016-01-29 Agente preventivo y/o terapeutico de enfermedad inmune.

Country Status (21)

Country Link
US (1) US9782412B2 (es)
EP (1) EP3120852B1 (es)
JP (1) JP6093485B2 (es)
KR (1) KR101858421B1 (es)
CN (2) CN113768935B (es)
AU (1) AU2016213030B2 (es)
BR (1) BR112017016278B1 (es)
CA (1) CA2975372C (es)
DK (1) DK3120852T3 (es)
ES (1) ES2734364T3 (es)
HU (1) HUE045532T2 (es)
MX (1) MX2017009863A (es)
MY (1) MY197518A (es)
PH (1) PH12017501336A1 (es)
PL (1) PL3120852T3 (es)
PT (1) PT3120852T (es)
RU (1) RU2705154C2 (es)
SG (1) SG11201704430SA (es)
TR (1) TR201910158T4 (es)
TW (1) TWI638817B (es)
WO (1) WO2016121953A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6093486B2 (ja) 2015-01-30 2017-03-08 大鵬薬品工業株式会社 縮合ピリミジン化合物の新規な塩及びその結晶
TW202135817A (zh) * 2019-12-19 2021-10-01 日商大鵬藥品工業股份有限公司 以縮合嘧啶化合物作為有效成分之治療劑
CN112209894B (zh) * 2020-10-23 2023-06-06 贵州医科大学 5-芳基取代2-氨基苯并恶唑类衍生物、制备方法及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007067781A2 (en) * 2005-12-08 2007-06-14 Abbott Laboratories 9-membered heterobicyclic compounds as inhibitors of protein kinases
PT2073810E (pt) * 2006-09-13 2011-09-30 Takeda Pharmaceutical Utilização de 2-6-(3-amino-piperidin-1-il)-3-metil-2,4-dioxo- 3,4-di-hidro-2h-pirimidin-1-ilmetil-4-fluoro-benzonitrilo para tratamento de diabetes, cancro, distúrbios auto-imunes e infecção por vih
CA2668286C (en) * 2006-11-03 2014-09-16 Pharmacyclics, Inc. Bruton's tyrosine kinase activity probe and method of using
JP2009235057A (ja) * 2007-10-31 2009-10-15 Santen Pharmaceut Co Ltd 血管新生阻害活性を有する新規インドール誘導体
US8338439B2 (en) * 2008-06-27 2012-12-25 Celgene Avilomics Research, Inc. 2,4-disubstituted pyrimidines useful as kinase inhibitors
AU2009262068C1 (en) 2008-06-27 2015-07-02 Celgene Car Llc Heteroaryl compounds and uses thereof
CA2841080A1 (en) * 2011-07-13 2013-01-17 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
WO2013108809A1 (ja) * 2012-01-19 2013-07-25 大鵬薬品工業株式会社 3,5-二置換ベンゼンアルキニル化合物及びその塩
JP2015526520A (ja) * 2012-08-31 2015-09-10 プリンシピア バイオファーマ インコーポレイテッド Itk阻害剤としてのベンズイミダゾール誘導体
JP6035423B2 (ja) * 2013-08-12 2016-11-30 大鵬薬品工業株式会社 新規な縮合ピリミジン化合物又はその塩

Also Published As

Publication number Publication date
JPWO2016121953A1 (ja) 2017-04-27
BR112017016278A2 (pt) 2018-03-27
TWI638817B (zh) 2018-10-21
KR20170083640A (ko) 2017-07-18
ES2734364T3 (es) 2019-12-05
JP6093485B2 (ja) 2017-03-08
CN113768935A (zh) 2021-12-10
RU2017127126A3 (es) 2019-03-01
BR112017016278B1 (pt) 2022-05-10
PT3120852T (pt) 2019-07-16
HUE045532T2 (hu) 2020-01-28
RU2017127126A (ru) 2019-03-01
RU2705154C2 (ru) 2019-11-05
KR101858421B1 (ko) 2018-05-15
AU2016213030B2 (en) 2019-01-31
EP3120852A1 (en) 2017-01-25
MY197518A (en) 2023-06-19
PL3120852T3 (pl) 2019-09-30
EP3120852A4 (en) 2017-05-24
AU2016213030A1 (en) 2017-06-22
PH12017501336A1 (en) 2017-12-11
US20170042900A1 (en) 2017-02-16
CA2975372C (en) 2020-01-14
CN113768935B (zh) 2024-10-01
CN107206001B (zh) 2021-09-28
SG11201704430SA (en) 2017-08-30
CN107206001A (zh) 2017-09-26
TR201910158T4 (tr) 2019-07-22
WO2016121953A1 (ja) 2016-08-04
TW201632526A (zh) 2016-09-16
CA2975372A1 (en) 2016-08-04
US9782412B2 (en) 2017-10-10
EP3120852B1 (en) 2019-05-01
DK3120852T3 (da) 2019-07-29

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