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Article
Open AccessChronic post-surgical pain after total knee arthroplasty: a narrative review
Total knee arthroplasty (TKA) is an efficacious treatment for end-stage knee osteoarthritis, often accompanied by severe postoperative pain. In certain patients, this pain can persist for over 3 months and is ...
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Article
Open AccessPerspectives of cancer consumer representatives on their involvement in healthcare service improvement: a qualitative study
Consumer involvement in healthcare service organisation and policy development is recognised globally as a vital strategy in improving the quality and patient-centredness of care. There are significant gaps in...
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Article
Open AccessN-acetylcysteine supplementation improves endocrine-metabolism profiles and ovulation induction efficacy in polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) affects 6–20% of women worldwide, with insulin resistance and hyperinsulinemia occurring in 50-70% of patients. Hyperinsulinemia exacerbates oxidative stress, contributing to P...
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Article
RGS22 maintains the physiological function of ependymal cells to prevent hydrocephalus
Ependymal cells line the wall of cerebral ventricles and ensure the unidirectional cerebrospinal fluid (CSF) flow by beating their motile cilia coordinately. The ependymal denudation or ciliary dysfunction cau...
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Open AccessThe short-term outcomes and risk factors of post-myocardial infarction ventricular septal rupture: a multi-center retrospective Study
Post-myocardial infarction ventricular septal rupture (PIVSR) is one of the most severe types of mechanical complications after acute myocardial infarction (AMI) with high mortality and poor prognosis. The ris...
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Article
Protective effect and mechanism of lycium barbarum polysaccharide against UVB-induced skin photoaging
Cellular senescence can be categorized into two main types, including exogenous and endogenous aging. Photoaging, which is aging induced by ultraviolet (UV) radiation, significantly contributes to exogenous ag...
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Article
Designing Optimal Probe Sequence for Breast Cancer Subtype Classification via Multiple MicroRNAs Recognition
Breast cancer is a heterogeneously manifested disease, categorized into several distinct molecular and pathological subtypes. Accurate subtype classification holds significant importance as it informs therapeu...
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Article
Association of the panimmune-inflammatory value (PIV) with all-cause and cardiovascular mortality in maintenance hemodialysis patients: a propensity score matching retrospective study
The panimmune-inflammatory value (PIV) is a novel inflammatory indicator. However, its role in maintenance hemodialysis (MHD) remains unclear. Our goal was to explore the predictive value of PIV for cardiovasc...
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Open AccessEffect of adductor canal block combined with infiltration between the popliteal artery and posterior capsular of the knee on chronic pain after total knee arthroplasty: a prospective, randomized, double-blind, placebo-controlled trial
Total knee arthroplasty (TKA) is accompanied by severe postoperative pain, which is reported to be an important cause of chronic pain. Ultrasound-guided adductor canal block (ACB) combined with infiltration be...
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Article
The Current State and Challenges of Clinical Ethics Consultation for Prenatal Diagnosis: A Qualitative Study of Committee Employee Perspectives in China
Clinical ethics consultations (CECs) play an important role in resolving ethical issues in clinical practice worldwide. The government has encouraged the development of CECs in China to address the ethical cha...
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Open AccessAnalyzing spatial delays of tuberculosis from surveillance and awareness surveys in Eastern China
The spatial delays of pulmonary tuberculosis (PTB) have been less explored. In this study, a total of 151,799 notified PTB cases were included, with median patient and diagnostic delays of 15 [interquartile ra...
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Ethical Challenges in Information Disclosure and Decision-making in Prenatal Testing: A Focus Group Study of Chinese Health Professionals in Maternal and Child Health Services
The international community has proposed a comprehensive strategy to prevent congenital abnormalities. And China, with a high incidence of congenital diseases, has implemented measures including prenatal scree...
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Article
Coupling effect of temperature, column height, properties of adsorbent and VOCs during dynamic adsorption
Dynamic adsorption is important for evaluating the Volatile Organic Compounds (VOCs) adsorption performance. During adsorption process, the exothermal characteristic could lead to an increase of the column tem...
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Article
Open AccessClinical heterogeneity and five phenotypes identified in pediatric Behçet’s syndrome: a cohort study from Shanghai Behçet’s syndrome database
Behçet’s syndrome (BS) is a rare disease of unknown etiology, with limited reports especially in pediatric BS. The clinical characteristics and phenotypes of pediatric BS as a highly heterogeneous variable ves...
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Article
Open AccessTrim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer
Breast cancer remains a significant global health challenge, and its mechanisms of progression and metastasis are still not fully understood. In this study, analysis of TCGA and GEO datasets revealed a signifi...
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Article
Extracting ship and heading from Sentinel-2 images using convolutional neural networks with point and vector learning
Obtaining accurate ship positions and headings in remote sensing images plays a crucial role in various applications. However, current deep learning-based methods primarily focus on ship position detection, wh...
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Article
Open AccessSecure computation protocol of Chebyshev distance under the malicious model
Secure multi-party computation of Chebyshev distance represents a crucial method for confidential distance measurement, holding significant theoretical and practical implications. Especially within electronic ...
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Article
Open AccessFactors associated with tuberculosis care-seeking and diagnostic delays among childhood pulmonary tuberculosis in Zhejiang Province, China: a 10-year retrospective study
We conducted a retrospective study to investigate risk factors for tuberculosis care-seeking delay and diagnostic delays among pediatric pulmonary tuberculosis cases in Zhejiang Province from 2013 to 2022. Amo...
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Biofuel cell–based self-powered immunosensor for detection of 17β-estradiol by integrating the target-induced biofuel release and biogate immunoassay
A novel biofuel cell (BFC)-based self-powered electrochemical immunosensing platform was developed by integrating the target-induced biofuel release and biogate immunoassay for ultrasensitive 17β-estradiol (E2...
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Article
Open AccessWhat are they considering when they face a fetus with birth defects? A qualitative study on ethical attitudes of health professionals in China
Birth defects are the leading cause of mortality in newborn babies and children under five years old. In response, the Chinese government has implemented a three-tiered prevention strategy, which has brought e...
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