DIExamPaper I (BIhar 98)
DIExamPaper I (BIhar 98)
DIExamPaper I (BIhar 98)
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a) Oral route b) Inhalation c) Sublingual d)Intrathecal
Q.3 A drug producing Cholestatic Jaundice is likely to be:
a)Chorpromazine b)Synthetic anabolic steroid c) Carbon tetrachloride d) Chloroform
Q.4 The action of heparin is anatagonised by :
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a) Menadione b) EDTA c) Naloxame d) Protamine sulphate
Q.5 Which of the following processes of biotransformation necessarily inactivates the
drug?
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a) Oxidation-reduction b) Hydrolysis c) Conjugation d) All of these
Q.6 Ethyl alcohol is metabolized in the liver by:
a) Reduction b) Oxidation c) Hydrolysis d) Conjugation
Q.7 An estimation of potency of a drug with reference to a standard on a biological
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Indicator is known as
a) Bioassay b) Biostandardization c) Biomedical reaction d) Biometrics
Q.8 Prolonged and repeated use of drugs may lead to form :
a) Hypersensitivity b) Tolerance c) Allergy d) Communication
Q.9 Drug absorption is better with :
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a) Insoluble drug b) Powders c) Lipid soluble drug d) Ionised
Q.10 A drug is introduced into the lumen of vein at least for one hour and the
administration is known as:
a) Intravenous Injection b) Intravenous infusion c) Intravenous drip d) All of these
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Q.23 Which of the followings is likely to be mediator of allergic reactions?
a) Histamine b) Dopamine c) Mepyramine d) Burimamide
Q.24 The preparing and dispensing of drug is known as :
a) Pharmacotherapeutics b) Pharmacy c) Pharmacology d) Pharmacognosy
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Q.25 Which animal tissue is most sensitive to acetylcholine for experiments in bioassay?
a) Rectus abdominis of frog b) Leech dorsal muscle c) Straub’s heart d) B.P. of
anaesthesized cat
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Q.26subcutaneously given drug shows longest duration of action if it given in the form of
a) Aqueous solution b) Pellets c) Aqueous suspension d) Oily suspension
Q.27 Enteric coated tablet release drug in the :
a) Stomach b) Small intestine c) Large intestine d) oral cavity
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Q.28 The quickest absorption of drugs takes place by:
a) Oral route b) I.M. route c) I.V. route d) Inhalation
Q.29 Which of the following gives you the best therapeutic index?
a) LD50/ED50 b) ED50/LD50 c) CD50/LD50 d) LD50/cD50
Q.30 For ventricular arrhythmia, the drug of choice is :
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a) Propranolol b) Lignocaine c) Dipheyl hydantoin d) Quinidine
Q.31 Mast cells are noted for their high content of Histamine and:
a) Norepinephrine b) Acetylcholine c) Epinephrine d) Heparin
Q.32 Drug used in acute bronchial asthma:
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a) 40 b) 38 c) 36 d) 34
Q.42 In pentose phosphate pathway G-6-P formation takes place utilizing 3 molecules of
G-6-P is :
a) 3½ moles of G-6-P b) 3 moles of G-6-P c) 2½ moles of G-6-P d) 2 moles of G-6-P
Q.43 The amino acid is responsible for the biosynthesis of catecholamine is
a) Typtophan b) Phenylalanine c) Cysteine d) Alanine
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Q.44 The invert sugar is :
a) Glucose b) Sucrose c) Starch d) Glycogen
Q.45 Rancidity of fat is due to oxidation of :
a) Saturated glycerides b) Unsaturated glycerides c) Both of a & b d) none of these
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Q.46 Amphoteric nature of protein is due to presence of :
a) -NH2 group & -COOH group b) –S – S bond c) –SH group & CH3 d) >C=O group
Q.47 The simplest and smallest amino acid is :
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a) Glycine b) Alanine c) Cystine d) Valine
Q.48 Which of the following fatty acids is essential fatty acid?
a) Stearic acid b) Butyric acid c) Archidonic acid d) Oleic acid
Q.49 Complete degradation of different amino acids in mammals takes places through :
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a) Embden mayerhof pathway b) Citric acid cyclic
c) Pentose pathway d) uronic acid pathway
Q.50 The enzymes of citric acid cycle are located in the :
a) Mitochondrial matrix b) Cytoplasm c) Endoplasmic reticulum d) All of these
Q.51 The antagonistic substance of prostaglandins is :
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a) Phospholipase b) Indomethacin c) Arylsulfatase d) Methysergide
Q.52 All pencillins show some degree of activity against
a) Gram-negative cocci b) Gram-postive cocci c) both a & b d) Virus
Q.53 In low concentration streptomycin is :
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Q.65 An antihypertensive drug which is alkaloid, is obtained from :
a) Rauwolfia serpentina b) Papaver somnifera
c) Digitalis purpurea d) Atropa belladonna
Q.66 When blood is placed in 0.89 % NaCl solution then there will be :
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a) Hemolysis b) No hemolysis c) Shrinkage of RBC d) Swelling of RBC
Q.67 When steam is passed through a water insoluble liquid, the mixture starts boiling :
a) The liquid attains its normal boiling temperature b) The mixture attains V.P. equal
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to the extranal pressure c) The liquid stains 1000C d) none of these
Q.68 For an ideal solution of two compounds A and B the V.P. of A is equal to Product
of V.P. of Compound B in pure state and :
a) The mole fraction of the compound A b) The moles fraction of the compound B
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c) No. of moles of compound A d) No. of moles of compound B
Q.69 At the triple point of water, there exists :
a) Four phase b) Three phase c) Two phase d) One phase
Q.70 The solubility of hydrated sodium sulphate increases with temperature upto 320C
And decreases with rise of temperature. This is due to :
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a) Initial endothermic reaction turns into exothermic reaction b) Ionization of sodium
sulphate c) Decomposition of sodium sulphate d) none of these
Q.71 When a liquid is poured to another liquid then the liquid will spread or not spread
And that depends on :
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a) S.T. of sublayer greater than sum of S.T. of spreading liquid and interfacial tension
between the sublayer and spreading liquid b) S.T. of sublayer is lesser than…….
c) S.T. of spreading liquid is greater than sublayer liquid d) S.T. of spreading liquid
is equal to sublayer liquid
Q.72 The content of Red Blood Cell cannot come out through cell membrane because :
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a) Size of molecule inside the cell is much bigger than the pore of membrane
b) Membrane shows a high degree of sensitivity of cell content c) There are no pores
in the membrane d) none of these
Q.73 A sea driver experience a pathological condition term ‘BENDS’ if he floats up very
Fast. This phenomenon can be explained by :
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Sodium acetate. The solution can offer a resistance to pH changes. The magnitude of
This resistance is known as
a) Co-efficient of buffer b) Buffer capacity c) Acid strength of solution
d) Basic strength of solution
Q.76 Standard EMF of a cell is defined as the measured EMF of a cell when :
a) Reactants have unit activity b) Products have unit activity c) Reactants and
products have unit activity d) Reactants and products have different activities
Q.77 The distribution coficient for iodine between water and carbon tetrachloride at 250C
Is K = C H2O/CCl4 = 0.012. to effect better extraction of 0.2 gm iodine in 100 ml
Water, how do you use 20 ml carbon tetrachloride?
a) 20 ml CCl4 at a time b) 20 ml CCl4 in portion taking 10 ml at a time c) 20 ml of
CCl4 in portion taking 5 ml at a time d) Does not depend on the volume of CCl4 for
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Effective extraction
Q.78 Heamoglobin is complex of metal. The metal present with heamoglobin is :
a) Copper b) Iron c) Manganese d) Cobalt
Q.79 Dialysis is used for purity of colloidal suspension from :
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a) Sugar b) Protein c) Ionic substances d) None of these
Q.80 Carbon has six electrons its outer shell but is :
a) Bivalent compound b) Trivalent compound c) Tetravalent compound
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d) Compound with variable valency
Q.81 Reversible change of state is the basic principle in pharmaceutical preparations
a) Inhaler b) Aerosols c) Implants d) none of these
Q.82 When solid salol is mixed with solid thymol, the mixture melts below their
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individual melting points. The lowest temperature at which both the solid and liquid
co-exist is called
a) Critical solution temperature b) Eutectic temperature
c) Critical temperature d) Lower critical temperature
Q.83 The ultraviolet light absorbed by organic compound causes :
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a) Molecular vibration b) Electronic excitation c) Both molecular vibration and
electronic excitation d) none of these
Q.84 Biologically active morphine molecule is :
a) Laevo rotatory b) Detro rotatory c) Racemic d) Optically inactive
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a) How far and how fast reaction will proceed b) Only how far a reaction will proceed
c) Only how fast a reaction will proceed d) Possibility of reaction
Q.90 The expiry date on the drug indicates that the concentration changes to :
a) half of its original concentration b) 0 % of its original concentration
c) 10 % of its original concentration d) Not related to its concentration but to its activity
Q.91 To prepare oil in water emulsion, the emulsifying agent must have HLB value in
the range of :
a) 0 – 3 b) 3 – 8 c) 8 – 16 d) 16 – 18
Q.92 Stability of a suspension can be predicted by measuring :
a) Nernst potential b)Zeta potential c) Density of suspension d)Viscosity of suspension
Q.93 Particle size can be determined by sedimentation method using :
a) Kelvin equation b) Stoke’s law c) Poiseuille’s equation d) Edmundson equation
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Q.94 Ethoxylated lanolin is :
a) Water soluble b) Oil soluble c) produce O/W emulsion d) Produce W/O emulsion
Q.95 Polyoxyethylene sorbitan monopalmitate is :
a) Polysorbate – 20 b) Polysorbate – 40 c) Polysorbate – 60 d) Polysorbate – 80
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Q.96 Specified limit of particles as per U.S.P. in case of large volume infusions are :
a) 50 particles of 10 μm and lesser per ml of large infusions b) 100 particles of 10 μm
and lesser per ml of large infusions c) 30 particles of 10 μm and lesser per ml of large
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infusions d) 10 particles of 10 μm and lesser per ml of large infusions
Q.97 Moist heat sterilization of nutrient agar involve the following :
a) 15 lbs pr sq. inch 15 mins. b) 15 lbs pr sq. inch ½ hr. c) 10 lbs pr sq. inch ½ hr
d) 20 lbs pr sq. inch 15 mins.
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Q.98 Melted(350C – 360C) Cocoa butter used as suppository base on snap cooling will
Produce
a) The v-form which slowly changes to β’-form b) The β’ form resist to α-form
c) The γ-form is obtained d) α-form is obtained
Q.99 The cash book records :
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a) All cash receipts b) All cash payments c) Both a & b d) Cash & credit safe of goods
Q.100 Profit and loss Account shows :
a) The financial position of the concern b) The degree of honesty with which
accounting work has been done c) The capital invested in the business
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40.c 41.c 42. 43.b 44.b 45.b 46.a 47.a 48.c 49.b 50.a 51.b 52.a
53.a 54.b 55.a 56.b 57.c 58.a 59.d 60.a 61.c 62.b 63.b 64.b 65.a
66.c 67.b 68.a 69.b 70. 71. 72. 73. 74.b 75.b 76.c 77. 78.b
79.c 80.c 81.b 82.b 83.c 84.a 85.c 86.c 87.c 88. 89.a 90.b 91.c
92.b 93.b 94. 95.d 96. 97. 98.a 99.c 100.d
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