Sdlp-Day 1 Mutation
Sdlp-Day 1 Mutation
Sdlp-Day 1 Mutation
I.OBJECTIVES
C. Learning Competencies/Objectives At the end of the lesson, the learners should be able to:
1. Define mutation
2. Translate codons using amino acid chart
3. Explain genetic mutation and the diseases it causes
4. Differentiate the two types of gene mutation and explain how mutations can cause changes in the structure of protein.
(S10LT-IIIe-38)
II.CONTENT
Heredity: Inheritance and Variation (Mutation)
III.LEARNING RESOURCES
A. References
3.Textbook Pages
IV.PROCEDURES
Yes, that's right! The two processes of CENTRAL DOGMA are translation and transcription. Transcription is the process of
copying DNA sequence into RNA, while translation is the process of converting information in mRNA into a sequence of amino
acids in a protein.
4. TAGENSMU- MUTAGENS
5. NODOC- CODON
C. Presenting examples/ instances of the The teacher will relate the motivational activity by letting the learners give and share their ideas about the activity by asking a
new lesson question/s.
(ENGAGE/EXPLORE)
Anyone from the class, who can give his/her idea/s about the lesson we will discuss today based on the words in first activity?
What is mutation?
What causes mutation?
What are the two types of genetic mutation?
What are the diseases caused by genetic mutation?
What are the three types of point mutation?
How mutation affects the structure of a protein?
MATERIALS: PowerPoint Presentation
2. Using the amino acid chart, write the sequence of amino acids of #1
TYROSINE-GLYCINE-PROLINE-LEUCINE
3. Edit the DNA strand in #1 by changing the second bases of ATG to A. Then write the sequence of amino acids.
DNA: AAG CCC GGC GAG
mRNA: UUC-GGG-CCG-CUC
PHE-GLY-PRO-LEU
4. This time. Edit the DNA strand in #1 and write an additional A after ATG.
DNA: ATG ACC CGG CGA G
mRNA: UAC-UGG-GCC-GCU-C
tRNA: AUG-ACC-GCC-CGA-G
TYR-TRP-ALA-ALA
5. Edit the original DNA strand in #1 and replace the CCC with CCA
DNA: ATG CCA GGC GAG
mRNA: UAC-GGU-CCG-CUC
tRNA: AUG-CCA-GGC-GAG
TYR-GLY-PRO-LEU
6. Write your simple observation on the activity.
G. Finding practical applications of Cite practical applications of Mutations in our daily life. (5 mins)
concepts and skills in daily living.
(ELABORATE)
B. Enumeration
J. Additional activities for application or Read more about the different types of chromosomal mutation. (2 mins)
remediation (EXTEND)
V. REMARKS
VI. REFLECTION
JESSICA L. SUDIO MARIA LUISA L. CAGUIOA CRISTINA M. CERVANTES, EdD ROSARIO C. FERRER, EdD
Teaching Intern Coordinating Teacher HT-III, Science Department Principal IV