Day 1
Day 1
Day 1
I. OBJECTIVES
A. Content Standards Mutations that occur in sex cells as being heritable
B. Performance
Standards
C. Learning Explain how mutations may cause changes in the structure and function
Competencies/Objectives of a protein.
(Write the code for each S10LT-IIIe-38
LC)
D. Specific Objective/s 1. Illustrate gene and chromosomal mutation through the use of models.
E. Integration of Content
Within and Across
Curriculum
II. CONTENT
A. Subject Matter Gene and Chromosomal Mutation
III. LEARNING
RESOURCES
A. References
1. Teacher’s Guide
Pages
2. Learner’s Material 281-288
Pages
3. Textbook Pages
4. Additional Materials
from LR Portal
B. Other Learning https://www.youtube.com/watch?v=GieZ3pk9YVo
Resources
IV. PROCEDURES Teacher’s Activity/ies Learner’s Expected
Response/s
A. Reviewing previous Elicit (2 minutes)
lesson or presenting When you copy from the blackboard, sometimes
the new lesson you may make mistakes, right? - Yes
In a similar way, mistakes may occur when DNA
is replicated.
Look at the figure.
https://www.slideshare.net/JEvzOlliuqNobrac/sci10-lm-
u32
Guide questions: -2
1. How many chromosomes are involved? - Broke a part and
2. How did you change the original structure of attached it to another
the chromosomes? chromosome.
3. Which condition/s do you think result/s to - Either gain or loss
change/s of chromosome material? of genetic material
(Please indicate using the words loss, gain, OR no loss or gain of
either loss or gain of genetic material.) genetic material
during the exchange
Group 2: Deletion process
A. Make a model of a chromatid (one of the
duplicated copies of a chromosome).
B. When done, remove a portion of it (close to
either end of the chromosome or within the long
arm or short arm). If you choose to remove a
part within the arms, be sure to join back the
bottom part.
161
https://www.slideshare.net/JEvzOlliuqNobrac/sci10-lm-
u32
Guide questions:
1. How many chromosomes are involved?
2. How did you change the original structure of
the chromosomes?
3. Which condition/s do you think result/s to -1
change/s of chromosome material? - Broke a part
(Please indicate using the words loss, gain, - Loss of genetic
either loss or gain of genetic material.) Material
Group 3: Inversion
A. Make a colored chromatid.
https://www.slideshare.net/JEvzOlliuqNobrac/sci10-lm-
u32
B. This time break a portion (with 2 colors) of it.
https://www.slideshare.net/JEvzOlliuqNobrac/sci10-lm-
u32
https://www.slideshare.net/JEvzOlliuqNobrac/sci10-lm- -1
162
H. Making
generalizations and https://www.slideshare.net/JEvzOlliuqNobrac/sci10-
lm-u32
abstractions about the
lesson
If mutation is severe, the resulting protein may
be nonfunctional, and the embryo may not
develop.
163
B. Body cells
- Some mutations in a body cell are known to
cause cancer while mutations in sex cells can
cause birth defects.
Source: education-portal.com
V. REMARKS
VI. REFLECTION
A. No. of learners who
earned 80% on the
formative assessment
B. No. of learners who
require additional
activities for
remediation
C. Did the remedial
lessons work? No. of
learners who have
caught up with the
lesson
D. No. of learners who
continue to require
remediation
E. Which of my teaching
strategies
F. What difficulties did I
encounter which my
principal or supervisor
can help me solve?
G. What innovation or
localized materials
did
I use/ discover which
I
wish to share with
other teachers?
Activity Chromie Change
165
Objective:
1. Illustrate the kinds of chromosomal mutations
2. Differentiate the kinds of chromosomal mutations
Procedure:
1. Using modeling clay, make models of two (2) chromosomes. One should have a different color
and size from the other.
2. Break one part of each of the chromosomes. Exchange the parts and attach them to each of the
other chromosomes. See illustration below.
Guide questions:
1. How many chromosomes are involved?
2. How did you change the original structure of the chromosomes?
3. Which condition/s do you think result/s to change/s of chromosome material?
(Please indicate using the words loss, gain, either loss or gain of genetic material.)
Guide questions:
1. How many chromosomes are involved?
2. How did you change the original structure of the chromosomes?
3. Which condition/s do you think result/s to change/s of chromosome material?
(Please indicate using the words loss, gain, either loss or gain of genetic material.)
166
Guide questions:
1. How many chromosomes are involved?
2. How did you change the original structure of the chromosomes?
3. Which condition/s do you think result/s to change/s of chromosome material?
(Please indicate using the words loss, gain, either loss or gain of genetic material.)