SALAZAR COLLEGES OF SCIENCE AND INSTITUTE OF TECHNOLOGY

211 N. Bacalso Avenue, Cebu City

COLLEGE OF NURSING
DRUG STUDY
Student’s Name: EBRADA, LLANTO, PEDRANO, TANCIO, & TOJONG Patient’s Initial :_____________
Area : COMMUNITY HEALTH NURSING- RLE Patient’s Diagnosis:_________
Clinical Instructor : Jiovilito Arcala, RN
DRUG INDICATIONS MECHANISM OF ACTION ADVERSE EFFECTS NURSING RESPONSIBILITIES
Generic Name: CLASSIFICATION May inhibit the central CNS: Angina Specific:
 Methyldopa is a vasomotor centers, Bradycardia  Assess blood pressure
Methyldopa
decreasing sympathetic Orthostatic (BP) periodically and
Brand Name: centrally acting
outflow to hypotension compare to normal
sympatholytic agent the heart, kidneys, and Depression values
Aldomet
used in the peripheral vasculature. Dizziness  Document whether
Dosage: treatment of Lethargy drug therapy is
Adults—Tablets: 125 hypertension. Alpha-methyldopa is Sedation successful in
mg , 250 mg, 500 mg converted to methyl Rash controlling
norepinephrine centrally Gynecomastia hypertension.
to decrease the Impotence  Also measure BP
Route:  This drug is also adrenergic outflow by Dry mouth when patient
PO- Give tablets with useful in pregnancy alpha-2 agonistic action Nausea assumes a more
water on an empty because it has no from the central nervous Vomiting upright position (lying
stomach at least 30 teratogenic effects. system, leading to Hemolytic anemia to standing, sitting to
minutes before first reduced total peripheral Thrombocytopenia standing, lying to
meal of the day. resistance and decreased Liver toxicity sitting).
systemic blood pressure. Arthralgia  Document orthostatic
Onset: Autoimmune disease hypotension and
4–6 hours after oral Lupus-like syndrome contact physician
administration.  Belongs to the when systolic BP falls
general class of >20 mm Hg or
Peak: medicines CONTRAINDICATIONS diastolic BP falls >10
effective for 6–12 hours called antihypertensi mm Hg.
ves. It is used to treat Contraindicated in General:
patients Monitor patient's BP
high blood pressure
hypersensitive to drug regularly. Elderly patients are
Frequency: (hypertension)
and in those with more likely to
b.i.d. to t.i.d. in first 48 active experience hypotension,
hours. Increase if hepatic disease (such syncope, and sedation.
needed every 2 days. as acute hepatitis) or • Occasionally, tolerance
Pharmacologic: Centrally
acting antiadrenergics active cirrhosis. may occur, usually between
• Contraindicated in the second and third
those whose previous months of therapy. Adding a
methyldopa therapy diuretic or adjusting dosage
Therapeutic: caused liver may be needed. If
Antihypertensives problems and in those patient's response changes
taking MAO inhibitors. significantly, notify
• Use cautiously in prescriber.
patients with history • After dialysis, monitor
Pregnancy Category Risk: of impaired hepatic patient for HTN and notify
There are no well- function or prescriber, if needed.
controlled studies in sulfite sensitivity. Patient may need an extra
pregnant women in the dose of drug.
• Monitor CBC with
first
differential counts before
trimester. Use only if therapy and periodically
thereafter.
clearly needed. Available
data show use during

pregnancy doesn't cause

fetal harm and may
improve fetal outcomes.