CURRICULUM VITAE

Hanny Nilasari, MD
(Consultant of Dermatovenereologist)
Department of Dermatovenereology,
Faculty of Medicine Universitas Indonesia -
Cipto Mangunkusumo National Hospital (FMUI-RSCM)
January 31st, 1967
Jl. Cempaka Putih Tengah 32/II A, Jakarta 10510
Email: hannynilasari.deptkulitrscm@gmail.com
Phone: +6221-42879480/818989426

EDUCATION
1992 Medical Doctor, Unika Atmajaya, Jakarta
2002 Dermatovenereology Specialist, FMUI-RSCM, Jakarta
2014 Consultant of STI, Dermatovenereology Colegium,
FKUI-RSCM, Jakarta
PROFESSIONAL EXPERIENCES
2003 - Present STI Division of Dermatovenereology Department, FMUI-RSCM
2005 - 2014 Staff of Undergraduate Program Coordinator, FMUI-RSCM
2014 - Present Coordinator of Undergraduate Program, Dermatovenereology
Department, FMUI-RSCM
2017 - Present Chairman of IMS Study Group Indonesia – Perdoski
2020 - Present Head of Dermatovenereology Department, FMUI-RSCM
FELLOW

2011 Fellow of Asian Academy Dermatology and Venereology (FAADV)

2011 Fellow of Indonesian Society Dermatology and Venereology (FINSDV)

ORGANIZATION
2002-2005 Secretary, Indonesian Society of Dermatology and Venereology
(PERDOSKI)-Jakarta
2005-2011 Division of Organization, PERDOSKI-Jakarta
2008-2014 Secretary of Indonesian Herpes Study Group (KSHI) PERDOSKI
Secretary of STI Study Group (KSIMSI) PERDOSKI
2014-2017 Head of KSHI PERDOSKI
 2014-2017 Treasurer of ISTISG PERDOSKI
2011 - 2017 Vice Secretary of PERDOSKI
2014 - Present Committee of Sub-Panitia Ahli Pokja Penelitian dan Laboratorium, P2PL,
Indonesian Health Ministry
2015-present Secretary of Steering Committee HIV/AIDS, P2PL,
Indonesian Health Ministry
- Member of team development executive clinic RSCM
2016 - 2019 - Member of team development RSUI Depok
2016 Committee of PIT PERDOSKI XV
2018 Committee of DEVICE Symposium 2018, FKUI RSCM
2018 Chairman of Acne Scar Treatment Workshop, RSCM
2018 Committee of ICMI Socialization Programme “Saving the Indonesian
Young Generation from Moral Disaster in Deviant Behavior of LGBT“
2017 -2020 Chairman of Indonesian Sexually Transmitted Infection Study Group
2017 - 2020 General Secretary of Indonesian Society of Dermatology and
Venereology
2019 Vice Chairman of PIT PERDOSKI XVII
2019 Chairman of “Laser and Light Based Devices in Dermatology” Workshop,
RSCM
RESEARCH & PUBLICATION: FIRST AUTHOR
2008 Antimicrobial Resistance Pattern of Neisseria Gonorrhoeae in High Risk
Women Population: A Study in Karya Wanita Social Rehabilitation House
of Social Department, Mulya Jaya, Pasar Rebo, Jakarta, KONAS XII
PERDOSKI Palembang, 2007
2010 The efficacy of Sirih Merah Extract Wash to Reduce Woman Physiological
Discharge
2011 A Comparison Study: Effectivity and Safety Between Combination of
Retinoic Acid 0,05 %, Hidroquinone 4% with Flucinolone Asetonide 0,01%
Cream and Combination of Retinoic Acid 0,05% with Hidroquinone 4% for
Treatment of Melasma in Indonesian Patients
2014 Sexual Transmitted Infection Prevalence and Social Perspective amongs
Commercial Sexual Female Workers in Panti Sosial Karya Wanita (PSKW)
Mulya Jaya, Indonesian Social Ministry, Pasar Rebo
RESEARCH & PUBLICATION: NON-FIRST AUTHOR
2007 Recurrent Vulva and Oral Ulcer amongs Behcet Disease Suspects, Media
Dermato-Venereologica Indonesiana (MDVI), Vol. 34, No. 2, Hal: 51-104
2007 Normal and Transient Skin Conditions in Neonates, Media Dermato-
Venereologica Indonesiana (MDVI), Vol. 34, No. 3, Hal: 104-145
2008 Successful Used of Tingtura Podofilin 25% as Therapy for Giant
Condyloma Acuminatum in AIDS patients, Abstract Books, KONAS XII
PERDOSKI, Palembang
2008 Squamous Cell Carcinoma Clinical Lesion in Condiloma Acuminata, Buku
Abstrak KONAS XII PERDOSKI, Palembang
2008 Neisseriae gonorrhoeae Resistency to antibiotics in high risk women
2009 Histopatological Diagnosis of Giant Cell Fibroblastoma, Buku Makalah
Lengkap, PIT X PERDOSKI, Banten
2010 The efficacy of Sirih Merah Extract Wash to Reduce Woman Physiological
Discharge
2010 Efficacy of Podophylin Tincture 25% on Giant Condyloma Patient with HIV
2010 Pregnancy In A Married Couple With Syphilis and HIV Infection
2013 Xanthelasma, Clinical appearance and it’s Manifestation
2014 Clinicopathology correlation on Hyperpigmented skin disorder
2014 Perbandingan efektivitas dan keamanan terapi Krim kombinasi asam
retinoat 0,05%, Hydroquinone 4%, dan flusinolon asetonid 0,01% dengan
kombinasi asam retinoat 0,05% dan hidrokuinon 4% untuk terapi
melasma pada orang Indonesia
2015 Prevalence of Mycoplasma hominis and Ureaplasma urealyticum
infection in female Sex Workers and it’s association with douching: A
Study in East Jakarta, Indonesia using Mycoplasma System Plus
2016 Vaginal Microbiota on Menopasue
2016 Pulsed Dye Laser Efficacy In the treatment of psoriasis in adult patients:
An Evidence Based Case Report
2017 Venous Ulcer
2017 Asymtomatic Congenital Neurosyphilis: A Case Report
2018 Genital Human Papilomavirus Infection in Nonclasical Clinical Lesion of
Condyloma Acuminata in Ciptomangunkusumo Hospital
 2019 Relationship Between The Prevalence of Maternal Syphilis and HIV with
The Prevalence of Congenital Syphilis in WHO South East ASIA Region: A
Systematic Review
2019 Is Syphilis on The Rise?
EDITOR/CONTRIBUTOR
2006 Guideline of STI Treatment, Indonesian Health Ministry, Dirjen P2MPL,
Jakarta
2006 Implementation of STI Prevention Program amongs Commercial Sexual
Female Workers as a Comprehensive Management of STI, Ditjen PPMPL,
WHO, Jakarta
2007 National Strategy and Plan of STI and SRI Control, 2008-2012
2010 Guideline of STI Management, Indonesian Health Ministry, Dirjen P2MPL,
Jakarta (Revision)
2010 Guideline of Humanus Virus Management, KSHI, 2010
2012 Guideline of STI Management and Laboratory Strategy in Primary Care,
Indonesian Health Ministry, Dirjen P2MPL, Jakarta (Revised Edition)
2014 Committee of Perdoski Clinical Practice Guideline
2016 Indonesian STI Guideline 2016
2017 Manifestation and Treatment of Dermatology and Venereology Disorders
in HIV/AIDS Patient
2017 Dermatology and Venereology Book
2017 Editor of Infeksi Menular Seksual Book
2019 Indonesian STI Guideline 2019
2019 Prevention of HIV, Syphilis, and Hepatitis B from Mother to Child
Transmission Guideline
2019 Guideline of STI Management and Laboratory Strategy in Primary Care,
Indonesian Health Ministry, Dirjen P2MPL, Jakarta (Revised edition)
2019 Editor of Edukasi Kesehatan Reproduksi (E-Kespro) for Non medical
Personel Module for Duta Nelayan Training Programme, Harapan Island,
Thousand Island.
SPEAKERS IN SCIENTIFIC MEETING (NATIONAL/INTERNATIONAL)
2005 Evidence Based Medicine in Daily Practice, Kursus Penyegar dan
Penambah Ilmu Kedokteran (KPPIK), FMUI, Jakarta
2008 Skin and Genital Health Update in Daily Clinical Practice
2013 Anal Neoplasia Study in Asia Pacific, Bangkok
2014 High Resolution Anoscopy Refresher Study, Bangkok
2004 Yearly Scientific Meeting/Pertemuan Ilmiah Tahunan (PIT) VIII PERDOSKI
2004 Comprehensive Approach of Diabetic Patients,
RS Omni Medical Center, Jakarta
2005 Dermatovenereology: Entering the Era of Evidence Based Medicine,
KONAS XI PERDOSKI
2005 HIV/AIDS Counselling Training, POKDISUS AIDS FKUI-RSCM,
RSK Dharmais and Yayasan Pelita Ilmu
2006 Seminar “Anticipating Sindroma 3 Tempat Praktek”, Ikatan Rumah Sakit
Pendidikan Indonesia
2006 The 3rd Indonesian Medical Education Meeting and Expo (PEPKI III) AIPKI
2006 Whorkshop “Academic Evaluation in 2005 Competency Based
Curriculum/Kurikulum Berbasis Kompetensi (KBK)”, FMUI, Jakarta
2008 12 Roles of Medical Teacher, Seminar, FMUI, Jakarta
2008 2008 Dermatology Update and Symposium, National Skin Center
2008 Increasing Professionalism and Competency of Dermatovenereologist as
a Dermatogeriatric Prevention Strategy, KONAS XII PERDOSKI, Palembang
2008 Wokshop of Laser and Light Treatment, KONAS XII PERDOSKI, Palembang
2008 Seminar “Your Healthy Skin, Your Confidence”, FMUI, Jakarta
2009 Penatalaksanaan Terkini Penyakit Selama Kehamilan, The Indonesia
Medical Association (IDI), FMUI, Jakarta
2010 PIT PERDOSKI
2011 KONAS PERDOSKI, Manado
2015 In House Training of Medical Writing in Dermatovenereology Study,
CEEBM-Dermatovenereology Department, FMUI-RSCM
2016 PIT PERDOSKI XV
2017 HIV/AIDS and STI presentation at Panti Sosial Karya Wanita Mulya Jaya
2017 Dermatovenereology knowledge and skills training in Primary Health
Facilities
2017 KPPIK
2018 Regional Conference of Dermatology 2018
2018 National Seminar about STI and HIV/AIDS with ICMI
2019 Resource person at Sumber Suara Medika
 2019 1st EAST INSDV
2019 Mismanaged cases Symposium, Banten
2019 STI New Insight and Future Challenges advances Symposium and
Workshop, Surakarta
2019 Recent Clinically Applied: Comprehensive Diagnostic and Management of
STI in Daily Practice, Surabaya
2019 PIT PERDOSKI XVII
2019 National Seminar by ICMI at Universitas Tanjung Pura, Universitas Negeri
Padang, Universitas Islam Nasional Syarif Hidayatullah, Universitas
Teknokrat Lampung, Universitas Bandar Lampung, Universitas
Muhammadyah Surakarta, Universitas Diponegoro, Institut Pertanian
Bogor, Institut Teknologi Surabaya, Universitas Gunadarma Jakarta
2019 “Sexually Transmitted Infection” presentation at Duta Nelayan Training
Programme, Harapan Island, Thousand Island
2019 “STI Management in Primary Health Facilites” at Sudinkes Kepulauan
Seribu Office
COMMUNITY SERVICE
2006-2007 Lecture of STI and HIV/AIDS amongs High Risk Population (Sexual Female
Workers) PSKW Mulyajaya, Pasar Rebo, Depsos RI (Quarter-yearly)
2007-2008 Lecture of STI and HIV/AIDS amongs High Risk Population (Sexual Female
Workers) PSKW Mulyajaya, Pasar Rebo, Depsos RI (Quarter-yearly)
2008-2009 Lecture of STI and HIV/AIDS amongs High Risk Population (Sexual Female
Workers) PSKW Mulyajaya, Pasar Rebo, Depsos RI (Quarter-yearly)
2009-2010 Lecture of STI and HIV/AIDS amongs High Risk Population (Sexual Female
Workers) PSKW Mulyajaya, Pasar Rebo, Depsos RI (Quarter-yearly)
2010-2011 Lecture of STI and HIV/AIDS amongs High Risk Population (Sexual Female
Workers) PSKW Mulyajaya, Pasar Rebo, Depsos RI (Quarter-yearly)
2010-2011 Annual Lecture of STI and Safe Sex Practice as STI Prevention Strategy
amongs High Risk Population, PS Bina Karya, Gelandangan dan Anak
Jalanan, Departemen Sosial RI
2019 Community Services of 1st East INSDV, Papua
2019 Lecture of STI in Duta Nelayan Training Programme, Harapan Island,
Thousand Island
2019 Health promotion to community in World AIDS Day 2019, Jakarta
TRAINING
2007 Prevention of Disability (MH)
2007 Facial Rejuvination Training using Filler and Botox
2007 Liposuction, Lipofilling and Laser Lipolysis
2008 What is (Procedural) Dermatologic Surgery in 2008 and how does
Indonesian Compare?
2008 Laser and Light Treatment
2009 PEKERTI
2009 Good Clinical Practice
2009 Atopic Dermatitis
2014 Item Development and Review
2015 Dermoscopy in Skin Tumor
2015 Lokakarya Program Pendidikan Dokter Spesialis
2019 Clinical Research Protocol Writing Workshop (CRIPIK 2019)
 Hanny Nilasari
Gonore: Staf Medis

Manifestasi Klinis, pencegahan D e p a r t e m e n D e r m a t o l o g i d a n Ve n e r e o l o g i

FKUI/RSCM
penyakit, dan pengendalian penyakit K E L O M P O K S TUDI I N F E K S I
M E N U L AR S E K S U AL I N D O N E S I A P E R D O S K I

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 Pendahuluan

• Infeksi Menular Seksual (IMS) masih merupakan masalah kesehatan

masyarakat di seluruh dunia
▶ Lebih dari 1 juta orang setiap hari tertular IMS yang dapat
disembuhkan
▶ Sifilis, gonore, herpes genital → risiko tertular HIV ≥ 3x
▶ Penularan IMS dari ibu ke anak → morbiditas dan mortalitas ibu dan anak
▶ Gonore dan klamidia → infertilitas
▶ Infeksi Humuan Papiiloma Viru (HPV) dan Herpes simplex virus (HSV) →
gangguan psikologis
▶ Infeksi HPV → kanker serviks
▶ Resistensi antibiotik pada gonore
World health organization. Guideline for management of symptomatic STI. 2021. THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND
LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021
World health organization. Global health sector strategy on sexually transmitted THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND
LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021
infections 2016- 2021 towards ending STIs. 2016:39.
 Target global yang dicanangkan WHO untuk mengakhiri
epidemi IMS, yaitu agar pada tahun 2030 tercapai:

▶ Pengurangan insidens global T. pallidum hingga 90% (global baseline

tahun 2018).
▶ Pengurangan insidens global N. gonorrhoeae hingga 90% (global
baseline tahun 2018).
▶ Kasus sifilis kongenital mencapai 50 atau kurang per 100.000 kelahiran
hidup pada 80% negara.
▶ Program vaksinasi HPV masuk dalam program imunisasi nasional
berbagai negara

Kementerian Kesehatan Republik Indonesia. Pedoman nasional infeksi THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND
menular seksual. 2020:6. LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021
 Penatalaksanaan IMS komprehensif
▶ Anamnesis & pemeriksaan fisis ▶ Pre-exposure prophylaxis (PrEP)
▶ Diagnosis tepat ▶ Intervensi pencegahan:
▶ Terapi efektif • Program triple eliminasi HIV, sifilis,
▶ Edukasi dan konseling tentang infeksi dan hepatitis B
mengurangi risiko • Vaksinasi hepatitis A & B, HPV
▶ Kepatuhan berobat • Sirkumsisi
▶ Penggunaan kondom • Pre-exposure prophylaxis (PrEP)
▶ Pemeriksaan yang tepat dan • Pengendalian resistensi obat
pengobatan pasangan seksual
▶ Follow up

World health organization. Guideline for management of symptomatic STI. 2021: 20. THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND
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Intervensi perilaku sebagai bagian prevensi
Prioritas pada populasi khusus (termasuk populasi kunci untuk HIV),
remaja, dan perempuan hamil.

Apa yang termasuk intervensi ?

1. Edukasi untuk meningkatkan kewaspadaan terhadap infeksi menular seksual
2. Mengurangi jumlah pasangan seks,
3. Meningkatkan serapan penapisan /skrining IMS dan HIV,
4. Menunda hubungan seks pertama kali, dan
5. Edukasi penggunaan kondom

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Anamnesis Infeksi Menular Seksual
• Keluhan utama
• Kapan keluhan utama timbul (masa inkubasi)
• Mencari penyebab dari keluhan
• Mencari faktor risiko IMS pada pasien dan pasangannya
• Mencari apakah ada tanda dan keluhan IMS lain
• Mencari komplikasi
• Riwayat pengobatan dan responnya
• Riwayat alergi obat

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 Agar tujuan dapat tercapai, dibutuhkan
kemampuan komunikasi yang baik, terdiri dari
komunikasi verbal
(cara berbicara dan bertanya) dan komunikasi
non-verbal (Bahasa tubuh/body language).

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Keluhan IMS
1. Duh/sekret/cairan vagina
2. Duh/secret/cairan uretra
3. Luka pada alat kelamin (Ulkus genital)
4. Nyeri perut bag bawah pada Wanita
5. Pembengkakan skrotum/buah pelir
6. Benjolan di lipat paha (Bubo inguinal)
7. Radang mata bayi baru lahir (Konjungtivitis Neonatorum)
8. Tumbuhan pada alat kelamin (Vegetasi Genital)
9. Prokitis daerah anus

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Diagnosis Infeksi menular
seksual
▪ Pendekatan sindrom – bila tidak ada sarana
laboratorium
▪ Bila fasilitas laboratorium tersedia: etiologis
▪ Kendala: waktu, alat, sumber daya, biaya,
sensitivitas dan spesifisitas tes yang perlu diujikan,
tidak semua lokasi mempunyai laboratorium
▪ Saat ini masih dilaksanakan dan dikembangkan
penatalaksanaan kasus IMS berdasarkan pendekatan
sindrom untuk semua fasilitas kesehatan dasar
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 Infeksi gonore
Gonore----semua penyakit yang disebabkan oleh Neisseria
gonorrhoeae.
Spesies lain : N. meningitidis serta dua spesies yang bersifat
komensal, yaitu N. catarrhalis, dan N. pharyngis sicca.
Keempat spesies ini sulit dibedakan kecuali dengan tes
fermentasi.

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Klinis
Infeksi gonore dapat berupa : infeksi lokal asimtomatik/tidak bergejala, infeksi lokal
simtomatik/bergejala, infeksi lokal komplikasi, maupun penyebaran secara sistemik diseminata.
Gambaran klinis dan perjalanan penyakit dapat berbeda antara perempuan dengan laki-laki
akibat perbedaan anatomi dan fisiologi.
Umumnya pada perempuan penyakit lebih sering asimtomatik.
Infeksi asimtomatik biasanya terjadi pada organ uretra, endoserviks, rektum, dan faring
sedangkan infeksi simtomatik menyebabkan urethritis, servisitis, proktitis, faringitis, bartolinitis,
dan konjungtivitis.
Komplikasi lokal yang dapat terjadi berupa salpingitis, epididimitis, abses Bartholin, limfangitis,
edema penis, abses periuretra, dan prostatitis sedangkan penyebaran sistemik diseminata lebih
jarang terjadi

THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND

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 Vaginitis/servisitis gonore pada
perempuan

THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND

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Uretritis,
faringitis, dan
proktitis gonore

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 Diagnosis
Ditegakkan berdasarkan
➢anamnesis
➢pemeriksaan fisik, dan
➢pemeriksaan penunjang
➢ Pemeriksaan penunjang yang ideal:
sensitivitas tinggi, spesifik, cepat dan tidak
mahal.

➢Berbagai metode telah ditemukan untuk membantu menegakan diagnosis yaitu dengan cara presumptive
diagnosis, isolasi, identifikasi dan deteksi molekular

THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND

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 Presumptive Diagnosis
Penggunaan mikroskop dengan pewarnaan Gram untuk
menentukan adanya diplokokus gram negatif intrasel -→ cara
presumptive diagnosis yang paling banyak digunakan.
Diagnosis Kelebihan
❖mudah, tidak mahal, dan cepat sehingga mampu
memudahkan tatalaksana dan mencegah transmisi. dengan
pewarnaan Gram.

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 Sensitivitas pemeriksaan bergantung pada:
1. Jenis bahan yang diambil, misalnya uretra laki-laki–
90%, dari sekret serviks perempuan ---30-50%
Presumptive
2. flora normal kontaminan di vagina: makin banyak,
diagnosis
sensitivitas makin rendah
3. lokasi: sensitivitas pemeriksaan rendah bila specimen berasal
dari rectum, atau faring--- karena banyak bakteri

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 ➢pemeriksaan baku emas pada infeksi gonore.
➢Media pertumbuhan yang disarankan antara lain Thayer-Martin atau
modified New York City atau modified Thayer-Martin atau agar cokelat
McLeod.
➢Media Thayer-Martin ini kaya akan pepton dan zat pati ditambahkan pula
sumber besi dan faktor pertumbuhan sehingga selektif dalam mengisolasi
gonokokus, mengandung vankomisin untuk menekan pertumbuhan gram
positif, mengandung kolinestat untuk menekan pertumbuhan Gram negatif,
dan nistatin untuk menekan pertumbuhan jamur.

Isolasi Kultur ➢Media transport yaitu Stuart’s atau Amies yang harus diletakan pada media
pertumbuhan dalam 48 jam.
➢N. gonorrhoeae membutuhkan lingkungan yang hangat, lembap,
kelembapan tinggi (>90%) dengan 5-7% karbondioksida pada 36⁰C selama
minimum 48 jam.
➢Pemeriksaan kultur dari duh uretra laki-laki memiliki sensitivitas yang lebih
tinggi (94-98%) dibandingkan dengan duh endoserviks (85-95%) dan
spesifisitas keduanya lebih dari 99%.
➢Metode identfikasi bakteri dengan kultur membutuhkan waktu yang lama
dan cukup mahal sehingga jarang digunakan secara rutin

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 Tes oksidasi menggunakan reagen tetrametil-p-fenilendiamin
hidroklorida 1% -→ reaksi positif berupa perubahan warna koloni
yang semula bening menjadi merah mudah sampai merah
lembayung.
Dilanjutkan dengan tes fermentasi menggunakan reagen yang
Identifikasi mengandung glukosa, maltosa, dan sukrosa.
Koloni Bakteri gonokokus hanya meragikan glukosa saja. Tes beta-
laktamase menggunakan,cefinase TM disc 3 BBL96192 yang
mengandung sefalosporin kromogenik.
Bakteri yang mengandung beta laktamase menyebabkan
perubahan warna koloni dari kuning menjadi merah

THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND

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 Pemeriksaan ini : sensitifitas yang tinggi dan hasil yang cepat bila
dibandingkan dengan kultur.
Deteksi molekular adalah Nonamplified DNA probe test, nucleic
acid amplification tests (NAATs), dan Fluoresceinconjugated
antibodies.
Deteksi Pemeriksaan NAATs memiliki sensitifitas lebih tinggi dibandingkan
molekular kultur dan spesifisitas yang serupa dengan kultur.
Spesimen diambil dari dari swab urogenital dan vagina sehingga
skrining dapat dilakukan.
Keuntungan lainnya adalah pada pemeriksaan ini, pasien dapat
dilakukan pemeriksaan terhadap N. gonorrhoeae dan C.
trachomatis.

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 Uji serologi telah dikembangkan untuk mendeteksi antibodi
terhadap N. gonorrhoeae atau komponennya menggunakan
teknik fiksasi komplemen, imunopresipitasi, bakterial lisis,
imunofluoresens, hemaglutinasi, aglutinasi lateks, dan enzyme-
Pemeriksaan linked imunoabsorban.
serologi darah Sebagian besar uji serodiagnostik memiliki sensitifitas dan
spesifisitas yang terbatas, yaitu 70% dan 80% pada gonore non
komplikata sehingga tidak bermanfaat untuk skrining ataupun
diagnosis

THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND

LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021
Pemeriksaan
laboratoriu m
Uretritis gonore:
• PMN > 5/lpb
• Diplokokus
Gram negatif
intraseluler

Servisitis gonore:
• PMN > 30/lpb
• Diplokokus
Gram negatif
intraseluler

Sumber:
Draft final Pedoman nasional infeksi menular seksual, Kementerian Kesehatan Republik Indonesia, 2020
THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND
LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021
Pemeriksaan
laboratoriu m

Diagnosis infeksi C. trachomatis

pada pasien laki-laki dapat
dilakukan secara klinis dan
pemeriksaan lab sederhana

Pada pasien perempuan sering

asimtomatis, dan perlu
pemeriksaan NAAT

Sumber:
Draft final Pedoman nasional infeksi menular seksual, Kementerian Kesehatan Republik Indonesia, 2020
THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND
LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021
Kriteria obat berbagai IMS
• Angka kesembuhan/ kemanjuran tinggi (sekurang-
kurangnya 95% di wilayah tersebut).

• Harga murah dan terjangkau.

• Toksisitas dan toleransi masih dapat diterima.
• Pemberian dalam dosis tunggal.
• Cara pemberian per oral.
• Tidak merupakan kontra indikasi untuk ibu hamil atau
menyusui

THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND 1

LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021 9
Pengobatan
Gonore Sumber:
Draft final Pedoman nasional infeksi
menular seksual, Kementerian
THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND Kesehatan Republik Indonesia, 2020
LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021
Diskusi

THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND

LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021
Kepustakaan
1. Draft final Pedoman nasional infeksi menular seksual, Kementerian Kesehatan
Republik

Indonesia, 2020
2. Laboratory diagnosis of sexually transmitted infection, including human
immunodeficiency virus,

WHO;2013

3. CDC guideline : 2015

4. Holmes K. Sexually transmitted diseases. New York: McGraw-Hill, Health Professions
Division; 2008.

5. Cristaudo A, Giuliani M. Eds. Sexually transmitted infections. Rome, Springer Nature, 2020

THE ROLE OF MEDICAL LABORATORY TECHNOLOGY IN THE DIAGNOSIS OF GONORRHEA AND

LABORATORY EXAMINATION OF THE BACTERIA NEISSERIA GONNORRHOEAE" 07122021